Late-Onset Penile Fracture After Collagenase Clostridium histolyticum Treatment for Peyronie's Disease in a 70-Year-Old Patient.

Case Reports in Urology Pub Date : 2025-09-02 eCollection Date: 2025-01-01 DOI:10.1155/criu/2126627
Matthew D Wainstein, Sonia E Masih, Timothy G Schuster
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引用次数: 0

Abstract

Collagenase Clostridium histolyticum (CCH) injections are the gold standard for nonsurgical management of Peyronie's disease. While generally well tolerated, penis fracture is a known complication. Cases typically occur during intercourse in the weeks following treatment. Because of this, patients are advised to abstain from sexual activity for 4 weeks postinjection. Here, we present a case of corporal rupture occurring 32 days after treatment. This is only the third reported case occurring 30 days after injection. While the risk of penis fracture likely decreases with time, these cases illustrate that the risk may extend beyond 4 weeks.

胶原酶溶组织梭菌后迟发性阴茎骨折治疗一例70岁佩罗尼病患者。
胶原酶溶组织梭菌(CCH)注射是Peyronie病非手术治疗的金标准。阴茎骨折是一种已知的并发症,但通常耐受性良好。病例通常发生在治疗后几周的性交期间。因此,建议患者在注射后4周内不要进行性活动。在这里,我们提出了一个病例下体破裂发生32天后治疗。这是在注射后30天发生的第三例报告病例。虽然阴茎骨折的风险可能会随着时间的推移而降低,但这些病例表明,风险可能会超过4周。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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审稿时长
13 weeks
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