Nutrition Research最新文献_第5页

David Kritchevsky Graduate Student Award for Nutrition Research 大卫-克里切夫斯基营养研究研究生奖

IF 3.4 3区医学

Nutrition Research Pub Date : 2024-07-01 DOI: 10.1016/S0271-5317(24)00095-2

引用次数: 0

Editorial office and Board Members 编辑部和董事会成员

IF 3.4 3区医学

Nutrition Research Pub Date : 2024-07-01 DOI: 10.1016/S0271-5317(24)00094-0

引用次数: 0

Upcycled canola meal extract mitigates UVB-induced skin wrinkling by regulating photoaging-related biomarkers in hairless mice 回收菜籽粕提取物通过调节无毛小鼠的光敏相关生物标志物，减轻紫外线引起的皮肤皱纹。

IF 3.4 3区医学

Nutrition Research Pub Date : 2024-07-01 DOI: 10.1016/j.nutres.2024.06.002

Gi-Cheol Park , Inil Lee , Jisuk Yun , Jae Sung Hwang , Dae-Ok Kim

{"title":"Upcycled canola meal extract mitigates UVB-induced skin wrinkling by regulating photoaging-related biomarkers in hairless mice","authors":"Gi-Cheol Park , Inil Lee , Jisuk Yun , Jae Sung Hwang , Dae-Ok Kim","doi":"10.1016/j.nutres.2024.06.002","DOIUrl":"10.1016/j.nutres.2024.06.002","url":null,"abstract":"<div>Canola meal, a by-product of processing canola into oil, reportedly contains high amounts of phenolic compounds and proteins. However, as canola meal is primarily used as feed for livestock, advances in multiple research fields are required to broaden its potential applications. Photoaging is caused by continuous exposure to ultraviolet (UV) radiation from sunlight. UV radiation generates reactive oxygen species and destroys collagen in the skin, thickening the epidermis, reducing elasticity, and causing wrinkles. We hypothesized that canola meal extract (CME) can mitigate the damage to skin associated with wrinkles induced by exposure to UVB radiation. To evaluate the anti-wrinkle effect, we administered CME orally to 40 female Hos:HR-1 hairless mice divided into 5 groups: (1) control mice, (2) a UVB group, and (3−5) CME-treated groups (CME−250, 500, and 1000 mg/kg body weight/day, respectively). All groups except the controls were irradiated with UVB 3 times a week to create wrinkles due to photoaging. CME administration inhibited the increase of the number, mean length, and mean depth of wrinkles induced by UVB radiation as assessed using a skin replica. Histopathological image analysis revealed that CME administration resulted in a decrease in epidermal thickness and an increase in collagen content, while increasing catalase activity and hydroxyproline content in skin tissues. CME administration inhibited the phosphorylation of mitogen-activated protein kinase and decreased the production of collagenase and gelatinase. These results suggest that CME, an upcycled material, has the potential to develop into a healthful and functional food ingredient with anti-wrinkling effects.</div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141412030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suboptimal diet quality is associated with the incidence of type 2 diabetes mellitus in middle-aged and older populations in China: evidence from a population-based cross-sectional study 中国中老年人群的次优饮食质量与 2 型糖尿病发病率相关：基于人群的横断面研究证据

IF 3.4 3区医学

Nutrition Research Pub Date : 2024-07-01 DOI: 10.1016/j.nutres.2024.05.008

Xiaojun Ma , Pengfei Li , Yu Liu , Lu Liu , Jingjing Xu , Xixiang Wang , Shaobo Zhou , Xiuwen Ren , Ying Wang , Linhong Yuan

{"title":"Suboptimal diet quality is associated with the incidence of type 2 diabetes mellitus in middle-aged and older populations in China: evidence from a population-based cross-sectional study","authors":"Xiaojun Ma , Pengfei Li , Yu Liu , Lu Liu , Jingjing Xu , Xixiang Wang , Shaobo Zhou , Xiuwen Ren , Ying Wang , Linhong Yuan","doi":"10.1016/j.nutres.2024.05.008","DOIUrl":"10.1016/j.nutres.2024.05.008","url":null,"abstract":"<div>The association between dietary quality and type 2 diabetes mellitus (T2DM) based on the Chinese Dietary Balance Index (DBI-16) is seldom reported. We hypothesized that poor dietary quality might increase the risk of T2DM in the middle-aged and older populations. A total of 1816 individuals (≥50 years) were included in the study. Demographic characteristics and dietary intake data were collected. Logistic regression and restricted cubic spline (RCS) analyses were conducted to explore the association between DBI-16 indexes and the risk of T2DM. The insufficient intake of vegetables and dairy might decrease the risk of T2DM (ORVegetable = 0.77, 95% CI = 0.60-0.97; ORDairy = 0.58, 95% CI = 0.35-0.96), but the individuals with insufficient intake of fruit were more likely to have a higher risk of T2DM (ORfruit = 2.26, 95% CI = 1.69-3.06). Compared with the subjects with the lowest quartile of Low Bound Score (LBS) or Diet Quality Distance (DQD), the individuals with Q2 and Q3 level of LBS (ORQ2 = 1.40, 95% CI = 1.03-1.90, P = .033; ORQ3 = 1.52, 95% CI = 1.11-2.08, P < .01) or DQD (ORQ2 = 1.45, 95% CI = 1.06-1.99, P = .021; ORQ3 = 1.64, 95% CI = 1.20-2.24, P < .01) showed increased risk of T2DM with a nonlinear association observed by RCS analysis. We concluded that imbalanced dietary intake, especially insufficient daily fruit intake, might predict an increased risk of T2DM in the middle-aged and elderly Chinese.</div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141275320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eating behavior and dietary practices are associated with age, sex, body mass index, and body fat in individuals with type 2 diabetes and/or hypertension in Brazil 巴西 2 型糖尿病和/或高血压患者的饮食行为和饮食习惯与年龄、性别、体重指数和体脂的关系

IF 3.4 3区医学

Nutrition Research Pub Date : 2024-06-27 DOI: 10.1016/j.nutres.2024.06.007

{"title":"Eating behavior and dietary practices are associated with age, sex, body mass index, and body fat in individuals with type 2 diabetes and/or hypertension in Brazil","authors":"","doi":"10.1016/j.nutres.2024.06.007","DOIUrl":"10.1016/j.nutres.2024.06.007","url":null,"abstract":"<div>Type 2 diabetes (T2DM), hypertension, and obesity are major contributors to global mortality. This study aimed to evaluate eating behavior and dietary practices among individuals with T2DM and/or hypertension, examining their associations with sociodemographic and anthropometric characteristics. We hypothesized that these factors may contribute to body mass index (BMI) and body fat (BF) levels in these individuals. In a cross-sectional study, adults/older individuals diagnosed with T2DM and/or hypertension were included. Eating behavior was evaluated via Three-factor Eating Questionnaire-R21. Dietary practices were assessed using the Dietary Guidelines for the Brazilian Population (DGBP) questionnaire. Poisson regression examined associations between eating behaviors, dietary practices, and sociodemographic factors. Linear regressions were employed to analyze relationships between eating behavior, dietary practices, BMI, and BF. The study included 275 primarily female (70.5%) participants under 60 years old (54.2%). Male and older participants had a lower prevalence of high scores in the 'emotional eating' (EE; PR: 0.40 [0.25;0.63]) and 'uncontrolled eating' (UE; PR: 0.68 [0.50;0.92]) domains. In contrast, older patients had a higher prevalence of adherence to the DGBP recommendations (PR:1.53 [1.20;1.94]). A positive association was observed between high EE (β:3.71 [1.98;5.44]) and UE (β:2.85 [1.15;4.55]) scores and BMI, whereas higher dietary practice scores (β:-2.19 [-3.88;-0.50]) were negatively associated with BMI. High EE (β:2.20 [0.38;4.02]) and UE (β:1.92 [0.17;3.67]) scores were positively associated with BF regardless of the confounding factors included. Higher scores on the dietary practices were inversely associated with BF (β:-1.94 [-3.67;-0.21]). Understanding dietary behaviors and practices can facilitate a more comprehensive and effective treatment approach.</div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141732378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitamin D supplementation does not alter inflammatory markers in overweight and obese individuals: A systematic review and meta-analysis of randomized controlled trials 补充维生素 D 不会改变超重和肥胖者的炎症指标：随机对照试验的系统回顾和荟萃分析。

IF 3.4 3区医学

Nutrition Research Pub Date : 2024-06-17 DOI: 10.1016/j.nutres.2024.06.005

Henrique José Cavalcanti Bezerra Gouveia , Márcia Maria da Silva , Raul Manhães de Castro , Luan Kelwyny Thaywã Marques da Silva , Caio Matheus Santos da Silva Calado , Eulália Rebeca da Silva Araújo , Mariana de Almeida Cruz Silva , Ana Elisa Toscano

{"title":"Vitamin D supplementation does not alter inflammatory markers in overweight and obese individuals: A systematic review and meta-analysis of randomized controlled trials","authors":"Henrique José Cavalcanti Bezerra Gouveia , Márcia Maria da Silva , Raul Manhães de Castro , Luan Kelwyny Thaywã Marques da Silva , Caio Matheus Santos da Silva Calado , Eulália Rebeca da Silva Araújo , Mariana de Almeida Cruz Silva , Ana Elisa Toscano","doi":"10.1016/j.nutres.2024.06.005","DOIUrl":"10.1016/j.nutres.2024.06.005","url":null,"abstract":"<div>Chronic low-grade inflammation is a common feature of obesity and plays a crucial role in the progression of its complications. Vitamin D (VitD) plays an important role in modulating the immune response and regulating inflammation. Thus, this systematic review and meta-analysis aimed to evaluate the effects of isolated VitD supplementation on main inflammatory markers in overweight and obese individuals with no comorbidities and with VitD deficiency. We hypothesized that the increase in serum VitD concentrations after supplementation would significantly reduce the concentrations of inflammatory markers. The search was conducted in Medline/PubMed, SCOPUS, EMBASE, and Web of Science. Eleven randomized placebo-controlled studies were included in the final analysis, with a total of 504 participants and daily (1000-7000 international units) or bolus (100,000-200,000 international units) doses of VitD lasting from 2 to 26 weeks. The VitD supplementation did not influence C-reactive protein (mean difference [MD]: 0.01; 95% confidence interval [CI] –0.37, 0.39; P = .97), interleukin-6 (MD: –0.34; 95% CI –1.09, 0.42; P = .38), and tumor necrosis factor concentrations (MD: –0.02; 95% CI –0.23, 0.19; P = .85). In the analysis considering the studies with a significant increase in serum VitD concentrations, VitD supplementation also did not influence C-reactive protein (MD: –0.17; 95% CI –0.88, 0.54; P = .64), interleukin-6 (MD: –0.47; 95% CI –1.31, 0.37; P = .27), and tumor necrosis factor concentrations (MD: 0.01; 95% CI –1.34, 1.37; P = .98). This meta-analysis suggests that VitD supplementation does not significantly alter inflammatory markers in overweight and obese individuals.</div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141603980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relative validity of nutrition assessment methods for estimating infant carotenoid intake differs by assessment tool, nutrient database, and milk carotenoid adjustment method 估算婴儿类胡萝卜素摄入量的营养评估方法的相对有效性因评估工具、营养素数据库和牛奶类胡萝卜素调整方法而异

IF 3.4 3区医学

Nutrition Research Pub Date : 2024-06-13 DOI: 10.1016/j.nutres.2024.06.003

{"title":"The relative validity of nutrition assessment methods for estimating infant carotenoid intake differs by assessment tool, nutrient database, and milk carotenoid adjustment method","authors":"","doi":"10.1016/j.nutres.2024.06.003","DOIUrl":"10.1016/j.nutres.2024.06.003","url":null,"abstract":"<div>Validated carotenoid assessment methods are needed to study infant carotenoid nutrition. This is a secondary analysis of repeated diet assessments of healthy participants collected at 4- (n = 21), 6- (n = 12), and 8- (n = 9) months of age in Houston, TX between April 2019 and June 2020. Intake was assessed with 3 assessment tools, analyzed with 3 nutrient databases, and underwent 3 adjustments to account for milk composition variability. We hypothesized that manual adjustment of milk carotenoid intake based on laboratory measurements would improve the validity of all assessment approaches and that using a database with greater coverage of infant food carotenoid compositions would improve accuracy. Generalized linear mixed models assessed associations between tool, nutrient database, age, and milk carotenoid adjustment variables with carotenoid, energy, fruit, and vegetable intakes. The effect of the number of food diary days on intake estimate precision was evaluated by testing the correlation between intake estimates derived from 1, 3, or 5, vs. 7 days. Visit age influenced energy intake estimates (p = .029), along with assessment tool (p = .020). Estimates of vegetable intake were influenced by tool (p = .009). Combined fruit and vegetable intake differed by nutrient database (p = .007). Carotenoid intake differed by age (p =<.0001), tool (p = .002), and nutrient database (p = .004). A minimum of 3 food diary days strongly correlated (rho = 0.79-1) with reference estimates across ages. Milk carotenoid adjustment was most influential in estimating 4-month olds’ carotenoid intake, while nutrient database and tool were important for 6- and 8-month-olds’, highlighting the dynamic nature of infant diet assessment validity across feeding stages.</div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141391482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guava leaf extract attenuated muscle proteolysis in dexamethasone induced muscle atrophic mice via ubiquitin proteasome system, mTOR-autophagy, and apoptosis pathway 番石榴叶提取物通过泛素蛋白酶体系统、mTOR-自噬和细胞凋亡途径减轻地塞米松诱导的肌肉萎缩小鼠的肌肉蛋白溶解作用

IF 3.4 3区医学

Nutrition Research Pub Date : 2024-06-04 DOI: 10.1016/j.nutres.2024.05.009

Heaji Lee , Yunju Eo , Sun Yeou Kim , Yunsook Lim

{"title":"Guava leaf extract attenuated muscle proteolysis in dexamethasone induced muscle atrophic mice via ubiquitin proteasome system, mTOR-autophagy, and apoptosis pathway","authors":"Heaji Lee , Yunju Eo , Sun Yeou Kim , Yunsook Lim","doi":"10.1016/j.nutres.2024.05.009","DOIUrl":"10.1016/j.nutres.2024.05.009","url":null,"abstract":"<div>Muscle atrophy is the waste or loss of muscle mass and is caused by physical inactivity, aging, or diseases such as diabetes, cancer, and heart failure. The number of patients suffering from musculoskeletal disorders is expected to increase in the future. However, intervention for muscle atrophy is limited, so research on treatment for muscle wasting is needed. This study hypothesized that guava leaf (Psidium guajava L. [GL]) would have ameliorative effects on muscle atrophy by regulation of protein degradation pathways in a dexamethasone (DEX)-induced muscle atrophy mice model. Muscle atrophy was induced by DEX injection for 28 days in 7 week-old-male ICR mice. Then, low-dose GL (LGL, 200 mg/kg) or high-dose GL (HGL, 500 mg/kg) extract (GLE) was supplemented by oral gavage for 21 days. Muscle strength, calf thickness, and body composition were analyzed. Histopathological changes in the gastrocnemius muscle were examined using hematoxylin and eosin staining, and molecular pathways related to muscle degradation were analyzed by western blots. GLE treatment regardless of dose increased muscle strength in mice with muscle atrophy accompanied by attenuating autophagy related pathway in the DEX-induced muscle atrophy mice. Moreover, a high dose of GLE treatment ameliorated ubiquitin proteasome system and apoptosis in the DEX-induced muscle atrophy mice. This study suggested that GLE could be helpful to improve muscle health and alleviate proteolysis by regulation of the ubiquitin–proteasome system, autophagy, and apoptosis, which are involved in muscle degradation. In conclusion, GLE could be a potential nutraceutical to prevent muscle atrophy.</div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141281636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial office and Board Members 编辑部和董事会成员

IF 4.5 3区医学

Nutrition Research Pub Date : 2024-06-01 DOI: 10.1016/S0271-5317(24)00082-4

引用次数: 0

David Kritchevsky Graduate Student Award for Nutrition Research 大卫-克里切夫斯基营养研究研究生奖

IF 4.5 3区医学

Nutrition Research Pub Date : 2024-06-01 DOI: 10.1016/S0271-5317(24)00083-6

引用次数: 0