Revista medica del Instituto Mexicano del Seguro Social最新文献

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[Avian influenza: a latent challenge]. [禽流感:潜伏的挑战]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.12668094
David Alejandro Cabrera-Gaytán
{"title":"[Avian influenza: a latent challenge].","authors":"David Alejandro Cabrera-Gaytán","doi":"10.5281/zenodo.12668094","DOIUrl":"https://doi.org/10.5281/zenodo.12668094","url":null,"abstract":"<p><p>The avian influenza virus was first identified in China in 1996, but it was in 2021 when numerous outbreaks of avian influenza began in different regions of the world, including Mexico. This virus has caused a significant impact on animal health and well-being, since it mainly affects wild birds, poultry and other animals, including humans, putting the food security and subsistence of those who depend on it at risk.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142684120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Epidemiological and clinical aspects of Guilain-Barré syndrome, 2012-2022]. [吉兰-巴雷综合征的流行病学和临床方面,2012-2022 年]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306747
Coltzinc Hazael Hernández-Jardón, Leora Velásquez-Pérez
{"title":"[Epidemiological and clinical aspects of Guilain-Barré syndrome, 2012-2022].","authors":"Coltzinc Hazael Hernández-Jardón, Leora Velásquez-Pérez","doi":"10.5281/zenodo.13306747","DOIUrl":"10.5281/zenodo.13306747","url":null,"abstract":"<p><strong>Background: </strong>Guillain-Barré syndrome (GBS) is an immune-mediated polyradiculoneuropathy, generally post-infectious, and is the leading cause of acute flaccid paralysis worldwide.</p><p><strong>Objective: </strong>To describe the epidemiological, clinical and behavioral characteristics of Guillain-Barré syndrome.</p><p><strong>Material and methods: </strong>An observational, cross-sectional and descriptive study was carried out. The records of all patients with GBS from 2012-2022 were reviewed, and information on epidemiological and clinical variables was obtained. The incidence was calculated for each of the study years and the trend for the study period using the Pearson correlation coefficient, considering p ≤ 0.05 statistically significant.</p><p><strong>Results: </strong>A total of 477 cases were obtained, 67% were men, among the comorbidities, drug addictions were present in 31% of the cases. Most cases were preceded by a gastrointestinal infectious condition. The most common phenotype was acute motor axonal neuropathy. 29% showed up in summer. A statistically significant tendency to increase was observed (p ≤ 0.05) and a mortality of 2.5% with predominance in the axonal variety.</p><p><strong>Conclusions: </strong>The results of this study cover a relatively long period compared to other reviews, the findings agree with previous studies. GBS showed a statistically significant tendency to increase.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Emerging roles of neutrophils in the prognosis of colorectal cancer]. [中性粒细胞在结直肠癌预后中的新作用]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306792
Alejandra Mantilla, María de Lourdes Ramírez-Ramírez, Antonio Jorge Berlanga-Taylor, Eduardo Vadillo
{"title":"[Emerging roles of neutrophils in the prognosis of colorectal cancer].","authors":"Alejandra Mantilla, María de Lourdes Ramírez-Ramírez, Antonio Jorge Berlanga-Taylor, Eduardo Vadillo","doi":"10.5281/zenodo.13306792","DOIUrl":"10.5281/zenodo.13306792","url":null,"abstract":"<p><p>Colorectal cancer (CRC) is one of the most frequent and lethal cancers in Mexico and the world. It is noteworthy that globally, the incidence of CRC is increasing at a rate of 2% per year in patients younger than 50 years of age. Its early detection, primarily based on colonoscopy screening starting at 45 years of age, is an essential weapon to reduce its mortality. When CRC is detected, the treatment is surgical; however, the pathology reports and biomedical research on the tumor microenvironment may offer new parameters that could serve as prognostic biomarkers. In this respect, the presence or absence of neutrophils associated with neoplastic tissues may indicate their prognostic relevance for the disease. Although this field is still controversial, our recently published evidence suggests that the presence of neutrophils with an anti-tumoral phenotype, particularly at the invasive margin of the colon tumors, could indicate a favorable prognosis. This emerging information suggests that the characterization of immune cells, particularly neutrophils, could contribute to assessing the evolution of CRC and identifying patients at increased risk of recurrences. In this article, we discuss relevant points that should be addressed when interpreting neutrophil-related data in the context of CRC.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Characteristics of melanoma in Mexicans seen at "La Raza" National Medical Center]. [在 "La Raza "国家医疗中心就诊的墨西哥人中黑色素瘤的特征]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306762
Blanca Carlos-Ortega, Ulises Ángeles-Garay, Marian Fernández-Martínez, Guillermo Gómez-Campos, Rodrigo Roldán-Marín
{"title":"[Characteristics of melanoma in Mexicans seen at \"La Raza\" National Medical Center].","authors":"Blanca Carlos-Ortega, Ulises Ángeles-Garay, Marian Fernández-Martínez, Guillermo Gómez-Campos, Rodrigo Roldán-Marín","doi":"10.5281/zenodo.13306762","DOIUrl":"10.5281/zenodo.13306762","url":null,"abstract":"<p><strong>Background: </strong>Melanoma is the third most common type of skin cancer in Mexico and represents 75% of skin cancer deaths. Dermoscopy is a diagnostic tool that increases early detection of melanoma compared to naked eye examination.</p><p><strong>Objective: </strong>The aim of this study was to describe the clinical, dermoscopic and histological characteristics of patients with a confirmed diagnosis of cutaneous melanoma treated at the \"La Raza\" National Medical Center.</p><p><strong>Material and methods: </strong>A retrospective, descriptive and cross-sectional study was carried out from March 1998 to December 2013, with 187 histologically confirmed cases, considering: sex, age, skin phototype, history, topography of the lesion, dermoscopic pattern, metastasis at the time of diagnosis and histological subtype, Breslow index and Clark index, using the chi-square test as a non-parametric statistical method to analyze the data obtained.</p><p><strong>Results: </strong>Most patients had skin phototype III and the most affected location was the lower limb. Clinically, acral lentiginous melanomas and nodular melanomas were the most observed. The most common dermoscopic finding was the multicomponent pattern. Clinically and histologically, the most frequent subtype associated with metastasis was nodular melanoma. Acral lentiginous melanoma was more common among patients without metastasis.</p><p><strong>Conclusions: </strong>Unfortunately, melanoma is still diagnosed in advanced stages in Mexico; for its early recognition, training in the use of dermoscopy and greater awareness about melanoma in the Mexican population must be encouraged.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142684121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Clostridiodes difficile bacteraemia. First mexican case report]. [难辨梭状芽孢杆菌菌血症:墨西哥首例报告]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306825
Iván González-Godínez, Edgar Carrillo-Vázquez, Ana Laura Garduño-Ortíz, Sebastián Enrique Chacón-Hernández, Homero Antonio Hevia-Del Cabrera
{"title":"[Clostridiodes difficile bacteraemia. First mexican case report].","authors":"Iván González-Godínez, Edgar Carrillo-Vázquez, Ana Laura Garduño-Ortíz, Sebastián Enrique Chacón-Hernández, Homero Antonio Hevia-Del Cabrera","doi":"10.5281/zenodo.13306825","DOIUrl":"https://doi.org/10.5281/zenodo.13306825","url":null,"abstract":"<p><strong>Background: </strong>Clostridiodes difficile bacteremia (CDB) develops in less than 1% of all the cases, nonetheless, with a significant increase in mortality. The objective of the present article is to report the first case of CDB in the Mexican population, empathizing with the treatment difficulty derived from the lack of consensus.</p><p><strong>Clinical case: </strong>A 42-year-old female with previous history of chronic thromboembolic pathologies and grade III obesity, develops community acquired atypical pneumonia requiring hospitalization, having parenteral antibiotics. During hospitalization, non severe C. difficile infection was concluded and started treatment with Vancomycin for 10 days. One week later the patient presented to the emergency department at HES CMN SXXI with gastrointestinal symptomatology, mostly epigastric pain, fever and diarrhea. After proper approach, C. difficile was isolated in blood cultures through mass spectrophotometry analysis, for which a 10-day treatment of metronidazole was prescribed with resolution of the infection being discharged afterwards.</p><p><strong>Conclusions: </strong>CDB is an exceptional and lethal clinical condition, mainly seen in patients with previous gastrointestinal diseases. IV Metronidazole demonstrated therapeutic efficacy in this case report and could be a successful and available therapeutic option in Mexican health care units.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Impact of COVID-19 on gallbladder disease: presentation of postponed surgeries]. [COVID-19对胆囊疾病的影响:推迟手术的介绍]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13381474
Milton Alberto Muñoz-Leija, Marion Carolina Áleman-Jiménez, Francisco Daniel Guerrero-Mendivil, Ricardo Xavier Cuellar-Támez, Fernando Alcorta-Núñez, Victor Daniel Cárdenas-Salas, Griselda Luna-Quizihuitl, Edgar Francisco Rodríguez-Bracho, Heliodoro Plata-Álvarez
{"title":"[Impact of COVID-19 on gallbladder disease: presentation of postponed surgeries].","authors":"Milton Alberto Muñoz-Leija, Marion Carolina Áleman-Jiménez, Francisco Daniel Guerrero-Mendivil, Ricardo Xavier Cuellar-Támez, Fernando Alcorta-Núñez, Victor Daniel Cárdenas-Salas, Griselda Luna-Quizihuitl, Edgar Francisco Rodríguez-Bracho, Heliodoro Plata-Álvarez","doi":"10.5281/zenodo.13381474","DOIUrl":"https://doi.org/10.5281/zenodo.13381474","url":null,"abstract":"<p><strong>Introduction: </strong>Since the COVID-19 outbreak escalated to pandemic levels, numerous hospitals deferred elective interventions. Studies reporting the incidence, presentation, severity, and outcomes in the surgical management of biliary diseases differ before, during and after the pandemic.</p><p><strong>Objective: </strong>Evaluate the presentation of biliary pathology by diagnosis and Parkland Grading Scale in patients whose surgeries were postponed due to the pandemic, and who were later surgically intervened.</p><p><strong>Methods: </strong>A retrospective study was conducted. Patients with biliary pathology who had a scheduled cholecystectomy canceled during the pandemic were included. Student's t-test and Chi-Square tests were employed for statistical analysis.</p><p><strong>Results: </strong>A total of 520 patients were evaluated, cholelithiasis was the most common diagnosis in 74.4%. Grade III on the Parkland Grading Scale (PGS) was the most prevalent at 43.7%. Significant differences were observed between genders (p = 0.000) and emergency versus elective surgeries (p = 0.000) in relation to the PGS. Hospitalization duration also exhibited a statistically significant difference between emergency and elective surgeries (p = 0.000).</p><p><strong>Conclusion: </strong>Most patients presented a Grade III on the PGS, reflecting a one-level increase compared to pre-pandemic literature prevalence. More studies are needed to evaluate the real impact of the pandemic on biliary pathology.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Echocardiographic findings after SARS-CoV-2 infection in medical residents without previous cardiopulmonary pathology in a tertiary hospital]. [一家三级医院中既往无心肺病史的医学住院医师感染 SARS-CoV-2 后的超声心动图检查结果]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306709
María Fernanda Rivera-Argumedo, Edgar Bautista-Soto, Ernesto Hernández-Jiménez, Álvaro José Montiel-Jarquín, Arturo García-Galicia, Maricarmen Tapia-Venancio, María Fernanda Rojas-Velasco, Ana Cari Altamirano-Sánchez, Nancy Rosalía Bertado-Ramírez, Adriana Hernández-Carrasco
{"title":"[Echocardiographic findings after SARS-CoV-2 infection in medical residents without previous cardiopulmonary pathology in a tertiary hospital].","authors":"María Fernanda Rivera-Argumedo, Edgar Bautista-Soto, Ernesto Hernández-Jiménez, Álvaro José Montiel-Jarquín, Arturo García-Galicia, Maricarmen Tapia-Venancio, María Fernanda Rojas-Velasco, Ana Cari Altamirano-Sánchez, Nancy Rosalía Bertado-Ramírez, Adriana Hernández-Carrasco","doi":"10.5281/zenodo.13306709","DOIUrl":"https://doi.org/10.5281/zenodo.13306709","url":null,"abstract":"<p><strong>Background: </strong>SARS-CoV-2 disease is associated with a wide spectrum of cardiovascular, renal, and cognitive complications and effects. The most common cardiovascular findings are pericarditis, myocarditis and arrhythmias described in 5-11% of the general population. Specific information on cardiovascular outcomes in healthcare workers in Mexico is lacking.</p><p><strong>Objective: </strong>To determine the echocardiographic findings after SARS-CoV-2 infection in residents at a tertiary care teaching hospital.</p><p><strong>Material and methods: </strong>A prospective, cross-sectional, and selective study was performed. A sample of 62 resident physicians with a diagnosis of COVID-19 was selected from March 2020 to February 2023. Transthoracic echocardiograms were performed, and the findings were described.</p><p><strong>Results: </strong>The main echocardiographic findings were: pericardial refractoriness (90.3%), pericardial effusion (6.5%), abnormal left ventricular mobility (1. 6%), abnormal diastolic function (8.1%), aortic regurgitation (6.5%), mitral regurgitation (19.4%), pulmonary regurgitation (35.5%), tricuspid regurgitation (80.6%), mean LVEF of 65% and PSAP of 23 mmHg.</p><p><strong>Conclusions: </strong>The most relevant echocardiographic findings were refractory pericardium, pericardial effusion, left ventricular diastolic dysfunction, and valvular insufficiency, predominantly in men.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142684103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Depression and anxiety in primary care patients with hemodialysis]. [血液透析初级保健患者的抑郁和焦虑]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306713
Ana Yanzi Arroyo-Montes, Edward Ochoa-Tapia
{"title":"[Depression and anxiety in primary care patients with hemodialysis].","authors":"Ana Yanzi Arroyo-Montes, Edward Ochoa-Tapia","doi":"10.5281/zenodo.13306713","DOIUrl":"https://doi.org/10.5281/zenodo.13306713","url":null,"abstract":"<p><strong>Background: </strong>Depression and anxiety affect with persistent sadness, low mood, fear and loss of interest in daily activities. Therefore, it is important to consider hemodialysis patients with psychological disorders in primary care.</p><p><strong>Objective: </strong>To analyze the presence of depression and anxiety with the Beck inventory in patients with hemodialysis in the Family Medicine Unit No. 1.</p><p><strong>Material and methods: </strong>A cross-sectional, analytical study was carried out with a type of convenience sampling. based on the inclusion criteria all patients on hemodialysis morning-afternoon shift and excluding all who do not wish to participate or intellectual disability, sample of 53 patients. Beck's anxiety and depression inventory instrument was applied, and the Pearson correlation coefficient was used to assess the degree of association.</p><p><strong>Results: </strong>The sex with the greatest presence was male (57%) and the age range is 40-46 years with 22.6%, the relationship of patients with end-stage renal disease (ESRD) presented mild anxiety/depression, while patients with moderate anxiety presented intermittent depression, the level of anxiety was positively correlated with depression and anxiety (p = 0.877).</p><p><strong>Conclusions: </strong>ESRD decreases functional capacity, generating psychological disorders such as depression and anxiety, which is why joint management with psychology or psychiatry must be carried out.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142684123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Sirenomelia: a case report]. [Sirenomelia: a case report]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306810
Christian Emmanuel Rodríguez-Partida, Iván Israel Gutiérrez-Gómez
{"title":"[Sirenomelia: a case report].","authors":"Christian Emmanuel Rodríguez-Partida, Iván Israel Gutiérrez-Gómez","doi":"10.5281/zenodo.13306810","DOIUrl":"10.5281/zenodo.13306810","url":null,"abstract":"<p><p>Sirenomelia is a rare congenital anomaly characterized by fusion of the lower extremities and multiple visceral abnormalities. It usually has a lethal prognosis due to the severity of the associated abnormalities. We present the case of a 26-year-old female patient, in her second pregnancy without associated comorbidities, who was admitted to the Emergency department due to a 26-week pregnancy and anhydramnios. She subsequently underwent an ultrasound in the Maternal Fetal Medicine service, who performed the Sirenomelia diagnosis. It was decided to terminate the pregnancy due to the poor prognosis.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Detection of inborn errors of metabolism: guidelines in Mexico and other countries]. [检测先天性代谢错误:墨西哥和其他国家的指导方针]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306777
Sarahi Guerrero-Barrios, Mariana Chiquillo-Domínguez, Jorge Ayón-Aguilar, Sergio Elihu Rodriguez-Alfaro, Socorro Méndez-Martínez, Máximo Alejandro García-Flores
{"title":"[Detection of inborn errors of metabolism: guidelines in Mexico and other countries].","authors":"Sarahi Guerrero-Barrios, Mariana Chiquillo-Domínguez, Jorge Ayón-Aguilar, Sergio Elihu Rodriguez-Alfaro, Socorro Méndez-Martínez, Máximo Alejandro García-Flores","doi":"10.5281/zenodo.13306777","DOIUrl":"https://doi.org/10.5281/zenodo.13306777","url":null,"abstract":"<p><p>Inborn errors of metabolism (IEM), also known as inherited metabolic disorders, are rare but associated with significant morbidity and mortality. The incidence is variable in all regions, worldwide it ranges from 1 in 569 to 2500 live births (LBI). The objective of this work was to carry out a narrative review to identify the guidelines that guide the detection of EIMs through official sources from various countries. A total of 13 documents were identified, including protocols, books, manuals, programs and 4 official websites for the detection of EIMs. In general, there is variability in the selection of EIMs that are detected, from 4 to 61 EIMs, primary congenital hypothyroidism and pheniceltonuria are the two EIMs that are included in most screening programs, spinal atrophy and severe combined immunodeficiency are detected less frequently, the incidence of each EIM is variable between countries and even between states of the same country, with congenital hypothyroidism being the most common. The guidelines for the selection of EIMs are determined by the internal policies of each country, the incidence and economic resources. There is no universal standard for the detection of EIMs, but they all pursue the same purpose: detection, diagnosis and timely treatment. In parallel, it allows us to estimate with greater precision the frequency of these disorders.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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