ACG Case Reports JournalPub Date : 2025-06-09eCollection Date: 2025-06-01DOI: 10.14309/crj.0000000000001728
Elona Poltiyelova, Natalie Balassiano, Saphwat L Eskaros
{"title":"Co-occurrence of Gastric Xanthoma and Numerous Large Hyperplastic Polyps as a Complication of Argon Plasma Coagulation in GAVE.","authors":"Elona Poltiyelova, Natalie Balassiano, Saphwat L Eskaros","doi":"10.14309/crj.0000000000001728","DOIUrl":"10.14309/crj.0000000000001728","url":null,"abstract":"<p><p>Gastric antral vascular ectasia is a form of gastrointestinal bleeding commonly treated with argon plasma coagulation (APC). APC is a noncontact electrocoagulation technique that transmits energy through ionized argon gas, ultimately coagulating and cauterizing the bleeding vessels. We report a rare case describing an association between APC therapy for gastric antral vascular ectasia and the subsequent development of hyperplastic polyps and gastric xanthoma. This outcome underscores the need for further research into refined treatment strategies to prevent such complications and highlights the importance of recognizing this complication and understanding its risk factors.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01728"},"PeriodicalIF":0.6,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12147997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unraveling the Mystery of Persistent Positional Borborygmi.","authors":"Namit Gupta, Gaurav Kumar Gupta, Mukesh Jain, Hemendra Bhardwaj, Mohammed Mohsin, Narendra Bishoni, Sandeep Nijhawan","doi":"10.14309/crj.0000000000001727","DOIUrl":"10.14309/crj.0000000000001727","url":null,"abstract":"<p><p>We present a case report of young thin-built woman with persistent positional abnormal abdominal sounds audible only while sitting or standing and relieved in supine position. Sounds become more prominent on heavy meals and deep inhalation and improved with breath-holding or self-applying local pressure. Routine investigations, including esophagogastroduodenoscopy, colonoscopy, and contrast-enhance computed tomography of whole abdomen, all were normal. Interestingly, a barium study in standing position revealed an hourglass-shaped stomach, but while in lying down position showed normal anatomy, which might be due to compression of stomach with rib cage. The patient was managed conservatively with medical management, and no definitive medical therapy is available to date.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01727"},"PeriodicalIF":0.6,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-06-05eCollection Date: 2025-06-01DOI: 10.14309/crj.0000000000001726
Fahd Jowhari, David J Hurlbut
{"title":"The Curious Case of Gallbladder Duplication.","authors":"Fahd Jowhari, David J Hurlbut","doi":"10.14309/crj.0000000000001726","DOIUrl":"10.14309/crj.0000000000001726","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01726"},"PeriodicalIF":0.6,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-06-05eCollection Date: 2025-06-01DOI: 10.14309/crj.0000000000001723
Akhila Chilakala, Brenton G Davis, Christopher M Hamerski
{"title":"A Rare Presentation of Benign Vaterian Adenomyoma With High-Grade Adenomatous Dysplasia.","authors":"Akhila Chilakala, Brenton G Davis, Christopher M Hamerski","doi":"10.14309/crj.0000000000001723","DOIUrl":"10.14309/crj.0000000000001723","url":null,"abstract":"<p><p>Benign neoplasms of the ampulla of Vater are infrequently encountered: overall adenomas account for <10% of ampullary neoplasms; adenomyomas are even rarer. This report describes the case of a 78-year-old woman who presented with epigastric pain, elevated lipase and transaminases with imaging notable for acute pancreatitis, and intrahepatic and common bile duct biliary dilatation without choledocholithiasis. A 25-mm ampullary mass was identified during esophagogastroduodenoscopy with endoscopic ultrasound. The mass was determined to be suitable for endoscopic mucosal resection, which was subsequently performed. Histological examination confirmed a benign submucosal Vaterian adenomyoma with overlying mucosal high-grade glandular adenomatous dysplasia. This presentation is exceptionally rare in clinical practice.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01723"},"PeriodicalIF":0.6,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-06-05eCollection Date: 2025-06-01DOI: 10.14309/crj.0000000000001717
Anoushka Dua, Tara Narasimhalu, Sepehr Hamidi, Rohit Dewan, Benjamin Nulsen
{"title":"Tumoral Melanosis of the Colon: A Rare Manifestation of Regressed Melanoma.","authors":"Anoushka Dua, Tara Narasimhalu, Sepehr Hamidi, Rohit Dewan, Benjamin Nulsen","doi":"10.14309/crj.0000000000001717","DOIUrl":"10.14309/crj.0000000000001717","url":null,"abstract":"<p><p>Tumoral melanosis (TM) is a rare manifestation of a benign, completely regressed malignant melanoma and mimics malignant melanoma. These lesions are often found in patients with a history of known or undiscovered metastatic melanoma at or around areas of prior malignancy, commonly on the skin. We describe a rare case of TM discovered in the colon on routine screening colonoscopy in a patient with a history of metastatic melanoma who was responding well to systemic immunotherapy. The pigmented lesion, although endoscopically malignant-appearing, was found on histopathology to be a benign accumulation of melanin-laden macrophages, consistent with TM.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01717"},"PeriodicalIF":0.6,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-06-05eCollection Date: 2025-06-01DOI: 10.14309/crj.0000000000001734
Susanne Sonal, Hatem Kaseb
{"title":"An Unusual Case of Diffuse Large B-Cell Lymphoma of the Common Bile Duct.","authors":"Susanne Sonal, Hatem Kaseb","doi":"10.14309/crj.0000000000001734","DOIUrl":"10.14309/crj.0000000000001734","url":null,"abstract":"<p><p>Diffuse large B-cell lymphoma (DLBCL) of the common bile duct (CBD) is extremely rare. A 77-year-old male patient presented with obstructive jaundice, weight loss, and abdominal pain. An endoscopic retrograde cholangiography revealed a stricture in the common hepatic duct. Biopsy and cytology specimens performed were inconclusive. A pancreaticoduodenectomy revealed a final diagnosis of DLBCL of the CBD. DLBCL of the CBD usually presents with vague symptoms. The definitive diagnosis of DLBCL-CBD can only be rendered by immunomorphological assessment and based on careful exclusion of other nodal and extranodal sites.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01734"},"PeriodicalIF":0.6,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-06-04eCollection Date: 2025-06-01DOI: 10.14309/crj.0000000000001707
Bridgette B McNally, Margaret C Liu, Tisha Lunsford, Jennifer Horsley-Silva, Karen Swanson, Thomas Byrne, Marcela Salomao, Maxwell Smith, Rosita Frazier
{"title":"Refractory Diarrhea Related to EPHB4 Mutation in a Patient With Capillary Malformation-Arteriovenous Type 2 Syndrome.","authors":"Bridgette B McNally, Margaret C Liu, Tisha Lunsford, Jennifer Horsley-Silva, Karen Swanson, Thomas Byrne, Marcela Salomao, Maxwell Smith, Rosita Frazier","doi":"10.14309/crj.0000000000001707","DOIUrl":"10.14309/crj.0000000000001707","url":null,"abstract":"<p><p>Capillary malformation-arteriovenous type 2 syndrome (CM-AVM2) is a rare, genetic vascular disorder associated with abnormal capillary malformations and arteriovenous malformations. We present a case of CM-AVM2 with refractory diarrhea and failure to thrive due to aberrant, telangiectatic capillaries, and subepithelial collagen deposition found throughout the GI tract on bidirectional endoscopy. The patient was recalcitrant to standard therapies, so bevacizumab was trialed, but the patient expired. This is the first case of CM-AVM2 with diffuse GI mucosal involvement resulting in malabsorption. There is no treatment for this pathology, but treatment with bevacizumab or a mammalian target of rapamycin inhibitor may be efficacious.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01707"},"PeriodicalIF":0.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144223994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-06-04eCollection Date: 2025-06-01DOI: 10.14309/crj.0000000000001720
Cathy Zheng, Robert Mowery, Sareena Ali, Camilla Allen, Ryan T Hoff
{"title":"Esophageal Granular Cell Tumor Associated With Eosinophilic Gastrointestinal Disease.","authors":"Cathy Zheng, Robert Mowery, Sareena Ali, Camilla Allen, Ryan T Hoff","doi":"10.14309/crj.0000000000001720","DOIUrl":"10.14309/crj.0000000000001720","url":null,"abstract":"<p><p>Granular cell tumors (GCTs) are typically benign lesions that can occur in the gastrointestinal tract. Eosinophilic gastrointestinal disease, including eosinophilic esophagitis (EoE), is an immune-mediated condition characterized by eosinophil-predominant inflammation in the gastrointestinal tract. We review previously reported cases of EoE associated with GCTs. To our knowledge, we present the first case of esophageal GCT in a patient with a long history of eosinophilic gastrointestinal disease and likely several years of active EoE before esophageal GCT diagnosis.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01720"},"PeriodicalIF":0.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144223993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-05-30eCollection Date: 2025-06-01DOI: 10.14309/crj.0000000000001716
Tara Alleyasin, Evan Wilder, Warren Reidel, Emma Du, Quan M Nhu
{"title":"Treatment of Autoimmune Enteropathy With Vedolizumab.","authors":"Tara Alleyasin, Evan Wilder, Warren Reidel, Emma Du, Quan M Nhu","doi":"10.14309/crj.0000000000001716","DOIUrl":"10.14309/crj.0000000000001716","url":null,"abstract":"<p><p>Autoimmune enteropathy (AIE) is a rare condition characterized by immune-mediated villous atrophy with associated chronic diarrhea. In this case, a 34-year-old man with AIE was treated with vedolizumab, an anti-ɑ4b7 integrin that inhibits intestinal lymphocyte trafficking, after initial treatments with prednisone, open-capsule budesonide, azathioprine, infliximab, and adalimumab showed minimal response. Vedolizumab resulted in moderate symptomatic and histological improvement but was discontinued due to possible drug-induced liver injury. This case suggests the potential therapeutic efficacy of vedolizumab in treating AIE, though more research is needed.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01716"},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}