{"title":"[Nested variant of urothelial carcinoma complicated with pulmonary lymphangitis carcinomatosis. Case report].","authors":"Gerardo Abraham Pale-González, Huber Díaz-Fuentes","doi":"10.5281/zenodo.21462924","DOIUrl":"10.5281/zenodo.21462924","url":null,"abstract":"<p><strong>Background: </strong>Nested variant of urothelial carcinoma is a rare entity characterized by a particularly aggressive clinical course and a poor prognosis. Although disease progression can involve the lung parenchyma, pulmonary carcinomatous lymphangitis is an exceptionally rare manifestation. Up until the date of this publication, evidence in literature is limited, highlighting the rarity of this pattern of dissemination and the importance of its timely recognition.</p><p><strong>Clinical case: </strong>A 72-year-old man with initial macroscopic hematuria, who was diagnosed with nested variant of urothelial carcinoma with infiltration of the lamina propria. Despite transurethral resection of the tumor and subsequent systemic treatment with platinum-based chemotherapy, the patient experienced rapid disease progression, which was characterized by pelvic and mediastinal lymph node infiltration, pulmonary lymphangitic dissemination, bilateral hydronephrosis, and thrombosis of the right internal jugular vein, as well as the left common iliac, external iliac, and femoral veins.</p><p><strong>Conclusions: </strong>This report documents a case of muscle invader nested variant of urothelial carcinoma, whose evolution was complicated by pulmonary carcinomatous lymphangitis, an extremely rare manifestation. Early recognition of this variant is essential to guide the diagnostic and therapeutic approach in patients with high-risk histological variants.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7099"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Interpretation of effect measures in clinical research: A practical guide for the clinician].","authors":"Angelica Jeanette Luevanos-Aguilera","doi":"10.5281/zenodo.21462788","DOIUrl":"10.5281/zenodo.21462788","url":null,"abstract":"<p><p>Modern medical practice faces an ever-growing volume of information that demands accurate statistical interpretation to guide clinical decision-making. Effect measures are essential tools for quantifying the true magnitude of an intervention and assessing its clinical impact. However, limited understanding of these measures among healthcare professionals often hinders the effective translation of evidence into everyday practice. This article's objective is to provide a clear and didactic overview of the principal effect measures used in clinical research, emphasizing their relevance to evidence-based medicine. Key concepts such as the p-value, confidence intervals, relative risk, absolute risk reduction, and number needed to treat are summarized. The p-value reflects statistical significance, but it does not convey the magnitude or clinical importance of an effect. Confidence intervals, on the other hand, offer information about the precision and direction of the estimated effect. Relative risk facilitates the comparison of probabilities between groups, while absolute risk reduction and number needed to treat provide more tangible measures for clinical application. The adequate interpretation of these concepts is a cornerstone of evidence-based medicine, it enables clinicians to critically appraise research findings, and make patient-centered decisions, thereby narrowing the gap between scientific evidence and clinical practice.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e6907"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13600739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Humberto Medina-Chávez, Alejandro Herrera-Landero, Luis Efrén Santos-Martínez, Luis Antonio Moreno-Ruiz
{"title":"[Development, structure, and function of the GeriatrIMSS Institutional Model].","authors":"Juan Humberto Medina-Chávez, Alejandro Herrera-Landero, Luis Efrén Santos-Martínez, Luis Antonio Moreno-Ruiz","doi":"10.5281/zenodo.21462843","DOIUrl":"10.5281/zenodo.21462843","url":null,"abstract":"<p><p>The increase in life expectancy over recent decades has led to a significant growth in the older adult population, resulting in an unprecedented demographic transition and generating substantial costs for the health care system. In response to this situation, the Mexican Institute for Social Security (IMSS) implemented the Institutional Geriatric Plan GeriatrIMSS, a comprehensive strategy designed to address individuals with greater physiological vulnerability and a high prevalence of non-communicable diseases. This plan aims to strengthen IMSS operational capacities and to reorient processes and services in order to provide an appropriate response to the specific needs of this population group, thereby improving medical care for older beneficiaries. GeriatrIMSS is based on 4 fundamental pillars: prevention (PREVENIMSS), comprehensive geriatric care, education, and research. Through this strategy, IMSS positions itself at the international forefront of older adult care, addressing the main health challenges faced by this population and providing preventive, comprehensive, and interdisciplinary care. This approach seeks to improve the quality of care and increase satisfaction among both users and their families. The purpose of this article was to present the development, structure, and functioning of the GeriatrIMSS Institutional Geriatric Care Model.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7179"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13632694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Anomalous origin of the right pulmonary artery: Non-invasive diagnosis and early surgery].","authors":"Víctor Osiel Serrano-Ramírez, Guillermo Godoy-Rábago, Martha Angélica Contreras-Ortega","doi":"10.5281/zenodo.21462881","DOIUrl":"10.5281/zenodo.21462881","url":null,"abstract":"<p><strong>Background: </strong>The anomalous origin of a branch of the pulmonary artery from the ascending aorta (AORPA) is a rare congenital heart disease accounting for approximately 0.12% of congenital heart defects, associated with high mortality rates, up to 70%, if not treated in a timely manner. The clinical spectrum ranges from asymptomatic presentation to pulmonary hypertension and heart failure in the neonatal period.</p><p><strong>Clinical case: </strong>2-month-old breastfed infant with anomalous origin of the right pulmonary artery from the ascending aorta, initially suspected due to the presence of a cardiac murmur and a positive cardiac screening. Echocardiography and computed tomography angiography confirmed the diagnosis, showing no stenosis of the anomalous branch and no significant pulmonary hypertension as estimated by non-invasive methods. Surgical reimplantation was performed with anastomotic enlargement using bovine pericardium. The postoperative course was complicated by transient respiratory issues, with a favorable clinical outcome.</p><p><strong>Conclusions: </strong>This case supports the usefulness of echocardiography and computed tomography angiography as tools for accurate anatomical diagnosis and based on each individual case for planning treatment. Furthermore, it reaffirms that, based on the specific anatomical characteristics of each case, direct reimplantation is not always the surgical technique of choice.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7051"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13600738/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis Javier Hernández-García, Mauri López-Ahumada, Ignacio Mariscal-Ramírez, Óscar Rosas-Carrasco, María Claudia Espinel-Bermúdez, Hugo Alonso Rodríguez-Ortega, José Brayan Picazo-Turrado, Betsabé Contreras-Haro
{"title":"[Suspicion of sarcopenia as a predictor of toxicity in older people with cancer].","authors":"Luis Javier Hernández-García, Mauri López-Ahumada, Ignacio Mariscal-Ramírez, Óscar Rosas-Carrasco, María Claudia Espinel-Bermúdez, Hugo Alonso Rodríguez-Ortega, José Brayan Picazo-Turrado, Betsabé Contreras-Haro","doi":"10.5281/zenodo.21462656","DOIUrl":"10.5281/zenodo.21462656","url":null,"abstract":"<p><strong>Background: </strong>Functional status is considered the standard criterion prior to systemic therapy administration; however, in older adults with cancer, this criterion may lead to challenges in this group.</p><p><strong>Objective: </strong>To evaluate the association between suspicion of sarcopenia and systemic treatment toxicity in older adults with cancer.</p><p><strong>Material and methods: </strong>Prospective cohort study which included 150 older adults with recent diagnosis of cancer, candidates to systemic cancer treatment and who signed informed consent. Older adults with brain metastasis were excluded. Prior to systemic treatment, functional status variables were evaluated: skeletal muscle strength, sarcopenia screening, frailty, and chair stand test. Follow-up evaluations were performed before each systemic treatment cycle. Endpoint was considered as the clinical evidence or laboratory toxicity grade 3 or higher, using the Common Terminology Criteria for Adverse Events, version 5.0, or the completion of the treatment regimen.</p><p><strong>Results: </strong>The incidence of systemic toxicity was 42.7%. In the comparison between patients without toxicity vs. patients with toxicity, the latter group showed a higher frequency of tobacco use, frailty, risk of sarcopenia, and lower grip strength. Only sarcopenia screening predicted systemic toxicity (hazard ratio [HR]: 2.13, 95% confidence interval [95% CI] 1.16-3.91).</p><p><strong>Conclusions: </strong>The suspicion of sarcopenia was the only toxicity predictor for systemic therapy in older adults with cancer.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e6960"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13600735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinicopathological characteristics of human epidermal growth factor receptor-2 1+ cases in breast cancer].","authors":"Yamileth Sánchez-Corona, Enoe Enedina Quiñonez-Urrego","doi":"10.5281/zenodo.21462775","DOIUrl":"10.5281/zenodo.21462775","url":null,"abstract":"<p><strong>Background: </strong>The expression of the HER2 oncogene has a specific prognostic and therapeutic objective in breast cancer care. Low gene expression, called HER2-low implies the possibility of being a candidate for targeted therapy. However, there is significant variability in its interpretation, hence the importance of emphasizing its proper identification and reporting.</p><p><strong>Objective: </strong>To estimate the proportion of cases confirmed as HER2 1+ among biopsies previously reported as HER2 1+, and to describe their clinicopathological characteristics, as well as the interobserver agreement in their classification.</p><p><strong>Materials and methods: </strong>Observational, retrospective, and analytical study of cases previously diagnosed as HER2-negative score 1+, which were reviewed by 2 independent pathologists.</p><p><strong>Results: </strong>351 cases were included, with a mean age of 59.56 years. The histological subtypes were invasive ductal carcinoma NOS (70.66%), histological grade 2 (56.92%), and SBR score 6 (41.82%), associated in 89.17% of cases with hormone receptor expression. There was agreement for the HER2-low diagnosis in 78.91% of cases, with a Cohen's kappa simple of 0.62, which is similar to some studies documented in the literature.</p><p><strong>Conclusions: </strong>Agreement in the interpretation of HER2-low increases when it is performed by at least 2 pathologists; likewise, proper handling of surgical specimens in the pre-analytical phase is vital for optimal assessment, as this has a direct impact on current prognosis and treatment.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e6875"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13600743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adoración Morales-Ibarra, Jessy Ángeles-Ruedas, Mauricio Daniel León-Yepez, Melissa Barajas-Martínez, Najla Maresa Villegas-Ponce, Abril Adriana Arellano-Llamas
{"title":"[Obesity during pregnancy is associated to congenital cardiopathies in the newborn].","authors":"Adoración Morales-Ibarra, Jessy Ángeles-Ruedas, Mauricio Daniel León-Yepez, Melissa Barajas-Martínez, Najla Maresa Villegas-Ponce, Abril Adriana Arellano-Llamas","doi":"10.5281/zenodo.21462746","DOIUrl":"10.5281/zenodo.21462746","url":null,"abstract":"<p><strong>Background: </strong>Congenital heart disease (CHD) has a high burden of disease in terms of morbidity and mortality in children under 5 years. Maternal obesity (MO) could be a significant risk for developing CHD.</p><p><strong>Objective: </strong>To analyze the associated risk of CHD in newborns according to MO.</p><p><strong>Material and methods: </strong>Retrospective analytical and transversal design of newborns studied by echocardiography, with a 1:1 relationship between newborns with vs. without CHD. Maternal age, maternal body mass index (BMI), gestational age at birth, and birth weight were collected. Bivariate and multivariate analyses using binary logistic regression were conducted to calculate odds ratios (OR) and evaluate the association between maternal nutritional status and CHD in the newborn, adjusting for maternal age.</p><p><strong>Results: </strong>We analyzed 800 newborns from 785 pregnancies (15 twin pregnancies). The prenatal mother's BMI was 24.38 kg/m2, and 26.7% were obese. Bivariate analysis showed significant differences in sex (female 41% vs. 54%), gestational age (37 vs. 36 weeks), and MO (7% vs. 19.9%). Regression analysis showed that maternal BMI (beta 0.156, IC 95% Exp beta 1.118-1.222, p = 0.0001), obesity (OR 5.23, IC 95% 3.26-8.39, p = 0.0001), and female sex (OR 1.38, IC 95% 0.977-1.966, p = 0.067) have an associated risk of cardiopathy.</p><p><strong>Conclusions: </strong>MO is a significant risk factor for CHD in Mexico. It is urgent to take public health measures to control MO, and all newborns of mothers affected by MO must have a screening for congenital heart disease.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7147"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Melissa Peña-Durán, Gloria Paulina Trujillo-Sánchez, Luis Miguel López-Montero
{"title":"[Work reintegration in patients treated for diabetic macular edema].","authors":"Sarah Melissa Peña-Durán, Gloria Paulina Trujillo-Sánchez, Luis Miguel López-Montero","doi":"10.5281/zenodo.21462625","DOIUrl":"10.5281/zenodo.21462625","url":null,"abstract":"<p><strong>Background: </strong>Type 2 diabetes mellitus (T2DM) has increased in prevalence, and with it, complications such as diabetic retinopathy and diabetic macular edema (DME), which cause disability due to visual impairment and high medical and social costs, as it is the leading cause of blindness in the economically active population aged 18 to 64. Intravitreal anti-angiogenic (anti-VEGF) therapy is the first line of treatment.</p><p><strong>Objective: </strong>To estimate the proportion of patients with DME who return to work and the time required after treatment.</p><p><strong>Material and methods: </strong>Based on literature and local data with a response rate ≥ 60%, an observational study was planned; the analysis was descriptive, and the post-intervention comparison was performed using the chi-square test.</p><p><strong>Results: </strong>45 patients were included (26 women, 19 men; 57.4 ± 5.0 years; T2DM duration 16 [12-20] years), with diabetic retinopathy and macular edema: proliferative 53.3%, mild non-proliferative 22.2%, severe 17.8%, moderate 6.7%. Functional success (visual acuity, [VA] ≥ 0.5) was achieved in 70% of mild non-proliferative cases and 25% of proliferative/severe cases. Mean gain in decimal VA was + 0.127 RE and + 0.090 LE. A total of 33.3% reached VA ≥ 0.5 after loading doses, a functional level compatible with reading and precision tasks. An inverse correlation was observed between central macular thickness and final VA.</p><p><strong>Conclusions: </strong>Early intervention maximized the benefit with intravitreal anti-VEGF, improving function and anatomy in DME. A significant proportion of patients of working age returned to work, reducing days of disability and improving quality of life.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7061"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13610904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Alberto Godínez-Chaparro, Rodrigo Roldán-Marín, Helena Vidaurri-de la Cruz
{"title":"[Dermatoscopic \"sky full of stars\" pattern in a congenital melanocytic nevus with follicular distribution].","authors":"Juan Alberto Godínez-Chaparro, Rodrigo Roldán-Marín, Helena Vidaurri-de la Cruz","doi":"10.5281/zenodo.21462915","DOIUrl":"10.5281/zenodo.21462915","url":null,"abstract":"<p><strong>Background: </strong>Congenital melanocytic nevus (CMN) is present at birth or appears during the first year of life. Certain dermoscopic features allow differentiation from other pigmented lesions and assessment of its evolution. We report a case of CMN with melanocytic distribution limited to hair follicles, associating dermoscopic findings with reflectance confocal microscopy (RCM).</p><p><strong>Case report: </strong>A 2 year and 7 month old male patient with no relevant medical history presented with a 10 × 7 mm melanocytic macule on the left posterior lumbar region, present since birth. Dermoscopy revealed a central gray-blue area with dark brown globules distributed perifollicularly and radially from the follicular ostium, forming a \"sky full of stars\" pattern. RCM showed melanocytic proliferation at the dermoepidermal junction, organized in dense aggregates and nests, with a mixed mesh and globular pattern.</p><p><strong>Conclusions: </strong>Perifollicular aggregates observed on dermoscopy correspond to melanin deposits within follicular openings. The \"sky full of stars\" pattern, which has been rarely described, may be associated with melanocytes confined to the infundibulum and noncontiguous hair follicles. It is important to differentiate this pattern from the globular pattern, which indicates melanocytic activity. RCM may provide useful information for clinical follow-up.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7078"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13610911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis Efrén Santos-Martínez, Nancy Imelda Colín-Chávez, Jessica Paola Durán-Vidauri, Martha Vianey Ureña-Plascencia, Alejandro Moctezuma-Paz, Francisco Javier González-Ruiz, Luis Antonio Moreno-Ruiz
{"title":"[Reproducibility of pulse oximetry in the fingers of the hands].","authors":"Luis Efrén Santos-Martínez, Nancy Imelda Colín-Chávez, Jessica Paola Durán-Vidauri, Martha Vianey Ureña-Plascencia, Alejandro Moctezuma-Paz, Francisco Javier González-Ruiz, Luis Antonio Moreno-Ruiz","doi":"10.5281/zenodo.21462637","DOIUrl":"10.5281/zenodo.21462637","url":null,"abstract":"<p><strong>Background: </strong>Partial oxygen saturation from pulse oximetry is most often obtained from the fingers of the hands; however, it is not known whether any of the fingers are ideal for estimating partial oxygen saturation.</p><p><strong>Objective: </strong>To describe the partial oxygen saturation behaviour obtained from the fingers of both hands.</p><p><strong>Material and methods: </strong>Using a cross-sectional analytical design, the partial oxygen saturation was consecutively estimated in the fingers of both hands. Demographic data were obtained from healthy subjects, and they were analyzed using repeated-measures analysis of variance; reproducibility was calculated using the mean difference (limits of agreement) and its magnitude using the intraclass correlation coefficient or ICC (95% confidence interval [95% CI]); a p value < 0.05 was considered significant.</p><p><strong>Results: </strong>1000 determinations of partial oxygen saturation were studied from the fingers of both hands of 100 subjects (64% women) whose average age was 34 ± 10 years old and whose body mass index (BMI) was of 23.5 ± 5 kg/m2. Partial oxygen saturation was 90.3 ± 4% and reproducibility was almost perfect in all combinations; however, the right index finger versus right ring finger combination was the best: 90.3 ± 4.1% versus 90.5 ± 4% mean difference (limits of agreement) -0.2 (2.5, -2.8) between both and the ICC (95% CI) 0.942 (0.916, 0.961).</p><p><strong>Conclusions: </strong>Partial oxygen saturation is reproducible in all fingers, with no clinically relevant differences.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7083"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13610912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}