ACG Case Reports JournalPub Date : 2025-01-29eCollection Date: 2025-02-01DOI: 10.14309/crj.0000000000001593
Shivangini Duggal, Keith Garrison, Samantha Meza-Rodriguez, Ben Williams, Ioannis Konstantinidis, Marc J Zuckerman, Sherif E Elhanafi
{"title":"Association of Gastric Sarcina With Malignant Pyloric Stenosis.","authors":"Shivangini Duggal, Keith Garrison, Samantha Meza-Rodriguez, Ben Williams, Ioannis Konstantinidis, Marc J Zuckerman, Sherif E Elhanafi","doi":"10.14309/crj.0000000000001593","DOIUrl":"10.14309/crj.0000000000001593","url":null,"abstract":"<p><p><i>Sarcina ventriculi</i> (SV) is a Gram-positive cocci that thrives in the acidic stomach environment and may cause gastrointestinal symptoms. A 65-year-old woman with a history of <i>Helicobacter pylori</i> gastritis and diabetes presented with abdominal pain, vomiting, diarrhea, and weight loss. Initial esophagogastroduodenoscopy revealed pyloric stenosis with thickened prepyloric gastric folds, and endoscopic biopsy revealed SV without malignancy. Owing to persistent symptoms, endoscopic ultrasound was done with repeat biopsies and was nondiagnostic. Subsequently, a robotic gastrojejunostomy was done due to persistent gastric outlet obstruction symptoms. Surgical specimens revealed signet ring cell carcinoma. This case highlights the importance of suspecting underlying malignancy in patients with SV and the necessity of comprehensive diagnostic evaluation when endoscopic findings are inconclusive.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 2","pages":"e01593"},"PeriodicalIF":0.6,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11778090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-24eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001597
Albert Z Huang, Hyun Jae Kim, Billy Zhao, Daniel R Owen, Avni Jain, Daljeet Chahal, Eric M Yoshida
{"title":"Chimeric Antigen Receptor T-Cell-Associated Cholangiopathy: First Reported Case of a Complication of Chimeric Antigen Receptor T-Cell Therapy.","authors":"Albert Z Huang, Hyun Jae Kim, Billy Zhao, Daniel R Owen, Avni Jain, Daljeet Chahal, Eric M Yoshida","doi":"10.14309/crj.0000000000001597","DOIUrl":"10.14309/crj.0000000000001597","url":null,"abstract":"<p><p>Chimeric antigen receptor T-cell (CAR-T) therapy is a novel immunotherapy for the treatment of refractory malignancies. While various complications have been described previously, sclerosing cholangitis has not been reported. We report the first description of sclerosing cholangitis secondary to Tecartus CAR-T therapy in a 67-year-old man with refractory stage IV mantle cell lymphoma. As CAR-T therapy becomes increasingly used in clinical practice, it is critical to recognize potential hepatobiliary complications. Further research is needed to facilitate early diagnosis and to develop effective treatment strategies for managing these rare but severe complications.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01597"},"PeriodicalIF":0.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-21eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001587
Colin P Slaymaker, Bhargavram Channagiri Srinivas, Pranay Reddy, D Matthew Shoemaker, Andrea E Stand, Ryan K Rader
{"title":"Cytomegalovirus Colitis Masquerading as a Recurrent Colonic Polyp in a Patient With Neurofibromatosis Type 1.","authors":"Colin P Slaymaker, Bhargavram Channagiri Srinivas, Pranay Reddy, D Matthew Shoemaker, Andrea E Stand, Ryan K Rader","doi":"10.14309/crj.0000000000001587","DOIUrl":"10.14309/crj.0000000000001587","url":null,"abstract":"<p><p>Cytomegalovirus colitis most commonly affects immunocompromised patients, although it is a rare cause of gastrointestinal bleeding in immunocompetent patients. Older age, chronic disease, and critical illness are also important risk factors and may lead providers to consider the diagnosis in otherwise immunocompetent patients. Endoscopic presentation is variable and does not significantly influence outcomes. Although most immunocompetent, noncritically ill patients improve with or without antiviral treatment, mortality rates are as high as 71.4% in critically ill patients. Such mortality rates necessitate that intensive care providers remain wary of the diagnosis in any patient presenting with gastrointestinal bleeding. We present a rare case of cytomegalovirus colitis masquerading as a recurrent colonic mass in a patient with neurofibromatosis type 1.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01587"},"PeriodicalIF":0.6,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11749499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-17eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001582
Sarah Wehbe, Stephen A Firkins, Jacob R Sweeney, Halle C F Moore, Carol Rouphael
{"title":"Covert Breast Cancer Metastasis to the Gastrointestinal Tract: Is Extra Vigilance Needed?","authors":"Sarah Wehbe, Stephen A Firkins, Jacob R Sweeney, Halle C F Moore, Carol Rouphael","doi":"10.14309/crj.0000000000001582","DOIUrl":"https://doi.org/10.14309/crj.0000000000001582","url":null,"abstract":"<p><p>Breast cancer (BC) is a common cancer in females. Spread to the gastrointestinal tract is rare. This is a 61-year-old woman with history of T2N0M0 lobular BC treated 5 years earlier. She underwent endoscopic evaluation for new-onset anemia and was found to have multiple gastric ulcers, a normal-appearing duodenum, and subtle colonic nodules. Targeted and random biopsies of abnormal and normal findings, respectively, showed adenocarcinoma with diffuse immunohistochemical staining compatible with her BC history. This highlights the importance of maintaining a high suspicion index in patients with lobular BC and the utility of random biopsies in such cases.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01582"},"PeriodicalIF":0.6,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11741208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-17eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001598
Sangkyu Noh, Franklin Liu, Samuel H Cheong, Sasha Taleban
{"title":"Rare Finding of Rectal Squamous Metaplasia in Inflammatory Bowel Disease.","authors":"Sangkyu Noh, Franklin Liu, Samuel H Cheong, Sasha Taleban","doi":"10.14309/crj.0000000000001598","DOIUrl":"https://doi.org/10.14309/crj.0000000000001598","url":null,"abstract":"<p><p>Rectal squamous metaplasia in inflammatory bowel disease is rare. We present 2 cases of rectal squamous metaplasia, one in a patient with Crohn's disease and another with ulcerative colitis. Given the risk of malignant transformation, dysplasia surveillance is important particularly in areas of chronic inflammation. Furthermore, human papilloma virus (HPV) is involved in the pathogenesis of anal squamous cell carcinoma (SCC), but no guidelines exist in the United States for HPV prophylaxis against anal SCC in inflammatory bowel disease. HPV vaccination should be considered in high-risk patients younger than 45 years for prevention of anal SCC, including those with rectal squamous metaplasia.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01598"},"PeriodicalIF":0.6,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11741210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-10eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001588
Abigail Layton Ellington, Samuel Thierjung Tarry, Matthew Nigel Hugh Ellis, Steven B Clayton
{"title":"Situational Syncope Triggered by Swallowing.","authors":"Abigail Layton Ellington, Samuel Thierjung Tarry, Matthew Nigel Hugh Ellis, Steven B Clayton","doi":"10.14309/crj.0000000000001588","DOIUrl":"10.14309/crj.0000000000001588","url":null,"abstract":"<p><p>Syncope is characterized by a transient loss of consciousness. Swallow syncope, a rare cause of syncope, is caused by vagus nerve activation resulting in vasodilation and bradycardia, thus causing transient hypotension and cerebral hypoperfusion. It is diagnosed through clinical history, cardiac, and esophageal evaluation. We present a case of swallow syncope in a patient with significant cardiac history. Initial cardiac and esophageal testing was normal. Long-term telemetry revealed bradycardia with swallowing, and the patient underwent pacemaker placement. Swallow syncope is associated with a variety of esophageal and cardiac conditions. Management involves addressing the underlying cause; pacemaker placement is sometimes necessary. KEYWORDS: syncope; swallow syncope; reflex syncope; pacemaker.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01588"},"PeriodicalIF":0.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11723683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-09eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001590
Mark C Wang, Aileen Bui, Supisara Tintara, Kambiz Etesami, Brian Kim
{"title":"Recurrent Bacteremia and Cholangitis From Eroded Hepatic Artery Pseudoaneurysm Coil Into the Common Hepatic Duct: A Rare Indication for Liver Transplantation.","authors":"Mark C Wang, Aileen Bui, Supisara Tintara, Kambiz Etesami, Brian Kim","doi":"10.14309/crj.0000000000001590","DOIUrl":"10.14309/crj.0000000000001590","url":null,"abstract":"<p><p>Liver transplant may be necessary to manage infectious complications from severe structural biliary disease. In this report, we describe a 71-year-old woman with history of coil-embolized hepatic artery pseudoaneurysm who subsequently developed biliary obstruction resulting from coil erosion into the common hepatic duct. Resultant complications included recurrent cholangitis, bacteremia, and numerous hepatic abscesses. Because of lack of improvement with medical management, the patient underwent liver transplantation and coil removal as the definitive treatment modality. Altogether, this report explores a unique case of liver transplantation as source control for a patient with an active disseminated infection.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01590"},"PeriodicalIF":0.6,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11717500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-09eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001580
Getanshu Malik, Eric Herget, Henry H Nguyen, Mark G Swain
{"title":"Prominent Eustachian Valve Mimicking a Transjugular Intrahepatic Portosystemic Shunt-Associated Thrombosis.","authors":"Getanshu Malik, Eric Herget, Henry H Nguyen, Mark G Swain","doi":"10.14309/crj.0000000000001580","DOIUrl":"10.14309/crj.0000000000001580","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01580"},"PeriodicalIF":0.6,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11717499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACG Case Reports JournalPub Date : 2025-01-08eCollection Date: 2025-01-01DOI: 10.14309/crj.0000000000001591
Alexandra Kimchy, Fatima Khambaty, Gustavo Marino
{"title":"Ischemic Jejunitis as a Late Complication of Roux-en-Y Gastric Bypass.","authors":"Alexandra Kimchy, Fatima Khambaty, Gustavo Marino","doi":"10.14309/crj.0000000000001591","DOIUrl":"https://doi.org/10.14309/crj.0000000000001591","url":null,"abstract":"<p><p>The rising prevalence of obesity has led to a substantial investment in the advancement of treatment options for the disease and its comorbid conditions including lifestyle, pharmacologic, and procedural interventions. In this study, we describe a patient with a history of Roux-en-Y gastric bypass who was diagnosed with ischemic jejunitis on upper endoscopy because of the development of an internal hernia, a known late complication of bariatric surgery. This case highlights the diagnostic utility of endoscopy in postgastric bypass complications and the need for safer alternatives to surgery that have the potential to achieve significant weight loss such as bariatric endoscopic therapies.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 1","pages":"e01591"},"PeriodicalIF":0.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11709216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}