Matthew D Wainstein, Sonia E Masih, Timothy G Schuster
{"title":"胶原酶溶组织梭菌后迟发性阴茎骨折治疗一例70岁佩罗尼病患者。","authors":"Matthew D Wainstein, Sonia E Masih, Timothy G Schuster","doi":"10.1155/criu/2126627","DOIUrl":null,"url":null,"abstract":"<p><p>Collagenase <i>Clostridium histolyticum</i> (CCH) injections are the gold standard for nonsurgical management of Peyronie's disease. While generally well tolerated, penis fracture is a known complication. Cases typically occur during intercourse in the weeks following treatment. Because of this, patients are advised to abstain from sexual activity for 4 weeks postinjection. Here, we present a case of corporal rupture occurring 32 days after treatment. This is only the third reported case occurring 30 days after injection. While the risk of penis fracture likely decreases with time, these cases illustrate that the risk may extend beyond 4 weeks.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2025 ","pages":"2126627"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419919/pdf/","citationCount":"0","resultStr":"{\"title\":\"Late-Onset Penile Fracture After Collagenase <i>Clostridium histolyticum</i> Treatment for Peyronie's Disease in a 70-Year-Old Patient.\",\"authors\":\"Matthew D Wainstein, Sonia E Masih, Timothy G Schuster\",\"doi\":\"10.1155/criu/2126627\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Collagenase <i>Clostridium histolyticum</i> (CCH) injections are the gold standard for nonsurgical management of Peyronie's disease. While generally well tolerated, penis fracture is a known complication. Cases typically occur during intercourse in the weeks following treatment. Because of this, patients are advised to abstain from sexual activity for 4 weeks postinjection. Here, we present a case of corporal rupture occurring 32 days after treatment. This is only the third reported case occurring 30 days after injection. While the risk of penis fracture likely decreases with time, these cases illustrate that the risk may extend beyond 4 weeks.</p>\",\"PeriodicalId\":30323,\"journal\":{\"name\":\"Case Reports in Urology\",\"volume\":\"2025 \",\"pages\":\"2126627\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-09-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419919/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Urology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/criu/2126627\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Urology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/criu/2126627","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Late-Onset Penile Fracture After Collagenase Clostridium histolyticum Treatment for Peyronie's Disease in a 70-Year-Old Patient.
Collagenase Clostridium histolyticum (CCH) injections are the gold standard for nonsurgical management of Peyronie's disease. While generally well tolerated, penis fracture is a known complication. Cases typically occur during intercourse in the weeks following treatment. Because of this, patients are advised to abstain from sexual activity for 4 weeks postinjection. Here, we present a case of corporal rupture occurring 32 days after treatment. This is only the third reported case occurring 30 days after injection. While the risk of penis fracture likely decreases with time, these cases illustrate that the risk may extend beyond 4 weeks.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
