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From Glycemic Control to Gut Telescoping: Intussusception in a Patient on a Glucagon-Like Peptide-1 Receptor Agonist. 从血糖控制到肠道伸缩：胰高血糖素样肽-1受体激动剂患者肠套叠。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-25 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001679
Bianca Thakkar, Minh Thu T Nguyen, Rachael Hagen, Neil Parikh
{"title":"From Glycemic Control to Gut Telescoping: Intussusception in a Patient on a Glucagon-Like Peptide-1 Receptor Agonist.","authors":"Bianca Thakkar, Minh Thu T Nguyen, Rachael Hagen, Neil Parikh","doi":"10.14309/crj.0000000000001679","DOIUrl":"https://doi.org/10.14309/crj.0000000000001679","url":null,"abstract":"<p><p>Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely utilized for managing diabetes and obesity due to their efficacy in improving glycemic control and promoting weight loss. However, their gastrointestinal effects, such as slowed motility, may lead to adverse outcomes, including small bowel obstruction. Intussusception, a rare complication in adults, has been sparsely reported with GLP-1RA use. We present a 32-year-old woman with iron deficiency anemia who was incidentally diagnosed with transient small bowel intussusception on computed tomography enterography while on semaglutide therapy. No evidence of obstruction or pathological lead point was identified, and follow-up imaging showed resolution without intervention. This case suggests a possible link between GLP-1RA therapy and intussusception, likely secondary to altered gastrointestinal motility. Clinicians should remain vigilant for rare complications associated with GLP-1RAs, particularly in patients presenting with gastrointestinal symptoms. Further studies are warranted to elucidate this association.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01679"},"PeriodicalIF":0.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12026376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Triple A Syndrome-A Rare Hereditary Cause of Achalasia. 三A综合征——贲门失弛缓症的罕见遗传原因。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-25 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001686
Shivangini Duggal, Monica Botros, Emerald Zaw, Swati Mahapatra, Jesus Guzman, Keith Garrison, Richard Mccallum
{"title":"Triple A Syndrome-A Rare Hereditary Cause of Achalasia.","authors":"Shivangini Duggal, Monica Botros, Emerald Zaw, Swati Mahapatra, Jesus Guzman, Keith Garrison, Richard Mccallum","doi":"10.14309/crj.0000000000001686","DOIUrl":"https://doi.org/10.14309/crj.0000000000001686","url":null,"abstract":"<p><p>Triple A syndrome (TAS) is a rare disorder inherited in an autosomal recessive manner. It is characterized by the triad of alacrimia, achalasia, and adrenal insufficiency. It is caused by mutations in the <i>AAAS</i> gene (achalasia-addisonianism-alacrima syndrome), which disrupts the protein ALADIN (Alacrima-Achalasia-Adrenal insufficiency Neurologic disorder protein), which plays an important role in nucleocytoplasmic transport and cellular stress response. Unlike the presented cases, most patients with TAS present in early childhood with various symptoms including dry eyes, difficulty swallowing, and recurrent infections in addition to signs of adrenal crisis such as hypotension, hypoglycemia, and hyperpigmentation. Diagnosis can be achieved by genetic testing, revealing the mutations in the <i>AAAS</i> gene. Management of TAS mainly focuses on addressing each condition separately such as prescribing artificial tears for alacrimia, glucocorticoid replacement therapy for adrenal insufficiency, and performing pneumatic dilation or surgical intervention for achalasia. Early diagnosis is crucial for improving quality of life and minimizing the morbidity and mortality linked to the syndrome.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01686"},"PeriodicalIF":0.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12026375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Case of Tacrolimus-Induced Acute Pancreatitis in a Liver Transplant Recipient. 他克莫司致肝移植受者急性胰腺炎的罕见病例。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-25 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001659
Renan Prado, Arjun Chatterjee, Zurabi Zaalishvili, Rupayan Kundu, Shilpa Junna, Shreya Sengupta, Nizar Zein, Syed A Mohiuddin
{"title":"Rare Case of Tacrolimus-Induced Acute Pancreatitis in a Liver Transplant Recipient.","authors":"Renan Prado, Arjun Chatterjee, Zurabi Zaalishvili, Rupayan Kundu, Shilpa Junna, Shreya Sengupta, Nizar Zein, Syed A Mohiuddin","doi":"10.14309/crj.0000000000001659","DOIUrl":"https://doi.org/10.14309/crj.0000000000001659","url":null,"abstract":"<p><p>Tacrolimus-induced acute pancreatitis (TAP) is rare and requires thorough evaluation, including genetic testing, to rule out other causes. While TAP has been documented in a few cases following kidney transplantation, we report the first case of TAP in an adult after liver transplantation, with a noteworthy feature of late-onset TAP occurring more than 12 months after initiating tacrolimus therapy. This case highlights the potential for delayed onset of TAP, and we suggest that tacrolimus may warrant reclassification from category III to Ic in the drug-induced pancreatitis classification. In addition, we introduce sirolimus as a viable alternative for immunosuppression following TAP.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01659"},"PeriodicalIF":0.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12026453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolated Metachronous Intraluminal Colonic Metastasis in Carcinoma Gall Bladder: The Path Less Trodden. 离体异时性胆囊癌腔内结肠转移：较少涉足的途径。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-25 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001683
Abhijna Soori, Raja Kalayarasan, Pothugunta Saikrishna, Pazhanivel Mohan, B H Srinivas, Biju Pottakkat
{"title":"Isolated Metachronous Intraluminal Colonic Metastasis in Carcinoma Gall Bladder: The Path Less Trodden.","authors":"Abhijna Soori, Raja Kalayarasan, Pothugunta Saikrishna, Pazhanivel Mohan, B H Srinivas, Biju Pottakkat","doi":"10.14309/crj.0000000000001683","DOIUrl":"https://doi.org/10.14309/crj.0000000000001683","url":null,"abstract":"<p><p>Gallbladder cancer (GBC) is characterized by late presentation, early systemic spread, and poor long-term survival. A 65-year-old woman presented with isolated intraluminal colonic metastasis 46 months after radical surgery for GBC. The patient also underwent subtotal cholecystectomy 12 years before the diagnosis of GBC. In view of gastrointestinal bleeding, the patient underwent laparoscopic transverse colectomy with colocolic anastomosis. Metachronous isolated intraluminal colonic metastasis is being reported for the first time in English literature. The possible routes of colonic metastasis and its optimum management in the metachronous setting are discussed in this report.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01683"},"PeriodicalIF":0.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12026371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colonic Stenting Before Endoscopic Ultrasound-Guided Enterocolostomy in Malignant Small Bowel Obstruction. 超声内镜引导下恶性小肠梗阻肠结肠造口术前结肠支架植入术。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-19 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001671
Ritik Mahaveer Goyal, Sameer Rao, Anand Shah, Shivani Patel, Imran Qureshi, Ahmed Al-Khazraji, Kaveh Hajifathalian
{"title":"Colonic Stenting Before Endoscopic Ultrasound-Guided Enterocolostomy in Malignant Small Bowel Obstruction.","authors":"Ritik Mahaveer Goyal, Sameer Rao, Anand Shah, Shivani Patel, Imran Qureshi, Ahmed Al-Khazraji, Kaveh Hajifathalian","doi":"10.14309/crj.0000000000001671","DOIUrl":"https://doi.org/10.14309/crj.0000000000001671","url":null,"abstract":"<p><p>Malignant Small Bowel Obstruction (MSBO) is a debilitating complication of intra-abdominal malignancies, characterized by symptoms such as intractable nausea, vomiting, and abdominal pain. Surgical intervention may become necessary for symptom management if conservative measures fail, although it carries a significant risk of postoperative morbidity. Endoscopic ultrasound-guided enterocolostomy is an emerging alternative for palliative management of MSBO when other surgical or endoscopic interventions are not feasible or have failed. We present a case of a 50-year-old woman with MSBO secondary to metastatic squamous cell carcinoma of cervix who required the placement of a luminal colonic stent in the sigmoid colon before undergoing endoscopic ultrasound-guided enterocolostomy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01671"},"PeriodicalIF":0.6,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12011569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Tissue Remodeling for a More Homogenous Ablation in Transoral Outlet Reduction Using Suturing and Noncontact Argon Plasma Coagulation. 修正：使用缝合和非接触氩等离子体凝固在经口出口复位中进行更均匀消融的组织重塑。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-19 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001697
Leandro Sierra, Arjun Chatterjee, Akash Khurana, Renan Prado, Roma Patel, Stephen A Firkins, Roberto Simons-Linares
{"title":"Correction to: Tissue Remodeling for a More Homogenous Ablation in Transoral Outlet Reduction Using Suturing and Noncontact Argon Plasma Coagulation.","authors":"Leandro Sierra, Arjun Chatterjee, Akash Khurana, Renan Prado, Roma Patel, Stephen A Firkins, Roberto Simons-Linares","doi":"10.14309/crj.0000000000001697","DOIUrl":"https://doi.org/10.14309/crj.0000000000001697","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.14309/crj.0000000000001631.].</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01697"},"PeriodicalIF":0.6,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12011564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Cause of an Endoscopic Retrograde Cholangiopancreatography Surprise of "Concertina Effect" in Chronic Pancreatitis: Pancreatico-Jejunal Fistula. 慢性胰腺炎内窥镜逆行胰胆管造影“手风琴效应”的罕见原因：胰空肠瘘。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-19 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001681
Jahnvi Dhar, Roshan Agarwala, Saroj Kant Sinha, Jayanta Samanta
{"title":"A Rare Cause of an Endoscopic Retrograde Cholangiopancreatography Surprise of \"Concertina Effect\" in Chronic Pancreatitis: Pancreatico-Jejunal Fistula.","authors":"Jahnvi Dhar, Roshan Agarwala, Saroj Kant Sinha, Jayanta Samanta","doi":"10.14309/crj.0000000000001681","DOIUrl":"https://doi.org/10.14309/crj.0000000000001681","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01681"},"PeriodicalIF":0.6,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12011568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapidly Fatal Metastatic Cholangiocarcinoma Associated With Metabolic Dysfunction-Associated Steatotic Liver Disease and Metabolic Syndrome: A Case Report Highlighting Emerging Risk Factors. 与代谢功能障碍相关的脂肪变性肝病和代谢综合征相关的快速致命转移性胆管癌：一个突出新出现的危险因素的病例报告。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-16 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001676
Joel Konlack, Akil Olliverrie, Nitin Pendyala, Joseph Yvan Bena, Guy Loic Nguefang, Nikisha Pandya, Christopher Chum
{"title":"Rapidly Fatal Metastatic Cholangiocarcinoma Associated With Metabolic Dysfunction-Associated Steatotic Liver Disease and Metabolic Syndrome: A Case Report Highlighting Emerging Risk Factors.","authors":"Joel Konlack, Akil Olliverrie, Nitin Pendyala, Joseph Yvan Bena, Guy Loic Nguefang, Nikisha Pandya, Christopher Chum","doi":"10.14309/crj.0000000000001676","DOIUrl":"https://doi.org/10.14309/crj.0000000000001676","url":null,"abstract":"<p><p>Cholangiocarcinoma (CCA), a rare biliary cancer, typically presents with nonspecific symptoms that hinder early diagnosis. Emerging metabolic risk factors are increasingly being recognized as contributors. We present the case of a 54-year-old woman with newly diagnosed metabolic dysfunction-associated steatotic liver disease and metabolic syndrome, who presented with acute abdominal pain and a subsequent liver biopsy-confirmed intrahepatic CCA. Despite chemotherapy and immunotherapy, rapid disease progression led to metastasis and systemic complications, resulting in death. This case highlights the aggressive nature of CCA and the importance of addressing modifiable metabolic risk factors to improve the outcomes.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01676"},"PeriodicalIF":0.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12002370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Closure of a Large Rectal Perforation Secondary to an Unusual Foreign Body Using Endoscopic Clip and Loop Technique (King Closure). 使用内窥镜夹环技术成功闭合一个由不寻常异物引起的直肠大穿孔（King闭合）。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-16 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001678
Jahnvi Dhar, Deshidi Srinu, Antriksh Kumar, Ishita Laroiya, Jayanta Samanta
{"title":"Successful Closure of a Large Rectal Perforation Secondary to an Unusual Foreign Body Using Endoscopic Clip and Loop Technique (King Closure).","authors":"Jahnvi Dhar, Deshidi Srinu, Antriksh Kumar, Ishita Laroiya, Jayanta Samanta","doi":"10.14309/crj.0000000000001678","DOIUrl":"https://doi.org/10.14309/crj.0000000000001678","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01678"},"PeriodicalIF":0.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12002373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eosinophilic Esophageal Myositis. 嗜酸性食管肌炎。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-16 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001663
Ajay Pranami, Amol Dahale, Abhijeet Karad, Raghavender Puri, Prashant Gopal, Debabrata Banerjee
{"title":"Eosinophilic Esophageal Myositis.","authors":"Ajay Pranami, Amol Dahale, Abhijeet Karad, Raghavender Puri, Prashant Gopal, Debabrata Banerjee","doi":"10.14309/crj.0000000000001663","DOIUrl":"https://doi.org/10.14309/crj.0000000000001663","url":null,"abstract":"<p><p>Eosinophilic esophageal myositis (EoEM) is a rare condition affecting the muscularis propria without any involvement of the squamous epithelium or submucosa. Patients may present with chest pain, dysphagia, weight loss, or recurrent episodes of food impaction. Similar symptoms are also seen in eosinophilic esophagitis making the diagnosis difficult. Endoscopic ultrasound helps define muscularis propria layer involvement and allows for deeper biopsy. Early diagnosis is essential as EoEM can be treated medically, although surgical and endoscopic interventions might be required. We encountered a 73-year-old man with EoEM diagnosed with endoscopic ultrasound and successfully treated with steroids.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01663"},"PeriodicalIF":0.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12002388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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