Revista medica del Instituto Mexicano del Seguro Social最新文献

{"title":"[Seroprevalence of infectious agents in blood donors and their components].","authors":"Berenice Mejía-Aguirre, Ana Karen Luna-Vargas, Gamaliel Benítez-Arvizu","doi":"10.5281/zenodo.14616969","DOIUrl":"https://doi.org/10.5281/zenodo.14616969","url":null,"abstract":"<p><strong>Background: </strong>The seroprevalence of infectious agents in donors of blood and blood components is a relevant factor related to the biosecurity of blood components, therefore, the adequate choice of laboratory methods for screening, confirmatory and/or supplementary tests with high sensitivity and specificity.</p><p><strong>Objective: </strong>To estimate the seroprevalence of infectious agents transmitted by blood transfusion in blood donors during the period 2020 to 2023 at the CMN Siglo XXI Blood Bank.</p><p><strong>Material and methods: </strong>Descriptive, observational, retrospective study in 180,120 eligible blood donors and their components from the CMN Siglo XXI Blood Bank, between 18 and 65 years of age with reactive serology, during the period 2020-2023. The reactive serological markers of donors registered in the TESI-HEXABANK system and confirmatory/supplementary tests were analyzed. For the univariate analysis, Excel and SPSS version 26 were used.</p><p><strong>Results: </strong>The present study estimated that the seroprevalence of infectious agents transmitted by transfusion from 2020 to 2023 was 1.38% (n = 2489). The most seroprevalent marker was Treponema pallidum at 0.64%, followed by hepatitis C virus at 0.27%, human immunodeficiency virus at 0.19%, Trypanosoma cruzi at 0.15% and hepatitis B virus at 0.09%.</p><p><strong>Conclusions: </strong>The seroprevalence of transfusion-transmitted infectious agents allows us to visualize the regional epidemiological panorama of blood donors, which will generate new strategies for transfusion safety in recipients.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 2","pages":"e6588"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The hospital coordinator for organ and tissue donation for transplantation in Mexico: lessons from the British model].","authors":"Gerardo Rivera-Silva, María Guadalupe Moreno-Treviño, José F Yañez-Mijares","doi":"10.5281/zenodo.14616759","DOIUrl":"10.5281/zenodo.14616759","url":null,"abstract":"<p><p>The role of the Hospital Coordinator for Organ and Tissue Donation for Transplantation in Mexico is analyzed, using the British model as a reference. The lessons from the UK's experience in improving donation and transplantation rates are explored, emphasizing the importance of training, awareness, and collaboration. Additionally, the challenges Mexico faces in implementing an equivalent model are addressed, including cultural barriers and the need for a more robust management and coordination system. Adapting these experiences could strengthen the effectiveness of the donation process in the country.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 2","pages":"e6584"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Autosomal recessive limb-girdle muscular dystrophy-10. Case report].","authors":"Alan Alberto Pérez-Arzola, Daniela Juárez-Melchor, Israel Enrique Crisanto-López, Aurea Vera-Loaiza, Yazmin Hernández-Castañeda, Tania Alejandra Guzmán-Santiago, Berenice Jiménez-Pérez, Pablo Omar Rodríguez-Hurtado, Wilbert Salazar-Bonilla","doi":"10.5281/zenodo.14201220","DOIUrl":"10.5281/zenodo.14201220","url":null,"abstract":"<p><strong>Background: </strong>The autosomal recessive limb-girdle muscular dystrophy-10 (LGMDR10) is a muscular dystrophy caused by pathogenetic variants in the TTN gene encoding the titin protein, which is responsible for muscle flexibility and tension. Its prevalence is unknown. The main clinical manifestations are proximal muscle weakness predominantly in the shoulder girdle and pelvic girdle, mild weakness of distal muscles and muscle atrophy. The objective is to present a case report of autosomal recessive limb-girdle muscular dystrophy-10 in a Mexican patient.</p><p><strong>Clinical case: </strong>39-year-old male with hypotrophy of the left leg, muscle weakness of the 4 limbs predominantly proximal and asymmetrical, myalgia and nocturnal cramps. Total creatine phosphokinase level was of 819.7 IU/L, nerve conduction velocity and electromyography with left femoral neuropathy of the axonotmesis type and mixed axonal neuropathy with myopathic pattern of upper limbs. The molecular study for muscular dystrophies reported 2 pathogenic variants in compound heterozygous state in the TTN gene: c.107578C>T (p. Gln37860*) and c.104269C>T (p. Gln34767*), respectively.</p><p><strong>Conclusions: </strong>In line with the information available, there are no reported cases of LGMDR10 in Mexico. This is a progressive disease with total loss of ambulation between the fourth and the sixth decade of life, which is why its clinical suspicion is important for a timely diagnosis, an adequate counseling, and preventive measures of complications for a better quality of life.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e6447"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088016/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Ring chromosome 21 syndrome: report of 2 cases].","authors":"Tania Alejandra Guzmán-Santiago, Daniela Juárez-Melchor, Berenice Jiménez-Pérez, Aurea Vera-Loaiza, Alan Alberto Pérez-Arzola, Yazmin Hernández-Castañeda, Pablo Omar Rodríguez-Hurtado, Israel Enrique Crisanto-López, Luz María Garduño-Zarazúa, Wilbert Salazar-Bonilla","doi":"10.5281/zenodo.13381482","DOIUrl":"10.5281/zenodo.13381482","url":null,"abstract":"<p><strong>Background: </strong>When a chromosome undergoes 2 distal breaks and the broken ends join together, they form a ring chromosome. Ring 21 syndrome is described with a phenotype with minor dysmorphisms, thrombocytopenia, psychomotor and language delay. The objective of this work is to display 2 cases of male patients with ring chromosome 21.</p><p><strong>Clinical cases: </strong>The first case was a 5-year-old male patient, with psychomotor and language delay. Broad forehead with prominent metopic suture, bilateral epicanthic fold, hypotelorism, left esotropia, low-set asymmetrical pinnae, micrognathia, lower extremities with deep plantar folds. Karyotype 46,XY,r(21)(p11.2q21)[25]. The second case was an 8-year-old male patient with psychomotor and language delay. Skull with flattened occiput, triangular facies, midfacial flattening, palpebral fissures directed downwards, bilateral epicanthic fold, low-set and asymmetrical pinnae, micrognathia, prominent asymmetrical thorax on the right side, hands with irregular palmar folds. Karyotype: 46,XY,r(21)(p11q22)[25].</p><p><strong>Conclusion: </strong>Craniofacial dysmorphisms with psychomotor and language delay were the most relevant clinical data in both cases.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e6352"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Incidence of pulmonary thromboembolism in patients with COVID-19 pneumonia].","authors":"Ethel Raquel Felipe-Cardoso, Sadan Coronel-Hernández, Inés Álvarez-Ciaca, Adriana Bustos-Vadillo, Elisa Sánchez-Cabrera","doi":"10.5281/zenodo.14200009","DOIUrl":"https://doi.org/10.5281/zenodo.14200009","url":null,"abstract":"<p><strong>Background: </strong>COVID-19 disease is an infectious pathology which causes severe respiratory syndrome and it is caused by SARS-CoV-2. On the other hand, pulmonary thromboembolism is one of the most serious and insidious complications, although with a real incidence that is still unknown, especially in patients with COVID-19 pneumonia. Therefore, it is imperative to carry out research to know more information, as well as the relationship it could have with other comorbidities (the most frequent in our population) in order to establish early diagnosis and proper therapy.</p><p><strong>Objective: </strong>To determine the incidence of pulmonary thromboembolism by angiotomography in patients with COVID-19 pneumonia.</p><p><strong>Material and methods: </strong>An analytical, observational, longitudinal, single-center, retrospective and homodemic study was carried out. A total of 71 patients from a public hospital located in the city of Puebla, Mexico, were included.</p><p><strong>Results: </strong>It was determined a cumulative incidence of 0.09 of the patients studied. Male patients were the most affected, with an average age of 65 years. The trunk of the pulmonary artery was the most affected topographic site. Likewise, the most associated comorbidity was diabetes mellitus.</p><p><strong>Conclusions: </strong>There was a similar incidence to that obtained in studies carried out in other parts of the world.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e5752"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Mpox clade Ib: an inescapable global threat].","authors":"David Alejandro Cabrera-Gaytán, Alfonso Vallejos-Parás, Lumumba Arriaga-Nieto","doi":"10.5281/zenodo.14199959","DOIUrl":"10.5281/zenodo.14199959","url":null,"abstract":"<p><p>In 2024 it was reported that 92% of mpox cases from Africa were from the Democratic Republic of the Congo, and 66% of people diagnosed were juveniles under 15 years of age. In this outbreak, it is the clade I, in its variant Ib, and the transmission is more of heterosexual nature. In this editorial article some questions concerning this new mpox outbreak are made.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e6415"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-domain intervention program on cognitive function in community-dwelling older adults: Pilot study.","authors":"Rosalinda Sánchez-Arenas, Israel Grijalva, Leticia Manuel-Apolinar, Oscar Orihuela-Rodríguez, Lourdes Basurto-Acevedo, Irene Mujica-Morales, Mariela Bernabe-García, Arcelia Bernal-Diaz, Francisco Abraham Jiménez-Armenta, Eduardo Tapia-Fuentes, Daniela Hernández-González, Viviana Aparicio-Barranco, Yamileth Margarita Villarreal-López, Ryosuke Shigematsu","doi":"10.5281/zenodo.14200027","DOIUrl":"https://doi.org/10.5281/zenodo.14200027","url":null,"abstract":"<p><strong>Background: </strong>Recent interventions to prevent cognitive impairment include aerobic-cognitive training and educational programs on cognitive function.</p><p><strong>Objective: </strong>To compare the effectiveness of a multidomain intervention and a sports program (control) on objective cognitive function (OCF), subjective memory function (SMC), frontal assessment battery, cognitive reserve, depression, anxiety, and stress in older adults through a non-randomized study.</p><p><strong>Material and methods: </strong>The intervention consisted of aerobics and cognitive exercises (exercise on a checkered mat) and educational motivational support. The intervention group received 60 minutes of training 3 days a week for 24 weeks, and the control group 60 minutes of physical training 2 days a week for 24 weeks. Independent older adults were included. The baseline and final values of the outcome variables were obtained. The relative risk for SMC, as well as the median differences, the effect estimate, and ANCOVA for continuous variables were obtained.</p><p><strong>Results: </strong>The characteristics of the intervention group (n = 11) and control group (n = 10) were similar at baseline, except for age. OCF, SMC, and neuropsychological symptoms showed a positive trend in the intervention group, whereas in the control group did not. The intervention was significant in SMC (RR: 0.5; 95%CI 0.4-0.8), and the control showed a substantial decrease in OCF compared with the intervention group [F(1) = 8.4; p = 0.009; դp = 0.30].</p><p><strong>Conclusions: </strong>The results suggest that the 3-component program may be more effective than the control program in improving SMC and OCF.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e6406"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Incidence and factors associated with delirium in an Emergency Department].","authors":"Jorge Ayón-Aguilar, Laura Serrano-Vértiz, Fernando Vladimir Quiroz-Lara, Montserrat Torres-Macotela","doi":"10.5281/zenodo.14200014","DOIUrl":"https://doi.org/10.5281/zenodo.14200014","url":null,"abstract":"<p><strong>Background: </strong>Changes in cognition, attention, consciousness, and perception that occur rapidly and evolve unpredictably are the hallmarks of delirium syndrome. Out of hospitalized patients over the age of 65, 20% experience complications during their stay; in Mexico, the incidence is reported to be 12%.</p><p><strong>Objective: </strong>To determine the incidence and factors associated with delirium in an Emergency Department.</p><p><strong>Material and methods: </strong>Prospective study, with 169 patients over 65 years of age, of both sexes, admitted to an Emergency Department for medical and surgical reasons, from November 1, 2022 to April 30, 2023. The Confussion Assessment Method (CAM) scale was administered to them and the incidence of delirium was determined; descriptive and inferential analysis was carried out using chi-squared with a statistical significance ≤ 0.05.</p><p><strong>Results: </strong>There were 92 female patients (56.3%) with a median age of 77 years (65-90). The incidence of delirium was 43.8%. The comorbidities associated with delirium were infections in 22.48% (p = 0.774), arrhythmias in 7.10% (p = 0.551) and heart disease in 5.91% (p = 0.477).</p><p><strong>Conclusions: </strong>Delirium occurred with a higher incidence compared to that reported in national and international literature; no statistically significant association was found between the present pathologies and delirium.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e6385"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Tenckhoff catheter placed in bladder. Case and review].","authors":"José Francisco Camacho-Aguilera, Eduardo Rodríguez-Llamas, Erick Olivo Rosas-Palomares","doi":"10.5281/zenodo.14201126","DOIUrl":"10.5281/zenodo.14201126","url":null,"abstract":"<p><strong>Background: </strong>Stage 5 kidney disease requires renal function replacement therapy, either through hemodialysis or peritoneal dialysis. Among the complications related to the placement of a peritoneal dialysis catheter are the mechanical ones, that include flow obstruction, peritoneal fluid leak, hernias, inadequate catheter position or injury to an intra-abdominal organ. A rare complication is the accidental catheter placement in the urinary bladder. Bladder perforation is favored when there is incomplete emptying of the bladder, a surgical history, and alterations in the lower urinary tract. A case of bladder perforation after catheter placement and a review of this subject is presented.</p><p><strong>Clinical case: </strong>64-year-old female patient presented with Tenckhoff catheter dysfunction. She was scheduled for catheter removal and placement. During the start of the infusion of dialysis solution, the patient started to feel the urgent need to urinate. A simple abdominal tomography was requested, confirming the catheter in the bladder.</p><p><strong>Conclusion: </strong>The risk factors for bladder injury after catheter placement are diabetes, neurogenic bladder, urinary obstruction and previous abdominal surgeries. In the presence of them, a careful approach to the cavity must be made, including bladder catheterization in cases where complete bladder emptying is not guaranteed.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e6133"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Interleukins involved in bone degeneration from periodontal disease: Systematic review].","authors":"Yomira Salgado-Martínez, Magali González-Rodríguez, Rosina Eugenia Villanueva-Arriaga, Nelly Molina-Frechero","doi":"10.5281/zenodo.14200998","DOIUrl":"10.5281/zenodo.14200998","url":null,"abstract":"<p><p>An imbalance between the plaque biofilm and the host's immune system results in the overexpression of several proinflammatory interleukins, the spread of inflammation through the gums leading to the destruction of connective tissue and the subsequent destruction of the gingival tissue. Periodontal diseases are among the most common diseases, since they affect up to 50% of the world population. Often, the lower socioeconomic groups are the most affected, as well as the elderly. Interleukins play a fundamental role in the immune response and they are secreted by various cells, such as macrophages, mast cells, lymphocytes, etcetera. Due to the above, the objective was to carry out a systematic review of articles that relate interleukins and bone degeneration in periodontal disease, and this review was carried out in 4 databases: Scopus, PubMed, SciELO and Springerlink, using the keywords: Proflammatory interleukin and Periodontal disease, applying the following search strategy: IT ((interleukin) AND (periodontal disease or periodontitis) AND (bone)). The search gave a result of 12 scientific articles that corresponded to the topic, and obtained a good evaluation regarding the bias and quality of the article. We concluded that periodontal disease is complex and interleukins have been shown to establish a multidirectional link for the development of this disease.</p>","PeriodicalId":94200,"journal":{"name":"Revista medica del Instituto Mexicano del Seguro Social","volume":"63 1","pages":"e5592"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}