Nutrition ResearchPub Date : 2026-01-01Epub Date: 2025-12-13DOI: 10.1016/j.nutres.2025.12.003
Sha Li, Ming Xiao
{"title":"Association between HEI-2020 and sarcopenia in US adults: A study based on the 2011-2018 NHANES data","authors":"Sha Li, Ming Xiao","doi":"10.1016/j.nutres.2025.12.003","DOIUrl":"10.1016/j.nutres.2025.12.003","url":null,"abstract":"<div><div>This research intends to ascertain the link between Healthy Eating Index 2020 (HEI-2020) and sarcopenia in US adults. Data from the 2011-2018 National Health and Nutrition Examination Survey (NHANES) were utilized for this cross-sectional analysis. Weighted logistic regression and subgroup analyses were performed to ascertain the independent association between HEI-2020 and sarcopenia. A restricted cubic spline (RCS) approach was employed to examine the dose-response link between HEI-2020 and sarcopenia. Additionally, Weighted Quantile Sum (WQS) regression was leveraged to evaluate links between individual components of HEI-2020 and sarcopenia. The analysis included 8467 participants in total. The median HEI-2020 score was 49.48, and the overall prevalence of sarcopenia was 8.69%. The prevalence of sarcopenia was substantially lower among participants in the highest quartile of HEI-2020 (Q4) than among those in the lowest quartile (Q1) (OR = 0.537, 95% CI: 0.371-0.779, <em>P</em> = .002). A linearly negative correlation between HEI-2020 and sarcopenia was found by the RCS analysis. Interaction analyses indicated significant heterogeneity across age subgroups. WQS analysis identified 13 dietary components that collectively exhibited a protective effect on sarcopenia risk, with dairy products emerging as the most influential component. In conclusion, in US individuals, the risk of sarcopenia was negatively correlated with higher HEI-2020 scores. Higher HEI-2020 scores indicate a healthy diet,which may lower the risk of sarcopenia and hold the potential for informing dietary recommendations in clinical settings.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"145 ","pages":"Pages 102-111"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145885012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition ResearchPub Date : 2026-01-01Epub Date: 2025-11-27DOI: 10.1016/j.nutres.2025.11.010
Ludovico Abenavoli , Nazarii Kobyliak , Anna Kukharchuk , Oleksandra Chervona , Yulia Shvets , Giuseppe Guido Maria Scarlata , Domenico Morano , Elina Christian , Nataliia Molochek , Oksana Lynchak , Yurii Hnativ , Tetyana Falalyeyeva
{"title":"The Mediterranean diet: historical benefits and contemporary challenges in Southern Italy","authors":"Ludovico Abenavoli , Nazarii Kobyliak , Anna Kukharchuk , Oleksandra Chervona , Yulia Shvets , Giuseppe Guido Maria Scarlata , Domenico Morano , Elina Christian , Nataliia Molochek , Oksana Lynchak , Yurii Hnativ , Tetyana Falalyeyeva","doi":"10.1016/j.nutres.2025.11.010","DOIUrl":"10.1016/j.nutres.2025.11.010","url":null,"abstract":"<div><div>The Mediterranean diet (MedDiet) is an ancient traditional way of eating that is characteristic of the territory of Southern Italy, Greece, and the island of Crete. For more than a decade, studies have been conducted that demonstrate the benefits of this type of diet, namely a reduction in the risk of cardiovascular disease, obesity, and increased life expectancy, etc. This eating pattern is characterized by a wealth of plant foods, olive oil, and moderate consumption of dairy products, fish and red wine. However, in recent decades, there has been a rapid spread of the Western eating pattern, which is characterized by high consumption of processed foods, fast food, sugary drinks, and foods rich in saturated fats and added sugars. Modern nutritional trends are replacing the traditional MedDiet. This global shift in eating habits has led to an alarming increase in obesity rates among both adults and children, particularly in regions that are historically the birthplace of the MedDiet. This narrative review aims to explore and analyze the historical influence of the MedDiet on the formation of eating habits among the inhabitants of Southern Italy. The novelty is that it presents the first investigation researching the correlation between the shift away from the traditional MedDiet and the rising prevalence of childhood obesity in Southern Italy based on current epidemiological data. The selection of sources was carried out in the scientific databases PubMed, Scopus, and Web of Science using specific keywords.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"145 ","pages":"Pages 37-47"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145781591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition ResearchPub Date : 2026-01-01Epub Date: 2025-11-21DOI: 10.1016/j.nutres.2025.11.007
Menşure Nur Çelik , Emine Karademir , Murat Gürbüz
{"title":"The integration of artificial intelligence-generated diets into the field of dietetics: Synergy or threat?","authors":"Menşure Nur Çelik , Emine Karademir , Murat Gürbüz","doi":"10.1016/j.nutres.2025.11.007","DOIUrl":"10.1016/j.nutres.2025.11.007","url":null,"abstract":"<div><div>The objective of this study was to conduct a comparative analysis of diets generated by artificial intelligence (AI) tools (ChatGPT-4o and Gemini Advanced) and those prescribed by dietitians. Each researcher (n: 3) obtained 15-day diet plans from AI in separate accounts and 3-day diet plans from five dietitians. In total, 135 diet plans were obtained for each researcher, 45 from ChatGPT-4o, 45 from Gemini, and 45 from dietitians. Diet plans were entered into the BeBis v9.0 program. Nutrient Rich Foods (NRF)15.3 scores, estimated glycemic index(GI) score, saturated fatty acid(SFA)/unsaturated fatty acid ratio, MUFA/PUFA ratio, ω-6/ω-3 ratio, amino acid (AA) score, and composite dietary antioxidant index(CDAI) score were evaluated. ChatGPT-4o achieved the highest trient NRF15.3 score, while Gemini Advanced achieved the highest AA score despite overall inadequate protein quality. AI tools exhibited a significantly lower percentage of energy from SFA(%), SFA/USFA, and SFA/PUFA ratio in comparison with diets prescribed by dietitians. The diets produced by Gemini Advanced demonstrated the highest MUFA/PUFA ratio. All diet plans were within the acceptable range in terms of the ω-6/ω-3 ratio, with no significant differences between the groups. While no significant differences were found in the estimated GI, dietitian-prescribed diets achieved significantly higher CDAI, suggesting greater antioxidant capacity in their overall menu composition. These findings suggest that AI tools can generate nutritionally sound diets with only minor deviations from those prepared by dietitians, potentially enhancing efficiency and reducing workload; however, human oversight remains essential to ensure nutritional adequacy, address micronutrient gaps, and guide critical dietary decisions.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"145 ","pages":"Pages 25-36"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145750309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition ResearchPub Date : 2026-01-01Epub Date: 2025-12-11DOI: 10.1016/j.nutres.2025.11.006
Javad Barouei , Alice Martinic , Zach Bendiks , Darya Mishchuk , Dustin Heeney , Carolyn M. Slupsky , Maria L. Marco
{"title":"Erratum to “Type 2–resistant starch and Lactiplantibacillus plantarum NCIMB 8826 result in additive and interactive effects in diet-induced obese mice” [Nutrition Research Volume 118, October 2023, Pages 12-28]","authors":"Javad Barouei , Alice Martinic , Zach Bendiks , Darya Mishchuk , Dustin Heeney , Carolyn M. Slupsky , Maria L. Marco","doi":"10.1016/j.nutres.2025.11.006","DOIUrl":"10.1016/j.nutres.2025.11.006","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"145 ","pages":"Page 112"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145743269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition ResearchPub Date : 2025-12-01Epub Date: 2025-11-01DOI: 10.1016/j.nutres.2025.10.008
Wuttyi Khaing, Uyangamaa Nyamsuren, Sangah Shin
{"title":"Association between dairy consumption and metabolic dysfunction-associated steatotic liver disease among Korean adults: Evidence from the prospective health examinees cohort","authors":"Wuttyi Khaing, Uyangamaa Nyamsuren, Sangah Shin","doi":"10.1016/j.nutres.2025.10.008","DOIUrl":"10.1016/j.nutres.2025.10.008","url":null,"abstract":"<div><div>Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as a salient public health concern. Dietary factors, including dairy intake, have been identified as potential risk factors; however, evidence in Asian populations remains limited. This prospective cohort study aimed to examine the association between dairy product consumption and MASLD risk among Korean adults using data from the Health Examinees study. A total of 44,471 participants aged 40-69 years and without any liver disease at baseline were included. Dairy intake for milk, yogurt, and cheese was evaluated using a validated food frequency questionnaire. MASLD was defined by the fatty liver index (FLI) ≥60. Cox proportional hazards models were used to estimate hazard ratio (HR) and 95% confidence interval (CI), with adjustments for sociodemographic, lifestyle, and dietary factors. During an average follow-up of 4.5 years, 760 incident MASLD cases occurred in men and 786 in women. Higher total dairy consumption was associated with a lower risk of MASLD in men. Specifically, those with the highest intake of milk and yogurt had a significantly lower risk compared to those with the lowest intake (total dairy consumption, HR 0.79 [95% CI 0.61-0.98]; milk, HR 0.74 [95% CI 0.57-0.96]; yogurt, HR 0.79 [95% CI 0.64-0.97]). No significant associations were observed for cheese consumption or among women. These findings indicate a potential inverse association between milk and yogurt intake and MASLD risk in Korean men, but not in women, suggesting sex-specific dietary influences on liver health. Given the observational design, causal inference cannot be made.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"144 ","pages":"Pages 38-49"},"PeriodicalIF":3.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145615350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Probiotic-fermented milk alleviates hypertension in preeclampsia rats and is associated with increases in branched fatty acid esters of hydroxy fatty acids","authors":"Tingyi Ke, Tiemin Jiang, Haiyun Li, Xinhong Dong, Hock Eng Khoo","doi":"10.1016/j.nutres.2025.10.004","DOIUrl":"10.1016/j.nutres.2025.10.004","url":null,"abstract":"<div><div>Branched fatty acid esters of hydroxy fatty acids (FAHFAs), a newly-discovered class of endogenous lipids closely associated with obesity, cardiovascular disease, and aging, are potential drug candidates or targets for the prevention and treatment of related conditions. The antihypertensive potential of probiotic-fermented milk has been recognized, but its relevance to preeclampsia (PE) is unclear. It was hypothesized that probiotic-fermented milk could reduce blood pressure in PE rats and influence the contents of FAHFAs, with FAHFAs potentially playing a critical role in this process. To test this hypothesis, the PE rat model was constructed using L-NAME (125 mg/kg), and probiotic-fermented milk (20 mg/kg) was administered for a total of 21 d. Metagenomic sequencing and LC—MS/MS based metabolomics were used. Probiotic-fermented milk substantially attenuated hypertension in PE rats, with an efficacy comparable to that of labetalol (4 mg/kg). Probiotic-fermented milk significantly increased the contents of specific FAHFAs (e.g., 18:0/20:2, 16:0/18:2) in the gut and serum (<em>P</em> < .05) and FAHFAs was negatively correlated with blood pressure (<em>P</em> < .05). Probiotic-fermented milk regulated the composition of gut microbiota (increasing <em>Lactiplantibacillus</em> and <em>Staphylococcus</em> and decreasing <em>Methanobrevibacter</em> and <em>Limosilactobacillus</em>), and down-regulated purine, glyoxylate/dicarboxylate, and amino metabolism, and the one-carbon pool produced by folate. These metabolic shifts were strongly correlated with the gut microbiota and FAHFAs. These results indicate that probiotic-fermented milk alleviates hypertension in PE rats, potentially mediated by FAHFAs. This study provides foundational evidence for the antihypertensive mechanism of probiotic-fermented milk in preeclampsia and supports the development of novel strategies for its prevention and treatment.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"144 ","pages":"Pages 1-15"},"PeriodicalIF":3.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145442277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}