{"title":"Muscle volume evaluation using 3DCT for congenital clubfoot.","authors":"Masataka Kakihana, Yuki Tochigi, Satoru Ozeki, Tetsuya Jinno","doi":"10.1177/20584601211062084","DOIUrl":"https://doi.org/10.1177/20584601211062084","url":null,"abstract":"<p><strong>Background: </strong>In congenital clubfoot, the lower leg is very thin and the calf muscles are hypoplasic. However, there are few studies reporting real muscle volume.</p><p><strong>Purpose: </strong>The purpose of this study is to assay the muscle volume in congenital clubfoot using 3DCT and to quantify the degree of the hypoplasia.</p><p><strong>Material and methods: </strong>From January 2015 to December 2016, nine consecutive patients, seven male and two female, with unilateral congenital clubfeet were recruited for CT scans. Axial transverse sectional CT scans were acquired from the delineation of the fibular head to the tibial plafond. From the data, we rendered the entire muscle in 3D for muscle volume assay, and further segmented the posterior musculature for comparison between the normal and affected sides.</p><p><strong>Results: </strong>The whole muscle volume on the normal side was 291.23 cm<sup>3</sup> (181.23-593.49) and that on the affected side was 225.08 cm<sup>3</sup> (120.71-429.08), for an affected side to normal side ratio of 0.79 (0.72-0.9), which was significantly smaller (<i>p <</i> .01). Posterior muscle volume on the normal side was 175.81 cm<sup>3</sup> (103.72-376.32) and that on the affected side was 106.52 cm<sup>3</sup> (58.3-188.39). The ratio of posterior muscle to whole muscle on the normal side was 0.62 (0.46-0.75), and that on the affected side was 0.48 (0.4-0.55), such that the affected side was significantly smaller (<i>p <</i> .01).</p><p><strong>Conclusion: </strong>This study contributes quantitative data supporting the longstanding observations that the posterior calf muscles are significantly smaller on the affected side compared to the normal side in congenital clubfoot, and further underscores the importance of the extending the excursion of these muscles.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"10 11","pages":"20584601211062084"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/73/01/10.1177_20584601211062084.PMC8646796.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39817098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2021-12-03eCollection Date: 2021-11-01DOI: 10.1177/20584601211062059
Janni Jensen, Maja T Kristensen, Lene Bak, Søren S Kristensen, Ole Graumann
{"title":"MR arthrography of the shoulder; correlation with arthroscopy.","authors":"Janni Jensen, Maja T Kristensen, Lene Bak, Søren S Kristensen, Ole Graumann","doi":"10.1177/20584601211062059","DOIUrl":"https://doi.org/10.1177/20584601211062059","url":null,"abstract":"<p><strong>Background: </strong>Shoulder dislocation is a common injury, particularly in the younger population. Common long-term sequelae include pain, recurrence, and shoulder arthritis. Immediate and correct diagnosis following shoulder dislocation is key to achieving optimum outcomes. Although magnetic resonance arthrography (MRA) is frequently used for diagnosing shoulder instabilities, arthroscopy is still considered the gold standard.</p><p><strong>Purpose: </strong>This study aims to compare the diagnostic value of arthroscopy and MRA of the shoulder joint.</p><p><strong>Materials and methods: </strong>This retrospective study estimates the sensitivity and specificity of MRA of the shoulder. Data from patients who had undergone shoulder MRA and subsequent arthroscopy during a 5-year period were retrospectively collected. Sensitivity and specificity were calculated using the arthroscopic findings as the gold standard. Moreover, diagnostic accuracy was estimated using McNemar's test.</p><p><strong>Results: </strong>In total, 205 cases were included from which 372 pathological findings were uncovered during the arthroscopic procedures as opposed to 360 findings diagnosed from the MRA images. The glenoid labral tear was the most common finding reported by MRA and arthroscopy. For the detection of glenoid labral tears on MRA, the sensitivity was 0.955 but with eight missed lesions; the specificity was 0.679. Capsular tears, rotator cuff tears, and cartilage lesions proved the most difficult to correctly diagnose using MRA with sensitivities of 0.2, 0.346, and 0.366, respectively.</p><p><strong>Conclusions: </strong>With a sensitivity of 95%, MRA is a valuable diagnostic tool for assessing shoulder instabilities, particularly when diagnosing labral lesions, including bony and soft-tissue Bankart lesions. Sensitivities and specificities for other glenohumeral lesions are less convincing, however.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"10 11","pages":"20584601211062059"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/70/21/10.1177_20584601211062059.PMC8646798.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39817097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2021-11-30eCollection Date: 2021-11-01DOI: 10.1177/20584601211060707
Ivan Jambor, Alberto Martini, Ugo G Falagario, Otto Ettala, Pekka Taimen, Juha Knaapila, Kari T Syvänen, Aida Steiner, Janne Verho, Ileana M Perez, Harri Merisaari, Paula Vainio, Tarja Lamminen, Jani Saunavaara, Giuseppe Carrieri, Peter J Boström, Hannu J Aronen
{"title":"How to read biparametric MRI in men with a clinical suspicious of prostate cancer: Pictorial review for beginners with public access to imaging, clinical and histopathological database.","authors":"Ivan Jambor, Alberto Martini, Ugo G Falagario, Otto Ettala, Pekka Taimen, Juha Knaapila, Kari T Syvänen, Aida Steiner, Janne Verho, Ileana M Perez, Harri Merisaari, Paula Vainio, Tarja Lamminen, Jani Saunavaara, Giuseppe Carrieri, Peter J Boström, Hannu J Aronen","doi":"10.1177/20584601211060707","DOIUrl":"10.1177/20584601211060707","url":null,"abstract":"<p><p>Prostate Magnetic Resonance Imaging (MRI) is increasingly being used in men with a clinical suspicion of prostate cancer (PCa). Performing prostate MRI without the use of an intravenous contrast (IV) agent in men with a clinical suspicion of PCa can lead to reduced MRI scan time. Enabling a large array of different medical providers (from mid-level to specialized radiologists) to evaluate and potentially report prostate MRI in men with a clinical suspicion of PCa with a high accuracy could be one way to enable wide adoption of prostate MRI in men with a clinical suspicion of PCa. The aim of this pictorial review is to provide an insight into acquisition, quality control and reporting of prostate MRI performed without IV contrast agent in men with a clinical suspicion of PCa, aimed specifically at radiologists starting reporting prostate MRI, urologists, urology/radiology residents and mid-level medical providers without experience in reporting prostate MRI. Free public access (http://petiv.utu.fi/improd/and http://petiv.utu.fi/multiimprod/) to complete datasets of 161 and 338 men is provided. The imaging datasets are accompanied by clinical, laboratory and histopathological findings. Several topics are simplified in order to provide a solid base for the development of skills needed for an unsupervised review and potential reporting of prostate MRI in men with a clinical suspicion of PCa. The current review represents the first step towards enabling a large array of different medical providers to review and report accurately prostate MRI performed without IV contrast agent in men with a clinical suspicion of PCa.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"10 11","pages":"20584601211060707"},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/55/5d/10.1177_20584601211060707.PMC8638086.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39784225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2021-11-29eCollection Date: 2021-11-01DOI: 10.1177/20584601211053846
Mika Hirvonen, Juha-Jaakko Sinikumpu, Osmo Tervonen, Roberto Blanco Sequeiros
{"title":"Magnetic resonance imaging-guided biopsies in children.","authors":"Mika Hirvonen, Juha-Jaakko Sinikumpu, Osmo Tervonen, Roberto Blanco Sequeiros","doi":"10.1177/20584601211053846","DOIUrl":"https://doi.org/10.1177/20584601211053846","url":null,"abstract":"<p><strong>Background: </strong>Magnetic resonance imaging (MRI) is used far less as an imaging-guided method for percutaneous biopsies than computed tomography (CT) and ultrasound (US), despite its imaging benefits, particularly in children.</p><p><strong>Purpose: </strong>To evaluate the feasibility, accuracy and safety of MRI-guided biopsies in paediatric patient population.</p><p><strong>Material and methods: </strong>The retrospective study included 57 consecutive paediatric patients (<18 years old). A percutaneous core needle biopsy (PCNB) or trephine biopsy was performed in 53 cases, and an additional fine-needle aspiration biopsy (FNAB) in 26 cases. In 4 cases, a stand-alone FNAB was taken. Biopsies were performed with 0.23 T open and 1.5 T closed MRI scanners. Statistical methods used for confidence intervals and <i>p</i>-values were Wilson score method and chi-square test.</p><p><strong>Results: </strong>The overall diagnostic accuracy of histologic biopsy was 0.94, with sensitivity 0.82, specificity 1.00, positive predictive value (PPV) 1.00 and negative predictive value (NPV) 0.92. In histological bone biopsies, diagnostic accuracy was 0.96, with sensitivity 0.86, specificity 1.00, PPV 1.00 and NPV 0.94. The FNAB sample diagnosis was associated with the histological diagnosis in 79% of cases. There were no major primary complications and only a few late complications. After biopsy, 83% of the children were ambulatory in 6 h. Anti-inflammatory drugs and paracetamol provided satisfactory pain relief in 96% of the patients after biopsy. Most outpatients (71%) were discharged from hospital either on the same day or 1 day later.</p><p><strong>Conclusion: </strong>MRI is a technically feasible, accurate and safe guidance tool for performing percutaneous biopsies in children.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"10 11","pages":"20584601211053846"},"PeriodicalIF":0.0,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/de/9b/10.1177_20584601211053846.PMC8638078.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39784223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improved visualization of the chorda tympani nerve using ultra-high-resolution computed tomography.","authors":"Masahiro Fujiwara, Yoshiyuki Watanabe, Nobuo Kashiwagi, Yumi Ohta, Takashi Sato, Megumi Nishigaki, Noriyuki Tomiyama","doi":"10.1177/20584601211061444","DOIUrl":"https://doi.org/10.1177/20584601211061444","url":null,"abstract":"<p><strong>Background: </strong>Recognition of the anatomical course of the chorda tympani nerve (CTN) is important for preventing iatrogenic injuries during middle-ear surgery.</p><p><strong>Purpose: </strong>This study aims to compare visualization of the CTN using two computed tomography (CT) methods: conventional high-resolution CT (C-HRCT) and ultra-high-resolution CT (U-HRCT).</p><p><strong>Materials and methods: </strong>We performed a retrospective visual assessment of 59 CTNs in normal temporal bones of 54 consecutive patients who underwent both C-HRCT and U-HRCT. After dividing CTN into three anatomical segments (posterior canaliculus, tympanic segment, and anterior canaliculus), two neuroradiologists scored the visualizations on a four-point scale.</p><p><strong>Results: </strong>On C-HRCT, the visual scores of the posterior canaliculus, tympanic segment, and anterior canaliculus were 3.5 ± 0.7, 1.6 ± 0.6, and 3.1 ± 0.7, respectively. The respective values were significantly higher in all segments on U-HRCT: 3.9 ± 0.2, 2.4 ± 0.6, 3.5 ± 0.6 (<i>p</i> < 0.01). Although the difference in scores between methods was greatest for the tympanic segment, the visual score on U-HRCT was lower for the tympanic segment than for the anterior and posterior segments (<i>p</i> < 0.01).</p><p><strong>Conclusion: </strong>Ultra-high-resolution CT provides superior visualization of the CTN, especially the tympanic segment.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"10 11","pages":"20584601211061444"},"PeriodicalIF":0.0,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/52/76/10.1177_20584601211061444.PMC8637724.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39784226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2021-11-29eCollection Date: 2021-11-01DOI: 10.1177/20584601211060347
Lasse Hokkinen, Teemu Mäkelä, Sauli Savolainen, Marko Kangasniemi
{"title":"Computed tomography angiography-based deep learning method for treatment selection and infarct volume prediction in anterior cerebral circulation large vessel occlusion.","authors":"Lasse Hokkinen, Teemu Mäkelä, Sauli Savolainen, Marko Kangasniemi","doi":"10.1177/20584601211060347","DOIUrl":"https://doi.org/10.1177/20584601211060347","url":null,"abstract":"<p><strong>Background: </strong>Computed tomography perfusion (CTP) is the mainstay to determine possible eligibility for endovascular thrombectomy (EVT), but there is still a need for alternative methods in patient triage.</p><p><strong>Purpose: </strong>To study the ability of a computed tomography angiography (CTA)-based convolutional neural network (CNN) method in predicting final infarct volume in patients with large vessel occlusion successfully treated with endovascular therapy.</p><p><strong>Materials and methods: </strong>The accuracy of the CTA source image-based CNN in final infarct volume prediction was evaluated against follow-up CT or MR imaging in 89 patients with anterior circulation ischemic stroke successfully treated with EVT as defined by Thrombolysis in Cerebral Infarction category 2b or 3 using Pearson correlation coefficients and intraclass correlation coefficients. Convolutional neural network performance was also compared to a commercially available CTP-based software (RAPID, iSchemaView).</p><p><strong>Results: </strong>A correlation with final infarct volumes was found for both CNN and CTP-RAPID in patients presenting 6-24 h from symptom onset or last known well, with <i>r</i> = 0.67 (<i>p</i> < 0.001) and <i>r</i> = 0.82 (<i>p</i> < 0.001), respectively. Correlations with final infarct volumes in the early time window (0-6 h) were <i>r</i> = 0.43 (<i>p</i> = 0.002) for the CNN and <i>r</i> = 0.58 (<i>p</i> < 0.001) for CTP-RAPID. Compared to CTP-RAPID predictions, CNN estimated eligibility for thrombectomy according to ischemic core size in the late time window with a sensitivity of 0.38 and specificity of 0.89.</p><p><strong>Conclusion: </strong>A CTA-based CNN method had moderate correlation with final infarct volumes in the late time window in patients successfully treated with EVT.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"10 11","pages":"20584601211060347"},"PeriodicalIF":0.0,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/63/19/10.1177_20584601211060347.PMC8637731.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39784224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2021-11-18eCollection Date: 2021-10-01DOI: 10.1177/20584601211055389
Johannes Clemens Godt, Cathrine K Johansen, Anne Catrine T Martinsen, Anselm Schulz, Helga M Brøgger, Kristin Jensen, Arne Stray-Pedersen, Johann Baptist Dormagen
{"title":"Iterative reconstruction improves image quality and reduces radiation dose in trauma protocols; A human cadaver study.","authors":"Johannes Clemens Godt, Cathrine K Johansen, Anne Catrine T Martinsen, Anselm Schulz, Helga M Brøgger, Kristin Jensen, Arne Stray-Pedersen, Johann Baptist Dormagen","doi":"10.1177/20584601211055389","DOIUrl":"https://doi.org/10.1177/20584601211055389","url":null,"abstract":"<p><strong>Background: </strong>Radiation-related cancer risk is an object of concern in CT of trauma patients, as these represent a young population. Different radiation reducing methods, including iterative reconstruction (IR), and spilt bolus techniques have been introduced in the recent years in different large scale trauma centers.</p><p><strong>Purpose: </strong>To compare image quality in human cadaver exposed to thoracoabdominal computed tomography using IR and standard filtered back-projection (FBP) at different dose levels.</p><p><strong>Material and methods: </strong>Ten cadavers were scanned at full dose and a dose reduction in CTDIvol of 5 mGy (low dose 1) and 7.5 mGy (low dose 2) on a Siemens Definition Flash 128-slice computed tomography scanner. Low dose images were reconstructed with FBP and Sinogram affirmed iterative reconstruction (SAFIRE) level 2 and 4. Quantitative image quality was analyzed by comparison of contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR). Qualitative image quality was evaluated by use of visual grading regression (VGR) by four radiologists.</p><p><strong>Results: </strong>Readers preferred SAFIRE reconstructed images over FBP at a dose reduction of 40% (low dose 1) and 56% (low dose 2), with significant difference in overall impression of image quality. CNR and SNR showed significant improvement for images reconstructed with SAFIRE 2 and 4 compared to FBP at both low dose levels.</p><p><strong>Conclusions: </strong>Iterative image reconstruction, SAFIRE 2 and 4, resulted in equal or improved image quality at a dose reduction of up to 56% compared to full dose FBP and may be used a strong radiation reduction tool in the young trauma population.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"10 10","pages":"20584601211055389"},"PeriodicalIF":0.0,"publicationDate":"2021-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39941529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultra-short echo time magnetic resonance angiography using a modified signal targeting with alternative radio frequency spin labeling technique for detecting recanalized pulmonary arteriovenous malformation after coil embolization.","authors":"Kohei Hamamoto, Emiko Chiba, Noriko Oyama-Manabe, Hiroshi Shinmoto","doi":"10.1177/20584601211057671","DOIUrl":"https://doi.org/10.1177/20584601211057671","url":null,"abstract":"<p><p>Pulmonary arteriovenous malformation (PAVM) is a rare vascular anomaly, for which transcatheter embolization with metallic coils is the standard of care. Although detecting recanalization after embolotherapy is crucial, direct visualization of residual flow with computed tomography or magnetic resonance (MR) imaging is generally difficult due to metal artifacts. We present a case of recanalized PAVM after coil embolization detected by ultra-short echo time MR angiography using a modified signal targeting with an alternative radio frequency spin labeling technique.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"10 10","pages":"20584601211057671"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/90/88/10.1177_20584601211057671.PMC8564134.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39703942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2021-11-01eCollection Date: 2021-10-01DOI: 10.1177/20584601211050886
Maria Correia de Verdier, Elisabeth Ronne-Engström, Ljubisa Borota, Kristina Nilsson, Erik Blomquist, Johan Wikström
{"title":"Magnetic resonance imaging detected radiation-induced changes in patients with proton radiation-treated arteriovenous malformations.","authors":"Maria Correia de Verdier, Elisabeth Ronne-Engström, Ljubisa Borota, Kristina Nilsson, Erik Blomquist, Johan Wikström","doi":"10.1177/20584601211050886","DOIUrl":"https://doi.org/10.1177/20584601211050886","url":null,"abstract":"<p><strong>Background: </strong>Treatment of intracranial arteriovenous malformations (AVMs) includes surgery, radiation therapy, endovascular occlusion, or a combination. Proton radiation therapy enables very focused radiation, minimizing dose to the surrounding brain.</p><p><strong>Purpose: </strong>To evaluate the presence of radiation-induced changes on post-treatment MRI in patients with AVMs treated with proton radiation and to compare these with development of symptoms and nidus obliteration.</p><p><strong>Material and methods: </strong>Retrospective review of pre- and post-treatment digital subtraction angiography and MRI and medical records in 30 patients with AVMs treated with proton radiation. Patients were treated with two or five fractions; total radiation dose was 20-35 physical Gy. Vasogenic edema (minimal, perinidal, or severe), contrast enhancement (minimal or annular), cavitation and nidus obliteration (total, partial, or none) were assessed.</p><p><strong>Results: </strong>26 of 30 patients (87%) developed MRI changes. Vasogenic edema was seen in 25 of 30 (83%), abnormal contrast enhancement in 18 of 26 (69%) and cavitation in 5 of 30 (17%). Time from treatment to appearance of MRI changes varied between 5 and 25 months (median 7, mean 10). Seven patients developed new or deteriorating symptoms that required treatment with corticosteroids; all these patients had extensive MRI changes (severe vasogenic edema and annular contrast enhancement). Not all patients with extensive MRI changes developed symptoms. We found no relation between MRI changes and nidus obliteration.</p><p><strong>Conclusion: </strong>Radiation-induced MRI changes are seen in a majority of patients after proton radiation treatment of AVMs. Extensive MRI changes are associated with new or deteriorating symptoms.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"10 10","pages":"20584601211050886"},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39710117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2021-10-03eCollection Date: 2021-08-01DOI: 10.1177/20584601211038721
Elena Marín-Díez, Marta Drake-Pérez, Natalia Valle-San Román, Víctor Manuel Mora Cuesta, Miguel Ángel Hernández-Hernández, Enrique Marco de Lucas
{"title":"Imaging findings of neurologic complications in lung transplantation: Review of a 9-year cohort.","authors":"Elena Marín-Díez, Marta Drake-Pérez, Natalia Valle-San Román, Víctor Manuel Mora Cuesta, Miguel Ángel Hernández-Hernández, Enrique Marco de Lucas","doi":"10.1177/20584601211038721","DOIUrl":"https://doi.org/10.1177/20584601211038721","url":null,"abstract":"<p><strong>Background: </strong>Lung transplantation (LT) requires complex multidisciplinary organization and constitutes a therapeutic option and a life-saving procedure. Although the number of lung recipients continues to increase, neurological complications and death rates following lung transplantation are still higher than desirable.</p><p><strong>Purpose: </strong>This study aims to analyse the neuroimaging findings in a cohort of adult patients with LT.</p><p><strong>Material and methods: </strong>A retrospective cohort study of all lung transplant recipients (344 patients: 205 men and 139 women) at a single institution from January 2011 to January 2020. The collected data included demographic features, clinical data and evaluation of the imaging findings. We also recorded the date of neurological complication(s) and the underlying disease motivating lung transplantation.</p><p><strong>Results: </strong>We found an elevated rate of neuroimaging findings in patients following LT with 32.6% of positive studies. In our cohort, the average time after LT to a neurological complication was 4.9 months post-transplant. Encephalopathy, critical illness polyneuropathy and stroke, in that order, were the most frequent neurological complications. Structural abnormalities in brain imaging were more often detected using MRI than CT for indications of encephalopathy and seizures.</p><p><strong>Conclusions: </strong>LT recipients constitute an especially vulnerable group that needs close surveillance, mainly during the early post-transplant period.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":"10 8","pages":"20584601211038721"},"PeriodicalIF":0.0,"publicationDate":"2021-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39505620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}