[Doege-Potter syndrome and intra-abdominal giant solitary fibrous tumor: Case report].

Abstract

Background: Doege-Potter syndrome has been reported in solitary fibrous tumors and it is characterized by severe, sustained, and refractory hypoglycemia associated with non-pancreatic tumors, particularly solitary fibrous tumor of the pleura. An uncommon case of solitary fibrous tumor associated with severe hypoglycemia and abdominal location is reported.

Clinical case: A 63-year-old woman presented with difficult-to-control hypoglycemia, intestinal obstruction, and subsequent sepsis. Imaging studies showed an abdominal-predominant neoplasm infiltrating the spine. Histopathological examination of the biopsy and surgical specimen confirmed a solitary fibrous tumor. Once resected, the hypoglycemia diminished and Doege-Potter syndrome was diagnosed.

Conclusion: This case stands out due to its presentation with severe refractory hypoglycemia, the location of the tumor in the abdomen, and vertebral invasion, given that most solitary fibrous tumors are found in the lungs and originate from the pleura. Uncommon causes of hypoglycemia in non-diabetic patients should be considered, such as Doege-Potter syndrome.