Revista medica del Instituto Mexicano del Seguro Social最新文献_第8页

[POEMS syndrome. Report of three cases and literature review]. [POEMS 综合征：三个病例的报告和文献综述]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-07-01 DOI: 10.5281/zenodo.11397295

Crhistian Alejandro Aguilar-Vázquez, Nallely Denisse Ruvalcaba-Sánchez

{"title":"[POEMS syndrome. Report of three cases and literature review].","authors":"Crhistian Alejandro Aguilar-Vázquez, Nallely Denisse Ruvalcaba-Sánchez","doi":"10.5281/zenodo.11397295","DOIUrl":"10.5281/zenodo.11397295","url":null,"abstract":"Background: POEMS syndrome is a debilitating paraneoplastic disorder associated with plasma cell neoplasia. Clinically, it is characterized by predominantly demyelinating peripheral neuropathy that often starts in the pelvic limbs, organomegaly, endocrinopathy, skin changes, and elevated serum M protein. Diagnosis requires meeting a set of clinical criteria in which polyradiculoneuropathy and plasma cell disorder are the two mandatory criteria. The aim of this article is to describe 3 clinical cases, their diagnostic approach, and therapeutic management.Clinical cases: In this study, three clinical cases with features compatible with POEMS syndrome are presented. Nerve conduction studies revealed demyelinating involvement with sensory-motor impairment, and evidence of a monoclonal spike was found. Treatment was successful in two cases and partially effective in one, although the latter was associated with delayed diagnosis.Conclusion: Despite significant advancements in understanding the pathophysiology and treatment of this disease, diagnosis remains challenging, especially in locations lacking the necessary resources for accurate diagnosis. It is essential to emphasize that it requires a multidisciplinary approach. The prognosis of this disease is closely linked to early diagnosis. Here, we describe three cases from a reference center in Mexico to increase awareness of the disease's diagnosis.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 4","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142640498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Health Regulation in High Specialty Medical Units of the IMSS]. [社会保障局高级专科医疗单位的卫生条例]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-07-01 DOI: 10.5281/zenodo.11397191

Carlos Fredy Cuevas-García, Martha Patricia Galán-Hermosillo, Víctor Daniel Martínez-Enciso, Saúl Armando Herrera-Belmares, Miguel Angel Magdaleno-Lucio

{"title":"[Health Regulation in High Specialty Medical Units of the IMSS].","authors":"Carlos Fredy Cuevas-García, Martha Patricia Galán-Hermosillo, Víctor Daniel Martínez-Enciso, Saúl Armando Herrera-Belmares, Miguel Angel Magdaleno-Lucio","doi":"10.5281/zenodo.11397191","DOIUrl":"10.5281/zenodo.11397191","url":null,"abstract":"In accordance with the Sustainable Development Goals (SDG) of the 2030 Agenda of the United Nations General Assembly, the National Development Plan (PND) 2019-2024 includes in its Guiding Principles, \"Leave no one behind; leave no one out\", and for its part, the Mexican Social Security Institute (IMSS) implements strategies to guarantee access to universal health through the granting of economic, social and medical benefits, whose objective is to promote, maintain and recover . health care, however, to be carried out with effectiveness, quality and safety, these activities require Health Care Institutions authorization. In this work, the Operational Plan for Health Security in Medical Units of the IMSS (POSSUM IMSS) is disclosed, all the Licenses in all Third Level Care hospitals, whose objective was to comply with the instructions of the General Directorate (DG). on February 2, 2023, within the framework of the Safe Hospital program, to process 100% of Licenses in High Specialty Medical Units (UMAE). After its implementation, on November 10, 2023, the entire UMAE reached 100% Global Compliance in Licenses. The POSSUM IMSS contributes to regulatory certainty to achieve the transformation towards a more modern, inclusive, safe and efficient IMSS for the user and worker population and is susceptible to being implemented in other public and private sector institutions.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 4","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Seroprevalence and risk factor for hepatitis C in Nogales, Sonora]. [索诺拉州诺加莱斯的丙型肝炎血清流行率和风险因素]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-07-01 DOI: 10.5281/zenodo.11397093

Jesús Antonio Pérez-Mercado, Diana Lizeth Gallegos-Durazo, Jorge Rafael Hernández-Donnadieu, Edgar Daniel Copado-Villagrana

{"title":"[Seroprevalence and risk factor for hepatitis C in Nogales, Sonora].","authors":"Jesús Antonio Pérez-Mercado, Diana Lizeth Gallegos-Durazo, Jorge Rafael Hernández-Donnadieu, Edgar Daniel Copado-Villagrana","doi":"10.5281/zenodo.11397093","DOIUrl":"https://doi.org/10.5281/zenodo.11397093","url":null,"abstract":"Background: Hepatitis C Virus (HCV) infection represents a global public health problem, but in Mexico, the Ministry of Health through the National Epidemiological Surveillance System (SINAVE) only reports the distribution of incident cases by state, sex and epidemiological week.Objective: To determine the seroprevalence and factors associated with HCV in beneficiaries of a Family Medicine Unit of the Mexican Social Security Institute (IMSS) in the city of Nogales, Sonora, located on the border between Mexico and the United States.Material and methods: Cross-sectional study that included 145 beneficiaries with rapid HCV antibody test results. Information on risk factors was obtained through direct questioning. To compare groups of reactive and non-reactive patients, Fisher's Exact Test was used and a Logistic Regression model to determine Odds Ratio (OR) values. A P value <0.05 was considered statistically significant.Results: A seroprevalence of 2.8% (95%CI: 0.8 - 6.9) was determined and through the logistic regression model it was found that the history of transfusions (OR: 151.2, 95%CI: 5.9 - 3.858.0) and the use of intranasal drugs (OR: 20.81, 95%CI: 1.3 - 331.3) increase the risk of infection.Conclusions: The seroprevalence of HCV in Nogales is higher than that of the rest of Mexico. Recent studies establish a history of transfusion as a risk factor, but few have explored intranasal drug use.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 4","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Diffuse gastric carcinoma in the youth: Case report]. [青年弥漫性胃癌：病例报告]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-07-01 DOI: 10.5281/zenodo.11397326

Rodrigo González-Aguirre, Héctor Ronaldo Sánchez-Moreno, Eulalio Alberto Gutiérrez-Rodríguez, Julio Alexis Arce-Hernández, Francisco Alfonso Solis-Galindo

{"title":"[Diffuse gastric carcinoma in the youth: Case report].","authors":"Rodrigo González-Aguirre, Héctor Ronaldo Sánchez-Moreno, Eulalio Alberto Gutiérrez-Rodríguez, Julio Alexis Arce-Hernández, Francisco Alfonso Solis-Galindo","doi":"10.5281/zenodo.11397326","DOIUrl":"10.5281/zenodo.11397326","url":null,"abstract":"Background: Gastric cancer is the 5th most common neoplasm in Mexico with an incidence of 13.6 per 100,000 inhabitants. In those under 35 years of age, it represents the 13th cause of cancer with an incidence of 0.37 per 100,000 inhabitants.Clinical case: We present the case of a 21-year-old male patient treated at the High Specialty Medical Unit No. 71 of the Instituto Mexicano del Seguro Social in Torreón, Coahuila, Mexico. He started with burning epigastric pain lasting two months, which progressed with nausea, vomiting, hyporexia and weight loss of 10 kg in two months. Helicobacter pylori (+) in antigen in feces. Jaundice was added with a negative viral panel, laboratory tests with a cholestatic pattern. It was not possible to perform endoscopic cholangiopancreatography (ERCP) due to poor stomach compliance, with the presence of an atypical giant ulcer; the biopsy reported a neoplasm suggestive of diffuse adenocarcinoma. He was admitted for evaluation by interventional radiology for bile duct diversion. Immunohistochemistry (IMQ) reported diffuse gastric adenocarcinoma CD 45 (-), CK AE1 / AE3: (+) intense in neoplastic cells, HER 2 NEU (+). Treatment consisted of bile duct diversion, nasojejunal tube nutrition, and palliative treatment. The patient died one month after hospital admission.Conclusion: The objective is to generate knowledge of the intentional search for the pathology to make timely diagnoses, in addition to reporting the atypical HER 2 NEU (+) presentation.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 4","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142640474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Leuko-glycemic index as a marker of inflammation and endothelial dysfunction in overweight and obesity]. [白细胞血糖生成指数作为超重和肥胖症患者炎症和内皮功能障碍的标志物]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-07-01 DOI: 10.5281/zenodo.11397066

Diana Carolina Villalpando-Sánchez, Anel Gómez-García

{"title":"[Leuko-glycemic index as a marker of inflammation and endothelial dysfunction in overweight and obesity].","authors":"Diana Carolina Villalpando-Sánchez, Anel Gómez-García","doi":"10.5281/zenodo.11397066","DOIUrl":"https://doi.org/10.5281/zenodo.11397066","url":null,"abstract":"Background: Overweight (OW) and obesity (OB) are major health problems both in Mexico and the world. Because of the chronic low-grade inflammatory state that characterizes OW and OB, they are considered as cardiovascular risk factors. The leuko-glycemic index (LGI) is a ratio used as a prognostic factor to predict complications in patients with vascular diseases.Objective: To assess the utility of LGI index as an inflammatory and endothelial dysfunction marker in patients with OW and OB.Material and methods: Comparative cross-sectional study in 124 patients of Family Medicine Unit 80 of Mexican Social Security Institute. Young adults aged between 18 - 50 years old, and BMI between 18.5 and 40 kg/m2, without diagnosis of chronic diseases, auto immunities or immunodeficiencies were included. Bioelectrical impedance (weight, height, BMI, % body fat, lean mass) and blood sample (blood count, glucose, lipid profile, inflammatory, endothelial dysfunction markers) were assessed. Patients were grouped according to their BMI: OB, OW and normal weight (NW).Results: LGI was found to be significantly elevated in OB and OW patients vs. NW. LGI correlated positively with inflammation and DE markers: IL-6, TNF-α, vWF. A value ≥ 405 was estimated with ROC curves as cut-off point for LGI to predict the likelihood of inflammation and ED in OW and OB patients.Conclusions: ILG is relevant as a predictive marker of cardiovascular disease by reflecting inflammation and endothelial dysfunction in patients with OW and OB.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 4","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Aortic dissection: A challenge for the emergency medicine? A case report]. [主动脉夹层：急诊医学的挑战？病例报告]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-07-01 DOI: 10.5281/zenodo.11397340

José Juan Dávila-Castro, Diana Nagtheli Lemus-Galván

{"title":"[Aortic dissection: A challenge for the emergency medicine? A case report].","authors":"José Juan Dávila-Castro, Diana Nagtheli Lemus-Galván","doi":"10.5281/zenodo.11397340","DOIUrl":"10.5281/zenodo.11397340","url":null,"abstract":"Background: Acute aortic syndrome was fully described in 2001, it refers to a heterogeneous group of patients with a set of signs and symptoms where the main one is aortic pain. This syndrome encompasses a group of four acute aortic conditions: aortic dissection (AD), intramural hematoma, penetrating aortic ulcer, and incomplete dissection. Aortic dissection usually follows the sudden onset of acute chest pain, which is worse at the point of manifestation.Case report: 50-year-old male patient admitted to the emergency department for abdominal pain; he reported a history of systemic arterial hypertension for 22 years of diagnosis, treatment with Irbesartan (225 mg/day), chronic kidney disease without replacement therapy, with previous appendectomy 30 years ago.Conclusion: The diagnostic difficulty of acute aortic syndrome in the emergency department has been a challenge due to the diffuse clinical picture in which it presents, but it is extremely important to have a high level of suspicion, to keep in mind that AD is an underdiagnosed etiology and to relate it to risk factors. The importance of establishing a timely diagnosis is a priority, since mortality increases from 1 to 2% per hour of elapsed time.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 4","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142640471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Electromyography in atypical variants of motor neuron disease: a case series]. [运动神经元病非典型变异型的肌电图：病例系列]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-07-01 DOI: 10.5281/zenodo.11397347

Allan Natanael Salmerón-Mendoza, Crhistian Alejandro Aguilar-Vázquez, Sergio de Jesús Aguilar-Castillo

{"title":"[Electromyography in atypical variants of motor neuron disease: a case series].","authors":"Allan Natanael Salmerón-Mendoza, Crhistian Alejandro Aguilar-Vázquez, Sergio de Jesús Aguilar-Castillo","doi":"10.5281/zenodo.11397347","DOIUrl":"10.5281/zenodo.11397347","url":null,"abstract":"Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects both the upper and lower motor neurons, it has a heterogeneous clinical presentation, there are atypical variants that differ from the classic form of the disease. The criteria for diagnosis have evolved over time, with the support of electromyography (EMG), we present a patient series with these variants in which EMG was crucial to make the diagnosis.Clinical cases: Six cases are described with atypical presentation of motor neuron disease, for the isolated bulbar ALS phenotype, three cases are reported: two male patients (68 and 62 years old) and one woman (33 years old), with initial symptoms in the bulbar segment and late progression. to a second segment, corroborating characteristic findings by EMG. For the variant of Vulpian-Bernhardt syndrome (VBS), two male patients aged 82 and 72 years are reported, with initial symptoms in the thoracic segment with electromyographic support for the diagnosis; Finally, a case of amyotrophic diplegia of the legs (APD) is described in a 50-year-old female patient with symptoms isolated to the pelvic limbs, with a slow clinical evolution, corroborated by EMG with involvement of other spinal segments.Conclusions: ALS a spectrum of motor neuron disease, a neurodegenerative disease of the CNS, without curative treatment and one with a fatal outcome, the diagnosis of ELA is complex and becomes more complex for atypical phenotypes, as observed in the presented cases EMG is an essential part of the approach and part of the diagnostic criteria.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 4","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142640476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Risk of postpartum depression in primary care]. [初级保健中的产后抑郁风险]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-07-01 DOI: 10.5281/zenodo.11397005

Brenda Fabiola Barrera-Mondragón, Víctor Manuel Camarillo-Nava, Blanca Berenice García-Rivera

{"title":"[Risk of postpartum depression in primary care].","authors":"Brenda Fabiola Barrera-Mondragón, Víctor Manuel Camarillo-Nava, Blanca Berenice García-Rivera","doi":"10.5281/zenodo.11397005","DOIUrl":"10.5281/zenodo.11397005","url":null,"abstract":"Background: Postpartum depression (PPD) is a severe mental disorder that can affect up to 56% of Latina women. PPD has multiple origins and affects maternal well-being, health and behavior, as well as child development.Objective: to analyze the risk of postpartum depression in a primary care center.Material and methods: observational, cross-sectional, retrospective study in patients entitled to primary care, who were in the postpartum period. Likert-type surveys were carried out, based on the Edinburgh Scale, collecting sociodemographic factors, in order to establish the associated risk factors. The association between the study outcome (risk of postpartum depression) with each independent variable was determined using Odds ratio and multivariate models.Results: 79 postpartum patients were included, the average age was 29 years (± 5), 46.8% with a high risk of depression, and 53.2% without risk of postpartum depression. The main factor associated with being able to present a high risk of postpartum depression was low socioeconomic level in 94.6%, other variables did not have statistical significance.Conclusions: the frequency of being at high risk for postpartum depression in our study was similar to that reported by the Pan American Health Organization 2018, with a frequency of 56% in Mexican and Latin American women. The main risk factor was economic aspects rather than social aspects.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 4","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Hyperthermia on colorectal cancer: gold nanoshells-mediated photothermal therapy]. [大肠癌热疗：金纳米壳介导的光热疗法]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-07-01 DOI: 10.5281/zenodo.11397181

Sarah Eliuth Ochoa-Hugo, Yanet Karina Gutiérrez-Mercado, Alejandro Arturo Canales-Aguirre, Rodolfo Hernández-Gutiérrez

{"title":"[Hyperthermia on colorectal cancer: gold nanoshells-mediated photothermal therapy].","authors":"Sarah Eliuth Ochoa-Hugo, Yanet Karina Gutiérrez-Mercado, Alejandro Arturo Canales-Aguirre, Rodolfo Hernández-Gutiérrez","doi":"10.5281/zenodo.11397181","DOIUrl":"10.5281/zenodo.11397181","url":null,"abstract":"Colon cancer or colorectal cancer is one of the most common malignant neoplasms in the world, characterized by uncontrolled cell growth on the colon mucosa. Treatment approaches depend primarily on the characteristics of the tumor´s localization, size, metastasis, and the health status of the patient. Nanomedicine shows itself as a novelty strategy to overcome the limitations of the therapies used in the clinic due to the disregard of the mechanisms associated with multidrug resistance because of the nanometric size of the particles utilized. Gold nanoshells are spheric structures of an approximate size of 30 nm, coated with an ultrathin gold layer that can absorb near-infrared light and convert it to thermal energy to produce hyperthermia on in vivo models of cancer tumors. Nanoparticles-assisted hyperthermia consists of control, direct, and specific heating against the tumor cells by nanoparticle irradiation with an external power source capable of increasing temperature to 39°C - 45°C without damaging surrounding healthy tissue. Compared with other nanomaterials, gold nanoshells show high biocompatibility and low cytotoxicity, which is why adjuvant chemotherapy and hyperthermia on gold nanoshells is a novel and promising approach for the treatment of colorectal cancer.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 4","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Coronary artery disease multivessel not amenable to revascularization: contemporary cohort]. [不适于血管再通的多血管冠状动脉疾病：当代队列]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-07-01 DOI: 10.5281/zenodo.11397136

Gustavo Inzunza-Cervantes, Juan Ramón Herrera-Gavilanes, Josué Abisai Félix-Córdova, Luis Alejandro Padilla-Islas, José Manuel Ornelas-Aguirre, Víctor Adrián Cortés-García

{"title":"[Coronary artery disease multivessel not amenable to revascularization: contemporary cohort].","authors":"Gustavo Inzunza-Cervantes, Juan Ramón Herrera-Gavilanes, Josué Abisai Félix-Córdova, Luis Alejandro Padilla-Islas, José Manuel Ornelas-Aguirre, Víctor Adrián Cortés-García","doi":"10.5281/zenodo.11397136","DOIUrl":"10.5281/zenodo.11397136","url":null,"abstract":"Background: Severe diffuse coronary artery disease with anatomy that is not amenable to revascularization represents a poorly studied entity, with a poorly defined prognosis and prevalence, associated with high morbidity and mortality, poor quality of life and high hospitalization rates.Objective: Due to the limited evidence in this clinical field and the absence of contemporary studies, we decided to explore this line of research, determining epidemiological, clinical and prognostic aspects.Material and methods: Analytical, retrospective observational cohort study, carried out in a National Medical Center.Results: The prevalence of three-vessel coronary artery disease not susceptible to revascularization was 12.2%, the majority were men (66%), over 65 years of age, with a high burden of comorbidities: pharmacological management consisted of beta blockers (91.5 %), antiplatelet aggregation (95.3%) and statins (95.3%): cardiovascular mortality was 9.4%, with myocardial infarction occurring in 10.4%: the predictor variables of mortality were chronic kidney disease, age over 70 years, insufficiency mitral valve.Conclusion: Coronary artery disease of three vessels not susceptible to revascularization continues to be a frequent entity, with a high-risk clinical and anatomical profile, with a better contemporary prognosis despite the multiple gaps in knowledge that limit its understanding and treatment.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 4","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0