Revista medica del Instituto Mexicano del Seguro Social最新文献

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[Impact of COVID-19 on gallbladder disease: presentation of postponed surgeries]. [COVID-19对胆囊疾病的影响:推迟手术的介绍]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13381474
Milton Alberto Muñoz-Leija, Marion Carolina Áleman-Jiménez, Francisco Daniel Guerrero-Mendivil, Ricardo Xavier Cuellar-Támez, Fernando Alcorta-Núñez, Victor Daniel Cárdenas-Salas, Griselda Luna-Quizihuitl, Edgar Francisco Rodríguez-Bracho, Heliodoro Plata-Álvarez
{"title":"[Impact of COVID-19 on gallbladder disease: presentation of postponed surgeries].","authors":"Milton Alberto Muñoz-Leija, Marion Carolina Áleman-Jiménez, Francisco Daniel Guerrero-Mendivil, Ricardo Xavier Cuellar-Támez, Fernando Alcorta-Núñez, Victor Daniel Cárdenas-Salas, Griselda Luna-Quizihuitl, Edgar Francisco Rodríguez-Bracho, Heliodoro Plata-Álvarez","doi":"10.5281/zenodo.13381474","DOIUrl":"https://doi.org/10.5281/zenodo.13381474","url":null,"abstract":"<p><strong>Introduction: </strong>Since the COVID-19 outbreak escalated to pandemic levels, numerous hospitals deferred elective interventions. Studies reporting the incidence, presentation, severity, and outcomes in the surgical management of biliary diseases differ before, during and after the pandemic.</p><p><strong>Objective: </strong>Evaluate the presentation of biliary pathology by diagnosis and Parkland Grading Scale in patients whose surgeries were postponed due to the pandemic, and who were later surgically intervened.</p><p><strong>Methods: </strong>A retrospective study was conducted. Patients with biliary pathology who had a scheduled cholecystectomy canceled during the pandemic were included. Student's t-test and Chi-Square tests were employed for statistical analysis.</p><p><strong>Results: </strong>A total of 520 patients were evaluated, cholelithiasis was the most common diagnosis in 74.4%. Grade III on the Parkland Grading Scale (PGS) was the most prevalent at 43.7%. Significant differences were observed between genders (p = 0.000) and emergency versus elective surgeries (p = 0.000) in relation to the PGS. Hospitalization duration also exhibited a statistically significant difference between emergency and elective surgeries (p = 0.000).</p><p><strong>Conclusion: </strong>Most patients presented a Grade III on the PGS, reflecting a one-level increase compared to pre-pandemic literature prevalence. More studies are needed to evaluate the real impact of the pandemic on biliary pathology.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Echocardiographic findings after SARS-CoV-2 infection in medical residents without previous cardiopulmonary pathology in a tertiary hospital]. [一家三级医院中既往无心肺病史的医学住院医师感染 SARS-CoV-2 后的超声心动图检查结果]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306709
María Fernanda Rivera-Argumedo, Edgar Bautista-Soto, Ernesto Hernández-Jiménez, Álvaro José Montiel-Jarquín, Arturo García-Galicia, Maricarmen Tapia-Venancio, María Fernanda Rojas-Velasco, Ana Cari Altamirano-Sánchez, Nancy Rosalía Bertado-Ramírez, Adriana Hernández-Carrasco
{"title":"[Echocardiographic findings after SARS-CoV-2 infection in medical residents without previous cardiopulmonary pathology in a tertiary hospital].","authors":"María Fernanda Rivera-Argumedo, Edgar Bautista-Soto, Ernesto Hernández-Jiménez, Álvaro José Montiel-Jarquín, Arturo García-Galicia, Maricarmen Tapia-Venancio, María Fernanda Rojas-Velasco, Ana Cari Altamirano-Sánchez, Nancy Rosalía Bertado-Ramírez, Adriana Hernández-Carrasco","doi":"10.5281/zenodo.13306709","DOIUrl":"https://doi.org/10.5281/zenodo.13306709","url":null,"abstract":"<p><strong>Background: </strong>SARS-CoV-2 disease is associated with a wide spectrum of cardiovascular, renal, and cognitive complications and effects. The most common cardiovascular findings are pericarditis, myocarditis and arrhythmias described in 5-11% of the general population. Specific information on cardiovascular outcomes in healthcare workers in Mexico is lacking.</p><p><strong>Objective: </strong>To determine the echocardiographic findings after SARS-CoV-2 infection in residents at a tertiary care teaching hospital.</p><p><strong>Material and methods: </strong>A prospective, cross-sectional, and selective study was performed. A sample of 62 resident physicians with a diagnosis of COVID-19 was selected from March 2020 to February 2023. Transthoracic echocardiograms were performed, and the findings were described.</p><p><strong>Results: </strong>The main echocardiographic findings were: pericardial refractoriness (90.3%), pericardial effusion (6.5%), abnormal left ventricular mobility (1. 6%), abnormal diastolic function (8.1%), aortic regurgitation (6.5%), mitral regurgitation (19.4%), pulmonary regurgitation (35.5%), tricuspid regurgitation (80.6%), mean LVEF of 65% and PSAP of 23 mmHg.</p><p><strong>Conclusions: </strong>The most relevant echocardiographic findings were refractory pericardium, pericardial effusion, left ventricular diastolic dysfunction, and valvular insufficiency, predominantly in men.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142684103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Depression and anxiety in primary care patients with hemodialysis]. [血液透析初级保健患者的抑郁和焦虑]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306713
Ana Yanzi Arroyo-Montes, Edward Ochoa-Tapia
{"title":"[Depression and anxiety in primary care patients with hemodialysis].","authors":"Ana Yanzi Arroyo-Montes, Edward Ochoa-Tapia","doi":"10.5281/zenodo.13306713","DOIUrl":"https://doi.org/10.5281/zenodo.13306713","url":null,"abstract":"<p><strong>Background: </strong>Depression and anxiety affect with persistent sadness, low mood, fear and loss of interest in daily activities. Therefore, it is important to consider hemodialysis patients with psychological disorders in primary care.</p><p><strong>Objective: </strong>To analyze the presence of depression and anxiety with the Beck inventory in patients with hemodialysis in the Family Medicine Unit No. 1.</p><p><strong>Material and methods: </strong>A cross-sectional, analytical study was carried out with a type of convenience sampling. based on the inclusion criteria all patients on hemodialysis morning-afternoon shift and excluding all who do not wish to participate or intellectual disability, sample of 53 patients. Beck's anxiety and depression inventory instrument was applied, and the Pearson correlation coefficient was used to assess the degree of association.</p><p><strong>Results: </strong>The sex with the greatest presence was male (57%) and the age range is 40-46 years with 22.6%, the relationship of patients with end-stage renal disease (ESRD) presented mild anxiety/depression, while patients with moderate anxiety presented intermittent depression, the level of anxiety was positively correlated with depression and anxiety (p = 0.877).</p><p><strong>Conclusions: </strong>ESRD decreases functional capacity, generating psychological disorders such as depression and anxiety, which is why joint management with psychology or psychiatry must be carried out.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142684123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Sirenomelia: a case report]. [Sirenomelia: a case report]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306810
Christian Emmanuel Rodríguez-Partida, Iván Israel Gutiérrez-Gómez
{"title":"[Sirenomelia: a case report].","authors":"Christian Emmanuel Rodríguez-Partida, Iván Israel Gutiérrez-Gómez","doi":"10.5281/zenodo.13306810","DOIUrl":"10.5281/zenodo.13306810","url":null,"abstract":"<p><p>Sirenomelia is a rare congenital anomaly characterized by fusion of the lower extremities and multiple visceral abnormalities. It usually has a lethal prognosis due to the severity of the associated abnormalities. We present the case of a 26-year-old female patient, in her second pregnancy without associated comorbidities, who was admitted to the Emergency department due to a 26-week pregnancy and anhydramnios. She subsequently underwent an ultrasound in the Maternal Fetal Medicine service, who performed the Sirenomelia diagnosis. It was decided to terminate the pregnancy due to the poor prognosis.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Detection of inborn errors of metabolism: guidelines in Mexico and other countries]. [检测先天性代谢错误:墨西哥和其他国家的指导方针]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306777
Sarahi Guerrero-Barrios, Mariana Chiquillo-Domínguez, Jorge Ayón-Aguilar, Sergio Elihu Rodriguez-Alfaro, Socorro Méndez-Martínez, Máximo Alejandro García-Flores
{"title":"[Detection of inborn errors of metabolism: guidelines in Mexico and other countries].","authors":"Sarahi Guerrero-Barrios, Mariana Chiquillo-Domínguez, Jorge Ayón-Aguilar, Sergio Elihu Rodriguez-Alfaro, Socorro Méndez-Martínez, Máximo Alejandro García-Flores","doi":"10.5281/zenodo.13306777","DOIUrl":"https://doi.org/10.5281/zenodo.13306777","url":null,"abstract":"<p><p>Inborn errors of metabolism (IEM), also known as inherited metabolic disorders, are rare but associated with significant morbidity and mortality. The incidence is variable in all regions, worldwide it ranges from 1 in 569 to 2500 live births (LBI). The objective of this work was to carry out a narrative review to identify the guidelines that guide the detection of EIMs through official sources from various countries. A total of 13 documents were identified, including protocols, books, manuals, programs and 4 official websites for the detection of EIMs. In general, there is variability in the selection of EIMs that are detected, from 4 to 61 EIMs, primary congenital hypothyroidism and pheniceltonuria are the two EIMs that are included in most screening programs, spinal atrophy and severe combined immunodeficiency are detected less frequently, the incidence of each EIM is variable between countries and even between states of the same country, with congenital hypothyroidism being the most common. The guidelines for the selection of EIMs are determined by the internal policies of each country, the incidence and economic resources. There is no universal standard for the detection of EIMs, but they all pursue the same purpose: detection, diagnosis and timely treatment. In parallel, it allows us to estimate with greater precision the frequency of these disorders.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The Pierde Kilos, Gana Vida strategy, scope and prospects]. [Pierde Kilos,Gana Vida 战略、范围和前景]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306787
María Nayeli Acosta-Gutiérrez, Julia Del Carmen Rodríguez-García, David Manuel Miranda-Canteros, Célida Duque-Molina, Ernesto Krug-Llamas, Alma Belen Membrila-Torres, Beatriz Nohemi Aguirre-Mendoza, Itzel Valtierra-Martinez, Joel Bailon-Brito, Diego Salomón Balcón-Caro
{"title":"[The Pierde Kilos, Gana Vida strategy, scope and prospects].","authors":"María Nayeli Acosta-Gutiérrez, Julia Del Carmen Rodríguez-García, David Manuel Miranda-Canteros, Célida Duque-Molina, Ernesto Krug-Llamas, Alma Belen Membrila-Torres, Beatriz Nohemi Aguirre-Mendoza, Itzel Valtierra-Martinez, Joel Bailon-Brito, Diego Salomón Balcón-Caro","doi":"10.5281/zenodo.13306787","DOIUrl":"https://doi.org/10.5281/zenodo.13306787","url":null,"abstract":"<p><strong>Background: </strong>The Pierde Peso, Gana Vida (Lose Weight, Gain Life) strategy is granted to patients with overweight or obesity, it started in 2022 with the purpose of ordering, integrating and making efficient actions in the care of overweight and obesity, however, its effectiveness is unknown.</p><p><strong>Objective: </strong>To analyze the changes in the following parameters: body weight, waist circumference, glucose, cholesterol and triglycerides in patients who received the strategy in the 35 IMSS state offices during the two semesters of 2022.</p><p><strong>Material and methods: </strong>A retrospective cohort study was conducted including 76,760 patients incorporated into the strategy in the two semesters of 2022. Trend analysis was performed before and after each semester of intervention. Analytical statistics were used for related samples with Student's t-test. SPPSS v25 software was used for data analysis.</p><p><strong>Results: </strong>Patients who received this strategy in each semester presented significant decrease in the parameters: body weight, waist circumference, glucose, cholesterol and triglycerides.</p><p><strong>Conclusions: </strong>The Pierde Peso, Gana Vida strategy makes the actions in obesity care efficient and allows achieving good results in the beneficiaries.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Administrative work program of de Educational Research and Teacher Training Center in Puebla]. [普埃布拉市教育研究和教师培训中心行政工作计划]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306718
Blanca Estela Ruiz-Barrón, Sarahi Guerrero-Barrios, Luz Karina Ramírez-Dueñas, Socorro Méndez-Martínez, Jorge Ayón-Aguilar, Máximo Alejandro García-Flores
{"title":"[Administrative work program of de Educational Research and Teacher Training Center in Puebla].","authors":"Blanca Estela Ruiz-Barrón, Sarahi Guerrero-Barrios, Luz Karina Ramírez-Dueñas, Socorro Méndez-Martínez, Jorge Ayón-Aguilar, Máximo Alejandro García-Flores","doi":"10.5281/zenodo.13306718","DOIUrl":"https://doi.org/10.5281/zenodo.13306718","url":null,"abstract":"<p><strong>Background: </strong>The Administrative Work Program at the Center for Educational Research and Teacher Training (CIEFD) was based on the approach of the administrative area to publicize the aspects covered by the environment and the daily operation of the Unit, since all of this is an essential part In order for the CIEFD to function correctly, it must also be verified that the work within the organization is carried out correctly and that each element fulfills its functions.</p><p><strong>Objetive: </strong>Describe the different aspects of the administrative work program of the Center for Educational Research and Teacher Training in Puebla.</p><p><strong>Material and methods: </strong>Qualitative narrative study that describes each of the important administrative areas in the CIEFD: Financial Resources, Material Resources, Human Resources, Conservation and Maintenance, Civil Protection, Competitiveness Model and IT Coordination.</p><p><strong>Results: </strong>Each administrative area of the CIEFD converges into an administrative program that is governed by its own regulations and it is the administrator's task to converge all these areas by coordinating all aspects of the workforce, directing and managing, as well as allocating the necessary resources (materials economic and human) to ensure that work flows can be effective and that the Center's goals and objectives are met.</p><p><strong>Conclusion: </strong>The administrative areas of the CIEFD are essential for the training of human resources, teaching and managerial professionalization.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142684119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Electroencephalographic patterns and their association with functional prognosis in anti-NMDA autoimmune encephalitis]. [抗 NMDA 自身免疫性脑炎的脑电图模式及其与功能性预后的关系]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306743
Christian Alejandro Aguilar-Vázquez, Nallely Denisse Ruvalcaba-Sánchez, Julián Alberto Hernández-Domínguez, Sergio De Jesús Aguilar Castillo
{"title":"[Electroencephalographic patterns and their association with functional prognosis in anti-NMDA autoimmune encephalitis].","authors":"Christian Alejandro Aguilar-Vázquez, Nallely Denisse Ruvalcaba-Sánchez, Julián Alberto Hernández-Domínguez, Sergio De Jesús Aguilar Castillo","doi":"10.5281/zenodo.13306743","DOIUrl":"10.5281/zenodo.13306743","url":null,"abstract":"<p><strong>Background: </strong>Autoimmune encephalitis is a rare disease with low incidence and prevalence but carries high rates of disability and potential fatality.</p><p><strong>Objective: </strong>To determine whether the presence of abnormal electroencephalographic patterns in patients with anti-NMDAR autoimmune encephalitis affects functional prognosis at 3 months.</p><p><strong>Material and methods: </strong>A retrospective, observational, analytical, longitudinal-cross-sectional study was conducted with a retrospective cohort.</p><p><strong>Results: </strong>Out of a total of 44 patients with anti-NMDAR autoimmune encephalitis, concerning electroencephalographic findings, 19 patients had a normal EEG result (43.2%), 18 had cortical dysfunction (40.9%), 7 had epileptiform reports (15.9%), and only 1 had a Delta Brush report (2.3%). The functional outcome of patients at 3 months measured by the modified Rankin Scale (mRS) was as follows: 3 patients without disability (6.8%), 6 patients with mild disability (13.6%), 17 patients with mild to moderate disability (38.6%), 9 patients with moderate to severe disability (20.5%), 1 patient bedridden (2.3%), and 2 deceased (5.6%).</p><p><strong>Conclusion: </strong>In our study, no association was found between an abnormal electroencephalographic pattern and a worse functional prognosis at 3 months in patients with autoimmune encephalitis. Although the electroencephalogram analyzed is the initial one, it would be necessary to assess later whether the persistence of abnormalities in the electroencephalogram is related to a greater number of sequelae and disabilities.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142684104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Tuberculosis: Analysis of the history and development of multiple antibiotic resistance]. [结核病:多种抗生素耐药性的历史和发展分析]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306769
Yolanda Monserrath Jacobo-Delgado, Luis Adrián De Jesús-González, Bruno Rivas-Santiago
{"title":"[Tuberculosis: Analysis of the history and development of multiple antibiotic resistance].","authors":"Yolanda Monserrath Jacobo-Delgado, Luis Adrián De Jesús-González, Bruno Rivas-Santiago","doi":"10.5281/zenodo.13306769","DOIUrl":"https://doi.org/10.5281/zenodo.13306769","url":null,"abstract":"<p><p>Tuberculosis is an ancient disease that has accompanied humanity for the last three thousand years and is considered the oldest infectious disease that still exists. The Mycobacterium tuberculosis bacillus was spread worldwide due to human migrations, and there is archaeological evidence of spinal tuberculosis cases in Egyptian and Andean mummies, as well as texts that attributed the disease to social factors before suspecting its infectious nature. Throughout its history, humans have dealt with this pathology by developing unusual and ineffective therapies, leading to a significant increase in the disease's mortality. In the past century, the first antibiotics were introduced, bringing hope to eradicate this disease. However, evolutionary pressure has led to the emergence of multi-drug-resistant strains. Today, the development of computational techniques, such as artificial intelligence, has given us new hope for generating drugs and potential immunomodulatory therapies. However, it is essential to remember that those who do not know their history are doomed to repeat it. In this review, we summarize the history of tuberculosis, analyzing theories of its possible origin, its discovery, the creation of the first empirical treatments, vaccines, the emergence of new antibiotics, and how the mycobacterium quickly develops resistance.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"137"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Radiological clinical profile of multiple cranial neuropathy and recurrence risk factors]. [多发性颅神经病的放射学临床概况及复发风险因素]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-09-05 DOI: 10.5281/zenodo.10814313
Alejandra Martínez-Vázquez, Ricardo Jorge García-Bermúdez, Julián Alberto Hernández-Domínguez, José Alfredo Sierra-Ramírez
{"title":"[Radiological clinical profile of multiple cranial neuropathy and recurrence risk factors].","authors":"Alejandra Martínez-Vázquez, Ricardo Jorge García-Bermúdez, Julián Alberto Hernández-Domínguez, José Alfredo Sierra-Ramírez","doi":"10.5281/zenodo.10814313","DOIUrl":"10.5281/zenodo.10814313","url":null,"abstract":"<p><strong>Background: </strong>Multiple cranial neuropathies (MCN) are the dysfunction of 2 or more cranial nerves, simultaneously or sequentially. The most common causes are tumors, followed by vascular and traumatic causes, central nervous system infections and Guillain-Barré syndrome and its variants.</p><p><strong>Objective: </strong>To identify the radiological clinical profile of MCN in patients of a tertiary-care hospital.</p><p><strong>Material and methods: </strong>Observational, cross-sectional, retrospective and analytical study in patients of 18 years of age or older, with a diagnosis of MCN. It was used descriptive statistics, and normality curves were determined. To establish differences, it was used chi-squared or Student's t test with the statistical package SPSS, version 29.</p><p><strong>Results: </strong>46 patients with a mean age 49 years (± 16) were studied. 29 (63%) were male. Findings in the magnetic resonance of the skull were normal in 34%; the reinforcement of the cavernous sinus in 26%. Non-infectious inflammatory was the most frequent etiology (43%). 83% of the inflammatory etiology presented improvement at discharge while those of non-inflammatory etiology were discharged without improvement (odds ratio [OR] 8, p 0.001). 87% had pain in their clinical picture unlike subjects with non-inflammatory etiology (OR 4, p < 0.01). 73% of the population with inflammatory etiology presented recurrence, and none of the subjects with a non- inflammatory cause (OR 0.5, p 0.022).</p><p><strong>Conclusions: </strong>The most common presentation of MCN in our study was cavernous sinus syndrome or sphenoidal cleft, with a non-acute course. The possibility of documenting an inflammatory etiology impacts the risk of recurrence and improvement upon hospital discharge.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 suppl 2","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142735479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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