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B-Cell Lymphoma Diagnosed in an Explanted Liver of a Patient With Metabolic Dysfunction-Associated Steatohepatitis Cirrhosis. 代谢功能障碍相关脂肪性肝炎肝硬化患者外植肝诊断b细胞淋巴瘤。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-07 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001656
Lily Kaufman, Hannah Chi, Luke Bushrow, Martha Yearsley, Khalid Mumtaz
{"title":"B-Cell Lymphoma Diagnosed in an Explanted Liver of a Patient With Metabolic Dysfunction-Associated Steatohepatitis Cirrhosis.","authors":"Lily Kaufman, Hannah Chi, Luke Bushrow, Martha Yearsley, Khalid Mumtaz","doi":"10.14309/crj.0000000000001656","DOIUrl":"https://doi.org/10.14309/crj.0000000000001656","url":null,"abstract":"<p><p>Hepatic malignancies in explanted livers are not uncommon; however, finding primary nonhepatic malignancies in explanted livers of any etiology is very rare. Given its rarity, we present a case of low-grade B-cell lymphoma in the liver explant of a patient with metabolic dysfunction-associated steatohepatitis cirrhosis after orthotopic liver transplantation. Preorthotopic liver transplantation workup was notable for periportal lymphadenopathy that was negative for malignancy per ultrasound-guided biopsy, so this finding was surprising. This unexpected diagnosis of lymphoma despite negative workup during pretransplant evaluation underscores the importance for liver transplant centers to conduct thorough investigations for malignancies before transplantation.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01656"},"PeriodicalIF":0.6,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Annular Pancreas Causing Gastric Diverticulum in a 29-Year-Old Man: A Rare Complication of an Uncommon Condition. 环状胰腺引起胃憩室一例29岁男性：罕见情况的罕见并发症。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-07 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001667
Sarpong Boateng, Gabriel Heymann, Frances Mejia, Benjamin A Lerner, Caroline Loeser
{"title":"Annular Pancreas Causing Gastric Diverticulum in a 29-Year-Old Man: A Rare Complication of an Uncommon Condition.","authors":"Sarpong Boateng, Gabriel Heymann, Frances Mejia, Benjamin A Lerner, Caroline Loeser","doi":"10.14309/crj.0000000000001667","DOIUrl":"https://doi.org/10.14309/crj.0000000000001667","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01667"},"PeriodicalIF":0.6,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastroesophageal Intussusception Treated With Combined Transoral Incisionless Fundoplication in a Patient With Systemic Sclerosis. 经口无切口底瓣联合治疗系统性硬化症患者胃食管肠套叠1例。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-05 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001632
Areeka Memon, Nicholas Dugan, Thiruvengadam Muniraj, Monique E Hinchcliff, Amir Masoud
{"title":"Gastroesophageal Intussusception Treated With Combined Transoral Incisionless Fundoplication in a Patient With Systemic Sclerosis.","authors":"Areeka Memon, Nicholas Dugan, Thiruvengadam Muniraj, Monique E Hinchcliff, Amir Masoud","doi":"10.14309/crj.0000000000001632","DOIUrl":"10.14309/crj.0000000000001632","url":null,"abstract":"<p><p>We present a case of a 49-year-old woman with diffuse cutaneous systemic sclerosis with refractory gastroesophageal reflux disease and dysphagia for pills and solid foods. Esophagogastroduodenoscopy revealed gastroesophageal intussusception. Despite several interventions including esophageal stent placement, dysphagia persisted. Owing to refractory severe symptoms, the patient underwent a laparoscopic hiatal hernia repair combined with endoscopic transoral incisionless fundoplication. The patient tolerated the intervention well and dysphagia resolved. Although an obscure persistent dysphagia in SSc patients, gastroesophageal intussusception should be considered. This case underscores the need for persistence in the diagnostic evaluation of gastrointestinal symptoms in patients with SSc and highlights the need for a multidisciplinary team care approach.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01632"},"PeriodicalIF":0.6,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11975402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Duodenal Ulcer and Gastrointestinal Bleeding as a Late Complication of Over-The-Scope Clip Placement. 十二指肠溃疡和胃肠道出血是镜外夹置入的晚期并发症。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-04 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001657
Aditya Avula, Ahmed Al-Chalabi, Erin Jenkins
{"title":"Duodenal Ulcer and Gastrointestinal Bleeding as a Late Complication of Over-The-Scope Clip Placement.","authors":"Aditya Avula, Ahmed Al-Chalabi, Erin Jenkins","doi":"10.14309/crj.0000000000001657","DOIUrl":"https://doi.org/10.14309/crj.0000000000001657","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01657"},"PeriodicalIF":0.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metastatic Breast Cancer to the Esophagus Causing Pseudoachalasia. 转移到食道的乳腺癌引起假性贲门失弛缓症。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-04 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001666
Garrett Teskey, Alexander Prevallet, Rohit Khanna, Franklin Chung-Han Tsai, Walter James Coyle
{"title":"Metastatic Breast Cancer to the Esophagus Causing Pseudoachalasia.","authors":"Garrett Teskey, Alexander Prevallet, Rohit Khanna, Franklin Chung-Han Tsai, Walter James Coyle","doi":"10.14309/crj.0000000000001666","DOIUrl":"10.14309/crj.0000000000001666","url":null,"abstract":"<p><p>A unique case involving a 65-year-old woman with recurrent hormone-positive, HER-2-negative breast cancer stage IV (T2N2M1) with known metastases to the bone presented with worsening dysphagia and esophageal wall thickening on imaging masquerading as achalasia. However, endosonography (EUS)-guided biopsy of the esophagus wall demonstrated metastatic breast cancer to the esophagus causing pseudoachalasia.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01666"},"PeriodicalIF":0.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic Ultrasound-Guided Chemoablation of an Acinar Cell Carcinoma as a Suppressive Strategy for Unresectable Disease. 超声内镜引导下的腺泡细胞癌化疗消融作为不可切除疾病的抑制策略。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-04 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001664
Brandon Rodgers, Matthew T Moyer
{"title":"Endoscopic Ultrasound-Guided Chemoablation of an Acinar Cell Carcinoma as a Suppressive Strategy for Unresectable Disease.","authors":"Brandon Rodgers, Matthew T Moyer","doi":"10.14309/crj.0000000000001664","DOIUrl":"10.14309/crj.0000000000001664","url":null,"abstract":"<p><p>Acinar cell carcinoma is a relatively rare pancreatic neoplasm, typically treated with surgical resection and adjuvant chemotherapy; however, definitive treatment protocols are not well established. We describe endoscopic ultrasound-guided chemoablation with fine needle injection of paclitaxel/gemcitabine in conjunction with chemotherapy in a 78-year-old man with a 3.0 × 2.7-cm acinar cell carcinoma who was not a surgical candidate. At 12 months, the mass had reduced in size to 0.9 × 0.9 cm, followed by steady growth to 6 × 4.5 cm at 24 months when the patient died secondary to unrelated causes.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01664"},"PeriodicalIF":0.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic Submucosal Dissection as a Rescue Therapy for Ineffective Endoscopic Mucosal Resection in Ileal Pouch, Nongranular, Laterally Spreading Tumor. 内镜下粘膜夹层作为内镜下粘膜切除术无效的治疗回肠袋，非颗粒性，侧向扩散肿瘤。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-04 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001651
Giuseppe Grande, Riccardo Casciola, Federico Barbaro, Tommaso Schepis, Silvia Cocca, Salvatore Russo, Helga Bertani, Rita Conigliaro
{"title":"Endoscopic Submucosal Dissection as a Rescue Therapy for Ineffective Endoscopic Mucosal Resection in Ileal Pouch, Nongranular, Laterally Spreading Tumor.","authors":"Giuseppe Grande, Riccardo Casciola, Federico Barbaro, Tommaso Schepis, Silvia Cocca, Salvatore Russo, Helga Bertani, Rita Conigliaro","doi":"10.14309/crj.0000000000001651","DOIUrl":"10.14309/crj.0000000000001651","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01651"},"PeriodicalIF":0.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970823/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Avoiding Premature Antibiotic Use in Recurrent Clostridioides difficile Infection After Fecal Microbiota Transplant. 粪便菌群移植后复发性难辨梭菌感染避免过早使用抗生素。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-03 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001660
Rahim A Burdette, Caroline C Whitt, Brian W Behm, Cirle A Warren
{"title":"Avoiding Premature Antibiotic Use in Recurrent <i>Clostridioides difficile</i> Infection After Fecal Microbiota Transplant.","authors":"Rahim A Burdette, Caroline C Whitt, Brian W Behm, Cirle A Warren","doi":"10.14309/crj.0000000000001660","DOIUrl":"10.14309/crj.0000000000001660","url":null,"abstract":"<p><p>Recurrent <i>Clostridioides difficile</i> infection (rCDI) remains a major clinical challenge, often requiring fecal microbiota transplantation (FMT) after conventional treatment fails. An 86-year-old woman with rCDI underwent FMT after failing multiple antibiotic therapies. Shortly after FMT, she experienced diarrhea and abdominal pain, alongside positive <i>C. difficile</i> stool tests. Antibiotics were withheld because of clinical improvement, and she achieved complete resolution of symptoms without further treatment. This case demonstrates the potential benefit of withholding antibiotics in rCDI patients soon after FMT to allow sufficient time for donor microbiota engraftment and underscores the need for further research to optimize post-FMT management.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01660"},"PeriodicalIF":0.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11968022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunomodulators for Steroid-Dependent Recurrent Acute Pancreatitis After Immune Checkpoint Inhibitor Therapy: A Case Series. 免疫检查点抑制剂治疗后类固醇依赖性复发性急性胰腺炎的免疫调节剂：一个病例系列。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-03 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000001653
Hannah Peck, Wilfredo Pagani, Arianna Smith, Srivats Madhavan
{"title":"Immunomodulators for Steroid-Dependent Recurrent Acute Pancreatitis After Immune Checkpoint Inhibitor Therapy: A Case Series.","authors":"Hannah Peck, Wilfredo Pagani, Arianna Smith, Srivats Madhavan","doi":"10.14309/crj.0000000000001653","DOIUrl":"10.14309/crj.0000000000001653","url":null,"abstract":"<p><p>One to 2% of patients undergoing immune checkpoint inhibitor (ICI) therapy develop ICI-induced pancreatitis (ICI-IP). A small subset of these patients develop recurrent pancreatitis, even after discontinuation of ICI therapy. This case series presents 2 patients with recurrent steroid-responsive ICI-IP who were managed with immunomodulators as steroid-sparing agents. Both patients were maintained on immunomodulators for approximately 2 years before discontinuation of the agents, with no further recurrence or complications of pancreatitis. This case series highlights the use of mycophenolate mofetil and azathioprine for the management of recurrent ICI-IP.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e01653"},"PeriodicalIF":0.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11968019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
De Novo Crohn's Disease 3 Years Following Immune Checkpoint Inhibitor Therapy. 免疫检查点抑制剂治疗后3年新生克罗恩病
IF 0.6
ACG Case Reports Journal Pub Date : 2025-04-03 eCollection Date: 2025-04-01 DOI: 10.14309/crj.0000000000000944
Matthew G Bell, Manuel Bonfim Braga Neto, Sunanda V Kane
{"title":"De Novo Crohn's Disease 3 Years Following Immune Checkpoint Inhibitor Therapy.","authors":"Matthew G Bell, Manuel Bonfim Braga Neto, Sunanda V Kane","doi":"10.14309/crj.0000000000000944","DOIUrl":"10.14309/crj.0000000000000944","url":null,"abstract":"<p><p>Presented is a 76-year-old man with metastatic melanoma that was successfully treated with pembrolizumab, an immune checkpoint inhibitor (ICI). He underwent 20 months of ICI treatment without dose limiting side effects. Nearly 18 months after ICI discontinuation, the patient developed intermittent epigastric pain and diarrhea. Owing to mild symptoms, he was not immediately evaluated. Three years after ICI cessation, he was diagnosed with stricturing, jejunal Crohn's disease. He was treated with vedolizumab and displayed clinical and radiographic response to treatment. This case serves as an example of potential gastrointestinal-related, long-term autoimmune implications of ICI therapy, even in patients without acute side effects.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 4","pages":"e00944"},"PeriodicalIF":0.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11968015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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