Revista medica del Instituto Mexicano del Seguro Social最新文献_第4页

[Thinking, evaluating, and replenishing the fibrinogen hemostatic strategy in neurosurgery]. 神经外科中纤维蛋白原止血策略的思考、评估和补充。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-07-13 DOI: 10.5281/zenodo.19076253

Eduardo Daniel Anica-Malagón, Jorge Ariel Sosa-Bolio

{"title":"[Thinking, evaluating, and replenishing the fibrinogen hemostatic strategy in neurosurgery].","authors":"Eduardo Daniel Anica-Malagón, Jorge Ariel Sosa-Bolio","doi":"10.5281/zenodo.19076253","DOIUrl":"10.5281/zenodo.19076253","url":null,"abstract":"Hemostatic control in neurosurgery represents a major clinical challenge, in which even small variations in blood loss can critically alter intracranial pressure and neurological prognosis. Fibrinogen, the first coagulation factor to be depleted during hemorrhage, is also an early marker of coagulopathy and a key determinant of clot stability. This narrative review analyzed the scientific literature published between 2020 and 2025 in PubMed, Scopus, and the Cochrane Library, with emphasis on studies evaluating the pathophysiology, diagnosis, and targeted replacement of fibrinogen in neurosurgical patients. Through critical analysis and systematic integration of the selected studies, convergent evidence was identified demonstrating that low fibrinogen levels are associated with greater blood loss, an increased risk of intracranial rebleeding, and poorer functional outcomes. Viscoelastic test-guided administration allows dose optimization and reduction of transfusion requirements, while empirical strategies based on serum concentrations and surgical context provide safe alternatives when such technologies are unavailable. Understanding when and how to replace fibrinogen constitutes an essential component of comprehensive patient blood management in neurosurgery. This paradigm, summarized by the principle \"think, assess, and replace\", consolidates an integrated model of goal-directed neurohemostasis.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 4","pages":"e6998"},"PeriodicalIF":0.0,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148451171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Comment on the article: "Changes in the triglyceride-glucose index after one year of antiretroviral therapy"]. [对文章的评论：“抗逆转录病毒治疗一年后甘油三酯-葡萄糖指数的变化”]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-07-13 DOI: 10.5281/zenodo.19076165

Gonzalo Enrique Flores-Guamán

引用次数: 0

[Loss of eyeball and periorbital tissues due to craniofacial trauma: Clinical case]. [颅面外伤致眼球及眶周组织丧失1例]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-07-13 DOI: 10.5281/zenodo.19076340

Fernanda Jazmín Rodríguez-Ramírez, Yaira María José Rocha-Sánchez, Milagros Danieyis Dorrego-Oduardo, Gloria Patricia Sosa-Bustamante, Carlos Paque-Bautista, Alma Patricia González

{"title":"[Loss of eyeball and periorbital tissues due to craniofacial trauma: Clinical case].","authors":"Fernanda Jazmín Rodríguez-Ramírez, Yaira María José Rocha-Sánchez, Milagros Danieyis Dorrego-Oduardo, Gloria Patricia Sosa-Bustamante, Carlos Paque-Bautista, Alma Patricia González","doi":"10.5281/zenodo.19076340","DOIUrl":"10.5281/zenodo.19076340","url":null,"abstract":"Background: Globe rupture constitutes a severe form of open-globe injury and carries a guarded prognosis with a risk of permanent visual loss. The loss of the eyeball entails functional, psychological, and social repercussions that require a comprehensive approach aimed at timely diagnosis, appropriate management, and patient rehabilitation.Clinical case: A 2-year and 1-month-old male patient was brought by his mother to the pediatric emergency department after sustaining craniofacial and ocular trauma caused by the impact of a 45 kg domestic gas tank striking his face while playing at home. This resulted in rupture of the left eyeball and injury to the ipsilateral orbital tissue. Upon arrival at the pediatric emergency department, the patient was consolably crying and did not present any loss of consciousness. He was referred to a tertiary-level care facility for pediatric ophthalmology evaluation. An evisceration of the eyeball was performed, followed by placement of an intraorbital implant and a fenestrated conformer.Conclusions: Open globe trauma without a foreign body in young children, although infrequent, represents a serious ophthalmological emergency with a significant risk of permanent visual and anatomical loss. This case highlights an unusual injury mechanism in a 2-year-old child, emphasizing the vulnerability of young children in home environments and the importance of prevention.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 4","pages":"e6955"},"PeriodicalIF":0.0,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148451191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Merkel cell carcinoma: current surgical approaches and multidisciplinary treatment]. [默克尔细胞癌：目前的手术方法和多学科治疗]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-07-13 DOI: 10.5281/zenodo.19076275

Aldair Romero-López, Alexa Herrera-Ramírez, Gabriel Pérez-Esparza, Ana Laura Juárez-Carrera, José Francisco Cruz-Vargas

{"title":"[Merkel cell carcinoma: current surgical approaches and multidisciplinary treatment].","authors":"Aldair Romero-López, Alexa Herrera-Ramírez, Gabriel Pérez-Esparza, Ana Laura Juárez-Carrera, José Francisco Cruz-Vargas","doi":"10.5281/zenodo.19076275","DOIUrl":"10.5281/zenodo.19076275","url":null,"abstract":"Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine tumor with poor prognosis, requiring precise surgical management within a multidisciplinary approach. We conducted a narrative review with a structured literature search in biomedical databases (PubMed, Embase, Scopus, Web of Science) and official guidelines (NCCN, ESMO). Thirty high-quality and clinically relevant articles were selected based on methodological rigor and applicability. Wide local excision with 1-2 cm margins remains the standard of care for localized disease. Sentinel lymph node biopsy should be performed in all clinically node-negative cases, and complete lymphadenectomy is reserved for patients with confirmed nodal involvement or symptomatic disease. While surgery is essential, it is insufficient alone and must be integrated into a multidisciplinary model involving accurate staging, oncologic follow-up, and immunotherapy in advanced stages. This review highlights the crucial role of the surgeon as an active member of the comprehensive care team to improve survival and quality of life in patients with MCC.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 4","pages":"e6789"},"PeriodicalIF":0.0,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148451218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Elephantine Psoriasis. A case report]. (巨大的牛皮癣。[病例报告]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-07-13 DOI: 10.5281/zenodo.19076328

Eduardo Marín-Hernández, Katherine López-Soto, Eduardo Josué Marín-González

{"title":"[Elephantine Psoriasis. A case report].","authors":"Eduardo Marín-Hernández, Katherine López-Soto, Eduardo Josué Marín-González","doi":"10.5281/zenodo.19076328","DOIUrl":"10.5281/zenodo.19076328","url":null,"abstract":"Background: Hyperkeratotic psoriasis is a rare variant that includes forms such as elephantiasis, considered the rarest. It is characterized by thick, persistent plaques, resembling elephant skin, located mainly on the extremities and buttocks. Early detection and appropriate treatment, including systemic therapies, are essential for its management.Clinical case: A 58-year-old male patient presented in 2018 with dermatosis on his forehead, right elbow, and the backs of both hands. He was initially diagnosed with seborrheic dermatitis and chronic lichen simplex and received multiple topical therapies without improvement. In 2024, he developed new, disseminated lesions on his elbows, hands, and both legs, characterized by hyperkeratotic plaques and excoriations. A biopsy confirmed the diagnosis of elephantiasis variant hyperkeratotic psoriasis. Treatment with ustekinumab was initiated, resulting in significant improvement of the lesions.Conclusions: Elephantine psoriasis is a rare and difficult-to-treat variant, with few reported cases, which hinders the standardization of its management. Biologic therapies represent an effective alternative for improving prognosis, reducing complications, and preventing progression to other associated pathologies. Disseminating these cases is essential to expanding knowledge of this variant and optimizing available therapeutic options, for the benefit of patients.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 4","pages":"e6887"},"PeriodicalIF":0.0,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13378684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148451141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute appendicitis as a complication of Garengeot's hernia: Case report. [急性阑尾炎作为Garengeot疝气的并发症：一个病例报告]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-07-13 DOI: 10.5281/zenodo.19076316

Yahir Oliver-Balderas, Yelena Nantielly Hernández-Marchena, Martín Ramírez-Ronquillo, Patricia Berenice Bolado-García

{"title":"Acute appendicitis as a complication of Garengeot's hernia: Case report.","authors":"Yahir Oliver-Balderas, Yelena Nantielly Hernández-Marchena, Martín Ramírez-Ronquillo, Patricia Berenice Bolado-García","doi":"10.5281/zenodo.19076316","DOIUrl":"10.5281/zenodo.19076316","url":null,"abstract":"Background: Garengeot's hernia is a rare variant of femoral hernia in which the sac contains the vermiform appendix. Described by René-Jacques Croissant de Garengeot in the 18th century, it represents between 0.5% and 3% of femoral hernias, with appendicitis within the hernia being even more exceptional. It is more common in elderly women due to predisposing anatomical factors.Clinical case: A 77-year-old female patient was admitted to the emergency department with sudden and severe right inguinal pain (VAS 9/10), consistent with an incarcerated femoral hernia. During the surgical approach, acute appendicitis was identified within the hernial sac. An appendectomy and anatomical repair of the defect were performed using the McVay technique. The use of prosthetic material was ruled out due to the risk of contamination.Conclusions: Acute appendicitis in a Garengeot hernia is an exceptional clinical entity that is difficult to diagnose preoperatively and requires individualized management. The Guenther classification is a useful tool for standardizing the degree of appendiceal involvement and guiding the choice of surgical technique, especially in deciding whether to avoid using mesh in contaminated settings.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 4","pages":"e6771"},"PeriodicalIF":0.0,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148450685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Twelve-month clinical follow-up of patients diagnosed with bronchopulmonary dysplasia]. [支气管肺发育不良患者12个月临床随访]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-07-13 DOI: 10.5281/zenodo.19076229

Ana Karen Constantino-Solano, Mariana Paulina García-Bermúdez, Jorge Antonio Quirarte-Gómez, Arturo García-Galicia, Álvaro José Montiel-Jarquín, Nancy Rosalía Bertado-Ramírez, Carlos Alberto López-Bernal, Josué Cruz-Meza

{"title":"[Twelve-month clinical follow-up of patients diagnosed with bronchopulmonary dysplasia].","authors":"Ana Karen Constantino-Solano, Mariana Paulina García-Bermúdez, Jorge Antonio Quirarte-Gómez, Arturo García-Galicia, Álvaro José Montiel-Jarquín, Nancy Rosalía Bertado-Ramírez, Carlos Alberto López-Bernal, Josué Cruz-Meza","doi":"10.5281/zenodo.19076229","DOIUrl":"10.5281/zenodo.19076229","url":null,"abstract":"Background: Bronchopulmonary dysplasia (BPD) is a chronic disease with a high prevalence in premature infants. Its development is related to multiple risk factors, including prolonged oxygen use, mechanical ventilation, and the presence of infections.Objective: To analyze the clinical characteristics and factors associated with readmission in patients with bronchopulmonary dysplasia after 12 months of follow-up.Materials and methods: This was an observational, analytical, and longitudinal study. Patients born before 36 weeks of gestation with BPD, seen in the Pediatric Pulmonology outpatient clinic between September 2023 and August 2024, were included.Results: Eighty-one patients were analyzed. The median gestational age was 30 weeks (IQR 5; 25th percentile: 28 weeks; 75th percentile: 33 weeks); 53% were female, and 64.2% presented with moderate BPD. All patients had at least one hospital readmission. 61.7% presented with retinopathy of prematurity. 30% required oxygen for more than one year. A significant association was found between low birth weight at one year and a higher number of readmissions (OR: 9.08; 95% CI: 2.10-39.2; p = 0.002).Conclusions: The clinical course of patients with bronchopulmonary dysplasia (BPD) remains unfavorable. Low birth weight at one year was the main factor associated with readmissions. Nutritional monitoring and infection prevention strategies are needed to improve long-term prognosis.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 4","pages":"e6943"},"PeriodicalIF":0.0,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148451178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Efficacy and safety of dual anti-platelet aggregation short post-pharmacologic stent]. 双重抗血小板聚集短药后支架的疗效和安全性。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-07-13 DOI: 10.5281/zenodo.19076266

Aurelio Alejandro Ramírez-Delgadillo, Leonardo Ramírez-de la Cruz, Cesar Emiliano Jiménez-Limón, Diego Alejandro Ruiseco-Chenhalls, Cesar David Montes-González, Gabriel Sebastián Alonso-Limón

{"title":"[Efficacy and safety of dual anti-platelet aggregation short post-pharmacologic stent].","authors":"Aurelio Alejandro Ramírez-Delgadillo, Leonardo Ramírez-de la Cruz, Cesar Emiliano Jiménez-Limón, Diego Alejandro Ruiseco-Chenhalls, Cesar David Montes-González, Gabriel Sebastián Alonso-Limón","doi":"10.5281/zenodo.19076266","DOIUrl":"10.5281/zenodo.19076266","url":null,"abstract":"The objective of this systematic review is to evaluate the efficacy and safety of short-duration dual antiplatelet therapy (< 6 months) compared with prolonged therapy (> 12 months) following drug-eluting stent implantation. A systematic search was conducted in databases such as PubMed and Google Scholar for articles published between 2019 and 2025, focusing on randomized clinical trials, observational studies, and recent meta-analyses. The primary outcomes analyzed were major ischemic events (cardiovascular death, myocardial infarction, stent thrombosis), major bleeding, and all-cause mortality. Available evidence demonstrates that short-duration dual antiplatelet therapy is non-inferior to prolonged therapy in preventing major adverse cardiovascular events and is consistently associated with a significant reduction in the risk of major bleeding. This strategy offers a superior net clinical benefit when an individualized de-escalation approach is applied, particularly with the use of new-generation drug-eluting stents, supporting the abbreviated regimen as a viable recommendation and, for many patients at high bleeding risk, the preferred option. These findings underscore the importance of integrating ischemic-bleeding risk profiles into personalized therapeutic decision-making.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 4","pages":"e7031"},"PeriodicalIF":0.0,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13378687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148451156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Predictive capacity of 30-day mortality using the Nottingham Scale in people aged 65 years or older with hip fracture in Michoacán]. [使用诺丁汉量表预测65岁及以上髋部骨折患者30天死亡率的能力[Michoacán]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-07-13 DOI: 10.5281/zenodo.19076235

Daniela Guadalupe Damian-Nuevo, José Octavio Duarte-Flores, José Francisco Méndez-Delgado

{"title":"[Predictive capacity of 30-day mortality using the Nottingham Scale in people aged 65 years or older with hip fracture in Michoacán].","authors":"Daniela Guadalupe Damian-Nuevo, José Octavio Duarte-Flores, José Francisco Méndez-Delgado","doi":"10.5281/zenodo.19076235","DOIUrl":"10.5281/zenodo.19076235","url":null,"abstract":"Background: Hip fracture is a high-morbidity and high-mortality event in older adults. Early identification of the risk of death allows for optimized therapeutic decisions.Objective: To evaluate the predictive capacity of the Nottingham Hip Fracture Scale (NHFS) for estimating 30-day mortality in individuals aged 65 years or older with a hip fracture.Material and methods: A prospective, observational, longitudinal study was conducted in two IMSS hospitals in Michoacán, Mexico. Patients aged 65 years or older with a hip fracture were included. The NHFS score and its discriminative capacity were calculated using receiver operating characteristic (ROC) curve analysis.Results: 169 patients were included; the 30-day mortality rate was 14.2%. Hemoglobin < 10 g/dL showed the strongest association with mortality, followed by in-hospital delirium and the NHFS score. In the multivariable model, severe anemia remained an independent predictor. The discriminative capacity of the scale was moderate (AUC = 0.746). The optimal cutoff point was ≥ 5 points.Conclusions: The Nottingham scale showed moderate discriminatory ability to predict 30-day mortality. Severe anemia emerged as an independent predictor of mortality.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 4","pages":"e7012"},"PeriodicalIF":0.0,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13378686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148451200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Characterization of immune reconstitution inflammatory syndrome in a Mexican cohort]. [墨西哥队列中免疫重建炎症综合征的特征]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-07-13 DOI: 10.5281/zenodo.19076187

Edwin Jeffry Palma-Díaz, Alejandra Albarrán-Sánchez, Maura Estela Noyola-García, Elsy Estefania Pérez-Pedraza

{"title":"[Characterization of immune reconstitution inflammatory syndrome in a Mexican cohort].","authors":"Edwin Jeffry Palma-Díaz, Alejandra Albarrán-Sánchez, Maura Estela Noyola-García, Elsy Estefania Pérez-Pedraza","doi":"10.5281/zenodo.19076187","DOIUrl":"10.5281/zenodo.19076187","url":null,"abstract":"Background: Immune reconstitution inflammatory syndrome (IRIS) is an exaggerated inflammatory response to previously acquired opportunistic pathogens, causing clinical deterioration in the first months after starting antiretroviral therapy, contributing to morbidity and mortality in people living with HIV (PLHIV). In Mexico, data are limited, but IRIS has been reported in 11.4 - 27% of patients, with Varicella zoster as the most frequently associated pathogen and a mortality rate of 4.9 deaths per 100 person-years.Objective: To describe clinical and etiological characteristics of immune reconstitution inflammatory syndrome in patients treated at a tertiary care hospital in Mexico.Material and methods: A cross-sectional, retrospective study, through the review of medical records from the Hospital de Especialidades CMN Siglo XXI, including patients with recent HIV diagnosis between January 1, 2017, and June 31, 2023. Variables were recorded and analyzed using SPSS v.25, with p < 0.05 considered statistically significant.Results: 55 patients were included; 45 (81.8%) presented unmasking IRIS, with a median onset time of 6 (4-12) weeks after starting ART. M. tuberculosis was the most frequent pathogen (27.3%). There were eight deaths (14.5%), due to pneumocystis pneumonia and cerebral toxoplasmosis. Corticosteroid use was associated with higher mortality.Conclusions: The most frequent pathogens associated with IRIS were M. tuberculosis and cytomegalovirus. The case-fatality rate was 14.5%, higher than that reported in other Mexican series.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 4","pages":"e6980"},"PeriodicalIF":0.0,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13375251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148451164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0