Revista medica del Instituto Mexicano del Seguro Social最新文献_第7页

[Association of T CD3+/T CD8+ lymphocytes in lymphatic and perineural infiltration in colorectal cancer]. [T CD3+/T CD8+淋巴细胞与结直肠癌淋巴和神经周围浸润的关系]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-01-03 DOI: 10.5281/zenodo.14200044

Edgar Joaquín Cortés-Torres, María Del Refugio Flores-Betancourt, Alejandro González-Ojeda, Clotilde Fuentes-Orozco, Gabino Cervantes-Guevara, Enrique Cervantes-Pérez, Alejandro Ramírez-Velázquez, Ana Karen Hernández-Guzmán

{"title":"[Association of T CD3+/T CD8+ lymphocytes in lymphatic and perineural infiltration in colorectal cancer].","authors":"Edgar Joaquín Cortés-Torres, María Del Refugio Flores-Betancourt, Alejandro González-Ojeda, Clotilde Fuentes-Orozco, Gabino Cervantes-Guevara, Enrique Cervantes-Pérez, Alejandro Ramírez-Velázquez, Ana Karen Hernández-Guzmán","doi":"10.5281/zenodo.14200044","DOIUrl":"https://doi.org/10.5281/zenodo.14200044","url":null,"abstract":"Background: Colorectal cancer (CRC) is one of the most common and lethal neoplasia in the world. Key prognostic factors include lymphovascular and perineural infiltration, which negatively affect the disease by increasing the risk of metastasis. Studies indicate that low levels of CD8+ and CD3+ T cells may be associated with early metastasis.Objective: To evaluate the sensitivity and specificity of preoperative serum cytotoxic T lymphocytes (CD8+ and CD3+) with lymphatic and perineural infiltration in colorectal cancer.Material and methods: Prospective, cross-sectional, analytical study on cytotoxic T lymphocytes (CD8+ and CD3+). Descriptive statistics, measures of central tendency and dispersion for quantitative variables, frequency and percentage for qualitative variables were used. The samples obtained were associated with the presence of lymphovascular or perineural infiltration.Results: 37 patients were included, with a mean age of 58 ± 10.9 years; 24 (64.8%) were female. 16 (43.2%) were diagnosed with malignant colon neoplasms, and 21 (56.7%) with malignant rectal tumors. Lymphovascular infiltration was found in 13 (35.1%) and 18 (48.6%) perineural infiltrates. CD8+ T lymphocyte levels were 219 cells/AL ± 140.5 cells/AL, and 16 (43.2%) had low levels. CD3+ T lymphocytes averaged with 943 cells/uL ± 640.4 cells/AL, and 16 (43.2%) had low levels.Conclusions: Histopathologically we found an association between the serum level of CD3+ and CD8+ T cells and lymphovascular and perineural infiltration. Additional research has to be done to strengthen the results obtained.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e6321"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Sick leaves in military residents and COVID-19 in Mexico]. [军队居民的病假和墨西哥的COVID-19]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-01-03 DOI: 10.5281/zenodo.14200952

Dulce Carolina Hernández-Mendoza, Angélica Castro-Ríos

{"title":"[Sick leaves in military residents and COVID-19 in Mexico].","authors":"Dulce Carolina Hernández-Mendoza, Angélica Castro-Ríos","doi":"10.5281/zenodo.14200952","DOIUrl":"10.5281/zenodo.14200952","url":null,"abstract":"Background: The training of health personnel is a priority on global, regional and national agendas. Sick leave is the mechanism that protects people from carrying out activities that may aggravate their health status. In Mexico, there is little information about sick leaves in resident doctors, military doctors in training and even more about the effect of the pandemic on this.Objective: To compare the incidence of sick leaves in resident doctors of the Military Graduate School of Health in the face of the appearance of COVID-19.Material and methods: The study population was medical personnel in training which was active in the 2020 cycle. The design was observational and longitudinal of the sick leaves that occurred before the pandemic (cycle 2019) and during the pandemic (cycles 2020 and 2021). Incidence rates were estimated and compared.Results: 204 residents were included, out of which 49.5% presented at least one sick leave. The incidences due to Other causes were 3.2, 4.4 and 8.3 cases per school year 2019-2021, respectively, while due to COVID-19 it was 33.3% (2020) and 6.9% (2021). The incidence ratio between pandemic (2020)/pre-pandemic (2019) periods was 12.4 and it was statistically significant. The incidence of COVID-19 increased by year of residence, with an incidence ratio (advanced years/initial years) of 1.5.Conclusions: The incidence of sick leaves increased significantly due to the COVID-19 pandemic. The incidence rate of sick leaves due to COVID-19 was increasing per year of residence.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e6569"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Intestinal perforation secondary to intestinal malrotation in an adult: Case report]. [成人继发于肠道旋转不良的肠穿孔1例报告]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-01-03 DOI: 10.5281/zenodo.14201190

Nora Lis Flores-Olmos, Francisco Javier Hernández-Álvarez, Ricardo Frausto-Luján, Montserrat Del Carmen Valencia-Romero

{"title":"[Intestinal perforation secondary to intestinal malrotation in an adult: Case report].","authors":"Nora Lis Flores-Olmos, Francisco Javier Hernández-Álvarez, Ricardo Frausto-Luján, Montserrat Del Carmen Valencia-Romero","doi":"10.5281/zenodo.14201190","DOIUrl":"10.5281/zenodo.14201190","url":null,"abstract":"Background: Intestinal malrotation is a congenital anomaly resulting from abnormal rotation of the intestine during fetal development, affecting its fixation and orientation. Although it is primarily diagnosed in infancy, it can cause severe complications in adults, such as intestinal obstruction, volvulus, and perforation. The objective is to illustrate the clinical presentation and management of intestinal malrotation in adults, highlighting the complications and the importance of early diagnosis.Clinical case: 53-year-old man with generalized abdominal distension and pain, nausea, vomiting, and absence of bowel movements. Computed tomography (CT) revealed free air and fluid in the abdominal cavity, suggesting intestinal perforation. Surgery revealed cecal perforation, necrosis of the ascending colon, and a characteristic malrotation pattern. A right hemicolectomy, resection of affected intestinal segments, and creation of a terminal ileostomy were performed.Conclusions: Intestinal malrotation in adults can present with nonspecific symptoms, complicating its diagnosis. Secondary obstruction can lead to increased intraluminal pressure, ischemia, and perforation. Perforation, resulting from prolonged obstruction, requires early diagnosis with CT. Urgent surgical intervention is essential to repair the perforation and the intestinal malrotation. The Ladd procedure is the standard treatment to correct malrotation and prevent future complications.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e6394"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Doege-Potter syndrome and intra-abdominal giant solitary fibrous tumor: Case report]. [doge - potter综合征合并腹腔内巨大孤立性纤维性肿瘤1例]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-01-03 DOI: 10.5281/zenodo.14201059

Antonio Lira-Díaz, Daniel Arizpe-Vilana, María Guadalupe Jazmín de Anda-González

{"title":"[Doege-Potter syndrome and intra-abdominal giant solitary fibrous tumor: Case report].","authors":"Antonio Lira-Díaz, Daniel Arizpe-Vilana, María Guadalupe Jazmín de Anda-González","doi":"10.5281/zenodo.14201059","DOIUrl":"10.5281/zenodo.14201059","url":null,"abstract":"Background: Doege-Potter syndrome has been reported in solitary fibrous tumors and it is characterized by severe, sustained, and refractory hypoglycemia associated with non-pancreatic tumors, particularly solitary fibrous tumor of the pleura. An uncommon case of solitary fibrous tumor associated with severe hypoglycemia and abdominal location is reported.Clinical case: A 63-year-old woman presented with difficult-to-control hypoglycemia, intestinal obstruction, and subsequent sepsis. Imaging studies showed an abdominal-predominant neoplasm infiltrating the spine. Histopathological examination of the biopsy and surgical specimen confirmed a solitary fibrous tumor. Once resected, the hypoglycemia diminished and Doege-Potter syndrome was diagnosed.Conclusion: This case stands out due to its presentation with severe refractory hypoglycemia, the location of the tumor in the abdomen, and vertebral invasion, given that most solitary fibrous tumors are found in the lungs and originate from the pleura. Uncommon causes of hypoglycemia in non-diabetic patients should be considered, such as Doege-Potter syndrome.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e6127"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Main clinical factors associated with hypoglycemia in patients with type 2 diabetes]. 【2型糖尿病患者低血糖相关的主要临床因素】。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-01-03 DOI: 10.5281/zenodo.14200033

Berenice Del Carmen Sánchez-González, Maricarmen Tapia-Venancio, Arturo García-Galicia, Ricardo Adolfo Parker-Bósquez, Minerva Salomé Pulido-Martínez, Diana López-García, Álvaro José Montiel Jarquín

{"title":"[Main clinical factors associated with hypoglycemia in patients with type 2 diabetes].","authors":"Berenice Del Carmen Sánchez-González, Maricarmen Tapia-Venancio, Arturo García-Galicia, Ricardo Adolfo Parker-Bósquez, Minerva Salomé Pulido-Martínez, Diana López-García, Álvaro José Montiel Jarquín","doi":"10.5281/zenodo.14200033","DOIUrl":"https://doi.org/10.5281/zenodo.14200033","url":null,"abstract":"Background: Hypoglycemia is a frequent acute complication of type 2 diabetes (T2D), and it is a medical emergency. The etiology is fundamental for timely diagnosis and treatment.Objective: To describe the most frequent clinical characteristics of patients with T2D with hypoglycemia, admitted to the Emergency Department of a second-level hospital.Material and methods: Descriptive and cross-sectional study, carried out in a second-level hospital in Puebla, Mexico, in adults with T2D who were admitted with glycemia < 70 mg/dL. Those with psychiatric diagnoses were excluded. Age, sex, schooling, duration of diabetes, comorbidities, capillary glycemia, treatment, symptomatology, drug addiction, and (their) caregivers were evaluated. Patients signed informed consent. Descriptive statistics, as well as Kolmogorov-Smirnov test were used. The degree of hypoglycemia was correlated with the different clinical characteristics with Spearman's Rho. A p ≤ 0.05 was considered significant.Results: 224 patients were recruited, with a mean age of 60 (standard deviation [SD] ±14) years. Male sex (116 patients, 51.7%), age 56 to 65 years (54, 24.1%), primary schooling (79, 35.3%), evolution of 10-20 years (80, 35.7%), comorbidity hypertension (91, 40.6%) moderate hypoglycemia (96, 42. 9%), oral hypoglycemic treatment (54, 39.7%), adrenergic symptoms (120, 53.6%), and tobacco addiction (64, 28.6%) were predominant.Conclusion: The population studied was characterized by having chronic management and control of diabetes mellitus based on oral hypoglycemic agents, being in the 5th decade of life and having basic scholarship.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e6346"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Vitamin D deficiency: positioning of the Medical Nutrition Research Unit]. 【维生素D缺乏症：医学营养研究单位的定位】。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-01-02 DOI: 10.5281/zenodo.14199893

Jorge Maldonado-Hernández, Nancy Anahí Pérez-Ramírez, María de Los Ángeles González-Atilano, Alva Belen Morales-Villar, María de Lourdes Barbosa-Cortés

{"title":"[Vitamin D deficiency: positioning of the Medical Nutrition Research Unit].","authors":"Jorge Maldonado-Hernández, Nancy Anahí Pérez-Ramírez, María de Los Ángeles González-Atilano, Alva Belen Morales-Villar, María de Lourdes Barbosa-Cortés","doi":"10.5281/zenodo.14199893","DOIUrl":"10.5281/zenodo.14199893","url":null,"abstract":"As part of the celebration of the 40th anniversary of the Medical Research Unit in Nutrition (UIMN), we have prepared this manuscript with the main objective to disseminate updated information of vitamin D topic. Given that vitamin D deficiency is a nutritional issue in Mexico and worldwide, we consider it relevant to establish a preventive stance that may be useful for health professionals and society in general. The Mexican Institute of Social Security (IMSS), as the most renowned institution for health care and social protection of Mexicans, reaffirms its commitment to communicate the findings made by its researchers and academics for the benefit of its members. In this document, we provide an updated review of the most significant topics addressed by the scientific community regarding the study of vitamin D, and we propose specific recommendations related to dietary intake, the issue of sun exposure with an emphasis on skin health, updated information on the use of sunscreen, and a section on vitamin D3 supplementation. Finally, we suggest some key recommendations that could help improve the nutritional status of this vitamin, which is utterly important at different stages of life and has numerous biological functions in the body.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 Suppl 1","pages":"e6507"},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12158444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Tribute to the Unidad de Investigación Médica en Nutrición]. [向营养医学研究单位致敬]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-01-02 DOI: 10.5281/zenodo.14199935

Maricela Rodríguez-Cruz

引用次数: 0

[Docosahexaenoic acid benefits on growth and body composition of septic neonates. Randomized trial]. 二十二碳六烯酸对脓毒症新生儿的生长和身体成分有益。随机试验]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-01-02 DOI: 10.5281/zenodo.14199811

Mariela Bernabe-García, Mardia López-Alarcón, Maricela Rodríguez-Cruz, María Dolores Rivera-Rodríguez, Raúl Villegas-Silva

{"title":"[Docosahexaenoic acid benefits on growth and body composition of septic neonates. Randomized trial].","authors":"Mariela Bernabe-García, Mardia López-Alarcón, Maricela Rodríguez-Cruz, María Dolores Rivera-Rodríguez, Raúl Villegas-Silva","doi":"10.5281/zenodo.14199811","DOIUrl":"10.5281/zenodo.14199811","url":null,"abstract":"Background: Neonatal sepsis is a global leading disease and causes retarded growth and undernourishment. The docosahexaenoic acid (DHA) has immunomodulatory effects, which may protect against the adverse effects of sepsis.Objective: To evaluate whether the enteral administration of DHA to neonates with late sepsis, reduces the negative impact on retarded growth and body reserves.Methods: Randomized double-blinded clinical trial in neonates who underwent surgery with diagnosis of late sepsis attended in the Neonatology Service. A group received 100 mg of DHA/day and the control group received olive oil, by enteral feeding for 14 days since the sepsis diagnosis. The change in anthropometry and body composition was evaluated from sepsis diagnosis to 14 days after. The changes were compared with Student´s T, one sample t and McNemar tests. The effect of the confounders was adjusted by general linear regression.Results: The DHA group compared with control group, had a greater length (1.7% ± 0.4 vs. 0.7% ± 0.2, p = 0.04), arm circumference (2.2% ± 1.2 vs. -3.7% ± 1.3, p = 0.001), bicipital skinfold (7.8% ± 6.1 vs. -11.8% ± 4.6, p = 0.02), and fat-free mass (4.5% ± 2.1 vs. -0.6% ± 2.0, p = 0.02), as well as a higher Z score of length/age (-0.0 ± 0.1 vs. -0.4 ± 0.1, p = 0.003) and head circumference/age (0.1 ± 0.2 vs. -0.4 ± 0.1, p = 0.002). The last ones remained significant after adjusting by confounders.Conclusions: Enteral DHA administration reduced the retarded growth and undernourishment in neonates with late sepsis.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 Suppl 1","pages":"e6356"},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Hypovitaminosis D and biochemical parameters of bone metabolism in children with leukemia]. [维生素D缺乏症与白血病患儿骨代谢生化指标的关系]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-01-02 DOI: 10.5281/zenodo.14199833

Lourdes Barbosa-Cortés, Salvador Atilano-Miguel, Víctor Manuel Cortés-Beltrán, Sharon Berenice Morales-Montes, Jorge Alfonso Martín-Trejo, Jorge Maldonado-Hernández, Juan Manuel Domínguez-Salgado

{"title":"[Hypovitaminosis D and biochemical parameters of bone metabolism in children with leukemia].","authors":"Lourdes Barbosa-Cortés, Salvador Atilano-Miguel, Víctor Manuel Cortés-Beltrán, Sharon Berenice Morales-Montes, Jorge Alfonso Martín-Trejo, Jorge Maldonado-Hernández, Juan Manuel Domínguez-Salgado","doi":"10.5281/zenodo.14199833","DOIUrl":"10.5281/zenodo.14199833","url":null,"abstract":"Introduction: 25(OH)D is key for maintaining bone health. Treatment of pediatric patients with acute lymphoblastic leukemia (ALL) has a negative effect on bone metabolism.Objective: To describe the frequency of hypovitaminosis D, changes in serum 25(OH)D concentrations, and the biochemical and hormonal markers of bone metabolism between diagnosis and referral in children with ALL.Material and methods: Prospective, longitudinal, cohort study in pediatric patients (4-17 years) with newly diagnosed B-cell ALL, and without treatment. Patients were summoned under fasting conditions, and a peripheral blood sample was taken to determine 25(OH)D, parathyroid hormone (PTH), phosphorus, and ionic calcium concentrations.Results: Of the 40 patients recruited, 7 were lost to follow-up, so only 33 were analyzed. 91% of the children had hypovitaminosis D. We observed a significant increase in ionic calcium concentrations from baseline levels (1.1 mmol/L vs. 1.2 mmol/L, p = 0.002). Analysis of the Δ of serum PTH and 25(OH)D concentrations showed an inverse relationship (rho = -0.397, p = 0.024).Conclusions: These findings confirm a high frequency of hypovitaminosis D. Low 25(OH)D levels may compromise calcium absorption and generate a compensatory increase in PTH.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 Suppl 1","pages":"e6482"},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Low intake and deficiency of vitamin D in Mexican adolescents with obesity]. [墨西哥肥胖青少年维生素D摄入量低和缺乏]。

Revista medica del Instituto Mexicano del Seguro Social Pub Date : 2025-01-02 DOI: 10.5281/zenodo.14199827

Alva Belen Morales-Villar, Jorge Maldonado-Hernández, Mildred Corina de la Concha-Duarte, Mardia Guadalupe López-Alarcón, María de Los Ángeles González-Atilano, María Elena Rodríguez-Palacios, Israel Domínguez-Calderón, Laura Rojas-Peña

{"title":"[Low intake and deficiency of vitamin D in Mexican adolescents with obesity].","authors":"Alva Belen Morales-Villar, Jorge Maldonado-Hernández, Mildred Corina de la Concha-Duarte, Mardia Guadalupe López-Alarcón, María de Los Ángeles González-Atilano, María Elena Rodríguez-Palacios, Israel Domínguez-Calderón, Laura Rojas-Peña","doi":"10.5281/zenodo.14199827","DOIUrl":"10.5281/zenodo.14199827","url":null,"abstract":"Background: Vitamin D (VD) deficiency and childhood obesity are a public health problem in Mexico. Both are related to the development of various chronic diseases. It is important to describe and identify the main risk factors involved in VD deficiency in this population.Objective: To describe VD intake in obese Mexican adolescents and evaluate its association with serum 25(OH)D concentrations.Material and methods: A cross-sectional study was performed in 80 obese adolescents from Mexico City. Sociodemographic, anthropometric, dietary intake, sun exposure, and physical activity data were collected. A blood sample was taken to determine serum 25(OH)D concentrations.Results: VD deficiency and insufficiency occurred in 30% and 42.2% of adolescents. The median VD intake was 110.4 IU/day and the mean sun exposure score was 13 ± 7.5. Serum 25(OH)D levels were correlated with vitamin D intake (p = 0.010). Concentrations of 25(OH)D in serum were similar when compared between sex, sunscreen use, season, and skin type (p > 0.05).Conclusions: VD deficiency in adolescents with obesity is high. In contrast with its dietary intake and degree of sun exposure which are considerably low. A significant association was observed between dietary VD intake and serum 25(OH)D concentrations.","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 Suppl 1","pages":"e6484"},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0