ACG Case Reports JournalPub Date : 2025-01-17eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001598
Sangkyu Noh, Franklin Liu, Samuel H Cheong, Sasha Taleban
{"title":"Rare Finding of Rectal Squamous Metaplasia in Inflammatory Bowel Disease.","authors":"Sangkyu Noh, Franklin Liu, Samuel H Cheong, Sasha Taleban","doi":"10.14309/crj.0000000000001598","DOIUrl":"https://doi.org/10.14309/crj.0000000000001598","url":null,"abstract":"<p><p>Rectal squamous metaplasia in inflammatory bowel disease is rare. We present 2 cases of rectal squamous metaplasia, one in a patient with Crohn's disease and another with ulcerative colitis. Given the risk of malignant transformation, dysplasia surveillance is important particularly in areas of chronic inflammation. Furthermore, human papilloma virus (HPV) is involved in the pathogenesis of anal squamous cell carcinoma (SCC), but no guidelines exist in the United States for HPV prophylaxis against anal SCC in inflammatory bowel disease. HPV vaccination should be considered in high-risk patients younger than 45 years for prevention of anal SCC, including those with rectal squamous metaplasia.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01598"},"PeriodicalIF":0.6,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11741210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-10eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001588
Abigail Layton Ellington, Samuel Thierjung Tarry, Matthew Nigel Hugh Ellis, Steven B Clayton
{"title":"Situational Syncope Triggered by Swallowing.","authors":"Abigail Layton Ellington, Samuel Thierjung Tarry, Matthew Nigel Hugh Ellis, Steven B Clayton","doi":"10.14309/crj.0000000000001588","DOIUrl":"10.14309/crj.0000000000001588","url":null,"abstract":"<p><p>Syncope is characterized by a transient loss of consciousness. Swallow syncope, a rare cause of syncope, is caused by vagus nerve activation resulting in vasodilation and bradycardia, thus causing transient hypotension and cerebral hypoperfusion. It is diagnosed through clinical history, cardiac, and esophageal evaluation. We present a case of swallow syncope in a patient with significant cardiac history. Initial cardiac and esophageal testing was normal. Long-term telemetry revealed bradycardia with swallowing, and the patient underwent pacemaker placement. Swallow syncope is associated with a variety of esophageal and cardiac conditions. Management involves addressing the underlying cause; pacemaker placement is sometimes necessary. KEYWORDS: syncope; swallow syncope; reflex syncope; pacemaker.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01588"},"PeriodicalIF":0.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-09eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001590
Mark C Wang, Aileen Bui, Supisara Tintara, Kambiz Etesami, Brian Kim
{"title":"Recurrent Bacteremia and Cholangitis From Eroded Hepatic Artery Pseudoaneurysm Coil Into the Common Hepatic Duct: A Rare Indication for Liver Transplantation.","authors":"Mark C Wang, Aileen Bui, Supisara Tintara, Kambiz Etesami, Brian Kim","doi":"10.14309/crj.0000000000001590","DOIUrl":"10.14309/crj.0000000000001590","url":null,"abstract":"<p><p>Liver transplant may be necessary to manage infectious complications from severe structural biliary disease. In this report, we describe a 71-year-old woman with history of coil-embolized hepatic artery pseudoaneurysm who subsequently developed biliary obstruction resulting from coil erosion into the common hepatic duct. Resultant complications included recurrent cholangitis, bacteremia, and numerous hepatic abscesses. Because of lack of improvement with medical management, the patient underwent liver transplantation and coil removal as the definitive treatment modality. Altogether, this report explores a unique case of liver transplantation as source control for a patient with an active disseminated infection.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01590"},"PeriodicalIF":0.6,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11717500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-09eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001580
Getanshu Malik, Eric Herget, Henry H Nguyen, Mark G Swain
{"title":"Prominent Eustachian Valve Mimicking a Transjugular Intrahepatic Portosystemic Shunt-Associated Thrombosis.","authors":"Getanshu Malik, Eric Herget, Henry H Nguyen, Mark G Swain","doi":"10.14309/crj.0000000000001580","DOIUrl":"10.14309/crj.0000000000001580","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01580"},"PeriodicalIF":0.6,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11717499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-08eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001591
Alexandra Kimchy, Fatima Khambaty, Gustavo Marino
{"title":"Ischemic Jejunitis as a Late Complication of Roux-en-Y Gastric Bypass.","authors":"Alexandra Kimchy, Fatima Khambaty, Gustavo Marino","doi":"10.14309/crj.0000000000001591","DOIUrl":"https://doi.org/10.14309/crj.0000000000001591","url":null,"abstract":"<p><p>The rising prevalence of obesity has led to a substantial investment in the advancement of treatment options for the disease and its comorbid conditions including lifestyle, pharmacologic, and procedural interventions. In this study, we describe a patient with a history of Roux-en-Y gastric bypass who was diagnosed with ischemic jejunitis on upper endoscopy because of the development of an internal hernia, a known late complication of bariatric surgery. This case highlights the diagnostic utility of endoscopy in postgastric bypass complications and the need for safer alternatives to surgery that have the potential to achieve significant weight loss such as bariatric endoscopic therapies.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01591"},"PeriodicalIF":0.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11709216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Esophageal Adenocarcinoma Presenting With Hypercalcemia.","authors":"Rayna Patel, Sahithi Chinnam, Megan Karrick, Abdallah Kobeissy","doi":"10.14309/crj.0000000000001583","DOIUrl":"https://doi.org/10.14309/crj.0000000000001583","url":null,"abstract":"<p><p>Hypercalcemia is an identified complication of several malignancies and can cause significant adverse events. It is usually associated with cancers of the breast, lung (especially squamous cell), renal cell carcinoma, and multiple myeloma. Here, we present a rare case of esophageal adenocarcinoma presenting with hypercalcemia.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01583"},"PeriodicalIF":0.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11709190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-08eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001589
Matt Sumethasorn, Patrick Lee, Neel K Mann, Sarah M Choi, Guang-Qian Xiao, Cynthia Cherfane, Bing Zhang
{"title":"Hemorrhagic Shock Presenting as the First Manifestation of Inflammatory Stricturing Crohn's Disease.","authors":"Matt Sumethasorn, Patrick Lee, Neel K Mann, Sarah M Choi, Guang-Qian Xiao, Cynthia Cherfane, Bing Zhang","doi":"10.14309/crj.0000000000001589","DOIUrl":"https://doi.org/10.14309/crj.0000000000001589","url":null,"abstract":"<p><p>While hematochezia is common in Crohn's disease (CD), severe gastrointestinal hemorrhage causing hemodynamic instability is rare. Strictures, another frequent complication, usually cause obstructive symptoms. We report the first case of hemorrhagic shock from ulcerated ileal strictures as the initial presentation of CD. Standard endoscopy and abdominal imaging did not identify the bleeding source, but capsule endoscopy detected ulcerated strictures confirmed by double-balloon enteroscopy. The patient underwent small bowel resection to reduce rebleeding risk and was started on anti-tumor necrosis factor therapy. This atypical presentation of stricturing CD with hemorrhagic shock underscores the importance of small bowel enteroscopy in guiding clinical decisions.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01589"},"PeriodicalIF":0.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11709149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-12-30eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001570
Harjit Singh, Adam Khalaf, Bryce F Kunkle, Sherry Gholami, James H Lewis, Amol S Rangnekar
{"title":"Atorvastatin-Induced Liver Injury With Concurrent Rhabdomyolysis After a Positive Rechallenge.","authors":"Harjit Singh, Adam Khalaf, Bryce F Kunkle, Sherry Gholami, James H Lewis, Amol S Rangnekar","doi":"10.14309/crj.0000000000001570","DOIUrl":"10.14309/crj.0000000000001570","url":null,"abstract":"<p><p>Statin-induced liver injury has been widely described. However, cases of clinically significant liver injury are rare. We present a 56-year-old woman who developed atorvastatin-induced grade III acute liver injury with concurrent rhabdomyolysis that worsened after rechallenging, which highlighted the need for pharmacovigilance with statins. The Roussel Uclaf Causality Assessment Method and Revised Electronic Causality Assessment Method both showed that atorvastatin was highly probable in causing hepatotoxicity. To our knowledge, this is the first reported case of concurrent drug-induced liver injury and rhabdomyolysis after a positive rechallenge with atorvastatin.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01570"},"PeriodicalIF":0.6,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11688008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Severe Diffuse Ulcerative Esophagitis Caused by Epstein-Barr Virus/Cytomegalovirus Coinfection in an Immunocompetent Individual.","authors":"Kartikeya Mathur, Chhagan Lal Birda, Satyam Kumar Singh, Vvienodd Uppuv, Shubham Kashyap, Ashish Agarwal","doi":"10.14309/crj.0000000000001578","DOIUrl":"10.14309/crj.0000000000001578","url":null,"abstract":"<p><p>Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are important causes of viral esophagitis mainly in immunocompromised individuals. Both viruses lead to development of focal ulcerations in the esophagus. While there have been rare case reports of esophagitis in immunocompetent individuals, there has not been a single reported case of coinfection with both CMV and EBV in an immunocompetent individual and presenting with diffuse esophageal ulceration. We report a case of severe diffuse ulcerative esophagitis caused by EBV/CMV coinfection in an immunocompetent individual.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01578"},"PeriodicalIF":0.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}