Revista medica del Instituto Mexicano del Seguro Social最新文献

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[BCL11B associated disorder a case report in Mexican population. Case report]. [墨西哥人群中 BCL11B 相关疾病的病例报告。 病例报告]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306819
Israel Enrique Crisanto-López, María Patricia Saldaña-Guerrer, Rosa María Hernández-Camacho, Dulce María Castro-Coyotl
{"title":"[BCL11B associated disorder a case report in Mexican population. Case report].","authors":"Israel Enrique Crisanto-López, María Patricia Saldaña-Guerrer, Rosa María Hernández-Camacho, Dulce María Castro-Coyotl","doi":"10.5281/zenodo.13306819","DOIUrl":"https://doi.org/10.5281/zenodo.13306819","url":null,"abstract":"<p><strong>Background: </strong>BCL11B variants are associated with intellectual developmental disorder with dysmorphic facies, speech delay, and T-cell abnormalities (IDDSFTA) (OMIN 618092). The clinical features include neurodevelopmental disorders (psychomotor delay, intellectual disability, language delay, autism spectrum features), facial dysmorphisms, immunological manifestations (asthma, allergies and T cells decrease). The aim is to present a IDDSFTA case in Mexican population with a probably pathogenic variant that has not been reported before and to compare it with literature cases.</p><p><strong>Clinic case: </strong>A 4-years-old male presents neurodevelopmental and language delay, healthy parents, non-consanguineous. He presents incomprehensible language, joint attention, plagiocephaly, bilateral epicanthus, short palpebral fissures, prominent tip nose, long and flat philtrum, Likert scale 4, thin lips, small mouth, dental crowding, hypodontia, borderline set ears, small nipples and teletelia. WES test reported a BCL11B gene, probably a pathogenic variant.</p><p><strong>Conclusions: </strong>In line with the information available, the detected variant has not been described before in literature; it is the first case reported of this pathology in the Mexican population. Patient's clinical features are IDDSFTA-like reported, which supports that this probable pathogenic variant is the etiology of the phenotype in our patient.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Use of ultrasound in vein of Galen malformation]. [超声波在 Galen 静脉畸形中的应用]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306799
Marisol De La Rosa-Alamilla, Rubí Chávez-Silva, Herminia Uscanga-Carrasco
{"title":"[Use of ultrasound in vein of Galen malformation].","authors":"Marisol De La Rosa-Alamilla, Rubí Chávez-Silva, Herminia Uscanga-Carrasco","doi":"10.5281/zenodo.13306799","DOIUrl":"10.5281/zenodo.13306799","url":null,"abstract":"<p><strong>Background: </strong>Aneurysmal malformation of the vein of Galen (AVMG) is a rare malformation of the intracranial venous system. The incidence is estimated at 1:10,000-25,0000 births. The clinical picture is very variable, in the neonatal period it includes seizures and heart failure. It is very difficult to diagnose, but by doing it in a timely manner, mortality is greatly reduced. It can be detected by prenatal ultrasounds and, at birth, the gold standard imaging study for its diagnosis is cerebral resonance and angioresonance. However, 50% of AVMG cannot be corrected and there is evidence that 77% of untreated cases result in death.</p><p><strong>Clinical case: </strong>The case of a newborn with a prenatal diagnosis is presented and at birth the diagnosis of MAVG was corroborated by neurosonography, and subsequently confirmed by venoresonance. His clinical evolution was documented, which included placement of a ventriculoperitoneal shunt and vascular embolization; however, there was a fatal outcome.</p><p><strong>Conclusions: </strong>In MAVG it is important to define the anatomy of the lesion, due to the clinical, therapeutic and prognostic implications that this represents. B-mode ultrasound, together with Doppler mode, are essential complementary tools for the diagnosis of AVMG, as well as for prognostic evaluation and to provide information for counseling parents and for optimal management. Successful treatment remains a complex therapeutic challenge.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Risk of postoperative delirium in older adults under balanced general anesthesia]. [平衡全身麻醉下老年人术后谵妄的风险]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13381460
Basilia Anabel Cahuich-Rodríguez, Arlene Guadalupe Acosta-Mass, Héctor Isaac Rocha-González
{"title":"[Risk of postoperative delirium in older adults under balanced general anesthesia].","authors":"Basilia Anabel Cahuich-Rodríguez, Arlene Guadalupe Acosta-Mass, Héctor Isaac Rocha-González","doi":"10.5281/zenodo.13381460","DOIUrl":"10.5281/zenodo.13381460","url":null,"abstract":"<p><strong>Background: </strong>Anesthetic depth can influence the incidence of postoperative delirium (POD). This depth is related to the potency of the volatile anesthetics used to maintain balanced general anesthesia. This potency is measured by means of the minimum alveolar concentration (MAC). In older adults, it is unknown which MAC is associated with the risk of POD.</p><p><strong>Objective: </strong>To estimate the risk of POD associated with minimum alveolar concentration (MAC) levels of volatile anesthetics in older adults who received balanced general anesthesia.</p><p><strong>Material and methods: </strong>A prospective cohort study was carried out with 119 patients, aged ≥ 60 years, with 0 points in the 4 \"As\" test (4AT), without neurological or psychiatric diseases. During the intraoperative period, the CAM provided was recorded, and in the postoperative period, the presence of emergency with delirium and/or POD was evaluated at 2 and 24 hours, considering a score ≥ 4.</p><p><strong>Results: </strong>A longer hospital stay was found in the group that received a MAC ≥0.9. The incidence of POD was 29.4%. Those who received a MAC ≥ 0.9 had an RR of 2.22 (95%CI: 1.2-4.2) of presenting POD. An adjusted logistic regression model was performed with the variables female sex (OR: 4, 95%CI: 1.5-10.4), ASA physical status 3-4 (OR: 3.7, 95%CI: 1.5-9) and MAC ≥ 0.9 (OR: 3.1 95%CI: 1.2-8) with an R2: 0.26 and a constant of 3.005.</p><p><strong>Conclusions: </strong>MAC ≥ 0.9 represents a risk factor for DPO, so individualized dosing of volatile anesthetics should be used.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Avian influenza: a latent challenge]. [禽流感:潜伏的挑战]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.12668094
David Alejandro Cabrera-Gaytán
{"title":"[Avian influenza: a latent challenge].","authors":"David Alejandro Cabrera-Gaytán","doi":"10.5281/zenodo.12668094","DOIUrl":"10.5281/zenodo.12668094","url":null,"abstract":"<p><p>The avian influenza virus was first identified in China in 1996, but it was in 2021 when numerous outbreaks of avian influenza began in different regions of the world, including Mexico. This virus has caused a significant impact on animal health and well-being, since it mainly affects wild birds, poultry and other animals, including humans, putting the food security and subsistence of those who depend on it at risk.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142684120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Epidemiological and clinical aspects of Guilain-Barré syndrome, 2012-2022]. [吉兰-巴雷综合征的流行病学和临床方面,2012-2022 年]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306747
Coltzinc Hazael Hernández-Jardón, Leora Velásquez-Pérez
{"title":"[Epidemiological and clinical aspects of Guilain-Barré syndrome, 2012-2022].","authors":"Coltzinc Hazael Hernández-Jardón, Leora Velásquez-Pérez","doi":"10.5281/zenodo.13306747","DOIUrl":"10.5281/zenodo.13306747","url":null,"abstract":"<p><strong>Background: </strong>Guillain-Barré syndrome (GBS) is an immune-mediated polyradiculoneuropathy, generally post-infectious, and is the leading cause of acute flaccid paralysis worldwide.</p><p><strong>Objective: </strong>To describe the epidemiological, clinical and behavioral characteristics of Guillain-Barré syndrome.</p><p><strong>Material and methods: </strong>An observational, cross-sectional and descriptive study was carried out. The records of all patients with GBS from 2012-2022 were reviewed, and information on epidemiological and clinical variables was obtained. The incidence was calculated for each of the study years and the trend for the study period using the Pearson correlation coefficient, considering p ≤ 0.05 statistically significant.</p><p><strong>Results: </strong>A total of 477 cases were obtained, 67% were men, among the comorbidities, drug addictions were present in 31% of the cases. Most cases were preceded by a gastrointestinal infectious condition. The most common phenotype was acute motor axonal neuropathy. 29% showed up in summer. A statistically significant tendency to increase was observed (p ≤ 0.05) and a mortality of 2.5% with predominance in the axonal variety.</p><p><strong>Conclusions: </strong>The results of this study cover a relatively long period compared to other reviews, the findings agree with previous studies. GBS showed a statistically significant tendency to increase.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Arrhythmia as the first symptom of neonatal cardiac tumors: Case report]. [心律失常是新生儿心脏肿瘤的首发症状:病例报告]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306836
Óscar Andrés Ramírez-Terán, Eduardo Tomás-Alvarado
{"title":"[Arrhythmia as the first symptom of neonatal cardiac tumors: Case report].","authors":"Óscar Andrés Ramírez-Terán, Eduardo Tomás-Alvarado","doi":"10.5281/zenodo.13306836","DOIUrl":"https://doi.org/10.5281/zenodo.13306836","url":null,"abstract":"<p><strong>Background: </strong>Neonatal cardiac tumors are a rare pathology, with an approximate incidence of 0.017% in autopsies and 0.31% in obstetric echographies. The most common primary cardiac tumor is rhabdomyomas and its clinical manifestations are highly variable. Most patients do not require therapeutic management unless there is hemodynamic compromise, in which one option is surgical management, which implies high mortality. Rhabdomyomas are usually associated with tuberous sclerosis, a disease for which drugs such as everolimus or sirolimus have been used.</p><p><strong>Clinical case: </strong>Newborn male patient with no significant history, in whom a cardiac arrhythmia was detected during the routine physical examination. After the evaluation by Pediatric Cardiology, it was determined that the patient had supraventricular extrasystoles, in addition to multiple intracardiac masses that, due to imaging characteristics, were compatible with rhabdomyomas, so it was determined that the cause of cardiac arrhythmia was the presence of multiple tumors. Due to the condition of the conduction system, everolimus and propranolol were used. After 7 days, control of the arrhythmias was achieved and resolution of the tumors was achieved after 8 weeks.</p><p><strong>Conclusions: </strong>Rhabdomyomas are cardiac tumors associated with tuberous sclerosis, clinical complications can be managed effectively with everolimus as in the case presented.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[HIV mortality trends in Mexico, 2000-2022]. [墨西哥艾滋病毒死亡率趋势,2000-2022 年]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306693
Oswaldo Sinoe Medina-Gómez, Antonio Barrios-Pérez, Arturo Sosa-Tapia, Irving Díaz-Muñoz
{"title":"[HIV mortality trends in Mexico, 2000-2022].","authors":"Oswaldo Sinoe Medina-Gómez, Antonio Barrios-Pérez, Arturo Sosa-Tapia, Irving Díaz-Muñoz","doi":"10.5281/zenodo.13306693","DOIUrl":"https://doi.org/10.5281/zenodo.13306693","url":null,"abstract":"<p><strong>Background: </strong>About 39 million people are living with HIV worldwide, 62% of people living with HIV receive antiretroviral therapy. The combination of ART has allowed suppression of viral replication and disease progression, decreasing mortality.</p><p><strong>Objective: </strong>To analyze HIV trends in Mexico during the period 2000-2022.</p><p><strong>Material and methods: </strong>An ecological study of deaths due to HIV during the period 2000 to 2022 was carried out. Mortality rates were adjusted by the direct method and joinpoint regression was used to analyze trends and estimate the annual percentage change.</p><p><strong>Results: </strong>The national HIV mortality rate was 0.05 per 100,000 population while in 2022 it decreased to 0.04 per 100,000 population. Trend analysis identified two points of change, with a significant reduction in mortality rates at the national level in the period 2007-2022 and a subsequent decrease in mortality. At the state level, there were variations in trends with some states showing significant increases at the end of the study period, such as Jalisco, Campeche, and Quintana Roo. Changes by sex were heterogeneous.</p><p><strong>Conclusions: </strong>Reductions in HIV mortality rates are limited to some states of the country, so it is necessary to implement health strategies according to social, economic, and cultural characteristics and with a gender perspective.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Emerging roles of neutrophils in the prognosis of colorectal cancer]. [中性粒细胞在结直肠癌预后中的新作用]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306792
Alejandra Mantilla, María de Lourdes Ramírez-Ramírez, Antonio Jorge Berlanga-Taylor, Eduardo Vadillo
{"title":"[Emerging roles of neutrophils in the prognosis of colorectal cancer].","authors":"Alejandra Mantilla, María de Lourdes Ramírez-Ramírez, Antonio Jorge Berlanga-Taylor, Eduardo Vadillo","doi":"10.5281/zenodo.13306792","DOIUrl":"10.5281/zenodo.13306792","url":null,"abstract":"<p><p>Colorectal cancer (CRC) is one of the most frequent and lethal cancers in Mexico and the world. It is noteworthy that globally, the incidence of CRC is increasing at a rate of 2% per year in patients younger than 50 years of age. Its early detection, primarily based on colonoscopy screening starting at 45 years of age, is an essential weapon to reduce its mortality. When CRC is detected, the treatment is surgical; however, the pathology reports and biomedical research on the tumor microenvironment may offer new parameters that could serve as prognostic biomarkers. In this respect, the presence or absence of neutrophils associated with neoplastic tissues may indicate their prognostic relevance for the disease. Although this field is still controversial, our recently published evidence suggests that the presence of neutrophils with an anti-tumoral phenotype, particularly at the invasive margin of the colon tumors, could indicate a favorable prognosis. This emerging information suggests that the characterization of immune cells, particularly neutrophils, could contribute to assessing the evolution of CRC and identifying patients at increased risk of recurrences. In this article, we discuss relevant points that should be addressed when interpreting neutrophil-related data in the context of CRC.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Characteristics of melanoma in Mexicans seen at "La Raza" National Medical Center]. [在 "La Raza "国家医疗中心就诊的墨西哥人中黑色素瘤的特征]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306762
Blanca Carlos-Ortega, Ulises Ángeles-Garay, Marian Fernández-Martínez, Guillermo Gómez-Campos, Rodrigo Roldán-Marín
{"title":"[Characteristics of melanoma in Mexicans seen at \"La Raza\" National Medical Center].","authors":"Blanca Carlos-Ortega, Ulises Ángeles-Garay, Marian Fernández-Martínez, Guillermo Gómez-Campos, Rodrigo Roldán-Marín","doi":"10.5281/zenodo.13306762","DOIUrl":"10.5281/zenodo.13306762","url":null,"abstract":"<p><strong>Background: </strong>Melanoma is the third most common type of skin cancer in Mexico and represents 75% of skin cancer deaths. Dermoscopy is a diagnostic tool that increases early detection of melanoma compared to naked eye examination.</p><p><strong>Objective: </strong>The aim of this study was to describe the clinical, dermoscopic and histological characteristics of patients with a confirmed diagnosis of cutaneous melanoma treated at the \"La Raza\" National Medical Center.</p><p><strong>Material and methods: </strong>A retrospective, descriptive and cross-sectional study was carried out from March 1998 to December 2013, with 187 histologically confirmed cases, considering: sex, age, skin phototype, history, topography of the lesion, dermoscopic pattern, metastasis at the time of diagnosis and histological subtype, Breslow index and Clark index, using the chi-square test as a non-parametric statistical method to analyze the data obtained.</p><p><strong>Results: </strong>Most patients had skin phototype III and the most affected location was the lower limb. Clinically, acral lentiginous melanomas and nodular melanomas were the most observed. The most common dermoscopic finding was the multicomponent pattern. Clinically and histologically, the most frequent subtype associated with metastasis was nodular melanoma. Acral lentiginous melanoma was more common among patients without metastasis.</p><p><strong>Conclusions: </strong>Unfortunately, melanoma is still diagnosed in advanced stages in Mexico; for its early recognition, training in the use of dermoscopy and greater awareness about melanoma in the Mexican population must be encouraged.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142684121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Clostridiodes difficile bacteraemia. First mexican case report]. [难辨梭状芽孢杆菌菌血症:墨西哥首例报告]。
Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306825
Iván González-Godínez, Edgar Carrillo-Vázquez, Ana Laura Garduño-Ortíz, Sebastián Enrique Chacón-Hernández, Homero Antonio Hevia-Del Cabrera
{"title":"[Clostridiodes difficile bacteraemia. First mexican case report].","authors":"Iván González-Godínez, Edgar Carrillo-Vázquez, Ana Laura Garduño-Ortíz, Sebastián Enrique Chacón-Hernández, Homero Antonio Hevia-Del Cabrera","doi":"10.5281/zenodo.13306825","DOIUrl":"https://doi.org/10.5281/zenodo.13306825","url":null,"abstract":"<p><strong>Background: </strong>Clostridiodes difficile bacteremia (CDB) develops in less than 1% of all the cases, nonetheless, with a significant increase in mortality. The objective of the present article is to report the first case of CDB in the Mexican population, empathizing with the treatment difficulty derived from the lack of consensus.</p><p><strong>Clinical case: </strong>A 42-year-old female with previous history of chronic thromboembolic pathologies and grade III obesity, develops community acquired atypical pneumonia requiring hospitalization, having parenteral antibiotics. During hospitalization, non severe C. difficile infection was concluded and started treatment with Vancomycin for 10 days. One week later the patient presented to the emergency department at HES CMN SXXI with gastrointestinal symptomatology, mostly epigastric pain, fever and diarrhea. After proper approach, C. difficile was isolated in blood cultures through mass spectrophotometry analysis, for which a 10-day treatment of metronidazole was prescribed with resolution of the infection being discharged afterwards.</p><p><strong>Conclusions: </strong>CDB is an exceptional and lethal clinical condition, mainly seen in patients with previous gastrointestinal diseases. IV Metronidazole demonstrated therapeutic efficacy in this case report and could be a successful and available therapeutic option in Mexican health care units.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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