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A Therapeutic Tightrope: Managing Coexisting Crohn Disease and Systemic Lupus Erythematosus With Risankizumab. 治疗钢丝：用利尚单抗治疗克罗恩病和系统性红斑狼疮
IF 0.5
ACG Case Reports Journal Pub Date : 2025-09-08 eCollection Date: 2025-09-01 DOI: 10.14309/crj.0000000000001830
Hamdan AlAwadhi, Muna Almutawa, Sara El Ouali, Zaher Koutoubi, Esat Memisoglu, Ahmad AlDuaij, Rajaie Namas
{"title":"A Therapeutic Tightrope: Managing Coexisting Crohn Disease and Systemic Lupus Erythematosus With Risankizumab.","authors":"Hamdan AlAwadhi, Muna Almutawa, Sara El Ouali, Zaher Koutoubi, Esat Memisoglu, Ahmad AlDuaij, Rajaie Namas","doi":"10.14309/crj.0000000000001830","DOIUrl":"10.14309/crj.0000000000001830","url":null,"abstract":"<p><p>The coexistence of systemic lupus erythematosus (SLE) and Crohn disease (CD) is rare and presents significant diagnostic and therapeutic challenges due to overlapping clinical, radiologic, and histologic features. We present a 24-year-old woman with SLE, chronic immune thrombocytopenic purpura, and newly diagnosed CD treated with risankizumab, an interleukin-23 inhibitor approved for CD. She achieved complete clinical and radiologic remission of CD without SLE flares over 12 months. To the best of our knowledge, this represents the first documented case of risankizumab successfully used in a patient with SLE and CD. Further research is needed to assess the long-term safety and wider applicability of interleukin-23 inhibitors for this underserved patient population.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 9","pages":"e01830"},"PeriodicalIF":0.5,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Index Hepatic Decompensation: Hepatic Hydrothorax Without Signs of Clinically Significant Portal Hypertension Diagnosed With Radioisotope Scintigraphy. 肝代偿失代偿：肝性胸水，无明显门静脉高压症，放射性同位素显像诊断。
IF 0.5
ACG Case Reports Journal Pub Date : 2025-09-04 eCollection Date: 2025-09-01 DOI: 10.14309/crj.0000000000001819
Alisia C Gunderson, Brendan Andres, Joseph R Gunderson, Carl Sabottke, Bital Savir-Baruch, Bujji Ainapurapu
{"title":"Index Hepatic Decompensation: Hepatic Hydrothorax Without Signs of Clinically Significant Portal Hypertension Diagnosed With Radioisotope Scintigraphy.","authors":"Alisia C Gunderson, Brendan Andres, Joseph R Gunderson, Carl Sabottke, Bital Savir-Baruch, Bujji Ainapurapu","doi":"10.14309/crj.0000000000001819","DOIUrl":"10.14309/crj.0000000000001819","url":null,"abstract":"<p><p>Hepatic hydrothorax (HH) occurs in 4%-12% of patients with cirrhosis and rarely presents without accompanying evidence of clinically significant portal hypertension (CSPH). We report the case of a 65-year-old man with cirrhosis without prior decompensation, congestive heart failure, and recurrent right-sided pleural effusion. CSPH was not otherwise observed despite thorough laboratory, radiologic, and endoscopic evaluation. However, pleural fluid analysis revealed a serum effusion albumin gradient of 1.6, raising suspicion for a hepatic etiology. Suspected HH was diagnosed by technetium-99m sulfur colloid peritoneal cavity scintigraphy. As the index decompensating event, the patient's HH initiated a liver transplant evaluation in the absence of other evidence of CSPH.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 9","pages":"e01819"},"PeriodicalIF":0.5,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Double Endoscopic Bypass: A Durable Solution to Pair With Improving Systemic Therapy for Metastatic Cancer. 双重内窥镜旁路：与改善转移性癌症的全身治疗相结合的持久解决方案。
IF 0.5
ACG Case Reports Journal Pub Date : 2025-09-02 eCollection Date: 2025-09-01 DOI: 10.14309/crj.0000000000001821
Nikita Parkash, Owen McKay, Andrew Strickland, Daniel Croagh
{"title":"Double Endoscopic Bypass: A Durable Solution to Pair With Improving Systemic Therapy for Metastatic Cancer.","authors":"Nikita Parkash, Owen McKay, Andrew Strickland, Daniel Croagh","doi":"10.14309/crj.0000000000001821","DOIUrl":"10.14309/crj.0000000000001821","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 9","pages":"e01821"},"PeriodicalIF":0.5,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12404703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Example of Cascade Stomach. 瀑布胃的一个例子。
IF 0.5
ACG Case Reports Journal Pub Date : 2025-09-02 eCollection Date: 2025-09-01 DOI: 10.14309/crj.0000000000001825
Jesse Fletcher, Justin Howard
{"title":"An Example of Cascade Stomach.","authors":"Jesse Fletcher, Justin Howard","doi":"10.14309/crj.0000000000001825","DOIUrl":"10.14309/crj.0000000000001825","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 9","pages":"e01825"},"PeriodicalIF":0.5,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12404702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Jejunal Angiosarcoma. 原发性空肠血管肉瘤。
IF 0.5
ACG Case Reports Journal Pub Date : 2025-08-27 eCollection Date: 2025-08-01 DOI: 10.14309/crj.0000000000001818
Michelle Mai, Sapana Gupta, Kanhai Farrakhan, Shaolei Lu, Paul Akerman, May Min
{"title":"Primary Jejunal Angiosarcoma.","authors":"Michelle Mai, Sapana Gupta, Kanhai Farrakhan, Shaolei Lu, Paul Akerman, May Min","doi":"10.14309/crj.0000000000001818","DOIUrl":"10.14309/crj.0000000000001818","url":null,"abstract":"<p><p>Primary jejunal angiosarcoma is an aggressive and rare soft-tissue neoplasm with a poor prognosis. Multiple modalities such as endoscopic intervention, radiographic imaging, and immunohistochemistry are often used to confirm the diagnosis. Only 62 cases have been reported in the literature of primary jejunal angiosarcoma, and the majority of these patients had distant metastases at initial staging. This is a case of a 51-year-old man who presented with melena found to have a jejunal mass and diagnosed with angiosarcoma with no metastases detected on initial staging. The diagnosis of angiosarcoma was confirmed with histomorphology and immunohistochemistry. Despite early tumor staging and successful small bowel resection, 6 months postsurgical resection patient later presented with metastatic. This case report highlights the importance of a comprehensive diagnostic strategy and raises consideration for earlier systemic therapy in localized neoadjuvant therapy in early-stage small bowel angiosarcoma.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 8","pages":"e01818"},"PeriodicalIF":0.5,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12384992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic Treatment of a Colovesical Fistula Using a Through-The-Scope Clip Designed for Large Defect Closure. 内窥镜下膀胱瘘的治疗：使用专为大缺陷闭合而设计的穿过镜夹。
IF 0.5
ACG Case Reports Journal Pub Date : 2025-08-27 eCollection Date: 2025-08-01 DOI: 10.14309/crj.0000000000001813
Samuel Jun Ming Lim, Clarence Kah Wai Kwan
{"title":"Endoscopic Treatment of a Colovesical Fistula Using a Through-The-Scope Clip Designed for Large Defect Closure.","authors":"Samuel Jun Ming Lim, Clarence Kah Wai Kwan","doi":"10.14309/crj.0000000000001813","DOIUrl":"10.14309/crj.0000000000001813","url":null,"abstract":"<p><p>We present a patient who underwent endoscopic treatment of a colovesical fistula (CVF) using a through-the-scope clip (TTSC) designed for large defect closure. She was admitted for recurrent urosepsis. She declined surgery but agreed for endoscopic therapy. An over-the-scope clip was not used as the CVF was in close proximity to the right vesicoureteric junction. Conventional TTSCs failed to close the CVF due to fibrotic tissue at the CVF opening. A TTSC designed for large defect closure (MANTIS Clip, Boston Scientific, Marlborough, MA) successfully closed the CVF. The patient was last reviewed 9 months after endoscopic closure, with no further episodes of urosepsis.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 8","pages":"e01813"},"PeriodicalIF":0.5,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12384882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adult-Onset Pancreatoblastoma. 成人Pancreatoblastoma。
IF 0.5
ACG Case Reports Journal Pub Date : 2025-08-25 eCollection Date: 2025-08-01 DOI: 10.14309/crj.0000000000001814
Thomas Gonzales, Sultan Mahmood, Saifur R Khan, Aatur Singhi
{"title":"Adult-Onset Pancreatoblastoma.","authors":"Thomas Gonzales, Sultan Mahmood, Saifur R Khan, Aatur Singhi","doi":"10.14309/crj.0000000000001814","DOIUrl":"10.14309/crj.0000000000001814","url":null,"abstract":"<p><p>Pancreatoblastoma (PB), an extremely rare malignancy of the pancreatic tissue, comprises less than 1% of all pancreatic tumors. Owing to the rarity of the malignancy and the potential for multiple differential diagnoses, adult-onset PB can be challenging to diagnose. The hallmark characteristic in diagnosing adult PB is found histologically. In approximately 90% of cases, squamous corpuscles are observed. We present the case of a patient diagnosed with adult-onset PB, who presented with key clinical and pathological features, as well as rarer characteristics, associated with the malignancy.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 8","pages":"e01814"},"PeriodicalIF":0.5,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12377294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expanding Horizons of Vascular Interventions: Endoscopic Ultrasound-Guided Angioembolization for a Refractory Upper Gastrointestinal Bleed From a Gastric Dieulafoy Lesion. 扩大血管介入的视野：内镜下超声引导血管栓塞治疗胃十二指肠病变难治性上消化道出血。
IF 0.5
ACG Case Reports Journal Pub Date : 2025-08-22 eCollection Date: 2025-08-01 DOI: 10.14309/crj.0000000000001816
Jahnvi Dhar, Ujjwal Gorsi, Saroj Kant Sinha, Jayanta Samanta
{"title":"Expanding Horizons of Vascular Interventions: Endoscopic Ultrasound-Guided Angioembolization for a Refractory Upper Gastrointestinal Bleed From a Gastric Dieulafoy Lesion.","authors":"Jahnvi Dhar, Ujjwal Gorsi, Saroj Kant Sinha, Jayanta Samanta","doi":"10.14309/crj.0000000000001816","DOIUrl":"10.14309/crj.0000000000001816","url":null,"abstract":"","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 8","pages":"e01816"},"PeriodicalIF":0.5,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12373075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pseudo-Pseudo Polyp: Spindle Cell Sarcoma at an Ileocolonic Anastomosis. 假性息肉：回肠结肠吻合处的梭形细胞肉瘤。
IF 0.5
ACG Case Reports Journal Pub Date : 2025-08-22 eCollection Date: 2025-08-01 DOI: 10.14309/crj.0000000000001817
Ines Varela Knorr, James Marion, Jennifer Claytor
{"title":"Pseudo-Pseudo Polyp: Spindle Cell Sarcoma at an Ileocolonic Anastomosis.","authors":"Ines Varela Knorr, James Marion, Jennifer Claytor","doi":"10.14309/crj.0000000000001817","DOIUrl":"10.14309/crj.0000000000001817","url":null,"abstract":"<p><p>Anastomotic inflammatory polyps are a known source of gastrointestinal bleeding in patients who have undergone bowel resection, but an anastomotic spindle cell sarcoma with myogenic differentiation has never been reported. We present the case of a patient with occult gastrointestinal bleeding 6 years after an ileocolic resection for an incarcerated hernia and discuss surveillance in patients with these rare polyps.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 8","pages":"e01817"},"PeriodicalIF":0.5,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12373086/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of a Pseudoaneurysm After Carotid-Esophageal Fistula Repair Secondary to Button Battery Ingestion in an Infant. 婴儿误食纽扣电池后颈-食管瘘修复后假性动脉瘤的处理。
IF 0.5
ACG Case Reports Journal Pub Date : 2025-08-22 eCollection Date: 2025-08-01 DOI: 10.14309/crj.0000000000001811
Michal T Ruprecht, Vanesa Carlota Andreu Arasa, Luisa Fernanda Atunes Ortega, Alcy R Torres
{"title":"Management of a Pseudoaneurysm After Carotid-Esophageal Fistula Repair Secondary to Button Battery Ingestion in an Infant.","authors":"Michal T Ruprecht, Vanesa Carlota Andreu Arasa, Luisa Fernanda Atunes Ortega, Alcy R Torres","doi":"10.14309/crj.0000000000001811","DOIUrl":"10.14309/crj.0000000000001811","url":null,"abstract":"<p><p>Button battery ingestion is a significant cause of pediatric foreign body emergencies, often leading to severe complications. We present the case of an infant who developed a left common carotid-esophageal fistula after button battery ingestion, which was further complicated by the formation of a pseudoaneurysm. The diagnosis was confirmed through follow-up imaging, and the pseudoaneurysm was successfully treated using a flow diversion stent. The patient remained clinically stable without neurological deficits. This case underscores the critical importance of early diagnosis and intervention to prevent life-threatening complications such as hemorrhage and stroke. In addition, it highlights the necessity of follow-up imaging studies, even in asymptomatic patients, to monitor for delayed complications and inform ongoing management.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 8","pages":"e01811"},"PeriodicalIF":0.5,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12373100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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