Revue Francaise d Allergologie最新文献

{"title":"Measles–mumps–rubella vaccine in children with food allergies","authors":"H. Yağmur , Ö. Atay , S. Asilsoy , N. Uzuner","doi":"10.1016/j.reval.2025.104617","DOIUrl":"10.1016/j.reval.2025.104617","url":null,"abstract":"","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 6","pages":"Article 104617"},"PeriodicalIF":0.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measles–Mumps–Rubella vaccine and cow's milk allergy","authors":"Ö. Özdemir","doi":"10.1016/j.reval.2025.104616","DOIUrl":"10.1016/j.reval.2025.104616","url":null,"abstract":"","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 6","pages":"Article 104616"},"PeriodicalIF":0.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eculizumab-Induced Stevens-Johnson Syndrome: The first pediatric case report in the literature","authors":"Ş.İ. Kökcü Karadağ ,&nbsp;D. Tekcan ,&nbsp;H. Nalçacıoğlu ,&nbsp;Ö. Aydoğ ,&nbsp;F. Öztürk","doi":"10.1016/j.reval.2025.104602","DOIUrl":"10.1016/j.reval.2025.104602","url":null,"abstract":"<div><div>Stevens-Johnson Syndrome is a severe mucocutaneous disease that frequently arises in response to medications and is rarely observed. To our knowledge, we report the first pediatric case of SJS induced by Eculizumab, documenting the potential risks associated with this treatment in children and making a significant contribution to the medical literature. A three-year old male patient diagnosed with atypical hemolytic uremic syndrome and treated with Eculizumab exhibited classical symptoms of SJS shortly after receiving his fourth dose. These symptoms included severe oral and labial ulcers, conjunctival hyperemia, and extensive erythematous macular rashes. Initial laboratory tests revealed an abnormal white blood cell count and elevated inflammatory markers, with a subsequent skin biopsy confirming SJS. Immediate initiation of intravenous steroid therapy resulted in substantial improvement in the patient. This report underscores the critical importance of early recognition and management of SJS, particularly in pediatric patients receiving monoclonal antibody therapy. The key lessons highlight the need for healthcare providers to remain vigilant about this rare but potentially fatal adverse effect, and to promptly discontinue treatment and intervene effectively to improve patient outcomes.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 6","pages":"Article 104602"},"PeriodicalIF":0.3,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145157538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early-onset serum sickness-like reaction: Role of drug provocation tests in diagnosis","authors":"B.C. Duran,&nbsp;E. Bahadir,&nbsp;S. Demirsöz,&nbsp;C. Aytekin,&nbsp;S. Özmen","doi":"10.1016/j.reval.2025.104603","DOIUrl":"10.1016/j.reval.2025.104603","url":null,"abstract":"<div><div>Serum sickness-like reaction (SSLR) is a rare, non-IgE-mediated hypersensitivity reaction typically occurring in early childhood, characterized by nonspecific symptoms such as rash, fever, and joint involvement. Although symptoms generally emerge 5–21 days after drug exposure, earlier onset may occur in sensitized individuals upon repeated exposure to the same agent. We report the case of a 5-year old boy who developed fever, erythema, and extremity pain within 12<!--> <!-->hours of a drug provocation test (DPT) with amoxicillin-clavulanic acid (ACA). A second DPT performed one month later triggered similar symptoms within 3<!--> <!-->hours, confirming the diagnosis of SSLR. Laboratory findings supported systemic inflammation, and the symptoms resolved with corticosteroid treatment. This case highlights the variability in SSLR symptom onset and emphasizes the potential utility of DPT in selected cases to confirm the diagnosis and avoid unnecessary drug elimination. It also draws attention to the need for careful patient selection and standardized protocols when performing DPT in suspected SSLR.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 6","pages":"Article 104603"},"PeriodicalIF":0.3,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145157543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"L’allergie à l’arachide. État des lieux et perspectives, par le GT2A. Partie 1 : épidémiologie et fardeau de l’allergie à l’arachide","authors":"G. Pouessel ,&nbsp;A. Deschildre ,&nbsp;F. Amat ,&nbsp;M. Morisset ,&nbsp;V. Jubin ,&nbsp;pour le Groupe de travail allergie alimentaire de la Société française d’allergologie","doi":"10.1016/j.reval.2025.104567","DOIUrl":"10.1016/j.reval.2025.104567","url":null,"abstract":"<div><div>This article is a non-systematic review on the epidemiology and burden of peanut allergy. Peanut allergy is one of the most common IgE-mediated food allergies in children, with an estimated prevalence in France of 0.9% at the age of 5.5 years based on questionnaires from the ELFE cohort. Peanut allergy begins in 90% of cases before the age of 3 years and spontaneously regresses in only 20 to 25% of cases before adulthood. Peanut allergy is associated with sensitization to one or more other legumes in two thirds of cases, and sometimes with a cross-allergy. Patients with peanut allergy most often have associated atopic comorbidities, particularly asthma. Peanut is one of the most common allergens involved in severe and even fatal food anaphylaxis and is associated with a high risk of allergy recurrence. Peanut allergy leads to impaired quality of life and has a significant psychosocial impact. Peanut-allergic patients probably have a different phenotype than patients with other food allergies. Multidisciplinary care and a personalized treatment strategy should be considered in these patients.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 5","pages":"Article 104567"},"PeriodicalIF":0.3,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144852440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Les effets indésirables suite à l’injection de la fluorescéine pour la réalisation de l’angiographie rétinienne : rapport de 4 cas","authors":"N. Taouri,&nbsp;A. Amazouzi,&nbsp;N. Boutimzine,&nbsp;O. Cherkaoui","doi":"10.1016/j.reval.2025.104598","DOIUrl":"10.1016/j.reval.2025.104598","url":null,"abstract":"<div><div>Fluorescein retinal angiography is a very well tolerated test; however adverse reactions of various severity have been reported, ranging from simple nausea to anaphylactic shock. Nausea, followed by vomiting are the most common anaphylactic incident after fluorescein injection. Premedication is sometimes indicated for patients at risk. Some authors propose desensitization protocols before carrying out an examination, while others propose as an alternative a retinal angiography with oral fluorescein, and sometimes the use of OCT (optical coherence tomography), or OCT-A (optical coherence tomography angiography). Finally, for more safety, it is important to equip the examination room with the necessary tools to manage this type of reactions. We report a retrospective study of 4 cases of adverse reaction following the injection of fluorescein for retinal angiography.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 5","pages":"Article 104598"},"PeriodicalIF":0.3,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144810500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rectorragies révélatrices d’une allergie alimentaire après une transplantation hépatique : à propos d’un cas","authors":"M. Sabib,&nbsp;T. Meskini,&nbsp;S. Ettair","doi":"10.1016/j.reval.2025.104600","DOIUrl":"10.1016/j.reval.2025.104600","url":null,"abstract":"<div><div>Les allergies alimentaires et hypersensibilités médicamenteuses sont des complications de plus en plus reconnues après transplantation hépatique pédiatrique, avec une prévalence pouvant atteindre 54,3 %. Les allergies alimentaires IgE-médiées se manifestent fréquemment par des signes cutanés et des symptômes gastro-intestinaux tels que douleurs abdominales et diarrhées, tandis que les rectorragies comme présentation initiale restent rares. Nous rapportons le cas original d’une fillette de 12 mois ayant bénéficié d’une transplantation hépatique à l’âge de 9 mois. Elle présentait une atrésie des voies biliaires, initialement traitée par dérivation bilio-digestive sans succès, ayant évolué vers une cirrhose hépatique compliquée d’insuffisance hépatocellulaire, motivant la greffe hépatique et la mise en place d’une immunosuppression par tacrolimus. Elle a présenté deux épisodes de rectorragies de grande abondance. Une évaluation allergologique a confirmé une allergie IgE-médiée à l’œuf et une proctocolite hémorragique associée à une hypersensibilité aux protéines du lait de vache. De plus, une hypersensibilité à l’aspirine a été confirmée par un test de provocation orale. La prise en charge a inclus un régime d’éviction de l’œuf de poule et du lait de vache ainsi qu’un protocole de désensibilisation à l’aspirine, entraînant une amélioration clinique juste après éviction des allergènes. La survenue de ces rectorragies pourrait s’expliquer par des perturbations immunitaires induites par la transplantation hépatique, notamment sous tacrolimus. Cet immunosuppresseur favorise une réponse Th2 avec production accrue d’IgE. Associé aux antibiotiques, il altère le microbiote intestinal et augmente la perméabilité digestive, facilitant la sensibilisation aux allergènes. Ce cas souligne l’importance d’un dépistage allergologique pré-greffe et d’un suivi étroit après transplantation. Une vigilance particulière doit être accordée aux manifestations cliniques atypiques, telles que les rectorragies, afin de ne pas méconnaître une cause allergique et d’optimiser la prise en charge.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 6","pages":"Article 104600"},"PeriodicalIF":0.3,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144809731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Syndrome d’entérocolite médicamenteuse induite par la ropivacaïne injectée par voie péri-nerveuse : premier cas rapporté","authors":"J. Herry ,&nbsp;C. Chassery ,&nbsp;M. Virtos ,&nbsp;D. Sabouraud ,&nbsp;P. Beaumont ,&nbsp;C. Ponvert","doi":"10.1016/j.reval.2025.104586","DOIUrl":"10.1016/j.reval.2025.104586","url":null,"abstract":"<div><div>Rare cases of drug-induced enterocolitis syndrome have been reported with drugs administered by the oral (amoxicillin, pantoprazole) and intrarectal (paracetamol) routes. No cases have been described by injectable route. Diagnostic criteria, close to those of food protein-induced enterocolitis syndrome, have been proposed in 2019. We report the case of a 72-year-old patient scheduled for a total knee arthroplasty and recused on two occasions after rapid occurrence of drug-induced enterocolitis after peri-nervous injection of ropivacaine during a nerve block carried out before the surgery. Skin tests performed after the first reaction, according to EEACI/ENDA (European Academy of Allergy and Clinical Immunology) recommendations, were negative. The drug provocation test with ropivacaine was also negative. However, the symptoms recurred at the second anesthesia. A few cases of IgE-mediated hypersensitivity to local anesthetics have been reported, but, to our knowledge, this is the first case of drug-induced enterocolitis syndrome induced by an injectable drug, ropivacaine, recurring although skin tests and provocation test resulted negative.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 6","pages":"Article 104586"},"PeriodicalIF":0.3,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144809730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact de la prise en charge multidisciplinaire sur le contrôle et l’évolution de l’asthme difficile","authors":"M. Oulad Kouider ,&nbsp;A. Fissah ,&nbsp;H. Madi ,&nbsp;M.S. Aissani ,&nbsp;K. Bouchbouch ,&nbsp;K. Ouennoughi ,&nbsp;A. Bachir Cherif ,&nbsp;F. Zedam ,&nbsp;L. Zemmour ,&nbsp;S. Benzaoui ,&nbsp;Z. Boukara ,&nbsp;M. Kibboua ,&nbsp;S. Alihalassa","doi":"10.1016/j.reval.2025.104599","DOIUrl":"10.1016/j.reval.2025.104599","url":null,"abstract":"<div><h3>Introduction</h3><div>Although patients with severe asthma constitute only around 5% to 10% of asthmatic patients, they account for almost half of the costs related to this condition. This situation is related to the disease itself and its comorbidities.</div></div><div><h3>Methods</h3><div>This is a prospective observational study in the academic hospital of Blida in Algeria. Data were collected from May 2019 to November 2021. Only patients who met the criteria of severe asthma according to the definition GINA 2018. The included patients received a multidisciplinary approach along with personalized education.</div></div><div><h3>Results</h3><div>One hundred and fifty patients were included, and 65.3% of them were women. Among the patients, 93.3% had comorbidities, with chronic allergic rhinitis being the most common allergic comorbidity. Meanwhile, gastroesophageal reflux was the most prevalent non-allergic comorbidity (48.7%). After multidisciplinary care, only 27.3% of the participants continued to have severe asthma.</div></div><div><h3>Conclusion</h3><div>Patients with severe asthma require personalized education and the collaboration of different specialists.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 6","pages":"Article 104599"},"PeriodicalIF":0.3,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144809729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing allergenicity of urban parks: Ordu City","authors":"S. Türkiş ,&nbsp;F.E. Günaydin","doi":"10.1016/j.reval.2025.104582","DOIUrl":"10.1016/j.reval.2025.104582","url":null,"abstract":"<div><div>Higher average temperatures due to climate change tend to change the spatial and temporal distribution of pollens. The study area was conducted in the Urban Park areas of Ordu Province, where urban people spend the most time. In the last decade, various allergenicity indices such as Specific Allergenicity Index (SAI) and Urban Green Zone Allergenicity Index (IUGZA) have been proposed to control hypoallergenicity in urban areas. The study aimed to warn allergic individuals about the risk posed by pollens and evaluate the allergenicity of existing urban vegetation. Specific Allergenicity Index (SAI) and Urban Green Zone Allergenicity Indexes (IUGZA<!--> <!-->=<!--> <!-->0.208) of 25 plant species spread in urban park areas were calculated. To determine these indices, life cycle, overlap-abundance values, height, pollination time, pollination process, allergenicity potential, and cross-reactivity values of the species were determined. Among the species, the species with the highest allergenic effect, i.e. both abundance and allergenic potential, is <em>Corylus avellana</em> var <em>avellana</em>. In terms of allergenic potential value (VPA), it is seen that <em>C.</em> <em>avellana</em> var. <em>avellana</em>, <em>Alnus glutinosa</em>, <em>Cupressus sempervirens</em>, <em>Olea europae</em>, <em>Salix</em> spp. and <em>Acer</em> spp. are the most effective species on the axes. The abundance of the species (0.802) was the factor that made the allergenic factors most effective. Determination of the urban allergenicity index of Ordu province to determine the ecological driving forces of the distribution of ecosystems is important in estimating the allergenicity index of urban green areas and in selecting the right species to minimize the allergenic in parks.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"65 5","pages":"Article 104582"},"PeriodicalIF":0.3,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144772429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}