American Journal of Case Reports最新文献_第8页

Severe Disseminated Adenovirus Infection After Haploidentical Hematopoietic Stem Cell Transplantation: A Case Report. 单倍体造血干细胞移植后严重播散性腺病毒感染1例。

IF 0.7

American Journal of Case Reports Pub Date : 2025-09-04 DOI: 10.12659/AJCR.947215

Daniel Taehyun Yang, Nazmul Hasan, Dinora B Chinchilla, Emily Blodget

{"title":"Severe Disseminated Adenovirus Infection After Haploidentical Hematopoietic Stem Cell Transplantation: A Case Report.","authors":"Daniel Taehyun Yang, Nazmul Hasan, Dinora B Chinchilla, Emily Blodget","doi":"10.12659/AJCR.947215","DOIUrl":"10.12659/AJCR.947215","url":null,"abstract":"BACKGROUND Adenoviruses are double-stranded DNA viruses capable of causing a spectrum of diseases from mild respiratory infections to severe systemic illnesses. Disseminated adenovirus is evidenced by gastrointestinal, pulmonary, genitourinary, neurologic and even cardiac involvement. In immunocompromised individuals, adenovirus infections can become severe and are often associated with significant morbidity and mortality. CASE REPORT A 52-year-old man with a history of large granular lymphocytic (LGL) leukemia underwent haploidentical hematopoietic stem cell transplantation (HSCT). His course was complicated by the diagnosis of hemorrhagic cystitis with findings of adenovirus. His condition rapidly declined, necessitating Intensive Care Unit (ICU) admission. Comprehensive workup identified adenovirus in the serum and cerebrospinal fluid (CSF), bronchoalveolar lavage fluid, and positive stool adenovirus. Echocardiographic evaluation revealed a moderate pericardial effusion requiring pericardiocentesis. Unfortunately, adenovirus testing of the aspirate could not be performed. Given the diagnosis of disseminated adenovirus infection, treatment with cidofovir and probenecid was initiated, but despite these interventions, the patient's status continued to deteriorate complicated by multiorgan failure and refractory shock. CONCLUSIONS This case underscores the complexity of diagnosing disseminated adenovirus, particularly given the potential for multiorgan system involvement. Early recognition is essential, such as viral polymerase chain reaction (PCR), playing a critical role in the identification and monitoring of infection. The case further emphasizes the pressing need for continued research into novel antiviral therapies and preventive measures to mitigate the risk of adenovirus in this vulnerable population.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":"26 ","pages":"e947215"},"PeriodicalIF":0.7,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12418897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laparoscopic Resection of a Rare Retroperitoneal Dermoid Cyst in a 78-Year-Old Woman: A Case Report. 腹腔镜下切除78岁女性罕见腹膜后皮样囊肿1例。

IF 0.7

American Journal of Case Reports Pub Date : 2025-09-03 DOI: 10.12659/AJCR.947666

Yuanchen Lu, Quan Li, Qijie Zhang, Xianhua Shao, Hua Shen, Junpeng Deng, Hongliang Que, Tengyue Zeng, Jinqi Hua, Yichen Qian, Jianjun Xie

{"title":"Laparoscopic Resection of a Rare Retroperitoneal Dermoid Cyst in a 78-Year-Old Woman: A Case Report.","authors":"Yuanchen Lu, Quan Li, Qijie Zhang, Xianhua Shao, Hua Shen, Junpeng Deng, Hongliang Que, Tengyue Zeng, Jinqi Hua, Yichen Qian, Jianjun Xie","doi":"10.12659/AJCR.947666","DOIUrl":"10.12659/AJCR.947666","url":null,"abstract":"BACKGROUND Primary retroperitoneal tumors (PRTs) are uncommon, with retroperitoneal dermoid cysts being particularly rare. The cystic cavity of mature cystic teratomas (dermoid cysts) is lined with squamous epithelium and primarily filled with sebaceous material. These lesions often lack specific symptoms, leading to delayed diagnosis. Imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI) are crucial for identifying these lesions, but definitive diagnosis relies on pathological examination. Surgical resection is the primary treatment, particularly for symptomatic or enlarging lesions. This report describes a case of a 78-year-old woman presenting with hydronephrosis secondary to a solitary retroperitoneal mature cystic teratoma (dermoid cyst) removed by laparoscopic resection. CASE REPORT A 78-year-old woman presented with left renal occupancy and severe hydronephrosis detected during routine health screening. Imaging studies revealed a retroperitoneal cystic mass compressing the upper urinary tract. She underwent laparoscopic resection of the mass and nephrectomy. Histopathological examination confirmed the diagnosis of an isolated retroperitoneal mature cystic teratoma. Postoperatively, she recovered well and remained asymptomatic during follow-up. CONCLUSIONS Retroperitoneal dermoid cysts are rare and pose diagnostic challenges due to their nonspecific clinical and imaging features. Early diagnosis and surgical intervention are critical to preventing complications and preserving organ function. This case report discusses the importance of preoperative evaluation and early treatment, highlighting the urgency of optimizing and standardizing the diagnosis and management of such diseases.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":"26 ","pages":"e947666"},"PeriodicalIF":0.7,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Portomesenteric Vein Thrombosis Following Sleeve Gastrectomy: A Case Report and Literature Review. 套筒胃切除术后肠系膜静脉血栓1例并文献复习。

IF 0.7

American Journal of Case Reports Pub Date : 2025-09-03 DOI: 10.12659/AJCR.947151

Jóse Sergio Verboonen Sotelo, Jaime Ponce de León Palomares, Jeffry Romero Manzano, Hector Joaquin Pérez Corzo, Jesus Antonio Villalobos López, Gustavo Adolfo Linden Pérez-Gavilán, Guillermo Vega Tostado, Gabriela Verboonen Partida

{"title":"Portomesenteric Vein Thrombosis Following Sleeve Gastrectomy: A Case Report and Literature Review.","authors":"Jóse Sergio Verboonen Sotelo, Jaime Ponce de León Palomares, Jeffry Romero Manzano, Hector Joaquin Pérez Corzo, Jesus Antonio Villalobos López, Gustavo Adolfo Linden Pérez-Gavilán, Guillermo Vega Tostado, Gabriela Verboonen Partida","doi":"10.12659/AJCR.947151","DOIUrl":"10.12659/AJCR.947151","url":null,"abstract":"BACKGROUND The prevalence of obesity has more than doubled since 1980. Consequently, bariatric surgery rates have risen significantly, increasing the need to address its complications. Portomesenteric venous thrombosis is a rare but potentially life-threatening complication, accounting for 5% to 15% of all mesenteric ischemic events. This case highlights the importance of considering portomesenteric vein thrombosis as a potential complication in bariatric surgery, especially in patients at high risk. CASE REPORT A 28-year-old woman with grade II obesity underwent elective laparoscopic sleeve gastrectomy. On postoperative day 7, she presented with diarrhea and vomiting (over 10 episodes in a weekend), dry mucosa, vague abdominal pain radiating to the lumbar region, and intolerance to oral intake. After 48 h with no improvement, a contrast-enhanced abdominal and pelvic computed tomography scan (January 7, 2024) revealed intravascular defects in the portal vein, superior mesenteric vein, and splenic vein, suggesting thrombosis. CONCLUSIONS The etiology of portomesenteric vein thrombosis following bariatric surgery is likely multifactorial. While the relationship between venous thromboembolism and obesity is well established, debates persist regarding the optimal duration of medical therapy after discharge, despite the existing preventive measures in the literature. Some 95% of surgeons administer anticoagulants for at least 10 to 14 days postoperatively, while 50% extend prophylaxis for up to 30 days, depending on individual risk factors. While gastric sleeve surgery offers substantial benefits for patients with obesity, the rising incidence of portal mesenteric thrombosis underscores the importance of proactive prevention and early detection strategies.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":"26 ","pages":"e947151"},"PeriodicalIF":0.7,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12416343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ex-Utero Intrapartum Treatment for a Fetal Cervical Teratoma with Mediastinal Extension: A Case Report. 胎儿宫颈畸胎瘤纵膈延伸的子宫外-产内治疗1例。

IF 0.7

American Journal of Case Reports Pub Date : 2025-09-02 DOI: 10.12659/AJCR.949318

Madison Crew, Caitlin R Eason, Courtney Breckenfelder, James Jaggers, Sarah A Gitomer, Regina M Reynolds, Michael V Zaretsky, S Christopher Derderian

{"title":"Ex-Utero Intrapartum Treatment for a Fetal Cervical Teratoma with Mediastinal Extension: A Case Report.","authors":"Madison Crew, Caitlin R Eason, Courtney Breckenfelder, James Jaggers, Sarah A Gitomer, Regina M Reynolds, Michael V Zaretsky, S Christopher Derderian","doi":"10.12659/AJCR.949318","DOIUrl":"10.12659/AJCR.949318","url":null,"abstract":"BACKGROUND Ex-utero intrapartum treatment (EXIT)-to-airway is a complex perinatal procedure performed in the case of potential postnatal airway obstruction. It requires an experienced multidisciplinary team and meticulous surgical planning based on fetal imaging. This report describes the use of EXIT-to-airway for a large cervical teratoma with extension into the mediastinum. CASE REPORT At 35 weeks' gestation, a 29-year-old woman presented to our fetal care center with significant polyhydramnios. The fetus was subsequently diagnosed with a large cervical mass extending into the mediastinum. An EXIT-to-airway procedure was performed at 36 weeks' gestation. The neonate remained intubated while postnatal imaging was obtained. At day of life 3, resection of the teratoma was performed via a combined cervical and mediastinal approach. Pathology confirmed a mature teratoma. The neonate's hospital course was complicated by aspiration with feeding, requiring a gastrostomy tube, and she was discharged on day of life 40. CONCLUSIONS While cervical teratoma is a well-established indication for the EXIT procedure, this case is notable for its late third-trimester diagnosis and the rare extension of the mass into the mediastinum, which necessitated a dual surgical approach. It highlights the importance of maintaining a broad differential diagnosis in the setting of recurrent third-trimester polyhydramnios and demonstrates the critical role of multidisciplinary planning in optimizing outcomes when airway compromise is anticipated. This case contributes to the growing body of evidence supporting the expanded utility of EXIT-to-airway for complex cervicomediastinal masses.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":"26 ","pages":"e949318"},"PeriodicalIF":0.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413765/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-Surgical Resolution of Phytobezoar-Induced Bowel Obstruction Using Sodium Bicarbonate and Catheter: A Report of 2 Cases. 碳酸氢钠加导管非手术治疗植粪草引起的肠梗阻2例报告。

IF 0.7

American Journal of Case Reports Pub Date : 2025-09-02 DOI: 10.12659/AJCR.949831

Binglong Bai, Jingying Zhang, Hengqing Zhu, Zhiyu Li

{"title":"Non-Surgical Resolution of Phytobezoar-Induced Bowel Obstruction Using Sodium Bicarbonate and Catheter: A Report of 2 Cases.","authors":"Binglong Bai, Jingying Zhang, Hengqing Zhu, Zhiyu Li","doi":"10.12659/AJCR.949831","DOIUrl":"10.12659/AJCR.949831","url":null,"abstract":"BACKGROUND Phytobezoar-induced small bowel obstruction presents significant management challenges, particularly in patients who either decline surgery or have contraindications. These concretions, predominantly composed of persimmon tannins, account for 0.4-4.8% of intestinal obstructions in endemic regions. While surgical intervention remains standard for complete obstructions, non-surgical approaches are increasingly explored for high-risk patients. Current dissolution therapies, including the Coca-Cola protocol, often require large fluid volumes that can exacerbate the obstruction. This study evaluated the efficacy of a novel treatment using low-volume sodium bicarbonate irrigation combined with catheter decompression. CASE REPORT Two elderly men (aged 73 and 74 years) with persimmon-induced obstructions refractory to conservative treatment underwent endoscopic intestinal catheter placement. Targeted 5% sodium bicarbonate irrigation (100 mL bid) with intermittent catheter clamping was administered. Clinical progress was monitored through serial imaging and symptom assessment. Both cases achieved complete obstruction resolution without surgery. Case 1 demonstrated CT-confirmed bezoar reduction within 10 days, with spontaneous passage. Case 2 expelled a 3×7 cm bezoar after 5 days of therapy. No procedural complications or biochemical imbalances occurred. The protocol synergized bicarbonate's mucolytic action (alkaline dissolution of phytobezoar matrices) with mechanical catheter decompression. CONCLUSIONS This first-reported combination therapy successfully resolved large phytobezoars (4-7 cm) within 5-10 days, establishing a safe alternative for candidates who either decline surgery or have contraindications. The method's efficacy stems from: 1) minimized fluid volume requirements (200 mL/day vs 500-3000 mL in Coca-Cola protocols), 2) direct bezoar contact via catheter-directed delivery, and 3) dual mechanical-chemical action.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":"26 ","pages":"e949831"},"PeriodicalIF":0.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Staphylococcus-Induced Glomerulonephritis Following Burn Injury: A Case Report. 烧伤后葡萄球菌性肾小球肾炎1例报告。

IF 0.7

American Journal of Case Reports Pub Date : 2025-09-01 DOI: 10.12659/AJCR.948976

Tatsunori Nagamura, Hiroshi Kato, Kazue Tashiro, Tetsuro Kiyozumi

{"title":"Staphylococcus-Induced Glomerulonephritis Following Burn Injury: A Case Report.","authors":"Tatsunori Nagamura, Hiroshi Kato, Kazue Tashiro, Tetsuro Kiyozumi","doi":"10.12659/AJCR.948976","DOIUrl":"10.12659/AJCR.948976","url":null,"abstract":"BACKGROUND Infection-related glomerulonephritis occurs when immune complexes formed in response to bacterial infection injure the glomerular basement membrane. Here, we describe a rare case of Staphylococcus-induced glomerulonephritis following burn injury. CASE REPORT A 65-year-old woman was admitted to the Emergency Department after sustaining multiple burns from boiling water. She had second-degree burns covering 19% of her total body surface area and received conservative treatment. On day 4, she developed a burn wound infection caused by methicillin-susceptible Staphylococcus aureus and Pseudomonas aeruginosa. Antibiotic therapy was initiated; however, she developed a sudden and rapid deterioration in kidney function on day 15. Sepsis-associated acute kidney injury was initially suspected, and the fluid infusion rate was increased accordingly. However, her kidney function deteriorated further, and she subsequently developed generalized edema. After considering the staphylococcal wound infection, marked hematuria and proteinuria, and hypocomplementemia, the diagnosis was revised to Staphylococcus-induced glomerulonephritis secondary to the burn wound infection. Fluid restriction and intermittent hemodialysis were initiated on day 19 of hospitalization. Her clinical condition improved approximately 1 month later, and a kidney biopsy result on day 74 was consistent with the recovery phase of infection-related glomerulonephritis. The patient was discharged 94 days after admission. CONCLUSIONS Acute kidney injury secondary to a burn wound infection should be distinguished from infection-related glomerulonephritis and sepsis-associated acute kidney injury. Source control and fluid restriction are recommended when infection-related glomerulonephritis is suspected in older patients with staphylococcal wound infections, marked proteinuria or hematuria, and hypocomplementemia.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":"26 ","pages":"e948976"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ménétrier Disease: Rare Manifestations and Mechanistic Insights From 2 Adult Cases. 2例成人病例的罕见表现和发病机制。

IF 0.7

American Journal of Case Reports Pub Date : 2025-09-01 DOI: 10.12659/AJCR.949111

Jialin Wu, Yijun Chen, Jie Yin, Peng Li, Haiyi Hu

{"title":"Ménétrier Disease: Rare Manifestations and Mechanistic Insights From 2 Adult Cases.","authors":"Jialin Wu, Yijun Chen, Jie Yin, Peng Li, Haiyi Hu","doi":"10.12659/AJCR.949111","DOIUrl":"10.12659/AJCR.949111","url":null,"abstract":"BACKGROUND Menetrier disease is a rare gastric disorder characterized by hypertrophic hyperplastic changes in the stomach mucosa, hypoproteinemia, and symptoms like abdominal pain and diarrhea. It predominantly affects men aged 40-60 years and involves protein loss from the stomach. There have been few reports of cases complicated with severe anemia and secondary gastric outlet obstruction. The pathogenesis in adults remains unclear, although pediatric cases often are associated with cytomegalovirus (CMV) infection. CASE REPORT We present 2 adult cases. Case 1 was a 35-year-old man with a 2-month history of epigastric pain, vomiting, melena, and severe anemia. Lab tests revealed hypoproteinemia and low hemoglobin. Imaging and endoscopy showed gastric wall thickening, a gastric mass, and mucosal abnormalities. Histopathology confirmed Menetrier disease. Case 2 was a 44-year-old man with 6 years of epigastric fullness and belching. He had hypoproteinemia and multiple gastric nodules. Endoscopy revealed enlarged mucosal folds and polyps. Biopsies showed chronic inflammation and foveolar hyperplasia, consistent with Menetrier disease. CONCLUSIONS These cases highlight the diagnostic challenges of Menetrier disease, emphasizing the need for integrated clinical, endoscopic, and histopathological evaluation. Further studies are needed to explore the associations between Menetrier disease, Helicobacter pylori (H. pylori) infection, and gastric cancer.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":"26 ","pages":"e949111"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid-Onset Venous Thrombosis After Tibia Fracture: A Case Report. 胫骨骨折后快速发生静脉血栓1例。

IF 0.7

American Journal of Case Reports Pub Date : 2025-08-31 DOI: 10.12659/AJCR.948654

Caiquan Long, Zizhen Xie, Weili Luo, Haotian Wang

{"title":"Rapid-Onset Venous Thrombosis After Tibia Fracture: A Case Report.","authors":"Caiquan Long, Zizhen Xie, Weili Luo, Haotian Wang","doi":"10.12659/AJCR.948654","DOIUrl":"10.12659/AJCR.948654","url":null,"abstract":"BACKGROUND Conventional clinical understanding holds that venous thrombus formation typically occurs days after traumatic injury. However, our findings demonstrate that acute thrombosis can begin within 7.5 hours after fracture in knee trauma cases, challenging existing paradigms. CASE REPORT A 43-year-old man was admitted to the Emergency Department (ED) after an electric bicycle accident precipitated by acute-onset dizziness accompanied by visual disturbances. Initial radiographic evaluation confirmed a comminuted right proximal tibia fracture with concomitant multiple acute ischemic cerebral infarctions on neuroimaging. Compression ultrasonography performed in the ED showed no evidence of deep venous thrombosis in the lower extremities. However, markedly elevated D-dimer levels (9.39 mg/L; reference <0.5 mg/L) prompted high clinical suspicion for occult venous thromboembolism. Serial Doppler ultrasound surveillance revealed the rapid development of a free-floating thrombus in the right soleal vein within 7.5 hours after the fracture occurred. CONCLUSIONS This case report documents the exceptionally rapid development of venous thrombosis within 7.5 hours following a proximal tibia fracture, particularly in high-risk patients with comorbid conditions such as diabetes mellitus and ischemic stroke. These findings necessitate immediate reassessment of current thromboprophylaxis protocols in orthopedic trauma, emphasizing the critical importance of early and frequent vascular monitoring (including serial Doppler ultrasonography and D-dimer assessment) to detect hyperacute thrombus formation. Clinicians must maintain heightened awareness of this emergency thromboembolic risk while simultaneously managing hemorrhage concerns, as this case demonstrates that the traditional 24-hour prophylaxis window may be inadequate for certain high-risk trauma populations.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":"26 ","pages":"e948654"},"PeriodicalIF":0.7,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transient Renal Artery Stenosis in Renal Infarction: A Case Report. 肾梗死中一过性肾动脉狭窄1例报告。

IF 0.7

American Journal of Case Reports Pub Date : 2025-08-30 DOI: 10.12659/AJCR.949596

George K Annan, Walter Agyeman, Samuel B Acheampong, Abigail Mills-Annoh, Albert Asare Adu

{"title":"Transient Renal Artery Stenosis in Renal Infarction: A Case Report.","authors":"George K Annan, Walter Agyeman, Samuel B Acheampong, Abigail Mills-Annoh, Albert Asare Adu","doi":"10.12659/AJCR.949596","DOIUrl":"10.12659/AJCR.949596","url":null,"abstract":"BACKGROUND Renal infarction is a rare condition resulting from interruption of renal arterial blood flow. Its nonspecific presentation often mimics more common diagnoses such as nephrolithiasis, pyelonephritis, or musculoskeletal pain, contributing to delayed or missed diagnosis. Early identification is essential to prevent irreversible renal damage and optimize patient outcomes. Imaging plays a critical role in both the initial diagnosis and in determining the underlying etiology, which may include thromboembolism, in-situ thrombosis, vascular injury, or hypercoagulable states. CASE REPORT We describe a case of a 63-year-old woman with a history of coronary artery disease, diabetes mellitus, hormone replacement therapy, and a 42 pack-year smoking history, who presented with sudden-onset, severe left-flank pain. Initial laboratory results were nonspecific, with mild proteinuria and microscopic hematuria. Computed tomography (CT) angiography demonstrated severe stenosis of the superior left renal artery and extensive left renal infarction. A diagnosis of atherosclerotic renal infarction was made. She was treated with intravenous heparin, transitioned to dual antiplatelet therapy and high-intensity statin, and discharged with a 30-day cardiac event monitor. No arrhythmia was detected, and her thrombophilia workup was negative. Follow-up CT angiography 1 month later revealed complete resolution of the renal artery stenosis, with no residual narrowing or plaque. The transient nature of the vascular finding, along with the lack of structural atherosclerosis, prompted diagnostic reassessment, favoring an embolic mechanism possibly related to multiple modifiable prothrombotic clinical risk factors and unrecognized embolic sources. CONCLUSIONS This case illustrates the importance of follow-up imaging and clinical reassessment in differentiating embolic from atherosclerotic causes of renal infarction.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":"26 ","pages":"e949596"},"PeriodicalIF":0.7,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12406750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radial Periosteal Distraction as a Novel Intervention for Raynaud Syndrome with Gangrene: A Case Report. 桡骨骨膜撑开术治疗雷诺综合征伴坏疽1例。

IF 0.7

American Journal of Case Reports Pub Date : 2025-08-29 DOI: 10.12659/AJCR.948422

Xiaoyu Zheng, Yang Yang, Hongliang Jin, Yiguo Chen, Wei Wang

{"title":"Radial Periosteal Distraction as a Novel Intervention for Raynaud Syndrome with Gangrene: A Case Report.","authors":"Xiaoyu Zheng, Yang Yang, Hongliang Jin, Yiguo Chen, Wei Wang","doi":"10.12659/AJCR.948422","DOIUrl":"10.12659/AJCR.948422","url":null,"abstract":"BACKGROUND Raynaud syndrome, also known as Raynaud phenomenon, is characterized by vasospasm of small blood vessels supplying the digits and is usually reversible but can rarely result in severe and irreversible ischemia. Periosteal distraction osteogenesis is a technique that creates a space between the periosteum and the bone surface to stimulate the formation of new bone. This report describes a 67-year-old woman with a 10-year history of Raynaud syndrome presenting with ischemia and gangrene of the right index and middle fingers managed with radial periosteal distraction osteogenesis. CASE REPORT Ten years earlier, the patient received a diagnosis of Raynaud syndrome and had been taking nifedipine sustained-release tablets orally for symptom control ever since. Two weeks before presentation, she successfully recovered from septic shock through the rescue of the Intensive Care Unit. One week before presentation, the patient experienced an aggravation of pain in both fingers. Her distal ends of the right index and middle fingers became darker. After performing the relevant examinations, she received a diagnosis of Raynaud syndrome (bilateral) and gangrene of the right finger. Following the exclusion of surgical contraindications, radial periosteal distraction was performed. The periosteum was continuously distracted after the operation. During follow-up, the patient's gangrene gradually progressively healed, and the pain in both hands markedly diminished. CONCLUSIONS This report supports recent studies that have shown the potential for periosteal distraction osteogenesis in the management of cases of severe and irreversible Raynaud disease of the digits.","PeriodicalId":39064,"journal":{"name":"American Journal of Case Reports","volume":"26 ","pages":"e948422"},"PeriodicalIF":0.7,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12404003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0