[Surgical outcomes in patients with esophageal cancer in a third level center].

Edgar Joaquín Cortes-Torres, Miguel Angel Reyna-Silva, Alejandro González-Ojeda, Clotilde Fuentes-Orozco, Gabino Cervantes-Guevara, Ana Guadalupe Sánchez-Luna, Kathia Dayana Morfín-Meza, Andrea Garcia
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引用次数: 0

Abstract

Background: Esophageal cancer is the seventh most diagnosed neoplasm, with a higher prevalence in men. Tobacco and alcohol consumption, gastroesophageal reflux disease, and Barrett's esophagus are associated with the development of adenocarcinoma and squamous cell carcinoma.

Objective: To identify the clinical profile in patients with esophageal cancer at a tertiary care center.

Materials and methods: A cross-sectional, observational study. Patients with esophageal cancer were evaluated between January 2014 and July 2019. The study variables included sex, age, histological type, postoperative complications, mortality, and survival.

Results: A total of 34 patients were evaluated, with a mean age of 61.8 ± 8.9 years. 88.2% were men. Tumor location was as follows: lower third (76.5%), middle third (17.6%), and upper third (5.9%). The most common histological types were adenocarcinoma (67.6%) and squamous cell carcinoma (32.4%). Symptoms included: dysphagia in 34 (100%) and epigastric pain in 20 (58.8%). The types of surgeries performed were: transhiatal in 15 (44.1%), palliative in 15 (44.1%), Ivor Lewis in 1 (2.9%), and McKeown in 1 (2.9%). Postoperative complications included: respiratory (29.4%), anastomotic leak (20.6%), sepsis (11.8%), and fistula (2.9%). Mortality was 13 (38.2%) patients, and survival at 22 months was 22%.

Conclusions: Our study showed a higher prevalence of esophageal cancer in men over 60 years old with adenocarcinoma localized in the lower third of the esophagus. Despite chemotherapy treatment, patient survival remains poor due to late diagnosis in advanced stages of the disease, which limits tumor resectability and operability, leading to increased mortality.

[三级中心食管癌手术疗效分析]。
背景:食管癌是第七大确诊肿瘤,男性发病率较高。烟酒消费、胃食管反流病和巴雷特食管与腺癌和鳞状细胞癌的发生有关。目的:了解三级保健中心食管癌患者的临床特点。材料和方法:横断面观察性研究。2014年1月至2019年7月对食管癌患者进行评估。研究变量包括性别、年龄、组织学类型、术后并发症、死亡率和生存率。结果:共纳入34例患者,平均年龄61.8±8.9岁。88.2%为男性。肿瘤位置:下三分之一(76.5%),中三分之一(17.6%),上三分之一(5.9%)。最常见的组织学类型是腺癌(67.6%)和鳞状细胞癌(32.4%)。症状包括:34例(100%)吞咽困难,20例(58.8%)胃脘痛。手术类型为:经口15例(44.1%),姑息15例(44.1%),Ivor Lewis 1例(2.9%),McKeown 1例(2.9%)。术后并发症包括:呼吸(29.4%)、吻合口漏(20.6%)、败血症(11.8%)、瘘(2.9%)。死亡率为13例(38.2%),22个月生存率为22%。结论:我们的研究显示,60岁以上的男性中,腺癌位于食管下三分之一的食管癌患病率较高。尽管进行了化疗,但由于晚期诊断较晚,患者的生存率仍然很低,这限制了肿瘤的可切除性和可操作性,导致死亡率增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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