Revista medica del Instituto Mexicano del Seguro Social最新文献

[Detection of circulating tumor cells in women with early breast cancer]. [检测早期乳腺癌妇女体内的循环肿瘤细胞]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306736

Eunice López-Muñoz, José Eduardo Márquez-García, Angélica Moncada-Morales, Coral García-Rivera, Miguel Ángel López-Valle, Arturo Aguilar Rojas

{"title":"[Detection of circulating tumor cells in women with early breast cancer].","authors":"Eunice López-Muñoz, José Eduardo Márquez-García, Angélica Moncada-Morales, Coral García-Rivera, Miguel Ángel López-Valle, Arturo Aguilar Rojas","doi":"10.5281/zenodo.13306736","DOIUrl":"10.5281/zenodo.13306736","url":null,"abstract":"Background: There are multiple methods and biomarkers with different detection rates to circulating tumor cells (CTCs) in women with breast cancer (BC). However, to the best our knowledge, no study has been carried out to detect CTCs in women with early BC in Mexico.Objective: Calculate the detection rate of CTCs in peripheral blood of Mexican women with early BC by quantification of the relative expression of KRT19, MUC1 and SCGB2A2.Material and methods: Observational, longitudinal, analytical study, which included 62 Mexican women, over 18 years of age, with BC clinical stage 0, I and II. Cells with a density < 1.077 g/ml were isolated from 4 mL of peripheral blood obtained 24 h before surgery, RNAS was extracted and RT-qPCR was performed to quantify the relative expression of KRT19, MUC1 and SCGB2A2.Results: The diagnosis of BC was confirmed in the definitive pathological study in 59 women. 1 case (1.7%), expressed KRT19, 18 cases (30.5%) MUC1, 2 cases (3.4%) SCGB2A2, and 19 cases (32.2%) expressed at least one of the three biomarkers.Conclusions: CTCs detection rates were like those reported in other populations when MUC1 was used, but lower when KRT19 and SCGB2A2 were used. Standardization of blood sample collection and processing, as well as biomarker expression analysis, is important to reduce variability in the detection of CTCs in specific populations.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142684111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Erythrocyte morphological alterations as predictors of kidney injury severity]. [红细胞形态学改变作为肾损伤严重程度的预测指标]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306729

Azucena Cruz-Balbuena, Leticia Piedras-Reyes, Juan Carlos Sánchez-Serrano, Maricruz Meneses-Angel, José Luis Rubio-Cruz, Alexis Yael Fernández-Rivera

{"title":"[Erythrocyte morphological alterations as predictors of kidney injury severity].","authors":"Azucena Cruz-Balbuena, Leticia Piedras-Reyes, Juan Carlos Sánchez-Serrano, Maricruz Meneses-Angel, José Luis Rubio-Cruz, Alexis Yael Fernández-Rivera","doi":"10.5281/zenodo.13306729","DOIUrl":"https://doi.org/10.5281/zenodo.13306729","url":null,"abstract":"Background: Chronic kidney disease (CKD) is characterized by decreased renal function. Detecting and treating CKD in its early stages is essential for prognosis and use of less invasive renal treatments. CKD can manifest with different markers of renal damage. However, few studies evaluate the presence of erythrocyte morphological changes in the peripheral blood of patients with CKD.Objective: To evaluate the correlation between erythrocyte morphological changes and KDIGO stage as a predictor of the severity of renal damage.Material and methods: A descriptive, prospective, cross-sectional, and correlational study of patients admitted between March and April 2023. Qualitative variables were reported as frequencies and percentages, and quantitative variables were reported by central tendency and dispersion measures. Finally, Spearman correlation was performed between erythrocyte morphological alterations and the KDIGO stage in patients with CKD.Results: A total of 385 patients were included, and the correlation of the number of erythrocyte morphological alterations with the KDIGO stage showed that it is directly proportional in a significant way (Spearman's ρ 0.489, p < 0.0001). It was higher for anisocytosis.Conclusions: Erythrocyte morphological alterations in patients with CKD are frequent and could be a predictor of the severity of this disease.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Clinical, demographic and histopathological characteristics of individuals with Kaposi's sarcoma and living with HIV in Mexico]. [墨西哥卡波西肉瘤患者和艾滋病毒感染者的临床、人口统计学和组织病理学特征]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306755

Melissa Lomelí-Canedo, Beatriz de Guadalupe Pizano-Márquez, Mario Magaña-García

{"title":"[Clinical, demographic and histopathological characteristics of individuals with Kaposi's sarcoma and living with HIV in Mexico].","authors":"Melissa Lomelí-Canedo, Beatriz de Guadalupe Pizano-Márquez, Mario Magaña-García","doi":"10.5281/zenodo.13306755","DOIUrl":"10.5281/zenodo.13306755","url":null,"abstract":"Background: Kaposi's sarcoma (KS) is the most frequent cancer in HIV-positive people in developing countries, affecting their quality of life.Objective: To analyze the clinical, histopathological and epidemiological features of KS in patients living with HIV, as well as to evaluate the impact of antiretroviral treatment on the incidence and progression of the disease.Material and methods: Observational, descriptive, retrospective and cohort study. During October 2022 to August 2023. Twenty-eight HIV-positive male patients were included and were diagnosed with KS in our institution. Clinical variables, CD4+ cell counts, viral load and treatments received were evaluated, in addition to histopathological and immunohistochemical analysis of the lesions.Results: Most patients had low CD4+ cell counts and high viral load at diagnosis. The most common lesions were erythematous-violaceous papules, nodules and and plaques, in multiple areas of the body. HHV8 was identified in most cases. Antiretroviral therapy showed a long-term protective effect on the incidence of KS. Opportunistic infections were frequent in these patients, the most common one was tuberculosis.Conclusions: Our study highlights the need for an early and multidisciplinary approach in the management of KS in HIV-positive patients, underlining the importance of antiretroviral treatment to prevent disease progression. Furthermore, it stresses its complexity and the significant prevalence of opportunistic infections, advocating for comprehensive strategies addressing sarcoma as well as concomitant infections.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142684122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Grip strength and high blood pressure: a case-control study]. [握力与高血压：一项病例对照研究]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13323291

Martha Beatriz Bustamante-Hernández, José de Jesús Garduño-García, Elías Cardoso-Pena, Laura Montenegro-Morales, Eneida Camarillo-Romero, Gabriel Gerardo Huitrón-Bravo, Socorro Camarillo-Romero

{"title":"[Grip strength and high blood pressure: a case-control study].","authors":"Martha Beatriz Bustamante-Hernández, José de Jesús Garduño-García, Elías Cardoso-Pena, Laura Montenegro-Morales, Eneida Camarillo-Romero, Gabriel Gerardo Huitrón-Bravo, Socorro Camarillo-Romero","doi":"10.5281/zenodo.13323291","DOIUrl":"10.5281/zenodo.13323291","url":null,"abstract":"Introduction: Introduction: Low hand grip strength (HGS) is one of the criteria for diagnosing frailty and sarcopenia, it is associated with the risk of metabolic and mental diseases; Studies have shown that in patients with arterial hypertension (BP), low HGS represents a risk of incidence of cardiovascular disease and mortality, in addition to mortality from other causes; however, there are still no conclusive studies regarding the factors that determine HGS in BP.Objective: Identify the factors that influence low HGS in patients with BP.Material and methods: Cross-sectional, observational, analytical case-control study. 100 patients with a diagnosis and treatment of HTN were included, and 100 controls matched by age and sex. Demographic data, self-report of physical activity, weight, height, body composition, and HGS were obtained. Descriptive statistics, Chi-square, were performed to look for differences in means, Mann-Whitney U, Kruskal-Wallis, and Games-Howell post-hoc analysis. In all tests, a 95% confidence interval (95%CI) was considered.Results: The average age of the sample was 47.40 ± 0.54; The results of body composition between the study groups did not show statistically significant differences; However, when looking for difference in means between tertiles of relative strength for the elements of body composition, different factors were found that influence HGS.Conclusions: Body composition is what determines HGS in patients between 30 and 60 years of age, however in patients with BP it is visceral fat that is responsible for low HGS.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Workplace violence as a predictor of suicidal ideation in undergraduate internal physicians]. [工作场所暴力是本科内科医生自杀倾向的预测因素]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306721

Moisés Omar Ayala-Burboa, Raquel García-Flores, Teresa Iveth Sotelo-Quiñonez, Christian Oswaldo Acosta-Quiroz

{"title":"[Workplace violence as a predictor of suicidal ideation in undergraduate internal physicians].","authors":"Moisés Omar Ayala-Burboa, Raquel García-Flores, Teresa Iveth Sotelo-Quiñonez, Christian Oswaldo Acosta-Quiroz","doi":"10.5281/zenodo.13306721","DOIUrl":"https://doi.org/10.5281/zenodo.13306721","url":null,"abstract":"Introduction: The environments in which doctors in training operate have been distinguished by being rigid, hostile and routine. There is scientific evidence that people who are victims of workplace violence are more likely to suffer from depression, a disorder that has been associated with suicidal ideation.Objective: To predict suicidal ideation as a function of depressive symptoms and workplace violence in undergraduate internal physicians.Material and methods: The quantitative method was used through a non-experimental, cross-sectional, explanatory design with non-probabilistic convenience sampling. 117 medical students who were doing their internship in health centers in Sonora, Mexico participated. Participants responded to the Workplace Violence Scale (Mobbing), the Beck Depression Inventory, and the Beck Suicidal Ideation Scale.Results: A high perception of workplace violence, moderate levels of depression and low levels of suicidal ideation were identified; Workplace violence was positively and significantly associated with depression and suicidal behavior. Furthermore, it was found that violence provides more explanation for suicidal behavior compared to depression.Conclusions: The predictive role of workplace violence in the suicidal behavior of undergraduate internal physicians is confirmed. Highlights the importance of developing prevention and intervention programs to reduce workplace violence in medical training environments.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[BCL11B associated disorder a case report in Mexican population. Case report]. [墨西哥人群中 BCL11B 相关疾病的病例报告。病例报告]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306819

Israel Enrique Crisanto-López, María Patricia Saldaña-Guerrer, Rosa María Hernández-Camacho, Dulce María Castro-Coyotl

{"title":"[BCL11B associated disorder a case report in Mexican population. Case report].","authors":"Israel Enrique Crisanto-López, María Patricia Saldaña-Guerrer, Rosa María Hernández-Camacho, Dulce María Castro-Coyotl","doi":"10.5281/zenodo.13306819","DOIUrl":"https://doi.org/10.5281/zenodo.13306819","url":null,"abstract":"Background: BCL11B variants are associated with intellectual developmental disorder with dysmorphic facies, speech delay, and T-cell abnormalities (IDDSFTA) (OMIN 618092). The clinical features include neurodevelopmental disorders (psychomotor delay, intellectual disability, language delay, autism spectrum features), facial dysmorphisms, immunological manifestations (asthma, allergies and T cells decrease). The aim is to present a IDDSFTA case in Mexican population with a probably pathogenic variant that has not been reported before and to compare it with literature cases.Clinic case: A 4-years-old male presents neurodevelopmental and language delay, healthy parents, non-consanguineous. He presents incomprehensible language, joint attention, plagiocephaly, bilateral epicanthus, short palpebral fissures, prominent tip nose, long and flat philtrum, Likert scale 4, thin lips, small mouth, dental crowding, hypodontia, borderline set ears, small nipples and teletelia. WES test reported a BCL11B gene, probably a pathogenic variant.Conclusions: In line with the information available, the detected variant has not been described before in literature; it is the first case reported of this pathology in the Mexican population. Patient's clinical features are IDDSFTA-like reported, which supports that this probable pathogenic variant is the etiology of the phenotype in our patient.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Use of ultrasound in vein of Galen malformation]. [超声波在 Galen 静脉畸形中的应用]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306799

Marisol De La Rosa-Alamilla, Rubí Chávez-Silva, Herminia Uscanga-Carrasco

{"title":"[Use of ultrasound in vein of Galen malformation].","authors":"Marisol De La Rosa-Alamilla, Rubí Chávez-Silva, Herminia Uscanga-Carrasco","doi":"10.5281/zenodo.13306799","DOIUrl":"10.5281/zenodo.13306799","url":null,"abstract":"Background: Aneurysmal malformation of the vein of Galen (AVMG) is a rare malformation of the intracranial venous system. The incidence is estimated at 1:10,000-25,0000 births. The clinical picture is very variable, in the neonatal period it includes seizures and heart failure. It is very difficult to diagnose, but by doing it in a timely manner, mortality is greatly reduced. It can be detected by prenatal ultrasounds and, at birth, the gold standard imaging study for its diagnosis is cerebral resonance and angioresonance. However, 50% of AVMG cannot be corrected and there is evidence that 77% of untreated cases result in death.Clinical case: The case of a newborn with a prenatal diagnosis is presented and at birth the diagnosis of MAVG was corroborated by neurosonography, and subsequently confirmed by venoresonance. His clinical evolution was documented, which included placement of a ventriculoperitoneal shunt and vascular embolization; however, there was a fatal outcome.Conclusions: In MAVG it is important to define the anatomy of the lesion, due to the clinical, therapeutic and prognostic implications that this represents. B-mode ultrasound, together with Doppler mode, are essential complementary tools for the diagnosis of AVMG, as well as for prognostic evaluation and to provide information for counseling parents and for optimal management. Successful treatment remains a complex therapeutic challenge.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142690182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Risk of postoperative delirium in older adults under balanced general anesthesia]. [平衡全身麻醉下老年人术后谵妄的风险]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13381460

Basilia Anabel Cahuich-Rodríguez, Arlene Guadalupe Acosta-Mass, Héctor Isaac Rocha-González

{"title":"[Risk of postoperative delirium in older adults under balanced general anesthesia].","authors":"Basilia Anabel Cahuich-Rodríguez, Arlene Guadalupe Acosta-Mass, Héctor Isaac Rocha-González","doi":"10.5281/zenodo.13381460","DOIUrl":"10.5281/zenodo.13381460","url":null,"abstract":"Background: Anesthetic depth can influence the incidence of postoperative delirium (POD). This depth is related to the potency of the volatile anesthetics used to maintain balanced general anesthesia. This potency is measured by means of the minimum alveolar concentration (MAC). In older adults, it is unknown which MAC is associated with the risk of POD.Objective: To estimate the risk of POD associated with minimum alveolar concentration (MAC) levels of volatile anesthetics in older adults who received balanced general anesthesia.Material and methods: A prospective cohort study was carried out with 119 patients, aged ≥ 60 years, with 0 points in the 4 \"As\" test (4AT), without neurological or psychiatric diseases. During the intraoperative period, the CAM provided was recorded, and in the postoperative period, the presence of emergency with delirium and/or POD was evaluated at 2 and 24 hours, considering a score ≥ 4.Results: A longer hospital stay was found in the group that received a MAC ≥0.9. The incidence of POD was 29.4%. Those who received a MAC ≥ 0.9 had an RR of 2.22 (95%CI: 1.2-4.2) of presenting POD. An adjusted logistic regression model was performed with the variables female sex (OR: 4, 95%CI: 1.5-10.4), ASA physical status 3-4 (OR: 3.7, 95%CI: 1.5-9) and MAC ≥ 0.9 (OR: 3.1 95%CI: 1.2-8) with an R2: 0.26 and a constant of 3.005.Conclusions: MAC ≥ 0.9 represents a risk factor for DPO, so individualized dosing of volatile anesthetics should be used.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Arrhythmia as the first symptom of neonatal cardiac tumors: Case report]. [心律失常是新生儿心脏肿瘤的首发症状：病例报告]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306836

Óscar Andrés Ramírez-Terán, Eduardo Tomás-Alvarado

{"title":"[Arrhythmia as the first symptom of neonatal cardiac tumors: Case report].","authors":"Óscar Andrés Ramírez-Terán, Eduardo Tomás-Alvarado","doi":"10.5281/zenodo.13306836","DOIUrl":"https://doi.org/10.5281/zenodo.13306836","url":null,"abstract":"Background: Neonatal cardiac tumors are a rare pathology, with an approximate incidence of 0.017% in autopsies and 0.31% in obstetric echographies. The most common primary cardiac tumor is rhabdomyomas and its clinical manifestations are highly variable. Most patients do not require therapeutic management unless there is hemodynamic compromise, in which one option is surgical management, which implies high mortality. Rhabdomyomas are usually associated with tuberous sclerosis, a disease for which drugs such as everolimus or sirolimus have been used.Clinical case: Newborn male patient with no significant history, in whom a cardiac arrhythmia was detected during the routine physical examination. After the evaluation by Pediatric Cardiology, it was determined that the patient had supraventricular extrasystoles, in addition to multiple intracardiac masses that, due to imaging characteristics, were compatible with rhabdomyomas, so it was determined that the cause of cardiac arrhythmia was the presence of multiple tumors. Due to the condition of the conduction system, everolimus and propranolol were used. After 7 days, control of the arrhythmias was achieved and resolution of the tumors was achieved after 8 weeks.Conclusions: Rhabdomyomas are cardiac tumors associated with tuberous sclerosis, clinical complications can be managed effectively with everolimus as in the case presented.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[HIV mortality trends in Mexico, 2000-2022]. [墨西哥艾滋病毒死亡率趋势，2000-2022 年]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2024-11-04 DOI: 10.5281/zenodo.13306693

Oswaldo Sinoe Medina-Gómez, Antonio Barrios-Pérez, Arturo Sosa-Tapia, Irving Díaz-Muñoz

{"title":"[HIV mortality trends in Mexico, 2000-2022].","authors":"Oswaldo Sinoe Medina-Gómez, Antonio Barrios-Pérez, Arturo Sosa-Tapia, Irving Díaz-Muñoz","doi":"10.5281/zenodo.13306693","DOIUrl":"https://doi.org/10.5281/zenodo.13306693","url":null,"abstract":"Background: About 39 million people are living with HIV worldwide, 62% of people living with HIV receive antiretroviral therapy. The combination of ART has allowed suppression of viral replication and disease progression, decreasing mortality.Objective: To analyze HIV trends in Mexico during the period 2000-2022.Material and methods: An ecological study of deaths due to HIV during the period 2000 to 2022 was carried out. Mortality rates were adjusted by the direct method and joinpoint regression was used to analyze trends and estimate the annual percentage change.Results: The national HIV mortality rate was 0.05 per 100,000 population while in 2022 it decreased to 0.04 per 100,000 population. Trend analysis identified two points of change, with a significant reduction in mortality rates at the national level in the period 2007-2022 and a subsequent decrease in mortality. At the state level, there were variations in trends with some states showing significant increases at the end of the study period, such as Jalisco, Campeche, and Quintana Roo. Changes by sex were heterogeneous.Conclusions: Reductions in HIV mortality rates are limited to some states of the country, so it is necessary to implement health strategies according to social, economic, and cultural characteristics and with a gender perspective.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"62 6","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0