Revista medica del Instituto Mexicano del Seguro Social最新文献_第2页

[Comment to the article "Clinical-pathological characterization of laryngeal cancer in the Mexican population"]. [对文章“墨西哥人群喉癌的临床病理特征”的评论]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-07-01 DOI: 10.5281/zenodo.15644291

María Fernanda Galindo-Tapia

引用次数: 0

Comprehensive study of associated factors with Type 2 Diabetes in Mexico: protocol. 墨西哥2型糖尿病相关因素的综合研究：方案

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-07-01 DOI: 10.5281/zenodo.15644323

Aldo Ferreira-Hermosillo, Rodolfo Rivas-Ruiz, Ivonne Analí Roy-García, Eduardo Antonio Ferat-Osorio, Octavio Castro-Escamilla, Keiko Taniguchi-Ponciano, Daniel Marrero-Rodríguez, Amelia Irene Rodríguez-Jiménez, Patricia Pérez-Zataray, Jose Luis Cevallos-Rivera, Jorge A Hernández-Casildo, José Félix Saavedra-Ramírez, Víctor G Cruz-Morales, Omar Livio Peralta-Méndez, Alejandro M Vargas-García, Asa Christina Laurell, Rosana Pelayo, Laura C Bonifaz

{"title":"Comprehensive study of associated factors with Type 2 Diabetes in Mexico: protocol.","authors":"Aldo Ferreira-Hermosillo, Rodolfo Rivas-Ruiz, Ivonne Analí Roy-García, Eduardo Antonio Ferat-Osorio, Octavio Castro-Escamilla, Keiko Taniguchi-Ponciano, Daniel Marrero-Rodríguez, Amelia Irene Rodríguez-Jiménez, Patricia Pérez-Zataray, Jose Luis Cevallos-Rivera, Jorge A Hernández-Casildo, José Félix Saavedra-Ramírez, Víctor G Cruz-Morales, Omar Livio Peralta-Méndez, Alejandro M Vargas-García, Asa Christina Laurell, Rosana Pelayo, Laura C Bonifaz","doi":"10.5281/zenodo.15644323","DOIUrl":"10.5281/zenodo.15644323","url":null,"abstract":"One of the main goals in the treatment of patients with type 2 diabetes (T2D) is the prevention of its complications. Most existing studies have evaluated a limited and isolated number of inflammatory molecules and metabolic factors, and only rarely have clinical and lifestyle variables been jointly considered. The objective of this study is to describe the protocol design for a comprehensive assessment of patients with T2D, considering glycemic control and the development of complications. A cross-sectional, observational, and multicenter study was conducted in three primary care units located in the states of Coahuila, Jalisco, and Veracruz. Glycemic dysregulation will be assessed by measuring glycated hemoglobin, while diabetic nephropathy will be identified through alterations in the glomerular filtration rate. Additionally, clinical and biochemical parameters, lifestyle habits, physical condition, type of treatment, treatment adherence, and nutritional aspects will be evaluated. Furthermore, transcriptomic analysis using RNA-Seq will be performed to identify the genes that best stratify and distinguish patients with glycemic dysregulation, metabolic alterations, and diabetic nephropathy through principal component analysis and ROC curves based on relative RNA expression. To determine clinical factors associated with the link between molecular profiles and glycemic dysregulation, multiple logistic regression models will be developed to identify a pathological molecular signature characteristic of the disease.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 4","pages":"e6386"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144639171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[High glucose levels in children at diagnosis of acute lymphoblastic leukemia]. [儿童急性淋巴细胞白血病诊断时的高血糖]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-07-01 DOI: 10.5281/zenodo.15850431

Carlos Paque-Bautista, Sara Aurora Aranda-Romo, Andrea Medel-Sánchez, Alma Patricia González, Dania Eunice Cerritos-García, Arturo Maximiliano Reyes-Sosa, Gloria Patricia Sosa-Bustamante

{"title":"[High glucose levels in children at diagnosis of acute lymphoblastic leukemia].","authors":"Carlos Paque-Bautista, Sara Aurora Aranda-Romo, Andrea Medel-Sánchez, Alma Patricia González, Dania Eunice Cerritos-García, Arturo Maximiliano Reyes-Sosa, Gloria Patricia Sosa-Bustamante","doi":"10.5281/zenodo.15850431","DOIUrl":"10.5281/zenodo.15850431","url":null,"abstract":"Background: Acute lymphoblastic leukemia (ALL) is the most common neoplasm in children. Although survival rates have improved, considerable mortality persists, partly due to metabolic complications. ALL is characterized by metabolic reprogramming, which may clinically manifest as elevated serum glucose (SG) levels at disease onset.Objective: To analyze whether there are differences in SG levels between newly diagnosed pediatric patients with ALL and a control group.Materials and methods: A case-control study was conducted. Pediatric patients aged between 1 month and 15 years 11 months, of both sexes, were included and divided into two groups. ALL Group: Patients with a recent diagnosis of ALL, prior to the initiation of induction therapy. Control Group: Patients without a diagnosis of ALL. Sociodemographic, anthropometric, and biochemical data were obtained from clinical records.Results: A total of 142 patients were analyzed, 71 in the ALL Group and 71 in the Control Group. The median age was 6 years (IQR 3-11), and 54.92% were male. The ALL Group showed significantly higher SG levels compared to the Control Group. In addition, a higher risk of elevated SG was observed in the ALL Group.Conclusions: This study demonstrates elevated SG levels in children with newly diagnosed ALL, which may be related to the metabolic reprogramming of leukemic cells.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 4","pages":"e6664"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12283111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Postoperative result in appendectomy with Pouchet technique versus other surgical techniques]. [小袋技术与其他手术技术比较阑尾切除术的术后结果]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-07-01 DOI: 10.5281/zenodo.15644313

Antonio Jhonatan Hernández-Flores, Sergio Elihu Rodríguez-Alfaro, Raúl Mendoza-Rodríguez, Socorro Méndez-Martínez, Jorge Ayón-Aguilar, Máximo Alejandro García-Flores, Israel Aguilar-Cózatl

{"title":"[Postoperative result in appendectomy with Pouchet technique versus other surgical techniques].","authors":"Antonio Jhonatan Hernández-Flores, Sergio Elihu Rodríguez-Alfaro, Raúl Mendoza-Rodríguez, Socorro Méndez-Martínez, Jorge Ayón-Aguilar, Máximo Alejandro García-Flores, Israel Aguilar-Cózatl","doi":"10.5281/zenodo.15644313","DOIUrl":"10.5281/zenodo.15644313","url":null,"abstract":"Background: Acute appendicitis is the most common surgical emergency worldwide. Closure of the appendiceal stump is a critical step to prevent postoperative complications.Objective: To compare postoperative outcomes of appendectomy using the Pouchet technique versus other appendiceal stump closure techniques.Material and methods: This retrospective study analyzed medical records of patients over 18 years of age who underwent surgery for acute appendicitis at a secondary-level hospital. Postoperative outcomes were assessed based on the presence of infectious complications, operative time, and length of hospital stay, comparing the surgical techniques used: Pouchet, Halsted, Zuckerman, and Parker. Descriptive and inferential statistics were applied, using the chi-square test to estimate differences in postoperative outcomes, with a significance level of ≤ 0.05.Results: A total of 118 medical records were analyzed, of which 70 corresponded to female patients (59.3%), with a median age of 39 years (interquartile range: 18-92 years). The most commonly used surgical techniques were: Pouchet (74 cases; 62.7%), Halsted (27; 22.8%), Zuckerman (12; 10.1%), and Parker (5; 4.2%). The Pouchet and Halsted techniques showed statistically significant differences compared to other techniques in terms of shorter operative time and hospital stay (p = 0.000 and p = 0.011, respectively). Additionally, the Pouchet and Parker techniques were associated with statistically significant differences in the incidence of infectious complications (p = 0.030).Conclusions: The Pouchet technique demonstrated the best postoperative outcomes in terms of operative time, hospital stay duration, and lower incidence of infectious complications.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 4","pages":"e6168"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12286647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Impact of an educational intervention on knowledge, attitudes, and practices on breastfeeding]. [评论文章“教育干预对母乳喂养知识、态度和实践的影响”]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-07-01 DOI: 10.5281/zenodo.15644270

Augusto Rafael Aguilera-Joaquin

引用次数: 0

[Diagnosis and treatment of pediatric acute lymphoblastic leukemia: Historical review]. 【儿童急性淋巴细胞白血病的诊断和治疗：历史回顾】。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-07-01 DOI: 10.5281/zenodo.15644329

Betzayda Valdez-Garibay, Gloria Patricia Sosa-Bustamante, Alma Patricia González, Benigno Linares-Segovia, Octavio Martínez-Villegas, Arturo Maximiliano Reyes-Sosa, Carlos Paque-Bautista

{"title":"[Diagnosis and treatment of pediatric acute lymphoblastic leukemia: Historical review].","authors":"Betzayda Valdez-Garibay, Gloria Patricia Sosa-Bustamante, Alma Patricia González, Benigno Linares-Segovia, Octavio Martínez-Villegas, Arturo Maximiliano Reyes-Sosa, Carlos Paque-Bautista","doi":"10.5281/zenodo.15644329","DOIUrl":"10.5281/zenodo.15644329","url":null,"abstract":"Acute lymphoblastic leukemia (ALL) is the most common malignant neoplasm in childhood, with the highest incidence occurring between 10 and 14 years of age in the Mexican population. ALL results from the abnormal proliferation of a malignant clone of leukocytes. The Mexican pediatric population exhibits idiosyncratic characteristics that are associated with a less favorable prognosis compared to the Caucasian population. In 1847, Rudolph Virchow first coined the term leukemia. In 1976, the French-American-British classification was introduced, which described the morphological characteristics of leukemic cells as L1, L2, and L3, providing greater diagnostic accuracy and distinguishing between myeloid and lymphoid leukemia. At that time, the disease-free survival rate was 20%. In 2008, the World Health Organization (WHO) introduced an immunological classification based on the immunophenotype of leukemias, marking a new era in the prognosis and clinical management of the disease. This classification reduced interobserver morphological diagnostic errors by identifying antigens that classify the cell lineage and maturation stage. The expression and combination of cellular antigens, as well as molecular rearrangements, are directly associated with the prognosis of ALL. Treatment has evolved alongside diagnostic advances in recent years, with strategies aimed at limiting treatment-related toxicity through safer chemotherapy regimens.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 4","pages":"e6552"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144639150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Tribute to Dr. Felipe Cruz Vega (1944-2025)]. [向费利佩·克鲁兹·维加博士（1944-2025）致敬]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-07-01 DOI: 10.5281/zenodo.15644349

Guillermo Fajardo-Ortiz, Alejandro Moctezuma-Paz, Oscar Cruz-Orozco

引用次数: 0

[Comment on the article: "Neutrophil-lymphocyte ratio as predictor of mortality in patients with necrotizing fasciitis"]. [评论文章：“中性粒细胞-淋巴细胞比率作为坏死性筋膜炎患者死亡率的预测因子”]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-07-01 DOI: 10.5281/zenodo.15644245

Ana Karen Luna-Vargas

引用次数: 0

[A New Era for the Scientific Journals of the IMSS]. [IMSS科学期刊的新时代]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-07-01 DOI: 10.5281/zenodo.15644206

Alejandro Moctezuma-Paz, Omar Chávez-Martínez, Guillermo Fajardo-Ortiz

引用次数: 0

[Comment on the article: "Cognition in pediatric patients with diagnosis of epilepsy"]. [对《小儿癫痫诊断患者的认知》一文的评论]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-07-01 DOI: 10.5281/zenodo.15644226

Ricardo Dorantes-López

引用次数: 0