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A Rare Presentation of a Devastating Disease: Hepatosplenic T-Cell Lymphoma in Crohn's Disease Without Thiopurine Exposure. 一种罕见的毁灭性疾病的表现：没有硫嘌呤暴露的克罗恩病肝脾t细胞淋巴瘤。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-08 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001695
Michael Chang, Michael Frohlinger, Nathan Williams, Lauren George
{"title":"A Rare Presentation of a Devastating Disease: Hepatosplenic T-Cell Lymphoma in Crohn's Disease Without Thiopurine Exposure.","authors":"Michael Chang, Michael Frohlinger, Nathan Williams, Lauren George","doi":"10.14309/crj.0000000000001695","DOIUrl":"https://doi.org/10.14309/crj.0000000000001695","url":null,"abstract":"<p><p>Hepatosplenic T-cell lymphoma (HSTCL) is a rare, aggressive malignancy that has been associated with thiopurines during the treatment of inflammatory bowel disease (IBD). We present a case of a 26-year-old man with Crohn's disease on infliximab without prior thiopurine exposure who developed HSTCL. His diagnosis was confirmed through flow cytometry, fluorescence in situ hybridization, and bone marrow biopsy. This is the sixth case of HSTCL in patients with IBD without prior thiopurine exposure and highlights the need for a comprehensive risk-benefit discussion with patients on the various treatment modalities for IBD.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01695"},"PeriodicalIF":0.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12061462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unusual Cause of Acute Pancreatitis. 急性胰腺炎的不寻常原因。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-08 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001694
Adel Hajj Ali, Natashay J Bailey, Hala Fatima, James L Watkins, Nasir Saleem
{"title":"An Unusual Cause of Acute Pancreatitis.","authors":"Adel Hajj Ali, Natashay J Bailey, Hala Fatima, James L Watkins, Nasir Saleem","doi":"10.14309/crj.0000000000001694","DOIUrl":"https://doi.org/10.14309/crj.0000000000001694","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01694"},"PeriodicalIF":0.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12061459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microangiopathic Hemolytic Anemia Following Transjugular Intrahepatic Portosystemic Shunt Creation in an Adolescent. 青少年经颈静脉肝内门静脉系统分流术后的微血管病溶血性贫血。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-07 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001685
Jing Y Khoo, Mark L Lessne, Vani V Gopalareddy
{"title":"Microangiopathic Hemolytic Anemia Following Transjugular Intrahepatic Portosystemic Shunt Creation in an Adolescent.","authors":"Jing Y Khoo, Mark L Lessne, Vani V Gopalareddy","doi":"10.14309/crj.0000000000001685","DOIUrl":"https://doi.org/10.14309/crj.0000000000001685","url":null,"abstract":"<p><p>Transjugular intrahepatic portosystemic shunt (TIPS) creation is an effective approach to address the complications of portal hypertension. This case report describes an adolescent boy who underwent TIPS creation with an expanded polytetrafluorethylene-lined stent graft for portal hypertension secondary to sinusoidal obstruction syndrome. He subsequently developed microangiopathic hemolytic anemia, an uncommon complication of covered stents that is not well reported in the pediatric population. Despite its rarity and typical conservative management, microangiopathic hemolytic anemia should be considered and regularly monitored in the months following TIPS creation in pediatric patients.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01685"},"PeriodicalIF":0.6,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Swallowed by the Past: Dysphagia as a Decade-Late Manifestation of Renal Cell Carcinoma Recurrence. 被过去吞噬：吞咽困难是肾细胞癌复发的十年晚期表现。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-05 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001693
Hassam Ali, Fnu Poonam, Prashant Mudireddy
{"title":"Swallowed by the Past: Dysphagia as a Decade-Late Manifestation of Renal Cell Carcinoma Recurrence.","authors":"Hassam Ali, Fnu Poonam, Prashant Mudireddy","doi":"10.14309/crj.0000000000001693","DOIUrl":"https://doi.org/10.14309/crj.0000000000001693","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01693"},"PeriodicalIF":0.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Curious Case of Walking Cholangitis in a Nonendemic Region: Hepatobiliary Fascioliasis. 非地方性胆管炎的一例奇怪病例：肝胆片吸虫病。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-05 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001700
Anupam Kumar Singh, Jahnvi Dhar, Saroj Kant Sinha, Jayanta Samanta
{"title":"A Curious Case of Walking Cholangitis in a Nonendemic Region: Hepatobiliary Fascioliasis.","authors":"Anupam Kumar Singh, Jahnvi Dhar, Saroj Kant Sinha, Jayanta Samanta","doi":"10.14309/crj.0000000000001700","DOIUrl":"https://doi.org/10.14309/crj.0000000000001700","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01700"},"PeriodicalIF":0.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Esophageal Epidermoid Metaplasia Treated With Endoscopic Submucosal Dissection. 内镜下粘膜剥离治疗食管表皮样化生。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-05 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001698
Karam Al-Bayati, Gerard Coneys, Michael Cantor, Rodica Gheorghe, James K Stone
{"title":"Esophageal Epidermoid Metaplasia Treated With Endoscopic Submucosal Dissection.","authors":"Karam Al-Bayati, Gerard Coneys, Michael Cantor, Rodica Gheorghe, James K Stone","doi":"10.14309/crj.0000000000001698","DOIUrl":"https://doi.org/10.14309/crj.0000000000001698","url":null,"abstract":"<p><p>Esophageal epidermoid metaplasia (EEM) is a rare condition characterized by well-demarcated leukoplakia affecting the middle-to-distal esophagus. EEM commonly presents in middle-aged females with dysphagia and gastroesophageal reflux. EEM is thought to be associated with high-grade squamous dysplasia and squamous cell carcinoma. We report a case of a 63-year-old woman diagnosed with EEM after en bloc endoscopic submucosal dissection in a lesion initially reported as squamous dysplasia. The patient was initiated on a PPI with a 6-month follow-up showing no areas of squamous dysplasia or recurrent EEM with normal squamous mucosa on biopsy. The patient was symptom-free at 1-year follow-up.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01698"},"PeriodicalIF":0.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Double Trouble: Leishmaniasis and Cytomegalovirus Colitis in an Immunocompromised Host. 双重麻烦：免疫功能低下宿主的利什曼病和巨细胞病毒结肠炎。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-05 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001687
Saleh Alghaythi, Aymen Almuhaidb, Badr Al-Bawardy
{"title":"Double Trouble: Leishmaniasis and Cytomegalovirus Colitis in an Immunocompromised Host.","authors":"Saleh Alghaythi, Aymen Almuhaidb, Badr Al-Bawardy","doi":"10.14309/crj.0000000000001687","DOIUrl":"https://doi.org/10.14309/crj.0000000000001687","url":null,"abstract":"<p><p>Leishmaniasis is endemic in several areas of the world. It is a chronic protozoan disease transmitted through the bite of the Phlebotomus fly. Unusual localizations of visceral leishmaniasis are extremely rare and are described in immunocompromised patients. We present a case of a 73-year-old man, postliving nonrelated kidney transplant who complained of melena, fatigue, and weight loss. Gastroscopy showed a large ulcer at the lesser curvature of the stomach, and biopsies demonstrated severe ulceration with superimposed fungal organisms. Colonoscopy showed a polyp in the transverse colon, and histopathological examination revealed cytomegalovirus colitis with superimposed leishmaniasis.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01687"},"PeriodicalIF":0.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Subepithelial Lesion in the Colon Masquerading as Metastatic Prostate Cancer. 结肠癌上皮下病变伪装成转移性前列腺癌。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-05 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001689
Rahil H Shah, Michael D Brophey, Megan Wachsmann, Bradford Barker, Shawn L Shah
{"title":"A Subepithelial Lesion in the Colon Masquerading as Metastatic Prostate Cancer.","authors":"Rahil H Shah, Michael D Brophey, Megan Wachsmann, Bradford Barker, Shawn L Shah","doi":"10.14309/crj.0000000000001689","DOIUrl":"10.14309/crj.0000000000001689","url":null,"abstract":"<p><p>Although the colon is a known site for tumor metastasis, it is relatively uncommon. In particular, prostate cancer may spread to the colon via locoregional penetration in locally advanced tumors. This can be easily seen on flexible sigmoidoscopy as an infiltrative lesion. However, a tumor deposit from prostate cancer presenting as a subepithelial lesion within the colon has never previously been reported. Here, we present a case of a patient with known prostate cancer who was found to have sigmoid colon uptake off imaging that demonstrated metastatic prostate cancer after endoscopic ultrasound-guided fine-needle biopsy of the subepithelial lesion.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01689"},"PeriodicalIF":0.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric Pancreatic Panniculitis: An Uncommon Manifestation of Acute Pancreatitis. 小儿胰膜炎：急性胰腺炎的一种罕见表现。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-02 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001696
Ajay Aravind, Bhoomika Ishran, Ujjal Poddar, Ram Nawal Rao, Anshu Srivastava, Moinak Sen Sarma
{"title":"Pediatric Pancreatic Panniculitis: An Uncommon Manifestation of Acute Pancreatitis.","authors":"Ajay Aravind, Bhoomika Ishran, Ujjal Poddar, Ram Nawal Rao, Anshu Srivastava, Moinak Sen Sarma","doi":"10.14309/crj.0000000000001696","DOIUrl":"https://doi.org/10.14309/crj.0000000000001696","url":null,"abstract":"<p><p>Pancreatic panniculitis is an inflammation of subcutaneous adipose tissue associated with acute or chronic pancreatic diseases. Two-year-old girl presented with pain abdomen, fever, and multiple tender erythematous nodules over legs, abdomen and back for 1 week. Computed tomography scan suggestive of acute necrotizing pancreatitis. Skin biopsy revealed typical features of septal panniculitis. The child improved with supportive treatment with regression of skin nodules. Although rare, physicians must be aware of this condition closely mimicking vasculitis to avoid delay in diagnosis.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01696"},"PeriodicalIF":0.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12047867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytomegalovirus-Induced Colitis Presenting as Acute Appendicitis in an Immunocompetent Patient With Ulcerative Colitis. 免疫功能正常的溃疡性结肠炎患者巨细胞病毒诱导结肠炎表现为急性阑尾炎。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-02 eCollection Date: 2025-05-01 DOI: 10.14309/crj.0000000000001682
Alessandro Pedicelli, Amine Zoughlami, Olga Aleynikova, Christina Greenaway, Corey Miller
{"title":"Cytomegalovirus-Induced Colitis Presenting as Acute Appendicitis in an Immunocompetent Patient With Ulcerative Colitis.","authors":"Alessandro Pedicelli, Amine Zoughlami, Olga Aleynikova, Christina Greenaway, Corey Miller","doi":"10.14309/crj.0000000000001682","DOIUrl":"https://doi.org/10.14309/crj.0000000000001682","url":null,"abstract":"<p><p>We report a rare case of cytomegalovirus (CMV) colitis presenting radiologically as acute appendicitis in an immunocompetent 71-year-old man known for ulcerative colitis. Although initial imaging revealed acute appendicitis, a lack of clinical improvement with antibiotic therapy prompted further evaluation with colonoscopy, which led to the diagnosis of CMV colitis on a background of mild ulcerative colitis flare. Most individuals infected by CMV will exhibit lifelong latency; however, the virus can reactivate under impaired immune status (eg, transplant recipients, those receiving immunosuppressive therapy). Patients with underlying inflammatory bowel disease are especially at risk of CMV colitis during an acute flare. This case illustrates a unique presentation of CMV colitis in an immunocompetent host, with initial imaging studies revealing acute appendicitis.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 5","pages":"e01682"},"PeriodicalIF":0.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12047887/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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