{"title":"Remerciements aux relecteurs","authors":"","doi":"10.1016/S1877-0320(24)00411-1","DOIUrl":"10.1016/S1877-0320(24)00411-1","url":null,"abstract":"","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"64 6","pages":"Article 104190"},"PeriodicalIF":0.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142572705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Pouessel , P. Beaumont , E. Capelli , V. Cordebar , P. Couratier , A. Deschildre , A. Doc , S. Dufay , S. Glasson , V. Grandjean-Ceccon , C. Huss , A. Jonquières , L. Lepigeon , M. Lorenzi , B. Moltrecht , G. Perole , J.-M. Rame , N. Tajan , A.-L. Vincent , C. Lapeyre-Santos
{"title":"Rhinite allergique de l’enfant : étude clinique et évaluation de la qualité de vie avant et après traitement selon l’âge","authors":"S. Mezri , C. Ben Ammar , S. Mhamdi , A. Khemaies","doi":"10.1016/j.reval.2024.104175","DOIUrl":"10.1016/j.reval.2024.104175","url":null,"abstract":"<div><h3>Aim</h3><div>This study aims to investigate the characteristics of allergic rhinitis in children and evaluate the impact of treatment on their quality of life, stratified by age.</div></div><div><h3>Methods</h3><div>A prospective descriptive study was conducted on children aged 4 to 16 years who were diagnosed with allergic rhinitis for the first time at the beginning of the study. The study population was divided into two age groups: group 1 (4–12 years) and group 2 (12–16 years). The quality of life before and after 6 months of treatment was assessed using the Juniper Allergic Rhinoconjunctivitis Quality of Life Test (RQLQ) and the ARIA classification as endpoints.</div></div><div><h3>Results</h3><div>The study included 100 patients, 58 of whom were male, with a mean age of 9<!--> <!-->±<!--> <!-->3.3 years. Prior to treatment, 79 children had an overall score of 4 or higher, indicating they were “rather to extremely annoyed”. Children in group 1 reported nasal discomfort as their main complaint, with a score of 5.05 indicating they were “very annoyed”. Children in group 2 reported emotional impact as their main complaint, with a mean score of 4.54 indicating they were “rather to very annoyed”. Children with asthma had a higher RQLQ score than those without (<em>P</em> <!--><<!--> <!-->0.0001). Following six months of treatment, we observed a statistically significant improvement in ARIA classification and quality of life scores. The overall RQLQ score decreased from 3.82 to 1.79 for group 1 and from 3.74 to 1.73 for group 2. Logistic regression revealed that poor compliance and persistent allergen exposure were the main factors contributing to poor therapeutic control (odds ratio of 57 and 46, respectively).</div></div><div><h3>Conclusion</h3><div>This conclusion is based on objective evidence and avoids biased language. To improve management, it is recommended that quality of life tests for children treated for allergic rhinitis to be generalized. The field still lacks proper codification. No changes were made to the original content.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 2","pages":"Article 104175"},"PeriodicalIF":0.3,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142555064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Des formes alternatives à l’adrénaline injectable pour le traitement de l’anaphylaxie : de réelles innovations bientôt disponibles ?","authors":"G. Pouessel , C. Neukirch","doi":"10.1016/j.reval.2024.104172","DOIUrl":"10.1016/j.reval.2024.104172","url":null,"abstract":"","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 2","pages":"Article 104172"},"PeriodicalIF":0.3,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Sainte-Laudy , M. Cogné , J. Goret , J.C. Lecron , G. Kanny , T. Tabary , O. Barbier , E. Bellet , S. Guez , F. Lavaud , Y. Meunier , P.M. Mertes , C. Mouton , R. Stenger , F. Touraine
{"title":"Place du test d’activation des basophiles dans le diagnostic de l’allergie aux curares. Étude immunologique multicentrique","authors":"J. Sainte-Laudy , M. Cogné , J. Goret , J.C. Lecron , G. Kanny , T. Tabary , O. Barbier , E. Bellet , S. Guez , F. Lavaud , Y. Meunier , P.M. Mertes , C. Mouton , R. Stenger , F. Touraine","doi":"10.1016/j.reval.2024.104171","DOIUrl":"10.1016/j.reval.2024.104171","url":null,"abstract":"<div><h3>Aim of the study</h3><div>Evaluation of the diagnostic value of the basophil activation test (BAT) by flow cytometry in allergy to neuromuscular blocking agents (NMBA).</div></div><div><h3>Patients and methods</h3><div>One hundred and twenty-one patients older than 18 having experienced a grade II to IV peranesthetic shock were included in nine French hospitals. The final conclusion of the allegro-anesthesiologist was based on clinical and biological data and on skin tests, representing the “gold standard” of muscle relaxant agent's allergy diagnosis. The most frequently used NMBAs were suxamethonium, rocuronium and atracurium. Skin tests were performed according to EAACI recommendations and BAT according to Bühmann's laboratory protocol. BAT results were expressed in percentage of basophils expressing CD63 (%CD63) and in an activation index (AI) calculated according to a specific algorithm.</div></div><div><h3>Results</h3><div>Out of the 100 cases included, the positive (PPV) and negative (NPV) predictive values for ST were respectively 100% and 75%. For BAT, out of 64 cases, the PPV and NPV were respectively 100% and 41% (%CD63) and 100% and 51% (AI). The khi<sup>2</sup> test calculated between ST and BAT was statistically significant (<em>P</em> <!--><<!--> <!-->0.001) for suxamethonium and rocuronium. Using a threshold of 2 kUA/L (threshold corresponding to 100% specificity), the PPV and NPV of morphine specific IgEs were respectively 100% and 27%. Cross-reactions observed by TC and TAB for benzylisoquinolinium and aminosteroid compound groups were not significantly different.</div></div><div><h3>Conclusion</h3><div>The ST characteristics observed in this study are consistent with literature data with a lower NPV but a high PPV for BAT authorizing its use for diagnosis and selection of a negative NMBA with a view to subsequent intervention concerning a patient allergic to an NMBA. Its sensitivity is, however, lower than for TC but may be improved by the simultaneous use of an early activation marker as the membrane IgE.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 2","pages":"Article 104171"},"PeriodicalIF":0.3,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142528070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Gültuna , D.G.U. Erkaya , Y.S. Demirel , O. Aydın
{"title":"Characteristics of Fungal Monosensitization in Turkey","authors":"S. Gültuna , D.G.U. Erkaya , Y.S. Demirel , O. Aydın","doi":"10.1016/j.reval.2024.104162","DOIUrl":"10.1016/j.reval.2024.104162","url":null,"abstract":"<div><h3>Study Objective</h3><div>Fungi are recognized as allergenic sources and may play a role in the development, persistency, and severity of allergic diseases. Alternaria, Cladosporium, Penicillium, and Aspergillus, which belong to the Phylum Ascomycota, are well-characterized four genera among fungi species. To our knowledge, there is not enough data about monosensitization to fungi. We aimed to investigate the characteristics of monosensitized patients to fungal allergens.</div></div><div><h3>Patients-Methods</h3><div>Sixty-seven adult patients, who had a positive skin prick test reaction with fungal allergen out of a total of 4200 SPT results performed between January 2015 and June 2022 in two tertiary centers were included in the study. The clinical data of the patients were obtained retrospectively from the hospital medical records.</div></div><div><h3>Results</h3><div>Fifty-six (83.6%) patients were sensitized to one type of fungal allergen (Female/Male: 38/18) and eleven (16.4%) (Female/Male: 9/2) were sensitized to two types of fungi. Aspergillus was the most prevalent fungal allergen, followed by Cladosporium and Alternaria. Allergic rhinitis was the most common allergic disease.</div></div><div><h3>Conclusion</h3><div>Monosensitization to fungal allergens is rare. Monosensitization to at least one fungal allergen may lead to significant allergic diseases by potentially impacting the immune system.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"64 6","pages":"Article 104162"},"PeriodicalIF":0.3,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142527425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Allergie aux fruits à coque chez l’enfant : quelle prise en charge en pratique","authors":"F. Amat , E. Michaud","doi":"10.1016/j.reval.2024.104167","DOIUrl":"10.1016/j.reval.2024.104167","url":null,"abstract":"<div><div>Tree nuts are plant allergens frequently involved in allergic reactions to food in children. Among them, cashew, walnut, hazelnut, pistachio and almond are the most implicated, with sometimes anaphylactic reactions. The diagnosis of an allergy to nuts is simple and is based on history, skin tests, and biological assessment (specific IgE, molecular allergology). Cross-reactivity should be searched, between nuts but also with peanuts and sesame. It should be possible not to perform an oral food challenge in all cases to explore these potential cross-reactivities. Oral immunotherapy protocols, especially for hazelnuts, cashews, pistachio and walnuts are being developed.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 1","pages":"Article 104167"},"PeriodicalIF":0.3,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Yağmur , Ö. Kangalli Boyacioğlu , S. Asilsoy , D. Baysal Bakir , G. Kabadayi , D. Tezcan , Ö. Atay , N. Uzuner
{"title":"Investigation of the safety of measles–mumps–rubella vaccine in children with food allergies","authors":"H. Yağmur , Ö. Kangalli Boyacioğlu , S. Asilsoy , D. Baysal Bakir , G. Kabadayi , D. Tezcan , Ö. Atay , N. Uzuner","doi":"10.1016/j.reval.2024.104166","DOIUrl":"10.1016/j.reval.2024.104166","url":null,"abstract":"<div><h3>Study objective</h3><div>This study investigated the reaction frequency to the measles, mumps, rubella (MMR) vaccine and symptoms during this process in patients with egg allergy (EA) and/or cow's milk allergy (CMA).</div></div><div><h3>Patients and methods</h3><div>Patients diagnosed with CMA and/or EA were studied and followed up at the Department of Pediatric Allergy and Immunology, Dokuz Eylul University Faculty of Medicine, between December 2021 and December 2022. These patients were vaccinated with MMR vaccine (MMR vaccine from the Serum Institute of India Pvt. Ltd.). Demographic data, clinical findings, laboratory tests, and reactions following vaccination were reviewed.</div></div><div><h3>Results</h3><div>Overall, 62 patients with median age of 12<!--> <!-->months, including 46.8% males, were investigated; 56.5%, 40.3%, and 3.2% were followed up for atopic dermatitis, urticaria, and anaphylaxis, respectively. Moreover, 44% had EA, 21% had CMA, and 35% had CMA and EA (CM&EA). Among the CMA and CM&EA groups, allergen-specific immunoglobulin E (Sp IgE) for milk and total IgE levels were significantly different (<em>P</em> <!--><<!--> <!-->0.001). Significant differences were observed in Sp IgE levels and skin prick test (SPT) results for milk among the EA and CM&EA groups (<em>P</em> <!--><<!--> <!-->0.017). Anaphylactic reactions occurred in five patients following MMR vaccination. All these patients had CMA; no mortalities were reported.</div></div><div><h3>Conclusion</h3><div>Patients with food allergies should be evaluated before MMR vaccination. No reactions were observed in the group allergic to eggs. All patients who experienced reactions had CMA. This suggests that milk allergy is a significant risk factor for adverse reactions compared to EA.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 2","pages":"Article 104166"},"PeriodicalIF":0.3,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142442551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Bradatan , A.-K. Correard , D. Caimmi , A. Nemni , P. Biermé , C. Favre-Metz , D. Sabouraud , F. Morel Codreanu , E. Michaud , F. Villard-Truc , C. Braun
{"title":"Mise au point sur l’immunothérapie multi-aliment","authors":"E. Bradatan , A.-K. Correard , D. Caimmi , A. Nemni , P. Biermé , C. Favre-Metz , D. Sabouraud , F. Morel Codreanu , E. Michaud , F. Villard-Truc , C. Braun","doi":"10.1016/j.reval.2024.104163","DOIUrl":"10.1016/j.reval.2024.104163","url":null,"abstract":"<div><div>Multi-food oral immunotherapy (OIT) represents a potential avenue for the simultaneous management of multiple food allergies. It encompasses the ingestion of a range of allergens on a daily basis, with doses increasing progressively until a maintenance dose is reached. Multi-food OIT must follow a patient-centered approach. As with single-food OIT, multi-food OIT is responsible for mainly mild to moderate allergic reactions, which can be readily managed or prevented by conventional anti-allergy medication. However, the available literature suggests that multi-food OIT is as well tolerated as single-food OIT. The need for a technical platform and expertise continues to impede the accessibility of multi-food OIT. Low-dose OIT may be a solution to reduce allergic side effects and facilitating access to office-based multi-food OIT.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 1","pages":"Article 104163"},"PeriodicalIF":0.3,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Fikri , L. Bendaoud , M. Aboudourib , O. Hocar , S. Amal
{"title":"Acute localized exanthematous pustulosis caused by topical plant","authors":"C. Fikri , L. Bendaoud , M. Aboudourib , O. Hocar , S. Amal","doi":"10.1016/j.reval.2024.104147","DOIUrl":"10.1016/j.reval.2024.104147","url":null,"abstract":"<div><div>A 42-year-old woman presented with an acute eruption of multiple non-follicular pustules on an erythematous base, localized on the leg and hip, with mild pruritus. No mucosal or nail involvement. It appeared a few hours after the application of the medicinal plant “<em>Copparis</em><em>s</em><em>pinosa</em>” for sciatica in the leg and disappeared after withdrawing the plant. The diagnosis of ALEP was made according to recently proposed diagnostic criteria for acute localized exanthematous pustulosis (ALEP). ALEP is a rare skin reaction described as multiple non-follicular and sterile pustules developing on an erythematous background. The pathogenesis of ALEP is largely unknown. It is drug-induced in 84%, mainly by antibiotics, and non-drug-induced in 16%, mainly by herbal medicines. Herein, we report the first case of PEAL in Morocco caused by a herbal medicine, <em>Copparis</em><em>s</em><em>pinosa</em>.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 2","pages":"Article 104147"},"PeriodicalIF":0.3,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142442553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}