Acta radiologica open最新文献

{"title":"Computed tomography patterns and clinical outcomes of radiation pneumonitis in non-small-cell lung cancer patients.","authors":"Ji Hoon Choi, Hee Kang, Ji Su Lim, Ki-Nam Lee","doi":"10.1177/20584601241288502","DOIUrl":"https://doi.org/10.1177/20584601241288502","url":null,"abstract":"<p><strong>Background: </strong>Radiation pneumonitis (RP) is not an uncommon complication in lung cancer patients undergoing radiation therapy (RT) and symptomatic RP can affect their quality of life.</p><p><strong>Purpose: </strong>To investigate the CT findings of RP in non-small cell lung cancer (NSCLC) patients and their relationship with clinical outcomes.</p><p><strong>Materials and methods: </strong>We reviewed data from 240 NSCLC patients who underwent RT between 2014 and 2022. CT findings of RP were evaluated for parenchymal abnormalities and distribution, which were then classified into three patterns: localized pneumonia (LP), cryptogenic organizing pneumonia (COP), and acute interstitial pneumonia (AIP). Clinical outcomes of RP were evaluated based on Common Terminology Criteria for Adverse Events (CTCAE) grade.</p><p><strong>Results: </strong>Of the 153 patients, 135 developed RP. The most common pattern was LP (<i>n</i> = 78), followed by COP (<i>n</i> = 30) and AIP (<i>n</i> = 25). Among the three CT patterns, CTCAE grade and days between the start of RT and the onset of RP (RT-RP days) were statistically significantly different (<i>p</i> < 0.05). The patients with AIP patterns exhibited higher CTCAE grade, and fewer RT-RP days compared to those with non-AIP patterns (<i>p</i> < 0.05). In these patients, lung-to-lung metastasis and underlying interstitial lung abnormality were observed more frequently (<i>p</i> < 0.05). Underlying pulmonary fibrosis, the AIP pattern, and higher CT extent scores were more frequently observed in higher CTCAE grade group (<i>p</i> < 0.001). In multiple regression analysis, age, bilateral distribution, RT-RP days, and CT extent score ≥3 were independent predicting factors for higher CTCAE grade.</p><p><strong>Conclusions: </strong>RP in NSCLC patients can be classified into LP, COP, and AIP patterns and they exhibit different severities in clinical outcomes.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"13 10","pages":"20584601241288502"},"PeriodicalIF":0.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11459547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invasive trigeminal ganglioneuroma: A case report and review of the literature.","authors":"Rama Krishna Narra, Kavya Are, Parveen Nuzhat","doi":"10.1177/20584601241283780","DOIUrl":"https://doi.org/10.1177/20584601241283780","url":null,"abstract":"<p><p>Ganglioneuromas are rare tumors arising from retroperitoneal and posterior mediastinal sympathetic nerves. Intracranial trigeminal nerve ganglioneuromas are even more rare, with only seven cases reported to date. We present a case of a 65-year-old male with a right-sided throbbing headache type and blindness in his right eye. Magnetic resonance imaging revealed an ill-defined mass lesion in the middle-cranial fossa, with a few areas having a reduced apparent diffusion coefficient and multiple microhemorrhages. Piecemeal debulking of the tumor was achieved by performing a right-middle craniotomy via the pterionic and sub-temporal approach. The detected histological features matched those of a ganglioneuroma (maturing type) of the trigeminal nerve.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"13 9","pages":"20584601241283780"},"PeriodicalIF":0.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11384535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of primary osteosarcoma in the occipital bone: A relatively common tumor in an uncommon location.","authors":"Kezhou Xing, Guoli Ren, Shuning Liu, Chuanchen Zhang","doi":"10.1177/20584601241279134","DOIUrl":"10.1177/20584601241279134","url":null,"abstract":"<p><p>Osteosarcomas predominantly manifest in the long bones of the extremities, with rare occurrences in the skull. A case involving of a 53-year-old female who presented to the authors' hospital for examination due to dizziness was incidentally found to have an occipital bone mass, which was initially diagnosed as a benign tumor and did not receive sufficient attention. Two years later, owing to tumor enlargement, the patient underwent further evaluation at the same institution, which revealed evidence of occipital bone destruction. Pathological analysis confirmed the diagnosis of osteosarcoma. The patient underwent surgical resection followed by radiotherapy. Despite its infrequency and uncharacteristic initial presentation, skull osteosarcomas should not be overlooked.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"13 9","pages":"20584601241279134"},"PeriodicalIF":0.9,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142121156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To biopsy or not to biopsy adrenal mass: is that the question?","authors":"Edouard Purenne, Erika Cornu, Vincent Mezzarobba, Pauline Juttet, Sébastien Cimarelli, Emmanuel Watkin, Anne-Cécile Paepegaey","doi":"10.1177/20584601241269581","DOIUrl":"10.1177/20584601241269581","url":null,"abstract":"<p><p>The European Society of Endocrinology recommends surgical approach for suspicious adrenal mass with a limited role for adrenal biopsy. We report here a case of a patient with a 70 mm adrenal mass in whom adrenal biopsy avoided unnecessary adrenalectomy. An 80-year-old man was explored for a 67 × 41 mm suspect left adrenal tumor. Hormonal explorations were normal. 18F-FDG-PET/CT showed an increase in uptake of the adrenal mass (SUVmax: 44.6). As the diagnostic was uncertain, biopsy was performed. Pathology found T lymphocytic inflammatory infiltrate with CD4 phenotype without malignancy criteria. Simple close monitoring was decided in multidisciplinary meeting and with the patient's consent. At 1 and 3 months, CT and 18F-FDG-PET/CT showed a significant decrease in size and uptake of adrenal mass (40 × 20 mm and 19 × 10 mm and SUVmax 5.9 and 0.0). This report shows the interest of adrenal biopsy for well-selected cases to avoid unnecessary adrenal surgery.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"13 8","pages":"20584601241269581"},"PeriodicalIF":0.9,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11339733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemodynamic evaluation of intracranial arteriovenous malformations: Pre- and post-treatment 2D phase-contrast MRI measurements.","authors":"Maria Correia de Verdier, Elisabeth Ronne-Engström, Ljubisa Borota, Johan Wikström","doi":"10.1177/20584601241269608","DOIUrl":"10.1177/20584601241269608","url":null,"abstract":"<p><strong>Background: </strong>Hemodynamic changes are seen in the feeding arteries of arteriovenous malformations (AVMs). Phase-contrast MRI (PC-MRI) enables the acquisition of hemodynamic information from blood vessels. There is insufficient knowledge on which flow or velocity parameter best discriminates AVMs from healthy subjects.</p><p><strong>Purpose: </strong>To evaluate PC-MRI-measured flow and velocity in feeding arteries of AVMs before and, when possible, also after treatment and to compare these measurements to corresponding measurements in healthy controls.</p><p><strong>Materials and methods: </strong>Highest flow (HF), lowest flow (LF), mean flow (MF), peak systolic velocity (PSV), end-diastolic velocity (EDV), and mean velocity (MV) were measured in feeding arteries in patients with intracranial AVMs using 2D PC-MRI at 3 T. Measurements were compared to previously reported values in healthy individuals. Values in patients above the 95th percentile in the healthy cohort were categorized as pathological. Nidus volume was measured using 3D time-of-flight MR angiography.</p><p><strong>Results: </strong>Ten patients with diagnosed AVMs were examined with PC-MRI. Among these, three patients also underwent follow-up PC-MRI after treatment. Pathological velocities (PSV, EDV, and MV) were seen in all five subjects with a nidus larger or equal to 5.7 cm³, whereas pathological flow values were not seen in all, that is, pathologic HF in three, pathologic LF in two, and pathologic MF in two. After treatment, there was a decrease in flow and velocity (all measured parameters). After treatment, velocities (PSV, EDV, and MV) were no longer abnormal compared to healthy controls.</p><p><strong>Conclusion: </strong>Patients with a large AVM nidus show pathological velocities, but less consistent flow increases. Following treatment, velocities normalize.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"13 8","pages":"20584601241269608"},"PeriodicalIF":0.9,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11311173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141918217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipomatous pseudohypertrophy of the pancreas mimicking liposarcoma: A case report.","authors":"Tomomi Kamimura, Takashi Katsube, Takeshi Nishi, Yasunari Kawabata, Yoshitsugu Tajima, Asuka Araki, Yasushi Kaji","doi":"10.1177/20584601241259847","DOIUrl":"10.1177/20584601241259847","url":null,"abstract":"<p><p>Lipomatous pseudohypertrophy of the pancreas (LPH) is a rare disease in which the pancreatic parenchyma is replaced with mature adipose tissue. It is an idiopathic condition whose diagnosis is made based on histopathological analyses. Herein, we report the case of a 50-year-old male patient with a lipomatous mass in the head of the pancreas on computed tomography for close examination of a renal tumor. We suspected liposarcoma, and laparotomy was performed. However, histological analyses revealed LPH. Several imaging findings of LPH can enable a noninvasive diagnosis and help its clinical approach.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"13 8","pages":"20584601241259847"},"PeriodicalIF":0.9,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11292700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute on chronic pancreatitis affecting the ectopic pancreas located in the jejunal mesentery: A case report.","authors":"Kazuya Okamura, Emi Ishibashi, Kazumi Araki, Yoshiko Kanasaki, Koji Kodama, Akiyoshi Kanazawa, Hideyuki Onuma","doi":"10.1177/20584601241269617","DOIUrl":"10.1177/20584601241269617","url":null,"abstract":"<p><p>Ectopic pancreas within the mesentery is rare. In this case report, a 61-year-old man with an ectopic pancreas within the jejunal mesentery for over 20 years developed chronic pancreatitis that progressed to acute exacerbation. Our computed tomography (CT) performed for acute abdomen assessment suggested acute appendicitis or Meckel's diverticulitis. However, a CT scan taken 20 years ago revealed a structure indicative of an ectopic pancreas in the mesentery, and further imaging findings taken 10 and 4 years ago confirmed progression to chronic pancreatitis. Furthermore, we found a pancreatic stone confined in the luminal structure that corresponded to the main pancreatic duct; this stone eventually caused acute exacerbation. In summary, we report a case of mesenteric ectopic pancreas that showed typical findings of progression and acute exacerbation of chronic pancreatitis on CT.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"13 8","pages":"20584601241269617"},"PeriodicalIF":0.9,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging finding of multiple myeloma presenting as soft-tissue disease mimicking extrapleural space tumors: A case report.","authors":"Hee Kang","doi":"10.1177/20584601241246105","DOIUrl":"10.1177/20584601241246105","url":null,"abstract":"<p><p>Extramedullary involvement of multiple myeloma is an uncommon and aggressive condition characterized by proliferation of monoclonal plasma cells located outside the bone marrow. This report describes the imaging findings of a patient who presented with continuous soft-tissue disease on the ribs, suspected as extrapleural space tumors on chest CT. The patient was diagnosed with multiple myeloma through surgical biopsy of the tumor and bone marrow.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"13 6","pages":"20584601241246105"},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic resonance imaging in the second trimester as a complement to ultrasound for diagnosis of fetal anomalies.","authors":"Frida Cederlund, Ove Axelsson, Sara Desmond, Hashem Amini, Johan Wikström","doi":"10.1177/20584601241248820","DOIUrl":"10.1177/20584601241248820","url":null,"abstract":"<p><strong>Background: </strong>Fetal ultrasound has limitations, especially if the patient is obese or in cases with oligohydramnios. Magnetic resonance imaging (MRI) can then be used as a complement, but only few studies have focused on examinations in the second trimester.</p><p><strong>Purpose: </strong>To validate MRI as a complement to diagnose fetal anomalies in the second trimester.</p><p><strong>Material and methods: </strong>This retrospective study retrieved data from January 2008 to July 2012 from the Fetal Medicine Unit and Department of Radiology at Uppsala University Hospital. Ultrasound and MRI findings were reviewed in 121 fetuses in relation to the final diagnosis, including postpartum follow-up and autopsy results.</p><p><strong>Results: </strong>Of the 121 fetuses, 51 (42%) had a CNS anomaly and 70 (58%) a non-CNS anomaly diagnosed or suspected. MRI provided additional information in 21% of all cases without changing the management and revealed information that changed the management of the pregnancy in 13%. When a CNS anomaly was detected or suspected, the MRI provided additional information in 22% and changed the management in 10%. The corresponding figures for non-CNS cases were 21% and 16%, respectively. The proportion of cases with additional information that changed the management was especially high in patients with a BMI >30 kg/m² (25%) and in patients with oligohydramnios (38%). In five cases in category III, false-positive ultrasound findings were identified.</p><p><strong>Conclusions: </strong>MRI in the second trimester complements ultrasound and improves diagnosis of fetal CNS- and non-CNS anomalies especially when oligohydramnios or maternal obesity is present.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"13 5","pages":"20584601241248820"},"PeriodicalIF":0.0,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11088812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140913571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of transvaginal ultrasonography and hysterosalpingography in the detection of uterine cavity pathologies among infertile women.","authors":"Ifeanyi O Okonkwo, George U Eleje, Nworah J Obiechina, Joseph O Ugboaja, Chisolum O Okafor, Ikechukwu I Mbachu, Hillary I Obiagwu, Ayodele O Okwuosa, Daniel N Onwusulu, Chukwunwendu F Okeke, Chukwuemeka J Ofojebe, Chidinma C Okafor, Chukwudi A Ogabido, Chinedu L Olisa, Chigozie G Okafor","doi":"10.1177/20584601241252335","DOIUrl":"10.1177/20584601241252335","url":null,"abstract":"<p><strong>Background: </strong>Uterine cavity pathology may affect the endometrium or myometrium, resulting in distortion of the uterine cavity, and is responsible for 2%-5% of infertility. The methods for its assessment usually involve imaging modalities like pelvic ultrasonography, often transvaginal-(TVS), and hysterosalpingography-(HSG), with hysteroscopy-(HSC) as the gold standard. However, HSC is not readily available in resource-poor-settings.</p><p><strong>Purpose: </strong>To determine and compare the diagnostic accuracy of TVS and HSG in detecting uterine cavity pathology using HSC as a gold standard.</p><p><strong>Materials and methods: </strong>A cross-sectional analytical study of consenting infertile women for evaluation of the uterine cavity using transvaginal-ultrasonography, hysterosalpingogram, and hysteroscopy. The primary-outcome-measures were the sensitivity, specificity, and accuracy of TVS and HSG in detecting uterine cavity abnormalities using HSG as the gold standard.</p><p><strong>Results: </strong>Eighty-eight participants were analysed for this study. The lesions confirmed on HSC were intrauterine-adhesions (43.1%), endometrial polyps (14.8%), submucous fibroids (18.2%), intrauterine-septum (13.6%), and cavity distortion (14.8%). The overall sensitivity with TVS was 57.7%, with a specificity of 97.6%, a positive-predictive-value (PPV) of 88.2%, and a negative-predictive-value (NPV) of 88.2%, giving a percentage-accuracy of 88.2%. In comparison, HSG had a sensitivity of 72.1%, a specificity of 99.4%, a PPV of 97.4%, and an NPV of 92.0%, giving an overall accuracy of 92.9%. The detection rates of TVS and HSG in this category were: fibroids (97.7% vs 89.8%; <i>p</i> = .0004) and adhesions (73.9% vs 87.5%; <i>p</i> = .0002), respectively.</p><p><strong>Conclusion: </strong>HSG appears to be the superior modality for detection of obliterative uterine cavity pathologies, while TVS is better suited for myometrium and endometrial lesions.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"13 5","pages":"20584601241252335"},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11084983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140913570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}