孤立性胃克罗恩病

IF 0.5 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2025-09-24 eCollection Date: 2025-09-01 DOI:10.14309/crj.0000000000001790

Matthew Udine, Andres Rodriguez, Ankita Tirath, Heba Iskandar

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引用次数: 0

摘要

孤立性胃克罗恩病（IGCD）是克罗恩病的一个罕见的亚群，在文献中描述很少。在这篇文章中，我们报告了一个21岁的男性胃出口梗阻继发于IGCD。阿达木单抗和Upadacitinib治疗失败，但他对Risankizumab有反应。据我们所知，这是第一个记录利桑单抗治疗IGCD疗效的病例报告。此外，我们回顾了13例已发表的描述IGCD的病例报告。92%的病例为女性，通常表现为恶心/呕吐和腹痛。85%的病例进展为胃出口梗阻，肿瘤坏死因子抑制剂是一线的高级治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Isolated Gastric Crohn's Disease.

Isolated gastric Crohn's Disease (IGCD) is a rare subset of Crohn's disease, poorly described in the literature. In this article, we present a 21-year-old man with gastric outlet obstruction secondary to IGCD. Management with Adalimumab and Upadacitinib failed, however he responded to Risankizumab. To our knowledge, this is the first case report documenting efficacy of Risankizumab in management of IGCD. In addition, we reviewed 13 published case reports describing IGCD. Ninety-two percent of cases were seen in women, typically presenting with nausea/vomiting and abdominal pain. Eighty-five percent of cases progressed to gastric outlet obstruction and tumor necrosis factor inhibitors were the first line advanced therapy.

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.