Journal of Feline Medicine and Surgery Open Reports最新文献_第4页

Clinicopathologic features and clinical outcome in a cat with nodal T-zone lymphoma. 猫淋巴结t区淋巴瘤的临床病理特征和临床转归。

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Journal of Feline Medicine and Surgery Open Reports Pub Date : 2025-04-18 eCollection Date: 2025-01-01 DOI: 10.1177/20551169251329189

Amanda K Midkiff, Matthew R Cook, William Vernau, Brian D Husbands

{"title":"Clinicopathologic features and clinical outcome in a cat with nodal T-zone lymphoma.","authors":"Amanda K Midkiff, Matthew R Cook, William Vernau, Brian D Husbands","doi":"10.1177/20551169251329189","DOIUrl":"https://doi.org/10.1177/20551169251329189","url":null,"abstract":"Case summary: An 11-year-old male castrated domestic shorthair cat presented with increased respiratory effort, pleural effusion, lymphadenopathy, lethargy and decreased appetite with weight loss. A diagnosis of T-zone lymphoma was made from histopathology of an extirpated popliteal lymph node that had a marked paracortical expansion of small lymphocytes and prominent high endothelial venule proliferation. T-cell receptor gamma (TRG) molecular clonality PCR yielded a clonal rearrangement and immunohistochemistry demonstrated that the neoplastic lymphocytes expressed CD3 and did not express CD20. The cat was initially treated with two doses of intravenous vincristine and oral prednisolone followed by oral chlorambucil. The pleural effusion, lymphadenopathy, lymphocytosis, abdominal organomegaly and lethargy resolved, and the cat's appetite and body weight returned to normal. At the time of manuscript submission, the cat continued to do well, more than 24 months after presentation.Relevance and novel information: T-zone lymphoma is a common indolent lymphoma in dogs, but it has only been histopathologically described in one cat before this report. This is the first report to describe the clinical presentation, clinicopathologic findings and outcome for a cat with T-zone lymphoma.","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"11 1","pages":"20551169251329189"},"PeriodicalIF":0.7,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral haematomas as the major presenting sign of primary immune thrombocytopenia in a cat. 口腔血肿是猫原发性免疫性血小板减少症的主要表现。

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Journal of Feline Medicine and Surgery Open Reports Pub Date : 2025-04-16 eCollection Date: 2025-01-01 DOI: 10.1177/20551169251326784

Lidia Cammack, Annabel Sutch, Yan Ru Choi, Vanessa R Barrs, Julia A Beatty

{"title":"Oral haematomas as the major presenting sign of primary immune thrombocytopenia in a cat.","authors":"Lidia Cammack, Annabel Sutch, Yan Ru Choi, Vanessa R Barrs, Julia A Beatty","doi":"10.1177/20551169251326784","DOIUrl":"https://doi.org/10.1177/20551169251326784","url":null,"abstract":"Case summary: An unowned, entire male domestic shorthair cat was surrendered to a rescue centre. On physical examination, poor body condition (score 3/9) and pigmented mass lesions on the lateral aspects of the upper gingivae were noted. The oral lesions were identified as haematomas only after examination under sedation. A diagnosis of probable primary immune thrombocytopenia (pITP) was made based on profound thrombocytopenia, rapid response to glucocorticoid therapy and the absence of identified triggers for secondary immune thrombocytopenia. The patient was treated with glucocorticoids and remained in remission 18 months from diagnosis.Relevance and novel information: pITP is infrequently reported in cats and oral haematomas have not previously been documented as a presenting clinical sign. This case report serves to raise awareness of feline ITP and highlights the availability of evidence-based diagnostic and therapeutic guidelines that were published after the case was treated. While pITP can be refractory to treatment and can be associated with treatment-related morbidity, this case report demonstrates that an acceptable outcome can be achieved, albeit with a requirement for long-term treatment and regular monitoring.","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"11 1","pages":"20551169251326784"},"PeriodicalIF":0.7,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyalinizing pancreatic adenocarcinoma in a cat. 猫的透明化胰腺腺癌。

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Journal of Feline Medicine and Surgery Open Reports Pub Date : 2025-04-16 eCollection Date: 2025-01-01 DOI: 10.1177/20551169251325333

Taylor C Chan, Elisa Heacock, Ashleigh Cournoyer, Koranda Walsh, Amy C Durham

{"title":"Hyalinizing pancreatic adenocarcinoma in a cat.","authors":"Taylor C Chan, Elisa Heacock, Ashleigh Cournoyer, Koranda Walsh, Amy C Durham","doi":"10.1177/20551169251325333","DOIUrl":"https://doi.org/10.1177/20551169251325333","url":null,"abstract":"Case summary: A 6-year-old female spayed domestic shorthair cat was presented for abdominal distension and weight loss. Abdominal radiographs and ultrasound revealed two cranial abdominal masses and another mass adjacent to the jejunum. Cytologic features of the cranial abdominal masses were consistent with exocrine pancreatic tissue. Four months later, a repeat abdominal ultrasound revealed progressive enlargement of the abdominal masses and medial iliac lymphadenopathy. On exploratory laparotomy, two abdominal masses were associated with the pancreas and incorporated large blood vessels supplying the liver, pancreas and spleen. The masses were non-resectable and incisional biopsies were obtained. The histologic features were diagnostic for a hyalinizing subtype of exocrine pancreatic adenocarcinoma. Chemotherapy was not pursued. Over 28 months after the initial detection of abdominal masses, the cat was still alive and reportedly doing well.Relevance and novel information: To the authors' knowledge, this is the first report of a hyalinizing subtype of pancreatic adenocarcinoma in a cat. This subtype is considered to behave less aggressively in dogs, and this case may support that a similar, more indolent behavior may be seen in cats.","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"11 1","pages":"20551169251325333"},"PeriodicalIF":0.7,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033424/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of a pleural access port in the staged management of idiopathic chylothorax in a cat. 胸膜通道在猫特发性乳糜胸分期治疗中的应用。

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Journal of Feline Medicine and Surgery Open Reports Pub Date : 2025-04-12 eCollection Date: 2025-01-01 DOI: 10.1177/20551169251326747

Kaitlin N Bahlmann, Bryden J Stanley

{"title":"Use of a pleural access port in the staged management of idiopathic chylothorax in a cat.","authors":"Kaitlin N Bahlmann, Bryden J Stanley","doi":"10.1177/20551169251326747","DOIUrl":"https://doi.org/10.1177/20551169251326747","url":null,"abstract":"Case summary: A 4-year-old male castrated domestic shorthair cat presented with a 3-month history of coughing and progressive dyspnea. The cat was diagnosed with idiopathic chylothorax after serum biochemistry, thoracocentesis, cytology of pleural effusion, echocardiography and thoracic imaging were performed. After failure to respond to medical management with repeated thoracocenteses, the oral administration of rutin and a low-fat diet, the cat underwent staged interventions consisting of CT lymphangiogram, subtotal pericardiectomy and pleural access port (PAP) placement, followed by thoracic duct ligation (TDL) and cisterna chyli ablation (CCA) 2 months later. The cat made a clinical recovery based on resolution of chylous pleural effusion 1 month after TDL and CCA, and the PAP was removed 1 month later. The cat remained free of clinical signs 3 years postoperatively.Relevance and novel information: This is the first report documenting the use of a PAP for the management of feline chylothorax to disease resolution. Employing this device enabled frequent, low morbidity drainage of the pleural effusion as an alternative to repeated thoracocenteses and facilitated staging the interventions throughout management of idiopathic chylothorax in a cat. PAPs can be used successfully in the management of chylous pleural effusion in cats.","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"11 1","pages":"20551169251326747"},"PeriodicalIF":0.7,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful management of pemphigus foliaceus with mycophenolate mofetil as a steroid-sparing agent in a cat with corticosteroid-associated congestive heart failure. 用霉酚酸酯作为类固醇保留剂成功治疗伴有皮质类固醇相关充血性心力衰竭的猫的叶状天疱疮。

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Journal of Feline Medicine and Surgery Open Reports Pub Date : 2025-04-02 eCollection Date: 2025-01-01 DOI: 10.1177/20551169251321376

Giulia Striuli, Sophie Vandenabeele, Margot Gheeraert, Pascale Smets

{"title":"Successful management of pemphigus foliaceus with mycophenolate mofetil as a steroid-sparing agent in a cat with corticosteroid-associated congestive heart failure.","authors":"Giulia Striuli, Sophie Vandenabeele, Margot Gheeraert, Pascale Smets","doi":"10.1177/20551169251321376","DOIUrl":"10.1177/20551169251321376","url":null,"abstract":"Case summary: A 5-year-old British Shorthair cat was diagnosed with pemphigus foliaceus (PF) and was initially treated with methylprednisolone (0.7 mg/kg q12h), which possibly resulted in congestive heart failure (CHF). Treatment was switched to dexamethasone (0.09 mg/kg q24h) and mycophenolate mofetil (MMF) (10 mg/kg q12h) was added as a steroid-sparing agent. Although dexamethasone was slowly tapered off, MMF alone successfully maintained PF in remission. After 15 weeks of treatment, blood tests showed neutropenia and thrombocytopaenia. MMF dose reduction (10 mg/kg q24h) resulted in the normalisation of haematological parameters, although a mild flare of PF occurred. The reintroduction of dexamethasone (0.09 mg/kg twice weekly) rapidly restored disease control. MMF (10 mg/kg q24h) and dexamethasone (0.045 mg/kg twice weekly) were continued as maintenance therapy. After 36 weeks, the cat remained in clinical remission without further complications.Relevance and novel information: To the best of the authors' knowledge, this is the first case report to describe the use of MMF in a cat with PF. MMF was well tolerated and it was able to manage clinical signs even after the discontinuation of corticosteroids. Since mild and reversible haematological abnormalities were observed, careful monitoring during MMF administration is recommended. In this case, MMF dose reductions led to flares requiring a temporary reintroduction of corticosteroids to maintain disease control. MMF could be useful as an alternative treatment in cats affected by comorbidities where corticosteroid monotherapy would pose risks.","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"11 1","pages":"20551169251321376"},"PeriodicalIF":0.7,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Point-of-care ClotPro thromboelastography to determine bleeding risk in two cats with factor XII deficiency. 点护理ClotPro血栓弹性成像确定出血风险的两只猫与因子十二缺乏症。

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Journal of Feline Medicine and Surgery Open Reports Pub Date : 2025-03-31 eCollection Date: 2025-01-01 DOI: 10.1177/20551169251319138

Vera Forer, Pavlos G Doulidis, Verena Steiner, Natali Bauer, Lisa Maria Kulmer, Nicole Luckschander-Zeller

{"title":"Point-of-care ClotPro thromboelastography to determine bleeding risk in two cats with factor XII deficiency.","authors":"Vera Forer, Pavlos G Doulidis, Verena Steiner, Natali Bauer, Lisa Maria Kulmer, Nicole Luckschander-Zeller","doi":"10.1177/20551169251319138","DOIUrl":"10.1177/20551169251319138","url":null,"abstract":"Case series summary: Factor XII (FXII) deficiency is a rare autosomal recessive genetic disorder in cats, leading to singular prolonged activated partial thromboplastin clotting time (aPTT) without increased bleeding risk. This case series describes two cats diagnosed with FXII deficiency using the ClotPro system, a point-of-care viscoelastic coagulation test. Both cats exhibited significantly prolonged aPTT and intrinsic pathway clotting time but maintained normal clot strength, as indicated by thromboelastography (TEG). FXII deficiency was confirmed through quantitative ELISA measurement. Despite prolonged clotting times, the cats did not demonstrate clinical bleeding, suggesting that FXII deficiency does not increase bleeding risk. However, larger controlled studies are necessary to further investigate the utility of TEG in cats with FXII deficiency or other coagulation disorders.Relevance and novel information: This study addresses the diagnostic challenges associated with FXII deficiency, a condition that can lead to misinterpretation of coagulation results and unnecessary treatments. It highlights the application of the ClotPro system in feline medicine, providing deeper insights into coagulation dynamics and confirming that FXII deficiency does not inherently increase bleeding risk despite prolonged clotting times.","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"11 1","pages":"20551169251319138"},"PeriodicalIF":0.7,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11960162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful treatment of atypical hypoadrenocorticism in a cat presenting with hypoglycaemic seizures. 成功治疗不典型肾上腺皮质激素减退症在猫表现为低血糖发作。

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Journal of Feline Medicine and Surgery Open Reports Pub Date : 2025-03-29 eCollection Date: 2025-01-01 DOI: 10.1177/20551169251319945

Emily Madden, Briannan-Kym Deguara

{"title":"Successful treatment of atypical hypoadrenocorticism in a cat presenting with hypoglycaemic seizures.","authors":"Emily Madden, Briannan-Kym Deguara","doi":"10.1177/20551169251319945","DOIUrl":"10.1177/20551169251319945","url":null,"abstract":"Case summary: A 4-year-old male castrated Ragdoll cat presented for generalised seizures. The cat displayed hyporexia, lethargy and hiding behaviour 24-48 h before presentation. The cat had a chronic history of daily vomiting and tachypnoea for 12 months. Severe hypoglycaemia was noted at 1.8 mmol/l (reference interval 4.11-8.84) on initial presentation. The hypoglycaemia persisted despite multiple glucose boluses, resulting in the cat being treated with a glucose and glucagon continuous rate infusion. The cat underwent extensive diagnostic evaluation during hospitalisation, consisting of serial venous blood gas assessment, haematology and biochemistry analysis, urinalysis, serum insulin assay, resting cortisol, adrenocorticotropic hormone (ACTH) stimulation test, abdominal and thoracic imaging, and airway culture. A resting cortisol level of <14 nmol/l was obtained on day 2 of hospitalisation with a follow-up ACTH-stimulation test reporting a baseline cortisol of <28 nmol/l and a 1 h post-ACTH cortisol of 7 nmol/l, supporting a diagnosis of hypoadrenocorticism. The cat was successfully treated with glucocorticoid therapy and discharged home 8 days after initial presentation.Relevance and novel information: There are limited cases of feline hypoadrenocorticism present in the literature, most of which describe cats with both glucocorticoid and mineralocorticoid deficiency. Only two previous case reports of feline atypical hypoadrenocorticism exist. Only one of these case reports describes hypoglycaemia with signs of neuroglycopaenia on initial presentation. To the author's knowledge, this is the first successfully treated case of atypical hypoadrenocorticism presenting with hypoglycaemic seizures in a cat, demonstrating successful long-term management.","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"11 1","pages":"20551169251319945"},"PeriodicalIF":0.7,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasonographic features of double intestinal intussusception in a cat. 猫双肠套叠的超声特征。

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Journal of Feline Medicine and Surgery Open Reports Pub Date : 2025-03-28 eCollection Date: 2025-01-01 DOI: 10.1177/20551169251316999

Stefano Ludovici, Anna Cronin, Domenico Sainato

引用次数: 0

Primary polydipsia in a cat. 猫原发性多饮。

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Journal of Feline Medicine and Surgery Open Reports Pub Date : 2025-03-23 eCollection Date: 2025-01-01 DOI: 10.1177/20551169241311680

Jihyun Kim, Sooa Yoon, Miryeng Kim, Seungjin Lee, Woojin Song, Youngmin Yun

{"title":"Primary polydipsia in a cat.","authors":"Jihyun Kim, Sooa Yoon, Miryeng Kim, Seungjin Lee, Woojin Song, Youngmin Yun","doi":"10.1177/20551169241311680","DOIUrl":"10.1177/20551169241311680","url":null,"abstract":"Case summary: In cats, polyuria (PU) and polydipsia (PD) are defined as a urine specific gravity (USG) consistently <1.035 and water consumption >100 ml/kg/day. A 2-year-old castrated male domestic shorthair cat with PU/PD was brought to our hospital. Diagnostic tests for PU/PD included physical examination, blood analyses (complete blood count, serum chemistry profile, electrolytes, ionised calcium, symmetric dimethylarginine and thyroxine concentration), thoracic radiography, abdominal ultrasound examination, urinalysis, urine cortisol:creatinine ratio, urine protein:creatinine ratio and urine culture. A modified water deprivation test resulted in a USG >1.036 and cranial MRI did not identify any abnormalities. Therefore, the cat was administered desmopressin, which failed to decrease water consumption or increase the USG above the untreated level; thus, primary PD was confirmed.Relevance and novel information: This rare case of feline primary PD is the first reported that did not identify evidence of structural pathology of the pituitary gland.","PeriodicalId":36588,"journal":{"name":"Journal of Feline Medicine and Surgery Open Reports","volume":"11 1","pages":"20551169241311680"},"PeriodicalIF":0.7,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thoracoscopic-assisted surgical stabilisation with a locking compression plate for pectus excavatum in a Maine Coon kitten. 胸腔镜辅助下用锁定加压钢板固定缅因猫漏斗胸。

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Journal of Feline Medicine and Surgery Open Reports Pub Date : 2025-03-22 eCollection Date: 2025-01-01 DOI: 10.1177/20551169251314253

Giorgia Venzo, Stéphane Libermann

引用次数: 0