Diagnostic yield and complications of CT-guided biopsy of lung lesions as a radiological outpatient clinic procedure.

IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Acta radiologica open Pub Date : 2025-03-20 eCollection Date: 2025-03-01 DOI:10.1177/20584601251326485
Katrine Bitsch Johansen, John Valtersson, Christian B Laursen, Bo Mussmann, Benjamin Rasmussen, Ole Graumann, Pia Iben Pietersen
{"title":"Diagnostic yield and complications of CT-guided biopsy of lung lesions as a radiological outpatient clinic procedure.","authors":"Katrine Bitsch Johansen, John Valtersson, Christian B Laursen, Bo Mussmann, Benjamin Rasmussen, Ole Graumann, Pia Iben Pietersen","doi":"10.1177/20584601251326485","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Computerized tomography-guided transthoracic needle biopsy (CT-TTNB) plays an important role in the diagnostic work-up of lung lesions. The literature reports varying results on complication rates, severity of complications, and diagnostic yield.</p><p><strong>Purpose: </strong>To evaluate CT-TTNB as a radiological outpatient clinic procedure and explore diagnostic yield and complication rates.</p><p><strong>Material and methods: </strong>Between January 2017 and October 2019, a total of 559 patients underwent CT-TTNB. Patient records and CT scans were retrospectively reviewed and patient characteristics, lesion characteristics, biopsy procedure, and per- and post-procedural complications, as well as pathological diagnosis, were registered.</p><p><strong>Results: </strong>Of 559 patients included, 511 had biopsies performed. Thereby, 48 biopsies (8.6%) were discontinued because of patient compliance issues and/or the occurrence of pneumothorax before the biopsy was performed. The overall pneumothorax rate was 49.2% (<i>n</i> = 275 of 559 patients). Insertion of a drainage catheter was needed in 85 of the 275 patients with pneumothorax. Parenchymal bleeding was seen in 26.5% of the patients and haemoptysis in 5.5%. No cases of bleeding or haemoptysis required intervention or admission. Small mean lesion size and increased distance from pleura to the lesion were associated with a higher occurrence of complications. A conclusive pathological diagnosis was obtained in 278 of 511 (54.4%) biopsies. No patients were re-admitted after the two-hour observational period in the radiological department.</p><p><strong>Conclusion: </strong>CT-TTNB as an outpatient clinic procedure is feasible but has a moderate diagnostic yield and relatively high complication rates for minor complications.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"14 3","pages":"20584601251326485"},"PeriodicalIF":0.9000,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926819/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta radiologica open","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/20584601251326485","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Computerized tomography-guided transthoracic needle biopsy (CT-TTNB) plays an important role in the diagnostic work-up of lung lesions. The literature reports varying results on complication rates, severity of complications, and diagnostic yield.

Purpose: To evaluate CT-TTNB as a radiological outpatient clinic procedure and explore diagnostic yield and complication rates.

Material and methods: Between January 2017 and October 2019, a total of 559 patients underwent CT-TTNB. Patient records and CT scans were retrospectively reviewed and patient characteristics, lesion characteristics, biopsy procedure, and per- and post-procedural complications, as well as pathological diagnosis, were registered.

Results: Of 559 patients included, 511 had biopsies performed. Thereby, 48 biopsies (8.6%) were discontinued because of patient compliance issues and/or the occurrence of pneumothorax before the biopsy was performed. The overall pneumothorax rate was 49.2% (n = 275 of 559 patients). Insertion of a drainage catheter was needed in 85 of the 275 patients with pneumothorax. Parenchymal bleeding was seen in 26.5% of the patients and haemoptysis in 5.5%. No cases of bleeding or haemoptysis required intervention or admission. Small mean lesion size and increased distance from pleura to the lesion were associated with a higher occurrence of complications. A conclusive pathological diagnosis was obtained in 278 of 511 (54.4%) biopsies. No patients were re-admitted after the two-hour observational period in the radiological department.

Conclusion: CT-TTNB as an outpatient clinic procedure is feasible but has a moderate diagnostic yield and relatively high complication rates for minor complications.

ct引导下肺病变活检作为放射门诊手术的诊断率和并发症。
背景:计算机断层扫描引导下的经胸穿刺活检(CT-TTNB)在肺部病变的诊断工作中起着重要的作用。文献报道了并发症发生率、并发症严重程度和诊断率的不同结果。目的:评价CT-TTNB作为放射学门诊手术的价值,探讨其诊断率和并发症发生率。材料与方法:2017年1月至2019年10月,共有559例患者接受了CT-TTNB。回顾性回顾患者记录和CT扫描,记录患者特征、病变特征、活检程序、术中和术后并发症以及病理诊断。结果:559例患者中,511例行活组织检查。因此,48例活检(8.6%)因患者依从性问题和/或在活检前发生气胸而停止。总气胸率为49.2% (n = 275 / 559例)。275例气胸患者中有85例需要置管引流。实质出血占26.5%,咯血占5.5%。无出血或咯血病例需要干预或入院。小的平均病灶大小和胸膜到病灶的距离增加与较高的并发症发生率相关。511例活检中有278例(54.4%)得到结论性病理诊断。在两个小时的观察期后,没有患者在放射科再次入院。结论:CT-TTNB作为门诊手术是可行的,但诊断率中等,轻微并发症的并发症发生率较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
审稿时长
12 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信