American Journal of Case Reports最新文献_第9页

Morvan Fibrillary Chorea Associated with Monoclonal B Cell Lymphocytosis. 与单克隆 B 细胞淋巴细胞增多症相关的莫凡纤维性舞蹈症

IF 1

American Journal of Case Reports Pub Date : 2024-07-04 DOI: 10.12659/AJCR.943867

Daniel Park, Jeffrey Means, Andrew W Campion, Alan Kelton, Seema Nagpal, Haifaa Abdulhaq

{"title":"Morvan Fibrillary Chorea Associated with Monoclonal B Cell Lymphocytosis.","authors":"Daniel Park, Jeffrey Means, Andrew W Campion, Alan Kelton, Seema Nagpal, Haifaa Abdulhaq","doi":"10.12659/AJCR.943867","DOIUrl":"10.12659/AJCR.943867","url":null,"abstract":"BACKGROUND Morvan fibrillary chorea (Morvan syndrome) is a rare disorder marked by a collection of neurological symptoms such as myokymia, peripheral nerve excitability, neuromyotonia, autonomic instability, memory impairment, and delirium. Morvan syndrome is suspected to occur through antibodies directed against voltage gated potassium channels (VGKC), and has been linked with several autoimmune conditions and hematologic malignancies. We present a case of Morvan syndrome in association with monoclonal B cell lymphocytosis. Upon our literature review, we believe this to be the first documented case of Morvan syndrome associated with monoclonal B cell lymphocytosis. CASE REPORT The present case report describes a 75-year-old man with Morvan's syndrome. The patient had a diverse neurologic presentation with encephalopathy, progressive neuropathic pain, muscle fasciculations, myokymia, sensory deficits, and Bell's palsy. Ultimately, a paraneoplastic antibody panel revealed a positive titer of contactin-associated protein-like IgG (CASPR) and VGKC antibody. Flow cytometry showed a small population of abnormal lambda-restricted B cells. Given his symptoms, positive CASPR antibody, and flow cytometry findings, he was diagnosed with Morvan syndrome associated with monoclonal B cell lymphocytosis. He was treated with IV methylprednisolone and IVIG, with immediate improvement in neurologic symptoms. CONCLUSIONS Morvan syndrome presents with a spectrum of neurologic symptoms and is associated with autoantibodies against VGKC through anti-CASPR2 antibodies. Classically, Morvan syndrome presents as a paraneoplastic disease secondary to thymomas. Our case demonstrates that there is an association between B cell lymphoproliferative disorders and Morvan syndrome.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141535596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Triple-Negative Pleomorphic Lobular Carcinoma in a BRCA1 Mutation Carrier: A Case of Complete Pathological Response BRCA1 基因突变携带者的三阴性多形性小叶癌：一例完全病理反应病例

IF 1

American Journal of Case Reports Pub Date : 2024-07-04 DOI: 10.12659/ajcr.943882

Maheshika Jinadasa, Alex Humphreys, Eleanore Massey, Patricia Vergani, Makaela Jacob-Pearson, Katherine Smith, Sarah Vinnicombe, Thomas Papathomas

引用次数: 0

Unmasking Pott Disease: A Diagnostic Challenge Mimicking Metastatic Lung Cancer – A Case Report 揭开波特病的面纱：模仿转移性肺癌的诊断难题--病例报告

IF 1

American Journal of Case Reports Pub Date : 2024-07-03 DOI: 10.12659/ajcr.943578

A. Romaszko-Wojtowicz, Ewa Malinowska, Anna Doboszyńska

引用次数: 0

Repeated Minimally Invasive Pancreatectomy for Intraductal Papillary Mucinous Neoplasm in the Remnant Pancreas: A Case Report 残余胰腺导管内乳头状黏液瘤的重复微创胰切除术：病例报告

IF 1

American Journal of Case Reports Pub Date : 2024-07-03 DOI: 10.12659/ajcr.944405

B. Askeyev, T. Adachi, H. Imamura, M. Yamashita, Kantoku Nagakawa, T. Hara, H. Matsushima, A. Soyama, Zhassulan Baimakhanov, Bolatbek Baimakhanov, S. Eguchi

引用次数: 0

Direct Visualization of a Cesarean Scar Ectopic Pregnancy After Medical Management. 剖腹产疤痕宫外孕医疗处理后的直接可视化。

IF 1

American Journal of Case Reports Pub Date : 2024-07-03 DOI: 10.12659/AJCR.944396

Amy Hua, Catherine Igel, Dmitry Fridman, Ivan Ngai

{"title":"Direct Visualization of a Cesarean Scar Ectopic Pregnancy After Medical Management.","authors":"Amy Hua, Catherine Igel, Dmitry Fridman, Ivan Ngai","doi":"10.12659/AJCR.944396","DOIUrl":"10.12659/AJCR.944396","url":null,"abstract":"BACKGROUND Cesarean scar ectopic pregnancy is a rare type of ectopic pregnancy that can result in severe maternal morbidity and mortality. Medical, surgical, and minimally invasive therapies alone or in combination have been described in the literature, but the optimal treatment modality of cesarean scar ectopic pregnancies is unknown. Limited information exists on the course of cesarean scar ectopic pregnancy following treatment with cytotoxic agents. CASE REPORT We present a case of a woman with a history of multiple cesarean births that was provided with medical abortion for an unintended pregnancy. However, upon follow-up, the patient was found to have a cesarean scar ectopic pregnancy. Following the diagnosis, she was treated by multi-dose systemic methotrexate-leucovorin and with ultrasound-guided intra-gestational sac injection of potassium chloride. After resolution of beta human gonadotropin levels, ultrasound follow-up revealed persistence of residual tissue in the cesarean scar. The patient elected for resection of the residual tissue with operative hysteroscopy. We report a novel hysteroscopic finding after medical treatment of a cesarean scar ectopic pregnancy with intra-gestational sac injection of potassium chloride. CONCLUSIONS Direct visualization of the intra-abdominal cavity and intra-uterine cavity showed that combined medical management with systemic methotrexate and local potassium chloride injection is an effective treatment modality for live cesarean scar ectopic pregnancies, with minimal anatomical harm. Hysteroscopic resection offers a safe and effective approach for removal of persistence of residual tissue.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-Term Success in Dental Implant Revisions: A 31-Year Case Study of Alveolar Atrophy Management in an Elderly Woman 种植牙翻修的长期成功：一名老年妇女牙槽萎缩管理的 31 年案例研究

IF 1

American Journal of Case Reports Pub Date : 2024-07-02 DOI: 10.12659/ajcr.943341

Carlo Piccoli, Gabriele Soliani, Paolo Piccoli, Aldo Zupi

引用次数: 0

Long-Term Remission in T315I+ Relapsed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with Blinatumomab and Allogeneic Stem Cell Transplantation: Two Case Studies T315I+复发性费城染色体阳性急性淋巴细胞白血病患者使用Blinatumomab和异基因干细胞移植后的长期缓解：两个病例研究

IF 1

American Journal of Case Reports Pub Date : 2024-07-02 DOI: 10.12659/ajcr.944956

Ziyang Huang, Yu Zhang, Jingjing Chen, Yifen Shi, Peng Chen, Songfu Jiang, Honglan Qian

引用次数: 0

A 68-Year-Old Man with Depression and Acute Renal Failure Due to Rhabdomyolysis Associated with Alcohol Intoxication While Taking Low-Dose Escitalopram: A Case Report. 一名 68 岁男性在服用小剂量艾司西酞普兰期间，因酒精中毒引起横纹肌溶解而导致抑郁和急性肾衰竭：病例报告。

IF 1

American Journal of Case Reports Pub Date : 2024-07-02 DOI: 10.12659/AJCR.943422

Daniela Cana Ruiu, Daniela Teodora Maria, Romeo Popa, Sabrina Moraru, Elena Georgia Micu, Cristina Vaduva, Naomi Fota, Dragos George V Popa, Anca Cojocaru, Daniela Calina

{"title":"A 68-Year-Old Man with Depression and Acute Renal Failure Due to Rhabdomyolysis Associated with Alcohol Intoxication While Taking Low-Dose Escitalopram: A Case Report.","authors":"Daniela Cana Ruiu, Daniela Teodora Maria, Romeo Popa, Sabrina Moraru, Elena Georgia Micu, Cristina Vaduva, Naomi Fota, Dragos George V Popa, Anca Cojocaru, Daniela Calina","doi":"10.12659/AJCR.943422","DOIUrl":"10.12659/AJCR.943422","url":null,"abstract":"BACKGROUND Rhabdomyolysis, an uncommon but recognized adverse effect of selective serotonin reuptake inhibitor (SSRI) antidepressants, can precipitate acute renal injury (AKI), especially when combined with risk factors such as alcohol consumption. This report describes a 68-year-old man with acute renal failure due to rhabdomyolysis associated with alcohol intoxication while taking low-dose escitalopram, an SSRI antidepressant. CASE REPORT The patient, with a history of bipolar affective disorder managed with escitalopram, presented with symptoms of general malaise, diarrhea, myalgias, and transient loss of consciousness following substantial ethanol consumption. Laboratory tests indicated severe rhabdomyolysis with a creatine kinase level of 37 672 U/L and myoglobin level >5710 ng/ml, leading to an AKI diagnosis. The discontinuation of escitalopram, along with hydration and renal replacement therapy, facilitated renal recovery. However, the reintroduction of escitalopram resulted in the recurrence of rhabdomyolysis, suggesting a probable causal link, confirmed using the Naranjo Adverse Drug Reaction Probability Scale. CONCLUSIONS This report highlights the importance of identifying the medication history in patients presenting with acute renal failure and rhabdomyolysis and the association with SSRIs, which can be exacerbated by alcohol. This case underscores the importance of vigilant medication history assessment in patients presenting with AKI and rhabdomyolysis, particularly concerning the use of SSRIs like escitalopram, which can pose heightened risks in the context of alcohol use. It highlights the need for clinical caution in managing patients on long-term SSRI therapy, especially when reintroducing such medications after an episode of rhabdomyolysis.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effective Radiation Therapy for Isolated Apical Pulmonary Amyloidoma: A Case Report and Treatment Insight 孤立性肺尖部淀粉样变性的有效放射治疗：病例报告与治疗启示

IF 1

American Journal of Case Reports Pub Date : 2024-07-02 DOI: 10.12659/ajcr.944582

Wissam Harmouch, Angela Waguespack, James McHenry, Anita Mercado

引用次数: 0

Ileo-Ileal Intussusception Secondary to Neuroendocrine Tumor in Adult Patient 成人患者继发于神经内分泌肿瘤的回肠-回肠套叠

IF 1

American Journal of Case Reports Pub Date : 2024-07-02 DOI: 10.12659/ajcr.944872

Sahil M Patel, Varshini Venkatesan, Ashley A. Barras, Lauren L. Pacheco

引用次数: 0