Acta radiologica open最新文献

{"title":"Pericoronary fat attenuation in stenotic and vulnerable coronary artery plaques: Implications for coronary artery disease and associated conditions.","authors":"Burak Günay, Muzaffer Savaş Tepe, Halis Harun Öztürk, Atakan Küskün, Murat Gençbay","doi":"10.1177/20584601251342312","DOIUrl":"10.1177/20584601251342312","url":null,"abstract":"<p><strong>Background: </strong>Pericoronary adipose tissue density (PCAT) is a parameter that quantifies inflammation and atherosclerosis around the coronary arteries.</p><p><strong>Purpose: </strong>To investigate the correlation between PCAT and plaque features, stenosis degrees in coronary arteries (LAD, RCA, Cx) with stenotic vulnerable plaques.</p><p><strong>Material and methods: </strong>A Retrospective study including 103 patients (64M, 39F) who underwent coronary computed tomography was retrospectively examined at a single center. PCAT and high-risk plaques were measured independently and compared to stenosis and coronary artery type. Adipose tissue attenuation, ranging from -180 to -25 HU, was measured along the plaque's length and in a 0.5-1 mm region around the perilesional coronary arteries.</p><p><strong>Results: </strong>The PCAT values increases with the degree of stenosis in the LAD, Cx, and RCA (r = 0.9161, <i>p</i> < .001; r = 0.9717, <i>p</i> < .001; r = 0.9315, <i>p</i> < .001, respectively). PCAT values demonstrate a positive pattern when plaque length increases in all coronary arteries (r = -0.6316, <i>p</i> < .001; r = -0.8825, <i>p</i> < .001; r = -0.7529, <i>p</i> < .001; LAD, Cx, RCA). PCAT values differed significantly based on plaque type in all coronary arteries. Calcified plaques showed statistically significant differences compared to both soft and mixed plaques (<i>p</i> < .05). Patients with positive remodeling had PCAT values of -69.43 (±8.76) HU, while cases without positive remodeling had PCAT values of -84.54 (±7.65) HU, indicating a significant difference (<i>p</i> < .05).</p><p><strong>Conclusion: </strong>The combined evaluation of plaque features, stenosis degree, and PCAT provides a more accurate prediction of possible acute coronary syndrome cases than analyzing stenosis degree alone.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 5","pages":"20584601251342312"},"PeriodicalIF":0.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12099116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular-variant cardiac amyloid: Cardiac MRI and histopathological appearances.","authors":"Sebastian Flynn, Kamal Fadalla, Aurelie Fabre, Jonathan D Dodd","doi":"10.1177/20584601251343824","DOIUrl":"10.1177/20584601251343824","url":null,"abstract":"<p><p><i>Cardiac amyloidosis</i> is an infiltrative cardiomyopathy caused by the deposition of abnormally folded proteins within the myocardium. Several amyloid subtypes have been documented, with diagnosis supported by abnormal serum plasma electrophoresis, multimodality imaging, and endomyocardial biopsy. Herein, we describe the atypical MRI findings of vascular-variant cardiac amyloid supported by histopathological diagnosis. Knowledge of the vascular-variant cardiac amyloid, in which amyloid deposits in the myocardial vasculature rather than the interstitium, will enable clinicians to proceed down appropriate diagnostic and treatment pathways.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 5","pages":"20584601251343824"},"PeriodicalIF":0.9,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A multi-institutional CT practices survey of pediatric head, chest, and abdomen-pelvis examinations.","authors":"Elena Tonkopi, Megan Iwaskow, Cecilie Karlstad Lønningen, Alex Myrvold Johansen, Sivethan Suganthan, Yulia Kotlyarova, Mohamed Badawy, Catherine Gunn, Jessica Kimber, Dana Jackson, Mercy Afadzi Tetteh, Tanja Oestgaard Holter, Safora Johansen","doi":"10.1177/20584601251340974","DOIUrl":"https://doi.org/10.1177/20584601251340974","url":null,"abstract":"<p><p><b>Background:</b> Pediatric patients are particularly vulnerable to the stochastic effects of ionizing radiation. Despite these risks, CT remains diagnostically essential in pediatric care. Diagnostic reference levels (DRLs) have been recommended as a radiation dose optimization tool to address these concerns. <b>Purpose:</b> This study aims to survey pediatric CT practices at different facilities in Australia, Canada, and Norway and to suggest local DRLs (LDRLs) at each facility as a baseline for future surveys. <b>Materials and methods:</b> Radiation dose indices, imaging, and demographic data were collected retrospectively at each facility using PACS for unenhanced CT head, contrast-enhanced chest, and contrast-enhanced abdomen-pelvis examinations in patients from 0 to 15 years of age. The LDRL values were determined for CT dose indices and size-specific dose estimate (SSDE) values. The Kruskal-Wallis test assessed the equality of populations across countries for all dosimetric quantities. Ordinary least squares regression was employed to express SSDE as a linear function of patient weight. <b>Results:</b> The LDRLs for Australian, Canadian, and Norwegian facilities were determined and examined for each age group. Canadian and Norwegian LDRL data were most similar, with Australian values being comparatively lower for all categories except for 11-15-year-old abdomen-pelvis examinations. The SSDE and patient weight were significantly positively correlated for each examination/country combination. <b>Conclusion:</b> The proposed local reference levels can provide local baselines for dose optimization and continuous dose assessment.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 5","pages":"20584601251340974"},"PeriodicalIF":0.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12075985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparisons of turbo spin-echo and echo-planar diffusion-weighted imaging of the female pelvic region on 1.5T and 3.0T magnetic resonance systems.","authors":"Hisatoshi Araki, Takeshi Yoshizako, Rika Yoshida, Hiroya Asou, Yasushi Kaji","doi":"10.1177/20584601251339018","DOIUrl":"https://doi.org/10.1177/20584601251339018","url":null,"abstract":"<p><strong>Background: </strong>There have been no previous studies comparing the effectiveness of echo-planar imaging (EPI)-diffusion-weighted imaging (DWI) and turbo spin echo (TSE)-DWI for female pelvic imaging on 1.5T and 3.0T magnetic resonance imaging (MRI) systems.</p><p><strong>Purpose: </strong>This retrospective study compared EPI-DWI and TSE-DWI of the female pelvis at 1.5T and 3.0T MRI to evaluate image quality, geometric distortion, and apparent diffusion coefficient (ADC) values for optimal clinical diagnosis.</p><p><strong>Materials and methods: </strong>Thirty-nine patients at 1.5T and 71 patients at 3.0T underwent both TSE- and EPI-DWI with b-values of 0 and 1000 s/mm². Spatial resolution was matched between systems and sequences. Geometric distortion, contrast ((uterine myometrium signal intensity (SI) - gluteal muscle SI)/(uterine myometrium SI + gluteal muscles SI)), and ADC values of the uterine myometrium and lesions were compared. Qualitative assessment included ghosting artifacts, image contrast, and overall image quality.</p><p><strong>Results: </strong>There was no significant difference in patient demographics between 1.5T and 3.0T groups. TSE-DWI demonstrated significantly less distortion than EPI-DWI at both field strengths (<i>p</i> < .05). Contrast was higher with TSE-DWI than EPI-DWI at 3.0T (<i>p</i> < .05) and was greater at 3.0T than 1.5T. ADC values of malignancies differed significantly from the uterus and benign lesions across all sequences and field strengths (<i>p</i> < .05). TSE-DWI showed higher ghosting artifact scores than EPI-DWI at 3.0T (<i>p</i> = .019), but no other significant differences in qualitative evaluation were noted.</p><p><strong>Conclusion: </strong>TSE-DWI provided superior contrast with reduced distortion compared to EPI-DWI in the female pelvis at both field strengths, with TSE-DWI demonstrating greater effectiveness at 3.0T.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 5","pages":"20584601251339018"},"PeriodicalIF":0.9,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Massive lower gastrointestinal hemorrhage due to primary internal iliac arterial-sigmoid colon fistula.","authors":"Qi Li, Haoyi Wang, Zhang Chen, Zhen Ni","doi":"10.1177/20584601251339008","DOIUrl":"https://doi.org/10.1177/20584601251339008","url":null,"abstract":"<p><p>Primary aortoenteric fistula is a rare entity with high mortality. Depending on the location of the fistula, primary aortoenteric fistulas may lead to upper or lower gastrointestinal hemorrhages. The majority of primary aortoenteric fistulas are associated with atherosclerosis or aneurysms of the aorta, without any previous aortic procedure. Local inflammation, compression, or erosion may lead to rupture of the aneurysm. Owing to difficulties in immediate and correct diagnosis, effective treatment of primary aortoenteric fistulas is often delayed, leading to almost 100% mortality in untreated patients. Here, we report a case of a repetitive mass of lower gastrointestinal hemorrhage due to a primary internal iliac arterial-sigmoid colon fistula. Finally, the patient was managed successfully through endovascular coil embolization.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 5","pages":"20584601251339008"},"PeriodicalIF":0.9,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12041694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MMP-9 metalloproteinase and its regulator are not associated with mid-term CT residual abnormalities in patients with COVID-19 pneumonia.","authors":"Monica Mattone, Giorgio Maria Masci, Nicholas Landini, Maria Antonella Zingaropoli, Carlo Catalano, Maria Rosa Ciardi, Valeria Panebianco","doi":"10.1177/20584601251330563","DOIUrl":"https://doi.org/10.1177/20584601251330563","url":null,"abstract":"<p><strong>Background: </strong>COVID-19 patients may have residual pulmonary alterations after the acute disease, with fibrotic-like alterations. Since metalloproteinases (MMP) and their regulators may be involved in inflammation and abnormal repair processing, we aimed to investigate the correlations between MMP-9, a tissue inhibitor of metalloproteinases (TIMP-1) and chest CT abnormalities in acute phase and mid-term follow-up.</p><p><strong>Methods: </strong>COVID-19 patients with plasma analyses and CT scans performed at acute onset and 3 months after discharge (T post) were evaluated. MMP-9, TIMP-1, and MMP-9/TIMP-1 ratio were analyzed. CT extents of COVID-19 pneumonia and fibrotic-like alterations were visually scored (score range 0-25). Spearman rank correlation analysis (<i>p</i>-value <.05) was computed between acute and mid-term plasma analyses and CT scores.</p><p><strong>Results: </strong>39 patients were enrolled. At hospital admission, MMP-9, TIMP-1, and MMP-9/TIMP-1 had a median of 240.5 ng/mL, 258.8 ng/mL, and 0.9. The median CT global and fibrotic-like scores were 9 and 6. At T post, MMP-9 and TIMP-1 were not statistically different (<i>p</i>-value <.05). There was a reduction of CT global score (<i>p</i>-value = .00007). A significant correlation was found between MMP-9 and CT global score at hospital admission (ρ = 0.456, <i>p</i>-value = .003) and between MMP-9/TIMP-1 ratio and CT global score at hospital admission (ρ = 0.406, <i>p</i>-value = .009). No other significant correlations were found between plasma enzymes and CT alterations, both in acute and mid-term follow-up.</p><p><strong>Conclusion: </strong>MMP-9 plasma levels and MMP-9/TIMP-1 ratio correlate with lung involvement during the acute phase. None of the levels of MMP-9, TIMP-1, and MMP-9/TIMP-1 ratio may be adopted as predictors of residual pulmonary alterations in mid-term follow-up.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 4","pages":"20584601251330563"},"PeriodicalIF":0.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A deep learning algorithm for radiographic measurements of the hip versus human CT measurements: An intermodality agreement study.","authors":"Christian Greve Jensen, Benjamin Schnack Rasmussen, Søren Overgaard, Claus Varnum, Martin Haagen Haubro, Janni Jensen","doi":"10.1177/20584601251330554","DOIUrl":"10.1177/20584601251330554","url":null,"abstract":"<p><strong>Background: </strong>Hip dysplasia (HD) is a prevalent cause of non-traumatic hip pain, which may result in osteoarthritis. Radiological measurements of HD exhibit variability based on reader and imaging modality, why it is important to know the agreement between different measurement methods.</p><p><strong>Purpose: </strong>To estimate agreement between measurements of lateral center edge angle (LCEA) and acetabular inclination angle (AIA) made, respectively, on Computed Tomography (CT) scans by humans and radiographs analyzed by an algorithm. To estimate impact of pelvic rotation on agreement between CT and radiographic measurements.</p><p><strong>Material and methods: </strong>CT measurements were retrospectively extracted from 172 radiology reports. Radiographs were analyzed using an algorithm. Bland-Altman analysis assessed agreement between CT and radiographic measurements. Regression analyses estimated impact of pelvic rotation on inter-modality agreement.</p><p><strong>Results: </strong>Mean measured bias (95% confidence interval [CI]) between CT and radiographs for LCEA of right/left hip was 5.53° (95% CI: 4.81 to 6.24) and 5.13 (95% CI: 4.43 to 5.83), respectively. Corresponding values for right/left AIA were 1.08 (95% CI: 0.49 to 1.67) and -0.03 (95% CI: -0.60 to 0.05). Pelvic rotation affected right LCEA and AIA measurements, with a change in obturator foramen index of, respectively, 0.35 and 0.6 resulting in approximately 2° change in values.</p><p><strong>Conclusion: </strong>There was a significant difference in agreement of 5° between CT and radiographs for the LCEA bilaterally. The difference for the AIA was between 0 and 1°, probably of little clinical significance. Pelvic rotation slightly affected bias of the right LCEA, suggesting minimal clinical impact of a slightly rotated pelvis.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 4","pages":"20584601251330554"},"PeriodicalIF":0.9,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left bundle branch block-induced pseudo-infarction: Cardiac MRI pitfall.","authors":"Sebastian Flynn, Desmond Killick, Ken McDonald, Jonathan Dodd","doi":"10.1177/20584601251322487","DOIUrl":"10.1177/20584601251322487","url":null,"abstract":"<p><p>Cardiac MRI serves as an indispensable tool for diagnosing and characterizing myocardial pathology. Late gadolinium enhancement (LGE) imaging enables assessing myocardial scar formation and regional fibrosis. Here, we present a case involving a young woman with congenital dilated cardiomyopathy, showcasing LGE along the interventricular septum. This LGE distribution likely arises from altered ventricular hemodynamics secondary to bundle branch block rather than ischemia. This insight has significant implications for guiding clinical management and avoiding unnecessary interventions.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 3","pages":"20584601251322487"},"PeriodicalIF":0.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic yield and complications of CT-guided biopsy of lung lesions as a radiological outpatient clinic procedure.","authors":"Katrine Bitsch Johansen, John Valtersson, Christian B Laursen, Bo Mussmann, Benjamin Rasmussen, Ole Graumann, Pia Iben Pietersen","doi":"10.1177/20584601251326485","DOIUrl":"10.1177/20584601251326485","url":null,"abstract":"<p><strong>Background: </strong>Computerized tomography-guided transthoracic needle biopsy (CT-TTNB) plays an important role in the diagnostic work-up of lung lesions. The literature reports varying results on complication rates, severity of complications, and diagnostic yield.</p><p><strong>Purpose: </strong>To evaluate CT-TTNB as a radiological outpatient clinic procedure and explore diagnostic yield and complication rates.</p><p><strong>Material and methods: </strong>Between January 2017 and October 2019, a total of 559 patients underwent CT-TTNB. Patient records and CT scans were retrospectively reviewed and patient characteristics, lesion characteristics, biopsy procedure, and per- and post-procedural complications, as well as pathological diagnosis, were registered.</p><p><strong>Results: </strong>Of 559 patients included, 511 had biopsies performed. Thereby, 48 biopsies (8.6%) were discontinued because of patient compliance issues and/or the occurrence of pneumothorax before the biopsy was performed. The overall pneumothorax rate was 49.2% (<i>n</i> = 275 of 559 patients). Insertion of a drainage catheter was needed in 85 of the 275 patients with pneumothorax. Parenchymal bleeding was seen in 26.5% of the patients and haemoptysis in 5.5%. No cases of bleeding or haemoptysis required intervention or admission. Small mean lesion size and increased distance from pleura to the lesion were associated with a higher occurrence of complications. A conclusive pathological diagnosis was obtained in 278 of 511 (54.4%) biopsies. No patients were re-admitted after the two-hour observational period in the radiological department.</p><p><strong>Conclusion: </strong>CT-TTNB as an outpatient clinic procedure is feasible but has a moderate diagnostic yield and relatively high complication rates for minor complications.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 3","pages":"20584601251326485"},"PeriodicalIF":0.9,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperintensity of the left piriform cortex and amygdala on T2-weighted FLAIR images in patients with probable Alzheimer's disease correlates with cerebral cortical atrophy.","authors":"Hiroshi Ishizaka, Akiko Sekine, Minoru Naka, Saeki Nakano, Hiroyuki Nagase, Yoshito Tsushima","doi":"10.1177/20584601251317629","DOIUrl":"10.1177/20584601251317629","url":null,"abstract":"<p><strong>Background: </strong>The left piriform cortex and amygdala (PC&A) tend to be slightly hyperintense relative to the right PC&A on T2-weighted fluid-attenuated inversion recovery (T2W-FLAIR) images in patients with probable Alzheimer's disease (pAD). This likely represents the antecedent and thus advanced degeneration of the left PC&A.</p><p><strong>Purpose: </strong>To investigate the relationship between left PC&A hyperintensities and cerebral cortical atrophy on magnetic resonance (MR) voxel-based morphometry in patients with pAD and discuss how this finding could relate to AD progression.</p><p><strong>Material and methods: </strong>Patients with pAD (<i>n</i> = 47; age range = 68-93 years, mean = 80.8 ± 6.7 years; 14 men and 33 women) who underwent T2W-FLAIR imaging and MR morphometric study using a voxel-based specific regional analysis system for AD (VSRAD) were retrospectively examined. To measure signal intensity ratios of the left to right PC&A (L-PC&A/R-PC&A), regions of interest (ROIs) were set on the transaxial images in which both PC&As were most broadly depicted; the ROIs were defined as large as possible. Correlations between the L-PC&A/R-PC&A and medial temporal lobe cortical atrophy (MTLCA) as well as whole cerebral cortical atrophy (WCCA) on VSRAD were determined. Correlation between the L-PC&A/R-PC&A and age was also determined.</p><p><strong>Results: </strong>The L-PC&A/R-PC&A correlated with both MTLCA (r = 0.375, <i>p</i> = .010, 95% confidence interval [CI] = 0.095-0.600) and WCCA (r = 0.576, <i>p</i> < .001, 95% CI = 0.343-0.742). The L-PC&A/R-PC&A did not correlate with age (r = 0.013, <i>p</i> = .932, 95% CI = -0.282-0.305).</p><p><strong>Conclusion: </strong>Left-sided dominance of PC&A degeneration appeared to accelerate with the progression of AD stages.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 2","pages":"20584601251317629"},"PeriodicalIF":0.9,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}