Revista medica del Instituto Mexicano del Seguro Social最新文献

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[Inflammatory and clinical markers predicting mortality in neonates under 1500 g]. [炎症和临床指标预测1500克以下新生儿死亡率]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-05-02 DOI: 10.5281/zenodo.15178474
Alma Patricia González, Laura Irandeni Acuña-Cenoz, Martha Daniela Alcázar-Olaiz, Pablo Fabián Estevez-Alemán, Carlos Paque-Bautista, Gloria Patricia Sosa-Bustamante
{"title":"[Inflammatory and clinical markers predicting mortality in neonates under 1500 g].","authors":"Alma Patricia González, Laura Irandeni Acuña-Cenoz, Martha Daniela Alcázar-Olaiz, Pablo Fabián Estevez-Alemán, Carlos Paque-Bautista, Gloria Patricia Sosa-Bustamante","doi":"10.5281/zenodo.15178474","DOIUrl":"https://doi.org/10.5281/zenodo.15178474","url":null,"abstract":"<p><strong>Background: </strong>Early neonatal mortality occurs within 7 days of life. Clinical variables, inflammatory markers and CRIB (Clinical Risk Index for Babies) could be useful to identify mortality risk.</p><p><strong>Objective: </strong>To assess the predictive value of inflammatory and clinical markers for early mortality in preterm newborns (PTNB) < 1500 g.</p><p><strong>Material and methods: </strong>Analytical, retroprospective, observational and cross-sectional study. PTNBs with birth weight < 1500 g were included. Clinical characteristics, CRIB, inflammatory markers and C-reactive protein (CRP) were evaluated at 12 hours of life.</p><p><strong>Results: </strong>248 PTNBs were studied, with a gestational age of 32 weeks (IQR 30-34), weight 1285 g (IQR 1070-1400); 20 died (8.06%). Risk factors for mortality were weight ≤ 1000 g, OR = 24 (7.69-77.96), p < 0.0001; gestational age ≤ 28 weeks, OR = 42 (13.71-128.61), p < 0.0001; invasive ventilation, OR = 44.7 (5.85-340), p < 0.0001. Protective factors were antenatal corticosteroids, OR = 0.15 (0.05-0.39), p = 0.0001, and maternal preeclampsia, OR = 0.13 (0.01-1.02), p = 0.01. CRP, base deficit and birth weight were associated with mortality in the multivariate analysis (intercept = 6.62; SE = 1.85; R2 = 0.60; p = 0.0003). CRP ≥ 2.30 µg/dL showed a sensitivity of 26.32% and a specificity of 97.50% for mortality, AUC = 0.69, p = 0.005.</p><p><strong>Conclusions: </strong>Predictors of early mortality were weight ≤ 1000 g, gestational age ≤ 28 weeks and CRP ≥ 2.30 μg/dL.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6488"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Therapeutic response and monitoring of antibody-mediated renal graft rejection]. [抗体介导的肾移植排斥反应的治疗反应和监测]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-05-02 DOI: 10.5281/zenodo.15178468
Yumar Alfredo Hurtado-Castillo, Juana Alejandra Serrano-Ramírez, José Oscar Juaréz-Sánchez, Itzy Maely Gaytán-Campos
{"title":"[Therapeutic response and monitoring of antibody-mediated renal graft rejection].","authors":"Yumar Alfredo Hurtado-Castillo, Juana Alejandra Serrano-Ramírez, José Oscar Juaréz-Sánchez, Itzy Maely Gaytán-Campos","doi":"10.5281/zenodo.15178468","DOIUrl":"https://doi.org/10.5281/zenodo.15178468","url":null,"abstract":"<p><strong>Background: </strong>Antibody-mediated renal graft rejection is one of the main causes of graft loss. Treatment is based on the removal of circulating antibodies, inhibition of residual antibodies, reduction of their formation, minimization of the alloresponse and terminal complement activation.</p><p><strong>Objective: </strong>To assess the therapeutic response in patients who received intravenous immunoglobulin, plasmapheresis, steroid and rituximab as treatment for antibody-mediated renal rejection.</p><p><strong>Material and methods: </strong>An applicative, prospective study was carried out in hospitalized patients under the care of a nephrology service with a diagnosis of antibody-mediated rejection of the renal graft according to BANFF. 20 patients were included in 1 year, the biopsy was reviewed in an effort to classify the type of antibody-mediated rejection and the response to treatment was evaluated to demonstrate whether there was stabilization or improvement in renal function at 12 months of follow-up.</p><p><strong>Results: </strong>Using the Wilcoxon test, creatinine during the biopsy of the injected and creatinine 12 months after receiving the therapeutic regimen were compared. The Z value was -1.8, with a p = 0.069.</p><p><strong>Conclusions: </strong>There was no difference in terms of stabilization or recovery of renal graft function after 12 months of receiving treatment for antibody-mediated rejection based on steroids, plasma exchanges, immunoglobulin and rituximab.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6636"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Association of serum vitamin D and acute renal graft dysfunction]. [血清维生素D与急性肾移植功能障碍的关系]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-05-02 DOI: 10.5281/zenodo.15178453
Germán Alfonso Landeros-García, Severo Manuel Abraham-Mancilla, José Oscar Juárez-Sánchez, Omar Alfredo Jiménez-García, Martha Alicia Hernández-González
{"title":"[Association of serum vitamin D and acute renal graft dysfunction].","authors":"Germán Alfonso Landeros-García, Severo Manuel Abraham-Mancilla, José Oscar Juárez-Sánchez, Omar Alfredo Jiménez-García, Martha Alicia Hernández-González","doi":"10.5281/zenodo.15178453","DOIUrl":"10.5281/zenodo.15178453","url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease (CKD) is a clinical entity characterized by definitive or non-reversible deterioration of the kidney's architecture and/or its functional status. Renal transplantation is the treatment of choice for CKD. New pharmacological therapies have been investigated with the aim of reducing the risk of renal graft rejection; an example of this is vitamin D. However, international evidence presents mixed results.</p><p><strong>Objective: </strong>To evaluate the relationship between serum vitamin D levels and the prevalence of acute renal graft dysfunction in renal transplant patients.</p><p><strong>Material and methods: </strong>A prospective, observational and comparative study was carried out with a population of patients who underwent renal transplantation. The patients were classified into 2 groups: group 1: patients with acute graft dysfunction, and group 2, those without acute graft dysfunction.</p><p><strong>Results: </strong>A statistically significant relationship was found between acute renal graft dysfunction and serum vitamin D levels (p = 0.003). All other characteristics did not show a statistically significant relationship with acute renal graft dysfunction.</p><p><strong>Conclusions: </strong>Low 25-hydroxyvitamin D levels showed a statistically significant association with acute renal graft dysfunction.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6448"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144033305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cognitive impairment in hearing impaired patients compared to normal hearing patients]. [听力受损患者与正常听力患者的认知障碍比较]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-05-02 DOI: 10.5281/zenodo.15178442
Andrea Judith Del Ángel-González, María de Lourdes Liliana de la Rosa-Solis, María Cruz Leal-Reyes
{"title":"[Cognitive impairment in hearing impaired patients compared to normal hearing patients].","authors":"Andrea Judith Del Ángel-González, María de Lourdes Liliana de la Rosa-Solis, María Cruz Leal-Reyes","doi":"10.5281/zenodo.15178442","DOIUrl":"10.5281/zenodo.15178442","url":null,"abstract":"<p><strong>Background: </strong>Hearing loss affects 360 million people worldwide and it is linked to cognitive impairment, which is the main precursor of dementia. Hearing loss is the major modifiable risk factor for cognitive impairment. This study examines the relationship between severe/profound hearing loss and cognitive impairment in people aged 50 to 65 years.</p><p><strong>Objective: </strong>To determine whether severe/profound hearing loss accelerates the development of cognitive impairment in patients with this condition compared to those with normal hearing or mild hearing loss. Material and methods: Analytical cross-sectional study conducted in 254 patients. Degrees of hearing loss were assessed by tonal audiometry using the World Health Organization (WHO) criteria, and the degree of cognitive impairment with the Montreal Cognitive Assessment (MoCA) test. The variables analyzed included age, sex, schooling and socioeconomic level.</p><p><strong>Results: </strong>82.8% of patients with severe/profound hearing loss had cognitive impairment, compared to 17.2% of those with normal hearing (p < 0.001), demonstrating a highly significant association between hearing loss and cognitive impairment.</p><p><strong>Conclusions: </strong>Patients with severe/profound hearing loss have greater cognitive impairment than those with normal hearing. Early diagnosis and treatment, such as the use of hearing aids, is key to prevent cognitive impairment and improve quality of life.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6509"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comment on the article "Hand strength and high blood pressure, a case-control study"]. [对文章《手部力量与高血压,一项病例对照研究》的评论]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-05-02 DOI: 10.5281/zenodo.15178506
Samuel Saldaña-Galicia
{"title":"[Comment on the article \"Hand strength and high blood pressure, a case-control study\"].","authors":"Samuel Saldaña-Galicia","doi":"10.5281/zenodo.15178506","DOIUrl":"https://doi.org/10.5281/zenodo.15178506","url":null,"abstract":"<p><p>Hand grip strength has been widely used in various areas of medicine as an indicator of sarcopenia, nutritional status, risk of cognitive diseases, chronic degenerative diseases and as a predictor of mortality. Several studies have evaluated the relationship between hand grip strength and blood pressure, even though the results have not been conclusive because there are several proven factors that influence hand strength. Therefore, it is relevant to evaluate this relationship in the Mexican population since there are few studies in this field.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6348"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Regional mesenteric oxygen saturation during blood transfusion in premature neonates]. [早产儿输血时肠系膜局部氧饱和度]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-05-02 DOI: 10.5281/zenodo.15178476
González Alma Patricia, Miriam Anaya-Solorzano, Luis Enrique Hernández-Díaz, Estefanía Calderón-Ambriz, Víctor Darío López-Flores, Gloria Patricia Sosa-Bustamante, Carlos Paque-Bautista
{"title":"[Regional mesenteric oxygen saturation during blood transfusion in premature neonates].","authors":"González Alma Patricia, Miriam Anaya-Solorzano, Luis Enrique Hernández-Díaz, Estefanía Calderón-Ambriz, Víctor Darío López-Flores, Gloria Patricia Sosa-Bustamante, Carlos Paque-Bautista","doi":"10.5281/zenodo.15178476","DOIUrl":"https://doi.org/10.5281/zenodo.15178476","url":null,"abstract":"<p><strong>Background: </strong>Neonatal anemia (NA) in premature newborns (PTNB) is common and transfusion is one of the treatments of choice; however, it has been associated with the development of necrotizing enterocolitis (NEC).</p><p><strong>Objective: </strong>To compare regional oxygen saturation (rSO2) and fraction of tissue oxygen excretion (FTOE) at baseline, during and at the end of transfusion in PTNBs with anemia.</p><p><strong>Material and methods: </strong>Prospective, observational, longitudinal, and analytical study. PTNBs of 28-36 weeks of gestational age (WGA) admitted to a Neonatal Intensive Care Unit (NICU) and with transfusion criteria of Canadian Blood Services were included. rSO2 was measured one hour before, during and up to one hour after transfusion.</p><p><strong>Results: </strong>20 PTNBs were analyzed, 3 (15%) girls and 17 (85%) boys, aged 33 WGA (IQR 28-36), postnatal age 31 days (IQR 15-50), and weight of 1815 g (IQR 1385-2520). The rSO2 values before, during and after erythrocyte transfusion were 45.5% (IQR 38.25-60.25), 53.3% (IQR 44.25-64.0) and 53.5% (IQR 50.0-64.25), respectively, F = 5.76, p = 0.006, power = 0.83, DF = 2; FTOE values were 0.50 (IQR 0.31-0.56), 0.42 (IQR 0.30-0.50), and 0.39 (IQR 0.27-0.45), respectively, F = 3.53, p = 0.03, power = 0.62, DF = 2.</p><p><strong>Conclusion: </strong>Mesenteric rSO2 measurements increased and FTOE decreased gradually before, during and after erythrocyte transfusion, without showing correlation with pretransfusion hemoglobin.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6640"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[ICT in the evaluation of the quality of medical care]. [信通技术在医疗保健质量评价中的应用]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-03-03 DOI: 10.5281/zenodo.14901762
Salvador González-Rodríguez, Rodolfo Rivas-Ruiz, Carmen Josephine Espinosa-Rafful, Mónica Alejandra Montano-López, Alfredo Robles-Rodríguez, Rosana Pelayo-Camacho, Laura Cecilia Bonifaz-Alfonzo, Luisa Alejandra Guadalupe Obrador-Garrido Cuesta
{"title":"[ICT in the evaluation of the quality of medical care].","authors":"Salvador González-Rodríguez, Rodolfo Rivas-Ruiz, Carmen Josephine Espinosa-Rafful, Mónica Alejandra Montano-López, Alfredo Robles-Rodríguez, Rosana Pelayo-Camacho, Laura Cecilia Bonifaz-Alfonzo, Luisa Alejandra Guadalupe Obrador-Garrido Cuesta","doi":"10.5281/zenodo.14901762","DOIUrl":"https://doi.org/10.5281/zenodo.14901762","url":null,"abstract":"<p><strong>Background: </strong>The Virtual Verification Application (VVA) was developed as an information and communication technology with the potential to support the formative aspect of evaluation, reduce costs, improve productivity, and provide results and feedback immediately.</p><p><strong>Objective: </strong>To determine the performance of the VVA in an experimental and controlled environment in the evaluation of processes and medical programs.</p><p><strong>Materials and methods: </strong>A process study was conducted comparing the VVA in four controlled clinical environments: Outpatient Consultation, Emergency, Operating Room, and Hospitalization, within the Simulation Center, modifying the conditions of each scenario. Additionally, the results of virtual (VV) and in-person (IP) evaluations conducted by both experts and novices in each environment and scenario were compared. The Bland-Altman method was used, and median differences were evaluated. The costs of both evaluations were also compared.</p><p><strong>Results: </strong>No statistically significant differences were found between scenarios (p = 0.795) or by experience (p = 0.819). In the Outpatient Consultation scenario, the difference was 0.58% (95% CI: -2.45, 1.29%); in Emergency, -0.9% (95% CI: -2.84, 1.04%); in the Operating Room, 0.19% (95% CI: -1.98, 2.36%); and in Hospitalization, there was no difference (0%, 95% CI: -7.37, 7.37%). The cost of the IP was 9.3 times higher than that of the VV.</p><p><strong>Conclusions: </strong>The VVA and the IP evaluations have similar performance, with a significant reduction in costs. Therefore, it is a useful tool for evaluation and for improving the quality of medical care.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 2","pages":"e6209"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12048168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Answer to "Comment on the article: "Diagnostic performance of the FINDRISC questionnaire to identify insulin resistance in adults""]. [对“FINDRISC问卷对成人胰岛素抵抗的诊断性能”一文的评论]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-03-03 DOI: 10.5281/zenodo.14616836
Yuline Varela-Vega, Ivonne Analí Roy-García, Marcela Pérez-Rodríguez, Lubia Velázquez-López
{"title":"[Answer to \"Comment on the article: \"Diagnostic performance of the FINDRISC questionnaire to identify insulin resistance in adults\"\"].","authors":"Yuline Varela-Vega, Ivonne Analí Roy-García, Marcela Pérez-Rodríguez, Lubia Velázquez-López","doi":"10.5281/zenodo.14616836","DOIUrl":"https://doi.org/10.5281/zenodo.14616836","url":null,"abstract":"<p><p>The FINDRISC instrument has been established as a screening tool to determine the risk of developing type 2 diabetes (T2D) at 10 years. However, the established cut-off points were based on a population with a low prevalence of the disease, unlike the Mexican population in which, based on the latest ENSANUT 2022 report, the global prevalence of T2D is 18.3%. Based on this, the need arose to establish a cut-off point to identify the presence of insulin resistance in this population using the FINDRISC instrument. And, in this way, identify the population one step before the development of T2D.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 2","pages":"e5034"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Colitis cystica profunda induced by radiation 27 years later. Case report]. [27年后放射引起的深囊性结肠炎。病例报告)。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-03-03 DOI: 10.5281/zenodo.14617196
José Gustavo García-Acosta, Erika Guadalupe Castañeda-Ángeles
{"title":"[Colitis cystica profunda induced by radiation 27 years later. Case report].","authors":"José Gustavo García-Acosta, Erika Guadalupe Castañeda-Ángeles","doi":"10.5281/zenodo.14617196","DOIUrl":"https://doi.org/10.5281/zenodo.14617196","url":null,"abstract":"<p><strong>Background: </strong>Colitis cystica profunda is a rare and infrequent benign lesion of the colon and rectum-sigmoid colon. Histologically, it is characterized by glandular cystic dilatation with mucin production and extension through the colonic wall, penetrating the muscularis mucosae, submucosa, and even the muscularis propria. We report a case of colitis cystica profunda that occurred in a radiation-induced colonic stenosis.</p><p><strong>Clinical case: </strong>A 66-year-old woman with a history of stage IA2 squamous cell carcinoma of the cervix, treated with conization in addition to simultaneous chemotherapy and radiotherapy. External beam radiation with cobalt60 was administered at specific doses. 27 years later, she presented diarrheal stools approximately 7 times with abdominal distension. On physical examination, a tumor was found in the sigmoid colon; she was referred to a third-level hospital; a colostomy in the left transverse loop and sigmoidectomy were performed. In the pathological analysis, a Rectosigmoidectomy product was received and a zone of stenosis with shiny mucosa and thickening of the wall was found. Microscopically, submucosal cysts filled with mucin of variable size were found, covered by a layer of epithelium without atypia that infiltrated the colonic wall.</p><p><strong>Conclusions: </strong>Colitis cystica profunda is a benign non-neoplastic disease. Knowledge of this pathological entity associated with a history of radiation is important since there are few cases reported in the literature.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 2","pages":"e6332"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Surgical outcomes in patients with esophageal cancer in a third level center]. [三级中心食管癌手术疗效分析]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-03-03 DOI: 10.5281/zenodo.14616876
Edgar Joaquín Cortes-Torres, Miguel Angel Reyna-Silva, Alejandro González-Ojeda, Clotilde Fuentes-Orozco, Gabino Cervantes-Guevara, Ana Guadalupe Sánchez-Luna, Kathia Dayana Morfín-Meza, Andrea Garcia
{"title":"[Surgical outcomes in patients with esophageal cancer in a third level center].","authors":"Edgar Joaquín Cortes-Torres, Miguel Angel Reyna-Silva, Alejandro González-Ojeda, Clotilde Fuentes-Orozco, Gabino Cervantes-Guevara, Ana Guadalupe Sánchez-Luna, Kathia Dayana Morfín-Meza, Andrea Garcia","doi":"10.5281/zenodo.14616876","DOIUrl":"10.5281/zenodo.14616876","url":null,"abstract":"<p><strong>Background: </strong>Esophageal cancer is the seventh most diagnosed neoplasm, with a higher prevalence in men. Tobacco and alcohol consumption, gastroesophageal reflux disease, and Barrett's esophagus are associated with the development of adenocarcinoma and squamous cell carcinoma.</p><p><strong>Objective: </strong>To identify the clinical profile in patients with esophageal cancer at a tertiary care center.</p><p><strong>Materials and methods: </strong>A cross-sectional, observational study. Patients with esophageal cancer were evaluated between January 2014 and July 2019. The study variables included sex, age, histological type, postoperative complications, mortality, and survival.</p><p><strong>Results: </strong>A total of 34 patients were evaluated, with a mean age of 61.8 ± 8.9 years. 88.2% were men. Tumor location was as follows: lower third (76.5%), middle third (17.6%), and upper third (5.9%). The most common histological types were adenocarcinoma (67.6%) and squamous cell carcinoma (32.4%). Symptoms included: dysphagia in 34 (100%) and epigastric pain in 20 (58.8%). The types of surgeries performed were: transhiatal in 15 (44.1%), palliative in 15 (44.1%), Ivor Lewis in 1 (2.9%), and McKeown in 1 (2.9%). Postoperative complications included: respiratory (29.4%), anastomotic leak (20.6%), sepsis (11.8%), and fistula (2.9%). Mortality was 13 (38.2%) patients, and survival at 22 months was 22%.</p><p><strong>Conclusions: </strong>Our study showed a higher prevalence of esophageal cancer in men over 60 years old with adenocarcinoma localized in the lower third of the esophagus. Despite chemotherapy treatment, patient survival remains poor due to late diagnosis in advanced stages of the disease, which limits tumor resectability and operability, leading to increased mortality.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 2","pages":"e6323"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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