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Extensive Perianal Basal Cell Carcinoma Presenting With Severe Anorectal Dysfunction. 广泛的肛周基底细胞癌表现为严重的肛肠功能障碍。
IF 0.6
ACG Case Reports Journal Pub Date : 2026-10-09 eCollection Date: 2026-10-01 DOI: 10.14309/crj.0000000000002361
Sebastian Arambulo-Castillo, Maria Alejandra Gutierrez-Luque, Josh Elefteratos, Lingyu Bao, Grace Kajita, Hilary Hertan
{"title":"Extensive Perianal Basal Cell Carcinoma Presenting With Severe Anorectal Dysfunction.","authors":"Sebastian Arambulo-Castillo, Maria Alejandra Gutierrez-Luque, Josh Elefteratos, Lingyu Bao, Grace Kajita, Hilary Hertan","doi":"10.14309/crj.0000000000002361","DOIUrl":"https://doi.org/10.14309/crj.0000000000002361","url":null,"abstract":"<p><p>Perianal basal cell carcinoma is an exceedingly rare malignancy that may mimic benign anorectal conditions or anal squamous cell carcinoma. We report an 84-year-old man with a several-year history of a progressively enlarging circumferential perianal lesion, complicated by constipation, chronic fecal incontinence, bleeding, and significant weight loss. Examination revealed a 15 cm ulcerated tumor involving the entire anal verge, with biopsy confirming basal cell carcinoma and sparing of the anal canal mucosa. Imaging showed fecal impaction and perianal soft tissue thickening without metastasis. Given extensive involvement, vismodegib was initiated. This case highlights the importance of early biopsy of atypical perianal lesions.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 10","pages":"e02361"},"PeriodicalIF":0.6,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13652447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149163565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytomegalovirus Hepatitis Occurring in a Young Patient With Autoimmune Polyglandular Syndrome and Pediatric-Onset Autoimmune Hepatitis. 巨细胞病毒性肝炎发生在自身免疫性多腺综合征和儿科自身免疫性肝炎的年轻患者中。
IF 0.6
ACG Case Reports Journal Pub Date : 2026-10-09 eCollection Date: 2026-10-01 DOI: 10.14309/crj.0000000000002363
Jacqueline R Krieger, David A Sass, Jesse M Civan, Dagan E Coppock, Katherine A Belden, Jonathan M Fenkel
{"title":"Cytomegalovirus Hepatitis Occurring in a Young Patient With Autoimmune Polyglandular Syndrome and Pediatric-Onset Autoimmune Hepatitis.","authors":"Jacqueline R Krieger, David A Sass, Jesse M Civan, Dagan E Coppock, Katherine A Belden, Jonathan M Fenkel","doi":"10.14309/crj.0000000000002363","DOIUrl":"https://doi.org/10.14309/crj.0000000000002363","url":null,"abstract":"<p><p>Cytomegalovirus (CMV) hepatitis is rare in patients with autoimmune hepatitis (AIH) on long-term immunosuppression. We report a 28-year-old woman with a history of autoimmune polyglandular syndrome and pediatric-onset AIH who presented with fatigue, fever, and elevated liver enzymes, found to have CMV hepatitis without active AIH. Early initiation of antiviral therapy led to normalization of liver function tests and resolution of viremia. This case highlights the importance of early diagnosis of CMV hepatitis and the therapeutic challenge of treating CMV while also reintroducing immunosuppression for AIH.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 10","pages":"e02363"},"PeriodicalIF":0.6,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13652472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Esophageal Dysphagia Associated With Left Hemidiaphragm Elevation and Postsurgical Anatomical Distortion. 食管吞咽困难与左膈抬高及术后解剖畸变相关。
IF 0.6
ACG Case Reports Journal Pub Date : 2026-10-09 eCollection Date: 2026-10-01 DOI: 10.14309/crj.0000000000002298
Mohammadreza Zarisfi, Daniel Marino, Scott M Smukalla
{"title":"Esophageal Dysphagia Associated With Left Hemidiaphragm Elevation and Postsurgical Anatomical Distortion.","authors":"Mohammadreza Zarisfi, Daniel Marino, Scott M Smukalla","doi":"10.14309/crj.0000000000002298","DOIUrl":"https://doi.org/10.14309/crj.0000000000002298","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 10","pages":"e02298"},"PeriodicalIF":0.6,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13652468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149163909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of Refractory Gastroparesis With Laparoscopic Sleeve Gastrectomy and Pyloroplasty Leading to Symptom Improvement and Increased Gastric Emptying: First Clinical Experience in a Canadian Center. 腹腔镜袖式胃切除术和幽门成形术治疗难治性胃轻瘫导致症状改善和胃排空增加：加拿大中心的首次临床经验。
IF 0.6
ACG Case Reports Journal Pub Date : 2026-10-09 eCollection Date: 2026-10-01 DOI: 10.14309/crj.0000000000002350
Scott MacKay, Vickie Ringuette, Noah J Switzer, David Yi Yang
{"title":"Treatment of Refractory Gastroparesis With Laparoscopic Sleeve Gastrectomy and Pyloroplasty Leading to Symptom Improvement and Increased Gastric Emptying: First Clinical Experience in a Canadian Center.","authors":"Scott MacKay, Vickie Ringuette, Noah J Switzer, David Yi Yang","doi":"10.14309/crj.0000000000002350","DOIUrl":"https://doi.org/10.14309/crj.0000000000002350","url":null,"abstract":"<p><p>Laparoscopic sleeve gastrectomy (LSG) and pyloroplasty have been identified as treatment options for gastroparesis refractory to dietary, medical, gastric electrical stimulation, and advanced endoscopic therapies (ie, gastric peroral endoscopic myotomy). This case outlines the management of refractory idiopathic gastroparesis in a 62-year-old man who underwent LSG and pyloroplasty with successful improvements in patient-reported symptoms, gastric emptying rate, and weight gain. This is the first reported case of combined LSG and pyloroplasty being used to treat refractory gastroparesis in a Canadian center and adds to a growing body of evidence that LSG and pyloroplasty can be efficacious for refractory gastroparesis.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 10","pages":"e02350"},"PeriodicalIF":0.6,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13652363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149163943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Cholangioscopy-Guided Stone Extraction in a Choledocholithiasis Patient With Afferent Loop Stenosis After Pancreaticoduodenectomy. 胆道镜引导下胆总管结石取出成功治疗胰十二指肠切除术后传入袢狭窄的胆总管结石患者。
IF 0.6
ACG Case Reports Journal Pub Date : 2026-10-05 eCollection Date: 2026-10-01 DOI: 10.14309/crj.0000000000002333
Zhi An, Jian Shang, Qiu Zhao, Jun Fang
{"title":"Successful Cholangioscopy-Guided Stone Extraction in a Choledocholithiasis Patient With Afferent Loop Stenosis After Pancreaticoduodenectomy.","authors":"Zhi An, Jian Shang, Qiu Zhao, Jun Fang","doi":"10.14309/crj.0000000000002333","DOIUrl":"https://doi.org/10.14309/crj.0000000000002333","url":null,"abstract":"<p><p>Choledocholithiasis after pancreaticoduodenectomy is difficult to manage because surgically altered anatomy limits conventional endoscopic access. This difficulty is compounded when afferent loop stenosis is present. We report a 53-year-old man with a previous pancreaticoduodenectomy who presented with abdominal pain and fever. Imaging revealed common bile duct stones. During endoscopic retrograde cholangiopancreatography, severe afferent loop stenosis prevented duodenoscope advancement and guidewire cannulation. The peroral eyeMAX cholangioscope was then used; its slim profile allowed traversal of the stenosis, enabling direct visualization and balloon-assisted stone extraction. This case highlights peroral cholangioscopy as an effective rescue option in this difficult setting.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 10","pages":"e02333"},"PeriodicalIF":0.6,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13632974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149102856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ectopic Duodenal Varices Secondary to Portal Hypertension Caused by Primary Hepatic Neuroendocrine Tumor. 原发性肝神经内分泌肿瘤致门静脉高压继发异位十二指肠静脉曲张。
IF 0.6
ACG Case Reports Journal Pub Date : 2026-10-01 DOI: 10.14309/crj.0000000000002351
Muhammad Umar Saddique, Ahmed Abdulhafedh Ahmed Ali, Souraia Mezhoud Ghazouani
{"title":"Ectopic Duodenal Varices Secondary to Portal Hypertension Caused by Primary Hepatic Neuroendocrine Tumor.","authors":"Muhammad Umar Saddique, Ahmed Abdulhafedh Ahmed Ali, Souraia Mezhoud Ghazouani","doi":"10.14309/crj.0000000000002351","DOIUrl":"https://doi.org/10.14309/crj.0000000000002351","url":null,"abstract":"<p><p>Primary hepatic neuroendocrine tumors (PHNETs) are rare, often presenting with abdominal pain, carcinoid syndrome, or incidental imaging findings. PHNET-associated portal hypertension is uncommon. A 45-year-old man with known PHNET presented with massive upper gastrointestinal bleeding from a duodenal ectopic varix and hemorrhagic shock. Emergent esophagogastroduodenoscopy achieved hemostasis with hemoclips. He subsequently developed high-serum-ascites albumin gradient (1.4 g/dL); imaging showed a 23-cm hepatic mass, portal vein dilatation, and splenomegaly. Liver biopsy confirmed a well-differentiated neuroendocrine neoplasm without cirrhosis, supporting tumor-related, noncirrhotic portal hypertension likely from mechanical vascular compression. This case highlights the rare cause of variceal bleeding due to noncirrhotic portal hypertension in patients with PHNET.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 10","pages":"e02351"},"PeriodicalIF":0.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13629838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149102890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital Microgastria With Esophageal Stricture: An Extremely Rare Foregut Anomaly Necessitating Early Surgical Intervention. 先天性小胃伴食管狭窄：一种极其罕见的前肠异常，需要早期手术干预。
IF 0.6
ACG Case Reports Journal Pub Date : 2026-10-01 DOI: 10.14309/crj.0000000000002349
Arpit Gupta, Ajay Aravind, Anshu Srivastava, Ankur Mandelia, Moinak Sen Sarma
{"title":"Congenital Microgastria With Esophageal Stricture: An Extremely Rare Foregut Anomaly Necessitating Early Surgical Intervention.","authors":"Arpit Gupta, Ajay Aravind, Anshu Srivastava, Ankur Mandelia, Moinak Sen Sarma","doi":"10.14309/crj.0000000000002349","DOIUrl":"https://doi.org/10.14309/crj.0000000000002349","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 10","pages":"e02349"},"PeriodicalIF":0.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13629837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149102841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed Cutaneous Metastases From Gastric Cancer: 20 Years Later. 胃癌延迟皮肤转移：20年后。
IF 0.6
ACG Case Reports Journal Pub Date : 2026-10-01 DOI: 10.14309/crj.0000000000002337
Shingo Ogiwara, Makoto Furihata, Taro Osada
{"title":"Delayed Cutaneous Metastases From Gastric Cancer: 20 Years Later.","authors":"Shingo Ogiwara, Makoto Furihata, Taro Osada","doi":"10.14309/crj.0000000000002337","DOIUrl":"https://doi.org/10.14309/crj.0000000000002337","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 10","pages":"e02337"},"PeriodicalIF":0.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13629835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149102885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adenocarcinoma of the Duodenojejunal Flexure in a Patient With Intestinal Nonrotation. 肠不旋转患者的十二指肠空肠弯曲腺癌。
IF 0.6
ACG Case Reports Journal Pub Date : 2026-09-30 eCollection Date: 2026-10-01 DOI: 10.14309/crj.0000000000002317
Ankuriti Singla, Arshia Bhardwaj, Arshdeep Singh, Kamini Gupta, Akriti Jindal, Puneet Bhutani, Satpal Singh Virk, Vandana Midha, Ajit Sood
{"title":"Adenocarcinoma of the Duodenojejunal Flexure in a Patient With Intestinal Nonrotation.","authors":"Ankuriti Singla, Arshia Bhardwaj, Arshdeep Singh, Kamini Gupta, Akriti Jindal, Puneet Bhutani, Satpal Singh Virk, Vandana Midha, Ajit Sood","doi":"10.14309/crj.0000000000002317","DOIUrl":"https://doi.org/10.14309/crj.0000000000002317","url":null,"abstract":"<p><p>Small bowel adenocarcinoma involving the duodenojejunal (DJ) flexure is rare, and its coexistence with intestinal nonrotation is exceptionally uncommon. A 53-year-old man presented with postprandial fullness, recurrent vomiting, and weight loss. Imaging revealed intestinal nonrotation and a malignant lesion involving the fourth part of the duodenum and DJ flexure. Histopathology confirmed moderately differentiated adenocarcinoma. The patient underwent segmental resection with R0 margins and had an uneventful recovery.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 10","pages":"e02317"},"PeriodicalIF":0.6,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13626686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149102824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-World Experience of Risankizumab in Refractory Pediatric Inflammatory Bowel Disease. 利桑单抗治疗难治性儿童炎症性肠病的现实经验
IF 0.6
ACG Case Reports Journal Pub Date : 2026-09-29 eCollection Date: 2026-10-01 DOI: 10.14309/crj.0000000000002316
Ali Alsarhan, Balaji Krishnamurthy, Eman Elyyan, Mohammad Alhajjar, Christos Tzivinikos
{"title":"Real-World Experience of Risankizumab in Refractory Pediatric Inflammatory Bowel Disease.","authors":"Ali Alsarhan, Balaji Krishnamurthy, Eman Elyyan, Mohammad Alhajjar, Christos Tzivinikos","doi":"10.14309/crj.0000000000002316","DOIUrl":"10.14309/crj.0000000000002316","url":null,"abstract":"<p><p>The incidence of pediatric inflammatory bowel disease (IBD) is rising globally. Anti-tumor necrosis factor agents remain the mainstay of treatment, but a significant number of patients experience treatment failure. This case-series presents real-world experience using risankizumab, an IL-23 inhibitor, in 9 children with severe-refractory IBD. Multiple biologics had failed in all patients before initiation. Response was assessed using symptoms, biomarkers, endoscopy, and imaging. Five patients achieved clinical remission, and 4 failed to achieve complete remission. Noninvasive monitoring tools, such as intestinal ultrasound, were used. No adverse events were reported. Risankizumab may be a promising option in refractory pediatric IBD.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"13 10","pages":"e02316"},"PeriodicalIF":0.6,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13623279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149079323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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