{"title":"[Comment on the article \"Erythrocyte morphological alterations as predictors of kidney injury severity\"].","authors":"José Alfredo Feria-Ramírez","doi":"10.5281/zenodo.15178497","DOIUrl":"https://doi.org/10.5281/zenodo.15178497","url":null,"abstract":"<p><p>After reviewing the article \"Erythrocyte morphological alterations as predictors of kidney injury severity\" published by Cruz-Balbuena et al., we can emphasize that erythrocytic changes have several pathophysiological mechanisms, such as iron deficiency, vitamin B12 deficiency, and the pro-inflammatory state of chronic kidney disease (CKD) itself. Furthermore, due to the accumulation of uremic toxins that result in a shortened lifespan of erythrocytes, a selection bias was found in their population and a positive but non-linear correlation. There are already several well-established progression markers with better correlation.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6505"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Alejandro Cabrera-Gaytán, Concepción Grajales-Muñiz, Teresita Rojas-Mendoza, Lumumba Arriaga-Nieto, Alfonso Vallejos-Parás
{"title":"[Epidemiological surveillance at IMSS: a review of institutional successes].","authors":"David Alejandro Cabrera-Gaytán, Concepción Grajales-Muñiz, Teresita Rojas-Mendoza, Lumumba Arriaga-Nieto, Alfonso Vallejos-Parás","doi":"10.5281/zenodo.15178531","DOIUrl":"https://doi.org/10.5281/zenodo.15178531","url":null,"abstract":"<p><p>The Mexican Institute for Social Security (IMSS) has recently celebrated 8 decades of existence; its contribution to the processes of medical care, public health and epidemiological surveillance in Mexico have been among its cornerstones. This article presents some selected points of the history of the Institute's epidemiological surveillance, from its birth in the organic structure to the successes of identifying agents and responding to outbreaks, epidemics and pandemics that have been milestones in the modern history of our country, such as diseases preventable by vaccination, pathologies affecting the respiratory tract, as well as the gastrointestinal tract, vector-borne and sexually transmitted diseases that have been subject to sectoral epidemiological surveillance, not only in terms of epidemiological surveillance, but also as contributions of research. Finally, it is a brief recapitulation to know and understand the events that the Institute have experienced, i. e., where we come from, what has been achieved in order to understand where we are and what can be built and done in the future.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6551"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Genaro Efraín Hernández-Alatriste, Fernando Torres-Zapiain, Martha Alicia Hernández-González
{"title":"[Effectiveness of the middle turbinate flap for the treatment of spontaneous fistulas].","authors":"Genaro Efraín Hernández-Alatriste, Fernando Torres-Zapiain, Martha Alicia Hernández-González","doi":"10.5281/zenodo.15178461","DOIUrl":"https://doi.org/10.5281/zenodo.15178461","url":null,"abstract":"<p><strong>Background: </strong>Currently there is no certainty on which is the best treatment for spontaneous cerebrospinal fluid (CSF) fistulas. This study aimed to test the effectiveness of the pedicled middle turbinate flap (PMTF) in the treatment of said fistulas, located in the anterior skull base floor (ASBF).</p><p><strong>Objective: </strong>To demonstrate the reduction in recurrence of spontaneous CSF fistulas in the ASBF treated with endoscopic endonasal PMTF.</p><p><strong>Material and methods: </strong>Ambispective cohort study which included patients with spontaneous CSF fistulas located in the ASBF, treated with PMTF and nasoseptal flap (NSF) by endoscopic endonasal route in a third-level hospital from March 1, 2020, to February 28, 2023. 2 groups were compared: group A, for patients treated with PMTF, and group B, patients treated with NSF. It was calculated chi squared for recurrence, complications and surgical reintervention. A p value < 0.05 was considered significant.</p><p><strong>Results: </strong>The total was of 13 patients. The most frequent cause was spontaneous (9 cases). PMTF was used in 7 cases and NSF in 6. In group A the recurrence was 42%, and in group B 66% (p = 0.38). Only 1 patient in group A underwent reoperation vs. 4 in group B (p = 0.05).</p><p><strong>Conclusions: </strong>The use of PMTF has fewer cases of recurrence compared to NSF, even though it was not statistically significant. The statistical significance for reintervention in group A suggests that PMTF may be a viable option for these patients.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6574"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Comment on the article \"Retinal ischemia as an early marker of renal failure in non-proliferative retinopathy\"].","authors":"Dulce Paola Grajales-Garcia","doi":"10.5281/zenodo.15178487","DOIUrl":"https://doi.org/10.5281/zenodo.15178487","url":null,"abstract":"<p><p>Regarding the article \"Retinal ischemia as an early marker of renal failure in non-proliferative retinopathy\" by Muñoz-Cornejo et al., retinal ischemia reflects microvascular damage, hyperglycemia causes endothelial damage, vascular occlusion, and the release of proangiogenic factors, which is linked with the presence of retinopathy and nephropathy. However, the study has limitations: it uses outdated terminology, it does not evaluate key renal markers, and it does not control for confounding factors. Although 25 (45%) of the patients with retinal ischemia had albuminuria, no correlation with renal deterioration was proven, and renal damage could precede ocular damage. More precise parameters are needed to establish this association.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6151"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Reflection and opportunity: Circular economy and health in Mexican public sector].","authors":"Carla Martínez Castuera-Gómez","doi":"10.5281/zenodo.15178438","DOIUrl":"https://doi.org/10.5281/zenodo.15178438","url":null,"abstract":"<p><p>The paradigm of complexity establishes links between health and economy which enable opportunities to reflect on current theoretical trends and practical cases, existing in the Mexican public sector. With the aim of contributing to such reflection, this document makes a theoretical review of the term circular economy, mentions some examples published in international literature, and points out similar Mexican cases under development, which have not been proposed from a health and economics transdisciplinary vision. In the context of this scientific journal, targeted for health professionals, it is deemed relevant to induce new conversations that encourage establishing links with other sectors to enrich medical practice and scientific research.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6654"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144033308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Comment on the article \"Elevated neutrophil-lymphocyte ratio and delayed graft function\"].","authors":"Yessica López-Cabrera","doi":"10.5281/zenodo.15178491","DOIUrl":"https://doi.org/10.5281/zenodo.15178491","url":null,"abstract":"<p><p>Kidney transplantation is the replacement therapy of choice in patients with end-stage chronic kidney disease; however, complications such as delayed graft function increase the risk of rejection and reduce survival. It has been made a search of biomarkers as accessible, and reproducible low-cost tools that allow to predict risk. Among them, it has been evaluated the neutrophil-lymphocyte index, an inflammatory biomarker associated with ischemia-reperfusion lesion present in these patients. It was made a review to evaluate its predictive usefulness in post-transplant evaluation and follow-up.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6268"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ricardo Leal-León, Antonio Tirado-Motel, Marian Escribano-Ponce, Vanessa González-Ruiz, María Teresa de Jesús Vega-González
{"title":"[Flagellate erythema secondary to bleomycin: case report with favorable outcome].","authors":"Ricardo Leal-León, Antonio Tirado-Motel, Marian Escribano-Ponce, Vanessa González-Ruiz, María Teresa de Jesús Vega-González","doi":"10.5281/zenodo.15178515","DOIUrl":"https://doi.org/10.5281/zenodo.15178515","url":null,"abstract":"<p><strong>Background: </strong>Flagellate erythema (FE) is a multifactorial dermatosis, frecuently related to the the use of certain drugs. It can occur in up to 20% of patients treated with bleomycin. Drug accumulation in the skin can be due to the lack of the enzyme bleomycin hydrolase. It presents as a widespread dermatosis, predominantly affecting the trunk and upper extremities, characterized by erythematous-hyperpigmented macules of variable size, with a linear arrangement and a \"whip-like\" appearance, associated with intense pruritus. Management focuses on relieving pruritus with antihistamines and topical steroids, although discontinuation of bleomycin is essential for complete resolution.</p><p><strong>Case report: </strong>A 19-year-old woman with a history of stage IIIB left ovarian dysgerminoma was undergoing combined chemotherapy (bleomycin, etoposide, and cisplatin). After 3 months of treatment, she developed a widespread dermatosis on the neck and posterior thoracic region, consisting of dark brown hyperpigmented spots with a linear configuration and variable sizes, associated with pruritus, without other symptoms. FE due to bleomycin was diagnosed. High-potency topical corticosteroids were prescribed. After discontinuing bleomycin, there was a progressive disappearance of the dermatosis until complete resolution.</p><p><strong>Conclusion: </strong>The bleomycin-induced FE must be identified early for appropriate management that allows the continuation of antineoplastic treatment. Discontinuation of the drug should be considered when the patient's quality of life is compromised and balanced with oncological control, which optimizes antineoplastic therapy.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6585"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lumumba Arriaga-Nieto, Alfonso Vallejos-Parás, David Alejandro Cabrera-Gaytán, Concepción Grajales-Muñiz, Yadira Pérez-Andrade
{"title":"[Brief organizational history of epidemiological surveillance at the IMSS].","authors":"Lumumba Arriaga-Nieto, Alfonso Vallejos-Parás, David Alejandro Cabrera-Gaytán, Concepción Grajales-Muñiz, Yadira Pérez-Andrade","doi":"10.5281/zenodo.15178520","DOIUrl":"https://doi.org/10.5281/zenodo.15178520","url":null,"abstract":"<p><p>The Mexican Institute for Social Security (IMSS) has been an institution that has been forged over 80 years of existence, with contributions to the history of public health and epidemiological surveillance in Mexico; to do so, over the course of its institutional life, it has had to adapt to the contexts, realities, challenges and unforeseen events in terms of medical, sanitary and epidemiological care. In this sense, the Institute has modified its organizational structure on several occasions at managerial level, and, consequently, within the federal entities and in the medical care units. For this reason, this manuscript summarizes the main milestones and events that the Institute has experienced, focusing on its organic structure related to epidemiological surveillance; for example, the birth of the Epidemiological Surveillance and Contingency Support Coordination, as well as the Network of Laboratories for Epidemiological Surveillance and its growth, following a review mainly of the organization manuals of the Medical Benefits Administration and various institutional reports that are published annually, with many successes that have resulted from these changes and the alliances within the Institute, as well as the external ones that recall the strength and flexibility of the Institute's organizational structure.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6418"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Atypical clinical and mortality in older adults hospitalized with COVID-19 pneumonia].","authors":"Tlalnelli Valencia-Blancas, Lucía Herlinda Pérez-Orozco, Verónica Durán-Góme, Evelín García-Barboza, Roberto Rivelino López-Anguiano","doi":"10.5281/zenodo.15178449","DOIUrl":"10.5281/zenodo.15178449","url":null,"abstract":"<p><strong>Background: </strong>Pneumonia caused by SARS-CoV-2 is a public health problem. Older adults are vulnerable and the atypical presentation delays diagnosis and increases mortality. In this group the atypical clinical manifestations are more frequent.</p><p><strong>Objective: </strong>To identify the clinical manifestations and mortality of COVID-19 pneumonia in hospitalized older adults.</p><p><strong>Material and methods: </strong>A comparative cross-sectional observational study was carried out, from July 1, 2020, to December 31, 2021, in a general hospital of Mexico City. Patients aged 60 years or more who were hospitalized with a diagnosis of COVID-19 were included.</p><p><strong>Results: </strong>267 older adults participated; 53.9% were men, with a median age of 74 years. The most frequent comorbidities in this population were type 2 diabetes mellitus (T2DM), hypertension and chronic obstructive pulmonary disease (COPD). 41.2% showed atypical presentation of the disease; mortality in the studied population was 53.5%.</p><p><strong>Conclusions: </strong>The atypical presentation of COVID-19 pneumonia is common in adults over 60 years of age and it increases significantly as they become older. The absence of typical symptoms of pneumonia and the ignorance of the most common signs could delay diagnosis and timely care in this age group, which may increase complications and mortality.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6350"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alma Patricia González, Diana Gabriela Camacho-Osuna, Raymundo López-Martínez, Yaira María José Rocha-Sánchez, Carlos Paque-Bautista, José Luis Felipe Luna-Anguiano, José de Jesús Valderrama-Santillán, Gloria Patricia Sosa-Bustamante
{"title":"[Negative affectivity in new mothers during the COVID-19 lockdown].","authors":"Alma Patricia González, Diana Gabriela Camacho-Osuna, Raymundo López-Martínez, Yaira María José Rocha-Sánchez, Carlos Paque-Bautista, José Luis Felipe Luna-Anguiano, José de Jesús Valderrama-Santillán, Gloria Patricia Sosa-Bustamante","doi":"10.5281/zenodo.15178479","DOIUrl":"https://doi.org/10.5281/zenodo.15178479","url":null,"abstract":"<p><strong>Background: </strong>Confinement due to health emergencies such as the coronavirus disease 19 (COVID-19) creates additional challenges for pregnant women (PW), negatively influencing their mental health.</p><p><strong>Objective: </strong>To evaluate the presence of symptoms suggestive of depression (SSD), anxiety (SSA), and stress (SSS) and associated factors in PW during confinement due to the COVID-19 pandemic.</p><p><strong>Material and methods: </strong>Analytical and prolific prevalence study carried out in hospitalized primigravidae PW, aged 14 to 41 years. Clinical, psychosocial, and sociodemographic data from the PM and medical records were collected, and the DASS-21 questionnaire was administered. Chi-square or Fisher's exact test, odds ratio (OR), and logistic regression were used.</p><p><strong>Results: </strong>232 PW with a median age of 23 years (20-27) were included. The incidence of SSD was 37.07%, SSA 45.69%, SSS 35.78%. Risk factors for SSD were not having a partner: OR 2.12 (95% CI 1.15-3.93), p = 0.01, and having low socioeconomic status 3.06 (95% CI 1.70-5.49), p = 0.0001. In SSA, unemployment was 1.76 (1.04-2.96), p = 0.03. And for SES, basic education showed 0.49 (95% CI 0.28-0.88), p = 0.01, low socioeconomic status 1.80 (95% CI 1.01-3.22), p = 0.04, and comorbidities 2.15 (95% CI 1.04-4.44), p = 0.03.</p><p><strong>Conclusion: </strong>During the COVID-19 lockdown, the frequency of SSD, SSA and SSS in primigravidae PW was high, and associated factors were not having a partner, low socioeconomic status, unemployment, and comorbidities.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 3","pages":"e6658"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}