Incidental Detection of Neoplastic B Cells in the Colon Following Resection in a Patient With Adenocarcinoma.

IF 0.5 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2025-09-29 eCollection Date: 2025-10-01 DOI:10.14309/crj.0000000000001844

Asrita Vattikonda, Hasan Saleh, Ian Dryden, Maoyin Pang

引用次数: 0

Abstract

Following a routine screening colonoscopy, a 54-year-old man underwent colon resection for adenocarcinoma, which revealed neoplastic B-cells in the lymph nodes surrounding the colon suggestive of chronic lymphocytic leukemia (CLL). Further evaluation identified a monoclonal B-cell population, and he was diagnosed with monoclonal B-cell lymphocytosis without meeting CLL diagnostic criteria. The patient had no clinical signs of leukemia and did not need acute treatment but was placed under annual surveillance. This case highlights the incidental discovery of neoplastic B-cells, emphasizing the importance of comprehensive histopathological evaluation and clinical correlation to guide management and monitoring for potential progression to CLL.

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腺癌患者结肠切除术后肿瘤B细胞的偶然检测。

在常规结肠镜检查后，54岁男性行结肠腺癌切除术，结肠周围淋巴结肿瘤b细胞提示慢性淋巴细胞白血病（CLL）。进一步的评估发现单克隆b细胞群，他被诊断为单克隆b细胞淋巴细胞增多症，不符合CLL的诊断标准。患者没有白血病的临床症状，不需要急性治疗，但每年进行监测。该病例强调了偶然发现的肿瘤b细胞，强调了综合组织病理学评估和临床相关性的重要性，以指导管理和监测潜在的CLL进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.