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Safe Endoscopic Treatment for a Bleeding Infant With Multifocal Lymphangioendotheliomatosis and Thrombocytopenia (MLT). 多灶性淋巴管内皮瘤病合并血小板减少症出血婴儿的安全内镜治疗。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-27 eCollection Date: 2025-07-01 DOI: 10.14309/crj.0000000000001755
Or Steg Saban, Elena Pope, Govind B Chavhan, Manuel Carcao, Susanna Talarico, Simon C Ling
{"title":"Safe Endoscopic Treatment for a Bleeding Infant With Multifocal Lymphangioendotheliomatosis and Thrombocytopenia (MLT).","authors":"Or Steg Saban, Elena Pope, Govind B Chavhan, Manuel Carcao, Susanna Talarico, Simon C Ling","doi":"10.14309/crj.0000000000001755","DOIUrl":"10.14309/crj.0000000000001755","url":null,"abstract":"<p><p>We present the case of a 3-week-old girl with multiple cutaneous vascular lesions, melena, hematemesis, severe anemia (hemoglobin 4.4 g/dL), and thrombocytopenia (72 × 10<sup>3</sup>/µL), with clinical features consistent with multifocal lymphangioendotheliomatosis with thrombocytopenia (MLT). Upper gastrointestinal endoscopy revealed numerous actively bleeding angiomatous lesions, measuring 1-3 mm in diameter. Homeostasis was successfully achieved using argon plasma coagulation (APC). To our knowledge, this is among the few reports describing the effective use of APC in managing life-threatening gastric hemorrhage in an infant with MLT. While gastrointestinal perforation has been previously reported as a complication of endoscopic therapy in this context, our findings suggest that APC may be a viable option for refractory bleeding, provided that surgical support is immediately accessible.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01755"},"PeriodicalIF":0.6,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12204144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unraveled: Coil Migration After Embolization of Gastric Varices. 解开：胃静脉曲张栓塞后的线圈移动。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-27 eCollection Date: 2025-07-01 DOI: 10.14309/crj.0000000000001748
Sheel Patel, Dylan Flaherty, Nana Baah, Endashaw Omer
{"title":"Unraveled: Coil Migration After Embolization of Gastric Varices.","authors":"Sheel Patel, Dylan Flaherty, Nana Baah, Endashaw Omer","doi":"10.14309/crj.0000000000001748","DOIUrl":"10.14309/crj.0000000000001748","url":null,"abstract":"<p><p>Gastric varices are a severe complication of portal hypertension and may lead to life-threatening bleeding. Endovascular interventions, including transjugular intrahepatic portosystemic shunt and coil embolization, are effective treatment strategies. However, coil migration is a rare but serious complication. We present a unique case of coil migration from a gastric varix to the duodenum after transjugular intrahepatic portosystemic shunt and embolization.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01748"},"PeriodicalIF":0.6,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12204143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Upadacitinib for the Treatment of Upper Gastrointestinal Crohn's Disease. Upadacitinib治疗上消化道克罗恩病
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-27 eCollection Date: 2025-07-01 DOI: 10.14309/crj.0000000000001749
Bader AlBader, Rishi Jairath, Haneen Baitalmal, Talat Bessissow
{"title":"Upadacitinib for the Treatment of Upper Gastrointestinal Crohn's Disease.","authors":"Bader AlBader, Rishi Jairath, Haneen Baitalmal, Talat Bessissow","doi":"10.14309/crj.0000000000001749","DOIUrl":"10.14309/crj.0000000000001749","url":null,"abstract":"<p><p>Data on the use of antitumor necrosis factor therapy have shown some positive outcomes in case reports or small observational studies such as the data showing the benefit of adalimumab in this rare presentation of Crohn's disease. To our knowledge, there is no published data on the use of upadacitinib in the treatment of upper gastrointestinal Crohn's disease. We present a case report of a young patient with severe oral and esophageal Crohn's disease that was successfully treated with upadacitinib.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01749"},"PeriodicalIF":0.6,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12204142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144525978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intestinal Lymphangioma Presenting With Small Bowel Bleeding. 肠淋巴管瘤表现为小肠出血。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-26 eCollection Date: 2025-07-01 DOI: 10.14309/crj.0000000000001743
Fatma Mahmoud, Jenan Ghaith, Javed Raza, Pascale Anglade
{"title":"Intestinal Lymphangioma Presenting With Small Bowel Bleeding.","authors":"Fatma Mahmoud, Jenan Ghaith, Javed Raza, Pascale Anglade","doi":"10.14309/crj.0000000000001743","DOIUrl":"10.14309/crj.0000000000001743","url":null,"abstract":"<p><p>Obscure gastrointestinal bleeding poses a diagnostic challenge for gastroenterologists, though advancements such as video capsule endoscopy and enteroscopy have led to increased detection of small bowel lymphangiomas. Lymphangiomas are benign tumors with dilated lymphatic channels that rarely affect the jejunum or ileum. We present a rare case of jejunal lymphangioma causing obscure gastrointestinal bleeding diagnosed by video capsule endoscopy, confirmed by enteroscopy, and successfully treated with surgical resection.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01743"},"PeriodicalIF":0.6,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12200224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Diagnosis of Esophageal Lichen Planus: Recurrent Esophageal Strictures, Delayed-Onset Rash, and Tracheal Stenosis. 食管扁平苔藓的诊断：复发性食管狭窄、迟发性皮疹和气管狭窄。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-26 eCollection Date: 2025-07-01 DOI: 10.14309/crj.0000000000001744
Brian Gutermuth, Eric Shah, Linda Jiang
{"title":"The Diagnosis of Esophageal Lichen Planus: Recurrent Esophageal Strictures, Delayed-Onset Rash, and Tracheal Stenosis.","authors":"Brian Gutermuth, Eric Shah, Linda Jiang","doi":"10.14309/crj.0000000000001744","DOIUrl":"10.14309/crj.0000000000001744","url":null,"abstract":"<p><p>Lichen planus (LP) is a chronic inflammatory disorder involving the skin and mucous membranes. Esophageal LP is often under-recognized and may present with or without other mucocutaneous sites of involvement. Its diagnosis is made challenging by its variable presentation and high rate of negative biopsies. Although some studies have suggested diagnostic criteria and severity grading, no formal guidelines exist. Diagnosis is made with a combination of clinical presentation, macroscopic findings on endoscopy, and histologic evidence. This case report highlights the challenges in the diagnosis of biopsy-negative esophageal LP and importance of timely diagnosis and initiation of appropriate medical therapy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01744"},"PeriodicalIF":0.6,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12204140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cracking the Code: A Practical Guide to Publishing in the ACG Case Reports Journal. 破解密码：ACG案例报告期刊出版的实用指南。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-26 eCollection Date: 2025-07-01 DOI: 10.14309/crj.0000000000001747
Himesh B Zaver, Daniyal Abbas, Prateek S Harne
{"title":"Cracking the Code: A Practical Guide to Publishing in the ACG Case Reports Journal.","authors":"Himesh B Zaver, Daniyal Abbas, Prateek S Harne","doi":"10.14309/crj.0000000000001747","DOIUrl":"10.14309/crj.0000000000001747","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 7","pages":"e01747"},"PeriodicalIF":0.6,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12200211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Diagnosis of Granulomatosis With Polyangiitis Presenting With Oral Ulcerations, Ileitis, and Hematochezia. 肉芽肿病合并多血管炎的新诊断表现为口腔溃疡、回肠炎和便血。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-25 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001746
Stacey Rolak, Michael M Pham, Dora M Lam-Himlin, Mashal J Batheja
{"title":"New Diagnosis of Granulomatosis With Polyangiitis Presenting With Oral Ulcerations, Ileitis, and Hematochezia.","authors":"Stacey Rolak, Michael M Pham, Dora M Lam-Himlin, Mashal J Batheja","doi":"10.14309/crj.0000000000001746","DOIUrl":"10.14309/crj.0000000000001746","url":null,"abstract":"<p><p>Granulomatosis with polyangiitis (GPA) is a rare small vessel vasculitis that commonly presents with multiorgan involvement of the upper airways, lungs, and kidneys. We report a 55 year-old-man who presented with painful oral ulcers, diffuse joint pain, epistaxis, and intermittent maroon bowel movements. Infectious evaluation was unremarkable. Rheumatologic evaluation demonstrated elevated c-anti-neutrophil cytoplasmic antibody and proteinase 3 antibodies. Colonoscopy with terminal ileum biopsies demonstrated angiocentric inflammatory findings supportive of a diagnosis of GPA. This case was unusual in its presentation with predominately oral manifestations. A diagnosis of GPA should remain on the differential for patients with gastrointestinal bleeding, and these systemic symptoms require a high level of suspicion to lead to timely diagnosis.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01746"},"PeriodicalIF":0.6,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12189967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144493399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unusual Presentation of Gilbert Syndrome. 吉尔伯特综合征的一种不寻常的表现。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-20 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001741
Akhila Chilakala, Brenton G Davis, Max Goldman, Nizar A Mukhtar
{"title":"An Unusual Presentation of Gilbert Syndrome.","authors":"Akhila Chilakala, Brenton G Davis, Max Goldman, Nizar A Mukhtar","doi":"10.14309/crj.0000000000001741","DOIUrl":"10.14309/crj.0000000000001741","url":null,"abstract":"<p><p>Unconjugated hyperbilirubinemia arises from elevated bilirubin production, impaired hepatic uptake, or reduced bilirubin conjugation, the latter often attributed to hereditary factors such as Gilbert syndrome involving mutations in the diphosphoglucuronate-glucuronosyltransferase 1A1 gene. Bilirubin levels in Gilbert syndrome typically range from 1.2 to 3.0 mg/dL, occasionally peaking up to 5.0 mg/dL. This case report details a jaundiced 24-year-old man with no significant medical history but otherwise asymptomatic presenting with indirect hyperbilirubinemia markedly elevated to 10.3 mg/dL.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01741"},"PeriodicalIF":0.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malignancy Masquerade: Inclusion-Negative Herpes Simplex Virus Rectal Pseudotumor in a Patient With HIV. 恶性肿瘤假面具：包涵阴性的单纯疱疹病毒直肠假瘤在HIV患者。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-20 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001745
Aaron C Nguyen, Moez Karim Aziz, Frederick B Peng, Nathan Spezia-Lindner, Georgia Huffman, Stefanos Millas, Roberto Cavazos
{"title":"Malignancy Masquerade: Inclusion-Negative Herpes Simplex Virus Rectal Pseudotumor in a Patient With HIV.","authors":"Aaron C Nguyen, Moez Karim Aziz, Frederick B Peng, Nathan Spezia-Lindner, Georgia Huffman, Stefanos Millas, Roberto Cavazos","doi":"10.14309/crj.0000000000001745","DOIUrl":"10.14309/crj.0000000000001745","url":null,"abstract":"<p><p>Herpes simplex virus (HSV) infections are among the most common sexually transmitted infections in humans. However, atypical presentations may occur in immunocompromised patients such as nodules, condylomatous masses, or hypertrophic lesions. Even further, HSV pseudotumors with negative histologic staining have been incompletely discussed in previous literature. We present a 51-year-old patient with a history of well-controlled HIV-1, who presented with a rectal mass, originally concerning for underlying bacterial infection or malignancy. Despite negative HSV immunohistochemical staining on biopsy, the mass improved with empiric intravenous acyclovir therapy, ultimately suggestive of a rectal HSV pseudotumor.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01745"},"PeriodicalIF":0.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Periportal Paraganglioma: A Rare Cause of Obstructive Jaundice and Gastroesophageal Varices. 门静脉周围副神经节瘤：梗阻性黄疸和胃食管静脉曲张的罕见病因。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-20 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001742
Irhoboudu D Atogwe, Lefika Bathobakae, Fnu Deepali, Maria Lagarde Mussa, Olubunmi Shoyele
{"title":"Periportal Paraganglioma: A Rare Cause of Obstructive Jaundice and Gastroesophageal Varices.","authors":"Irhoboudu D Atogwe, Lefika Bathobakae, Fnu Deepali, Maria Lagarde Mussa, Olubunmi Shoyele","doi":"10.14309/crj.0000000000001742","DOIUrl":"10.14309/crj.0000000000001742","url":null,"abstract":"<p><p>Paragangliomas are rare neuroendocrine tumors arising from extra-adrenal chromaffin cells. Biliary tropism is exceptionally rare and can mimic primary biliary tract malignancies, thus presenting a diagnostic challenge. We describe a rare case of periportal paraganglioma presenting with obstructive jaundice and gastric and duodenal varices. Similar to other reported primary hepatic paragangliomas, this tumor was nonfunctioning, and there was no evidence of metastatic disease. The patient underwent portal vein stenting to relieve portal hypertension after failed laparoscopic resection because of high vascularity. He continues to follow-up with our clinic for serial blood tests and imaging and remains asymptomatic. This case highlights the importance of considering paraganglioma in the differential diagnosis of biliary tract masses.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01742"},"PeriodicalIF":0.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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