ACG Case Reports JournalPub Date : 2025-03-05eCollection Date: 2025-03-01DOI: 10.14309/crj.0000000000001640
Serina Beydoun, James W Davis, Namir Al-Ansari
{"title":"Cecal Duplication Cyst Presenting With Hematochezia.","authors":"Serina Beydoun, James W Davis, Namir Al-Ansari","doi":"10.14309/crj.0000000000001640","DOIUrl":"10.14309/crj.0000000000001640","url":null,"abstract":"<p><p>Enteric duplication cysts are rare congenital anomalies that can present with nonspecific symptoms, making diagnosis difficult. We present a case of a 13-month-old woman with hematochezia, initially diagnosed with viral gastroenteritis, who was later found to have a cecal duplication cyst on imaging. Surgical resection with ileocecectomy was performed, and pathology confirmed the diagnosis of cecal duplication cyst. Early diagnosis and a multidisciplinary approach are essential for preventing complications such as bowel obstruction and perforation, ensuring optimal outcomes.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01640"},"PeriodicalIF":0.6,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143565694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-03-05eCollection Date: 2025-03-01DOI: 10.14309/crj.0000000000001628
Estefania Roldan, Giovanni A Roldan, Jennifer Haglund
{"title":"Primary Jejunal Melanoma Presenting With Intussusception in a Patient With Chronic Iron Deficiency Anemia.","authors":"Estefania Roldan, Giovanni A Roldan, Jennifer Haglund","doi":"10.14309/crj.0000000000001628","DOIUrl":"10.14309/crj.0000000000001628","url":null,"abstract":"<p><p>Primary gastrointestinal (GI) melanomas (PGIMs) are rare, accounting for a small fraction of GI malignancies and particularly uncommon in the small bowel. Diagnosing PGIMs is challenging due to its varied presentations and the difficulty in distinguishing it from metastatic melanoma. We present the case of an 84-year-old man with chronic anemia and intussusception due to primary jejunal melanoma. The patient reported fatigue, dizziness, and chronic anemia. Initial evaluations, including esophagogastroduodenoscopy and colonoscopy, were nondiagnostic. A video capsule endoscopy revealed scattered aphthous ulcers without active bleeding, and computed tomography enterography identified a jejunal mass causing intussusception. Exploratory laparotomy confirmed a 3.5 cm polypoid mass, identified histologically as high-grade malignant melanoma. This case, the first reported instance of primary jejunal melanoma with chronic anemia and intussusception, underscores the diagnostic complexities of PGIMs and emphasizes the importance of imaging and surgical intervention. Awareness of PGIMs in elderly patients with nonspecific GI symptoms is essential.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01628"},"PeriodicalIF":0.6,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143565622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-03-05eCollection Date: 2025-03-01DOI: 10.14309/crj.0000000000001625
Luis E Ospina Velasquez, Konstantinos A Papadakis, Siri A Urquhart
{"title":"Ustekinumab-Induced Vasculitis in a Patient With Crohn's Disease.","authors":"Luis E Ospina Velasquez, Konstantinos A Papadakis, Siri A Urquhart","doi":"10.14309/crj.0000000000001625","DOIUrl":"10.14309/crj.0000000000001625","url":null,"abstract":"<p><p>Immunoglobulin A vasculitis (IgAV) is an immune-mediated disorder that commonly involves dermatologic, musculoskeletal, renal, and gastrointestinal systems. Drug-induced cases of IgAV are rare and sparsely documented in the literature. We report a case of a patient with Crohn's disease who developed a tender, palpable purpuric rash on the torso and extremities 3 weeks after receiving a dose of ustekinumab. This case underscores the importance of considering IgAV in patients with inflammatory bowel disease who present with cutaneous symptoms while undergoing treatment with advanced therapies.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01625"},"PeriodicalIF":0.6,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143565626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unusual Suspect: Ménétrier Disease Presents as Gastric Outlet Obstruction in a Toddler.","authors":"Kalpana Panda, Debashree Priyadarshini, J Bikrant Kumar Prusty, Rachita Sarangi, Anuspandana Mahapatra, Bibhuti Bhusan Dalei, Subhashis Mohanty, Girish Kumar Pati","doi":"10.14309/crj.0000000000001630","DOIUrl":"10.14309/crj.0000000000001630","url":null,"abstract":"<p><p>Ménétrier disease (MD) is a rare condition characterized by hypertrophic gastropathy, leading to enlarged gastric folds, excessive mucus production, and protein loss. Among the approximately 150 cases of reported pediatric MD, the usual presenting features are peripheral oedema, anasarca, and gastrointestinal symptoms. This case report describes a 2-year-old child presenting with gastric outlet obstruction, an unusual manifestation of MD, which has not been described previously in the pediatric age group.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01630"},"PeriodicalIF":0.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11878991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-03-03eCollection Date: 2025-03-01DOI: 10.14309/crj.0000000000001635
Joel Gabin Konlack Mekontso, Akil Olliverrie, Jingwei Ren, Veronika Stefanishina, Syed Karim, Shahbaz Khan, Thomas McIntyre, Mohammad Choudhry
{"title":"Unicentric Castleman Disease Coexisting With Type 2 Autoimmune Pancreatitis: A Case Report Mimicking Pancreatic Cancer and Near-Whipple Surgery.","authors":"Joel Gabin Konlack Mekontso, Akil Olliverrie, Jingwei Ren, Veronika Stefanishina, Syed Karim, Shahbaz Khan, Thomas McIntyre, Mohammad Choudhry","doi":"10.14309/crj.0000000000001635","DOIUrl":"10.14309/crj.0000000000001635","url":null,"abstract":"<p><p>This case describes a 46-year-old man presenting with epigastric pain, weight loss, and obstructive jaundice, initially misdiagnosed as pancreatic cancer due to a pancreatic head mass compressing the common bile duct. Intraoperative biopsies during an aborted Whipple procedure revealed coexisting autoimmune pancreatitis and Castleman disease. This case highlights the diagnostic challenges of Castleman disease, its potential association with autoimmune pancreatitis, and the critical role of histological analysis in differentiating it from malignancy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01635"},"PeriodicalIF":0.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11878988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-02-27eCollection Date: 2025-03-01DOI: 10.14309/crj.0000000000001633
Ryan Njeim, Mohammad Abureesh, Yashna Singh, Youssef El Douaihy
{"title":"Unexpected Discovery at Resection Site: Plasmablastic Lymphoma After Polypectomy.","authors":"Ryan Njeim, Mohammad Abureesh, Yashna Singh, Youssef El Douaihy","doi":"10.14309/crj.0000000000001633","DOIUrl":"https://doi.org/10.14309/crj.0000000000001633","url":null,"abstract":"<p><p>Plasmablastic lymphoma (PBL) is a rare, aggressive subtype of diffuse large B-cell lymphoma that has usually been associated with human immunodeficiency virus and Ebstein-Barr virus infections. Commonly seen in the oral cavity, it can affect any part of the gastrointestinal tract. This report describes a unique case of PBL that appeared in an 81-year-old immunocompetent patient. During an initial colonoscopy, a 2-cm polyp in the distal transverse colon was removed via full-thickness resection with pathology showing tubular adenoma with foci of high-grade dysplasia. After 7 months, a repeat colonoscopy found a 3-cm sessile polyp at the site of resection, which, after removal, was found to be a PBL. This is the first case described in the literature regarding the growth of PBL after full-thickness resection of a tubular adenoma in such a short interval.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01633"},"PeriodicalIF":0.6,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11868435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143539757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-02-26eCollection Date: 2025-03-01DOI: 10.14309/crj.0000000000001627
Charles D Evers, Aishwarya Ravindran, Frida Rosenblum, Frederick Weber
{"title":"A Pelvic Mass in a Young Patient With Crohn's Disease.","authors":"Charles D Evers, Aishwarya Ravindran, Frida Rosenblum, Frederick Weber","doi":"10.14309/crj.0000000000001627","DOIUrl":"10.14309/crj.0000000000001627","url":null,"abstract":"<p><p>Castleman disease (CD) is a rare group of lymphoproliferative disorders subdivided based on clinical features. Although not fully understood, the pathogenesis of both CD and Crohn's disease involves a combination of immune dysregulation and infectious and environmental factors. Interleukin-6, a proinflammatory cytokine, is associated with both diseases and can serve as a common therapeutic target in CD. We report a rare case of coexisting unicentric Castleman disease in a young patient with Crohn's disease.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01627"},"PeriodicalIF":0.6,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-02-26eCollection Date: 2025-03-01DOI: 10.14309/crj.0000000000001636
Khushbu Patel, Jenny Jan, Brooke Glessing, Gregory Cooper
{"title":"A Rare Case of Esophageal Pseudodiverticulosis Associated With Cytomegalovirus Esophagitis Presenting With Severe Upper Gastrointestinal Bleeding.","authors":"Khushbu Patel, Jenny Jan, Brooke Glessing, Gregory Cooper","doi":"10.14309/crj.0000000000001636","DOIUrl":"10.14309/crj.0000000000001636","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01636"},"PeriodicalIF":0.6,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-02-26eCollection Date: 2025-03-01DOI: 10.14309/crj.0000000000001624
Jacob A Ciricillo, Farrah Rahim, Yeshika Sharma
{"title":"Unveiling the Genetic Culprit: A Diagnostic Dilemma of Recurrent Cholestasis With Intrahepatic Stones.","authors":"Jacob A Ciricillo, Farrah Rahim, Yeshika Sharma","doi":"10.14309/crj.0000000000001624","DOIUrl":"10.14309/crj.0000000000001624","url":null,"abstract":"<p><p>Recurrent cholestasis poses diagnostic challenges and necessitates repeated testing. The <i>ABCB4</i> (adenosine triphosphate-binding cassette, subfamily B, member 4) gene encodes a protein that removes phospholipids from the hepatic canalicular membrane through bile salts. Mutations lead to a spectrum of clinical syndromes that cause recurrent cholestasis, pruritus, and jaundice. This case follows a young female with recurrent cholestasis postcholecystectomy, intrahepatic stones on endoscopic retrograde cholangiopancreatography, and repeated intrahepatic cholestasis of pregnancy. Phenotypes of <i>ABCB4</i> mutations should be considered when facing cholestasis of unclear etiology. Early genetic testing and ursodeoxycholic acid treatment may prevent progression toward hepatic fibrosis and end-stage liver disease.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01624"},"PeriodicalIF":0.6,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-02-26eCollection Date: 2025-03-01DOI: 10.14309/crj.0000000000001638
Miriam Chinzon, Sergio Barbosa Marques, Eduardo Guimarães Hourneaux de Moura
{"title":"Extensive Esophageal Papillomatosis: A Rare Disease With Difficult Diagnosis.","authors":"Miriam Chinzon, Sergio Barbosa Marques, Eduardo Guimarães Hourneaux de Moura","doi":"10.14309/crj.0000000000001638","DOIUrl":"10.14309/crj.0000000000001638","url":null,"abstract":"<p><p>Extensive esophageal papillomatosis is a rare condition with uncertain pathophysiology. We present a case involving a 78-year-old woman, with no notable habits or addictions, who presented with dysphagia and weight loss. She was diagnosed with extensive esophageal papillomatosis, causing esophageal substenosis. Diagnosis of dysplasia in such cases are challenging, and management of the risk of malignant transformation remains uncertain.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01638"},"PeriodicalIF":0.6,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}