ACG Case Reports JournalPub Date : 2024-12-27eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001579
Andrew M Turunen, Reilly A Coombs, Sushil Kumar Garg
{"title":"Semaglutide-Associated Gastric Pneumatosis.","authors":"Andrew M Turunen, Reilly A Coombs, Sushil Kumar Garg","doi":"10.14309/crj.0000000000001579","DOIUrl":"10.14309/crj.0000000000001579","url":null,"abstract":"<p><p>Semaglutide, a glucagon-like peptide-1 receptor agonist, used for Type 2 diabetes mellitus and more recently for weight loss, often causes gastrointestinal adverse effects such as delayed gastric emptying and abdominal discomfort. Current literature has not described an associated case of gastric pneumatosis with semaglutide use. We report a 61-year-old man on semaglutide for 9 months with gastric pneumatosis. Symptoms resolved on discontinuation. Clinicians should be vigilant for significant gastrointestinal adverse effects, including pneumatosis with semaglutide use.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01579"},"PeriodicalIF":0.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-12-27eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001577
Andrea Gomez Pons, Frank J Lukens, Osayande Osagiede
{"title":"Small-Bowel Metastatic Melanoma From Primary Mucosal Melanoma of the Anus: A Comprehensive Case Report.","authors":"Andrea Gomez Pons, Frank J Lukens, Osayande Osagiede","doi":"10.14309/crj.0000000000001577","DOIUrl":"10.14309/crj.0000000000001577","url":null,"abstract":"<p><p>Anorectal mucosal melanoma (ARMM) is exceptionally rare, highly malignant, and characterized by a poor prognosis. We present the case of a 76-year-old woman with ARMM and recurrent gastrointestinal (GI) bleeding/anemia caused by small-bowel metastases, which was successfully managed with laparoscopic resection. ARMM is an aggressive type of cancer that has the potential to metastasize to the GI tract approximately 4.5 years after the primary diagnosis. Intussusception and GI bleed are potential complications. Small-bowel metastatic melanoma typically goes undiagnosed until autopsy and requires a multidisciplinary approach. Key treatment options include surgery and immunotherapy to improve patient outcomes.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01577"},"PeriodicalIF":0.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-12-27eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001575
William K B Boateng, Neil Carlin, Etan Spira, Maria E Szabela, Kosisochukwu J Ezeh
{"title":"Acute Hepatitis B Infection in a Patient With Confirmed Immunity on Long-Acting Cabotegravir/Rilpivirine.","authors":"William K B Boateng, Neil Carlin, Etan Spira, Maria E Szabela, Kosisochukwu J Ezeh","doi":"10.14309/crj.0000000000001575","DOIUrl":"10.14309/crj.0000000000001575","url":null,"abstract":"<p><p>Long-acting injectable formulation of cabotegravir/rilpivirine (CAB/RPV) is a promising novel maintenance therapy for HIV infection. However, coinfection with active hepatitis B virus (HBV) infection is a contraindication to initiating this therapy. Despite guidelines, patients with HBV immunity can still contract acute HBV infection. We report a case of a 30-year-old man with HIV who transitioned from antiretroviral therapy to CAB/RPV and had confirmed HBV immunity. The patient, though asymptomatic, showed significantly elevated liver function tests (LFTs) before his monthly CAB/RPV injection. He was hospitalized and diagnosed with acute HBV infection. His LFTs improved, and he was taken off CAB/RPV and returned to antiretroviral therapy for the treatment of HIV and HBV. During subsequent follow-ups as an outpatient, the patient's LFTs normalized, and his HBV viral load significantly decreased. This case highlights the potential need for routine HBV testing in patients on CAB/RPV therapy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01575"},"PeriodicalIF":0.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-12-27eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001569
Misha Gautam, Vinay Jahagirdar, Himil Mahadevia, Kimberly Sanders, John P Campbell, Pamela B Sylvestre, Rajiv Chhabra, Wendell Clarkston, Sreenivasa S Jonnalagadda
{"title":"Double Whammy: A Case Report of Immune Checkpoint Inhibitor Colitis and Concomitant <i>Cytomegalovirus</i> Colitis in a Patient on Nivolumab.","authors":"Misha Gautam, Vinay Jahagirdar, Himil Mahadevia, Kimberly Sanders, John P Campbell, Pamela B Sylvestre, Rajiv Chhabra, Wendell Clarkston, Sreenivasa S Jonnalagadda","doi":"10.14309/crj.0000000000001569","DOIUrl":"10.14309/crj.0000000000001569","url":null,"abstract":"<p><p>Immune checkpoint inhibitors commonly cause gastrointestinal immune-related adverse effects. These patients also carry an increased risk of concomitant infections. This 66-year-old man with immune checkpoint inhibitor colitis was discovered to have concurrent <i>Yersinia</i> and <i>Cytomegalovirus</i> colitis. Such infections may mimic or complicate disease course. Hence, clinicians must monitor patient symptoms, have a low threshold for infectious testing and colonoscopy, and consider treatment strategies to mitigate their risk.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01569"},"PeriodicalIF":0.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Bile Ducts to Esophagus: A Novel Cholangioscopic Method for Foreign Body Removal.","authors":"Akshaya Sathyamurthy Iyer, Vikramaditya Rawat, Saiprasad Lad, Mit Shah, Motij Kumar Dalai, Meghraj Ingle","doi":"10.14309/crj.0000000000001561","DOIUrl":"10.14309/crj.0000000000001561","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01561"},"PeriodicalIF":0.6,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-12-20eCollection Date: 2024-12-01DOI: 10.14309/crj.0000000000001571
Himsikhar Khataniar, Aakash Desai, Gursimran S Kochhar
{"title":"Initial Experience With Safety and Efficacy of Endoscopic Full-Thickness Resection in Patients With Inflammatory Bowel Disease: A Case Series.","authors":"Himsikhar Khataniar, Aakash Desai, Gursimran S Kochhar","doi":"10.14309/crj.0000000000001571","DOIUrl":"10.14309/crj.0000000000001571","url":null,"abstract":"<p><p>Endoscopic full-thickness resection (EFTR) is a novel endoscopic technique for removing complex colorectal lesions. The inflammatory bowel disease (IBD) population poses unique challenges for endoscopic resection due to an increased prevalence of fibrotic, nonlifting lesions and higher recurrence rates compared with the general population. This case series reports on the successful use of EFTR in 5 patients with IBD who had challenging colonic polyps, including fibrotic and nonlifting lesions. Technical success was achieved in all cases without any postoperative complications. Follow-up surveillance revealed no residual lesions or recurrence, and histopathological analysis confirmed full-thickness resection in all samples. This is one of the first case series suggesting that EFTR is a promising, safe, and effective alternative to surgery for managing complex colorectal polyps in patients with IBD.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 12","pages":"e01571"},"PeriodicalIF":0.6,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11661704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-12-20eCollection Date: 2024-12-01DOI: 10.14309/crj.0000000000001574
Nihal Ijaz Khan, Abdullah Abbasi, Saurabh Chandan, Sagar Pathak, Charanjeet Singh, Muhammad K Hasan
{"title":"A Case of Transduodenal Endoscopic Ultrasound-Guided Biopsy of an Appendiceal Lesion.","authors":"Nihal Ijaz Khan, Abdullah Abbasi, Saurabh Chandan, Sagar Pathak, Charanjeet Singh, Muhammad K Hasan","doi":"10.14309/crj.0000000000001574","DOIUrl":"10.14309/crj.0000000000001574","url":null,"abstract":"<p><p>Vermiform appendiceal cancers are rare and commonly diagnosed incidentally after appendectomy for acute appendicitis. Establishing a diagnosis and staging appendiceal cancer is important as the treatment options differ based on the subtypes of tumor and their spread in the peritoneum. The role of endosonography in tissue diagnosis of appendiceal cancer is limited. Most cases are diagnosed and staged radiologically and surgically. Tissue diagnosis is key in management, especially when diagnosis is unclear by other modalities. We report a case of transduodenal endoscopic ultrasound-guided biopsy of an appendiceal lesion, which had significant impact on patient outcome.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 12","pages":"e01574"},"PeriodicalIF":0.6,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11661737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2024-12-20eCollection Date: 2024-12-01DOI: 10.14309/crj.0000000000001573
Karam Karam, Elias Fiani, Ihab I El Hajj
{"title":"Inadvertent Wire Shearing During Endoscopic Ultrasound-Guided Rendezvous Procedure.","authors":"Karam Karam, Elias Fiani, Ihab I El Hajj","doi":"10.14309/crj.0000000000001573","DOIUrl":"10.14309/crj.0000000000001573","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 12","pages":"e01573"},"PeriodicalIF":0.6,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11661733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}