Revista medica del Instituto Mexicano del Seguro Social最新文献_第10页

[Clinician and researcher at the time. Is it possible?] [当时的临床医生和研究人员。有可能吗？]

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2023-10-02 DOI: 10.5281/zenodo.8319763

Jorge Moreno-Palacios, Eduardo Serrano-Brambila, Ricardo Berea-Baltierra

引用次数: 0

[Comment on article: "Laboratories as predictors of length of hospital stay in patients with pneumonia"]. [评论文章：“实验室作为肺炎患者住院时间的预测因素”]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2023-10-02 DOI: 10.5281/zenodo.8319834

Esmeralda Campos-Aguirre, Rodolfo Rivas-Ruiz, Gamaliel Benítez-Arvizu

引用次数: 0

[Risk factors associated with cognitive impairment in aged: Cross-sectional study]. [与老年人认知障碍相关的危险因素：横断面研究]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2023-10-02 DOI: 10.5281/zenodo.8319815

Moises Moreno-Noguez, Juan Castillo-Cruz, Luis Rey García-Cortés, Haynna Raquel Gómez-Hernández

{"title":"[Risk factors associated with cognitive impairment in aged: Cross-sectional study].","authors":"Moises Moreno-Noguez, Juan Castillo-Cruz, Luis Rey García-Cortés, Haynna Raquel Gómez-Hernández","doi":"10.5281/zenodo.8319815","DOIUrl":"10.5281/zenodo.8319815","url":null,"abstract":"Background: With the increase in life expectancy, conditions related to older age have increased in incidence, one of these pathologies is Cognitive Impairment (CI), which has a prevalence of up to 28%, conditions that increase the presence of CI are known. However, there is controversy about the factors that increase the risk of CI.Objective: To determine the factors associated with cognitive impairment in older adults.Material and methods: We conducted a cross-sectional, analytical, observational, retroprolective study that included adults ≥65 years of age, with no history of cerebral vascular event, cranioencephalic trauma. Demographic factors were analyzed, CI was assessed with the Mini Mental State Examination test. For statistical analysis we used Odds Ratio (OR) and 95% confidence interval (95% CI) for each factor and multiple logistic regression as multivariate analysis.Results: 420 older adults were included, 61% were women, 32.6% with age >75 years, 84.5% with schooling <9 years, in the multiple logistic regression the following were independent factors for the presence of mild CI: dependence on basic activities of daily living (ADLs) with OR 5.88, absence of cognitive stimulation RM 4.50, age >75 years OR 2.92, polypharmacy OR 2.16, uncontrolled blood pressure OR 1.92.Conclusion: ADLs dependence, absence of cognitive stimulation, age >75 years, polypharmacy and uncontrolled blood pressure are risk factors associated with CI in older adults.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10732693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71490653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Risk factors associated with lethality on patients with central cord syndrome]. [与中枢脊髓综合征患者致死相关的危险因素]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2023-10-02 DOI: 10.5281/zenodo.8319828

Patricio Dabdoub-González, Edgar Abel Márquez-García, Juan Gerardo Reyes-García, Jorge Arturo Cabrera-Escamilla, David Fernando Servín-Carmona, Víctor Hugo Tejerina-Gorena, Cristóbal Herrera-Palacios, Elvia Janike Rodríguez-Córdoba

{"title":"[Risk factors associated with lethality on patients with central cord syndrome].","authors":"Patricio Dabdoub-González, Edgar Abel Márquez-García, Juan Gerardo Reyes-García, Jorge Arturo Cabrera-Escamilla, David Fernando Servín-Carmona, Víctor Hugo Tejerina-Gorena, Cristóbal Herrera-Palacios, Elvia Janike Rodríguez-Córdoba","doi":"10.5281/zenodo.8319828","DOIUrl":"10.5281/zenodo.8319828","url":null,"abstract":"Background: Central Cord Syndrome is the most common incomplete spinal cord injury, and it represents 9% of all spinal injuries of the adult.Objective: to determine the risk factors associated with lethality or/and mechanical ventilation (MV) in patients with Central Cord Syndrome (CCS).Material and methods: upon a retrospective cohort with patients with posttraumatic CCS we evaluated at the time of emergency admission and until the hospital discharge. The dependent variable was dead or MV. We calculated incidence, relative risk (RR) with CI95% and a multivariate model for the association of statistically significant variables by means of a risk coefficient model upon the variables that evidenciated tendencies towards risk.Results: From 101 patients with CCS, 85.1% with a severe medullary canal stenosis and 9.9% required MV; the mortality was 13.9%. The only risk factor associated with dead was the use of MV with an RR of 3.6 (CI95% 1.4-9.5); the risk with tendencies towards MV was being older than 60 RR 5.4 (CI95% 0.6-44.2). Other factors demonstrated a tendency towards mortality, but they were not statistically significant.Conclusions: MV is a risk factor associated with mortality, other factors evidenciated tendencies towards mortality; being older than 60, hypertension, diabetes mellitus, narrow spinal canal, more than 20 days of hospital stay and being intervened farther than 10 days from the accident. The incidence of mortality in our sample is greater than thus reported previously on other international articles. To know and identify these and other factors will let us identify patients with a greater risk of complications.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10746331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71490654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Characteristics of patients with systemic sclerosis who develop interstitial lung disease]. [发生间质性肺病的系统性硬化症患者的特征]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2023-10-02 DOI: 10.5281/zenodo.8383951

Luis Daniel Fajardo-Hermosillo, Mario César Ocampo-Torres, Juan Rodríguez-Silverio

{"title":"[Characteristics of patients with systemic sclerosis who develop interstitial lung disease].","authors":"Luis Daniel Fajardo-Hermosillo, Mario César Ocampo-Torres, Juan Rodríguez-Silverio","doi":"10.5281/zenodo.8383951","DOIUrl":"10.5281/zenodo.8383951","url":null,"abstract":"Background: Systemic sclerosis associated-interstitial lung disease (SSc-ILD) show a high mortality. The factors associated SSc-ILD have shown variability in different populations. There are few studies in Mexican mestizos.Objective: To analyze the epidemiological, clinical and paraclinical factors associated with SSc-ILD.Material and methods: Cross-sectional study, where patients > 18 years of age with a diagnosis of SSc according to EULAR/ACR 2013 criteria and diagnosis of ILD by forced vital capacity (FVC) < 70% and > 5% of affected lung area on tomography were included. The strength of association of the factors for ILD was measured by odds ratio (OR) with 95% confidence intervals (95% CI). The significant variables were analyzed by multiple logistic regression with adjustment.Results: Of the 80 patients with SSc, 38 (47.5%) had ILD. Risk factors such as smoking, higher activity index, lower FVC, anti-topoisomerase I antibodies, and protective factors such as a limited SSc, early capillaroscopic pattern, and anti-centromere antibodies (ACA) were associated with ILD. In the multivariate analysis, a higher activity index with OR 4.17, (95% CI 2.01-8.65) persisted as a risk factor, while ACA with OR 0.17, (95% CI 0.03-0.85) persisted as a protective factor associated with SSc-ILD.Conclusions: A higher index of activity and ACA persisted as factors associated with SSc-ILD.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10730132/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71490730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Efficacy and safety of atorvastatin in major cardiovascular events: Meta-analysis]. 【阿托伐他汀治疗重大心血管事件的疗效和安全性：荟萃分析】。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2023-10-02 DOI: 10.5281/zenodo.8319748

Víctor Eder Villegas-Quintero, Rodolfo Rivas-Ruíz, Alexis Alejandro García-Rivero, Pedro Rivera-Lara, Nelly Berenice González-Tovar

{"title":"[Efficacy and safety of atorvastatin in major cardiovascular events: Meta-analysis].","authors":"Víctor Eder Villegas-Quintero, Rodolfo Rivas-Ruíz, Alexis Alejandro García-Rivero, Pedro Rivera-Lara, Nelly Berenice González-Tovar","doi":"10.5281/zenodo.8319748","DOIUrl":"10.5281/zenodo.8319748","url":null,"abstract":"Introduction: Atorvastatin has been used in the management of dyslipidemia and little is known about the efficacy and safety of high-dose atorvastatin administration for secondary prevention of Major Cardiovascular Events (MACE).Objective: To evaluate the impact of high-dose atorvastatin on secondary prevention of MACE and adverse events.Material and methods: A systematic review and meta-analysis of Pubmed, Embase, Bireme and Cochrane Library Plus databases was performed, with a time scope from 1990 to July 2022. Six randomized clinical trials were included with a total of 29,333 patients who were treated with 80 mg, 10 mg or placebo doses of Atorvastatin where the main outcomes evaluated were Major Cardiovascular Events (MACE), mortality and treatment safety.Results: In the comparative study between the use of Atorvastatin 80 mg and other therapies, a relative risk (RR) of 0.8 (95%CI 0.69-0.92) was found, representing a 20% reduction in risk (RRR) and a number needed to treat (NNT) of 30-55. In the analysis of adverse effects, an RR of 2.37 (95% CI 0.86-6.53) and a number needed to harm (NNH) of 14-19 were observed. The use of 80 mg atorvastatin is associated with similar adverse events at lower doses.Conclusions: The use of atorvastatin 80 mg is effective in the secondary prevention of Major Cardiovascular Event (MACE). The drug has adverse events that should be taken into account in secondary prevention.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10735271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71490734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The track of the clinical researcher]. [临床研究人员的轨迹]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2023-10-02 DOI: 10.5281/zenodo.8319733

Rodolfo Rivas-Ruiz

引用次数: 0

[Adverse effect incidence of Pfizer/BioNTech COVID-19 vaccine: Retrospective cohort study]. [辉瑞/BioNTech新冠疫苗不良反应发生率:回顾性队列研究]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2023-09-18

Ana Carolina Martínez-Roa, Lázaro Labra-Rubio, Isette Yunue Landeros-Navarro

{"title":"[Adverse effect incidence of Pfizer/BioNTech COVID-19 vaccine: Retrospective cohort study].","authors":"Ana Carolina Martínez-Roa, Lázaro Labra-Rubio, Isette Yunue Landeros-Navarro","doi":"","DOIUrl":"","url":null,"abstract":"Background: Coronavirus SARS-CoV-2 has been the cause of multiple hospitalizations due to respiratory distress, pneumonia, multi-organic failure and death in all the world. The BioNTech/Pfizer lab was the first to get the approval from the Food and Drug Administration (FDA) for vaccine application, beginning with health workers. However, there are a few studies about adverse effects after applying the COVID-19 vaccine.Objective: To assess the presence and time of onset of adverse effects produced by the COVID-19 vaccine.Material and methods: A retrospective cohort study was carried out, including medical residents from the Hospital de Especialidades No. 1 (Specialties Hospital No. 1) from the Bajío National Medical Center, who received two doses of Pfizer-BioNTech vaccine and decided to participate voluntarily. We obtained the information by a self-assessment tool sent via email. All adverse effects were collected emphasizing those described in the literature.Results: A total of 101 medical residents were included. It was observed that 55.54% presented adverse effects after the first dose, which appeared in the first 24 hours after the vaccine was administered. After the second dose, 54.5% presented symptomatology, 41.6% during first 24 hours after the vaccine was administered.Conclusions: It was observed symptomatology after applying the complete series (two doses) of BioNTech/Pfizer; however, there were mild and of short duration.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10761190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138447676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Inflammatory indexes and their association with the severity of preeclampsia]. [炎症指数及其与子痫前期严重程度的关系]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2023-09-18

Emma Thalia Conde-Rico, Jaime Naves-Sánchez, Alma Patricia González, José Luis Felipe Luna-Anguiano, Carlos Paque-Bautista, Gloria Patricia Sosa-Bustamante

{"title":"[Inflammatory indexes and their association with the severity of preeclampsia].","authors":"Emma Thalia Conde-Rico, Jaime Naves-Sánchez, Alma Patricia González, José Luis Felipe Luna-Anguiano, Carlos Paque-Bautista, Gloria Patricia Sosa-Bustamante","doi":"","DOIUrl":"","url":null,"abstract":"Background: Recent studies have confirmed the relationship between some inflammatory indexes and preeclampsia (PE); however, they have not been analyzed in PE with and without severity criteria.Objective: To know the association between inflammatory indexes and the severity of PE.Material and methods: Analytical cross-sectional prolective study. Pregnant patients were included, divided into group 1 (PE without severity criteria); group 2 (PE with severity criteria); group 3 (normotensive pregnant women). Records were reviewed and inflammatory indexes [(neutrophil-lymphocyte ratio [NLR], platelet-lymphocyte ratio [PLR], lymphocyte-monocyte ratio [LMR] and systemic immune index [SII]) were calculated.Results: 240 patients were analyzed, 80 per group; age 28 (IQR 27-29) years. A significant difference was observed between group 1, group 2 and group 3, NLR 3.29 (IQR 2.82-3.69), 3.59 (IQR 2.83-4.2) and 3.42 (IQR 3.17-3.92), respectively, p = 0.02; PLR 121.59 (IQR 103.78-132), 108.32 (IQR 92.96-127.43) 136 (IQR 115.18-157.56), respectively, p = 0.01; LMR and SII showed no difference between the groups. LMR made possible to distinguish PE with and without severity criteria, cut-off point of ≥ 3.20, sensitivity 56%, specificity 56%, AUC 0.56, p = 0.01, and cut-off point ≥ 3.24, sensitivity 58%, specificity 58%, AUC 0.57, p = 0.04, respectively; the LMR ≥ 3.24 was associated with PE without severity criteria (OR 2.02 [95%CI 1.08-3.80], p = 0.03).Conclusions: The MLR was the only inflammatory index analyzed that was associated with the presence of PE without severity data. No inflammatory index was associated with PE with severity data.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138447684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Prenatal diagnosis of placenta acretta by ultrasound and its histopathological association]. [胎儿胎盘的超声诊断及其组织病理学关联]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2023-09-18

Braulio César Zapien-Terrones, Jaime Naves-Sánchez, Gloria Patricia Sosa-Bustamante, Alma Patricia González, Carlos Paque-Bautista, José Luis Felipe Luna-Anguiano, Catalina Peralta-Cortázar

{"title":"[Prenatal diagnosis of placenta acretta by ultrasound and its histopathological association].","authors":"Braulio César Zapien-Terrones, Jaime Naves-Sánchez, Gloria Patricia Sosa-Bustamante, Alma Patricia González, Carlos Paque-Bautista, José Luis Felipe Luna-Anguiano, Catalina Peralta-Cortázar","doi":"","DOIUrl":"","url":null,"abstract":"Background: Anomalous adhesions of the placenta, known as placenta accreta and its variants, are the cause of obstetric hemorrhages that put the pregnant woman at risk. Accretism is strongly associated with a history of uterine surgery (cesarean section, myomectomy, curettage), as well as ultrasonographic signs, such as the presence and size of placental lacunae, loss of the placenta/bladder interface, location on the anterior face of the placenta, and presence of Doppler flow; these markers can be assessed by prenatal ultrasound.Objective: To analyze the association of prenatal diagnosis of placenta accreta by ultrasound with the histopathological result using the Tovbin index.Material and methods: Observational, cross-sectional and analytical study. 63 patients who had placenta accreta data by ultrasound measured with the Tovbin index and by means of the histopathological result obtained from the platform of the Mexican Institute for Social Security (IMSS) were included. The association between the two studies with the presence of placenta accreta was analyzed.Results: 63 patients were analyzed; the Tovbin index was positive in 89% of the patients with a diagnosis of placenta accreta confirmed by histopathology. Both the Tovbin index and the histopathology report showed a statistically significant association with a p value of 0.04 for the diagnosis of placenta accreta.Conclusion: The Tovbin index as an ultrasonographic prenatal diagnosis of placenta accreta has a statistically significant association with histopathology diagnosis.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10761192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138447688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0