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Mucosal Schwann Cell Hamartoma of the Appendix: Expanding the Differential for Gastrointestinal Bleeding. 阑尾粘膜雪旺细胞错构瘤：扩大胃肠道出血的鉴别鉴别。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-21 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001708
Abdulmalik Saleem, Taher Jamali, Iana Gueorguieva
{"title":"Mucosal Schwann Cell Hamartoma of the Appendix: Expanding the Differential for Gastrointestinal Bleeding.","authors":"Abdulmalik Saleem, Taher Jamali, Iana Gueorguieva","doi":"10.14309/crj.0000000000001708","DOIUrl":"10.14309/crj.0000000000001708","url":null,"abstract":"<p><p>Mucosal Schwann cell hamartomas (MSCH) are rare benign tumors typically found in the colorectal region. We present the case of an 87-year-old man with a history of mucosa-associated lymphoid tissue lymphoma who developed symptomatic gastrointestinal bleeding due to an appendiceal MSCH. The patient's ongoing melena and anemia led to further evaluation. Subsequent colonoscopy revealed active bleeding from the appendiceal orifice with hemostasis achieved using epinephrine injection. A laparoscopic appendectomy confirmed MSCH through histopathology and immunohistochemical staining. Given its rarity, this case underscores the importance of considering MSCH in unexplained gastrointestinal bleeding and demonstrates its potential to be a symptomatically significant entity.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01708"},"PeriodicalIF":0.6,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12094418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First Description of Simultaneous Sweet Syndrome and Tracheal Stenosis as Extraintestinal Manifestations in a Patient With Highly Active Ulcerative Colitis. 一例高度活动性溃疡性结肠炎患者同时出现Sweet综合征和气管狭窄的肠外表现。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-19 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001712
Hala Alrasheed, Oray Kahraman, Eva Markert, Olaf Chan-Hi Kim, Christin Pelzer, Katia Boggian, Stephan Brand, Samuel Truniger
{"title":"First Description of Simultaneous Sweet Syndrome and Tracheal Stenosis as Extraintestinal Manifestations in a Patient With Highly Active Ulcerative Colitis.","authors":"Hala Alrasheed, Oray Kahraman, Eva Markert, Olaf Chan-Hi Kim, Christin Pelzer, Katia Boggian, Stephan Brand, Samuel Truniger","doi":"10.14309/crj.0000000000001712","DOIUrl":"10.14309/crj.0000000000001712","url":null,"abstract":"<p><p>Sweet syndrome and tracheal stenosis are very rare extraintestinal manifestations of inflammatory bowel diseases. In this study, we present a patient with ulcerative colitis, who developed Sweet syndrome in combination with an acute tracheal stenosis causing a life-threatening situation requiring admission to the intensive care unit. The patient had an excellent response to intravenous corticosteroids and intravenous infliximab, which had to be switched to vedolizumab after an allergic reaction to infliximab. The patient remained in stable remission with vedolizumab. This is, to our knowledge, the first case reported, in which these very rare extraintestinal manifestations occurred simultaneously.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01712"},"PeriodicalIF":0.6,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12091659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Persistent Wound: Plasmablastic Lymphoma in a Perianal Fistula. 持续性伤口：肛周瘘管的浆母细胞淋巴瘤。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-17 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001705
Salim C Lutfallah, John F G Bobo, Rachna Jetly-Shridhar, Nisha Loganantharaj
{"title":"The Persistent Wound: Plasmablastic Lymphoma in a Perianal Fistula.","authors":"Salim C Lutfallah, John F G Bobo, Rachna Jetly-Shridhar, Nisha Loganantharaj","doi":"10.14309/crj.0000000000001705","DOIUrl":"10.14309/crj.0000000000001705","url":null,"abstract":"<p><p>Plasmablastic lymphoma is an aggressive subtype of diffuse large B-cell lymphoma associated with immunosuppression, particularly in HIV-positive patients. Although rare in HIV-negative individuals, patients with Crohn's disease experience immune dysregulation due to chronic immunosuppression that can predispose them to plasmablastic lymphoma. We present a case of a 54-year-old man with ileocolonic and perianal fistulizing Crohn's disease who developed plasmablastic lymphoma. This case emphasizes the importance of early recognition of plasmablastic lymphoma in patients undergoing chronic immunosuppressive treatment of Crohn's disease, as early diagnosis and timely intervention are crucial for improving outcomes.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01705"},"PeriodicalIF":0.6,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antitumor Necrosis Factor-Refractory Esophageal Lesions in Crohn's Disease Successfully Treated With Upadacitinib. Upadacitinib成功治疗克罗恩病的抗肿瘤坏死因子难治性食管病变。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-16 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001713
Naohiro Nakamura, Yusuke Honzawa, Yuka Ito, Yasuki Sano, Naoto Yagi, Eiko Saito, Norimasa Fukata, Makoto Naganuma
{"title":"Antitumor Necrosis Factor-Refractory Esophageal Lesions in Crohn's Disease Successfully Treated With Upadacitinib.","authors":"Naohiro Nakamura, Yusuke Honzawa, Yuka Ito, Yasuki Sano, Naoto Yagi, Eiko Saito, Norimasa Fukata, Makoto Naganuma","doi":"10.14309/crj.0000000000001713","DOIUrl":"10.14309/crj.0000000000001713","url":null,"abstract":"<p><p>A 39-year-old man with a 5-year history of ileocolonic Crohn's disease received treatment with 6-mercaptopurine and adalimumab. A computed tomography scan was performed due to a persistent cough, revealing esophageal wall thickening. Esophagogastroduodenoscopy identified multiple longitudinal ulcers throughout the esophagus. Despite infliximab treatment, the esophageal lesions deteriorated, leading to the initiation of upadacitinib for antitumor necrosis factor-refractory esophageal lesions. Consequently, all esophageal lesions were healed, and serum biomarkers returned negative results. Although upadacitinib is effective for patients with ileocolonic Crohn's disease, this is the first case demonstrating its efficacy for refractory esophageal lesions.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01713"},"PeriodicalIF":0.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
De novo Hepatitis B Virus Infection in a Post-transplant Patient Causing Stage 4 Cirrhosis Necessitating Retransplant. 移植后患者新发乙型肝炎病毒感染导致需要再次移植的4期肝硬化。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-16 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001704
Kevan Josloff, Benjamin Young, Marc Hersh, Alekya Bheemreddy, Sherry Lee, Dina Halegoua-Demarzio
{"title":"De novo Hepatitis B Virus Infection in a Post-transplant Patient Causing Stage 4 Cirrhosis Necessitating Retransplant.","authors":"Kevan Josloff, Benjamin Young, Marc Hersh, Alekya Bheemreddy, Sherry Lee, Dina Halegoua-Demarzio","doi":"10.14309/crj.0000000000001704","DOIUrl":"10.14309/crj.0000000000001704","url":null,"abstract":"<p><p>Hepatitis B virus (HBV) is a common cause of liver cirrhosis worldwide, almost always as a result of HBV infection at birth or a very young age. HBV very rarely causes cirrhosis when contracted as an adult. Notably, the risk of HBV progression to cirrhosis is higher in immunocompromised patients, such as liver transplant patients, although it is still quite rare. We present a liver-transplant patient who acquired a de novo HBV infection and developed HBV-associated cirrhosis requiring retransplantation.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01704"},"PeriodicalIF":0.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rectosigmoid Intussusception Due to a Nonmalignant Etiology: An Extremely Rare Cause of Acute Lower Gastrointestinal Bleeding in an Elderly Patient. 非恶性病因引起的直肠乙状结肠肠套叠：一种极为罕见的老年患者急性下消化道出血的病因。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-16 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001706
Kashif Ali, Samra Sohail, Grecia Dominguez Rivera, Valeska Balderas
{"title":"Rectosigmoid Intussusception Due to a Nonmalignant Etiology: An Extremely Rare Cause of Acute Lower Gastrointestinal Bleeding in an Elderly Patient.","authors":"Kashif Ali, Samra Sohail, Grecia Dominguez Rivera, Valeska Balderas","doi":"10.14309/crj.0000000000001706","DOIUrl":"10.14309/crj.0000000000001706","url":null,"abstract":"<p><p>An intussusception at the rectosigmoid junction with acute gastrointestinal bleeding is exceedingly rare. We present a case of an 88-year-old man who presented in the emergency department with bilateral lower quadrant abdominal pain and frank rectal bleeding for 2 days. A computed tomography abdomen pelvis angiogram with contrast showed a target sign, and a flexible sigmoidoscopy showed congested bowel, ischemia, frank blood, and intussusception at the rectosigmoid junction. He underwent an exploratory laparotomy with the removal of the affected part. The pathology and the peritoneal fluid cytology results came out negative for dysplasia and malignancy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01706"},"PeriodicalIF":0.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Duodenogastric Prolapse as a Rare Cause of Gastrointestinal Bleeding. 十二指肠胃脱垂是一种罕见的消化道出血原因。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-16 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001710
Clive Jude Miranda, Marcellus Anthony Singh, Fnu Monika, Ahmed Al-Chalabi
{"title":"Duodenogastric Prolapse as a Rare Cause of Gastrointestinal Bleeding.","authors":"Clive Jude Miranda, Marcellus Anthony Singh, Fnu Monika, Ahmed Al-Chalabi","doi":"10.14309/crj.0000000000001710","DOIUrl":"10.14309/crj.0000000000001710","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01710"},"PeriodicalIF":0.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Achalasia or Pseudoachalasia: Incidental Esophagogastric Junction Submucosal Leiomyoma During Peroral Endoscopic Myotomy. 贲门失弛缓症或假性贲门失弛缓症：经口内镜下肌切开术中偶然发生的食管胃交界处粘膜下平滑肌瘤。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-16 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001709
Kenan Rahima, Mohamad Hijazi, Mhd Kutaiba Albuni, Sogand Taheri, Venkata Muddana
{"title":"Achalasia or Pseudoachalasia: Incidental Esophagogastric Junction Submucosal Leiomyoma During Peroral Endoscopic Myotomy.","authors":"Kenan Rahima, Mohamad Hijazi, Mhd Kutaiba Albuni, Sogand Taheri, Venkata Muddana","doi":"10.14309/crj.0000000000001709","DOIUrl":"10.14309/crj.0000000000001709","url":null,"abstract":"<p><p>The concomitant presence of esophageal achalasia and esophagogastric junction submucosal leiomyoma is extremely rare. Peroral endoscopic myotomy has been endorsed as one of the primary interventions to manage esophageal achalasia. We present a 49-year-old woman who had initial endoscopic evaluation and diagnosis of achalasia type II then underwent peroral endoscopic myotomy and found to have incidental submucosal leiomyoma at 1 cm distal to esophagogastric junction. It was removed successfully by submucosal tunneling endoscopic resection. This poses the question of whether this is a case of achalasia or pseudoachalasia caused by leiomyoma.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01709"},"PeriodicalIF":0.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Upadacitinib as Rescue Therapy in a Pregnant Patient With IBD. Upadacitinib作为妊娠IBD患者的抢救治疗。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-14 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001701
Grace Geeganage, Duncan J Flynn, Sarah Martinez, Michelle J Wang, Melissa Spiel, Loren G Rabinowitz, Joseph D Feuerstein
{"title":"Upadacitinib as Rescue Therapy in a Pregnant Patient With IBD.","authors":"Grace Geeganage, Duncan J Flynn, Sarah Martinez, Michelle J Wang, Melissa Spiel, Loren G Rabinowitz, Joseph D Feuerstein","doi":"10.14309/crj.0000000000001701","DOIUrl":"https://doi.org/10.14309/crj.0000000000001701","url":null,"abstract":"<p><p>Upadacitinib is an oral Janus kinase inhibitor approved to treat moderate-to-severe ulcerative colitis. Studies have shown that upadacitinib is highly effective, though use has been limited in certain populations due to concerns of side effects. Outside of animal studies and rare case reports, there are little data for the safety of upadacitinib use in pregnancy. We report a case of a patient with left-sided ulcerative colitis recurrently exacerbated by pregnancies who responded to upadacitinib in her fourth pregnancy. Additional data will be helpful to establish the safety for Janus kinase inhibitors for treatment of inflammatory bowel disease patients during pregnancy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01701"},"PeriodicalIF":0.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Unique Case of a Successful Endoscopic Retrograde Cholangiopancreatography Through a Previously Placed Gastro-Jejunostomy Lumen Apposing Metal Stent. 通过先前放置的胃-空肠造口管腔对置金属支架成功的内镜逆行胆管造影的独特案例。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-10 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001703
Chloe Lahoud, Malek Kreidieh, Mohammad Abureesh, Youssef El Douaihy
{"title":"A Unique Case of a Successful Endoscopic Retrograde Cholangiopancreatography Through a Previously Placed Gastro-Jejunostomy Lumen Apposing Metal Stent.","authors":"Chloe Lahoud, Malek Kreidieh, Mohammad Abureesh, Youssef El Douaihy","doi":"10.14309/crj.0000000000001703","DOIUrl":"https://doi.org/10.14309/crj.0000000000001703","url":null,"abstract":"<p><p>Originally used for minimally invasive drainage of pancreatic fluid collections, the uses of lumen-apposing metal stents (LAMS) have expanded to encompass several other pathologies including gastric outlet obstruction, strictures, and cases with surgically altered anatomy. We describe a rare case of an endoscopic retrograde cholangiopancreatography that was successfully completed through a previously placed LAMS between the stomach and the jejunum, in a patient with challenging anatomy due to progressing malignancy resulting in gastric outlet obstruction. This case highlights the technical complexity of performing endoscopic retrograde cholangiopancreatography through a previously placed LAMS and underscores the importance of patient-centered care with readiness for adaptability in complex cases.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01703"},"PeriodicalIF":0.6,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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