Acta cirurgica brasileira最新文献

{"title":"Study on the effect of Portulaca oleracea L. extract on chronic ulcerative colitis in rats induced by allogeneic antigen and acetic acid.","authors":"Yan Wu, Fang Zhao, Juan Zhao, Rong-Yao Ruan, Fei-Yan Wu, Yusheng Xu","doi":"10.1590/acb412126","DOIUrl":"10.1590/acb412126","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the effect and mechanism of Portulaca oleracea L. (POL) extract on acetic acid and alloantigen-induced chronic ulcerative colitis in rats.</p><p><strong>Methods: </strong>Ulcerative colitis was induced in rats by sensitization with rabbit colon antigen and acetic acid. Rats received oral sulfasalazine, intestine-quieting tablet, or POL (high, medium, or low dose) for 14 days. Disease activity index (DAI), colonic mucosal damage index (CMDI), and histological score (HS) were assessed. Serum levels of interleukin (IL)-4, IL-8, IL-17, C-reactive protein (CRP), immunoglobulin G (IgG), and interferon-γ (IFN-γ); colonic levels of myeloperoxidase (MPO), epidermal growth factor (EGF), and tumor necrosis factor (TNF)-α; serum hemolysin (by immunoturbidimetry); splenic T lymphocyte subsets (by flow cytometry); and serum IgG, IgM, IgA, C3, and C4 were measured.</p><p><strong>Results: </strong>Compared with the model group, POL significantly reduced DAI, CMDI, and HS scores in a dose-dependent manner-most markedly in the high-dose group (p < 0.01). POL also significantly decreased serum IL-8, IL-17, CRP, IFN-γ, and IgG, and colonic TNF-α and MPO (p < 0.05 or p < 0.01), while increasing serum IL-4 and colonic EGF (p < 0.01). All POL dosage groups significantly increased hemolysin, IgM, and CD4+CD25+/CD4+ levels in rats (p < 0.05 or p < 0.01), while decreasing serum IgG, IgA, complement C3/C4, CD4+/CD8+, and IL-17+ CD4+ (p < 0.05 or p < 0.01).</p><p><strong>Conclusion: </strong>The POL extract exerts therapeutic effects in chronic ulcerative colitis rats, likely by downregulating pro-inflammatory mediators-including IL-8, IL-17, CRP, IFN-γ, TNF-α, and MPO-, as well as serum IgG, IgA, C3/C4, CD4+/CD8+, and IL-17+ CD4+; and by upregulating anti-inflammatory/repair factors-including IL-4, EGF, lysozyme, IgM, and CD4+CD25+/CD4+. These findings support the clinical potential of POL for ulcerative colitis treatment.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e412126"},"PeriodicalIF":1.3,"publicationDate":"2026-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13167103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147950424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glaucocalyxin A enhances colonic anastomotic healing after ischemia-reperfusion: experimental findings.","authors":"Mehmet Algül, Bariş Rafet Karakaş, Oğuzhan Fatih Ay, Sadika Halide Akbaş, Arzu Karaveli, Kadir Balaban","doi":"10.1590/acb412526","DOIUrl":"10.1590/acb412526","url":null,"abstract":"<p><strong>Purpose: </strong>Glaucocalyxin A (GLA), a diterpenoid with antioxidative and anti-inflammatory properties, has shown vascular protective effects in preclinical models. This study aimed to evaluate whether GLA improves colonic anastomotic integrity following ischemia-reperfusion (I/R) injury.</p><p><strong>Methods: </strong>Twenty-four female Sprague Dawley rats were randomized into three groups (n = 8): control + GLA, I/R, and I/R + GLA. I/R was induced by 60-minute superior mesenteric artery occlusion and 60-minute reperfusion before end-to-end colonic anastomosis. GLA (10 mg/kg) was administered intraperitoneally. On postoperative day 7, anastomotic bursting pressure, adhesion scores, hydroxyproline, oxidative stress markers (total oxidative status, total antioxidant capacity, ischemia-modified albumin), and histopathology were evaluated.</p><p><strong>Results: </strong>The I/R + GLA group demonstrated significantly higher bursting pressure compared with the I/R group (126 versus 40 mmHg; p < 0.005). Tissue TOS levels were significantly lower in the I/R + GLA group compared with both other groups (p < 0.005). No significant differences were found in hydroxyproline levels, IMA values, or histopathological healing scores.</p><p><strong>Conclusion: </strong>GLA may support colonic anastomotic healing after I/R injury by reducing oxidative stress and could serve as a potential protective agent against anastomotic compromise.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e412526"},"PeriodicalIF":1.3,"publicationDate":"2026-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13167102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147950387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of xenografts with fish skin for the treatment of burns: a systematic review and meta-analysis.","authors":"Caio Placido Costa Arcanjo, Francisco Placido Nogueira Arcanjo, Luiz Odorico Monteiro de Andrade, Ivana Cristina de Holanda Cunha Barreto","doi":"10.1590/acb411326","DOIUrl":"10.1590/acb411326","url":null,"abstract":"<p><strong>Purpose: </strong>To conduct a systematic literature review and meta-analysis to assess the efficacy of fish skin xenografts in burn treatment, comparing reepithelialization time, pain reduction, and the amount of analgesics used.</p><p><strong>Methods: </strong>This review was designed and conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines and registered in PROSPERO under registration number CRD42023412250. The databases MEDLINE (via PubMed), Cochrane Library, Scientific Electronic Library Online (SciELO)/Latin American and Caribbean Health Sciences Literature (LILACS), and EMBASE were used. The literature search identified 768 articles. Through title and abstract screening, 736 were excluded, along with 16 duplicates. Sixteen articles were fully analyzed, of which six met the inclusion criteria for this review.</p><p><strong>Results: </strong>The systematic review found that patients treated with fish skin xenografts had shorter reepithelialization times and reduced pain compared to conventional treatments. The meta-analysis showed reduction in reepithelialization time for the intervention groups using fish skin grafts by 1.26 day (95% confidence interval [95%CI] -2.38 to -0.15; p < 0.00001) and a reduction in pain levels with score decreases of 3.84 (95%CI -6.42 to -1.26; p = 0.0009). The objective of assessing the number of analgesics used could not be evaluated quantitatively.</p><p><strong>Conclusion: </strong>The use of fish skin xenografts in burn patients is effective in reducing reepithelialization time and decreasing pain levels during treatment.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e411326"},"PeriodicalIF":1.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13120832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Educational innovation: mobile applications as complementary tools in the training of plastic surgery residents.","authors":"André Luiz Monteiro Dos Santos Marins, Matheus Galvão Valadares Bertolini Mussalem, Antônio de Pádua Peppe Neto, José da Conceição Carvalho Júnior, Lydia Masako Ferreira","doi":"10.1590/acb411926","DOIUrl":"10.1590/acb411926","url":null,"abstract":"<p><strong>Purpose: </strong>To identify and describe mobile applications that can serve as complementary tools in the education of plastic surgery residents.</p><p><strong>Methods: </strong>A structured literature review was conducted across MEDLINE, EMBASE, ERIC, Latin American and Caribbean Health Sciences Literature (LILACS), and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases. Search strategies used Medical Subject Headings (MeSH) terms and relevant keywords. Additional searches were performed in the App Store and Google Play to identify mobile applications related to plastic surgery education. Inclusion criteria covered studies and applications directly linked to residency training in plastic surgery.</p><p><strong>Results: </strong>Fourteen articles met eligibility criteria, and 18 mobile applications specifically related to plastic surgery education were identified. The majority was freely available and addressed topics such as surgical simulation, flap design, anatomy, and procedural guidance. Apps in English predominated across platforms.</p><p><strong>Conclusion: </strong>Mobile applications represent valuable complementary resources for plastic surgery training, supporting both theoretical learning and technical development. Their structured integration into residency curricula could enhance academic and clinical performance among residents.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e411926"},"PeriodicalIF":1.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13120788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of self-ligation of the spermatic cord and vas deferens in open orchiectomy of healthy adult crossbreed dogs: clinical assessment, infrared thermography, and inflammatory biomarkers.","authors":"Maurícia Elaine Pereira de Souza, Brunno Valença Oliveira, Ana Carolina Anchieta Adriano, Sarha Jane Evangelista Moura, Ed Johnny da Rosa Prado, Janice Keslen Neumann, Vinicius Dos Santos Rosa, Fernando do Carmo Silva, Sandro de Vargas Schons, Tadeu Filipe de Oliveira da Costa, Juliana Targino Silva Almeida E Macedo, Brenda Miranda Dias Januário, Ivan Felismino Charas Dos Santos","doi":"10.1590/acb412026","DOIUrl":"10.1590/acb412026","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the self-ligation of the spermatic cord and vas deferens in healthy adult dogs undergoing open orchiectomy, through clinical assessment, evaluation of acute inflammation, and surgeon satisfaction.</p><p><strong>Methods: </strong>Twenty adult male crossbreed dogs were included in the study and were randomly assigned to two groups of ten animals each. The SCT group underwent spermatic cord ligation using absorbable suture material, whereas, in the SCVT group, hemostasis was achieved through self-ligation involving the spermatic duct and vas deferens. The evaluated variables included clinical parameters, acute inflammatory biomarkers, inflammation at the surgical knot site via infrared thermography, surgical time, intraoperative bleeding, and surgeon satisfaction by using standardized scoring systems.</p><p><strong>Results: </strong>Surgical time was significantly shorter in the SCVT group compared to the SCT group (p = 0.021). The total leukocyte count was significantly higher (p = 0.01) in the SCVT group 24 hours after surgery.</p><p><strong>Conclusion: </strong>Both techniques proved to be safe and effective for open orchiectomy in healthy, medium-sized, crossbreed adult dogs. The SCVT was faster to perform, but it elicited a greater acute inflammatory response, as indicated by the increased total leukocyte count.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e412026"},"PeriodicalIF":1.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13120789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thymoquinone and caffeic acid phenethyl ester mitigate experimental ulcerative colitis: a biochemical and histopathological study.","authors":"Can Ersak, Ender Ergüder, Jafar Nouri Nojadeh, Saygin Altiner, Mevlut Recep Pekcici","doi":"10.1590/acb412226","DOIUrl":"10.1590/acb412226","url":null,"abstract":"<p><strong>Purpose: </strong>To establish an acetic acid-induced acute ulcerative colitis model in rats and to evaluate the clinical, biochemical, and histopathological effects of thymoquinone (TQ) and caffeic acid phenethyl ester (CAPE) in this model.</p><p><strong>Methods: </strong>Forty male Wistar albino rats (190-303 g) were randomly assigned to five groups (n = 8). All groups except the control received rectal acetic acid (4%) to induce colitis. Group 1 (control) received intraperitoneally (IP) 0.9% saline for five days. Group 2 (colitis) received IP 10% ethanol (vehicle for CAPE). Group 3 (TQ) received IP thymoquinone (10 mg/kg/day). Group 4 (CAPE) received IP caffeic acid phenethyl ester (10 µmol/kg/day). Group 5 (TQ+CAPE) received both agents at the same doses. On day 5, animals were euthanized, and colon and serum samples were collected for biochemical and histopathological analysis.</p><p><strong>Results: </strong>Significant differences were observed in the disease activity index, tumor necrosis factor-α, catalase, glutathione peroxidase, interleukin-10, and malondialdehyte indicating a balance between oxidant and antioxidant parameters. CAPE was found to have a greater anti-inflammatory effect than TQ histopathologically. The combined administration of CAPE and TQ mitigated oxidative stress as demonstrated by decreased oxidative stress biomarkers and improved antioxidant protection.</p><p><strong>Conclusion: </strong>Both CAPE and TQ demonstrated anti-inflammatory and antioxidant effects in an acetic acid-induced colitis model, with CAPE showing greater histological improvement. Their combined administration yielded additional benefits in oxidative stress reduction. These findings suggest that CAPE and TQ, particularly in combination, may hold promise as adjunctive agents in colitis management and warrant further investigation.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e412226"},"PeriodicalIF":1.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13120787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The beneficial effects of leave extract of Commiphora leptophloeos on intestinal mucositis induced by 5-fluorouracil in mice.","authors":"Amanda Silveira da Silva, Stephannie Jamyla de Araújo Barbosa, Susana Barbosa Ribeiro, Lucas Vinicius Souza de Carvalho, Rafaela Torres Dantas da Silva, Gerlane Coelho Bernardo Guerra, Raimundo Fernandes de Araújo Júnior, Nizyara Costa da Silva, Raphael Victor Silva Andrade, Gabrielle Marques de Paiva, Silvana Maria Zucolotto Langassner, Renato Dantas-Medeiros, Rafaela Alcindo Silva de Sousa Fé, Maria Laura de Souza Lima, Aurigena Antunes de Araújo","doi":"10.1590/acb411526","DOIUrl":"10.1590/acb411526","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effect of oral administration of a hydroethanolic extract of Commiphora leptophloeos leaves (CLF) on the progression of 5-fluorouracil (5-FU)-induced intestinal mucositis.</p><p><strong>Methods: </strong>Female Swiss mice were orally administered CLF at doses of 10, 100, or 300 mg/kg, or saline (negative control, NC), starting 30 minutes before intraperitoneal injection of 5-FU. A positive control (PC) group received 5-FU without CLF treatment. Treatment continued until euthanasia, three days after 5-FU injection. Body weight was monitored throughout the experiment. On day 4, small intestine tissue samples were collected for histopathological analysis. Duodenal tissue was also assessed for Muc-2 immunostaining.</p><p><strong>Results: </strong>In the CLF 10, 100 and 300 mg/kg groups, the duodenum histopathological score was 1 (1-1.5) p < 0.001, 1 (1-1.5) p < 0.01; 1 (1-1.25) p < 0.01, while the PC group score was 2 (2-2.75). Immunostaining analysis for Muc-2 revealed a score of 3 (3-3) in the CLF 10 group, compared to score 1.2 (0.8-1.6) in the PC group (p < 0.001), indicating that CLF 10 increased Muc-2 expression.</p><p><strong>Conclusion: </strong>The oral administration of a hydroethanolic extract of CLF protected the duodenal segment of Swiss mice from 5-FU-induced intestinal mucositis, likely by increasing mucin production.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e411526"},"PeriodicalIF":1.3,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13073033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147694178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of maternal arginine supplementation during lactation on offspring growth and wound healing in an experimental rat model of intrauterine malnutrition.","authors":"Ayrton Alves Aranha Junior, Jorge Eduardo Fouto Matias, Djanira Aparecida da Luz Veronez, Lucia de Noronha, João Carlos Repka, Rafaella Toledo Aranha, Antônio Carlos Ligocki Campos","doi":"10.1590/acb411626","DOIUrl":"10.1590/acb411626","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effects of maternal arginine-enriched diet during lactation, following gestational undernutrition, on offspring growth and wound healing.</p><p><strong>Methods: </strong>Pregnant Wistar rats were divided into two groups during gestation: control (C; ad libitum diet) and undernourished (Und; 60% of control diet). After delivery, the undernourished mothers were reassigned to two subgroups: ad libitum + Impact® (Arg) and ad libitum + Nutren® (Hh). Evaluated parameters included offspring anthropometric measurements, serum albumin, tensile strength, and collagen morphometry at the surgical wound. Statistical analyses included analysis of variance (ANOVA) and Tukey's, Student's t-test, and Fisher's test.</p><p><strong>Results: </strong>Maternal immunonutrition during lactation promoted recovery of offspring weight (C = 29.21 ± 2.86 g; Arg = 36.08 ± 5.38 g; p = 0.0009) and body length (C = 9.87 ± 0.32 cm; Arg = 10.91 ± 0.73 cm; p = 0.0008), shifting values from significantly lower at birth to higher than controls by weaning. Offspring healing parameters showed no significant differences compared with controls.</p><p><strong>Conclusion: </strong>An arginine-enriched diet provided to lactating rats malnourished during gestation significantly improved offspring anthropometric growth and supported wound healing following surgery at weaning.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e411626"},"PeriodicalIF":1.3,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13073036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147694164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of a folkloric plant extract in a rat partial nephrectomy model.","authors":"Ismail Ulus, Bulent Erol, Meftun Culpan, Sıdıka Seyma Ozkanli, Volkan Hanci, Turhan Caskurlu","doi":"10.1590/acb411026","DOIUrl":"10.1590/acb411026","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy and safety of Ankaferd in comparison with Arista and Surgiflo in a rat zero-ischemia partial nephrectomy model.</p><p><strong>Methods: </strong>A total of 28 Wistar albino rats were randomly assigned to four groups: control, Ankaferd, Arista, and Surgiflo. During partial nephrectomy, both the amount of bleeding and bleeding time were recorded. Intra-abdominal adhesions were evaluated on postoperative day 10. Nephrectomy specimens were harvested for histopathological assessment of tubular and glomerular necrosis, as well as for CD142 immunostaining.</p><p><strong>Results: </strong>Ankaferd demonstrated superior performance in terms of bleeding amount and bleeding time compared with both Arista and Surgiflo, although the differences did not reach statistical significance. Intra-abdominal adhesion scores were higher in the Ankaferd group than in the Arista and Surgiflo groups, with a statistically significant difference compared with the control group (p = 0.01). Histopathological analysis revealed a significantly higher glomerular necrosis score in the Ankaferd group compared with the control group (p = 0.043), while no significant differences were observed for tubular necrosis or CD142 immunohistochemical evaluation among the study groups.</p><p><strong>Conclusion: </strong>Ankaferd achieved more effective and rapid hemostasis than Arista and Surgiflo, but its higher adhesion scores limit its reliability for intra-abdominal use.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e411026"},"PeriodicalIF":1.3,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13007991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147517188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thoracic limb simulator for veterinary vascular access training.","authors":"Ana Clara Nogueira Espinha, Julia Piolla, Patrick Carmona Marinho, Yuri Karaccas de Carvalho","doi":"10.1590/acb411226","DOIUrl":"10.1590/acb411226","url":null,"abstract":"<p><strong>Purpose: </strong>To develop and validate a thoracic limb simulator for veterinary vascular access training (TSVT), focusing vein puncture in dogs.</p><p><strong>Methods: </strong>The simulator was designed, three-dimensional printed, and filled with silicone and resin. Five experienced veterinarians, with no prior simulator experience, performed procedures including hand positioning, vein palpation, antisepsis, venipuncture, catheter insertion, and access maintenance. Evaluators completed an anonymous questionnaire with a 3-point scale and provided qualitative feedback.</p><p><strong>Results: </strong>The TSVT accurately reproduced thoracic limb and cephalic vein. All professionals reported appropriate hand positioning, vein palpation, and antisepsis. Blood collection was feasible for all evaluators, while catheter insertion was feasible for four and partially feasible for one due to resistance within the simulated vessel. Fixation and maintenance of vascular access were successfully performed by all. The simulator allowed repeated practice without live animals, supporting safe and controlled development of psychomotor skills.</p><p><strong>Conclusion: </strong>These results demonstrated that the TSVT is effective for training cephalic vein puncture in dogs, faithfully reproducing anatomical structures and enabling acquisition of clinical and psychomotor skills in a safe, ethical, and repeatable manner, representing a valuable tool for veterinary education.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"41 ","pages":"e411226"},"PeriodicalIF":1.3,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13008400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147517392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}