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Unicentric Castleman Disease Coexisting With Type 2 Autoimmune Pancreatitis: A Case Report Mimicking Pancreatic Cancer and Near-Whipple Surgery. 单中心Castleman病合并2型自身免疫性胰腺炎：一例模拟胰腺癌和近惠普尔手术
IF 0.6
ACG Case Reports Journal Pub Date : 2025-03-03 eCollection Date: 2025-03-01 DOI: 10.14309/crj.0000000000001635
Joel Gabin Konlack Mekontso, Akil Olliverrie, Jingwei Ren, Veronika Stefanishina, Syed Karim, Shahbaz Khan, Thomas McIntyre, Mohammad Choudhry
{"title":"Unicentric Castleman Disease Coexisting With Type 2 Autoimmune Pancreatitis: A Case Report Mimicking Pancreatic Cancer and Near-Whipple Surgery.","authors":"Joel Gabin Konlack Mekontso, Akil Olliverrie, Jingwei Ren, Veronika Stefanishina, Syed Karim, Shahbaz Khan, Thomas McIntyre, Mohammad Choudhry","doi":"10.14309/crj.0000000000001635","DOIUrl":"10.14309/crj.0000000000001635","url":null,"abstract":"<p><p>This case describes a 46-year-old man presenting with epigastric pain, weight loss, and obstructive jaundice, initially misdiagnosed as pancreatic cancer due to a pancreatic head mass compressing the common bile duct. Intraoperative biopsies during an aborted Whipple procedure revealed coexisting autoimmune pancreatitis and Castleman disease. This case highlights the diagnostic challenges of Castleman disease, its potential association with autoimmune pancreatitis, and the critical role of histological analysis in differentiating it from malignancy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01635"},"PeriodicalIF":0.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11878988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unexpected Discovery at Resection Site: Plasmablastic Lymphoma After Polypectomy. 切除部位意外发现：息肉切除术后浆母细胞淋巴瘤。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-02-27 eCollection Date: 2025-03-01 DOI: 10.14309/crj.0000000000001633
Ryan Njeim, Mohammad Abureesh, Yashna Singh, Youssef El Douaihy
{"title":"Unexpected Discovery at Resection Site: Plasmablastic Lymphoma After Polypectomy.","authors":"Ryan Njeim, Mohammad Abureesh, Yashna Singh, Youssef El Douaihy","doi":"10.14309/crj.0000000000001633","DOIUrl":"https://doi.org/10.14309/crj.0000000000001633","url":null,"abstract":"<p><p>Plasmablastic lymphoma (PBL) is a rare, aggressive subtype of diffuse large B-cell lymphoma that has usually been associated with human immunodeficiency virus and Ebstein-Barr virus infections. Commonly seen in the oral cavity, it can affect any part of the gastrointestinal tract. This report describes a unique case of PBL that appeared in an 81-year-old immunocompetent patient. During an initial colonoscopy, a 2-cm polyp in the distal transverse colon was removed via full-thickness resection with pathology showing tubular adenoma with foci of high-grade dysplasia. After 7 months, a repeat colonoscopy found a 3-cm sessile polyp at the site of resection, which, after removal, was found to be a PBL. This is the first case described in the literature regarding the growth of PBL after full-thickness resection of a tubular adenoma in such a short interval.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01633"},"PeriodicalIF":0.6,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11868435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143539757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Pelvic Mass in a Young Patient With Crohn's Disease. 一名年轻克罗恩病患者的盆腔肿块
IF 0.6
ACG Case Reports Journal Pub Date : 2025-02-26 eCollection Date: 2025-03-01 DOI: 10.14309/crj.0000000000001627
Charles D Evers, Aishwarya Ravindran, Frida Rosenblum, Frederick Weber
{"title":"A Pelvic Mass in a Young Patient With Crohn's Disease.","authors":"Charles D Evers, Aishwarya Ravindran, Frida Rosenblum, Frederick Weber","doi":"10.14309/crj.0000000000001627","DOIUrl":"10.14309/crj.0000000000001627","url":null,"abstract":"<p><p>Castleman disease (CD) is a rare group of lymphoproliferative disorders subdivided based on clinical features. Although not fully understood, the pathogenesis of both CD and Crohn's disease involves a combination of immune dysregulation and infectious and environmental factors. Interleukin-6, a proinflammatory cytokine, is associated with both diseases and can serve as a common therapeutic target in CD. We report a rare case of coexisting unicentric Castleman disease in a young patient with Crohn's disease.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01627"},"PeriodicalIF":0.6,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Esophageal Pseudodiverticulosis Associated With Cytomegalovirus Esophagitis Presenting With Severe Upper Gastrointestinal Bleeding. 一例罕见的食管假性憩室伴巨细胞病毒食管炎病例，表现为严重的上消化道出血。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-02-26 eCollection Date: 2025-03-01 DOI: 10.14309/crj.0000000000001636
Khushbu Patel, Jenny Jan, Brooke Glessing, Gregory Cooper
{"title":"A Rare Case of Esophageal Pseudodiverticulosis Associated With Cytomegalovirus Esophagitis Presenting With Severe Upper Gastrointestinal Bleeding.","authors":"Khushbu Patel, Jenny Jan, Brooke Glessing, Gregory Cooper","doi":"10.14309/crj.0000000000001636","DOIUrl":"10.14309/crj.0000000000001636","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01636"},"PeriodicalIF":0.6,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unveiling the Genetic Culprit: A Diagnostic Dilemma of Recurrent Cholestasis With Intrahepatic Stones. 揭示遗传罪魁祸首：复发性胆汁淤积伴肝内结石的诊断困境。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-02-26 eCollection Date: 2025-03-01 DOI: 10.14309/crj.0000000000001624
Jacob A Ciricillo, Farrah Rahim, Yeshika Sharma
{"title":"Unveiling the Genetic Culprit: A Diagnostic Dilemma of Recurrent Cholestasis With Intrahepatic Stones.","authors":"Jacob A Ciricillo, Farrah Rahim, Yeshika Sharma","doi":"10.14309/crj.0000000000001624","DOIUrl":"10.14309/crj.0000000000001624","url":null,"abstract":"<p><p>Recurrent cholestasis poses diagnostic challenges and necessitates repeated testing. The <i>ABCB4</i> (adenosine triphosphate-binding cassette, subfamily B, member 4) gene encodes a protein that removes phospholipids from the hepatic canalicular membrane through bile salts. Mutations lead to a spectrum of clinical syndromes that cause recurrent cholestasis, pruritus, and jaundice. This case follows a young female with recurrent cholestasis postcholecystectomy, intrahepatic stones on endoscopic retrograde cholangiopancreatography, and repeated intrahepatic cholestasis of pregnancy. Phenotypes of <i>ABCB4</i> mutations should be considered when facing cholestasis of unclear etiology. Early genetic testing and ursodeoxycholic acid treatment may prevent progression toward hepatic fibrosis and end-stage liver disease.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01624"},"PeriodicalIF":0.6,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extensive Esophageal Papillomatosis: A Rare Disease With Difficult Diagnosis. 广泛的食管乳头状瘤病：一种罕见且难以诊断的疾病。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-02-26 eCollection Date: 2025-03-01 DOI: 10.14309/crj.0000000000001638
Miriam Chinzon, Sergio Barbosa Marques, Eduardo Guimarães Hourneaux de Moura
{"title":"Extensive Esophageal Papillomatosis: A Rare Disease With Difficult Diagnosis.","authors":"Miriam Chinzon, Sergio Barbosa Marques, Eduardo Guimarães Hourneaux de Moura","doi":"10.14309/crj.0000000000001638","DOIUrl":"10.14309/crj.0000000000001638","url":null,"abstract":"<p><p>Extensive esophageal papillomatosis is a rare condition with uncertain pathophysiology. We present a case involving a 78-year-old woman, with no notable habits or addictions, who presented with dysphagia and weight loss. She was diagnosed with extensive esophageal papillomatosis, causing esophageal substenosis. Diagnosis of dysplasia in such cases are challenging, and management of the risk of malignant transformation remains uncertain.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 3","pages":"e01638"},"PeriodicalIF":0.6,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practical Considerations and Ethical Implications of Using Artificial Intelligence in Writing Scientific Manuscripts. 使用人工智能撰写科学稿件的实际考虑和伦理意义。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-02-19 eCollection Date: 2025-02-01 DOI: 10.14309/crj.0000000000001629
Muhammad Nadeem Yousaf
{"title":"Practical Considerations and Ethical Implications of Using Artificial Intelligence in Writing Scientific Manuscripts.","authors":"Muhammad Nadeem Yousaf","doi":"10.14309/crj.0000000000001629","DOIUrl":"10.14309/crj.0000000000001629","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 2","pages":"e01629"},"PeriodicalIF":0.6,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11838153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143456594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pancreatitis, Polyarthritis and Panniculitis (PPP) Syndrome - A Rare Presentation. 胰腺炎，多发性关节炎和胰膜炎（PPP）综合征-一种罕见的表现。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-02-17 eCollection Date: 2025-02-01 DOI: 10.14309/crj.0000000000001601
Devank Shah, Rupesh Pokharna, Sudhir Maharshi, Kamleshkumar Sharma, Prerak Maniar
{"title":"Pancreatitis, Polyarthritis and Panniculitis (PPP) Syndrome - A Rare Presentation.","authors":"Devank Shah, Rupesh Pokharna, Sudhir Maharshi, Kamleshkumar Sharma, Prerak Maniar","doi":"10.14309/crj.0000000000001601","DOIUrl":"10.14309/crj.0000000000001601","url":null,"abstract":"<p><p>Pancreatitis, panniculitis, and polyarthritis (PPP) syndrome is a rare manifestation (prevalence 2%-3%) of underlying pancreatic pathology which is characterized by fat necrosis in subcutaneous tissue and joints. The widely accepted etiological hypothesis is systemic dissemination of pancreatic lipase. It has a mortality rate approaching 25%. We present a case of pancreatitis, panniculitis, and polyarthritis syndrome in a 52-year-old man with chronic pancreatitis complicated by pancreatico-pericardial fistula.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 2","pages":"e01601"},"PeriodicalIF":0.6,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835122/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid Resolution of Perianal Crohn's Disease with Upadacitinib. Upadacitinib快速治疗肛周克罗恩病。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-02-15 eCollection Date: 2025-02-01 DOI: 10.14309/crj.0000000000001623
Kristen Brennan, Poonam Beniwal-Patel
{"title":"Rapid Resolution of Perianal Crohn's Disease with Upadacitinib.","authors":"Kristen Brennan, Poonam Beniwal-Patel","doi":"10.14309/crj.0000000000001623","DOIUrl":"10.14309/crj.0000000000001623","url":null,"abstract":"<p><p>A 20-year-old woman with ileocolonic, stricturing, and penetrating Crohn's disease (CD) presented with new onset perianal and vulvar CD despite having a diverting ileostomy and medical therapy with ustekinumab. She had previous secondary nonresponse to infliximab, vedolizumab, and adalimumab. There is a paucity of data supporting the use of medical therapies for perianal CD. Upadacitinib is approved for treatment of moderate to severely active ulcerative colitis and CD. This case demonstrates successful and rapid resolution of perianal CD within weeks of initiating upadacitinib.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 2","pages":"e01623"},"PeriodicalIF":0.6,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Pancreatitis Puzzle: Antimelanoma Differentiation-Associated Gene-5 Dermatomyositis Unveiled. 胰腺炎之谜：抗黑色素瘤分化相关基因-5皮肌炎揭晓。
IF 0.6
ACG Case Reports Journal Pub Date : 2025-02-15 eCollection Date: 2025-02-01 DOI: 10.14309/crj.0000000000001621
Eaman Alhassan, Katherine Ruddy, Stratos Christianakis, Leanna Wise
{"title":"The Pancreatitis Puzzle: Antimelanoma Differentiation-Associated Gene-5 Dermatomyositis Unveiled.","authors":"Eaman Alhassan, Katherine Ruddy, Stratos Christianakis, Leanna Wise","doi":"10.14309/crj.0000000000001621","DOIUrl":"10.14309/crj.0000000000001621","url":null,"abstract":"<p><p>Antimelanoma differentiation-associated gene (MDA)-5 dermatomyositis, a subtype of inflammatory myopathy, is associated with interstitial lung disease and distinctive skin findings. We report a 39-year-old woman presenting with pancreatitis as the first presentation of anti-MDA-5 dermatomyositis. The patient had no pancreatitis risk factors, and her muscle enzymes were normal. Months later, she developed characteristic skin lesions, leading to the diagnosis of anti-MDA-5 dermatomyositis. This case emphasizes the need to recognize key skin lesions, such as ulcers, palmar, and kissing papules while maintaining a broad differential to identify atypical presentations such as pancreatitis, which can aid in the timely diagnosis and management of anti-MDA-5 dermatomyositis.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 2","pages":"e01621"},"PeriodicalIF":0.6,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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