Acta radiologica openPub Date : 2025-09-25eCollection Date: 2025-09-01DOI: 10.1177/20584601251379482
Niko Murto, Teija Lund, Hannu Kautiainen, Katariina Luoma, Liisa Kerttula
{"title":"Progression of lumbar disc degeneration: A 14-year follow-up study examining Pfirrmann grading and its individual disc components.","authors":"Niko Murto, Teija Lund, Hannu Kautiainen, Katariina Luoma, Liisa Kerttula","doi":"10.1177/20584601251379482","DOIUrl":"10.1177/20584601251379482","url":null,"abstract":"<p><strong>Background: </strong>Lumbar disc degeneration (LDD) is frequently evaluated using the Pfirrmann classification. While this composite grading system provides an overview of degeneration severity, it may oversimplify LDD by overlooking variability in individual disc components, reducing its effectiveness in longitudinal studies and constraining its applicability in artificial intelligence-based image analysis.</p><p><strong>Purpose: </strong>To examine the 14-year progression of LDD using the Pfirrmann classification and its individual components, and to evaluate the potential of component-based analysis.</p><p><strong>Material and methods: </strong>LDD was assessed using MRI in 19 males (95 discs) at ages 37 and 51 by two radiologists. Evaluations included Pfirrmann grading, quantitative nucleus pulposus (NP) signal intensity, and visual grading of NP inhomogeneity, annulus fibrosus (AF) border distinction, and disc height (DH). Analyses included longitudinal changes in LDD variables and correlations between Pfirrmann grading and disc components. To assess overall LDD, a summary score was calculated by summing individual disc grades.</p><p><strong>Results: </strong>Pfirrmann grading correlated strongly with AF border distinction, moderately with NP signal intensity, and weakly with NP inhomogeneity and DH. Pfirrmann summary score (range 5-25) increased by 3 points over time. Variability was observed in the progression of individual disc component degeneration. While mean NP signal intensity significantly decreased, some discs exhibited increase.</p><p><strong>Conclusion: </strong>This longitudinal study highlights complexity of LDD and variability in disc component changes. While Pfirrmann classification captures overall degeneration, its limitations in detecting subtle variations in disc components suggest a need for more detailed assessments to enhance diagnostic precision and support the development of automated analysis tools.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 9","pages":"20584601251379482"},"PeriodicalIF":1.0,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12475308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cervical spine MRI findings leading to diagnosis of hypothyroid myopathy in dropped head syndrome: A case report.","authors":"Chiaki Sato, Asako Yamamoto, Megumi Katsumata, Minami Hirasawa, Yuki Hatanaka, Hiroshi Oba","doi":"10.1177/20584601251380870","DOIUrl":"10.1177/20584601251380870","url":null,"abstract":"<p><p>Dropped head syndrome, characterized by excessive flexion of the neck, frequently leads to significant impairment in quality of life. Among the various causes of this syndrome, some cases respond effectively to internal medicine. We report a case of a woman in her 70s who presented with dropped head syndrome and was finally diagnosed with hypothyroid myopathy limited to the extensor muscles of the neck. Cervical spine MRI at the initial examination indicated thyroid atrophy, increased subcutaneous fat, and a mild high signal in the right cervical extensor muscles on fat-suppressed T2-weighted images. Blood tests confirmed hypothyroidism. Treatment with levothyroxine improved the symptoms and normalized the blood test results. This case highlights the importance of careful evaluation of the thyroid gland and paravertebral muscles in cervical spine MRI. They can offer diagnostic clues for underlying the important causative role of thyroid disease in dropped head syndrome.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 9","pages":"20584601251380870"},"PeriodicalIF":1.0,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12446784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2025-09-10eCollection Date: 2025-09-01DOI: 10.1177/20584601251377911
Yang Shan Edmond Lim, Shuyi Guo, Zhuyi Rebekah Lee, Emma Choon Hwee Lee, Timothy Shao Ern Tan
{"title":"A visual compendium of teratomas and their diverse anatomical locations.","authors":"Yang Shan Edmond Lim, Shuyi Guo, Zhuyi Rebekah Lee, Emma Choon Hwee Lee, Timothy Shao Ern Tan","doi":"10.1177/20584601251377911","DOIUrl":"10.1177/20584601251377911","url":null,"abstract":"<p><p>Teratomas are a common type of germ cell tumours which may be benign or malignant. Benign mature teratomas are the most frequent subtype and typically show intralesional fat and calcifications within a cystic mass. Immature/malignant teratomas are usually larger with irregular solid components, coarse calcifications, small amounts of fat, and with or without necrosis or haemorrhage. Teratomas can manifest in various anatomical locations, particularly in the sacrococcygeal, gonadal, mediastinal, retroperitoneal, and intracranial regions. This article explores the imaging characteristics and diverse locations of teratomas as well as discusses about possible differential diagnoses to facilitate early detection and ensure prompt treatment.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 9","pages":"20584601251377911"},"PeriodicalIF":1.0,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12423518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2025-08-26eCollection Date: 2025-08-01DOI: 10.1177/20584601251367336
Aapo Inkiläinen, Börje Ljungberg, Lennart Blomqvist, Karin Strigård
{"title":"Addressing the need for predictive tools in postoperative abdominal wall complications after nephrectomy - Evaluation of a novel abdominal bulge grading system using computed tomography.","authors":"Aapo Inkiläinen, Börje Ljungberg, Lennart Blomqvist, Karin Strigård","doi":"10.1177/20584601251367336","DOIUrl":"10.1177/20584601251367336","url":null,"abstract":"<p><strong>Background: </strong>Abdominal bulging affects up to one-fourth of patients after flank incision, with half experiencing impaired quality of life. Identifying patients at risk for morbid bulge could improve preventive and supportive care.</p><p><strong>Purpose: </strong>To characterise muscular changes related to postoperative abdominal bulging and design a visual scoring system to grade bulge on postoperative CT scans.</p><p><strong>Material and methods: </strong>Patients treated with open partial nephrectomy via a flank incision between 2005 and 2016 at the University Hospital of Umeå were included. Pre- and postoperative CT scans of the first 50 consecutive patients were used to characterise imaging features of the postoperative abdominal wall. From these features, a four-tiered scoring system for abdominal bulge was designed. Two independent observers tested the system on CT scans from the 50 next patients. Inter-rater reliability was assessed using Fleiss' Kappa.</p><p><strong>Results: </strong>Common features of abdominal bulging were extracted and a four-tier visual score ranging from normal abdominal wall to severe bulge was developed. Among the patients, ∼70% had a normal abdominal wall, ∼25% had bulge score 1, ∼7% score 2, and ∼1% score 3. Inter-rater agreement was 73.5%, with Fleiss' Kappa 0.44.</p><p><strong>Conclusion: </strong>Features of bulge were reduced muscle thickness and ipsilateral gravitational slump affecting part or all of the lateral abdominal wall. The proposed scoring system demonstrated only moderate inter-rater reliability in this pilot setting. Further research on postoperative abdominal wall changes is needed before implementing imaging-based assessments in clinical care.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 8","pages":"20584601251367336"},"PeriodicalIF":1.0,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12381475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2025-07-30eCollection Date: 2025-07-01DOI: 10.1177/20584601251362322
Mathias Rosenfeldt Byriel, Torben Frøstrup Hansen, Hans Bjarke Rahr, Lars Henrik Jensen, Signe Timm, Jan Lindebjerg, Mazen Schnefeldt, Søren Rafael Rafaelsen
{"title":"MRI T1 relaxation time for evaluating early complete response to neoadjuvant treatment in rectal cancer: measurement at six weeks - a protocol article.","authors":"Mathias Rosenfeldt Byriel, Torben Frøstrup Hansen, Hans Bjarke Rahr, Lars Henrik Jensen, Signe Timm, Jan Lindebjerg, Mazen Schnefeldt, Søren Rafael Rafaelsen","doi":"10.1177/20584601251362322","DOIUrl":"10.1177/20584601251362322","url":null,"abstract":"<p><strong>Background: </strong>Management of rectal cancer requires accurate staging and treatment. Neoadjuvant chemoradiotherapy offers tumour size reduction and mitigation of the risk of local relapse. Patients with complete response to neoadjuvant treatment can be enclosed in watchful waiting (WW). Recent studies have explored magnetic resonance imaging (MRI) T1 relaxation time (T1RT) as a predictive biomarker for treatment response in rectal cancer. Preliminary findings indicate that lower T1RT correlates with pathologic complete response. However, inclusion of patients in WW remains unexplored.</p><p><strong>Purpose: </strong>This prospective study aims to investigate T1RT 6 weeks after neoadjuvant treatment and the ability to determine complete response.</p><p><strong>Material and methods: </strong>MRI scans are conducted on a 1.5 T MRI-unit. T1RT is measured at time of diagnosis and 6 weeks after neoadjuvant treatment. Experienced radiologists analyse T1RT using specialised software. Treatment decisions are made in multidisciplinary team conferences based on tumour staging. Endpoints include tumour visibility on MRI and endoscopy, along with histopathological analysis of surgical specimens. Statistical methods include <i>t</i> test and receiver operating characteristic curves. Sample size calculations showed we must enrol 76 participants to achieve a statistical power of 80% with an α = 0.05.</p><p><strong>Results: </strong>Data analysis begins in winter 2025. Results are planned to be submitted in spring 2026.</p><p><strong>Conclusion: </strong>The implications of this study extend to the potential refinement of treatment strategies, offering patients the prospect of improved outcomes and the potential avoidance of surgery-associated risks. We expect to find a lower relaxation time in fibrotic tissue compared to non-responsive cancerous tissue after 6 weeks.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 7","pages":"20584601251362322"},"PeriodicalIF":1.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12317158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Strangulated cholecystitis with imaging findings similar to those of gallbladder torsion: A case report.","authors":"Kazuya Okamura, Takuma Ito, Emi Ishibashi, Yoshiko Kanasaki, Koji Yuasa, Junji Iwasaki, Hideyuki Onuma","doi":"10.1177/20584601251363696","DOIUrl":"10.1177/20584601251363696","url":null,"abstract":"<p><p>Cholecystitis is a common disease, but the occurrence of gallbladder strangulation is extremely rare. Here, we report a case of an 88-year-old woman with strangulated cholecystitis caused by an intraperitoneal band. Computed tomography (CT) scan revealed a constriction of the gallbladder body and marked wall thickening at the fundus. Additionally, the finding suggested torsion at the constricted area, which we diagnosed as gallbladder torsion. Cholecystectomy was performed immediately, and the diagnosis was strangulated cholecystitis caused by a band. The imaging findings of strangulated cholecystitis are similar to gallbladder torsion, making it difficult to diagnose preoperatively. We will discuss the imaging findings of strangulated cholecystitis and gallbladder torsion.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 7","pages":"20584601251363696"},"PeriodicalIF":1.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12314225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of virtual monochromatic imaging using portal-venous phase dual-energy CT for detection of pulmonary embolism.","authors":"Hidetoshi Taguchi, Akihiro Imamura, Kotaro Sekiguchi, Hiroaki Okada, Hiroyuki Funatsu, Hideyuki Takano, Kojiro Suzuki","doi":"10.1177/20584601251360347","DOIUrl":"10.1177/20584601251360347","url":null,"abstract":"<p><strong>Background: </strong>As CT pulmonary angiography (CTPA) is not performed in routine contrast-enhanced CT, it is important to improve the accuracy of embolism detection from the portal-venous phase images that are generally obtained.</p><p><strong>Purpose: </strong>To assess the diagnostic performance of virtual monochromatic images (VMIs) obtained from portal phase dual-energy CT (PP-DECT) by qualitative and quantitative evaluation of contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) compared with those of CTPA.</p><p><strong>Material and methods: </strong>Included were 45 oncology patients who had been diagnosed with pulmonary embolism based on CTPA. Two radiologists evaluated conventional PP-DECT images and VMIs created from PP-DECT at 40, 55, 70, and 85 keV with the window width and level fixed at 400/70. The energy with the highest diagnostic accuracy was determined, and the image was re-evaluated under conditions where the window could be freely set. Quantitative evaluation was based on CNR and SNR.</p><p><strong>Results: </strong>Under the condition of fixed window width and level, the energy with the highest accuracy was 55 keV for both radiologists. When the window was set freely in the 55 keV image, accuracy rates were 96.0% and 96.3%; and were 98.5% and 98.1% when limited to the main pulmonary artery or lobar level. CNR and SNR were highest at 40 keV, and were similar to those of CTPA.</p><p><strong>Conclusion: </strong>Compared to original PP-DECT images, 55 keV images created from PP-DECT appear more useful for detecting pulmonary embolism.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 7","pages":"20584601251360347"},"PeriodicalIF":0.9,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of drug-coated balloon for repeated short-term restenosis of dialysis arteriovenous fistulas.","authors":"Takanori Maeda, Koji Kuroda, Makoto Takemoto, Wataru Fujimoto, Soichiro Yamashita, Junichi Imanishi, Masamichi Iwasaki, Takafumi Todoroki, Masanori Okuda","doi":"10.1177/20584601251352987","DOIUrl":"10.1177/20584601251352987","url":null,"abstract":"<p><strong>Background: </strong>Drug-coated balloons (DCB) are used for vascular access interventional therapy (VAIVT). However, few studies on patients with repeated short-term restenosis after VAIVT using a standard balloon (SB) have been reported, and the effect of DCB use on patency in these patients remains unclear.</p><p><strong>Purpose: </strong>This study aimed to evaluate the efficacy of DCB in patients with repeated short-term restenosis after VAIVT with SB.</p><p><strong>Materials and methods: </strong>This was a single-center retrospective study. We enrolled 50 consecutive patients who suffered two consecutive restenosis episodes within 6 months after VAIVT with SB. In the third session, patients were treated with DCB or SB. Target lesion revascularization (TLR) was evaluated for 1 year after the third session, with the primary endpoint being the TLR-free rate at 6 months after VAIVT.</p><p><strong>Results: </strong>At the third procedure, 24 patients were treated with DCB (DCB group), whereas 26 were treated with SB (SB group). The TLR-free rates at 6 months and 1-year were significantly higher in the DCB group than in the SB group (79.2% vs 26.9%, <i>p</i> < .001; and 41.7% vs 7.7%, <i>p</i> = .005). In the DCB group, a significant correlation was observed between the TLR duration from VAIVT with DCB and the prerestenosis duration before DCB treatment.</p><p><strong>Conclusions: </strong>Among patients with repeated short-term restenosis after VAIVT, DCB use significantly improved short-term patency compared with that after SB use. DCB may help extend the period between sessions, which are repeated in the short term, to an acceptable length.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 6","pages":"20584601251352987"},"PeriodicalIF":0.9,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12179460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144369662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A preliminary study on diffusion-weighted imaging with background suppression and maximum intensity projection for screening internal mammary lymph node metastasis of breast cancer.","authors":"Taiyo L Harada, Takayoshi Uematsu, Kazuaki Nakashima, Takashi Sugino, Seiichirou Nishimura, Tomomi Hayashi, Yukiko Tadokoro","doi":"10.1177/20584601251339017","DOIUrl":"10.1177/20584601251339017","url":null,"abstract":"<p><strong>Background: </strong>Internal mammary lymph node (IM) metastasis significantly affects prognosis. However, reports using imaging techniques have been limited. Diffusion-weighted imaging with background suppression and maximum intensity projection (DWIBS-MIP) is a sophisticated imaging method that emphasizes key signal areas such as tumors or lymph nodes in three-dimensional, providing a quick and comprehensive view immediately. Therefore, DWIBS-MIP can become a screening method for IM metastasis.</p><p><strong>Purpose: </strong>To investigates the usefulness of DWIBS-MIP for screening IM metastasis in patients undergoing preoperative breast MRI.</p><p><strong>Material and methods: </strong>Breast cancer patients with suspected IM metastasis from January 2017 to June 2024 were assessed. We evaluated the visibility and the size of IM metastasis, the long axis, short axis, and short-to-long axis (S/L) ratio of the biopsied lymph nodes at DWIBS-MIP. Patient's age, maximum diameter and hormonal status of primary cancer, breast cancer stage, the presence of axillary lymph node (Ax) metastasis, the location of the primary lesion were evaluated.</p><p><strong>Results: </strong>This study included 31 patients with IM metastasis and eight without IM metastasis. DWIBS-MIP exhibited a predictive value of 79.5% for screening IM metastasis. Between two groups, morphological characteristics of IM lymph nodes, including the long axis, short axis, and S/L ratio, demonstrated no significant differences. A higher proportion of Ax metastasis was possible in cases with IM metastasis. Other clinical data did not indicate significant differences.</p><p><strong>Conclusions: </strong>DWIBS-MIP provides an easy and effective assessment method for screening IM metastasis. The study indicates incorporating DWIBS-MIP into routine clinical practice can improve IM detection accuracy.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 6","pages":"20584601251339017"},"PeriodicalIF":0.9,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2025-05-22eCollection Date: 2025-05-01DOI: 10.1177/20584601251342312
Burak Günay, Muzaffer Savaş Tepe, Halis Harun Öztürk, Atakan Küskün, Murat Gençbay
{"title":"Pericoronary fat attenuation in stenotic and vulnerable coronary artery plaques: Implications for coronary artery disease and associated conditions.","authors":"Burak Günay, Muzaffer Savaş Tepe, Halis Harun Öztürk, Atakan Küskün, Murat Gençbay","doi":"10.1177/20584601251342312","DOIUrl":"10.1177/20584601251342312","url":null,"abstract":"<p><strong>Background: </strong>Pericoronary adipose tissue density (PCAT) is a parameter that quantifies inflammation and atherosclerosis around the coronary arteries.</p><p><strong>Purpose: </strong>To investigate the correlation between PCAT and plaque features, stenosis degrees in coronary arteries (LAD, RCA, Cx) with stenotic vulnerable plaques.</p><p><strong>Material and methods: </strong>A Retrospective study including 103 patients (64M, 39F) who underwent coronary computed tomography was retrospectively examined at a single center. PCAT and high-risk plaques were measured independently and compared to stenosis and coronary artery type. Adipose tissue attenuation, ranging from -180 to -25 HU, was measured along the plaque's length and in a 0.5-1 mm region around the perilesional coronary arteries.</p><p><strong>Results: </strong>The PCAT values increases with the degree of stenosis in the LAD, Cx, and RCA (r = 0.9161, <i>p</i> < .001; r = 0.9717, <i>p</i> < .001; r = 0.9315, <i>p</i> < .001, respectively). PCAT values demonstrate a positive pattern when plaque length increases in all coronary arteries (r = -0.6316, <i>p</i> < .001; r = -0.8825, <i>p</i> < .001; r = -0.7529, <i>p</i> < .001; LAD, Cx, RCA). PCAT values differed significantly based on plaque type in all coronary arteries. Calcified plaques showed statistically significant differences compared to both soft and mixed plaques (<i>p</i> < .05). Patients with positive remodeling had PCAT values of -69.43 (±8.76) HU, while cases without positive remodeling had PCAT values of -84.54 (±7.65) HU, indicating a significant difference (<i>p</i> < .05).</p><p><strong>Conclusion: </strong>The combined evaluation of plaque features, stenosis degree, and PCAT provides a more accurate prediction of possible acute coronary syndrome cases than analyzing stenosis degree alone.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 5","pages":"20584601251342312"},"PeriodicalIF":0.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12099116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}