ACG Case Reports JournalPub Date : 2024-11-09eCollection Date: 2024-11-01DOI: 10.14309/crj.0000000000001552
Mark Zemanek, Joseph Carter Powers, Katherine Westbrook, Emma Dester, Riley Smith, Taha Qazi
{"title":"Rare Metastasis of Prostate Cancer in a Man With Ulcerative Colitis After Creation of an Ileal Pouch.","authors":"Mark Zemanek, Joseph Carter Powers, Katherine Westbrook, Emma Dester, Riley Smith, Taha Qazi","doi":"10.14309/crj.0000000000001552","DOIUrl":"https://doi.org/10.14309/crj.0000000000001552","url":null,"abstract":"<p><p>Prostate cancer is one of the most common globally diagnosed cancers in men. It most frequently metastasizes to bones, lymph nodes, lungs, or the liver. There are limited data investigating the impact of prostate cancer on patients who have undergone ileal pouch-anal anastomosis. We explore the case and the diagnosis of a 68-year-old man with prostate adenocarcinoma that metastasized to the ileal pouch and ultimately required pouch explant. In addition, we discuss the challenges associated with screening and treating prostate cancer in patients with ileal pouch-anal anastomosis.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 11","pages":"e01552"},"PeriodicalIF":0.6,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-11-09eCollection Date: 2024-11-01DOI: 10.14309/crj.0000000000001545
Xiao-Tong Hu, Dong Wang
{"title":"A Delayed Postoperative Anastomotic Submucosal Abscess.","authors":"Xiao-Tong Hu, Dong Wang","doi":"10.14309/crj.0000000000001545","DOIUrl":"https://doi.org/10.14309/crj.0000000000001545","url":null,"abstract":"<p><p>Delayed anastomotic submucosal abscess is a rare complication of rectal tumor resection. A submucosal tumor-like lesion near the anastomotic site was detected in a 57-year-old woman, and pus and sutures were found through spontaneously formed fistulas. Endoscopic ultrasound confirmed the presence of hyperechoic pus flowing out from the fistulas on compression of the lesion. The patient recovered well without surgery. This case indicates that submucosal abscess should be taken into consideration if suspected submucosal tumor-like lesions are detected after rectal surgery. Endoscopic drainage combined with antibiotic treatment may be an effective strategy for limited postoperative anastomotic abscess.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 11","pages":"e01545"},"PeriodicalIF":0.6,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-11-06eCollection Date: 2024-11-01DOI: 10.14309/crj.0000000000001546
David Choi, Benjamin McDonald, David T Rubin
{"title":"Immediate Infusion Reaction to Intravenous Risankizumab-rzaa but Subsequent Tolerance to Subcutaneous Risankizumab-rzaa.","authors":"David Choi, Benjamin McDonald, David T Rubin","doi":"10.14309/crj.0000000000001546","DOIUrl":"10.14309/crj.0000000000001546","url":null,"abstract":"<p><p>Risankizumab-rzaa (RZA) is a fully human immunoglobulin G monoclonal antibody (Mab) which has fewer immunogenic concerns compared with chimeric Mabs. The pivotal trials of RZA found no significant differences in infusion reactions between drug and placebo. This case illustrates successful transition to subcutaneous RZA following a serious hypersensitivity reaction to intravenous RZA.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 11","pages":"e01546"},"PeriodicalIF":0.6,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11540427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-11-06eCollection Date: 2024-11-01DOI: 10.14309/crj.0000000000001551
David Bayless, Jasraj Singh, Byoung Uk Park, Seth Sweetser
{"title":"Tirzepatide-Associated Colonic Ischemia.","authors":"David Bayless, Jasraj Singh, Byoung Uk Park, Seth Sweetser","doi":"10.14309/crj.0000000000001551","DOIUrl":"10.14309/crj.0000000000001551","url":null,"abstract":"<p><p>The use of the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist tirzepatide has markedly increased for the treatment of weight loss and management of diabetes mellitus. Gastrointestinal adverse effects of GLP-1/GIP agonist therapy, including nausea, vomiting, and constipation, are common. We report a case of colonic ischemia in a 62-year-old woman which developed in association with the use of tirzepatide for weight loss. This report highlights a potential risk relationship between GLP-1/GIP agonist therapy and colonic ischemia and identifies risk factors that should be considered before prescribing tirzepatide.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 11","pages":"e01551"},"PeriodicalIF":0.6,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11540430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-11-06eCollection Date: 2024-11-01DOI: 10.14309/crj.0000000000001544
Jeremy A Klein, Joëlle St-Pierre, David Choi, Jacqueline Lopez, David T Rubin
{"title":"Dramatic Changes in Thiopurine Metabolite Levels in a Patient With Inflammatory Bowel Disease Treated With Tirzepatide for Weight Loss.","authors":"Jeremy A Klein, Joëlle St-Pierre, David Choi, Jacqueline Lopez, David T Rubin","doi":"10.14309/crj.0000000000001544","DOIUrl":"10.14309/crj.0000000000001544","url":null,"abstract":"<p><p>Thiopurines can be used to maintain remission in patients with inflammatory bowel disease. Thiopurines require regular blood count monitoring and, in specific patients, thiopurine metabolites for assessment of optimization and safety. We present the case of a 42-year-old woman with ulcerative colitis postcolectomy and ileal pouch-anal anastomosis with subsequent antibiotic-resistant diffuse pouchitis and prepouch ileitis. She was in stable remission with thiopurine monotherapy. Following tirzepatide initiation, she experienced elevated liver enzymes associated with a significant increase in thiopurine metabolite levels. This case underlines the importance of monitoring metabolite levels in patients with inflammatory bowel disease initiated on glucagon-like peptide 1-targeted therapies.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 11","pages":"e01544"},"PeriodicalIF":0.6,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11540429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-11-06eCollection Date: 2024-11-01DOI: 10.14309/crj.0000000000001543
Juan Sebastián Frías-Ordoñez, Martín Alonso Garzón Olarte, Geovanny Hernández-Cely
{"title":"SpyBite-Assisted Biliary Cannulation Facilitating Endoscopic Retrograde Cholangiopancreatography in the Presence of Intradiverticular Papilla.","authors":"Juan Sebastián Frías-Ordoñez, Martín Alonso Garzón Olarte, Geovanny Hernández-Cely","doi":"10.14309/crj.0000000000001543","DOIUrl":"10.14309/crj.0000000000001543","url":null,"abstract":"<p><p>Biliary cannulation in the context of intradiverticular papilla (IDP) during endoscopic retrograde cholangiopancreatography (ERCP) remains a challenge even for experts. A 71-year-old woman with choledocholithiasis failed extrainstitutional ERCP because of the presence of IDP. A new ERCP was performed, identifying papillary orifice at the edge of the diverticulum, biliary cannulation by means of SpyBite and sphincterotome, visualizing intra and extrahepatic bile duct dilatation, proceeding to large balloon bilioplasty with extraction of biliary sludge, with optimal results and without complications. This strategy was effective and safe. It could be recommended for difficult cannulation in the presence of IDP.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 11","pages":"e01543"},"PeriodicalIF":0.6,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11540428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Granulomatous Colitis Due to Hermansky-Pudlak Syndrome.","authors":"Hajar Koulali, Samira Azzmouri, Mariam Tajir, Khawla Zerrouki, Anass Haloui, Ouiam Elmqaddem, Abdelkrim Zazour, Zahi Ismaili, Ghizlane Kharrasse","doi":"10.14309/crj.0000000000001477","DOIUrl":"10.14309/crj.0000000000001477","url":null,"abstract":"<p><p>Hermansky-Pudlak syndrome (HPS) is a rare genetic disorder characterized by oculocutaneous albinism, bleeding diathesis, and multiorgan involvement. Granulomatous enterocolitis may occur in a subset of patients. Distinguishing HPS from other diseases such as Crohn's disease can be challenging, and managing HPS-associated colitis is complex. Recent reports suggest potential efficacy of infliximab in treating HPS-related granulomatous colitis. Here, we document the case of a 27-year-old patient with genetically confirmed HPS type 1, presenting with granulomatous colitis and successfully treated with corticosteroids and infliximab.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 11","pages":"e01477"},"PeriodicalIF":0.6,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11527421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142566797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-10-31eCollection Date: 2024-11-01DOI: 10.14309/crj.0000000000001547
Carlo Maria Rossi, Marco Vincenzo Lenti, Antonio Lo Bello, Stefania Merli, Alessandro Vanoli, Andrea Anderloni, Antonio Di Sabatino
{"title":"Pinworm Infection Misdiagnosed With Primary Eosinophilic Colitis. A Case Series.","authors":"Carlo Maria Rossi, Marco Vincenzo Lenti, Antonio Lo Bello, Stefania Merli, Alessandro Vanoli, Andrea Anderloni, Antonio Di Sabatino","doi":"10.14309/crj.0000000000001547","DOIUrl":"10.14309/crj.0000000000001547","url":null,"abstract":"<p><p>Parasitic infections make it difficult to establish a diagnosis of primary eosinophilic gastrointestinal disorders (EGID), may even co-occur with inflammatory bowel disease and complicate the management of patients treated with immunosuppressants. Yet, pinworm infection is often ignored as a cause of mucosal eosinophilia. We described 3 cases where pinworm infection was initially misdiagnosed as primary EGID. No current guideline is available for EGID in adult patients, while for patients with inflammatory bowel disease, parasitic infection screening is recommended only in some subset of patients. A more comprehensive and precise recommendation regarding the parasitic species to consider and the diagnostic tests to order is currently lacking.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 11","pages":"e01547"},"PeriodicalIF":0.6,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142566907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-10-31eCollection Date: 2024-11-01DOI: 10.14309/crj.0000000000001548
Ahmad Alomari, Mark Obri, Basel Aldroubi, Muhammad Zarrar Khan, Ammad Chaudhary, Ismail Althunibat, Cyrus Piraka, Tobias Zuchelli
{"title":"Hybrid Endoscopic Submucosal Dissection for Isolated Gastric Metastasis of Renal Cell Carcinoma.","authors":"Ahmad Alomari, Mark Obri, Basel Aldroubi, Muhammad Zarrar Khan, Ammad Chaudhary, Ismail Althunibat, Cyrus Piraka, Tobias Zuchelli","doi":"10.14309/crj.0000000000001548","DOIUrl":"10.14309/crj.0000000000001548","url":null,"abstract":"<p><p>Metastasis to the stomach is a rare occurrence, especially from renal cell carcinoma (RCC). We report a case of a 76-year-old man with a history of RCC, in remission for 11 years postnephrectomy, who presented with gastrointestinal symptoms, was found to have a 2 cm gastric mass confirmed as metastatic RCC. Endoscopic submucosal dissection was attempted, but due to the hypervascular nature of the mass, a hybrid endoscopic submucosal dissection was performed, achieving complete resection. Follow-up at 7 months showed no recurrence, highlighting the potential for endoscopic treatment options for isolated gastric metastasis, despite the lack of specific guidelines.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 11","pages":"e01548"},"PeriodicalIF":0.6,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11527420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142566805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-10-24eCollection Date: 2024-10-01DOI: 10.14309/crj.0000000000001541
Francisco Alejandro Félix-Téllez, Raúl Alberto Jiménez-Castillo, José María Remes-Troche
{"title":"Identifying the Hiccup-Induced Esophagogastric Waveform: A Case Series Report Using High-Resolution Manometry.","authors":"Francisco Alejandro Félix-Téllez, Raúl Alberto Jiménez-Castillo, José María Remes-Troche","doi":"10.14309/crj.0000000000001541","DOIUrl":"https://doi.org/10.14309/crj.0000000000001541","url":null,"abstract":"<p><p>Hiccups result from involuntary contractions of the diaphragm, driven by a complex neuromuscular reflex. Three patients with persistent hiccups underwent esophageal high-resolution manometry during hiccup episodes, revealing a consistent finding: sustained contraction of the esophagogastric junction with intermittent pressure peaks. This pattern, termed the \"Hiccup-Induced Esophagogastric Waveform,\" shows significant esophageal pressure changes linked to hiccup reflex. It may reflect a compensatory mechanism to expel excess esophageal residue or gas. These findings suggest hiccups could exacerbate symptoms of esophageal disorders, such as dysphagia and chest pain, and highlight the need for targeted therapeutic strategies. Further research is needed to explore these mechanisms.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 10","pages":"e01541"},"PeriodicalIF":0.6,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11500770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}