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Crohn's Disease Discovery to Modern Treatment: A Gastroenterology Fellow's Experience at Mount Sinai With the Crohn's & Colitis Foundation Visiting Fellowship Program. 从发现克罗恩病到现代治疗：西奈山克罗恩氏症和结肠炎基金会访问学者项目胃肠病学研究员的经历。
IF 0.6
ACG Case Reports Journal Pub Date : 2024-10-10 eCollection Date: 2024-10-01 DOI: 10.14309/crj.0000000000001533
Robert James Pattison, Arafa Djalal
{"title":"Crohn's Disease Discovery to Modern Treatment: A Gastroenterology Fellow's Experience at Mount Sinai With the Crohn's & Colitis Foundation Visiting Fellowship Program.","authors":"Robert James Pattison, Arafa Djalal","doi":"10.14309/crj.0000000000001533","DOIUrl":"10.14309/crj.0000000000001533","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 10","pages":"e01533"},"PeriodicalIF":0.6,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enteropathy-Associated T-Cell Lymphoma Treated With Autologous Hematopoietic Stem-Cell Transplant: A Glimmer of Hope? 自体造血干细胞移植治疗肠病相关 T 细胞淋巴瘤：一线希望？
IF 0.6
ACG Case Reports Journal Pub Date : 2024-10-10 eCollection Date: 2024-10-01 DOI: 10.14309/crj.0000000000001529
Amrit Gahra, Anudeep Katrevula, Anuradha Sekaran, Balasaheb Wanve, Goutham Reddy Katukuri, Sundeep Lakhtakia, Nageshwar Reddy Duvvur
{"title":"Enteropathy-Associated T-Cell Lymphoma Treated With Autologous Hematopoietic Stem-Cell Transplant: A Glimmer of Hope?","authors":"Amrit Gahra, Anudeep Katrevula, Anuradha Sekaran, Balasaheb Wanve, Goutham Reddy Katukuri, Sundeep Lakhtakia, Nageshwar Reddy Duvvur","doi":"10.14309/crj.0000000000001529","DOIUrl":"10.14309/crj.0000000000001529","url":null,"abstract":"<p><p>We report a case of primary enteropathy-associated T-cell lymphoma in a 50-year-old man presenting with abdominal pain, chronic diarrhea, and significant weight loss over 6 months. Diagnosis was confirmed through endoscopy, biopsy, and positron emission tomography-computed tomography, staging the disease as stage 1E. The patient underwent initial treatment with the cyclophosphamide, doxorubicin (also known as hydroxydaunorubicin), vincristine (also known as oncovin), etoposide, and prednisolone chemotherapy regimen, followed by high-dose hyper-fractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone chemotherapy and autologous stem cell transplantation. Despite developing febrile neutropenia and septic shock during treatment, the patient achieved disease remission and symptom resolution. This case underscores the potential of autologous stem-cell transplantation as a curative approach for primary enteropathy-associated T-cell lymphoma and highlights the need for further research on its effectiveness.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 10","pages":"e01529"},"PeriodicalIF":0.6,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined Heart and Liver Transplantation in Delayed-Onset Propionic Acidemia. 迟发性丙酸血症患者的心肝联合移植手术
IF 0.6
ACG Case Reports Journal Pub Date : 2024-10-10 eCollection Date: 2024-10-01 DOI: 10.14309/crj.0000000000001526
Mattie K White, Omar T Sims, Jason Eng, Jamak Modaresi Esfeh
{"title":"Combined Heart and Liver Transplantation in Delayed-Onset Propionic Acidemia.","authors":"Mattie K White, Omar T Sims, Jason Eng, Jamak Modaresi Esfeh","doi":"10.14309/crj.0000000000001526","DOIUrl":"10.14309/crj.0000000000001526","url":null,"abstract":"<p><p>Amish patients with propionic acidemia can have delayed presentations with rapid onset, severe cardiac decompensation despite metabolic control. Medical management is limited to strict low protein diet and correction of underlying catabolic triggers. Liver transplantation is indicated in pediatric patients with recurrent metabolic decompensation. There are limited reports of pediatric combined liver and heart transplantation. We present the first case of combined liver and heart transplantation in an Amish adult with newly diagnosed propionic acidemia and severe nonischemic dilated cardiomyopathy on advanced cardiac life support. Special considerations were necessary for close metabolic status monitoring and prevention of catabolic states.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 10","pages":"e01526"},"PeriodicalIF":0.6,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolated Acute Liver Injury Following Mass Envenomation by Wasps. 黄蜂大规模啮食后的孤立性急性肝损伤
IF 0.6
ACG Case Reports Journal Pub Date : 2024-10-10 eCollection Date: 2024-10-01 DOI: 10.14309/crj.0000000000001534
Hayneil Solanki, Tara Fox, Jerry Chin
{"title":"Isolated Acute Liver Injury Following Mass Envenomation by Wasps.","authors":"Hayneil Solanki, Tara Fox, Jerry Chin","doi":"10.14309/crj.0000000000001534","DOIUrl":"10.14309/crj.0000000000001534","url":null,"abstract":"<p><p>Acute liver injury from wasp venom exposure has been reported in the literature, most often in the context of anaphylaxis and multiorgan injury. We present a case of isolated liver injury, a rare presentation, in a healthy 26-year-old man stung by more than 40 wasps. We observed a delayed presentation with conjugated hyperbilirubinemia, significantly raised transaminases, and mild coagulopathy, in the absence of other organ involvement. Complete normalization of liver enzymes was seen 61 days following presentation. Clinicians encountering patients with liver injury in the context of wasp stings should consider wasp venom-associated hepatitis as a possible cause.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 10","pages":"e01534"},"PeriodicalIF":0.6,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Tirzepatide-Induced Hepatotoxicity. 一个罕见的地西泮诱发肝中毒病例
IF 0.6
ACG Case Reports Journal Pub Date : 2024-10-04 eCollection Date: 2024-10-01 DOI: 10.14309/crj.0000000000001484
Aalam Sohal, Luis Casanova, Kris V Kowdley
{"title":"A Rare Case of Tirzepatide-Induced Hepatotoxicity.","authors":"Aalam Sohal, Luis Casanova, Kris V Kowdley","doi":"10.14309/crj.0000000000001484","DOIUrl":"10.14309/crj.0000000000001484","url":null,"abstract":"<p><p>Tirzepatide is the first dual incretin glucose-dependent insulinotropic polypeptide/glucagon-like peptide 1 receptor activator approved for the management of type II diabetes mellitus. This drug was also recently approved by the Food and Drug Administration as a management option for patients with obesity. Tirzepatide has been also reported to be beneficial in reducing liver fat content. Although its efficacy is well described in the literature, no cases of tirzepatide-induced hepatotoxicity have been reported. We report a case of a 37-year-old woman with metabolic syndrome who was noted to have elevated liver enzymes secondary to tirzepatide use.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 10","pages":"e01484"},"PeriodicalIF":0.6,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11452087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142379878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Liver Failure Induced by Provitalize: A Menopause Supplement Concocted From Herbs & Probiotics. Provitalize诱发急性肝衰竭：一种由草药和益生菌制成的更年期补充剂。
IF 0.6
ACG Case Reports Journal Pub Date : 2024-09-20 eCollection Date: 2024-09-01 DOI: 10.14309/crj.0000000000001509
Rahul Patel, Ahmed Hassan, Hayle Scanlan, Matthew Everwine, Zhiyong Ren, Charles Snyder, Hisham ElGenaidi
{"title":"Acute Liver Failure Induced by Provitalize: A Menopause Supplement Concocted From Herbs & Probiotics.","authors":"Rahul Patel, Ahmed Hassan, Hayle Scanlan, Matthew Everwine, Zhiyong Ren, Charles Snyder, Hisham ElGenaidi","doi":"10.14309/crj.0000000000001509","DOIUrl":"10.14309/crj.0000000000001509","url":null,"abstract":"<p><p>Drug-induced liver injury is one of the most common causes of acute liver failure in the Western world. Despite discontinuation of the offending agent, it can still tax a grim prognosis. We describe a case of a menopausal woman taking a herbal supplement called \"Provitalize\" to relieve hot flashes and bloating. This is the first case report of liver injury from this supplement. She initially presented with mild jaundice and elevated transaminases. Unfortunately, she rapidly progressed to encephalopathy, experienced multiorgan failure, and then died.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01509"},"PeriodicalIF":0.6,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11415125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coil Embolization of a Portosystemic Shunt Presenting as a Varicocele. 对表现为精索静脉曲张的门静脉分流进行线圈栓塞。
IF 0.6
ACG Case Reports Journal Pub Date : 2024-09-20 eCollection Date: 2024-09-01 DOI: 10.14309/crj.0000000000001218
Vincent Galate, Ian Kozlowski, Carmen Vogt, Ryan Ash, Adam Alli, Aaron Rohr
{"title":"Coil Embolization of a Portosystemic Shunt Presenting as a Varicocele.","authors":"Vincent Galate, Ian Kozlowski, Carmen Vogt, Ryan Ash, Adam Alli, Aaron Rohr","doi":"10.14309/crj.0000000000001218","DOIUrl":"https://doi.org/10.14309/crj.0000000000001218","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01218"},"PeriodicalIF":0.6,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11415081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic Retrieval of a Metallic Cross in a Patient With Acute Psychosis and Religious Delusions. 在一名患有急性精神病和宗教妄想症的患者身上通过内窥镜取出金属十字架。
IF 0.6
ACG Case Reports Journal Pub Date : 2024-09-20 eCollection Date: 2024-09-01 DOI: 10.14309/crj.0000000000001501
Jordan Malone, Robinder Abrol, Jose Aguirre
{"title":"Endoscopic Retrieval of a Metallic Cross in a Patient With Acute Psychosis and Religious Delusions.","authors":"Jordan Malone, Robinder Abrol, Jose Aguirre","doi":"10.14309/crj.0000000000001501","DOIUrl":"10.14309/crj.0000000000001501","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01501"},"PeriodicalIF":0.6,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11415084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Evasive Liver Mass in a Human Immunodeficiency Virus (HIV)-Positive Patient. 一名人类免疫缺陷病毒 (HIV) 阳性患者的肝脏肿块。
IF 0.6
ACG Case Reports Journal Pub Date : 2024-09-20 eCollection Date: 2024-09-01 DOI: 10.14309/crj.0000000000001481
Reanay Berezovskiy, James M Crawford, Arvind Rishi, Sohil Khurana, Joshua Kern, Stefani Morscher, Sanjaya K Satapathy
{"title":"An Evasive Liver Mass in a Human Immunodeficiency Virus (HIV)-Positive Patient.","authors":"Reanay Berezovskiy, James M Crawford, Arvind Rishi, Sohil Khurana, Joshua Kern, Stefani Morscher, Sanjaya K Satapathy","doi":"10.14309/crj.0000000000001481","DOIUrl":"10.14309/crj.0000000000001481","url":null,"abstract":"<p><p>IgG4-related disease (IgG4-RD) is an autoimmune syndrome that is characterized by elevated levels of serum IgG4 and infiltration of various tissue types by IgG4 immunoreactive plasma cells. The IgG4-RD can result in systemic disease and the formation of inflammatory mass lesions, frequently addressed as pseudotumors. While IgG4-RD can manifest in various organs, liver involvement is rare, and because it is an immune-mediated inflammatory process, it is uncommon in patients who are immunocompromised. Furthermore, despite IgG4-RD responding well to immunosuppressive treatment, cases of spontaneous remission are exceedingly rare in the literature. In this report, we present the unique case of a self-resolving IgG4-RD lesion of the liver in a HIV positive patient.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01481"},"PeriodicalIF":0.6,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11415121/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intestinal Ultrasound: Envisioning a New Future for Crohn's Disease Management. 肠道超声波：展望克罗恩病治疗的新未来。
IF 0.6
ACG Case Reports Journal Pub Date : 2024-09-19 eCollection Date: 2024-09-01 DOI: 10.14309/crj.0000000000001511
Amrik Randhawa, Tom Guzowski
{"title":"Intestinal Ultrasound: Envisioning a New Future for Crohn's Disease Management.","authors":"Amrik Randhawa, Tom Guzowski","doi":"10.14309/crj.0000000000001511","DOIUrl":"https://doi.org/10.14309/crj.0000000000001511","url":null,"abstract":"<p><p>The use of intestinal ultrasound (IUS) in the clinical assessment of intestinal disorders remains in its infancy in North America. We present a case in which IUS was used as a complement to Crohn's disease treatment in a 19-year-old man. After endoscopy and diagnosis, IUS was employed alongside other investigations to elucidate the extent of disease activity. It allowed identification and monitoring of complications such as free fluid and mucosal inflammation. IUS provided a marker of disease activity, even during apparent clinical remission. This case demonstrates that IUS can enhance disease monitoring and inform direction of therapy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"11 9","pages":"e01511"},"PeriodicalIF":0.6,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11412704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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