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Catecholamine-Secreting Retroperitoneal Paraganglioma: A Case Report and Literature Review. 儿茶酚胺分泌腹膜后副神经节瘤1例报告及文献复习。
Case Reports in Urology Pub Date : 2026-10-11 eCollection Date: 2026-01-01 DOI: 10.1155/criu/2760597
Eduardo Felício, Nuno Gião, Guilherme Bernardo, André Barcelos, Sara Duarte, Filipe Gaboleiro, André Pita, Diogo Carmali, Diogo Saraiva, Catarina Roque, João Varregoso, Fernando Ferrito
{"title":"Catecholamine-Secreting Retroperitoneal Paraganglioma: A Case Report and Literature Review.","authors":"Eduardo Felício, Nuno Gião, Guilherme Bernardo, André Barcelos, Sara Duarte, Filipe Gaboleiro, André Pita, Diogo Carmali, Diogo Saraiva, Catarina Roque, João Varregoso, Fernando Ferrito","doi":"10.1155/criu/2760597","DOIUrl":"10.1155/criu/2760597","url":null,"abstract":"<p><strong>Introduction: </strong>Paragangliomas are rare neuroendocrine tumors arising from autonomic paraganglia. These tumors have metastatic potential, and histopathological findings alone cannot reliably predict their biological behavior. Clinical manifestations range from the classic triad of headache, diaphoresis, and palpitations to incidental findings in asymptomatic patients.</p><p><strong>Case presentation: </strong>A 75-year-old man was incidentally found to have a 5 cm retroperitoneal mass adjacent to the right renal hilum. Biochemical testing confirmed marked catecholamine hypersecretion, and 18F-FDOPA PET/CT demonstrated isolated uptake within the lesion without additional disease. Preoperative preparation included progressive alpha-adrenergic blockade with doxazosin for approximately 1 month, followed by atenolol for heart rate control. An open approach through a right subcostal hemichevron incision was selected because the tumor was located between the right renal artery and vein and lateral to the inferior vena cava. During dissection, an iatrogenic renal artery injury with intraoperative hemorrhage occurred, necessitating en bloc removal of the tumor, right kidney, and right adrenal gland. Histopathological examination confirmed a paraganglioma with a Ki-67 proliferation index below 1%, focal nuclear atypia, no mitotic figures, no tumor necrosis, no vascular invasion, and microscopic margin involvement. Immunohistochemistry was positive for Chromogranin A, synaptophysin, GATA-3, and S100. Germline testing using a 14-gene pheochromocytoma-paraganglioma panel identified no reported pathogenic or likely pathogenic variants. At 6 months, contrast-enhanced thoracoabdominopelvic computed tomography showed no evidence of local recurrence or metastatic disease, and plasma and urinary metanephrines had normalized, consistent with postoperative biochemical remission. The patient remains under joint endocrinology and urology follow-up with lifelong annual clinical and biochemical surveillance.</p><p><strong>Discussion and conclusion: </strong>This case highlights the diagnostic and surgical challenges of a functioning perihilar retroperitoneal paraganglioma. Careful endocrine preparation, vascular planning, multidisciplinary management, and lifelong surveillance are essential, particularly when the surgical margin is microscopically involved.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"2760597"},"PeriodicalIF":0.0,"publicationDate":"2026-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous Pregnancy After Surgical Correction of a Prostatic Utricle Cyst and Recurrent Varicocele: A Case Report. 前列腺小囊囊肿及精索静脉曲张术后自然妊娠一例报告。
Case Reports in Urology Pub Date : 2026-10-08 eCollection Date: 2026-01-01 DOI: 10.1155/criu/5477079
Caio Bosquê Hidalgo Ribeiro, Luiz Felipe Lessa Ortiz, Júlia Ribeiro Rezende, Bárbara Bomfim Muniz Moraes, Henrique Cunha Vieira, Amanda Lino De Faria Lessa
{"title":"Spontaneous Pregnancy After Surgical Correction of a Prostatic Utricle Cyst and Recurrent Varicocele: A Case Report.","authors":"Caio Bosquê Hidalgo Ribeiro, Luiz Felipe Lessa Ortiz, Júlia Ribeiro Rezende, Bárbara Bomfim Muniz Moraes, Henrique Cunha Vieira, Amanda Lino De Faria Lessa","doi":"10.1155/criu/5477079","DOIUrl":"https://doi.org/10.1155/criu/5477079","url":null,"abstract":"<p><strong>Background: </strong>Prostatic utricle cysts are rare congenital anomalies arising from incomplete regression of the Müllerian ducts that may cause partial or complete ejaculatory duct obstruction, leading to hypospermia, abnormal semen parameters and even azoospermia in severe cases. Recurrent varicocele after previous surgical repair represents an additional challenge in the management of male infertility. Here, we report a case of spontaneous pregnancy achieved after combined surgical correction of a prostatic utricle cyst and recurrent left-sided varicocele in a couple not yet meeting the formal 12-month criteria for infertility, illustrating the diagnostic and therapeutic considerations relevant to this clinical scenario.</p><p><strong>Case presentation: </strong>A 27-year-old man with a history of bilateral microsurgical varicocelectomy in 2018, persistent hypospermia (ejaculate volume 0.1-0.5 mL), reduced sperm motility (8%-24% progressive motility) and abnormal strict Kruger morphology (1%-3%) was evaluated together with his 35-year-old partner after 6 months of attempting natural conception. Scrotal Doppler ultrasonography confirmed recurrent left-sided varicocele, and pelvic magnetic resonance imaging revealed a prostatic utricle cyst measuring 1.6 × 1.0 cm. The female partner had no relevant abnormalities on complete gynaecological evaluation. The male partner underwent transurethral resection of the prostatic utricle cyst combined with subinguinal microsurgical redo varicocelectomy in a single surgical session without complications. Two months postoperatively, spontaneous clinical pregnancy was confirmed, and two semen analyses performed 4 months after surgery showed normalisation of all seminal parameters.</p><p><strong>Conclusions: </strong>This case highlights the importance of comprehensive andrological evaluation, including imaging studies, in couples with a pre-existing, known male-factor abnormality, even when formal infertility criteria are not yet met. Prostatic utricle cysts should be considered in the differential diagnosis of obstructive male infertility, particularly in patients with unexplained hypospermia. In this case, combined correction of coexisting reproductive tract abnormalities was followed by normalisation of postoperative semen parameters and a favourable reproductive outcome; because semen analysis was performed only after conception had already occurred, a causal relationship with the pregnancy itself cannot be definitively established, but the findings support a positive physiological effect of surgery. Surgical reintervention for recurrent varicocele remains justified in selected patients with persistently abnormal semen parameters.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"5477079"},"PeriodicalIF":0.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13650253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Open Cystolithotomy Under Local Anesthesia in a High-Risk Patient With a Giant Bladder Stone and Unilateral Lung Collapse: A Case Report. 局部麻醉下开放性膀胱取石术治疗高危膀胱结石伴单侧肺塌陷1例。
Case Reports in Urology Pub Date : 2026-10-06 eCollection Date: 2026-01-01 DOI: 10.1155/criu/9312974
Milan Gyawali, Ritamvara Oli, Sunil Regmi, Purushottam Parajuli, Akash Chitrakar, Rabindra Tamang
{"title":"Open Cystolithotomy Under Local Anesthesia in a High-Risk Patient With a Giant Bladder Stone and Unilateral Lung Collapse: A Case Report.","authors":"Milan Gyawali, Ritamvara Oli, Sunil Regmi, Purushottam Parajuli, Akash Chitrakar, Rabindra Tamang","doi":"10.1155/criu/9312974","DOIUrl":"10.1155/criu/9312974","url":null,"abstract":"<p><strong>Introduction: </strong>Giant bladder stone is rare in current scenarios. When patients also have severe pulmonary disease, anesthesia becomes high risk. This case illustrates how open cystolithotomy under local anesthesia can be a viable option in such medically compromised patients.</p><p><strong>Case presentation: </strong>A 60-year-old male from rural Eastern Nepal presented after prolonged history of lower urinary tract symptoms, hematuria, and progressive shortness of breath. Chest imaging revealed a collapsed left lung. Abdominal imaging showed a giant bladder stone (11 <sup>∗</sup>8 cm). Given the patient's severely reduced pulmonary reserve, he underwent open cystolithotomy under local anesthesia with mild sedation. The stone was removed successfully with no major perioperative complications.</p><p><strong>Discussion: </strong>In patients with a collapsed left lung, the anesthetic risk associated with general or spinal anesthesia is significantly high. In such circumstances, local anesthesia with sedation, although uncommon for open bladder surgery, may be considered when the patient's clinical condition mandates it. Adequate preoperative optimization, including chest physiotherapy and careful perioperative monitoring, is essential. Management requires balancing the risks of anesthesia against the risks of leaving the stone untreated, such as infection, renal damage, and bladder dysfunction.</p><p><strong>Conclusion: </strong>Open cystolithotomy under local anesthesia with mild sedation may be a feasible alternative in high-risk cases with giant bladder stone where general/regional anesthesia is contraindicated. Early detection, multidisciplinary management, and resource allocation are essential especially in rural and under-resourced regions for prevention and management of these cases.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"9312974"},"PeriodicalIF":0.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Voluminous Seminal Vesicle Cyst Treated by Laparoscopic-Guided Alcoholization: A Case Report and Review of the Literature. 腹腔镜引导下酒精化治疗大体积精囊囊肿1例报告及文献复习。
Case Reports in Urology Pub Date : 2026-10-05 eCollection Date: 2026-01-01 DOI: 10.1155/criu/8835546
Giuseppe Pizzuto, Paolo Massenio, Vincenzo Stellacci, Francesco Lafranceschina, Salvatore Giordano, Felice Arborea, Fabio Ambruoso, Andrea Capurso, Mario De Siati
{"title":"Voluminous Seminal Vesicle Cyst Treated by Laparoscopic-Guided Alcoholization: A Case Report and Review of the Literature.","authors":"Giuseppe Pizzuto, Paolo Massenio, Vincenzo Stellacci, Francesco Lafranceschina, Salvatore Giordano, Felice Arborea, Fabio Ambruoso, Andrea Capurso, Mario De Siati","doi":"10.1155/criu/8835546","DOIUrl":"10.1155/criu/8835546","url":null,"abstract":"<p><p>Seminal vesicle cysts are uncommon anomalies of the male genitourinary tract and are often discovered incidentally. When large, they may become symptomatic, causing lower urinary tract symptoms and hematospermia. Surgical excision is generally recommended for symptomatic cases, although this approach may be associated with nonnegligible morbidity. We report the case of a large seminal vesicle cyst associated with ipsilateral renal agenesis, successfully treated with laparoscopic-guided aspiration and alcohol sclerotherapy. To our knowledge, this technique has not previously been described. The procedure resulted in symptom resolution and radiological disappearance of the cyst at short-term follow-up.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"8835546"},"PeriodicalIF":0.0,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13639383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic Heterogeneity in Renal Cell Carcinoma: A Case of Concurrent Clear Cell and Papillary Renal Carcinomas. 肾细胞癌的遗传异质性:一例透明细胞癌和乳头状肾癌同时发生。
Case Reports in Urology Pub Date : 2026-10-02 eCollection Date: 2026-01-01 DOI: 10.1155/criu/5538985
Annelies Kerckhofs, Stéphanie Dautricourt, Léon van Kempen, Stefan De Wachter, Ali Ramadhan
{"title":"Genetic Heterogeneity in Renal Cell Carcinoma: A Case of Concurrent Clear Cell and Papillary Renal Carcinomas.","authors":"Annelies Kerckhofs, Stéphanie Dautricourt, Léon van Kempen, Stefan De Wachter, Ali Ramadhan","doi":"10.1155/criu/5538985","DOIUrl":"https://doi.org/10.1155/criu/5538985","url":null,"abstract":"<p><strong>Background/objectives: </strong>Recent advancements in genetic research have significantly enhanced the understanding of renal cell carcinoma (RCC), now recognized as a heterogeneous group with distinct genetic features. This case report is aimed at illustrating its genetic diversity and implications for diagnosis and treatment.</p><p><strong>Methods: </strong>A middle-aged man presented with an incidental finding of RCC in the right kidney on computer tomography (CT) performed for a persistent cough. Comprehensive radiological and blood tests were conducted, followed by a total right nephrectomy. Histological examination showed a concurrent appearance of two manifestly different tumors in the kidney. Molecular analyses, including SNP array and next-generation sequencing (NGS), were conducted to identify genetic mutations and assess clonality.</p><p><strong>Results: </strong>The nephrectomy identified two distinct tumors: a clear cell RCC (ISUP/WHO grade 3, pT1b) and a papillary RCC (ISUP/WHO grade 2, pT1a). Molecular analysis confirmed <i>VHL</i>, <i>TP53</i>, and <i>SETD2</i> mutations in the clear cell RCC, whereas no mutations were detected in the papillary RCC. The SNP array revealed significant chromosomal differences, suggesting the tumors were not clonally related. Follow-up imaging detected an adrenal metastasis from the clear cell RCC. The metastasis showed a <i>VHL</i> and <i>SETD2</i> mutation, which undoubtedly proved to be derived from the clear cell RCC.</p><p><strong>Conclusions: </strong>This case underscores the genetic heterogeneity of RCC and the importance of molecular profiling in guiding diagnosis and treatment. The distinct genetic profiles of the two tumors suggest they are not clonally related, highlighting the complexity of RCC and the need for individualized therapeutic approaches.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"5538985"},"PeriodicalIF":0.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13633462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149115622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent Left Ureterosciatic Herniation With Obstructive Hydronephrosis: A Case Report. 复发性左输尿管疝伴梗阻性肾积水1例。
Case Reports in Urology Pub Date : 2026-09-25 eCollection Date: 2026-01-01 DOI: 10.1155/criu/1012541
Venkatesh Perumalla, Thomas Neerhut, Eve Brown, John Blazak, Chandra Perumalla, Abigail Attwell-Heap
{"title":"Recurrent Left Ureterosciatic Herniation With Obstructive Hydronephrosis: A Case Report.","authors":"Venkatesh Perumalla, Thomas Neerhut, Eve Brown, John Blazak, Chandra Perumalla, Abigail Attwell-Heap","doi":"10.1155/criu/1012541","DOIUrl":"10.1155/criu/1012541","url":null,"abstract":"<p><p>Uretero-sciatic herniation is an exceptionally rare cause of ureteric obstruction, resulting from herniation of the ureter via the sciatic foramen. A 66-year-old woman presented with left flank pain and deteriorating renal function. Computed tomography intravenous pyelogram (CT IVP) demonstrated severe left hydronephrosis secondary to herniation of the ureter through the left sciatic foramen. The patient then underwent successful renal decompression with an endoscopic retrograde ureteric stent placed. Subsequent trial of stent removal failed, with left uretero-sciatic herniation and renal obstruction recurring shortly after stent removal. Multidisciplinary review led to further evaluation for potential underlying pathology and subsequent definitive open ureterolysis, ureteric reduction and omental wrapping being performed. This case report highlights the pertinent clinical, radiological and management principles underlying such rare pathology. The possible association of piriformal atrophy as an underlying precipitant is discussed along with the key radiological findings of such rare pathology. Within the literature, evidence-based definitive management options are limited and currently require multidisciplinary discussion with invasive surgical correction to be considered following failure of more minimally invasive endoscopic management. In this case, given the success of open ureterolysis and omental wrapping, it is hoped future cases may benefit from this knowledge and consider similar surgical approaches to achieve definitive management.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"1012541"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13613437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149064804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cystinuria Diagnosed at Age 67 Following a 49-Year Diagnostic Delay: A Reminder of Indolent Cystinuria in Adult Urolithiasis-A Case Report. 延迟49年诊断后67岁诊断为胱氨酸尿症:提示成人尿石症患者存在惰性胱氨酸尿症——一例报告。
Case Reports in Urology Pub Date : 2026-09-19 eCollection Date: 2026-01-01 DOI: 10.1155/criu/8475574
Sarah Jeffery, Matthew Tyson, Laura McAuley, John Harty
{"title":"Cystinuria Diagnosed at Age 67 Following a 49-Year Diagnostic Delay: A Reminder of Indolent Cystinuria in Adult Urolithiasis-A Case Report.","authors":"Sarah Jeffery, Matthew Tyson, Laura McAuley, John Harty","doi":"10.1155/criu/8475574","DOIUrl":"10.1155/criu/8475574","url":null,"abstract":"<p><p>Cystinuria is a genetic disorder resulting from mutations in the SLC3A1 and SLC7A9 genes, which impair the reabsorption of cystine, ornithine, lysine and arginine and lead to increased urinary excretion of cystine. Elevated urinary cystine concentration promotes precipitation and subsequent stone formation, manifesting as recurrent urolithiasis. Cystinuria is the most common genetic condition that results in urolithiasis and is typically diagnosed in adolescence. In this case report, we present a male patient diagnosed with cystinuria at the age of 67. The patient presented with acute left flank pain, and noncontrast CT imaging of the urinary tract identified left renal calculi and multiple proximal ureteric stones, accompanied by hydronephrosis. Ureteroscopy revealed dense calculi resistant to laser fragmentation, and stone analysis confirmed a 100% cystine composition. The patient reported a previous stone event at age 18 with spontaneous passage but had remained stone-free for nearly 50 years and had no prior diagnosis of cystinuria. This case demonstrates that cystinuria, although typically diagnosed in childhood or adolescence, can be diagnosed in older adults with recurrent or resistant urolithiasis. Clinicians should maintain a high index of suspicion for cystinuria in adult patients with unexplained or refractory stone disease, and stone analysis remains essential for accurate diagnosis. Optimal management centres on preventing recurrent stone formation through aggressive fluid intake, dietary modifications and medical alkalinisation of urine. Multidisciplinary follow-up is important to reduce the risk of renal impairment and potential later need for nephrectomy.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"8475574"},"PeriodicalIF":0.0,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13589192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phosphodiesterase-5 Inhibitor Use Masking a Necrotizing Syphilitic Infection: A Rare Differential Diagnosis of Priapism. 磷酸二酯酶-5抑制剂的使用掩盖了坏死性梅毒感染:一种罕见的阴茎勃起症鉴别诊断。
Case Reports in Urology Pub Date : 2026-09-17 eCollection Date: 2026-01-01 DOI: 10.1155/criu/6685174
Dimitrios M Papadimopoulos, Apostolos Chasapis, Konstantinos Sitaridis, Evangelos Arapis, Nikolaos Kalogeras, Apostolos Papalakis
{"title":"Phosphodiesterase-5 Inhibitor Use Masking a Necrotizing Syphilitic Infection: A Rare Differential Diagnosis of Priapism.","authors":"Dimitrios M Papadimopoulos, Apostolos Chasapis, Konstantinos Sitaridis, Evangelos Arapis, Nikolaos Kalogeras, Apostolos Papalakis","doi":"10.1155/criu/6685174","DOIUrl":"10.1155/criu/6685174","url":null,"abstract":"<p><strong>Background: </strong>Acute penile enlargement is often presumed to indicate priapism, particularly after Phosphodiesterase-5 inhibitor use. However, alternative diagnoses, including infectious and necrotizing processes, should be considered-especially in patients with a history of unprotected sex-to avoid delayed or inappropriate management.</p><p><strong>Case presentation: </strong>A 43-year-old male with a history of intravenous drug use presented with acute penile swelling and leukocytosis (20,500/<i>μ</i>L) following unprotected sexual intercourse and tadalafil consumption. Although priapism was suspected, corporal blood gas analysis demonstrated oxygenation and pH levels that excluded ischemic priapism. The patient was admitted to the clinic, and empiric intravenous antibiotics (piperacillin/tazobactam and clindamycin) were initiated. Despite laboratory improvement, penile edema and erythema progressed with early necrotic changes. Postoperative history obtained from a relative revealed prior inadequately treated syphilis, subsequently confirmed by serologic testing. <i>Τ</i>he patient underwent surgical debridement of necrotic tissue surrounding the corporal bodies. He was discharged and referred to a specialized center for syphilis treatment. The patient recovered without further complications and demonstrated preserved erectile function at 1-month follow-up.</p><p><strong>Conclusion: </strong>Acute penile enlargement following Phosphodiesterase-5 inhibitor use is not necessarily attributable to priapism and may instead be caused by infectious or necrotizing etiologies. Prompt recognition, initiation of antimicrobial therapy, and timely surgical intervention are critical to preserve penile tissue and erectile function.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"6685174"},"PeriodicalIF":0.0,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative Ultrasound-Guided Repair of Penile Fracture: A Case Report. 术中超声引导下阴茎骨折修复1例。
Case Reports in Urology Pub Date : 2026-09-08 eCollection Date: 2026-01-01 DOI: 10.1155/criu/3418235
Hoi-Lung Wong, Omar Wai-Kiu Tsui, Brian Sze-Ho Ho, Ada Tsui-Lin Ng
{"title":"Intraoperative Ultrasound-Guided Repair of Penile Fracture: A Case Report.","authors":"Hoi-Lung Wong, Omar Wai-Kiu Tsui, Brian Sze-Ho Ho, Ada Tsui-Lin Ng","doi":"10.1155/criu/3418235","DOIUrl":"10.1155/criu/3418235","url":null,"abstract":"<p><p>Penile fracture is a rare urological emergency resulting from rupture of the tunica albuginea during blunt trauma to an erect penis, typically during sexual intercourse. While immediate surgical repair is associated with superior outcomes compared with conservative management, delayed treatment can lead to significant long-term complications including penile curvature in 30% of cases and erectile dysfunction in 50%-62% of cases. We present the case of a 22-year-old patient who sustained a penile fracture while manipulating his erect penis. Clinical examination revealed penile swelling, bruising, and a 60° leftward curvature. Intraoperative ultrasound (IO-USG) with a linear probe precisely localized a tunica albuginea defect in the right corpus cavernosum, enabling a minimally invasive 1.5-cm transverse incision directly over the fracture site. This approach avoided complete penile degloving, reduced operative time and blood loss, and facilitated complete clot evacuation and defect closure using interrupted 3-0 PDS sutures. Postoperative recovery was uneventful, with the patient discharged the following day and reporting normal erectile function and no penile deformity at the 3-month follow-up. A literature review confirms that while preoperative imaging is commonly utilized for surgical planning, IO-USG guidance for real-time fracture localization and incision placement remains rarely reported. Although MRI and CT offer superior soft tissue resolution, they are limited by availability, time constraints, and radiation exposure. IO-USG is readily accessible and noninvasive; although operator-dependent, it provides high-resolution real-time guidance that enables smaller incisions, minimizes postoperative complications such as glans numbness, and optimizes functional outcomes. We conclude that IO-USG-guided repair of penile fracture facilitates rapid identification of the injury site, accurate assessment of hematoma burden, and targeted surgical approach that avoids penile degloving while ensuring complete repair.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"3418235"},"PeriodicalIF":0.0,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13551490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Worm-Like Illusion: Fibrin Clot Mimicking Parasitic Infection in a Child With Hematuria. 蠕虫样错觉:血尿患儿纤维蛋白凝块模拟寄生虫感染。
Case Reports in Urology Pub Date : 2026-09-03 eCollection Date: 2026-01-01 DOI: 10.1155/criu/9561616
Ali Sweidat, Yaser El Hout, Abderrahman El Kadhi
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