ACG Case Reports JournalPub Date : 2024-08-30eCollection Date: 2024-09-01DOI: 10.14309/crj.0000000000001455
Frank Lin, Ayah Obeid, Harsh Bhalala, Nishit Patel, Li Ge, Ronak Modi
{"title":"Behcet's Disease Presenting as Pancolonic Ulcerations in a Patient With Kikuchi-Fujimoto Disease: A Rare Gastrointestinal Manifestation.","authors":"Frank Lin, Ayah Obeid, Harsh Bhalala, Nishit Patel, Li Ge, Ronak Modi","doi":"10.14309/crj.0000000000001455","DOIUrl":"10.14309/crj.0000000000001455","url":null,"abstract":"<p><p>Kikuchi-Fujimoto disease (KFD) is a rare and self-limiting disorder characterized by cervical lymphadenopathy and fever. In this report, we present a case of a 24-year-old man with known history of KFD who presented with lower gastrointestinal bleeding and acute blood loss anemia. Further evaluation with colonoscopy showed widespread ulcerations in the colon and terminal ileum with suspicion for Behcet's disease. Biopsy from the colonic mucosa and ileocecal valve demonstrated focal ulcer with cryptitis and lymphoid aggregates that can be seen in Behcet's syndrome; however, it lacks specificity and Behcet's disease is a clinical diagnosis. This case emphasizes the importance of including gastrointestinal bleeding as a potential manifestation due to Behcet's disease in patients diagnosed with KFD.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01455"},"PeriodicalIF":0.6,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11365614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-08-29eCollection Date: 2024-09-01DOI: 10.14309/crj.0000000000001488
Prince A Ameyaw, David Parsons, Ali Mahmoud, Robert Marie, Anil Nagar, Harry R Aslanian
{"title":"Coexistent Eosinophilic Esophagitis and Dysplastic Barrett's Esophagus With Rapid Eosinophilic Infiltration of Neosquamous Mucosa After Radiofrequency Ablation.","authors":"Prince A Ameyaw, David Parsons, Ali Mahmoud, Robert Marie, Anil Nagar, Harry R Aslanian","doi":"10.14309/crj.0000000000001488","DOIUrl":"10.14309/crj.0000000000001488","url":null,"abstract":"<p><p>The coexistence of eosinophilic esophagitis (EoE) and Barrett's esophagus (BE) is rare despite the known association of gastroesophageal reflux disease with both conditions. Radiofrequency ablation is an effective endoscopic eradication therapy in patients with dysplastic BE. However, the efficacy and outcomes of radiofrequency ablation in patients with concomitant EoE and BE are not well known. We report a case of rapid eosinophilic infiltration of the neosquamous mucosa after the complete eradication of long-segment dysplastic BE in a patient with coexisting BE and EoE.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01488"},"PeriodicalIF":0.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11361630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-08-29eCollection Date: 2024-09-01DOI: 10.14309/crj.0000000000001464
Mary McGrath, Calvin Geng, Anthony Rainho, Esteban Figueroa
{"title":"Aseptic Splenic Abscesses With Concomitant Sweet Syndrome as Extraintestinal Manifestations of New-Onset Crohn's Disease.","authors":"Mary McGrath, Calvin Geng, Anthony Rainho, Esteban Figueroa","doi":"10.14309/crj.0000000000001464","DOIUrl":"10.14309/crj.0000000000001464","url":null,"abstract":"<p><p>Splenic abscesses are typically infectious in nature but have rarely been reported as an extraintestinal manifestation of inflammatory bowel disease, particularly of Crohn's disease. In the United States, reported cases are even more scarce. We present a case of aseptic splenic abscess with concomitant Sweet syndrome in a middle-aged woman with newly diagnosed Crohn's disease. Extensive workup was required to reach final diagnosis, and she rapidly improved with corticosteroid therapy and has been maintained on risankizumab. We aim to contribute to limited data and heighten clinician awareness of these atypical extraintestinal manifestations.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01464"},"PeriodicalIF":0.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11361625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-08-29eCollection Date: 2024-09-01DOI: 10.14309/crj.0000000000001478
Rangesh Modi, Gloria Erazo, Reddy Anand
{"title":"Villous Adenoma: A Rare Cause of Neural Epidermal Growth Factor-Like 1-Positive Membranous Nephropathy.","authors":"Rangesh Modi, Gloria Erazo, Reddy Anand","doi":"10.14309/crj.0000000000001478","DOIUrl":"10.14309/crj.0000000000001478","url":null,"abstract":"<p><p>We report the case of a 70-year-old woman diagnosed with neural epidermal growth factor-like 1 antigen-positive membranous nephropathy and nephrotic syndrome. Following thorough exclusion of autoimmune diseases, medications, or infections as potential causes, colonoscopy was performed as part of malignancy evaluation, revealing an 18 mm villous adenoma in the sigmoid colon and a 7 mm tubulovillous adenoma in the cecum. Despite the absence of gastrointestinal symptoms initially and the absence of high-grade dysplasia in the pathology report, the patient experienced a remarkable improvement in symptoms and a reduction in nephrotic-range proteinuria following polypectomy, observed within a few months.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01478"},"PeriodicalIF":0.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11361626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-08-29eCollection Date: 2024-09-01DOI: 10.14309/crj.0000000000001468
Lotus Alphonsus, Qi Zhang, Vipul Jairath
{"title":"Multifocal Epstein-Barr Virus-Positive Mucocutaneous Ulcers in a Patient With Crohn's Disease.","authors":"Lotus Alphonsus, Qi Zhang, Vipul Jairath","doi":"10.14309/crj.0000000000001468","DOIUrl":"10.14309/crj.0000000000001468","url":null,"abstract":"<p><p>Epstein-Barr Virus-positive mucocutaneous ulcer (EBVMCU) is a rare and new category of mature B-cell neoplasms commonly linked to immunosuppression. It often has a benign course and regresses spontaneously after discontinuation or dose reduction of immunosuppressive agents. We report the case of a 48-year-old woman on long-term azathioprine therapy for rectosigmoid Crohn's disease. In contrast to the prevalent sites typically associated with EBVMCU, such as the oral mucosa and skin, this patient was found to have locations in the gastrointestinal tract and upper neck. These areas tested positive for histopathology consistent with EBVMCU and were excised due to bowel perforation and concern for malignancy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01468"},"PeriodicalIF":0.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11361628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-08-29eCollection Date: 2024-09-01DOI: 10.14309/crj.0000000000001479
Jesús M Luévano, Chip Bowman, Reuben Garcia-Carrasquillo
{"title":"Appendiceal Elastofibroma Requiring Ileocecectomy.","authors":"Jesús M Luévano, Chip Bowman, Reuben Garcia-Carrasquillo","doi":"10.14309/crj.0000000000001479","DOIUrl":"10.14309/crj.0000000000001479","url":null,"abstract":"<p><p>Elastrofibromas are rare lesions characterized by collagen and elastic fiber deposition. They are generally found in soft tissues and throughout the gastrointestinal tract. The pathogenesis of this lesion is still uncertain, but it is hypothesized to be a reactive process. We present a case of an appendiceal elastofibroma, a unique anatomic location that necessitated surgical removal, with pathologic findings suggestive of an inciting event from a sclerosed vascular abnormality.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01479"},"PeriodicalIF":0.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11361629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-08-29eCollection Date: 2024-09-01DOI: 10.14309/crj.0000000000001476
Nan Lan, Bo Shen
{"title":"Efficacy and Safety of Risankizumab in the Treatment of Crohn's Disease of the Pouch.","authors":"Nan Lan, Bo Shen","doi":"10.14309/crj.0000000000001476","DOIUrl":"10.14309/crj.0000000000001476","url":null,"abstract":"<p><p>Risankizumab has shown efficacy in the treatment of moderate-to-severe Crohn's disease (CD). The use of risankizumab in the treatment of CD of the pouch has not been previously reported. Here, we have 10 patients with biologics exposed CD of the pouch treated with risankizumab. Some patients showed endoscopic improvement regarding inflammation with minimal clinical improvement. Our findings warrant further study to validate the efficacy and safety of risankizumab in the treatment of CD of the pouch.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01476"},"PeriodicalIF":0.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11361627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-08-29eCollection Date: 2024-09-01DOI: 10.14309/crj.0000000000001485
Yudai Koya, Koki Yamaguchi, Shinji Mukawa, Koichiro Miyagawa
{"title":"Migration of a Duodenoscope to the Esophagus Which Was Successfully Retrieved Using a Recovery Method: A Rare Complication of Endoscopic Retrograde Cholangiopancreatography.","authors":"Yudai Koya, Koki Yamaguchi, Shinji Mukawa, Koichiro Miyagawa","doi":"10.14309/crj.0000000000001485","DOIUrl":"10.14309/crj.0000000000001485","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01485"},"PeriodicalIF":0.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11361624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-08-26eCollection Date: 2024-08-01DOI: 10.14309/crj.0000000000001472
Rishi Bolla, Carolina Martinez, David Metter, Jonathan Hilal
{"title":"Postpolypectomy Bleeding Gone Wrong: Primary Colonic Epithelioid Angiosarcoma.","authors":"Rishi Bolla, Carolina Martinez, David Metter, Jonathan Hilal","doi":"10.14309/crj.0000000000001472","DOIUrl":"https://doi.org/10.14309/crj.0000000000001472","url":null,"abstract":"<p><p>Epithelioid angiosarcoma is an aggressive form of angiosarcoma, and primary colonic tumors are extremely rare. We present the case of a 60-year-old man who presented with what initially appeared to be postpolypectomy bleeding. After undergoing repeat endoscopy, he was found to have epithelioid angiosarcoma of the transverse colon, and imaging further confirmed that it was the primary tumor site. Our patient underwent segmental resection of his transverse colon. The patient's initial presentation as postpolypectomy bleeding and his continued cancer-free survival after a relatively limited surgery are unique features not previously seen.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 8","pages":"e01472"},"PeriodicalIF":0.6,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11350336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-08-26eCollection Date: 2024-08-01DOI: 10.14309/crj.0000000000001461
Kassidy Veasaw, Elona Poltiyelova, Zilan Lin, Anila Kumar, Shireen Pais
{"title":"Varices at Choledochojejunostomy Site as the Elusive Gastrointestinal Bleeding Source in a Post-Whipple Patient.","authors":"Kassidy Veasaw, Elona Poltiyelova, Zilan Lin, Anila Kumar, Shireen Pais","doi":"10.14309/crj.0000000000001461","DOIUrl":"https://doi.org/10.14309/crj.0000000000001461","url":null,"abstract":"<p><p>Ectopic varices are portosystemic collaterals that form outside the esophagogastric region. If left untreated, they can carry a high mortality rate. Although ectopic variceal bleeding occurs rarely, it continues to pose both diagnostic and therapeutic challenges and remains an under-recognized source of gastrointestinal (GI) hemorrhage. We present a case of GI bleeding from varices formed at the choledochojejunosomy site in a post-Whipple patient. This case describes the rare finding of ectopic varices after pancreaticoduodenectomy, emphasizes the challenges in diagnosis and treatment, and highlights the need for a multidisciplinary approach managing GI bleeding in this patient population.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 8","pages":"e01461"},"PeriodicalIF":0.6,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11350320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}