[Epidemiological and clinical aspects of Guilain-Barré syndrome, 2012-2022].

Background: Guillain-Barré syndrome (GBS) is an immune-mediated polyradiculoneuropathy, generally post-infectious, and is the leading cause of acute flaccid paralysis worldwide.

Objective: To describe the epidemiological, clinical and behavioral characteristics of Guillain-Barré syndrome.

Material and methods: An observational, cross-sectional and descriptive study was carried out. The records of all patients with GBS from 2012-2022 were reviewed, and information on epidemiological and clinical variables was obtained. The incidence was calculated for each of the study years and the trend for the study period using the Pearson correlation coefficient, considering p ≤ 0.05 statistically significant.

Results: A total of 477 cases were obtained, 67% were men, among the comorbidities, drug addictions were present in 31% of the cases. Most cases were preceded by a gastrointestinal infectious condition. The most common phenotype was acute motor axonal neuropathy. 29% showed up in summer. A statistically significant tendency to increase was observed (p ≤ 0.05) and a mortality of 2.5% with predominance in the axonal variety.

Conclusions: The results of this study cover a relatively long period compared to other reviews, the findings agree with previous studies. GBS showed a statistically significant tendency to increase.