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An Unusual Case of Diffuse Large B-Cell Lymphoma of the Common Bile Duct. 胆总管弥漫性大b细胞淋巴瘤1例。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-05 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001734
Susanne Sonal, Hatem Kaseb
{"title":"An Unusual Case of Diffuse Large B-Cell Lymphoma of the Common Bile Duct.","authors":"Susanne Sonal, Hatem Kaseb","doi":"10.14309/crj.0000000000001734","DOIUrl":"10.14309/crj.0000000000001734","url":null,"abstract":"<p><p>Diffuse large B-cell lymphoma (DLBCL) of the common bile duct (CBD) is extremely rare. A 77-year-old male patient presented with obstructive jaundice, weight loss, and abdominal pain. An endoscopic retrograde cholangiography revealed a stricture in the common hepatic duct. Biopsy and cytology specimens performed were inconclusive. A pancreaticoduodenectomy revealed a final diagnosis of DLBCL of the CBD. DLBCL of the CBD usually presents with vague symptoms. The definitive diagnosis of DLBCL-CBD can only be rendered by immunomorphological assessment and based on careful exclusion of other nodal and extranodal sites.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01734"},"PeriodicalIF":0.6,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Refractory Diarrhea Related to EPHB4 Mutation in a Patient With Capillary Malformation-Arteriovenous Type 2 Syndrome. 2型毛细血管畸形动静脉综合征患者与EPHB4突变相关的难治性腹泻
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-04 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001707
Bridgette B McNally, Margaret C Liu, Tisha Lunsford, Jennifer Horsley-Silva, Karen Swanson, Thomas Byrne, Marcela Salomao, Maxwell Smith, Rosita Frazier
{"title":"Refractory Diarrhea Related to EPHB4 Mutation in a Patient With Capillary Malformation-Arteriovenous Type 2 Syndrome.","authors":"Bridgette B McNally, Margaret C Liu, Tisha Lunsford, Jennifer Horsley-Silva, Karen Swanson, Thomas Byrne, Marcela Salomao, Maxwell Smith, Rosita Frazier","doi":"10.14309/crj.0000000000001707","DOIUrl":"10.14309/crj.0000000000001707","url":null,"abstract":"<p><p>Capillary malformation-arteriovenous type 2 syndrome (CM-AVM2) is a rare, genetic vascular disorder associated with abnormal capillary malformations and arteriovenous malformations. We present a case of CM-AVM2 with refractory diarrhea and failure to thrive due to aberrant, telangiectatic capillaries, and subepithelial collagen deposition found throughout the GI tract on bidirectional endoscopy. The patient was recalcitrant to standard therapies, so bevacizumab was trialed, but the patient expired. This is the first case of CM-AVM2 with diffuse GI mucosal involvement resulting in malabsorption. There is no treatment for this pathology, but treatment with bevacizumab or a mammalian target of rapamycin inhibitor may be efficacious.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01707"},"PeriodicalIF":0.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144223994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Esophageal Granular Cell Tumor Associated With Eosinophilic Gastrointestinal Disease. 食管颗粒细胞瘤与嗜酸性胃肠道疾病相关。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-06-04 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001720
Cathy Zheng, Robert Mowery, Sareena Ali, Camilla Allen, Ryan T Hoff
{"title":"Esophageal Granular Cell Tumor Associated With Eosinophilic Gastrointestinal Disease.","authors":"Cathy Zheng, Robert Mowery, Sareena Ali, Camilla Allen, Ryan T Hoff","doi":"10.14309/crj.0000000000001720","DOIUrl":"10.14309/crj.0000000000001720","url":null,"abstract":"<p><p>Granular cell tumors (GCTs) are typically benign lesions that can occur in the gastrointestinal tract. Eosinophilic gastrointestinal disease, including eosinophilic esophagitis (EoE), is an immune-mediated condition characterized by eosinophil-predominant inflammation in the gastrointestinal tract. We review previously reported cases of EoE associated with GCTs. To our knowledge, we present the first case of esophageal GCT in a patient with a long history of eosinophilic gastrointestinal disease and likely several years of active EoE before esophageal GCT diagnosis.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01720"},"PeriodicalIF":0.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12136658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144223993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of Autoimmune Enteropathy With Vedolizumab. Vedolizumab治疗自身免疫性肠病
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-30 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001716
Tara Alleyasin, Evan Wilder, Warren Reidel, Emma Du, Quan M Nhu
{"title":"Treatment of Autoimmune Enteropathy With Vedolizumab.","authors":"Tara Alleyasin, Evan Wilder, Warren Reidel, Emma Du, Quan M Nhu","doi":"10.14309/crj.0000000000001716","DOIUrl":"10.14309/crj.0000000000001716","url":null,"abstract":"<p><p>Autoimmune enteropathy (AIE) is a rare condition characterized by immune-mediated villous atrophy with associated chronic diarrhea. In this case, a 34-year-old man with AIE was treated with vedolizumab, an anti-ɑ4b7 integrin that inhibits intestinal lymphocyte trafficking, after initial treatments with prednisone, open-capsule budesonide, azathioprine, infliximab, and adalimumab showed minimal response. Vedolizumab resulted in moderate symptomatic and histological improvement but was discontinued due to possible drug-induced liver injury. This case suggests the potential therapeutic efficacy of vedolizumab in treating AIE, though more research is needed.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01716"},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic Management of an Acute Postsurgical Fluid Collection. 急性术后积液的内镜处理。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-30 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001725
Mohamed Karam Douedari, Neil Chokshi, Rama Tarakji, Manuel Berzosa
{"title":"Endoscopic Management of an Acute Postsurgical Fluid Collection.","authors":"Mohamed Karam Douedari, Neil Chokshi, Rama Tarakji, Manuel Berzosa","doi":"10.14309/crj.0000000000001725","DOIUrl":"10.14309/crj.0000000000001725","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01725"},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic Predisposition and Multifocal Cancer: A Complex Case of Lynch Syndrome. 遗传易感性和多灶性癌症：Lynch综合征的一个复杂病例。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-30 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001718
Caleb Glover, Claire Russell, Ali Rida, Shweta Bhatnagar, Edward Cay, Eric Nguyen, Alexandra Davies, Albert Ross
{"title":"Genetic Predisposition and Multifocal Cancer: A Complex Case of Lynch Syndrome.","authors":"Caleb Glover, Claire Russell, Ali Rida, Shweta Bhatnagar, Edward Cay, Eric Nguyen, Alexandra Davies, Albert Ross","doi":"10.14309/crj.0000000000001718","DOIUrl":"10.14309/crj.0000000000001718","url":null,"abstract":"<p><p>This case report describes the complex presentation and management of a 35-year-old man with synchronous malignancies: A well-differentiated grade 2 neuroendocrine tumor of the pancreas metastasized to the liver and bone, and invasive adenocarcinoma of the sigmoid colon. Strong clinical suspicion for Lynch syndrome arose due to the patient's family history and the loss of MSH1 and PMS2 protein expression in the colon adenocarcinoma. The patient presented with hypoglycemia, abdominal pain, and diarrhea. A multidisciplinary approach confirmed the diagnoses, including imaging studies (computed tomography, magnetic resonance imaging), biopsies, and immunohistochemistry; treatment involved endocrine management for hypoglycemia, planned surgical intervention (distal pancreatectomy, splenectomy, hepatic ablation), and consideration of systemic chemotherapy. Genetic testing for Lynch syndrome was initiated to guide long-term management and family screening. This case highlights the diagnostic and therapeutic challenges of managing multiple synchronous cancers, the importance of considering hereditary cancer syndromes, and the necessity of a coordinated multidisciplinary approach for optimal patient outcomes.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01718"},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Innovative Application of a Rigidizing Overtube in Endoscopic Ultrasound-Guided Biopsy for Sampling of a Cecal Submucosal Lesion. 超声内镜引导下盲肠粘膜下病变活检中刚性覆盖管的创新应用。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-30 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001722
Anas Zaher, Nicholas G Brown
{"title":"Innovative Application of a Rigidizing Overtube in Endoscopic Ultrasound-Guided Biopsy for Sampling of a Cecal Submucosal Lesion.","authors":"Anas Zaher, Nicholas G Brown","doi":"10.14309/crj.0000000000001722","DOIUrl":"10.14309/crj.0000000000001722","url":null,"abstract":"<p><p>Subepithelial lesions in the gastrointestinal tract present diagnostic challenges, particularly in difficult-to-access regions like the cecum. This case report describes a 71-year-old woman with a submucosal lesion adjacent to the appendix, where a rigidizing overtube was used to stabilize the colonoscope for an endoscopic ultrasound-guided fine-needle biopsy. The procedure was successful, obtaining a benign diagnosis without the need for surgery. This case highlights the utility of rigidizing overtube technology in enhancing the accuracy and safety of endoscopic interventions for subepithelial lesions, particularly in anatomically challenging locations like the cecum.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01722"},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatic Schistosomiasis Presenting as a Hepatic Mass. 肝脏血吸虫病表现为肝脏肿块。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-30 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001724
Jin Yun, Jian Shen, Udip Dahal, Ken Flora
{"title":"Hepatic Schistosomiasis Presenting as a Hepatic Mass.","authors":"Jin Yun, Jian Shen, Udip Dahal, Ken Flora","doi":"10.14309/crj.0000000000001724","DOIUrl":"10.14309/crj.0000000000001724","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01724"},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Peroral Endoscopic Myotomy Leak With an Esophageal Fully Covered Self-Expandable Metal Stents. 经口内窥镜下肌切开术漏用食管全覆盖自扩张金属支架治疗。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-30 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001719
Mohamed Elbayoumy, Nouf K Alalshaikh, Renad Fayez Alharthy, Manhal Aldaher, Abdullah T Alwazna
{"title":"Management of Peroral Endoscopic Myotomy Leak With an Esophageal Fully Covered Self-Expandable Metal Stents.","authors":"Mohamed Elbayoumy, Nouf K Alalshaikh, Renad Fayez Alharthy, Manhal Aldaher, Abdullah T Alwazna","doi":"10.14309/crj.0000000000001719","DOIUrl":"10.14309/crj.0000000000001719","url":null,"abstract":"<p><p>Achalasia type II is a rare esophageal motility disorder characterized by impaired relaxation of the lower esophageal sphincter. Peroral endoscopic myotomy (POEM) is a safe and minimally invasive procedure for achalasia. Although rare, complications such as esophageal perforation and pleural effusion can arise. This case study presents a 69-year-old woman with achalasia type II who developed esophageal perforation and empyema after POEM. Initial management with hemostatic clips was insufficient due to stent migration, necessitating a 135-mm fully covered self-expandable metal stent. Due to persistent leakage due to stent migration, a mega stent was ultimately placed, successfully sealing the esophageal leak. This report highlights the efficacy of mega stents as a viable option for managing recurrent esophageal leaks and complications post-POEM, especially in cases where stent migration complicates traditional approaches.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01719"},"PeriodicalIF":0.6,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Pancreatitis Caused by Hemobilia: An Unusual Complication of Laparoscopic Cholecystectomy in a Patient With History of ROUX-EN-Y Gastric Bypass. 胆道出血引起的急性胰腺炎：有ROUX-EN-Y胃旁路手术史患者腹腔镜胆囊切除术的一种罕见并发症。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-05-24 eCollection Date: 2025-06-01 DOI: 10.14309/crj.0000000000001721
Adily N Elmi, Sami Mesgun, Arthur R Baluyut
{"title":"Acute Pancreatitis Caused by Hemobilia: An Unusual Complication of Laparoscopic Cholecystectomy in a Patient With History of ROUX-EN-Y Gastric Bypass.","authors":"Adily N Elmi, Sami Mesgun, Arthur R Baluyut","doi":"10.14309/crj.0000000000001721","DOIUrl":"10.14309/crj.0000000000001721","url":null,"abstract":"<p><p>Acute pancreatitis as a result of hemobilia after laparoscopic cholecystectomy is a rare vascular complication with a challenging clinical diagnosis and treatment approach not eminent or available. We are reporting the fourth case of acute pancreatitis after laparoscopic cholecystectomy caused by hemobilia secondary to a right hepatic artery pseudoaneurysm. To our knowledge, this is the first such case reported in the United States.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 6","pages":"e01721"},"PeriodicalIF":0.6,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12106223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144172404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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