Surgical Case Reports最新文献

{"title":"A Case Report of Severe Thrombocytopenic Purpura during Neoadjuvant Pembrolizumab Administration for Triple-Negative Breast Cancer.","authors":"Ryoko Semba, Shiori Tohyama, Yumiko Ushiyama, Fumi Murakami, Sakiko Harada, Kanako Ogura, Junichiro Watanabe","doi":"10.70352/scrj.cr.24-0036","DOIUrl":"10.70352/scrj.cr.24-0036","url":null,"abstract":"<p><strong>Introduction: </strong>Immune thrombocytopenic purpura (ITP) is one of the immune-related adverse events (irAEs) related to immune checkpoint inhibitors (ICIs). Here, we report a case of a 51-year-old woman with triple-negative breast cancer (TNBC) who experienced severe thrombocytopenic purpura during the neoadjuvant chemotherapy (NAC), including pembrolizumab.</p><p><strong>Case presentation: </strong>A 51-year-old woman was diagnosed with Stage II B TNBC and underwent NAC using pembrolizumab + paclitaxel + carboplatin. Her blood test on cycle 4, day 15 (C4D15) showed a significant decrease in platelets to <2000/μL accompanied by overt bleeding tendency. She was hospitalized for further investigation and treatment. Her platelet count recovered after platelet concentrate transfusion and corticosteroid administration. Her bone marrow examination showed normal cellularity, and she was judged as ITP. Due to the event and good clinical response to NAC, she underwent a right partial mastectomy and axillary lymph node dissection without completion of the planned NAC. The surgical specimen showed a complete pathological response.</p><p><strong>Conclusions: </strong>Thrombocytopenia is known as one of the hematologic irAEs; however, severe thrombocytopenia with a bleeding tendency is rarely reported. Sufficient explanations to patients and appropriate referral to other related departments are important for earlier detection and treatment of irAE.</p>","PeriodicalId":22096,"journal":{"name":"Surgical Case Reports","volume":"11 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrahepatic Cholangiocarcinoma with <i>BRCA</i> Mutation Achieved Pathological Complete Response after Neoadjuvant Gemcitabine, Cisplatin, and S-1 Therapy: A Case Report.","authors":"Yoshifumi Morita, Koki Oda, Akio Matsumoto, Shinya Ida, Ryo Kitajima, Satoru Furuhashi, Makoto Takeda, Hirotoshi Kikuchi, Yoshihiro Hiramatsu, Jun Ito, Takeshi Chida, Hidenao Noritake, Kazuhito Kawata, Yuka Nagakura, Mana Goto, Satoshi Baba, Hiroya Takeuchi","doi":"10.70352/scrj.cr.24-0042","DOIUrl":"10.70352/scrj.cr.24-0042","url":null,"abstract":"<p><strong>Introduction: </strong>Intrahepatic cholangiocarcinoma (ICC) is a highly malignant cancer for which surgery is the only curative treatment. The prognosis of ICC is extremely poor, especially in cases of lymph node metastasis (LNM), owing to the high postoperative recurrence rate. Herein, we present a case of advanced ICC with a breast cancer susceptibility gene-2 (<i>BRCA2</i>) mutation, treated with preoperative chemotherapy, including cisplatin, followed by surgery, in which we achieved a pathologic complete response.</p><p><strong>Case presentation: </strong>A 52-year-old woman was referred to our hospital and was subsequently diagnosed with bilateral breast cancer. Computed tomography (CT) and magnetic resonance imaging incidentally detected a liver tumor in the hilar region and lymph node enlargement in the hepatoduodenal ligament. A 19 mm tumor was observed in the area surrounded by the right and left branches of the portal vein and an abnormal portal branch of segment 7. Positron emission tomography-CT showed fluorodeoxyglucose uptake in the liver tumor, hepatoduodenal ligament lymph nodes, and bilateral breasts. A tumor biopsy showed a papillary tumor, and ICC was suspected. As ICC with LNM has a poor prognosis, neoadjuvant chemotherapy was planned. Genetic testing using a blood sample revealed a <i>BRCA2</i> mutation, indicating the patient would benefit from chemotherapy, particularly cisplatin. The patient received a chemotherapy regimen comprised of gemcitabine, cisplatin, and S-1 (GCS), and after 7 courses, her carbohydrate antigen 19-9 level decreased from 2433 to 15 U/mL. CT showed that the tumor had shrunk and the LNMs were indistinct. The patient was referred to our department for curative surgery, which included a left hepatectomy, caudate lobectomy, hepatoduodenal ligament lymph node dissection, bile duct resection, and choledocojejunostomy. The postoperative course was generally uneventful, and the patient was discharged on postoperative day 18. Pathological examination of the resected specimen revealed an absence of malignant cells. At 24 months postoperative, there was no evidence of recurrence.</p><p><strong>Conclusions: </strong>We encountered a patient with advanced ICC with a <i>BRCA2</i> mutation, which was successfully treated with preoperative GCS therapy followed by surgical resection, and a pathologic complete response was achieved. GCS therapy, therefore, appears promising as neoadjuvant chemotherapy for the treatment of ICC.</p>","PeriodicalId":22096,"journal":{"name":"Surgical Case Reports","volume":"11 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Right Upper Lung Segmentectomy after Esophagectomy: Utilization of 4K 3-Dimensional Endoscopy and Near-Infrared Fluorescence in High-Risk Surgery.","authors":"Masaya Otabe, Sayaka Yamada, Atsushi Kagimoto, Takeshi Mimura","doi":"10.70352/scrj.cr.24-0144","DOIUrl":"10.70352/scrj.cr.24-0144","url":null,"abstract":"<p><strong>Introduction: </strong>Lung resection after open esophagectomy poses significant technical challenges, particularly when the reconstructed gastrointestinal tract is on the same side as the lung lesion. The advent of 4K 3-dimensional (3D) endoscopic systems with near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) has improved the precision of thoracic surgeries. We present a case of successful right upper lung segmentectomy for primary lung cancer after open esophagectomy, utilizing a 4K 3D endoscopic system and NIR imaging.</p><p><strong>Case presentation: </strong>An 85-year-old female with a history of open esophagectomy for esophageal cancer 19 years earlier and comorbidities, including aplastic anemia and diabetes mellitus, was referred for the evaluation of a growing lesion in the right upper lung. Computed tomography (CT) revealed a 43-mm tumor and the gastric tube, reconstructed during the prior esophagectomy, located in the right thoracic cavity. A CT-guided biopsy confirmed lung adenocarcinoma (cT2bN0M0, Stage IIA). Surgical challenges included severe adhesions from the previous thoracotomy and thrombocytopenia (platelet count: 20000) due to aplastic anemia. A thoracoscopic segmentectomy of the anterior segment of the right upper lobe was performed using a 4K 3D endoscopic system (TIPCAM1 Rubina; Karl Storz, Tuttlingen, Germany). Adhesions were meticulously dissected, and intraoperative platelet transfusions were administered. NIR imaging with ICG identified the intersegmental plane and confirmed blood flow to the gastric tube, preventing ischemic complications. The lung segmentectomy was completed using staplers, preserving the right gastroepiploic artery. Histopathology revealed acinar adenocarcinoma (pT3N0M0, Stage IIB). The patient resumed oral intake on postoperative Day 1 and was discharged on Day 13 without complications. No recurrence was noted during the follow-up.</p><p><strong>Conclusions: </strong>This case demonstrates the effective use of 4K 3D endoscopic systems and NIR imaging with ICG in complex lung resections following open esophagectomy. These technologies facilitate precise dissection and blood flow assessment, which are crucial for preserving reconstructed structures and enhancing surgical safety.</p>","PeriodicalId":22096,"journal":{"name":"Surgical Case Reports","volume":"11 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11836011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Regression of Advanced Transverse Colon Cancer: A Case Report.","authors":"Shinya Ohno, Yoshinori Iwata, Saki Mitsutome, Shusaku Kawai, Manabu Neo, Moe Fukuda, Bei Wang, Tomonari Suetsugu, Taku Watanabe, Shuji Komori, Chihiro Tanaka, Narutoshi Nagao, Masahiko Kawai","doi":"10.70352/scrj.cr.24-0018","DOIUrl":"10.70352/scrj.cr.24-0018","url":null,"abstract":"<p><strong>Introduction: </strong>The incidence of spontaneous regression (SR) of malignancy is one in 60000-100000 cancer patients and spontaneous regression in colorectal cancer is quite rare, reported to account for less than 2% of spontaneous regression of malignancy. In recent years, some reports of spontaneous regression in colorectal cancer in patients with high-frequency microsatellite instability have suggested a deep association between high-frequency microsatellite instability and spontaneous regression. We report our experience of spontaneous regression of advanced colorectal cancer with high-frequency microsatellite instability and provide a review of spontaneous regression in colorectal cancer.</p><p><strong>Case presentation: </strong>An 83-year-old woman was diagnosed as having advanced colorectal cancer in the transverse colon by lower gastrointestinal endoscopy, and biopsy results revealed moderately differentiated adenocarcinoma. Contrast-enhanced computed tomography showed a tumor located near the hepatic flexure and an enlarged lymph node near the tumor. No distant metastasis was observed, and the preoperative diagnosis was cT3N1aM0 cStage IIIb cancer. Immunohistochemical analysis of the biopsy specimen suggested deficient mismatch repair. During the wait for surgery, the patient was urgently hospitalized due to severe dehydration. After her general condition improved, 38 days after the biopsy, we performed laparoscopic resection of the partial ascending and transverse colon with D3 lymph node dissection. The tumor noted preoperatively was not present in the specimen, and intraoperative endoscopy revealed no tumor on the anorectal side. Additional ileocecal resection was performed, but no tumor was found in the specimen, and another intraoperative endoscopy was performed, which revealed a discolored scar near the anal margin. We determined that tumor loss or morphological change had occurred, so after additional resection of the same area, ultimately, an extended right hemicolectomy was performed. Histopathological diagnosis was pT0N0M0 pStage0 cancer with no residual tumor. The patient has progressed without recurrence at 1 year after the operation.</p><p><strong>Conclusions: </strong>The immunological response due to high-frequency microsatellite instability may be related to the mechanism of spontaneous regression in colorectal cancer. If high-frequency microsatellite instability is diagnosed preoperatively, we recommend that the tumor location should be confirmed preoperatively.</p>","PeriodicalId":22096,"journal":{"name":"Surgical Case Reports","volume":"11 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robot-Assisted Ultra-Low Anterior Resection for Rectal Neuroendocrine Tumors after Severe Perineal Tears: A Case Report.","authors":"Kenji Baba, Masumi Wada, Naoki Kuroshima, Yuto Hozaka, Daisaku Kamiimabeppu, Masataka Shimonosono, Yota Kawasaki, Ken Sasaki, Michiyo Higashi, Hiroaki Kobayashi, Takaaki Arigami, Takao Ohtsuka","doi":"10.70352/scrj.cr.24-0012","DOIUrl":"10.70352/scrj.cr.24-0012","url":null,"abstract":"<p><strong>Introduction: </strong>Surgical repair of severe perineal tears is required immediately postpartum. Owing to their low prevalence, the post-treatment course of severe tears is not well known. Herein, we report a rare case of a young woman who underwent robot-assisted curative resection with anal preservation for a rectal neuroendocrine tumor (NET) incidentally discovered following a severe perineal tear.</p><p><strong>Case presentation: </strong>A 29-year-old woman experienced a severe perineal tear during the first vaginal delivery, which led to the incidental discovery of a 20-mm rectal NET. Four months after the perineal tear, the gynecology and digestive surgery teams ensured that the tear wound had completely healed and anal function was preserved. The patient underwent robot-assisted ultra-low anterior resection with lymph node dissection. The procedure was successfully completed, preserving anal function, and histopathology confirmed an NET (G2, pT2N2aM0, pStage IIIB). The patient recovered smoothly and was discharged on the seventh postoperative day.</p><p><strong>Conclusions: </strong>Rectal surgery after severe perineal tears may be associated with scarring and fibrosis around the rectum, and precautions should be taken at the time of rectal dissection. Depending on the tumor condition, it may be advisable to perform rectal surgery several months after the tear rather than immediately after treatment for the tear.</p>","PeriodicalId":22096,"journal":{"name":"Surgical Case Reports","volume":"11 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneously Ruptured Pancreatic Mucinous Cystic Neoplasm: A Case Report.","authors":"Masataka Hirano, Masanori Tsujie, Takayoshi Goto, Chikato Koga, Soichiro Mori, Daisuke Takiuchi, Kentaro Nishida, Masatoshi Nomura, Yukihiro Yoshikawa, Koki Tamai, Takuya Hamakawa, Mitsuyoshi Tei, Yusuke Akamaru","doi":"10.70352/scrj.cr.24-0087","DOIUrl":"10.70352/scrj.cr.24-0087","url":null,"abstract":"<p><strong>Introduction: </strong>Pancreatic mucinous cystic neoplasm (MCN) is a cystic tumor of the pancreas typically located in the pancreatic body or tail in middle-aged women. However, MCN rupture is rare. This report describes a case of MCN with spontaneous rupture during follow-up.</p><p><strong>Case presentation: </strong>The patient was a 34-year-old woman. Contrast-enhanced computed tomography (CECT) and magnetic resonance imaging (MRI) revealed a 130 mm multifocal cyst in the pancreatic tail. The cyst, characterized by multiple septa and cyst-in-cyst structures, was diagnosed as an MCN. Initially, the patient opted for periodic follow-ups instead of surgical resection. After a gradual increase in cyst size, surgery was scheduled approximately 1 year later. Two days before the scheduled surgery, the patient experienced unexplained lower abdominal pain. Moreover, CECT revealed a shrinking cystic mass in the pancreatic tail along with the presence of ascites, leading to a diagnosis of spontaneous rupture of the pancreatic cyst. No peritonitis was detected, and a distal pancreatectomy was performed 2 days after admission. Pathological examination confirmed that the pancreatic cyst was a noninvasive mucinous cystadenocarcinoma. The abdominal cavity contained large amounts of turbid ascites with neutrophils but no bacterial growth. Strong inflammatory changes were noted at the cyst wall disruption site. Despite the development of a pancreatic fistula (ISGPF Grade BL, Clavien-Dindo Grade II), the patient was discharged from the hospital on postoperative day 16 and remained alive and recurrence-free for 18 months after surgery.</p><p><strong>Conclusion: </strong>Spontaneous rupture of an MCN is rare. In this study, we report our case and review previously published cases of MCN rupture. We also discuss the potential causes of the spontaneous rupture in our case.</p>","PeriodicalId":22096,"journal":{"name":"Surgical Case Reports","volume":"11 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143504333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Resection of a Pseudoaneurysm of the First Dorsal Metatarsal Artery after Unsuccessful Embolization: A Case Report and Literature Review.","authors":"Hiroto Yasumura, Kenichi Arata, Goichi Yotsumoto, Hideyuki Satozono, Koichiro Shimoishi, Yoshihiro Fukumoto, Yuki Ogata, Tomoyuki Matsuba, Yoshiharu Soga","doi":"10.70352/scrj.cr.24-0020","DOIUrl":"10.70352/scrj.cr.24-0020","url":null,"abstract":"<p><strong>Introduction: </strong>Aneurysms of peripheral foot arteries are extremely rare. Dorsalis pedis artery aneurysms account for 0.5% of peripheral artery aneurysms of the lower limbs. Here, we present a case of pseudoaneurysm of the first dorsal metatarsal artery of the foot and discuss the therapeutic strategy based on a literature review.</p><p><strong>Case presentation: </strong>A 76-year-old man with no history of foot trauma presented with pain and a pounding mass in the dorsum of the left foot. Echography revealed a 29 × 18 × 20 mm saccular aneurysm with to-and-fro blood flow. Contrast-enhanced computed tomography revealed an aneurysm in the first dorsal metatarsal artery. Angiography of the aneurysm revealed no arterial drainage. Embolization was subsequently performed only for the feeding artery, which was the proximal first dorsal metatarsal artery, using the 2 Target nanocoils (Stryker; Boston, MA, USA), resulting in successful occlusion. However, echography performed a few months after embolization revealed a recurrence of blood flow and enlargement of the coiled aneurysm. Nine months after embolization, the pain in the dorsum of the foot recurred. Therefore, we performed a surgical resection of the dorsal metatarsal artery aneurysm (38 × 26 × 26 mm) under general anesthesia. The first distal dorsal metatarsal artery exhibited pulsatile bleeding, and angiography of the distal dorsal metatarsal artery revealed a patent pedal arch and posterior tibial artery. Therefore, revascularization was not performed. The postoperative course was uneventful. The pathological examination indicated that the mass was a pseudoaneurysm.</p><p><strong>Conclusions: </strong>The treatments for peripheral foot artery aneurysms include observation, thrombin injection, ultrasound compression, embolization, surgical excision, and ligation. As the long-term outcomes of embolization for such aneurysms are unknown and cases are limited, surgical excision that is safe and definitive is recommended as the first-line treatment.</p>","PeriodicalId":22096,"journal":{"name":"Surgical Case Reports","volume":"11 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11835978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Right Top Pulmonary Vein Location on Subcarinal Lymph Node Dissection in Thoracoscopic Esophagectomy: A Case Report and Literature Review.","authors":"Takeshi Horaguchi, Yuta Sato, Yuji Hatanaka, Yoshihiro Tanaka, Noriki Mitsui, Masahiro Fukada, Itaru Yasufuku, Ryuichi Asai, Jesse Yu Tajima, Nobuhisa Matsuhashi","doi":"10.70352/scrj.cr.24-0093","DOIUrl":"10.70352/scrj.cr.24-0093","url":null,"abstract":"<p><strong>Introduction: </strong>The right top pulmonary vein (RTPV) is a rare anatomical variant that arises independently of the right superior lobe. It drains behind the right main bronchus or bronchus intermedius and into the left atrium or another pulmonary vein. This anomaly poses challenges during subcarinal lymph node dissection in thoracic surgery, such as esophagectomy, owing to the risk of vascular injury. The RTPV is mainly located behind the right main bronchus and right intermediate bronchus; however, reports of subcarinal dissection focusing on these sites are lacking. Herein, we present a case of esophageal cancer with an RTPV that was treated with thoracoscopic esophagectomy and propose a convenient classification for the anatomical findings and RTPV site.</p><p><strong>Case presentation: </strong>A 71-year-old man underwent a thoracoscopic esophagectomy for esophageal cancer (T1bN0M0) during a routine medical checkup. A preoperative computed tomography scan revealed an anomaly in which the RTPV drained into the left atrium behind the right main bronchus. Radical subcarinal lymphadenectomy was performed while preserving the RTPV, using 3 dimensions for preoperative simulation and intraoperative navigation. The operation lasted 6 h and 42 min, and the blood loss volume was 30 mL. The patient's postoperative course was uneventful, and he was discharged on postoperative day 21.</p><p><strong>Conclusions: </strong>In a retrospective review of esophageal cancer surgery cases at our hospital, RTPV was observed in 17/314 cases (5.4%). The most common inflow site was the inferior pulmonary vein (IPV) (9 cases), followed by the left atrium (5 cases), superior pulmonary vein (2 cases), and superior branch of the IPV (1 case). The inflow site was behind the right main bronchus and the right intermediate bronchus in 4 and 13 cases, respectively. Compared to past reviews, the inflow site varied somewhat; however, the vascular location remained the same. By classifying the areas behind the right main and right intermediate bronchi as Zones 1 and 2, respectively, cases in which the RTPV runs through Zone 1, as identified on preoperative computed tomography, should be manipulated with caution due to the risk of injury during lymph node dissection beneath the tracheal bifurcation.</p>","PeriodicalId":22096,"journal":{"name":"Surgical Case Reports","volume":"11 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11873321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meckel's Diverticulum Mimicking a Postoperative Flange with Acute Intestinal Obstruction and Midgut Volvulus: A Case Report.","authors":"Stéphane Kohpe Kapseu, Venant Tchokonte-Nana","doi":"10.70352/scrj.cr.24-0079","DOIUrl":"https://doi.org/10.70352/scrj.cr.24-0079","url":null,"abstract":"<p><strong>Introduction: </strong>The interest of this case lies in the exceptional and rare character of the observed association.: Meckel's diverticulum (MD) mimicking a postoperative flange complicated by acute intestinal obstruction and malrotation by midgut volvulus.</p><p><strong>Case presentation: </strong>A 17-year-old black male student, with a body mass index of 28 kg/m² was admitted to the emergency department of a 4th category rural hospital, with paroxystic abdominal pain and vomiting. Medical history revealed an abdominal surgery for an umbilical hernia 3 years earlier. There was no malformation such as imperforate anus, Hirschsprung's disease, esophageal tracheal fistula, or cardiac anomaly in the medical history. An abdominal X-ray confirmed an acute intestinal obstruction showing hydroaeric levels. The diagnosis of acute intestinal obstruction on a flange was retained. A median laparotomy was performed; a solid mass-like lengthy structure mimicking postoperative flange was seen associated with midgut volvulus, while a malposition of the intestine was observed with a mesenteric band, as well as a hyperemic appendix. A 90° rotation stop of the midgut also called a complete common mesentery was in place; we then carried out a Ladd procedure. Morpho-pathological examination of the surgical specimens revealed the following: richly vascularized fibro-adipose tissues with no evidence of malignancy in the diverticular specimen, and acute pan-appendicitis with no evidence of malignancy in the appendicular specimen. The patient started to ingest food orally on the third postoperative day, and he was discharged uneventfully on the fifth day.</p><p><strong>Conclusion: </strong>MD, although generally a tubular structure, may sometimes appear as a non-tubular mass during clinical examination. Intestinal obstruction due to MD associated with midgut volvulus is exceptional. Management of this association should be based on accurate knowledge of the morpho-embryological specificities during gut development.</p>","PeriodicalId":22096,"journal":{"name":"Surgical Case Reports","volume":"11 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11868803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Appendicitis Due to Burkitt Lymphoma Masking the Systemic Symptoms of Rapidly Progressing Burkitt Lymphoma.","authors":"Tomoya Masuda, Ryoma Sugimoto, Kenta Kobashi, Hiroshi Ishii, Kensuke Tsunemitsu","doi":"10.70352/scrj.cr.24-0178","DOIUrl":"10.70352/scrj.cr.24-0178","url":null,"abstract":"<p><strong>Introduction: </strong>Primary malignant lymphoma of the appendix is a rare disease, and primary Burkitt lymphoma of the appendix has been reported very rarely in Japan. Burkitt lymphoma is an aggressive lymphoma that progresses more rapidly than other malignant lymphomas, making it sometimes difficult to distinguish between systemic symptoms, such as fever associated with lymphoma progression and fever caused by appendicitis.</p><p><strong>Case presentation: </strong>A 21-year-old man underwent open appendectomy after antibiotic treatment for acute appendicitis proved ineffective. Postoperative pathological findings confirmed acute appendicitis. Antibiotics were continued after surgery, and the patient's fever and abdominal symptoms gradually improved. However, abdominal distension recurred on the 18th day of hospitalization. Blood tests showed a re-elevation of the white blood cell count, suggesting a postoperative intraperitoneal abscess. Despite further antibiotic treatment, fever and leukocytosis persisted. On the 28th day of hospitalization, abnormal lymphocytes were detected in the peripheral blood, and we realized that the persistent fever was due to systemic symptoms of malignant lymphoma rather than a complication of appendicitis. On the 30th day, the patient was referred to the hematology department and subsequently diagnosed with Burkitt lymphoma. Chemotherapy was initiated on the 40th day of hospitalization. At the time of this writing, the patient had remained alive without recurrence for 4 years 3 months postoperatively.</p><p><strong>Conclusion: </strong>In this case, symptoms of acute appendicitis and systemic symptoms of malignant lymphoma appeared simultaneously. As a result, the systemic symptoms of malignant lymphoma were misdiagnosed as postoperative complications, leading to a delay in diagnosis. Primary appendiceal Burkitt lymphoma is extremely rare, and its clinical features remain unknown. It is important to recognize that primary appendiceal Burkitt lymphoma can present with systemic symptoms concurrently with appendicitis. Surgeons should be aware of the clinical features of appendicitis caused by Burkitt lymphoma, which differ from those caused by other appendiceal tumors or malignant lymphoma.</p>","PeriodicalId":22096,"journal":{"name":"Surgical Case Reports","volume":"11 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}