Journal of Feline Medicine and Surgery Open Reports最新文献

{"title":"Reversible congestive heart failure associated with diabetes mellitus in two cats.","authors":"Jaechun Cho, Seung-Woo Cho, Yongsun Kim, Eun-Gee Lee, Mihyun Choi, Min-Suk Kim, Chul Park","doi":"10.1177/20551169261446703","DOIUrl":"10.1177/20551169261446703","url":null,"abstract":"<p><strong>Case series summary: </strong>This report describes two cats diagnosed with diabetes mellitus who developed clinical signs consistent with congestive heart failure (CHF). Clinical and echocardiographic findings improved over time with stabilisation and optimisation of glycaemic management. Both cats presented with dyspnoea, hypotension and hypothermia. Thoracic radiographs demonstrated diffuse pulmonary infiltrates. Pleural effusion was identified in one case. Echocardiography revealed left ventricular thickening with left atrial enlargement. Laboratory abnormalities included hyperglycaemia, elevated fructosamine and increased N-terminal pro B-type natriuretic peptide (NT-proBNP) concentrations. After CHF therapy and insulin administration, both cats showed rapid clinical improvement, with NT-proBNP concentrations decreasing into the reference interval and improvement in echocardiographic parameters within weeks. One cat later again showed an increase in myocardial thickness and experienced recurrence of CHF during a period of poor glycaemic control, with subsequent improvement after intensified glycaemic management.</p><p><strong>Relevance and novel information: </strong>To the authors' knowledge, this is the first report describing cats diagnosed with diabetes mellitus who developed CHF accompanied by increased left ventricular wall thickness and left atrial enlargement on echocardiography, with subsequent improvement after clinical stabilisation and glycaemic management. These cases suggest a potential association between metabolic dysregulation and the occurrence of CHF in cats.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"12 1","pages":"20551169261446703"},"PeriodicalIF":0.7,"publicationDate":"2026-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13213086/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148057347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Candida albicans</i> urinary tract infection in a cat treated with velagliflozin.","authors":"Jordi Clanxet Ballesteros, Luis Feo, Jordi Puig","doi":"10.1177/20551169261445535","DOIUrl":"10.1177/20551169261445535","url":null,"abstract":"<p><strong>Case summary: </strong>A 15-year-old, male neutered domestic shorthair cat presented with anuria due to urethral obstruction. The cat had a history of several urinary and systemic comorbidities at the time of presentation. Velagliflozin therapy had been started recently after a new diagnosis of diabetes mellitus. A mixed urinary tract infection caused by <i>Escherichia coli</i> and <i>Candida albicans</i> was diagnosed. The cat was initially managed with urinary catheterisation, antibiotics and antifungals, showing a favourable response. However, recurrent urinary obstruction occurred, requiring multiple urinary catheterisations. Approximately 2 weeks after presentation, urethral rupture was diagnosed using contrast urography. Urethrostomy was declined and the cat was ultimately euthanased.</p><p><strong>Relevance and novel information: </strong>The most frequent adverse effect reported in human patients treated with sodium-glucose cotransporter 2 inhibitors (SGLT2is) is mycotic genitourinary infection, particularly caused by <i>C albicans</i>. Several risk factors have been identified in humans; however, this association has not been previously demonstrated in cats. This is the first report describing a urinary tract infection caused by <i>C albicans</i> in a cat treated with velagliflozin. These findings emphasise the importance of monitoring for this potential adverse effect in cats receiving SGLT2is, particularly in those with comorbidities, and encourage further evaluation of SGLT2is as a putative risk factor for <i>C albicans</i> urinary tract infections in these patients.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"12 1","pages":"20551169261445535"},"PeriodicalIF":0.7,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13276204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148296759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of a three-dimensional-printed spine model for surgical planning in a feline vertebral chondroblastic osteosarcoma.","authors":"Anna Tauro, John Macri, Peter N McGinn, Abigail R Armwood, Tracy Gieger, Satyanarayana Konala, Christopher Mariani, Ola LA Harrysson","doi":"10.1177/20551169261445546","DOIUrl":"10.1177/20551169261445546","url":null,"abstract":"<p><strong>Case summary: </strong>A 2-year-old, male neutered domestic shorthair cat presented with a 1-month history of non-specific pain and inappetence, left-sided Horner syndrome, pelvic limb proprioceptive ataxia, upper motor neuron paraparesis and a plantigrade stance. Advanced imaging revealed a heterogeneous contrast-enhancing extradural mass dorsal to the T1-T2 intervertebral disc space, causing severe left-sided spinal cord compression. Medical image processing software was used to generate a patient-specific three-dimensional spine model based on MRI and CT data. A biomechanical three-dimensional-printed replica of the T1-T3 region allowed preoperative simulation of a left-sided hemilaminectomy and mass removal, confirming contiguity of the lesion with the T1 vertebral body and extension along the vertebral canal to T2-T3. The model aided intraoperative landmark identification and facilitated safe and effective spinal cord decompression. Histopathology from surgical biopsy was most consistent with either chondroblastic osteosarcoma or chondrosarcoma. Postoperative radiation therapy was initiated but discontinued owing to difficulties establishing reliable intravenous access. Progressive neurologic deterioration eventually led to euthanasia. Post-mortem CT and necropsy confirmed a diagnosis of chondroblastic osteosarcoma without evidence of metastatic disease. The cat had a survival time of 356 days after surgery (387 days from initial presentation).</p><p><strong>Relevance and novel information: </strong> This report describes the first known vertebral chondroblastic osteosarcoma in a cat. It highlights the value of biomechanical three-dimensional-printed spine models for preoperative planning in complex vertebral surgery and demonstrates that tumor debulking, even when combined with incomplete radiotherapy, can provide meaningful palliation and prolonged survival. Further studies are needed to define optimal treatment strategies and prognosis for feline vertebral osteosarcoma subtypes.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"12 1","pages":"20551169261445546"},"PeriodicalIF":0.7,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13167354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147942371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CT findings and outcome after nephrectomy as sole therapy for renal nephroblastoma in a cat.","authors":"Alexandra W Diamond, Janis M Lapsley, Rebecca Urion, Brian D Husbands","doi":"10.1177/20551169261446341","DOIUrl":"10.1177/20551169261446341","url":null,"abstract":"<p><strong>Case summary: </strong>A 1-year-old, neutered male domestic shorthair cat with a several-day history of anorexia and lethargy presented to The Ohio State University Veterinary Medical Center. On physical examination, a mass-like lesion was palpated in the mid-abdomen. Abdominal radiographs, ultrasound and contrast-enhanced CT revealed a mass-like lesion associated with the right kidney. Unilateral nephrectomy with removal of the mass in its entirety was performed as the sole treatment modality, and histopathology revealed a renal nephroblastoma. Postoperatively, the cat was re-evaluated every 3-6 months. The cat continues to do well more than 3 years since diagnosis, which is longer than most published cases.</p><p><strong>Relevance and novel information: </strong>This report aims to describe a case of feline nephroblastoma managed solely by surgical treatment, with an unexpectedly long survival time.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"12 1","pages":"20551169261446341"},"PeriodicalIF":0.7,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148144699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Presumed partial aplasia of the hypothalamus and pituitary gland causing central diabetes insipidus in an adult cat.","authors":"Fabienne Nadja Leuthard, Monique Wenger, Tobias Neuhaus, Gernot Scharf","doi":"10.1177/20551169261445125","DOIUrl":"10.1177/20551169261445125","url":null,"abstract":"<p><strong>Case summary: </strong>A 2-year-old castrated male domestic shorthair cat presented with severe lethargy, hyporexia, dehydration and poor body condition. The incidence of polyuria/polydipsia was unknown because of the presence of multiple other cats in the household. Laboratory findings revealed severe hypernatraemia, isosthenuria, haemoconcentration and moderate azotaemia. MRI of the head demonstrated partial hypoplasia/aplasia of the hypothalamus and pituitary gland, confirming congenital central diabetes insipidus; additional endocrine testing excluded other causes. Initial fluid therapy improved the azotaemia and stabilised the haematocrit; however, hypernatraemia persisted until desmopressin therapy was initiated. The cat was successfully managed in the long term with gradually titrated oral desmopressin, achieving normalisation of electrolytes.</p><p><strong>Relevance and novel information: </strong>This report details the first documented case of central diabetes insipidus in an adult cat, attributed to presumed partial aplasia of the hypothalamus and pituitary gland, with no other hormonal deficiencies.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"12 1","pages":"20551169261445125"},"PeriodicalIF":0.7,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13242560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148206396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First molecular detection of <i>Leishmania infantum</i> in a domestic cat from Costa Rica.","authors":"Jorge F Sánchez-Bermúdez, Emilia Pacheco, Ricardo García, Laura Achí, María J Zuniga-Moya, Marta C Bonilla, Gaby Dolz","doi":"10.1177/20551169261445126","DOIUrl":"10.1177/20551169261445126","url":null,"abstract":"<p><strong>Case summary: </strong> A 4-year-old, neutered male domestic cat was presented with an indolent, non-ulcerated and painless subcutaneous nodule on the left hindlimb. Abdominal ultrasonography revealed generalized lymphadenomegaly and splenomegaly with a honeycomb pattern. The cat tested negative for feline leukemia virus and feline immunodeficiency virus. Fine-needle aspiration of the lesion showed mixed inflammatory cells, including eosinophils and macrophages containing small intracytoplasmic basophilic inclusions considered suspicious for <i>Leishmania-</i>like organisms. The mass was surgically excised for histopathological and molecular evaluation. Histopathology demonstrated eosinophilic granulomatous inflammation with secondary furunculosis, without unequivocal visualization of amastigotes. Quantitative RT-PCR was positive for <i>Leishmania</i> species, and conventional PCR targeting the ITS-1 gene, followed by sequencing, showed 99.62% identity with <i>Leishmania infantum</i>. No anti<i>-Leishmania</i> treatment was administered because the lesion was completely excised, the cat remained clinically well and specific anti-<i>Leishmania</i> drugs are not readily accessible in Costa Rica. At the 7-month follow-up, no recurrence of the nodule was observed.</p><p><strong>Relevance and novel information: </strong>This report describes the first molecular detection of <i>L infantum</i> in a Costa Rican domestic cat and the first record from the country's Central Valley. The case highlights the diagnostic challenges of feline <i>Leishmania</i> infection and supports <i>Leishmania</i> infection among the differential diagnoses for feline cutaneous nodules in Central America. It also underlines the need for further studies on the epidemiological role of cats in a One Health context.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"12 1","pages":"20551169261445126"},"PeriodicalIF":0.7,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13269728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148273201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical treatment of type II atresia ani and rectocutaneous fistula in a male kitten.","authors":"Olivia Csirikova, Luis Alejandro Pérez López, Krizia Compagnone","doi":"10.1177/20551169261442342","DOIUrl":"10.1177/20551169261442342","url":null,"abstract":"<p><strong>Case summary: </strong>A 4-week-old, male domestic shorthair kitten presented with congenital abnormalities of the rectum and perineal region, including defecation through an aberrant opening within the scrotal area. Positive-contrast radiography and ultrasonography confirmed type II anal atresia with a ventral rectocutaneous fistula. An abnormally positioned urethra was also identified, coursing dorsally to the penile structure. Surgical transposition of the fistulous tract and reconstruction of the anal sphincter were performed using a fistula-flap technique to restore normal defecation. Recovery was uneventful, and spontaneous defecation resumed within 2 weeks. At a 20-month follow-up, the patient remained clinically well.</p><p><strong>Relevance and novel information: </strong>This case represents the first documented use of a fistula-flap technique to successfully correct type II atresia ani with rectocutaneous fistula in a male feline patient, demonstrating that the technique can be safely adapted to different anorectal malformation patterns.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"12 1","pages":"20551169261442342"},"PeriodicalIF":0.7,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13243757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148212343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcoglycanopathy with absent expression of all sarcoglycan proteins in a young cat with clinical features of feline hypertrophic muscular dystrophy.","authors":"Arian Doroudi, Anna Sirochman, Allison Mooney","doi":"10.1177/20551169261442339","DOIUrl":"10.1177/20551169261442339","url":null,"abstract":"<p><strong>Case summary: </strong>A 1-year-old, male castrated domestic shorthair cat presented for chronic mobility decline and muscle stiffness, first noted at 3 months of age, and persistently elevated serum creatine kinase levels (>19,000-53,000 IU/l). Clinical examination revealed macroglossia and selective hypertrophy of cervical and appendicular muscles. Neurologic evaluation indicated a myopathic gait without pain or neurologic deficits. Muscle biopsy was supportive of muscular dystrophy (MD) and immunohistochemistry demonstrated loss of the sarcoglycan complex with complete absence of all tested sarcoglycan proteins, consistent with a diagnosis of sarcoglycan-deficient MD. These findings contrast with prior feline reports that were mostly limited to reduction or absence of beta-sarcoglycan on immunostaining without overt clinical evidence of MD. A follow-up echocardiogram revealed mild to moderate right ventricular changes without indications for treatment. At 2 months after diagnosis, the patient remained clinically static, suggesting a relatively slow progression despite absent sarcoglycan expression.</p><p><strong>Relevance and novel information: </strong>This case represents the first reported feline sarcoglycanopathy characterized by the absence of all tested sarcoglycan subunits on immunohistochemistry and concurrent presentation of classic Duchenne-like MD signs, including macroglossia and muscular hypertrophy. It expands the phenotypic spectrum of muscular dystrophies in cats, underscoring parallels to limb-girdle muscular dystrophies in humans and dogs. Given the cat's static clinical course and diagnostic overlap with dystrophinopathies, this case suggests sarcoglycan-deficient MD in cats may present with a broader spectrum of severity than previously appreciated. The findings support the potential utility of feline sarcoglycanopathies, when phenotypically consistent with forms appreciated in other species, as spontaneous animal models for comparative medical research.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"12 2","pages":"20551169261442339"},"PeriodicalIF":0.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13389103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shoulder arthrodesis as a treatment for severe shoulder deformity secondary to septic arthritis in two cats.","authors":"Koichiro Arashima, Nobuo Kanno, Shuji Suzuki, Takuya Yogo, Yasuji Harada, Osamu Taguchi, Yasushi Hara","doi":"10.1177/20551169261441730","DOIUrl":"10.1177/20551169261441730","url":null,"abstract":"<p><strong>Case series summary: </strong>Two rescued juvenile cats with unilateral severe shoulder deformities (SDs) suspected to be secondary to septic arthritis were referred for further management. Comprehensive diagnostic evaluations confirmed SD with suspected septic arthritis in both cases. Because of the poor prognosis for preserving shoulder joint function, shoulder arthrodesis was performed to relieve pain and restore forelimb weightbearing ability. At 6 and 8 years postoperatively, both cats exhibited normal motor function in the affected limbs, no signs of lameness and maintained a good quality of life. No evidence of osteomyelitis or implant failure was noted. These findings suggest that arthrodesis may be a viable and effective long-term treatment option for irreparable shoulder joint disorders in cats.</p><p><strong>Relevance and novel information: </strong>Shoulder joint injuries and disorders are less common in cats than in dogs, and only a limited number of reports exist in the small animal orthopaedic literature. In clinical practice, SD in small animals is rarely documented, with few references regarding its aetiology and pathophysiology. This report presents two cases of SD in rescued cats, demonstrating that shoulder arthrodesis can be an effective treatment for irreparable feline shoulder joint disorders. To the best of our knowledge, this is the first report to describe long-term clinical and radiographic outcomes of shoulder arthrodesis in cats with SD.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"12 2","pages":"20551169261441730"},"PeriodicalIF":0.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13396552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ovarian remnant syndrome in a 2-year-old cat with inconclusive diagnostics.","authors":"Hayley Moore, Robyn Wilborn, Lily Lewis, Jey Koehler, Alan Conley, Diane Delmain","doi":"10.1177/20551169261441706","DOIUrl":"10.1177/20551169261441706","url":null,"abstract":"<p><strong>Case summary: </strong>A 2.5-year-old, spayed female domestic shorthair cat was evaluated for estrus-like behavior (lordosis, vocalization and rolling) occurring on a cyclical basis every 3 weeks. Clinical signs began 6 months after ovariohysterectomy and exploratory abdominal surgery was performed; no ovarian tissue was found. On evaluation at a referral hospital, serum anti-Müllerian hormone (AMH) concentration was 0.14 ng/ml, consistent with a spayed female, and serum progesterone concentration was 1.3 ng/ml, which is not consistent with the presence of active luteal tissue. The cat returned while exhibiting estrus behavior and 90% of the vaginal epithelial cells seen on vaginal cytology were superficial. Serum AMH concentration at that time was again within the interval consistent with a spayed female (0.10 ng/ml). Gonadorelin was administered to induce ovulation; 3 weeks later, serum progesterone concentration was measured at 1.6 ng/ml, not consistent with the presence of active luteal tissue. Exploratory abdominal surgery was performed and a small 2 mm piece of ovarian tissue was removed from near the location of the right ovarian pedicle. No estrus-like behavior was observed in the weeks after the surgery.</p><p><strong>Relevance and novel information: </strong>This case study demonstrates that a very small amount of ovarian tissue can produce enough estradiol to stimulate estrus behavior in the cat and induce cornification of the vaginal epithelium, yet produce too little AMH to confirm its presence. Similarly, despite the formation and presence of luteal tissue, there was apparently too little progesterone secretion to confirm what is generally seen in an intact queen.</p>","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"12 1","pages":"20551169261441706"},"PeriodicalIF":0.7,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13168725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147943077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}