Nutrition Research最新文献

{"title":"Healthful plant-based diets are negatively associated with the rate of biological aging: A national study based on US adults","authors":"Jia Wang ,&nbsp;Chen Yang ,&nbsp;Xue Dong ,&nbsp;Yining Huang ,&nbsp;Yuchen Cong ,&nbsp;Lei Wang ,&nbsp;Zhenkang Qiu ,&nbsp;Bin Cao","doi":"10.1016/j.nutres.2024.10.005","DOIUrl":"10.1016/j.nutres.2024.10.005","url":null,"abstract":"<div><div>Plant-based diets are recognized for their health benefits. However, evidence on the association between plant-based diet quality and aging in the US population is limited. This study aimed to investigate the association between different plant-based diet indices, phenotypic age acceleration (PhenoAgeAccel), and biological age acceleration (BioAgeAccel). We hypothesized that healthful plant-based diets would negatively affect PhenoAgeAccel and BioAgeAccel in US adults. The cross-sectional analysis included 22,363 participants, and information was obtained from the National Health and Nutrition Examination Survey database. The quality of plant-based diet was assessed using 3 indices: overall plant-based diet index (PDI), healthful PDI (hPDI), and unhealthful PDI (uPDI). Phenotypic age (PA) and biological age (BA) was calculated based on a linear combination of chronological age and 12 multi-system clinical chemistry biomarkers in accordance with the previously established method. PhenoAgeAccel and BioAgeAccel are the residuals of the PA and BA. Weighted linear regression analyses were performed to evaluate the relationships between PDI, hPDI and uPDI, and PhenoAgeAccel and BioAgeAccel. After adjusting for all covariates, we observed that a 10-unit higher PDI score was associated with 0.80 years lower PhenoAgeAccel (β: -0.80, 95% confidence interval [CI]: -0.94, -0.67), and 1.91 years lower BioAgeAccel (β: -1.91, 95% CI: -2.42,-1.40). A 10-unit higher hPDI score was associated with 0.83 years lower PhenoAgeAccel (β: -0.83, 95% CI: -0.96, -0.70), and 1.76 years lower BioAgeAccel (β: -1.76, 95% CI: -2.18, -1.34). Conversely, a 10-unit higher uPDI score was associated with 0.77 years higher PhenoAgeAccel (β: 0.77, 95% CI: 0.66, 0.89) and 1.21 years higher BioAgeAccel (β: 1.21, 95% CI: 0.80, 1.62). These findings suggest that US adults may be able to slow the aging process by increasing adherence to a healthy plant-based diet.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"132 ","pages":"Pages 112-124"},"PeriodicalIF":3.4,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary Inflammatory Index is associated with periodontitis risk in pregnant women with gestational diabetes mellitus","authors":"Ru-Lin Liu ,&nbsp;Xiao-Qian Chen ,&nbsp;Jing Liu ,&nbsp;Qing-Xiang Zheng ,&nbsp;Xiu-Min Jiang ,&nbsp;Jia-Ning Li ,&nbsp;Ling Huang ,&nbsp;Yu Zhu","doi":"10.1016/j.nutres.2024.10.001","DOIUrl":"10.1016/j.nutres.2024.10.001","url":null,"abstract":"<div><div>Recent studies suggest a link between periodontitis and the Dietary Inflammatory Index (DII). We hypothesize that a more proinflammatory diet is associated with periodontitis risk in pregnant women with gestational diabetes mellitus (GDM). This study aimed to explore the association between DII scores and periodontitis risk in GDM women. In this cross-sectional study, 302 eligible GDM women from a Maternal and Child Health Hospital were enrolled between February and July 2023. DII scores were calculated based on dietary intake data collected using a validated semiquantitative food frequency questionnaire. Periodontal health was assessed through periodontal parameters including bleeding on probing, probing depth, and clinical attachment loss. Logistic regression models were employed to evaluate the odds ratios (ORs) for periodontitis risk across DII tertiles. Our study found that the prevalence of periodontitis across the DII tertiles 1, 2, and 3 was 34.7%, 56.4%, and 54.0%, respectively. Comparing the highest DII tertile (tertile 3) with the lowest (tertile 1), a significant association was found between higher DII scores and periodontitis risk (univariate OR: 2.21; 95% CI: 1.25, 3.90; <em>P</em> = .006), which remained significant in the fully adjusted model (adjusted OR: 2.30; 95% CI: 1.21, 4.37; <em>P</em> = .011). In conclusion, elevated DII scores are associated with an increased risk of periodontitis, underscoring the crucial role of a proinflammatory diet in periodontitis progression. Future well-designed experimental studies are needed to verify if tailored dietary strategies can effectively reduce periodontitis risk among pregnant women with GDM.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"132 ","pages":"Pages 85-94"},"PeriodicalIF":3.4,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Altered intestinal microbiota induced by high-fat diets affect cognition differently in mice","authors":"Yinan Hua ,&nbsp;Cui Zhou ,&nbsp;Rong Fan ,&nbsp;Sara Benazzouz ,&nbsp;Jingyi Shen ,&nbsp;Rong Xiao ,&nbsp;Weiwei Ma","doi":"10.1016/j.nutres.2024.09.019","DOIUrl":"10.1016/j.nutres.2024.09.019","url":null,"abstract":"<div><div>The role of the gut microbiota in the association between high-fat diet and cognition is not clear. We hypothesized that a high-fat diet may influence cognition by altering the intestinal microbiota. Fecal microbiota isolated from male C57BL/6J mice feeding on various high-fat diets and a control basic diet were transplanted to antibiotic-treated recipient mice. The measurement of weight and plasma lipids, novel object recognition test, 16S rRNA gene sequencing of feces, and hematoxylin-eosin staining of the hippocampal cornu ammonis 1 and cornu ammonis 3 areas were performed for all mice. Compared with those in the control and n-3 polyunsaturated fatty acid (n-3 PUFA) groups, donor obese mice fed with diets high in long-chain saturated fatty acids, n-6 polyunsaturated fatty acids (n-6 PUFAs), and trans fatty acids exhibited significant cognitive impairment (all <em>P</em> &lt; .05). There were fewer neurons in the hippocampal area in the n-6 PUFA group than in the n-3 PUFA group (<em>P</em> &lt; .05). Similar effect on cognition and neurons in hippocampal area in corresponding recipient mice were revealed after fecal microbiota transplantation. In addition, the composition of intestinal microbiota differed among recipient mice after fecal microbiota transplantation from donor mice. According to these results, it was concluded that diets rich in long-chain saturated fatty acids, n-6 PUFAs, and trans fatty acids may lead to cognitive impairment by damaging the structure of the hippocampus through influencing the intestinal microbiota in mice, whereas a diet high in n-3 PUFAs may exhibit a beneficial effect.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"132 ","pages":"Pages 67-84"},"PeriodicalIF":3.4,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"David Kritchevsky Graduate Student Award for Nutrition Research","authors":"","doi":"10.1016/S0271-5317(24)00137-4","DOIUrl":"10.1016/S0271-5317(24)00137-4","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"130 ","pages":"Page iii"},"PeriodicalIF":3.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial office and Board Members","authors":"","doi":"10.1016/S0271-5317(24)00136-2","DOIUrl":"10.1016/S0271-5317(24)00136-2","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"130 ","pages":"Pages i-ii"},"PeriodicalIF":3.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increasing particle size of oat flours decreases postprandial glycemia and increases appetite in healthy adults","authors":"Corrina Zi Chen Zhou ,&nbsp;G. Harvey Anderson ,&nbsp;Wenxuan Fan ,&nbsp;Shirley Vien ,&nbsp;Yongfeng Ai ,&nbsp;Mehmet Tulbek ,&nbsp;Hrvoje Fabek","doi":"10.1016/j.nutres.2024.07.006","DOIUrl":"10.1016/j.nutres.2024.07.006","url":null,"abstract":"<div><div>Consumption of oats is associated with lowered risks of type 2 diabetes and obesity. However, many oat-based products (e.g., breakfast cereals) use finely milled flours but are associated with health claims based on oats of larger particle sizes. The objective of this study was to test the hypothesis that increasing oat flour particle size will result in lower postprandial glycemia and appetite. Using a randomized-controlled, crossover design, 20 participants (10 males, 10 females; age: 25.3 ± 1.0 years; body mass index: 23.2 ± 0.6 kg/m²) consumed a serving of porridge made using 40 g of coarse (675.7 ± 19.6 µm), whole (443.3 ± 36.2 µm), fine (96.0 ± 2.1 µm), or a commercial (375.9 ± 14.8 µm) oat flour unmatched in available carbohydrate, protein, and dietary fiber content. After a 12-hour overnight fast, blood glucose, insulin, and appetite were measured at 15 to 30-minute intervals over 120 minutes posttreatment consumption. Coarse and whole flours led to lower blood glucose between 30 and 60 minutes (<em>P</em> &lt; .02). Blood glucose area under the curve (AUC) was lower after coarse than fine and commercial oat flours (<em>P</em> &lt; 0.03), and after whole than fine oat flour (<em>P</em> &lt; .002). Both coarse and whole oat flours resulted in lower insulin AUC than finer flours (<em>P</em> &lt; .05). Appetite AUC was lower after the commercial than coarse flour (<em>P</em> &lt; .007). Controlling milling to produce coarser oat flour to add to common foods may have health benefits. This study was registered at ClinicalTrials.gov (NCT05291351).</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"130 ","pages":"Pages 81-94"},"PeriodicalIF":3.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gut microbiota and inflammation analyses reveal the protective effect of medium-chain triglycerides combined with docosahexaenoic acid on cognitive function in APP/PS1 and SAMP8 mice","authors":"Zehao Wang ,&nbsp;Yue Sun ,&nbsp;Dalong Zhang ,&nbsp;Yue Wang ,&nbsp;Dezheng Zhou ,&nbsp;Wen Li ,&nbsp;Jing Yan ,&nbsp;Yongjie Chen ,&nbsp;Suhui Luo ,&nbsp;Zhiyong Qian ,&nbsp;Zhenshu Li ,&nbsp;Guowei Huang","doi":"10.1016/j.nutres.2024.09.015","DOIUrl":"10.1016/j.nutres.2024.09.015","url":null,"abstract":"<div><div>Accumulating evidence has demonstrated that medium-chain triglycerides (MCTs) and docosahexaenoic acid (DHA) positively affect cognitive function. However, it remains unclear whether the improvement is related to the alterations of gut microbiota and inflammation and the impact of the combined intervention. In this study, we hypothesized that the supplementation of MCTs combined with DHA could modulate gut microbiota, inflammation, and improve cognitive function in APPswe/PS1De9 model mice and senescence-accelerated mouse-prone-8, which are two different mouse models used in neurodegeneration research. The mice were divided into four groups: Control group, MCTs group, DHA group, and MCTs + DHA group. The study assessed cognitive function, inflammatory cytokines, and gut microbiota composition. The results showed that supplementation of MCTs + DHA improved spatial learning ability, memory capacity, exploratory behavior; decreased the relative abundance of <em>Proteobacteria</em>; reduced the ratio of <em>Firmicutes</em>/<em>Bacteroidetes</em>; decreased the concentrations of serum interleukin (IL)-2, IL-6, monocyte chemotactic protein-1, tumor necrosis factor-alpha, while increasing the concentration of IL-10. Furthermore, supplementation with MCTs + DHA exhibited significantly superior effects compared to MCTs or DHA alone in reducing inflammation, optimizing gut microbiota composition, and improving cognitive function. In conclusion, supplementation with MCTs + DHA improved cognition function, accompanied with favorable alterations in gut microbiota and inflammation in APPswe/PS1De9 and senescence-accelerated mouse-prone-8 mice.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"132 ","pages":"Pages 27-39"},"PeriodicalIF":3.4,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142504901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High dietary antioxidant index associated with reduced insulin resistance in female Mexican children and adolescents","authors":"Rogelio F. Jiménez-Ortega ,&nbsp;Joacim Meneses-León ,&nbsp;Sonia Hernández ,&nbsp;Priscila Thebar-Moreno ,&nbsp;Diana I. Aparicio-Bautista ,&nbsp;Adriana Becerra-Cervera ,&nbsp;Carlos Aguilar-Salinas ,&nbsp;Jorge Salmerón ,&nbsp;Berenice Rivera-Paredez ,&nbsp;Rafael Velázquez-Cruz","doi":"10.1016/j.nutres.2024.09.016","DOIUrl":"10.1016/j.nutres.2024.09.016","url":null,"abstract":"<div><div>Antioxidant intake is inversely associated with different health outcomes; however, its association with insulin resistance (IR) has not been well documented. We hypothesized that the Dietary Antioxidant Index (DAI) is inversely associated with IR in Mexican children and adolescents. A cross-sectional analysis was performed using data from the Health Workers Cohort Study. A total of 830 children and adolescents aged 7 to 18 years were enrolled. The DAI was evaluated in three categories defined by tertiles using a semiquantitative food frequency questionnaire. IR was defined using previously reported cutoff points in the homeostasis model assessment. This association was evaluated using a multiple logistic regression model. Stratified analysis was performed using body mass index and sex. The prevalence of IR based on the DAI categories (low, medium, high) was 23.8%, 24.2%, and 15.3%, respectively. The IR odds ratio (OR) for participants in the highest DAI category was 0.49 (95% confidence interval [CI]: 0.30-0.80). Notably, female Children and Adolescents in the highest DAI category had significantly lower odds of developing IR than those in the lowest DAI category (OR 0.54, 95% CI 0.29-0.98). Participants with overweight/obesity showed a similar association (OR 0.37, 95% CI 0.18-0.76). These results suggest that the DAI is inversely associated with IR, particularly in females, highlighting the potential role of antioxidants in preventing IR. This underscores the need to establish recommendations for antioxidant consumption in female children and adolescents.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"132 ","pages":"Pages 53-66"},"PeriodicalIF":3.4,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142504902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved metabolic stability in iNOS knockout mice with Lactobacillus supplementation","authors":"Hobby Aggarwal ,&nbsp;Jyoti Gautam ,&nbsp;Sonu Kumar Gupta ,&nbsp;Bhabatosh Das ,&nbsp;Yashwant Kumar ,&nbsp;Kumaravelu Jagavelu ,&nbsp;Madhu Dikshit","doi":"10.1016/j.nutres.2024.09.018","DOIUrl":"10.1016/j.nutres.2024.09.018","url":null,"abstract":"<div><div>Oxidative and nitrosative stress play pivotal roles in normal physiological processes and the pathogenesis of metabolic disorders. Previous studies from our lab demonstrated insulin resistance (IR), and dyslipidemia in iNOS^−/− mice, emphasizing the importance of maintaining optimal redox balance. These mice exhibited altered gut microbiota with decreased <em>Lactobacillus</em>. Therefore, we hypothesized that <em>Lactobacillus</em> supplementation could mitigate metabolic disturbances in iNOS^−/− mice. To test this hypothesis, iNOS^−/− mice and wild-type (WT) mice were divided into four groups: iNOS^−/- with or without Lactobacillus supplementation, WT with or without Lactobacillus supplementation and glucose tolerance, insulin resistance, gluconeogenesis, lipids, gene expression related to glucose and lipid metabolism (qPCR), fecal gut microbiota (16S rRNA sequencing), and serum and caecum metabolomics (LC-MS) were monitored. IR and dyslipidemic iNOS^−/− mice exhibited reduced microbial diversity, diminished presence of <em>Lactobacillus</em>, and altered serum metabolites, indicating metabolic dysregulation. <em>Lactobacillus</em> supplementation in iNOS^−/− mice effectively reversed glucose intolerance, IR, dyslipidemia, and associated metabolic irregularities compared to WT. These improvements correlated with changes in gene expression related to fatty acid synthesis in liver and adipose tissue, lipid oxidation in liver, and lipid efflux in intestinal tissue as compared to untreated iNOS^−/− mice. Despite the positive effects on metabolic markers, <em>Lactobacillus</em> supplementation did not reduce body weight or rectify disrupted energy balance, as evidenced by reduced VCO₂ production, heat generation, and metabolic rates in iNOS^−/− mice. The results suggest that <em>Lactobacillus</em> supplementation ameliorates metabolic disturbances but did not fully restore disrupted energy balance, highlighting complex interactions between the gut microbiome and metabolism.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"132 ","pages":"Pages 95-111"},"PeriodicalIF":3.4,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142624993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary metals are associated with obesity in U.S. children and adolescents: A cross-sectional study","authors":"Xinyun Zhou,&nbsp;Hongliang Jin,&nbsp;Yan Zhang","doi":"10.1016/j.nutres.2024.09.017","DOIUrl":"10.1016/j.nutres.2024.09.017","url":null,"abstract":"<div><div>Heavy metals are pervasive in the environment, and exposure to these metals may contribute to obesity in children and adolescents. We hypothesized that metal exposures are associated with obesity in children and adolescents. Data were drawn from children and adolescents aged 6 to 19 years from the 2007 to 2018 National Health and Nutrition Examination Survey. We employed weighted multivariate logistic regression and restricted cubic spline to explore the effects of individual metal exposures on obesity, and weighted quantile sum regression, quantile g-computed regression, and Bayesian kernel machine regression to explore the effects of mixed metal exposures on obesity. Subgroup analyses by gender were also performed. All models were adjusted for age, gender, race, poverty to income ratio, and serum cotinine. Among the 3,650 children and adolescents studied, 21.04% had obesity. Logistic regression revealed positive associations between barium (OR = 1.23, 95% CI: 1.07-1.40) and thallium (OR = 1.55, 95% CI: 1.23-2.15) with obesity, while cadmium (OR = 0.74, 95% CI: 0.61-0.89), cobalt (OR = 0.51, 95% CI: 0.41-0.62), and lead (OR = 0.70, 95% CI: 0.57-0.86) were negatively associated with obesity. Restricted cubic spline indicated a nonlinear relationship between lead and thallium and obesity. Quantile g-computed regression demonstrated that mixed metal exposure was negatively associated with obesity (OR = 0.50, 95% CI: 0.42-0.59). Subgroup analyses revealed a gender-specific effect for mercury (<em>P</em> for interaction = 0.03), which was negatively associated with obesity in females (OR = 0.83, 95% CI: 0.69-0.99). In conclusion, metal exposures are associated with obesity in children and adolescents, with gender differences.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"132 ","pages":"Pages 40-52"},"PeriodicalIF":3.4,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142504903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}