Revista medica del Instituto Mexicano del Seguro Social最新文献_第9页

[Plasmid-mediated colistin resistance in pathogenic bacteria]. 病原菌质粒介导的粘菌素耐药性。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-05-06 DOI: 10.5281/zenodo.18715405

Néstor Casillas-Vega, Soraya Mendoza-Olazarán

{"title":"[Plasmid-mediated colistin resistance in pathogenic bacteria].","authors":"Néstor Casillas-Vega, Soraya Mendoza-Olazarán","doi":"10.5281/zenodo.18715405","DOIUrl":"10.5281/zenodo.18715405","url":null,"abstract":"Plasmid-mediated mcr colistin resistance has emerged as a growing global health threat by undermining one of the last therapeutic options against multidrug-resistant Gram-negative bacilli. This study provides a systematic and critical review of literature published between 2015 and 2025, including PubMed, Scopus, GenBank, and World Health Organization (WHO) reports. We analyzed the global distribution, prevalence, genetic variants, molecular mechanisms, diagnostic tools, and clinical implications of mcr. Findings reveal widespread dissemination across humans, animals, and the environment, with the highest burden in Asia and an alarming increase in Latin America. Variants such as mcr-3 and mcr-9 are particularly concerning due to their coexistence with carbapenemase genes, raising the risk of pan-resistant strains. Clinically, these infections are associated with high mortality, prolonged hospital stays, and increased costs, while asymptomatic intestinal carriage facilitates silent spread. Strengthening microbiological and genomic surveillance, implementing rapid diagnostic methods, regulating polymyxin use, and fostering novel therapeutic alternatives are urgently needed. Plasmid-mediated colistin resistance should not be seen as an isolated phenomenon but as a complex clinical, epidemiological, and social challenge requiring immediate and coordinated action to prevent a post-antibiotic era.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 3","pages":"e6845"},"PeriodicalIF":0.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13186539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147848261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Implementation sciences: Conceptual frameworks and an illustrative example of PRONAM]. [实施科学：概念框架和PRONAM的一个说明性例子]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-05-06 DOI: 10.5281/zenodo.18715217

Tom McCutchan, Marlene López-Sánchez, Rodolfo Rivas-Ruiz

引用次数: 0

[Effect of Vimala infant massage on mothers with postpartum depression]. 【维玛拉婴儿按摩对产后抑郁症母亲的影响】。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-05-06 DOI: 10.5281/zenodo.18715361

Alma Patricia González, Miriam Alejandra Reyes-Méndez, Carlos Paque-Bautista, Fernanda Jazmín Rodríguez-Ramírez, Gloria Patricia Sosa-Bustamante

{"title":"[Effect of Vimala infant massage on mothers with postpartum depression].","authors":"Alma Patricia González, Miriam Alejandra Reyes-Méndez, Carlos Paque-Bautista, Fernanda Jazmín Rodríguez-Ramírez, Gloria Patricia Sosa-Bustamante","doi":"10.5281/zenodo.18715361","DOIUrl":"10.5281/zenodo.18715361","url":null,"abstract":"Background: Postpartum depression (PPD) significantly affects maternal and infant health. Infant massage (IM) can help reduce depressive symptoms, feelings of guilt, strengthen maternal confidence, and improve the mother-child bond.Objective: To evaluate the effects of a Vimala IM intervention in newborns (NB) on their mothers with PPD.Material and methods: Quasi-experimental study. Mothers aged 18 to 45 years with term and late preterm newborns were included. The Edinburgh Postnatal Depression Scale (EPDS) was applied within the first 8 hours postpartum, and mothers were divided into 2 groups based on their score: with and without PPD. Both groups received training on Vimala IM, and 72 hours postpartum the EPDS was administered again.Results: A total of 90 mothers were analyzed. Before discharge, 23.33% exhibited symptoms of PPD, higher than the global reported rate (17.22%). After the Vimala massage intervention, the proportion of mothers with depressive symptoms decreased to 11.11% (p = 0.02). The item related to self-blame showed a delta of -34 in affirmative responses post-intervention. The absence of a partner showed risk for PPD, odds ratio (OR) 4.00 (1.03-15.51) p = 0.03.Conclusions: Vimala IM is an effective intervention in reducing PPD symptoms, particularly self-blame. The absence of a partner increased the risk of developing PPD by up to 4 times.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 3","pages":"e6852"},"PeriodicalIF":0.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13183353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147848210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Psychoeducation among women with breast cancer and emotional symptoms]. [对患有乳腺癌和情绪症状的妇女进行心理教育]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-05-06 DOI: 10.5281/zenodo.18715270

Livier Ortiz-Coronado, José Eduardo Huerta-Lépez, Martha Alicia Hernández-González, Rebeca Monroy-Torres, José María De La Roca-Chiapas, Benigno Linares-Segovia, Juan Germán Celis-Quintal

{"title":"[Psychoeducation among women with breast cancer and emotional symptoms].","authors":"Livier Ortiz-Coronado, José Eduardo Huerta-Lépez, Martha Alicia Hernández-González, Rebeca Monroy-Torres, José María De La Roca-Chiapas, Benigno Linares-Segovia, Juan Germán Celis-Quintal","doi":"10.5281/zenodo.18715270","DOIUrl":"10.5281/zenodo.18715270","url":null,"abstract":"Background: Breast cancer (BC) is the most frequent neoplasm. As a consequence of the oncologic treatment, there are diverse adverse effects, as the emotional ones. Treatment options for emotional symptoms like anxiety, depression or stress are limited.Objective: To analyze the effectiveness of psychoeducational workshops among women with BC over the anxiety and depression symptoms.Material and methods: A randomized clinical trial by blocks with 42 BC patients in stages II and III of the disease, distributed into 2 groups of 21 cases (intervention) and 21 controls. There were 9 psychoeducational workshops performed weekly. It was carried out an initial and final measurement according to the Hospital Anxiety and Depression Scale (HADS).Results: For the intervention group, the median score for anxiety was 9.09 at the beginning of the study and 5.85 at the end (p = 0.0005). In the control group, the median for anxiety was 8.7 and 6.7 at the end (p = 0.0494). According to the depression symptoms, the median for the intervention group was 5 at the beginning and 3.2 at the end (p = 0.0216). For the control group, the median was 4.7 at the beginning and 4.6 at the end (p = 0.6359).Conclusion: The psychoeducational workshops demonstrated effectiveness to decrease the symptom burden for anxiety and depression. Early education and counselling for recently diagnosed BC patients should be considered part of the treatment to prevent and decrease these symptoms.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 3","pages":"e6694"},"PeriodicalIF":0.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13175585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147848264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Artificial intelligence algorithm for bone age estimation]. [骨龄估计的人工智能算法]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-05-06 DOI: 10.5281/zenodo.18715240

Catalina Peralta-Cortázar, Zulem Santiago-Loya, Talia Minerva Rivera-Villanueva, Daniel Omar Pérez-Godínez, Oscar Abraham José Padilla-Solís, Agustín Ramiro Urzúa-González, Alma Patricia González, Carlos Paque-Bautista, José Luis Felipe Luna-Anguiano, Gloria Patricia Sosa-Bustamante

{"title":"[Artificial intelligence algorithm for bone age estimation].","authors":"Catalina Peralta-Cortázar, Zulem Santiago-Loya, Talia Minerva Rivera-Villanueva, Daniel Omar Pérez-Godínez, Oscar Abraham José Padilla-Solís, Agustín Ramiro Urzúa-González, Alma Patricia González, Carlos Paque-Bautista, José Luis Felipe Luna-Anguiano, Gloria Patricia Sosa-Bustamante","doi":"10.5281/zenodo.18715240","DOIUrl":"10.5281/zenodo.18715240","url":null,"abstract":"Background: Bone age (BA) estimation with automated methods can eliminate interindividual variation.Objective: To evaluate BA by creating an artificial intelligence (AI) algorithm in a pediatric population from the Bajío region of Mexico.Material and methods: Observational, cross-sectional, retrospective, analytical study. Left-hand radiographs of children under 18 years of age, obtained from the Radiology Department database were included to create the AI algorithm for estimating BA. The BA result obtained by AI was compared with that obtained by 2 expert observers using the Greulich and Pyle method.Results: 271 radiographs were analyzed to assess BA and this was similar between observers 1, 2, and AI when considering all images (p = 0.68). The time taken to estimate BA was longer with AI (p < 0.001). AI measurement showed no differences between chronological age (CA) and BA when considering both the total number of images (p = 0.12) and when they were distributed by age group: < 6 years, 6 to < 10 years, and ≥ 10 years (p = 0.60, p = 0.06, p = 0.67, respectively). The highest EO concordance correlation coefficients (CCCs) were recorded when all images were evaluated (observer 1 and 2, observer 1 and AI, and observer 2 and AI [p < 0.001, in all 3 scenarios]).Conclusions: The AI algorithm allows for objective estimation of BA in children and adolescents as a first training approach; its refinement will optimize its use and utility in clinical practice.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 3","pages":"e6753"},"PeriodicalIF":0.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13175586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147848193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Glycemic control of type 2 diabetes: primary care pre-pandemic versus COVID-19 pandemic]. [2型糖尿病的血糖控制：大流行前的初级保健与COVID-19大流行]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-05-06 DOI: 10.5281/zenodo.18715293

Guadalupe Soto-Estrada, Yolanda Mares-Gutiérrez, Manuel García-Minjares, Adrián Martínez-González, Adrián Israel Martínez-Franco

{"title":"[Glycemic control of type 2 diabetes: primary care pre-pandemic versus COVID-19 pandemic].","authors":"Guadalupe Soto-Estrada, Yolanda Mares-Gutiérrez, Manuel García-Minjares, Adrián Martínez-González, Adrián Israel Martínez-Franco","doi":"10.5281/zenodo.18715293","DOIUrl":"10.5281/zenodo.18715293","url":null,"abstract":"Background: Keeping an adequate glycemic control is a major global challenge. Approximately 42% of individuals achieve the recommended HbA1c targets.Objective: To compare glycemic control in 2 independent cohorts of patients with type 2 diabetes mellitus treated before and during the COVID-19 pandemic in primary care in Mexico City.Material and methods: Analytical observational study; records of 3598 patients with 2 HbA1c determinations (2562 pre-pandemic and 1036 pandemic) from 213 health units were analyzed. Means, proportions, and t and chi-squared tests were calculated; metabolic control was defined as HbA1c ≤ 8%.Results: Mean HbA1c was 9.1% in both groups in the first measurement; at the last measurement, it was lower in the pre-pandemic group (8.0% vs. 8.3%; p < 0.001). The percentage of controlled patients increased from 38.5% to 58.5% pre-pandemic and from 37.8% to 54.2% during the pandemic (p = 0.017). Dual oral therapy achieved the greatest increase in control (22.5% pre-pandemic, 28.3% pandemic); isolated insulin therapy and absence of pharmacological treatment were less effective under pandemic conditions.Conclusions: The pandemic was associated with lower glycemic control; however, regimens with 1 or 2 oral antidiabetic agents retained their effectiveness. Ensuring continuity of care, drug supply, and support for lifestyle measures will be crucial in future crises.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 3","pages":"e6835"},"PeriodicalIF":0.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13175584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147848176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Efficacy of octreotide LAR and lanreotide autogel in acromegaly assessed by SAGIT]. [SAGIT评估奥曲肽LAR和lanreotide autol治疗肢端肥大症的疗效]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-05-06 DOI: 10.5281/zenodo.18715331

Francisco Javier Núñez-Martínez, Alejandro de Jesús Chávez-Lárraga, Enrique Hernández-Salazar, Brian Humberto Martínez-Sánchez, Jorge Isaac Velasco-Santos

{"title":"[Efficacy of octreotide LAR and lanreotide autogel in acromegaly assessed by SAGIT].","authors":"Francisco Javier Núñez-Martínez, Alejandro de Jesús Chávez-Lárraga, Enrique Hernández-Salazar, Brian Humberto Martínez-Sánchez, Jorge Isaac Velasco-Santos","doi":"10.5281/zenodo.18715331","DOIUrl":"10.5281/zenodo.18715331","url":null,"abstract":"Background: Biochemical control has been the main objective in the treatment of acromegaly; however, GH and IGF-1 levels do not necessarily translate into clinical response, as they fail to account for the complexity of symptoms and patients' perceptions. The SAGIT instrument was developed to assist in assessing the status and evolution of the disease in patients with acromegaly and facilitate decision-making.Objective: To compare the efficacy of octreotide LAR and lanreotide autogel in managing patients with acromegaly using the SAGIT instrument.Material and methods: Observational, unicentric study, conducted in 2022 at a referral hospital in León, Guanajuato, Mexico.Results: Of 37 patients evaluated, 26 were included. 13 (50%) received lanreotide autogel and 11 (42.3%) received octreotide LAR. Disease control, as measured by IGF-1 levels, was achieved in 10 patients (42.3%). When assessing control using the SAGIT instrument, 8 patients (30.7%) met control criteria. Octreotide LAR showed greater disease control as assessed by SAGIT compared to lanreotide autogel (p = 0.043).Conclusions: Based on the SAGIT instrument, octreotide LAR is more effective for disease control in patients with acromegaly than in those patients treated with lanreotide. The preferential use of octreotide LAR could be recommended in resource-limited settings.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 3","pages":"e6706"},"PeriodicalIF":0.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147848208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Sinonasal ameloblastoma: Clinical case presentation and literature review]. [鼻窦成釉细胞瘤：临床表现及文献复习]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-05-06 DOI: 10.5281/zenodo.18715493

Francisco Javier Martínez-Fernández, Fany Gabriela Juárez-Aguilar

{"title":"[Sinonasal ameloblastoma: Clinical case presentation and literature review].","authors":"Francisco Javier Martínez-Fernández, Fany Gabriela Juárez-Aguilar","doi":"10.5281/zenodo.18715493","DOIUrl":"10.5281/zenodo.18715493","url":null,"abstract":"Background: Sinonasal ameloblastoma is considered a locally benign, rare, and locally aggressive neoplasm. It is included within the so-called peripheral ameloblastomas. The symptoms are nonspecific, such as epistaxis, rhinorrhea, and nasal obstruction. The diagnosis requires a broad approach, imaging studies and complete clinical history; however, the histopathological diagnosis is the gold standard. As for treatment, the mainstay is surgical; however, it is currently being studied to complement it with radiotherapy or BRAF inhibitors. The objective was to present a clinical case of a Mexican patient, as well as to make a bibliographic review of the subject.Clinical case: Woman originally from and resident of Mexico City who began with hearing loss, rhinorrhea, and nasal obstruction. Imaging studies revealed a mass that completely occupied the right maxillary sinus and the ipsilateral nasal cavity. The pathology study revealed that it was an ameloblastoma.Conclusions: Although rare, the described case presented the clinical characteristics described in the international literature, and even though there are no standardized guidelines for the treatment of this entity, appropriate treatment was provided in accordance with international recommendations for these cases.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 3","pages":"e6881"},"PeriodicalIF":0.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13196994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147848279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Economic evaluation in the health sector: The link between economic and health variables]. [卫生部门的经济评价：经济变量与卫生变量之间的联系]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-05-06 DOI: 10.5281/zenodo.18715429

Gustavo Inzunza-Cervantes, Alibe Natanai Peña-Valenzuela, Carmen Lucía García-Álvarez

引用次数: 0

[Psychiatry as clinical neuroscience]. [精神病学作为临床神经科学]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2026-05-06 DOI: 10.5281/zenodo.18715437

José Luis Jiménez-López

{"title":"[Psychiatry as clinical neuroscience].","authors":"José Luis Jiménez-López","doi":"10.5281/zenodo.18715437","DOIUrl":"10.5281/zenodo.18715437","url":null,"abstract":"For more than a century, psychiatry has established its clinical practice on syndrome-based descriptions grouped into exclusive diagnostic categories and on the prescription of psychotropic drugs aimed at modifying signs and symptoms, with etiological hypotheses formulated from different theoretical frameworks, ranging from psychoanalytic to neurobiological. Recent research from a neuroscientific theoretical framework suggests that different psychiatric illnesses are interconnected at different levels. The approach to mental disorders from this new perspective has generated more precise etiological hypotheses, has favored the development of initiatives that recommend a radical change in psychiatric taxonomy, and has oriented pharmacological research to other therapeutic targets. This article raises the possibility of psychiatry being positioned as a clinical neuroscience based on studies on brain connectivity as a substrate of mental functioning (Human Connectome Project), transdiagnostic nosological classification initiatives from a dimensional and spectral perspective (Research Domain Criteria and Hierarchical Taxonomy of Psychopathology) the new psychopharmacological nomenclature based on neurosciences and the findings in genomic association studies. The paradigm shift for the approach to mental disorders also includes the training of specialists in psychiatry, which is why the inclusion of neuroscience subjects in medical residency programs is recommended.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 3","pages":"e6687"},"PeriodicalIF":0.0,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13193626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147848335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0