Eduardo Amezola-Herrera, Lucy Vania Galindo-Pacheco, Gloria Patricia Sosa-Bustamante, Carlos Paque-Bautista, Alejandro Moctezuma-Paz, Alma Patricia González
{"title":"[Sleep disorders associated with montelukast in children with respiratory allergy].","authors":"Eduardo Amezola-Herrera, Lucy Vania Galindo-Pacheco, Gloria Patricia Sosa-Bustamante, Carlos Paque-Bautista, Alejandro Moctezuma-Paz, Alma Patricia González","doi":"10.5281/zenodo.21462729","DOIUrl":"10.5281/zenodo.21462729","url":null,"abstract":"<p><strong>Background: </strong>Asthma and allergic rhinitis are the most common respiratory allergic disorders in the Mexican population. Montelukast is a leukotriene receptor antagonist that has been widely used in these conditions. An association has been documented with the onset and modification of multiple sleep disorders, as well as other neuropsychiatric alterations in pediatric population.</p><p><strong>Objective: </strong>To analyze the association between montelukast and sleep disorders in children with respiratory allergies.</p><p><strong>Material and methods: </strong>A prospective and analytical cohort study was conducted. Patients aged 5 to 17 years diagnosed with asthma and allergic rhinitis were recruited from a third-level hospital. They were divided into 2 groups: a montelukast user group and a control group. Patients who withdrew their consent or did not complete the questionnaires were excluded.</p><p><strong>Results: </strong>120 children were analyzed, 60 children using montelukast and 60 not using it. The median age was 9 and 10 years, respectively. Five (4.17%) of the children had asthma as their primary diagnosis, 60 (50%) had allergic rhinitis, and 55 (45.83%) had both asthma and allergic rhinitis. Among the children taking montelukast, 46 (73.02%) had sleep disorders, compared to 17 (14.17%) of those not taking montelukast. The association showed an odds ratio (OR) of 8.31, p < 0.0001.</p><p><strong>Conclusion: </strong>Montelukast use was associated with the presence of sleep disorders in the studied population.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7135"},"PeriodicalIF":0.0,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614669/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Fernanda Mendoza-Rangel, Esmeralda Campos-Aguirre, Gamaliel Benítez-Arvizu
{"title":"[Effectiveness of donor selection in a blood bank].","authors":"María Fernanda Mendoza-Rangel, Esmeralda Campos-Aguirre, Gamaliel Benítez-Arvizu","doi":"10.5281/zenodo.21462833","DOIUrl":"10.5281/zenodo.21462833","url":null,"abstract":"<p><p>Transfusion safety in Mexico depends on 2 essential pillars: The proper clinical selection of donors and the effective application of screening tests established in current regulations. Among these tests, it is included mandatory detection of human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), as well as Trypanosoma cruzi and Treponema pallidum, all considered highly relevant pathogens due to their potential for bloodborne transmission and their clinical impact. Each year, thousands of people in the country acquire HCV, HBV, or HIV infections, and a significant proportion develop chronic complications that can lead to death. Given that current regulations have not been updated since 2012 and the proposed 2024 revision has not yet been approved, it is crucial to know which viruses might be present in apparently healthy donors despite the screening tests already performed on them. In this context, in this opinion article the effectiveness of donor selection and screening strategies was analyzed using the findings of an international collaborative study that analyzed pooled samples through massive parallel sequencing. Encouragingly, no traces of HIV, HBV, or HCV were detected, which suggests a favorable outlook for transfusion safety and supports the effectiveness of the procedures implemented at the National Medical Center's Blood Bank.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7035"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13600742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gerardo Rivera-Silva, María Guadalupe Moreno-Treviño, Claudia Cristina Santos-Lozan, Pablo Martínez-Fernández
{"title":"[Artificial intelligence and cardiovascular biobanks: Shared technological promise and ethical responsibility].","authors":"Gerardo Rivera-Silva, María Guadalupe Moreno-Treviño, Claudia Cristina Santos-Lozan, Pablo Martínez-Fernández","doi":"10.5281/zenodo.21462818","DOIUrl":"10.5281/zenodo.21462818","url":null,"abstract":"<p><p>The implementation of artificial intelligence (AI) in biobanks and cardiovascular tissue banks constitutes a structural transformation with a significant impact on precision medicine, translational research, and the management of biomedical resources. These technologies enable the optimization, storage, and allocation of tissue classification, improve sample traceability, and allow the integrated analysis of large volumes of clinical, histological, and genomic data. However, their adoption introduces ethical, technical, and epistemological challenges that go beyond a purely instrumental perspective. The use of algorithms in clinical contexts poses risks such as excessive automation, the opacity of predictive models, the reproduction of biases, breaches of donor privacy, and the handling of sensitive genomic data. In addition, increasing reliance on automated systems may displace expert judgment and generate a false perception of objectivity. This article analyzes these implications and proposes a framework for the responsible implementation of AI in cardiovascular biobanks, based on principles of equity, transparency, data governance, clinical applicability, and respect for autonomy, emphasizing that their value depends on their ethical and scientific robustness. All of this is aimed at strengthening social trust, scientific quality, and sustainable clinical benefit.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7068"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13610888/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Professionalization of medical education: Axes and strategies for excellence].","authors":"Gilberto Guzmán Valdivia-Gómez","doi":"10.5281/zenodo.21462851","DOIUrl":"10.5281/zenodo.21462851","url":null,"abstract":"<p><p>The professionalization of medical education is an essential, strategic renewal movement, driven by the need to graduate competent, ethical physicians who meet the demands of healthcare systems. This paradigm is structured around 3 interdependent axes: medical professionalism development (student), competency-based education (CBE) (institution), and medical faculty professionalization. The most advanced curricular model recommended is Entrustable Professional Activities (EPA), which translates generic competencies into observable and evaluable clinical tasks, such as obtaining a complete patient history. Successful implementation requires supporting infrastructure, including e-portfolio and learning management systems (LMS) for longitudinal tracking. The crucial challenge lies in transforming the teacher from a \"clinical expert\" to a \"clinical-pedagogical expert\", which necessitates restructuring the academic career with incentives, promotions, and compensation that value pedagogical training equally with clinical practice. Overcoming the institutional, faculty, and economic resistances generated by this reform depends on leadership capacity to manage change through the empowerment of leaders and modular micro-training.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7053"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13610913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinical determinants of levothyroxine dosage adjusted for various body weights].","authors":"Ricardo García-Cabello, Michelle Alejandra Melacio-Rodríguez","doi":"10.5281/zenodo.21462629","DOIUrl":"10.5281/zenodo.21462629","url":null,"abstract":"<p><strong>Background: </strong>Hypothyroidism requires treatment with levothyroxine to achieve a euthyroid state. Dosage based solely on body weight has limitations, particularly in patients with overweight or obesity.</p><p><strong>Objective: </strong>To evaluate whether the levothyroxine dose required to achieve a euthyroid state, adjusted for different body weight measures, varies according to sex, age, body mass index (BMI), and type of hypothyroidism.</p><p><strong>Material and methods: </strong>An analytical cross-sectional study was conducted in euthyroid adults with hypothyroidism receiving levothyroxine therapy between August 2024 and August 2025. Patients with recent dose adjustments or conditions affecting drug absorption were excluded. Absolute doses and doses adjusted for actual body weight, ideal body weight, adjusted body weight, and fat-free mass were analyzed.</p><p><strong>Results: </strong>A total of 101 patients were included; 76.2% were women and 23.8% men, with a mean age of 50.8 ± 14.9 years. Women received higher levothyroxine doses adjusted for ideal body weight and fat free mass than men. Overweight and obese patients received higher total doses and higher ideal weight adjusted doses than patients with normal BMI. No differences were observed in levothyroxine dose adjusted for any body weight for age or type of hypothyroidism.</p><p><strong>Conclusions: </strong>Sex influences levothyroxine doses adjusted for ideal body weight and fat free mass, while BMI status influences total and ideal weight adjusted doses.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7090"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13610908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduardo Daniel Anica-Malagón, Jesús Ignacio Hernández-Alcázar
{"title":"[Pharmacological management of pain in chronic wounds and stomas in adult patients].","authors":"Eduardo Daniel Anica-Malagón, Jesús Ignacio Hernández-Alcázar","doi":"10.5281/zenodo.21462810","DOIUrl":"10.5281/zenodo.21462810","url":null,"abstract":"<p><p>Pain associated with chronic wounds and stomas is a frequent and complex clinical problem that is often underestimated and undertreated. Its pathophysiology is multifactorial, since it combines nociceptive, inflammatory, and neuropathic mechanisms, which justifies the need for a comprehensive, multimodal pharmacological approach. This review critically analyzes recent evidence on systemic, topical, and adjuvant treatments used for the management of baseline pain, procedure-related pain, neuropathic pain, and breakthrough pain in patients with chronic wounds or stomas. Systematic reviews, clinical trials, and clinical practice guidelines published over the past 5 years were included. Non-opioid analgesics and opioids remain as the cornerstone of pharmacological treatment; however, their effectiveness may be limited when neuropathic components are unrecognized or poorly characterized. Topical formulations of local anesthetics, opioids, and emerging agents have demonstrated benefits, particularly in pain associated with wound care and local procedures. Likewise, gabapentinoids and dual-action antidepressants are effective in the management of neuropathic pain, while rapid-onset opioids may be considered for breakthrough pain in selected clinical contexts. Although the available evidence is heterogeneous, it supports an individualized approach that integrates different mechanisms of action and considers wound or stoma characteristics, patient comorbidities, and clinical safety aspects.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7115"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13610887/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Enrique Pulido-Contreras, Brenda Patricia Gramer-Muñoz, Miguel Ángel García-Padilla, Carlos Rios-Melgarejo
{"title":"[Democratization of the anatomical endoscopic enucleation of the prostate with bipolar energy].","authors":"Enrique Pulido-Contreras, Brenda Patricia Gramer-Muñoz, Miguel Ángel García-Padilla, Carlos Rios-Melgarejo","doi":"10.5281/zenodo.21462802","DOIUrl":"10.5281/zenodo.21462802","url":null,"abstract":"<p><p>Bipolar enucleation of the prostate (BipolEP) has emerged as an effective, safe, and cost-efficient surgical option for managing benign prostatic hyperplasia (BPH), particularly in large glands. The objective of this study was to analyze recent evidence on BipolEP and comparing it with other endoscopic enucleation techniques using holmium and thulium lasers. It was carried out a review through a search of articles published in PubMed between 2020 and 2025, and 35 relevant studies were included. Evidence analyzed demonstrate that BipolEP achieves complete adenoma removal, improves Qmax and IPSS, and reduces postvoid residual volume, with complication rates comparable to those of laser-based technologies. Its superior hemostatic profile lowers equipment costs that enable complete enucleation and adenoma resection with the mushroom technique without the need for a morcelator, while at the same time it eases a shorter learning curve, because urologists are accustomed to the bipolar resectocope and they support its implementation in resource-limited settings. However, although available data confirm its efficacy and reproducibility, it remains the need for multicenter studies with long-term follow-up to consolidate its durability and standardization.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7116"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13610905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Alberto Godínez-Chaparro, Armando Cortes-Hernández
{"title":"Mycosis fungoides in a Mexican pediatric series: Clinical, immunophenotypic, and therapeutic features.","authors":"Juan Alberto Godínez-Chaparro, Armando Cortes-Hernández","doi":"10.5281/zenodo.21462693","DOIUrl":"10.5281/zenodo.21462693","url":null,"abstract":"<p><strong>Background: </strong>Mycosis fungoides (MF) is a primary cutaneous lymphoma that in pediatric patients is frequently misdiagnosed as a benign dermatosis. Studies in Mexican children are limited.</p><p><strong>Objective: </strong>To describe the clinical, immunophenotypic, and therapeutic characteristics of MF in a Mexican pediatric series.</p><p><strong>Material and methods: </strong>It was conducted a cross-sectional study between 2017-2025 at a hospital in Mexico City, which included 17 pediatric patients younger than 18 years of both sexes with a diagnosis of MF.</p><p><strong>Results: </strong>They were 13 males and 4 females, with a mean age at diagnosis of 11.9 ± 2.8 years and a median disease duration of 3 years; 52.9% of patients were referred with a diagnosis of atopic dermatitis. The most frequent clinical variant was hypopigmented (64.7%). All cases were classified as stage IB. Diagnosis required a median of 2 biopsies, with delays of up to 12 months (range 3-24). All cases showed epidermotropism with CD3 and CD4 positivity (100%), and 88.2% showed CD8 positivity. All patients received topical corticosteroids; 3 received phototherapy, 3 methotrexate, and 3 photopheresis. The classic form of MF was associated with the presence of erythematous patches and erythematous scaly plaques, as well as, in some cases, with the use of methotrexate and phototherapy.</p><p><strong>Conclusions: </strong>Pediatric MF poses a diagnostic challenge due to its clinical similarity to common dermatoses. Although prognosis is generally favorable, its recurrence requires prolonged follow-up.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7110"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13610903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emmanuel Peña Gomez-Portugal, Cristian De Jesús García-Aguilar, Andrea Alondra Hernández-Gurrola
{"title":"[Thoracoscopic diaphragmatic plication technique in a patient with refractory hepatic hydrothorax].","authors":"Emmanuel Peña Gomez-Portugal, Cristian De Jesús García-Aguilar, Andrea Alondra Hernández-Gurrola","doi":"10.5281/zenodo.21462896","DOIUrl":"10.5281/zenodo.21462896","url":null,"abstract":"<p><strong>Background: </strong>Refractory hepatic hydrothorax (HH) is the persistent accumulation of pleural effusion secondary to portal hypertension, in the absence of cardiopulmonary or pleural etiology. It is diagnosed in patients with cirrhosis and it is a diagnosis of exclusion. Initial management consists of diuretics and sodium restriction, with a success rate of 75-80%; the remainder progress to refractory HH. Diaphragmatic plication via thoracoscopy combined with chemical pleurodesis has emerged as a therapeutic alternative to improve quality of life and reduce hospitalizations.</p><p><strong>Case report: </strong>A 64-year-old woman with cirrhosis due to primary biliary cholangitis, Child-Pugh B (9 points), MELD 3.0: 15 points (bilirubin 1.7 mg/dL, INR 1.0, creatinine 1.3 mg/dL, sodium 140 mEq/L, albumin 2.0 g/dL). The patient presented with pleuritic pain, dyspnea mMRC IV, and transudative pleural effusion. Diuretic therapy with propranolol, furosemide, and spironolactone was administered, along with sodium restriction (80-90 mEq/day) and fluid restriction (< 2 L/day), without improvement and with symptom progression. A diagnosis of refractory HH was made, and thoracoscopic diaphragmatic plication with chemical pleurodesis was performed, resulting in a reduction of the effusion and clinical improvement. 6 months later, there was no clinical or radiological recurrence.</p><p><strong>Conclusions: </strong>Diaphragmatic plication closes defects that communicate between the abdominal and pleural cavities, reducing the pleuroperitoneal gradient. Chemical pleurodesis induces pleural adhesion and obliteration of the space. The combination of both techniques increases therapeutic effectiveness.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e7011"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13600736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dalia Kelly Hernández-Peláez, Carlos Francisco De la Mora-López, Martín Vega-Dovalí
{"title":"[Case report of human myiasis caused by Cochliomyia hominivorax in Mexico].","authors":"Dalia Kelly Hernández-Peláez, Carlos Francisco De la Mora-López, Martín Vega-Dovalí","doi":"10.5281/zenodo.21462901","DOIUrl":"10.5281/zenodo.21462901","url":null,"abstract":"<p><strong>Background: </strong>Myiasis is the infestation of living or necrotic tissues of humans and animals by dipteran larvae. It is endemic to tropical and subtropical regions of the Americas and Africa. It occurs most frequently in vulnerable populations, and it is associated with open wounds, poor hygiene, and predisposing medical conditions. The objective was to describe 2 clinical cases of cutaneous myiasis in humans confirmed in Mexico.</p><p><strong>Clinical cases: </strong>The first case occurred in a 77-year-old woman, and it was secondary to mild traumatic brain injury according to the World Health Organization (WHO) classification. The second in a 74-year-old man with advanced basal cell carcinoma on the right side of his face. In both cases, samples were sent to the State Public Health Laboratory (LESP) and the National Service for Agrifood Health, Safety and Quality (SENASICA), where the taxonomic diagnosis of Cochliomyia hominivorax was confirmed.</p><p><strong>Conclusions: </strong>Myiasis is a preventable disease of epidemiological importance which was considered eradicated in Mexico since 1991. Early diagnosis and comprehensive medical-surgical treatment allow for a favorable evolution and prognosis, with the prevention of serious complications.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"64 5","pages":"e6879"},"PeriodicalIF":0.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13600737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}