{"title":"MRI interobserver reliability in rectal tumor angulation","authors":"M. Pedersen, P. Otto, H. Precht, S. Rafaelsen","doi":"10.1177/20584601221081292","DOIUrl":"https://doi.org/10.1177/20584601221081292","url":null,"abstract":"Background When rectal tumors are examined using magnetic resonance imaging (MRI) the perpendicular angulation of the axial T2-weighted image to the tumor axis is essential for a correct measure of the shortest distance between tumor and mesorectal facia. Purpose The purpose of this study was to determine the interobserver variability in rectal tumor angulation between a radiologist and a radiographer. Material and Methods Two observers performed the angulation independently. All MRI examinations were performed using an MRI 1.5 Tesla unit. A Bland–Altman plot was used to assess the interobserver variance and Intraclass correlation coefficient (ICC) statistic was used to assess the interobserver reliability. Results MRI was performed in 55 patients with rectal cancer during a one-year period (25 (45.5%) women and 30 (54.5%) men). The median age was 71 years (range 46–87 years). The rectal tumor mean length was 3.9 cm. The interobserver reliability was good (ICC = 0.83, 95% confidence interval 0.72–0.90). Conclusion Radiographers receiving training will be able to perform MRI rectal tumor angulation.","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48743110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tahir M Shakir, Liang Fengli, Guo Chenguang, N. Chen, Ming Zhang, Mai Shaohui
{"title":"1H-MR spectroscopy in grading of cerebral glioma: A new view point, MRS image quality assessment","authors":"Tahir M Shakir, Liang Fengli, Guo Chenguang, N. Chen, Ming Zhang, Mai Shaohui","doi":"10.1177/20584601221077068","DOIUrl":"https://doi.org/10.1177/20584601221077068","url":null,"abstract":"Background Noninvasive preoperative prediction of histological grading is essential for clinical management of cerebral glioma. Purpose This study aimed to investigate the association between the image quality assessment of 1H magnetic resonance spectroscopy and accurate grading of glioma. Materials and Methods 98 glioma patients confirmed by pathology were retrospectively recruited in this single-center study. All patients underwent 1H-MRS examination at 3.0T before surgery. According to WHO standards, all cases were divided into two groups: low-grade glioma (grade I and II, 48 cases) and high-grade glioma (grades III and IV, 50 cases). The metabolite ratios in both grades were calculated before and after image quality assessment. The area under the receiver operating characteristic (ROC) curve was used to evaluate the capacity of each ratio in glioma grading. Results The Cho/Cr, Cho/NAA and NAA/Cr metabolite ratios had certain differences in each glioma group before and after MRS image quality assessment. In the low-grade glioma group, there was a dramatic difference in the Cho/Cr ratio before and after image quality assessment (p = 0.011). After MRS image quality assessment, the accuracy of glioma grading was significantly improved. The Cho/Cr ratio with 83.3% sensitivity and 93.7% specificity is the best index of glioma grading, with the optimal cutoff value of the Cho/Cr ratio being 3.72. Conclusion The image quality of MRS does affect the metabolite ratios and the results of glioma grading. MRS image quality assessment can observably improve the accuracy rate of glioma grading. The Cho/Cr ratio has the best diagnostic performance in differentiating high-grade from low-grade glioma.","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46616969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Matsuda, Shunsuke Kobayashi, O. Hasegawa, K. Yoshida, H. Kubo, Y. Ugawa, K. Kanai
{"title":"Subclinical involvement of the trunk muscles in idiopathic inflammatory myopathies","authors":"N. Matsuda, Shunsuke Kobayashi, O. Hasegawa, K. Yoshida, H. Kubo, Y. Ugawa, K. Kanai","doi":"10.1177/20584601221075796","DOIUrl":"https://doi.org/10.1177/20584601221075796","url":null,"abstract":"Background Whole-body magnetic resonance imaging (WB-MRI) is a useful tool for revealing the disease-specific distribution of affected muscles and clinically asymptomatic muscle involvements in idiopathic inflammatory myopathies (IIMs). Purpose To examine inflammatory changes in the systemic skeletal muscles, including the thoracoabdominal trunk, in IIMs using WB-MRI. Material and Methods We prospectively obtained WB-MRI axial images from 10 patients with IIMs, including antisynthetase syndrome (ASS), immune-mediated necrotizing myopathy (IMNM), sporadic inclusion body myositis, and myopathy associated with antimitochondrial antibody. We evaluated 108 systemic skeletal muscles in short-tau inversion recovery (STIR) images and rated changes in signal intensity using a semiquantitative scale. Correlations between STIR sum score, peak creatine kinase (CK) and muscle strength were examined. We also investigated the correlation between STIR sum score within the thoracoabdominal trunk and forced vital capacity. Results High STIR signal changes were frequently identified in asymptomatic and routinely unexamined muscles. Thoracoabdominal trunk muscles were frequently involved in ASS and IMNM. Peak CK was positively correlated with the STIR sum score (R2 = 0.62, p < .01). There was no significant correlation between the STIR sum score within the thoracoabdominal trunk and forced vital capacity. Conclusion WB-MRI can detect subclinical muscle inflammation in the systemic muscles including the trunk muscles. STIR sum score is positively correlated with serum peak CK level; therefore, it could be a biomarker of overall muscle inflammation.","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43398831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Geographical variations in the use of outpatient diagnostic imaging in Norway 2019","authors":"B. Hofmann, A. M. Gransjøen","doi":"10.1177/20584601221074561","DOIUrl":"https://doi.org/10.1177/20584601221074561","url":null,"abstract":"Background Geographical variations in the use of outpatient imaging can reveal inappropriate use of radiological services. Knowledge about these variations is crucial in the strive for appropriate and improved services. Purpose To investigate the geographical variations in outpatient diagnostic imaging and analyze variations for main groups of examinations and for specific examinations. Material and methods Data on outpatient radiological procedures registered at the Norwegian Health Economics Administration in Norway for 2019 were accessed with county-based population rates for age adjustment accessed through Statistics Norway. Age-adjusted rates were used to calculate high/low ratios, means, standard deviations, and coefficients of variation were calculated per 10,000 inhabitants. Results There is high geographical variation for PET/CT and PET/MRI and moderate variation for neuroradiological outpatient examinations in Norway in 2019. Variations for the musculoskeletal systems and of thorax, abdomen, and vessels are almost 50%. We find high high-to-low ratios in CT—face (9.7), MRI—elbow joint (8.5), CT of the neck, thorax, abdomen, and pelvis (6.5) as well as MRI—prostate (6.2). Comparing with data from 2012–5, we find a reduction in variation for some examinations, such as MRI of the hip and MRI of the entire spine, and an increase in variations for others, such as CT of the face and MRI of the elbow joint. Conclusion Despite much attention to the problem, we demonstrate substantial variations in radiological services in Norway raising concern with respect to appropriateness, quality of care, equity, and justice. The findings provide important input for quality improvement in radiological services.","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45036039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chest imaging in pregnant patients with COVID-19: Recommendations, justification, and optimization","authors":"A. Nair, S. Ramanathan, P. Venugopalan","doi":"10.1177/20584601221077394","DOIUrl":"https://doi.org/10.1177/20584601221077394","url":null,"abstract":"Evaluation of COVID-19 related complication is challenging in pregnancy, due to concerns about ionizing radiation risk to mother and the fetus. Although there are instances when diagnostic imaging is clinically warranted for COVID-19 evaluation despite the minimal risks of radiation exposure, often there are concerns raised by the patients and sometimes by the attending physicians. This article reviews the current recommendations on indications of chest imaging in pregnant patients with COVID-19, the dose optimization strategies, and the risks related to imaging exposure during pregnancy. In clinical practice, these imaging strategies are key in addressing the complex obstetrical complications associated with COVID-19 pneumonia.","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47922985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Matsusue, Chie Inoue, S. Tabuchi, H. Yoshioka, Yuichiro Nagao, Kensuke Matsumoto, Kazuhiko Nakamura, S. Fujii
{"title":"Advanced magnetic resonance imaging findings of cerebellar hemangioblastomas: A report of three cases and a literature review","authors":"E. Matsusue, Chie Inoue, S. Tabuchi, H. Yoshioka, Yuichiro Nagao, Kensuke Matsumoto, Kazuhiko Nakamura, S. Fujii","doi":"10.1177/20584601221077074","DOIUrl":"https://doi.org/10.1177/20584601221077074","url":null,"abstract":"On conventional magnetic resonance imaging (MRI), hemangioblastomas typically appear as mural nodules with an adjacent surrounding cyst or a solid mass in the cerebellum. However, hemangioblastomas sometimes cannot be reliably distinguished using this imaging technique from other tumors, especially pilocytic astrocytomas and metastatic tumors, because of their similar imaging findings and locations. Herein, we report three cases of cerebellar hemangioblastomas and review their findings on conventional and advanced MRI, including diffusion-weighted imaging (DWI), dynamic susceptibility-weighted contrast-enhanced perfusion-weighted imaging (DSC-PWI), and magnetic resonance spectroscopy (MRS). Solid contrast-enhanced lesions of hemangioblastomas showed increased apparent diffusion coefficient values on DWI, increased relative cerebral blood volume ratio on DSC-PWI, and high lipid/lactate peak on MRS. Therefore, advanced MRI techniques can be helpful in understanding the pathological and metabolic changes of hemangioblastomas and may be useful for their characterization.","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47537717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2022-01-29eCollection Date: 2022-01-01DOI: 10.1177/20584601211072279
Ibrahim Hadadi, William Rae, Jillian Clarke, Mark McEntee, Ernest Ekpo
{"title":"Breast cancer detection across dense and non-dense breasts: Markers of diagnostic confidence and efficacy.","authors":"Ibrahim Hadadi, William Rae, Jillian Clarke, Mark McEntee, Ernest Ekpo","doi":"10.1177/20584601211072279","DOIUrl":"https://doi.org/10.1177/20584601211072279","url":null,"abstract":"<p><strong>Background: </strong>The impact of radiologists' characteristics has become a major focus of recent research. However, the markers of diagnostic efficacy and confidence in dense and non-dense breasts are poorly understood.</p><p><strong>Purpose: </strong>This study aims to assess the relationship between radiologists' characteristics and diagnostic performance across dense and non-dense breasts.</p><p><strong>Materials and methods: </strong>Radiologists specialising in breast imaging (<i>n</i> = 128) who had 0.5-40 (13±10.6) years of experience reading mammograms were recruited. Participants independently interpreted a test set containing 60 digital mammograms (40 normal and 20 abnormal) with similarly distributed breast densities. Diagnostic performance measures were analysed via Jamovi software (version 1.6.22).</p><p><strong>Results: </strong>In dense breasts, breast-imaging fellowship completion significantly improved specificity (<i>p</i> = 0.004), location sensitivity (<i>p</i> = 0.01) and the area under the curve (AUC) of the receiver operating characteristic (<i>p</i> = 0.03). Only participation in BreastScreen reading significantly improved all performance metrics: specificity (<i>p</i> = 0.04), sensitivity (<i>p</i> = 0.005), location sensitivity (<i>p</i> < 0.001) and AUC (<i>p</i> < 0.001). Reading > 100 mammograms weekly significantly improved sensitivity (<i>p</i> = 0.03), location sensitivity (<i>p</i> = 0.001), and AUC (<i>p</i> = 0.03).In non-dense breasts, breast fellowship completion significantly improved sensitivity (<i>p</i> = 0.02), location sensitivity (<i>p</i> = 0.04) and AUC (<i>p</i> = 0.002). Participation in BreastScreen reading and reading > 100 mammograms weekly significantly improved only sensitivity (<i>p</i> = 0.002 and <i>p</i> = 0.003, respectively) and location sensitivity (<i>p</i> < 0.001 and <i>p</i> < 0.001, respectively).</p><p><strong>Conclusion: </strong>Participating in screening programs, breast fellowships and reading > 100 mammograms weekly are important indicators of the diagnostic performance of radiologists across dense and non-dense breasts. In dense breasts, optimal performance resulted from participation in a breast screening program.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/97/ce/10.1177_20584601211072279.PMC8801646.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39744495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2022-01-21eCollection Date: 2022-01-01DOI: 10.1177/20584601211072281
Jonas Liefke, Katarina Steding-Ehrenborg, Daniel Asgeirsson, David Nordlund, Sascha Kopic, Eva Morsing, Erik Hedström
{"title":"Non-contrast-enhanced magnetic resonance imaging can be used to assess renal cortical and medullary volumes-A validation study.","authors":"Jonas Liefke, Katarina Steding-Ehrenborg, Daniel Asgeirsson, David Nordlund, Sascha Kopic, Eva Morsing, Erik Hedström","doi":"10.1177/20584601211072281","DOIUrl":"https://doi.org/10.1177/20584601211072281","url":null,"abstract":"<p><strong>Background: </strong>Magnetic resonance imaging (MRI) biomarkers can diagnose and prognosticate kidney disease. Renal volume validation studies are however scarce, and measurements are limited by use of contrast agent or advanced post-processing.</p><p><strong>Purpose: </strong>To validate a widely available non-contrast-enhanced MRI method for quantification of renal cortical and medullary volumes in pigs; investigate observer variability of cortical and medullary volumes in humans; and present reference values for renal cortical and medullary volumes in adolescents.</p><p><strong>Materials and methods: </strong>Cortical and medullary volumes were quantified from transaxial in-vivo water-excited MR images in six pigs and 15 healthy adolescents (13-16years). Pig kidneys were excised, and renal cortex and medulla were separately quantified by the water displacement method. Both limits of agreement by the Bland-Altman method and reference ranges are presented as 2.5-97.5 percentiles.</p><p><strong>Results: </strong>Agreement between MRI and ex-vivo quantification were -7 mL (-10-0 mL) for total parenchyma, -4 mL (-9-3 mL) for cortex, and -2 mL (-7-2 mL) for medulla. Intraobserver variability for pig and human kidneys were <5% for total parenchyma, cortex, and medulla. Interobserver variability for both pig and human kidneys were ≤4% for total parenchyma and cortex, and 6% and 12% for medulla. Reference ranges indexed for body surface area and sex were 54-103 mL/m<sup>2</sup> (boys) and 56-103 mL/m<sup>2</sup> (girls) for total parenchyma, 39-62 mL/m<sup>2</sup> and 36-68 mL/m<sup>2</sup> for cortex, and 16-45 mL/m<sup>2</sup> and 17-42 mL/m<sup>2</sup> for medulla.</p><p><strong>Conclusion: </strong>The proposed widely available non-contrast-enhanced MRI method can quantify cortical and medullary renal volumes and can be directly implemented clinically.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39749475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2022-01-21eCollection Date: 2022-01-01DOI: 10.1177/20584601211072280
Rituparna Saha, David Ryan, Emer Hanrahan, Jonathan D Dodd
{"title":"Early detection of recurrent lung cancer: Enhancing-nodule in post-radiation fibrosis.","authors":"Rituparna Saha, David Ryan, Emer Hanrahan, Jonathan D Dodd","doi":"10.1177/20584601211072280","DOIUrl":"https://doi.org/10.1177/20584601211072280","url":null,"abstract":"<p><p>Early detection of lung cancer recurrence on imaging is critical for better clinical prognosis. The 'enhancing nodule in post-radiation fibrosis sign' is an important sign which helps detect recurrent lung cancer early on CT chest.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/62/d2/10.1177_20584601211072280.PMC8785316.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39861943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologica openPub Date : 2022-01-19eCollection Date: 2022-01-01DOI: 10.1177/20584601211073864
Hans-Martin Thieß, Keno K Bressem, Lisa Adams, Georg Böning, Janis L Vahldiek, Stefan M Niehues
{"title":"Do submillisievert-chest CT protocols impact diagnostic quality in suspected COVID-19 patients?","authors":"Hans-Martin Thieß, Keno K Bressem, Lisa Adams, Georg Böning, Janis L Vahldiek, Stefan M Niehues","doi":"10.1177/20584601211073864","DOIUrl":"https://doi.org/10.1177/20584601211073864","url":null,"abstract":"<p><strong>Background: </strong>During the ongoing global SARS-CoV-2 pandemic, there is a high demand for quick and reliable methods for early identification of infected patients. Due to its widespread availability, chest-CT is commonly used to detect early pulmonary manifestations and for follow-ups.</p><p><strong>Purpose: </strong>This study aims to analyze image quality and reproducibility of readings of scans using low-dose chest CT protocols in patients suspected of SARS-CoV-2 infection.</p><p><strong>Materials and methods: </strong>Two radiologists retrospectively analyzed 100 low-dose chest CT scans of patients suspected of SARS-CoV-2 infection using two protocols on devices from two vendors regarding image quality based on a Likert scale. After 3 weeks, quality ratings were repeated to allow for analysis of intra-reader in addition to the inter-reader agreement. Furthermore, radiation dose and presence as well as distribution of radiological features were noted.</p><p><strong>Results: </strong>The exams' effective radiation doses were in median in the submillisievert range (median of 0.53 mSv, IQR: 0.35 mSv). While most scans were rated as being of optimal quality, 38% of scans were scored as suboptimal, yet only one scan was non-diagnostic. Inter-reader and intra-reader reliability showed almost perfect agreement with Cohen's kappa of 0.82 and 0.87.</p><p><strong>Conclusion: </strong>Overall, in this study, we present two protocols for submillisievert low-dose chest CT demonstrating appropriate or better image quality with almost perfect inter-reader and intra-reader agreement in patients suspected of SARS-CoV-2 infection.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39749912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}