Phytochemistry Letters最新文献_第3页

Declared vs determined: Analysis of cannabinoids in commercially available products on the Maltese market 宣布与确定：马耳他市场上可售产品中大麻素的分析

IF 1.4 4区生物学

Phytochemistry Letters Pub Date : 2026-04-01 Epub Date: 2026-02-20 DOI: 10.1016/j.phytol.2026.104136

Karolina Szyrner , Paul I. Buhagiar , Anthony Serracino-Inglott , Janis Vella Szijj

{"title":"Declared vs determined: Analysis of cannabinoids in commercially available products on the Maltese market","authors":"Karolina Szyrner , Paul I. Buhagiar , Anthony Serracino-Inglott , Janis Vella Szijj","doi":"10.1016/j.phytol.2026.104136","DOIUrl":"10.1016/j.phytol.2026.104136","url":null,"abstract":"<div><div>The Cannabis market is rapidly expanding, with an increasing variety of formulations creating a complex regulatory environment. Products containing cannabis fall under different legislative frameworks. Medicinal cannabis products are regulated under pharmaceutical legislation, while commercially available formulations, including oils and cosmetics, containing low concentrations of delta-9-tetrahydrocannabinol (Δ⁹-THC) fall under a combination of national and European Union (EU) regulations, presenting regulatory and analytical challenges due to fragmented frameworks and the absence of standardised quantification methods. This study aimed to develop and validate a High-Performance Liquid Chromatography with Ultraviolet detection (HPLC-UV) analytical method for the simultaneous quantification of five cannabinoids in commercial cannabis-based oils and cosmetics available in Malta. Validation of the method demonstrated specificity, accuracy, linearity and precision. Analysis of 23 oil and 10 cosmetic products revealed discrepancies between labelled and determined cannabinoid content. THC was detected in 6 samples (0.014–0.165 %), with concentrations below the 0.2 % regulatory threshold, while deviations in cannabidiol (CBD) content exceeded ±10 % label accuracy limit in 19 products. These findings indicate the need for routine quality control and regulatory oversight to ensure consumer safety and product transparency on the Maltase market. Future research should expand this analytical framework to a broader range of cannabis products, including edibles and e-liquid formulations.</div></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"72 ","pages":"Article 104136"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147385252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two new menthane monoterpene derivatives isolated from Hypericum monogynum 从金丝桃中分离的两个新的甲烷单萜衍生物

IF 1.4 4区生物学

Phytochemistry Letters Pub Date : 2026-04-01 Epub Date: 2026-01-19 DOI: 10.1016/j.phytol.2026.104121

Yan-Rong Zeng , Hong-Jin Ban , Jing-Yi Yin , Zhan Feng , Ya-Nan Li , Yan Liu , Xiao-Jiang Hao , Chun-Mao Yuan

引用次数: 0

Oryzaceramides A–C, acylated glucosylceramides with epidermal barrier functions, isolated from rice bran 米酰胺A-C，从米糠中分离出的具有表皮屏障功能的酰化葡萄糖神经酰胺

IF 1.4 4区生物学

Phytochemistry Letters Pub Date : 2026-02-01 Epub Date: 2025-11-26 DOI: 10.1016/j.phytol.2025.104086

Shogo Takeda , Hiroshi Shimoda , Akari Yoneda , Yoshiaki Manse , Toshio Morikawa

引用次数: 0

Triterpenoids from Astragalus armatus subsp. numidicus and their chemotaxonomic significance 黄芪的三萜。Numidicus及其化学分类意义

IF 1.4 4区生物学

Phytochemistry Letters Pub Date : 2026-02-01 Epub Date: 2025-12-08 DOI: 10.1016/j.phytol.2025.104083

Hadjer Boubertakh , Assia Khalfallah , Ahmed Kabouche , Zahia Kabouche , Charlotte Sayagh , Anthony Abou Dib , Laurence Voutquenne-Nazabadioko

引用次数: 0

IF 1.4 4区生物学

Phytochemistry Letters Pub Date : 2026-02-01 Epub Date: 2026-01-02 DOI: 10.1016/j.phytol.2025.104106

Quoc-Vu Pham , Hsin-Wei Wang , Yu-Cheng Chen , Yu-Chia Chang , You-Song Cheng , Yun-Shiuan Chen , Mei-Hsien Lee , Jui-Hsin Su , Bo-Rong Peng , Kuei-Hung Lai

引用次数: 0

Lantapenoids A–C from the aerial parts of Vietnamese Lantana camara 越南大灯笼的空中部分的小灯笼类A-C

IF 1.4 4区生物学

Phytochemistry Letters Pub Date : 2026-02-01 Epub Date: 2025-12-20 DOI: 10.1016/j.phytol.2025.104104

Tran Thi Minh , Tran Thi Minh Trang , Duong Hoang Thuc , Vu Dinh Hoang , Le Dang Quang , Hun Kim , Minh Van Nguyen , Gyung Ja Choi

{"title":"Lantapenoids A–C from the aerial parts of Vietnamese Lantana camara","authors":"Tran Thi Minh , Tran Thi Minh Trang , Duong Hoang Thuc , Vu Dinh Hoang , Le Dang Quang , Hun Kim , Minh Van Nguyen , Gyung Ja Choi","doi":"10.1016/j.phytol.2025.104104","DOIUrl":"10.1016/j.phytol.2025.104104","url":null,"abstract":"<div><div>Two new euphane-type triterpenoids, lantapenoids A and B (<strong>1–2</strong>), a new acyclic monoterpenoid, lantapenoid C (<strong>7</strong>), and four known triterpenoids (<strong>3–6</strong>), along with hispidulin (<strong>8</strong>) and 1,2,3-naphthalenetriol (<strong>9</strong>), were isolated from the dichloromethane extract of the aerial parts of <em>Lantana camara</em> Linn. Their structures were elucidated through extensive analyses of IR, HRESI-MS, 1D, and 2D NMR data, as well as comparison with the published data. <em>In vivo</em> bioassays showed that the dichloromethane extract suppressed <em>Magnaporthe oryzae</em> by 56 % at 3000 µg mL<sup>−1</sup>, while fraction LD1108 (from the dichloromethane extract) exhibited 69 % inhibition against <em>Phytophthora infestans</em> at 2000 µg mL<sup>−1</sup>. Among the nine metabolites, only compound <strong>3</strong> showed <em>in vivo</em> antifungal activity against <em>M. oryzae,</em> with 56 % inhibition at 1000 µg mL<sup>−1</sup>. These results suggested the use of this plant extract and its metabolites as eco-friendly fungicidal agents for controlling plant fungal diseases.</div></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"71 ","pages":"Article 104104"},"PeriodicalIF":1.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145786880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discovery of diterpenoid and sesquiterpenoids as α-glucosidase inhibitors from the leaves of Pieris formosa 从台湾梨叶中发现二萜类和倍半萜类α-葡萄糖苷酶抑制剂

IF 1.4 4区生物学

Phytochemistry Letters Pub Date : 2026-02-01 Epub Date: 2025-11-25 DOI: 10.1016/j.phytol.2025.104085

Jiaxing Yu , Adila Abudurexiti , Guangmin Yao

引用次数: 0

Phytochemistry and therapeutic applications of Ficus religiosa: A comprehensive review 榕树植物化学及治疗应用综述

IF 1.4 4区生物学

Phytochemistry Letters Pub Date : 2026-02-01 Epub Date: 2025-12-16 DOI: 10.1016/j.phytol.2025.104096

Dhananjay Sharma , Luxita Sharma

{"title":"Phytochemistry and therapeutic applications of Ficus religiosa: A comprehensive review","authors":"Dhananjay Sharma , Luxita Sharma","doi":"10.1016/j.phytol.2025.104096","DOIUrl":"10.1016/j.phytol.2025.104096","url":null,"abstract":"<div><h3>Background</h3><div>Traditional ethnomedicine has long recognized numerous plants as natural therapeutic remedies, and approximately 25 % of modern pharmaceutical drugs are derived from plant-based phytochemicals. <em>Ficus religiosa</em>, a prominent species of the Moraceae family and widely known as the Peepal tree in India, holds a significant place in traditional medicinal systems such as Ayurveda, Unani, and Siddha. Various parts of the plant, including the stem, bark, roots, fruits, and latex, have been extensively explored for their medicinal potential.</div></div><div><h3>Objectives</h3><div>This review aims to provide a comprehensive and updated overview of the traditional uses, phytochemical composition, nutritional values, phytopharmacological activities, and contemporary therapeutic applications of <em>Ficus religiosa</em>.</div></div><div><h3>Key Findings</h3><div>Scientific literature demonstrates that <em>F. religiosa</em> contains a rich diversity of bioactive phytochemicals, including flavonoids, phenolic compounds, dietary fibers, antioxidants, serotonin, vitamins, minerals, and other essential nutrients. These constituents contribute to a broad spectrum of <em>pharmacological</em> activities such as antioxidant, anti-inflammatory, antidiabetic, antimicrobial, neuroprotective, and wound-healing effects. Recent research continues to isolate and characterize new compounds from <em>F. religiosa</em>, further supporting its therapeutic relevance. Compared to synthetic drugs, plant-derived compounds often exhibit lower adverse effects, making them valuable candidates for drug development.</div></div><div><h3>Conclusion</h3><div><em>Ficus religiosa</em> exhibits significant pharmacological potential supported by both traditional knowledge and contemporary scientific evidence. Given its diverse phytochemical profile and wide range of therapeutic properties, this plant represents a promising natural resource for future pharmacological research and drug discovery.</div></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"71 ","pages":"Article 104096"},"PeriodicalIF":1.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145786879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of flavonols in the leaves of daikon (Raphanus sativus L.) 白萝卜叶中黄酮醇的鉴定

IF 1.4 4区生物学

Phytochemistry Letters Pub Date : 2026-02-01 Epub Date: 2025-11-25 DOI: 10.1016/j.phytol.2025.104077

Natsu Tanikawa , Hiroshi Ueda , Fumi Tatsuzawa

{"title":"Identification of flavonols in the leaves of daikon (Raphanus sativus L.)","authors":"Natsu Tanikawa , Hiroshi Ueda , Fumi Tatsuzawa","doi":"10.1016/j.phytol.2025.104077","DOIUrl":"10.1016/j.phytol.2025.104077","url":null,"abstract":"<div><div>Radish (<em>Raphanus sativus</em> L.) is a widely used cruciferous vegetable. Japanese radish, daikon, is one of the most consumed vegetables in Japan. Its large white roots are mainly used as root vegetables. The leaves are not widely used but are known to possess high nutritional value, and contain flavonoids, the plant-derived food components with various human health benefits. In general, flavonoids need to be hydrolyzed to aglycones before absorption and the biological efficacy of flavonoids has been mainly examined in terms of the type of aglycone present. However, it has been reported that flavonoids can also exert various effects in their native state before absorption. In this study, we used HPLC analysis and detected multiple flavonoid components in daikon leaves, but not in the roots. In order to clarify which flavonoids are present in daikon leaves, we isolated them from the leaves and elucidated their structures by HR-MS and NMR analyses. We identified two new flavonols, kaempferol 3-<em>O</em>-β-arabinopyranoside-7-<em>O</em>-[3-<em>O</em>-(4-<em>O</em>-β-glucopyranosyl-6-<em>O</em>-<em>trans</em>-caffeoyl-β-glucopyranosyl)-α-rhamnopyranoside] and kaempferol 3-<em>O</em>-α-rhamnopyranoside-7-<em>O</em>-[3-<em>O</em>-(4-<em>O</em>-β-glucopyranosyl-6-<em>O</em>-<em>trans</em>-caffeoyl-β-glucopyranosyl)-α-rhamnopyranoside] along with two known quercetin glycosides and four known kaempferol glycosides. A unique characteristic we observed in them was their glycosylation pattern with rhamnose at the 7-position and with sugars of different kinds (galactose, glucose, arabinose, or rhamnose) at the 3-position of aglycone. These glycosylation patterns and types of sugars were different from those identified in members of the genus <em>Brassica</em> that are used as vegetables, indicating different mechanisms of action for these compounds in daikon.</div></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"71 ","pages":"Article 104077"},"PeriodicalIF":1.4,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145616948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two new compounds isolated from a sponge-derived fungus Diaporthe sp. ZYX-Z-582 从海绵体真菌Diaporthe sp. ZYX-Z-582中分离得到两个新化合物

IF 1.4 4区生物学

Phytochemistry Letters Pub Date : 2026-02-01 Epub Date: 2026-01-05 DOI: 10.1016/j.phytol.2025.104109

Jia-Le Chang , Qing-Yun Ma , Li Yang , Qing-Yi Xie , Hai-Tao Li , Jiao-Cen Guo , Hao-Fu Dai , Sha-Sha Liu , You-Xing Zhao

引用次数: 0