Asrita Vattikonda, Hasan Saleh, Ian Dryden, Maoyin Pang
{"title":"腺癌患者结肠切除术后肿瘤B细胞的偶然检测。","authors":"Asrita Vattikonda, Hasan Saleh, Ian Dryden, Maoyin Pang","doi":"10.14309/crj.0000000000001844","DOIUrl":null,"url":null,"abstract":"<p><p>Following a routine screening colonoscopy, a 54-year-old man underwent colon resection for adenocarcinoma, which revealed neoplastic B-cells in the lymph nodes surrounding the colon suggestive of chronic lymphocytic leukemia (CLL). Further evaluation identified a monoclonal B-cell population, and he was diagnosed with monoclonal B-cell lymphocytosis without meeting CLL diagnostic criteria. The patient had no clinical signs of leukemia and did not need acute treatment but was placed under annual surveillance. This case highlights the incidental discovery of neoplastic B-cells, emphasizing the importance of comprehensive histopathological evaluation and clinical correlation to guide management and monitoring for potential progression to CLL.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 10","pages":"e01844"},"PeriodicalIF":0.5000,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479105/pdf/","citationCount":"0","resultStr":"{\"title\":\"Incidental Detection of Neoplastic B Cells in the Colon Following Resection in a Patient With Adenocarcinoma.\",\"authors\":\"Asrita Vattikonda, Hasan Saleh, Ian Dryden, Maoyin Pang\",\"doi\":\"10.14309/crj.0000000000001844\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Following a routine screening colonoscopy, a 54-year-old man underwent colon resection for adenocarcinoma, which revealed neoplastic B-cells in the lymph nodes surrounding the colon suggestive of chronic lymphocytic leukemia (CLL). Further evaluation identified a monoclonal B-cell population, and he was diagnosed with monoclonal B-cell lymphocytosis without meeting CLL diagnostic criteria. The patient had no clinical signs of leukemia and did not need acute treatment but was placed under annual surveillance. This case highlights the incidental discovery of neoplastic B-cells, emphasizing the importance of comprehensive histopathological evaluation and clinical correlation to guide management and monitoring for potential progression to CLL.</p>\",\"PeriodicalId\":7394,\"journal\":{\"name\":\"ACG Case Reports Journal\",\"volume\":\"12 10\",\"pages\":\"e01844\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2025-09-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479105/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACG Case Reports Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14309/crj.0000000000001844\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/10/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACG Case Reports Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14309/crj.0000000000001844","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/10/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
Incidental Detection of Neoplastic B Cells in the Colon Following Resection in a Patient With Adenocarcinoma.
Following a routine screening colonoscopy, a 54-year-old man underwent colon resection for adenocarcinoma, which revealed neoplastic B-cells in the lymph nodes surrounding the colon suggestive of chronic lymphocytic leukemia (CLL). Further evaluation identified a monoclonal B-cell population, and he was diagnosed with monoclonal B-cell lymphocytosis without meeting CLL diagnostic criteria. The patient had no clinical signs of leukemia and did not need acute treatment but was placed under annual surveillance. This case highlights the incidental discovery of neoplastic B-cells, emphasizing the importance of comprehensive histopathological evaluation and clinical correlation to guide management and monitoring for potential progression to CLL.
期刊介绍:
ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.