ACG Case Reports JournalPub Date : 2025-07-17eCollection Date: 2025-07-01DOI: 10.14309/crj.0000000000001766
Shivani Desai, Katrina A McGinty, Andrew Canakis, Lee-Ching Zhu, Neil D Shah
{"title":"Leave No \"Stone\" Unturned: Biliary Obstruction From Isolated Intraductal Metastatic HCC.","authors":"Shivani Desai, Katrina A McGinty, Andrew Canakis, Lee-Ching Zhu, Neil D Shah","doi":"10.14309/crj.0000000000001766","DOIUrl":"10.14309/crj.0000000000001766","url":null,"abstract":"<p><p>Hepatocellular carcinoma (HCC) metastases to the biliary tree are exceedingly rare. We present a patient with hepatitis C virus (HCV) cirrhosis and recurrent HCC treated previously by locoregional therapy, who presented for Y-90 embolization but was found to have obstructive jaundice. Intraductal biopsy confirmed isolated, metastatic HCC in the distal common bile duct leading to obstruction. Albeit rare, bile duct metastases should be considered in patients with HCC treated by locoregional therapy presenting with obstructive jaundice. To our knowledge, this is the first report of metastatic HCC to the common bile duct in a patient who has not undergone prior partial hepatectomy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01766"},"PeriodicalIF":0.6,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12269809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144658118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-07-14eCollection Date: 2025-07-01DOI: 10.14309/crj.0000000000001765
Aniruddha Srivastava, Luay M Almassalha, Laurens P Janssens, Srinadh Komanduri, Saad Saffo
{"title":"Over-The-Scope Clip Misdeployment Resulting in Acute Cholangitis and Biliary Pancreatitis.","authors":"Aniruddha Srivastava, Luay M Almassalha, Laurens P Janssens, Srinadh Komanduri, Saad Saffo","doi":"10.14309/crj.0000000000001765","DOIUrl":"10.14309/crj.0000000000001765","url":null,"abstract":"<p><p>Over-the-scope clips (OTSCs) have improved the endoscopic management of acute nonvariceal upper gastrointestinal bleeding. They allow for effective hemostasis of high-risk lesions in challenging locations and have been shown to be superior to through-the-scope clips. However, misdeployment of OTSCs may be associated with obstructive complications. In this study, we present the case of a 67-year-old man who developed recurrent gastrointestinal bleeding from a duodenal ulcer. His course was ultimately complicated by acute cholangitis and pancreatitis from a misdeployed OTSC around the ampulla. Endoscopic management was pursued, and the clip was successfully retracted with resolution of his biliary obstruction and subsequent clinical improvement.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01765"},"PeriodicalIF":0.6,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12262945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-07-14eCollection Date: 2025-07-01DOI: 10.14309/crj.0000000000001759
Nihal Ijaz Khan, Saurabh Chandan, Abdullah Abbasi, Sagar Pathak, Kambiz S Kadkhodayan
{"title":"Refractory Benign Duodenal Stenosis Successfully Treated With Endoscopic Spray Cryotherapy.","authors":"Nihal Ijaz Khan, Saurabh Chandan, Abdullah Abbasi, Sagar Pathak, Kambiz S Kadkhodayan","doi":"10.14309/crj.0000000000001759","DOIUrl":"10.14309/crj.0000000000001759","url":null,"abstract":"<p><p>Benign duodenal stenosis is most commonly seen as a complication of peptic ulcer disease. Medical treatments include acid-blocking agents and eradication of <i>Helicobacter pylori</i> infection. While endoscopic balloon dilatation is an effective treatment modality, frequent dilations and ultimately surgical repair are often needed for refractory cases. The role of liquid nitrogen spray-assisted cryoablation has been explored in certain respiratory and anastomotic gastrointestinal strictures. We report a case of persistent benign duodenal stenosis successfully treated with liquid nitrogen spray cryotherapy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01759"},"PeriodicalIF":0.6,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12263004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gastrografin Enema to the Rescue of the Glorious Cecal Bascule.","authors":"Bushra Bangash, Dominique Pean, Guntash Khasria, Ismail Hader","doi":"10.14309/crj.0000000000001752","DOIUrl":"10.14309/crj.0000000000001752","url":null,"abstract":"<p><p>A 74-year-old woman with a history of gastroesophageal reflux disease, hiatal hernia, Barrett's esophagus, chronic obstructive pulmonary disease, and chronic constipation was hospitalized for community-acquired pneumonia. During her hospitalization, she developed progressive lower abdominal discomfort and reported no bowel movement for 8 days. Conservative measures, including oral laxatives, enemas, and manual disimpaction, were unsuccessful, prompting gastroenterology consultation. Imaging revealed colonic pseudo-obstruction with a markedly dilated cecum, suggestive of a type III cecal bascule-a rare upward folding of the cecum without torsion. Owing to her clinical stability, absence of peritoneal signs, and lack of ischemia on imaging, a nonsurgical approach was pursued. The patient was treated with a Gastrografin enema, resulting in immediate decompression and clinical improvement. This case contributes to emerging literature supporting conservative management of cecal bascule in select patients and emphasizes the importance of careful patient selection.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01752"},"PeriodicalIF":0.6,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12263039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-07-10eCollection Date: 2025-07-01DOI: 10.14309/crj.0000000000001758
Disha Sharma, Alla Turshudzhyan, Amanda Urban, David E Kleiner, Theo Heller, Alexandra F Freeman
{"title":"Back With Vengeance: Delayed Gastrointestinal Sequelae of Histoplasmosis in a Patient With STAT3 Hyper-IgE Syndrome.","authors":"Disha Sharma, Alla Turshudzhyan, Amanda Urban, David E Kleiner, Theo Heller, Alexandra F Freeman","doi":"10.14309/crj.0000000000001758","DOIUrl":"10.14309/crj.0000000000001758","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01758"},"PeriodicalIF":0.6,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12262964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-07-07eCollection Date: 2025-07-01DOI: 10.14309/crj.0000000000001762
Brenton G Davis, Max L Goldman, Sarah C Cherny, Angela Y Lam, Jeffrey M Fox
{"title":"Collagenous Gastritis: A Rare Cause of Hemorrhagic Shock.","authors":"Brenton G Davis, Max L Goldman, Sarah C Cherny, Angela Y Lam, Jeffrey M Fox","doi":"10.14309/crj.0000000000001762","DOIUrl":"10.14309/crj.0000000000001762","url":null,"abstract":"<p><p>Collagenous gastritis (CG) is a rare condition comprised 2 phenotypes-pediatric and adult onset. While adult CG often presents with diarrhea, pediatric CG more often manifests with iron deficiency anemia and abdominal pain. Of the relatively few cases described since discovery, treatment has involved oral iron, proton-pump inhibitors, and close follow-up. While 22.5% of pediatric CG involves some form of gastrointestinal bleeding, massive hemorrhage resulting from CG has not previously been described. We present a case of refractory CG diagnosed on endoscopy after hemorrhagic shock due to an acute gastrointestinal bleed requiring both initial and off-label step-up therapy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01762"},"PeriodicalIF":0.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Delayed Presentation of Metastatic Breast Cancer Masquerading as Nonspecific Gastritis.","authors":"Aagamjit Singh, Inayat Gill, Nishant Aggarwal, Atulkumar Patel","doi":"10.14309/crj.0000000000001761","DOIUrl":"10.14309/crj.0000000000001761","url":null,"abstract":"<p><p>Gastric metastasis from breast cancer is often difficult to diagnose due to nonspecific symptoms and variable endoscopic findings. We report a case of a 64-year-old woman with a long history of stable metastatic breast cancer to the spine who presented with new-onset weight loss and nausea. Cross-sectional imaging was negative for cancer spread to the gastrointestinal tract. She was found to have biopsy-proven breast cancer cells in the stomach, despite the absence of gastric lesions in a follow-up positron emission tomography scan. Apart from minimal gastritis, there were no visible nodules, ulcers, or features of linitis plastica on endoscopy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01761"},"PeriodicalIF":0.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-07-07eCollection Date: 2025-07-01DOI: 10.14309/crj.0000000000001764
Oscar Noble, Ramon O Minjares, Rebecca Yorke, Alberto Barroso
{"title":"Elusive Edematous Primary Intestinal Lymphangiectasia in an Adult Patient Presenting With New Onset of Protein-Losing Enteropathy.","authors":"Oscar Noble, Ramon O Minjares, Rebecca Yorke, Alberto Barroso","doi":"10.14309/crj.0000000000001764","DOIUrl":"10.14309/crj.0000000000001764","url":null,"abstract":"<p><p>Primary intestinal lymphangiectasia is a rare disorder characterized by the dilation of lymphatic vessels in the small intestine, resulting in the loss of proteins, particularly albumin, into the gastrointestinal tract which leads to a protein-losing enteropathy. We report the case of a 66-year-old African American man who presented with insidious abdominal pain, chronic diarrhea, hypoalbuminemia, leukopenia, and anemia. An elusive diagnosis of edematous subtype primary intestinal lymphangiectasia with protein-losing enteropathy was confirmed through a multimodal diagnostic approach, including video capsule endoscopy and small bowel endoscopy with biopsies. Treatment was focused on optimizing the patient's nutritional status.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01764"},"PeriodicalIF":0.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144582809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-07-03eCollection Date: 2025-07-01DOI: 10.14309/crj.0000000000001754
Himsikhar Khataniar, Katherine Albus, Inanc S Sarici, Sven E Eriksson, Shahin Ayazi
{"title":"Endoscopic Recanalization of a Long Segment Esophageal Obstruction Using the Combined Antegrade and Retrograde Rendezvous Procedure.","authors":"Himsikhar Khataniar, Katherine Albus, Inanc S Sarici, Sven E Eriksson, Shahin Ayazi","doi":"10.14309/crj.0000000000001754","DOIUrl":"10.14309/crj.0000000000001754","url":null,"abstract":"<p><p>The combined antegrade and retrograde endoscopic rendezvous technique effectively restores patency for esophageal short-segment obstructing strictures (<3 cm). However, long-segment strictures typically require complex surgery, with endoscopic management rarely reported. We report a 44-year-old man with a 9 cm esophageal obstruction due to peptic stricture who was at high risk of esophageal resection due to severe cardiac disease and prior abdominal surgeries. He underwent successful recanalization using a rendezvous technique. Serial dilations with subsequent esophageal stenting restored luminal patency. This case highlights the feasibility of an endoscopic approach as a safe and effective alternative to surgery in long-segment peptic strictures.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01754"},"PeriodicalIF":0.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12225991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144558795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}