Efficacy of drug-coated balloon for repeated short-term restenosis of dialysis arteriovenous fistulas.

IF 1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Acta radiologica open Pub Date : 2025-06-19 eCollection Date: 2025-06-01 DOI:10.1177/20584601251352987
Takanori Maeda, Koji Kuroda, Makoto Takemoto, Wataru Fujimoto, Soichiro Yamashita, Junichi Imanishi, Masamichi Iwasaki, Takafumi Todoroki, Masanori Okuda
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引用次数: 0

Abstract

Background: Drug-coated balloons (DCB) are used for vascular access interventional therapy (VAIVT). However, few studies on patients with repeated short-term restenosis after VAIVT using a standard balloon (SB) have been reported, and the effect of DCB use on patency in these patients remains unclear.

Purpose: This study aimed to evaluate the efficacy of DCB in patients with repeated short-term restenosis after VAIVT with SB.

Materials and methods: This was a single-center retrospective study. We enrolled 50 consecutive patients who suffered two consecutive restenosis episodes within 6 months after VAIVT with SB. In the third session, patients were treated with DCB or SB. Target lesion revascularization (TLR) was evaluated for 1 year after the third session, with the primary endpoint being the TLR-free rate at 6 months after VAIVT.

Results: At the third procedure, 24 patients were treated with DCB (DCB group), whereas 26 were treated with SB (SB group). The TLR-free rates at 6 months and 1-year were significantly higher in the DCB group than in the SB group (79.2% vs 26.9%, p < .001; and 41.7% vs 7.7%, p = .005). In the DCB group, a significant correlation was observed between the TLR duration from VAIVT with DCB and the prerestenosis duration before DCB treatment.

Conclusions: Among patients with repeated short-term restenosis after VAIVT, DCB use significantly improved short-term patency compared with that after SB use. DCB may help extend the period between sessions, which are repeated in the short term, to an acceptable length.

药物包被球囊治疗透析动静脉瘘反复短期再狭窄的疗效观察。
背景:药物包被气球(DCB)用于血管通路介入治疗(VAIVT)。然而,很少有研究报道使用标准球囊(SB)对VAIVT后反复出现短期再狭窄的患者,并且DCB对这些患者通畅的影响尚不清楚。目的:本研究旨在评价DCB对sbs VAIVT术后反复短期再狭窄患者的疗效。材料和方法:单中心回顾性研究。我们招募了50名连续患者,他们在VAIVT合并SB后6个月内连续发生两次再狭窄。在第三期,患者接受DCB或SB治疗。在第三期后的1年内评估靶病变血运重建(TLR),主要终点是VAIVT后6个月TLR的无害率。结果:第三道手术中,DCB组24例,SB组26例。DCB组6个月和1年tlr无自由基率显著高于SB组(79.2% vs 26.9%, p < 0.001;41.7% vs 7.7%, p = 0.005)。在DCB组中,从VAIVT到DCB的TLR持续时间与DCB治疗前的预狭窄持续时间之间存在显著相关性。结论:在VAIVT后反复出现短期再狭窄的患者中,与使用SB相比,使用DCB可显著改善短期通畅。DCB可以帮助延长会议之间的时间,这些会议在短期内重复,到一个可接受的长度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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