ACG Case Reports JournalPub Date : 2026-08-10eCollection Date: 2026-08-01DOI: 10.14309/crj.0000000000002260
Wesley Dixon, Brittany Bromfield, Mark Redston, Jordan Sack
{"title":"Kwashiorkor Mimicking Portal Hypertensive Ascites After Bariatric Surgery.","authors":"Wesley Dixon, Brittany Bromfield, Mark Redston, Jordan Sack","doi":"10.14309/crj.0000000000002260","DOIUrl":"10.14309/crj.0000000000002260","url":null,"abstract":"<p><p>Kwashiorkor is a severe form of protein-calorie malnutrition. It is rarely observed in well-developed countries and is a potential complication of bariatric surgery. We report a case of kwashiorkor presenting as new-onset hepatic steatosis and high serum-ascites albumin gradient, low total protein ascites in an adult 2 years after Roux-en-Y gastric bypass with heavy alcohol use, and pancreatic insufficiency. The ascites resolved with parenteral nutrition, alcohol cessation, and pancreatic enzyme supplementation. This case highlights the diagnostic and pathophysiologic complexity of malnutrition-related liver disease in the bariatric population, especially considering that it can mimic the more commonly encountered portal hypertensive ascites.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 8","pages":"e02260"},"PeriodicalIF":0.6,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13456838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2026-08-10eCollection Date: 2026-08-01DOI: 10.14309/crj.0000000000002258
Ali Ghanem Al Masad, Mahdi Abdulhadi Al Muammar, Omar Reda Abdelmaksoud
{"title":"Severe Chronic Anemia and Tumor-Mimicking Colonic Lesions as an Atypical Presentation of Crohn's Colitis.","authors":"Ali Ghanem Al Masad, Mahdi Abdulhadi Al Muammar, Omar Reda Abdelmaksoud","doi":"10.14309/crj.0000000000002258","DOIUrl":"10.14309/crj.0000000000002258","url":null,"abstract":"<p><p>Crohn's colitis may rarely present with severe bleeding and tumor-mimicking colonic lesions, creating concern for malignancy. A 20-year-old bedridden man with cerebral palsy had recurrent hematochezia and transfusion-dependent microcytic anemia, with hemoglobin 2.8 g/dL. Colonoscopy showed diffuse raised island-like plaques with vascular-pattern loss, rectal sparing, edematous ileocecal valve, and an oozing transverse-colon lesion requiring clipping. Multisite biopsies showed chronic active colitis with crypt distortion, cryptitis, and crypt abscesses, without granulomas, dysplasia, or malignancy. Tissue tuberculosis polymerase chain reaction was negative; interferon-gamma release assay was unavailable. Crohn's colitis was favored by clinicopathologic correlation. Bleeding resolved after corticosteroids, infliximab, and azathioprine; hemoglobin improved to 9.9 g/dL.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 8","pages":"e02258"},"PeriodicalIF":0.6,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13456836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2026-08-03eCollection Date: 2026-08-01DOI: 10.14309/crj.0000000000002261
Anil Mathew Philip, Daryl Forney, Lina James George, Saksham Kohli, Victoria Alagiozian-Angelova, Anas Almoghrabi
{"title":"Multifocal Giant Granular Cell Tumors of the Alimentary Canal With Concurrent Eosinophilic Gastrointestinal Disease.","authors":"Anil Mathew Philip, Daryl Forney, Lina James George, Saksham Kohli, Victoria Alagiozian-Angelova, Anas Almoghrabi","doi":"10.14309/crj.0000000000002261","DOIUrl":"10.14309/crj.0000000000002261","url":null,"abstract":"<p><p>Granular cell tumors (GCTs) are rare, typically benign Schwann cell neoplasms; within the gastrointestinal (GI) tract, the esophagus is the most frequent site. Eosinophilic gastrointestinal diseases are chronic immune-mediated conditions encompassing eosinophilic esophagitis, gastroenteritis, and colitis. We describe a 49-year-old man with prior testicular seminoma, follicular thyroid carcinoma, and cutaneous GCTs who developed multifocal esophageal and rectal GCTs alongside eosinophilic esophagitis, esophagitis gastroenteritis, and esophagitis colitis, plus an incidental sigmoid neuroendocrine tumor (WHO grade 2). To our knowledge, this is the first reported case of concurrent multisegmental eosinophilic gastrointestinal diseases, multifocal GCTs, and a neuroendocrine tumors (NET), highlighting the need for vigilant endoscopic surveillance.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 8","pages":"e02261"},"PeriodicalIF":0.6,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13433105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148668297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2026-07-23eCollection Date: 2026-07-01DOI: 10.14309/crj.0000000000002254
Trent Walradt, Michael J Senter-Zapata, Jonah Cohen
{"title":"Barium Where It Does Not Belong: Retrograde Filling of the Biliary Tree.","authors":"Trent Walradt, Michael J Senter-Zapata, Jonah Cohen","doi":"10.14309/crj.0000000000002254","DOIUrl":"10.14309/crj.0000000000002254","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 7","pages":"e02254"},"PeriodicalIF":0.6,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13395485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148576760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2026-07-23eCollection Date: 2026-07-01DOI: 10.14309/crj.0000000000002248
Adam Swanson, Jacob S Schwarz, Aeryana N Bektas, Jia Liu
{"title":"Use of Prucalopride in Severe Ileus in a Critically Ill Patient With Acute Alcoholic Hepatitis and Hepatic Encephalopathy.","authors":"Adam Swanson, Jacob S Schwarz, Aeryana N Bektas, Jia Liu","doi":"10.14309/crj.0000000000002248","DOIUrl":"10.14309/crj.0000000000002248","url":null,"abstract":"<p><p>Ileus is a common gastrointestinal complication in critically ill patients, posing a unique management challenge due to its multifactorial etiology and impact on clinical stability. Standard therapeutic approaches often fail in the setting of metabolic derangement and hemodynamic instability. Prucalopride, a selective 5-HT<sub>4</sub> receptor agonist, has demonstrated efficacy in promoting colonic motility; however, its use in severe small bowel and colonic ileus or decompensated liver disease populations remains limited. We report the case of a 28-year-old man with decompensated alcoholic hepatitis who developed severe small bowel and colonic ileus refractory to standard management. Concerns for worsening illness prompted a trial of prucalopride, which was temporally associated with rapid resolution of the ileus and remarkable improvement in radiographic imaging and clinical phenotype. Prucalopride may be a potential therapeutic option for severe small bowel and colonic ileus in critically ill patients. Further studies are warranted to delineate its safety and efficacy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 7","pages":"e02248"},"PeriodicalIF":0.6,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13395521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148576793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2026-07-23eCollection Date: 2026-07-01DOI: 10.14309/crj.0000000000002249
Lena Sarhan, Serina B Beydoun, Bulent Ozgonenel, Ali G Saad, Sara Evans, Tony Lulgjuraj
{"title":"Severe Anemia in a Child With Newly Diagnosed Celiac Disease and Suspected Parvovirus B19-Associated Erythroid Suppression.","authors":"Lena Sarhan, Serina B Beydoun, Bulent Ozgonenel, Ali G Saad, Sara Evans, Tony Lulgjuraj","doi":"10.14309/crj.0000000000002249","DOIUrl":"10.14309/crj.0000000000002249","url":null,"abstract":"<p><p>Celiac disease (CeD) is an autoimmune disorder triggered by gluten ingestion. While anemia is common due to nutrient malabsorption or chronic inflammation, severe anemia is rare. We present a case of a 5-year-old boy with newly diagnosed CeD who developed severe anemia due to parvovirus B19 (PB19) infection associated with pure red cell aplasia resulting in hospitalization. Evaluation revealed positive PB19 polymerase chain reaction and findings consistent with PB19-pure red cell aplasia. The prolonged infection was likely exacerbated by nutritional and immune compromise from untreated CeD. This case highlights the importance of considering causes of severe anemia beyond nutritional deficiencies in children with CeD.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 7","pages":"e02249"},"PeriodicalIF":0.6,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13395500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148576819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2026-07-23eCollection Date: 2026-07-01DOI: 10.14309/crj.0000000000002250
Neha Narayan, Orrin Wilson, Sherifatu Abu, Zachary Wilmer Reichenbach, David Lichtenstein, Malorie Simons, Nicholas McDonald
{"title":"Endoscopic Ultrasound-Guided Gallbladder Drainage for Acute Cholecystitis in Billroth II Anatomy via Afferent Limb.","authors":"Neha Narayan, Orrin Wilson, Sherifatu Abu, Zachary Wilmer Reichenbach, David Lichtenstein, Malorie Simons, Nicholas McDonald","doi":"10.14309/crj.0000000000002250","DOIUrl":"10.14309/crj.0000000000002250","url":null,"abstract":"<p><p>Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) is an alternative treatment of acute cholecystitis, though there is limited literature on its use in surgically altered anatomy. A 64-year-old woman with gastric adenocarcinoma and Billroth II reconstruction presented with clinical signs and symptoms of acute cholecystitis, cholestatic liver function tests, and an hepatobiliary iminodiacetic acid scan supporting the diagnosis of acute calculous cholecystitis. She was deemed a nonsurgical candidate due to medical comorbidities; therefore, EUS-GBD was pursued. Our case highlights technical modifications to EUS-GBD to navigate challenges in Billroth II anatomy and supports the addition of this technique for high-risk surgical patients.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 7","pages":"e02250"},"PeriodicalIF":0.6,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13395495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148576773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2026-07-23eCollection Date: 2026-07-01DOI: 10.14309/crj.0000000000002257
Daniel Lowe, Kevin Choi, Joo-Shik Shin, Richard Pow, Ken Liu
{"title":"Refractory Ascites After Liver Transplantation due to Splenic Artery Steal Syndrome With Resolution After Splenectomy.","authors":"Daniel Lowe, Kevin Choi, Joo-Shik Shin, Richard Pow, Ken Liu","doi":"10.14309/crj.0000000000002257","DOIUrl":"10.14309/crj.0000000000002257","url":null,"abstract":"<p><p>Postliver transplant ascites occurs in 5%-7% of recipients. This report describes splenic artery steal syndrome, causing refractory post-transplant ascites and ischemic biliopathy requiring splenectomy. A 65-year-old man with alcohol-related cirrhosis underwent orthotopic liver transplantation (Model for End-Stage Liver Disease 12) with pretransplant splenomegaly and splenic-artery dilatation. Postoperatively, computed tomography demonstrated persistent ascites, splenic-to-hepatic artery ratio of 2.5, and reduced hepatic arterial perfusion. Endoscopic retrograde cholangiopancreatography identified an anastomotic stricture with intrahepatic biliopathy. Two splenic artery embolization procedures were unsuccessful. Salvage splenectomy achieved resolution of ascites, cholestasis, and biliopathy. Splenic artery steal syndrome is an under-recognized cause of refractory post-transplant ascites which may benefit from splenectomy after embolization failure.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 7","pages":"e02257"},"PeriodicalIF":0.6,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13395503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148576742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2026-07-20eCollection Date: 2026-07-01DOI: 10.14309/crj.0000000000002242
Yeshika Thapa, Carson Cornell Creamer, Toufic Dabit, Farah Haneyah, Yaseen Perbtani, Tony S Brar
{"title":"Beyond LAMS: Innovative EUS-Guided Needle Drainage With Wall-Apposed Suction Strategy for a Giant Perisplenic Pancreatic Pseudocyst.","authors":"Yeshika Thapa, Carson Cornell Creamer, Toufic Dabit, Farah Haneyah, Yaseen Perbtani, Tony S Brar","doi":"10.14309/crj.0000000000002242","DOIUrl":"10.14309/crj.0000000000002242","url":null,"abstract":"<p><p>Splenic complications occur in approximately 2% of patients with chronic pancreatitis. Standard endoscopic ultrasound (EUS)-guided transmural drainage requires a Doppler-free window and may be unsafe when collaterals traverse the intended tract. We report a 42-year-old woman with alcoholic chronic pancreatitis and splenic vein thrombosis presented with a perisplenic pseudocyst that enlarged from 10.8 to 18.9 cm over 1 month. EUS confirmed intervening vasculature precluding stent placement; a narrow Doppler-free path permitted 19-gauge needle access. Continuous aspiration through a 3-way stopcock system evacuated approximately 1,000 mL with marked decompression. This case highlights EUS-guided needle decompression when vasculature constrains conventional drainage.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 7","pages":"e02242"},"PeriodicalIF":0.6,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13384688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148597706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}