iScience最新文献_第8页

Dirac-Rashba fermions and quantum valley Hall insulators in graphene-based 2D heterostructures 石墨烯二维异质结构中的Dirac-Rashba费米子和量子谷霍尔绝缘子

IF 4.6 2区综合性期刊

iScience Pub Date : 2025-06-04 DOI: 10.1016/j.isci.2025.112818

Bo-Wen Yu , Bang-Gui Liu

{"title":"Dirac-Rashba fermions and quantum valley Hall insulators in graphene-based 2D heterostructures","authors":"Bo-Wen Yu , Bang-Gui Liu","doi":"10.1016/j.isci.2025.112818","DOIUrl":"10.1016/j.isci.2025.112818","url":null,"abstract":"<div><div>For promising Dirac electronic properties and functionalities, we study five 2D heterostructures consisting of graphene and monolayer transition metal dichalcogenides by means of first-principles investigation and an effective low-energy model. It is revealed from first-principles bands that the Dirac energy bands are gapped (0.1 <span><math><mrow><mo>∼</mo></mrow></math></span> 0.5 meV) and their relativistic dispersions are robust up to the energy window of 0.4 eV at least. The model parameters are determined by fitting the first-principles calculated bands in each of the heterostructures. It is shown that Dirac-Rashba fermions are hosted in the <span><math><mrow><msub><mtext>WSe</mtext><mn>2</mn></msub></mrow></math></span>/graphene and <span><math><mrow><msub><mtext>MoSe</mtext><mn>2</mn></msub></mrow></math></span>/graphene/WSe<sub>2</sub>, and quantum valley Hall insulators can be achieved in all these heterostructures. Further analysis elucidates features of Berry curvature distribution and interactions of the orbitals and spins. These can be useful in future exploration for more effects and functionalities in 2D heterostructures.</div></div>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 7","pages":"Article 112818"},"PeriodicalIF":4.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Theta-encoded information flow from dorsal CA1 to prelimbic cortex drives memory reconsolidation 从背侧CA1到前边缘皮层的theta编码信息流驱动记忆再巩固

IF 4.6 2区综合性期刊

iScience Pub Date : 2025-06-04 DOI: 10.1016/j.isci.2025.112821

Andressa Radiske , María Carolina Gonzalez , Janine I. Rossato , Sergio Conde-Ocazionez , Martín Cammarota

{"title":"Theta-encoded information flow from dorsal CA1 to prelimbic cortex drives memory reconsolidation","authors":"Andressa Radiske , María Carolina Gonzalez , Janine I. Rossato , Sergio Conde-Ocazionez , Martín Cammarota","doi":"10.1016/j.isci.2025.112821","DOIUrl":"10.1016/j.isci.2025.112821","url":null,"abstract":"<div><div>Reconsolidation is the process by which reactivated, labile memories are restabilized. Disrupting this process induces retrograde amnesia specific to the reactivated memory, making it a promising therapeutic target for anxiety disorders rooted in maladaptive avoidance. However, the electrophysiological mechanisms underlying reconsolidation are still not fully understood, limiting its translational potential. Here, we show that inducing reconsolidation of a fear-driven avoidance memory in adult male rats increases coherent theta synchrony and directional connectivity between the dorsal CA1 region of the hippocampus and the prelimbic cortex. Optogenetic silencing of dorsal CA1 terminals in the prelimbic cortex during the reconsolidation induction window disrupted this theta coupling and led to delayed memory impairment. These findings demonstrate that reconsolidation depends on theta-mediated information transfer through the direct dorsal CA1-prelimbic pathway and suggest that monitoring or modulating this activity could inform the development of targeted interventions aimed to modify or disrupt distressing, intrusive memories.</div></div>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 7","pages":"Article 112821"},"PeriodicalIF":4.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resonant inelastic X-ray scattering for studying materials for renewable energy conversion and storage 研究可再生能源转换和储存材料的非弹性x射线共振散射

IF 4.6 2区综合性期刊

iScience Pub Date : 2025-06-04 DOI: 10.1016/j.isci.2025.112820

Rongfu Hong , Lixin Xing , Mingjie Wu , Zhangsen Chen , Ning Wang , Ling Meng , Siyu Ye , Liguang Wang , Gaixia Zhang , Lei Du

{"title":"Resonant inelastic X-ray scattering for studying materials for renewable energy conversion and storage","authors":"Rongfu Hong , Lixin Xing , Mingjie Wu , Zhangsen Chen , Ning Wang , Ling Meng , Siyu Ye , Liguang Wang , Gaixia Zhang , Lei Du","doi":"10.1016/j.isci.2025.112820","DOIUrl":"10.1016/j.isci.2025.112820","url":null,"abstract":"<div><div>Renewable energy conversion and storage technologies, including batteries, fuel cells, and electrolyzers, have garnered global attention. Electrode materials are crucial in determining the performance and lifespan of the corresponding devices. Transition metals and light elements are key components in electrode materials, enabling efficient energy conversion by directly providing active sites or indirectly optimizing material electronic structures. To understand the relationship between electronic structures and device performance, advanced techniques like X-ray absorption spectroscopy (XAS) have been developed. Recently, resonant inelastic X-ray scattering (RIXS) features coupled with X-ray emission spectra (XES) have emerged as a complementary tool, providing additional insights into material electronic structures. This review focuses on recent advances in using XES, particularly RIXS, for studying energy conversion and storage materials, highlighting the unique features and potential of RIXS for electronic structure characterization and quantitative analysis. This work aims to stimulate interests in utilizing RIXS features in the field of energy conversion and storage.</div></div>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 7","pages":"Article 112820"},"PeriodicalIF":4.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

B cell-derived nociceptin/orphanin FQ contributes to impaired glucose tolerance and insulin resistance in obesity B细胞来源的伤害肽/孤啡肽FQ有助于肥胖患者的葡萄糖耐量受损和胰岛素抵抗

IF 4.6 2区综合性期刊

iScience Pub Date : 2025-06-04 DOI: 10.1016/j.isci.2025.112819

Stephanie C. Puente-Ruiz , Leona Ide , Julia Schuller , Adel Ben-Kraiem , Anne Hoffmann , Adhideb Ghosh , Falko Noé , Christian Wolfrum , Kerstin Krause , Martin Gericke , Nora Klöting , Jens C. Brüning , F. Thomas Wunderlich , Matthias Blüher , Alexander Jais

{"title":"B cell-derived nociceptin/orphanin FQ contributes to impaired glucose tolerance and insulin resistance in obesity","authors":"Stephanie C. Puente-Ruiz , Leona Ide , Julia Schuller , Adel Ben-Kraiem , Anne Hoffmann , Adhideb Ghosh , Falko Noé , Christian Wolfrum , Kerstin Krause , Martin Gericke , Nora Klöting , Jens C. Brüning , F. Thomas Wunderlich , Matthias Blüher , Alexander Jais","doi":"10.1016/j.isci.2025.112819","DOIUrl":"10.1016/j.isci.2025.112819","url":null,"abstract":"<div><div>Immune-derived opioid peptides have been implicated in immune regulation and inflammatory processes. Here, we investigate the effects of nociceptin/orphanin FQ (N/OFQ) on metabolic function and inflammation in obesity. Selectively targeting N/OFQ, encoded by the <em>Pnoc</em> gene, in B cells mitigates the adverse metabolic effects of diet-induced obesity and enhances insulin sensitivity and glucose tolerance. Notably, B cell-specific <em>Pnoc</em> knockout mice display a marked reduction in markers of immune cell migration and diminished macrophage recruitment in adipose tissue and liver. Mechanistically, we identify that N/OFQ promotes macrophage recruitment and metabolic inflammation, exacerbating glucose intolerance and insulin resistance during obesity. Overall, the immunomodulatory properties exhibited by the N/OFQ-NOP system render it a promising therapeutic target for mitigating metabolic inflammation.</div></div>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 7","pages":"Article 112819"},"PeriodicalIF":4.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of air pollution and occupational inhalation exposures on neurodegenerative disorders: An epigenetic perspective 空气污染和职业性吸入暴露对神经退行性疾病的影响：一个表观遗传学的观点

IF 4.6 2区综合性期刊

iScience Pub Date : 2025-06-04 DOI: 10.1016/j.isci.2025.112825

Paola Monti , Elia Biganzoli , Valentina Bollati

{"title":"Impact of air pollution and occupational inhalation exposures on neurodegenerative disorders: An epigenetic perspective","authors":"Paola Monti , Elia Biganzoli , Valentina Bollati","doi":"10.1016/j.isci.2025.112825","DOIUrl":"10.1016/j.isci.2025.112825","url":null,"abstract":"<div><div>Neurodegenerative disorders (NDs) are highly prevalent conditions with genetic and environmental causes. Recently, air pollution has emerged as an important contributor to NDs, causing oxidative stress and neuronal damage in the brain. Identifying early molecular alterations mediating the effects of air pollution on ND pathogenesis would be crucial for implementing personalized medicine approaches, especially for the monitoring of specific categories of highly exposed workers. Epigenetic modifications might be suitable candidates in that sense, since they are highly responsive to environmental stressors, they modulate the expression of multiple ND-related genes, and offer technical advantages as they can be studies in peripheral tissues and are relatively stable in biological samples after collection.</div><div>In this review, we summarize the current knowledge regarding the association between air pollution inhalation, epigenetics, and NDs. This work will particularly emphasize research gaps, aiming to provide directions for future research with applications in occupational and preventive medicine.</div></div>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 7","pages":"Article 112825"},"PeriodicalIF":4.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144297191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bispecific targeting of 4-1BB and CCR8 boosts antitumor immunity via Ti-Treg depletion and CD8+ activation 双特异性靶向4-1BB和CCR8通过Ti-Treg消耗和CD8+激活增强抗肿瘤免疫

IF 4.6 2区综合性期刊

iScience Pub Date : 2025-06-04 DOI: 10.1016/j.isci.2025.112829

Jiefang Xu , Ran Wang , Shipeng Cheng , Sonam Wangmo , Jichao Yang , Fuquan Jin , Xiao Lu , Liyan Ma , Ying Zhu , Haoting Sun , Lunxiu Qin , Zhiyang Ling , Yaguang Zhang , Xiaoyu Sun , Chunyan Yi , Bing Sun

{"title":"Bispecific targeting of 4-1BB and CCR8 boosts antitumor immunity via Ti-Treg depletion and CD8+ activation","authors":"Jiefang Xu , Ran Wang , Shipeng Cheng , Sonam Wangmo , Jichao Yang , Fuquan Jin , Xiao Lu , Liyan Ma , Ying Zhu , Haoting Sun , Lunxiu Qin , Zhiyang Ling , Yaguang Zhang , Xiaoyu Sun , Chunyan Yi , Bing Sun","doi":"10.1016/j.isci.2025.112829","DOIUrl":"10.1016/j.isci.2025.112829","url":null,"abstract":"<div><div>Immune checkpoint therapy has transformed cancer treatment, yet efficacy and safety challenges persist. Selectively inhibiting tumor-infiltrating regulatory T cells (Ti-Tregs) while enhancing CD8<sup>+</sup> T cell function are complementary strategies in cancer immunotherapy. Here, we engineered a bispecific antibody, FRP303, targeting 4-1BB and CCR8, which are co-expressed on a highly immunosuppressive subset of Ti-Tregs. <em>In vivo,</em> FRP303 outperformed monoclonal antibodies in CT26 and MC38 colorectal tumors and poorly immunogenic B16F10 melanoma. Treatment with FRP303 reduced Ti-Treg frequency, increased CD8<sup>+</sup> T cell infiltration, and elevated antitumor cytokines IFN-γ and TNF-α. Safety assessments showed FRP303 does not disrupt immune homeostasis in peripheral tissues or induce significant hepatotoxicity. Moreover, FRP303 demonstrated strong synergistic effects when combined with a PD-1 antibody. In summary, FRP303 mediated anti-tumor activity through a dual mechanism involving the selective depletion of Ti-Tregs and the enhancement of CD8<sup>+</sup> T cell function, offering a promising strategy for cancer immunotherapy.</div></div>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 7","pages":"Article 112829"},"PeriodicalIF":4.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetically encoded and modular subcellular organelle probes reveal dysfunction in lysosomes and mitochondria driven by PRKN knockout 基因编码和模块化亚细胞细胞器探针揭示了PRKN敲除驱动的溶酶体和线粒体功能障碍

IF 4.6 2区综合性期刊

iScience Pub Date : 2025-06-03 DOI: 10.1016/j.isci.2025.112816

Camille Goldman , Tatyana Kareva , Lily Sarrafha , Braxton R. Schuldt , Abhishek Sahasrabudhe , Tim Ahfeldt , Joel W. Blanchard

{"title":"Genetically encoded and modular subcellular organelle probes reveal dysfunction in lysosomes and mitochondria driven by PRKN knockout","authors":"Camille Goldman , Tatyana Kareva , Lily Sarrafha , Braxton R. Schuldt , Abhishek Sahasrabudhe , Tim Ahfeldt , Joel W. Blanchard","doi":"10.1016/j.isci.2025.112816","DOIUrl":"10.1016/j.isci.2025.112816","url":null,"abstract":"<div><div>Cellular processes including lysosomal and mitochondrial dysfunction are implicated in the development of many diseases. Quantitative visualization of mitochondria and lysosomes is crucial to understand how these organelles are dysregulated during disease. To address a gap in live-imaging tools, we developed GEM-SCOPe (genetically encoded and modular subcellular organelle probes), a modular toolbox of fluorescent markers designed to inform on localization, distribution, turnover, and oxidative stress of specific organelles. We expressed GEM-SCOPe in differentiated astrocytes and neurons from a human pluripotent stem cell <em>PRKN-</em>knockout model of Parkinson’s disease and identified disease-associated changes in proliferation, lysosomal distribution, mitochondrial transport and turnover, and reactive oxygen species. We demonstrate GEM-SCOPe is a powerful panel that provides critical insight into the subcellular mechanisms underlying Parkinson’s disease in human cells. GEM-SCOPe can be expanded upon and applied to a diversity of cellular models to glean an understanding of the mechanisms that promote disease onset and progression.</div></div>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 7","pages":"Article 112816"},"PeriodicalIF":4.6,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolomic and microbial insights: Kai-Xin-San’s impact on Alzheimer’s disease pathology 代谢组学和微生物学见解：开心散对阿尔茨海默病病理的影响

IF 4.6 2区综合性期刊

iScience Pub Date : 2025-06-03 DOI: 10.1016/j.isci.2025.112817

Huifen Ma , Zhiyang Yu , Qiong Qiao , Wenpan Wang , Zhonghua Li , Pan Wang , Junying Song , Xiaowei Zhang , Yunfang Su , Yiran Sun , Zhishen Xie , Zhenqiang Zhang

{"title":"Metabolomic and microbial insights: Kai-Xin-San’s impact on Alzheimer’s disease pathology","authors":"Huifen Ma , Zhiyang Yu , Qiong Qiao , Wenpan Wang , Zhonghua Li , Pan Wang , Junying Song , Xiaowei Zhang , Yunfang Su , Yiran Sun , Zhishen Xie , Zhenqiang Zhang","doi":"10.1016/j.isci.2025.112817","DOIUrl":"10.1016/j.isci.2025.112817","url":null,"abstract":"<div><div>There has been increasing interest in the connection between AD, gut microbiota, and metabolites. Kai-Xin-San (KXS) has been commonly employed in ancient and modern Chinese clinical trials for the treatment of dementia; however, whether the protective effect of KXS in AD is related to the gut microbiota remains elusive. APP/PS1 mice were used as the model of AD. 43 key metabolites influenced by KXS were screened using untargeted metabolomics. At the genus level, Clostridium_IV, Eubacterium, Acetatifactor, etc., were identified to be impacted by KXS using 16S rRNA sequencing. Additionally, we identified 9 distinct intestinal floras at the genus level that were correlated with 13 pivotal differential metabolites related to cognitive impairment. KXS also inhibited the neuroinflammation, mostly via regulating the key metabolites. A potential relationship between gut microbiota, metabolites, and neuroinflammation is suggested as a protective mechanism of KXS in AD. These findings provide support for further development of KXS.</div></div>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 7","pages":"Article 112817"},"PeriodicalIF":4.6,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144291696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Myopic versus perfect foresight target setting for Indonesia’s net zero electricity transition 印尼净零电力转型的短视与完美远见目标设定

IF 4.6 2区综合性期刊

iScience Pub Date : 2025-06-02 DOI: 10.1016/j.isci.2025.112813

Bintang Yuwono , Lukas Kranzl , Reinhard Haas , Ping Yowargana

{"title":"Myopic versus perfect foresight target setting for Indonesia’s net zero electricity transition","authors":"Bintang Yuwono , Lukas Kranzl , Reinhard Haas , Ping Yowargana","doi":"10.1016/j.isci.2025.112813","DOIUrl":"10.1016/j.isci.2025.112813","url":null,"abstract":"<div><div>In the effort to align with Paris goals, decision-makers set targets that usually concern milestones earlier than 2100. These targets can be derived from different considerations of long-term implications of actions. This study investigates the implications of deciding on emissions targets based on myopic vis-à-vis perfect foresight using long-term energy system optimization model. The study reveals cost discrepancies correspond to the gaps between emissions derived from mixed integer linear programming (MILP) solution in perfect foresight scenarios versus exogenous values in myopic scenarios. When considering myopic approach, our study suggests that avoiding drastic emissions reduction can deliver minimum cost discrepancies relative to what can be achieved with perfect foresight. However, this poses a dilemma where less drastic emissions targets may risk increasing fossil power generation under lenient emissions reduction targets. Complementing less drastic emissions reduction targets with more ambitious policies promoting renewables is necessary to avoid the risk of increased reliance on fossil power generation.</div></div>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 7","pages":"Article 112813"},"PeriodicalIF":4.6,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Boron concentration drives boron substructure and properties derivation in manganese borides 硼浓度驱动硼化物中硼的亚结构和性质派生

IF 4.6 2区综合性期刊

iScience Pub Date : 2025-06-02 DOI: 10.1016/j.isci.2025.112803

Shuailing Ma , Yuyue Pang , Kuo Bao , Min Lian , Shuying Wu , Chunyan Zhao , Chunhong Xu , Qiang Tao , Xingbin Zhao , Pinwen Zhu , Tian Cui

{"title":"Boron concentration drives boron substructure and properties derivation in manganese borides","authors":"Shuailing Ma , Yuyue Pang , Kuo Bao , Min Lian , Shuying Wu , Chunyan Zhao , Chunhong Xu , Qiang Tao , Xingbin Zhao , Pinwen Zhu , Tian Cui","doi":"10.1016/j.isci.2025.112803","DOIUrl":"10.1016/j.isci.2025.112803","url":null,"abstract":"<div><div>Transition metal borides are important superhard multifunctional materials, in which boron concentration predetermined crystal and properties. However, the principles for effectively controlling properties through boron concentration remain unclear. Here, we reported the evolution of crystal structure, hardness, and magnetic behavior with boron concentration. Boron atoms tend to form isolated boron, boron chains, boron nets, and three-dimensional boron frameworks as boron concentration rises. The Vickers hardness initially increases from Mn<sub>2</sub>B to Mn<sub>3</sub>B<sub>4</sub>, then drops at MnB<sub>2</sub>, and finally reaches the highest value for MnB<sub>4</sub>, which suggest higher boron concentration is not a necessary factor for higher hardness, and the motifs of boron backbone are equally crucial. Moreover, boron sub-structure act as mediators of long-range ferromagnetic interactions, as evidenced by the evolution of magnetic behavior from paramagnetic, ferromagnetic, antiferromagnetic, and then paramagnetic behavior. These findings underscore the importance of manipulating boron backbone motifs to achieve high harness and superior magnetic properties.</div></div>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 7","pages":"Article 112803"},"PeriodicalIF":4.6,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144366178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0