Nutrition Research最新文献

{"title":"A response to a letter to the editor: \"Claims of group-level accuracy for bioelectrical impedance analysis in paediatric obesity: A cautionary note\".","authors":"Camilla Raaby Benjaminsen, Rasmus Møller Jørgensen, Esben Thyssen Vestergaard, Jens Meldgaard Bruun","doi":"10.1016/j.nutres.2025.07.004","DOIUrl":"https://doi.org/10.1016/j.nutres.2025.07.004","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144765106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mindful eating intervention for preventing obesity in youth: A narrative review of literature","authors":"Tamara Gutiérrez-Domingo ,&nbsp;Sebastián Vivas","doi":"10.1016/j.nutres.2025.07.001","DOIUrl":"10.1016/j.nutres.2025.07.001","url":null,"abstract":"<div><div>Obesity is a chronic multifactorial disease with associated harms and risks to health, as well as to quality of life and well-being. Currently, approximately 8% of the child and adolescent population suffer from obesity. The objective was to review psychoeducational interventions based on mindful eating for the prevention and management of obesity in youth. A review of the literature was conducted following a narrative approach with a review of different sources. Several databases were consulted (Web of Science [all databases], PsycINFO, Scopus). After searching for psychoeducational interventions based on mindful eating, a total of 15 articles were found, of which 10 were of a preventive nature in the normative child-adolescent population and the rest were aimed at the overweight or obese population or both conditions. The programs that trained mindful eating found behavioral improvements such as an increase in the choice and self-control in the consumption of food, in the identification of biological sensations, improvement in self-concept and well-being. In those interventions aimed at young people with obesity, improvements were obtained in aspects related to mindful eating, self-efficacy in weight control and food-related cravings, and in food control and the regulation of associated emotions. However, a great variety of weaknesses have been detected in the programs, such as the heterogeneity of applied models, use of measures, duration, sample size, lack of protocolization, control groups, or follow-up measures, among others. In conclusion, future lines of mindful eating-based interventions are proposed to extend the results by overcoming the limitations of the studies reviewed.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"140 ","pages":"Pages 116-134"},"PeriodicalIF":3.4,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin E is associated with inflammatory biomarkers and metabolic syndrome: insights from a population study","authors":"Marcela Larissa Costa ,&nbsp;Cristiane Hermes Sales ,&nbsp;João Valentini Neto ,&nbsp;Flávia Mori Sarti ,&nbsp;Marcelo Macedo Rogero ,&nbsp;Regina Mara Fisberg","doi":"10.1016/j.nutres.2025.06.009","DOIUrl":"10.1016/j.nutres.2025.06.009","url":null,"abstract":"<div><div>Vitamin E is a potent antioxidant with anti-inflammatory properties and has been proposed as a promising agent in mitigating conditions associated with metabolic syndrome (MetS). We hypothesize that vitamin E is inversely associated with inflammatory biomarkers and low-grade systemic inflammation while showing a direct association with anti-inflammatory biomarkers. Additionally, we hypothesize that vitamin E will also be inversely associated with the risk of developing MetS. This population-based, cross-sectional study used data from the 2015 ISA-Nutrition survey, which included 368 adults and 212 older adults residing in urban São Paulo. Plasma vitamin E concentration was measured using high-performance liquid chromatography, and MetS was diagnosed based on International Diabetes Federation criteria. Biochemical and anthropometric parameters were assessed using standardized protocols. Restricted cubic spline regression models were applied to evaluate nonlinear associations between vitamin E, inflammation, and MetS. In the linear association between IL-6 and vitamin E, there is an interaction with HDL-c. Our findings also revealed a nonlinear J-shaped association between vitamin E and hepcidin (<em>P</em> &lt; .0001), IL-1β (<em>P</em> &lt; .0001), and adiponectin (<em>P</em> &lt; .001), as well as an inverse association with low-grade systemic inflammation (<em>P</em> &lt; .05). Additionally, vitamin E demonstrated a nonlinear association with MetS (<em>P</em> &lt; .01). These results suggest that vitamin E may play a protective role in modulating inflammation and MetS within this specific urban population. Understanding the interactions between vitamin E, inflammation, and MetS risk is essential for developing prevention and dietary management strategies. Future research should explore the underlying mechanisms and assess optimal vitamin E intake to support metabolic health.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"140 ","pages":"Pages 161-172"},"PeriodicalIF":3.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating biological age, epigenetic clocks, and telomere length in precision nutrition strategies for chronic disease management: Potential frameworks and ongoing challenges","authors":"Beatriz G. Carvalho ,&nbsp;Amanda A. Ribeiro ,&nbsp;Jhulia C.N.L. da Mota ,&nbsp;Lucas M. Carvalho ,&nbsp;Carolina F. Nicoletti","doi":"10.1016/j.nutres.2025.06.010","DOIUrl":"10.1016/j.nutres.2025.06.010","url":null,"abstract":"<div><div>Precision nutrition is emerging as a transformative strategy for optimizing health, particularly in the context of biological aging and chronic disease prevention. This review aims to examine how biological age markers—specifically telomere length and epigenetic clocks—can be integrated into precision nutrition frameworks to personalize interventions, enhance chronic disease management, and support healthy aging. Telomere length is a widely studied biomarker of aging and chronic disease risk, while epigenetic clocks, based on DNA methylation patterns, offer complementary insights into biological age, gene expression, and disease susceptibility. Nutritional interventions rich in antioxidants, omega-3 fatty acids, polyphenols, B vitamins, and anti-inflammatory compounds have shown potential to modulate these biomarkers, supporting cellular health and delaying aging processes. In addition, lifestyle factors such as physical activity, stress management, and adequate sleep play critical roles in maintaining telomere integrity and epigenetic stability. However, challenges remain in translating these biomarkers into clinical practice. Importantly, variability is not the only barrier; most of these biomarkers still lack clinical validation, and there is no consensus on standardized protocols or reference values that would support their routine application in healthcare<strong>.</strong> Current guidelines recommend combining telomere length and epigenetic age with other molecular markers, such as multi-omics data, within integrative biological age assessment approaches. Nevertheless, translating this approach into clinical practice will require overcoming significant limitations, including the validation of biomarkers, standardization of measurement techniques, cost-effectiveness, and the development of clear clinical guidelines. Continued research is essential to confirm their predictive value and practical utility in precision nutrition strategies aimed at promoting healthy aging and preventing chronic diseases.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"140 ","pages":"Pages 135-160"},"PeriodicalIF":3.4,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotional and uncontrolled eating behaviors are associated with poorer glycemic control in patients with type 2 diabetes","authors":"Ana Carolina Freitag ,&nbsp;Olívia Garbin Koller ,&nbsp;Vanessa Machado Menezes ,&nbsp;Vivian Cristine Luft ,&nbsp;Jussara Carnevale de Almeida","doi":"10.1016/j.nutres.2025.06.006","DOIUrl":"10.1016/j.nutres.2025.06.006","url":null,"abstract":"<div><div>Type 2 diabetes mellitus (T2DM) is a prevalent and multifactorial disease closely linked to overweight. Positive associations between body mass index (BMI) and dysfunctional eating behavior have been observed. However, research specifically examining eating behaviors among individuals with T2DM remains limited. We hypothesized that disordered eating behavior in this population is associated with poorer metabolic control. Thus, this study aimed to investigate the relationship between eating behavior patterns and metabolic control in outpatients with T2DM. In this cross-sectional study, the Three Factor Eating Questionnaire (TFEQ-R21) was administered to 238 outpatients with T2DM. BMI, glycemic control, blood lipids concentration, and blood pressure were examined as outcomes. Eating behavior patterns were identified through cluster analysis based on TFEQ-R21 dimensions. Linear regression models were used to investigate the associations between eating behavior patterns and outcomes, adjusting for age, sex, sedentary lifestyle, and psychiatric medication use. The study was approved by the Hospital's Ethics Committee (ID 2020-0654). Two eating behavior patterns were identified: <em>cognitive restraint</em> (<em>n</em> = 174) and <em>emotional and uncontrolled eating behavior</em> (<em>n</em> = 64). The <em>emotional and uncontrolled eating behavior</em> pattern was associated with higher BMI (b = 2.35; 95% CI = 0.68-4.01), HbA1c (b = 0.54; 95% CI = 0.06-1.01), and triglyceride values (b = 64.42; 95% CI = 16.99-111.86) after adjusting for confounders. In this sample of outpatients with T2DM, the <em>emotional and uncontrolled eating behavior</em> pattern was associated with higher BMI, HbA1c, and triglyceride values as compared to the <em>cognitive restraint eating behavior</em> pattern<em>.</em></div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"140 ","pages":"Pages 93-101"},"PeriodicalIF":3.4,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional hypothalamic amenorrhea and dietary intervention: A systematic review to guide further research in amenorrheic women without overt eating disorder","authors":"Anna Paola Amoroso ,&nbsp;Simona Fiorini ,&nbsp;Lenycia de Cassya Lopes Neri ,&nbsp;Monica Guglielmetti ,&nbsp;Anna Tagliabue ,&nbsp;Rossella Elena Nappi ,&nbsp;Cinzia Ferraris","doi":"10.1016/j.nutres.2025.06.008","DOIUrl":"10.1016/j.nutres.2025.06.008","url":null,"abstract":"<div><div>Functional hypothalamic amenorrhea (FHA) is a multifactorial condition caused by psychological stress, energy deficit, weight loss, and excessive physical activity in the absence of adequate energy intake. Nutrition plays a key role in FHA treatment, with the primary intervention focused on correcting energy imbalance. Evidence regarding the exact amount of energy required to restore menses, the timeframe for recovery, and the optimal nutritional practices to support long-term recovery and optimize reproductive outcomes, remain limited. In this review, we aimed to assess if dietary intervention affects the nutritional status, food intake, nutrition knowledge, and hormonal milieu in women with FHA. We performed this review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method, using the Population, Intervention, Control, Outcome, Study design criteria. A quality appraisal checklist for case series was used. The search included 4 databases and was restricted to English and Italian languages. Eleven articles were included. Five of these referred to the same population analyzed in 2 randomized controlled trials (RCTs); 3 nonrandomized controlled trials (NRCTs); and 1 nonrandomized uncontrolled trial, and 2 case series. Overall, the risk of bias was low for RCTs and moderate-to-high for NRCTs. Menstrual cycle can be restored in 1 to 12 months. One article indicated an additional 350 kcal/d energy intake to achieve this. However, the long-term impact of nutritional intervention alone remains unclear. Further research with a comprehensive, patient-centered approach is needed to confirm these findings and to clarify the possible role of nutritional counseling in FHA treatment.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"140 ","pages":"Pages 102-115"},"PeriodicalIF":3.4,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"David Kritchevsky Graduate Student Award for Nutrition Research","authors":"","doi":"10.1016/S0271-5317(25)00083-1","DOIUrl":"10.1016/S0271-5317(25)00083-1","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"139 ","pages":"Page iii"},"PeriodicalIF":3.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144366594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasma advanced glycation products are associated with increased risk of depression in middle-aged and elderly Chinese adults","authors":"Yebing Zhang ,&nbsp;Yu Zhang ,&nbsp;Fengfei Xie ,&nbsp;Nimei Zeng ,&nbsp;Renfang Han ,&nbsp;Yun Wang ,&nbsp;Zhongxiao Wan","doi":"10.1016/j.nutres.2025.06.004","DOIUrl":"10.1016/j.nutres.2025.06.004","url":null,"abstract":"<div><div>Depression is becoming a critical health challenge for the middle-aged and elderly populations. Existing evidence on the associations between body accumulations of advanced glycation end products (AGEs) and depression remain inconsistent. We hypothesized that plasma AGEs concentration might be positively correlated with the incidence of depression in middle-aged and elderly adults. In this cross-sectional study with 586 participants (201 males and 385 females, mean age: 62.18 years old) from Suzhou city, depression was assessed via the Center for Epidemiologic Studies Depression scale 10-item version (CES-D-10). Plasma AGEs of free Nε-carboxymethyl-L-lysine (CML), Nε-(1-carboxyethyl) lysine (CEL), and Nδ-(5-hydro-5-methyl-4-imidazolon-2-yl)-ornithine (MG-H1), as well as protein bound CEL and CML were measured with ultraperformance liquid chromatography and tandem mass spectrometry. Multivariate linear regression analysis and logistic regression analysis were utilized to determine the associations between specific plasma AGEs and CES-D-10 score and the incidence of depression, respectively. The incidence of depression was 8.02%. Plasma protein bound CEL and CML concentration were positively correlated with CES-D-10 score (CEL: β=0.12, <em>P</em>=0.018; CML: β=0.14; <em>P</em>=0.034) in the linear regression analysis. Compared to those below the median concentration of bound CEL and CML, participants with bound CEL and CML concentration above the median had increased risk of depression [ORs (95% CI): 2.33 (1.13-4.84), <em>P</em>=0.023, and ORs (95% CI): 2.27 (1.16-4.43), <em>P</em>=0.016, respectively] in the logistic regression analysis. Elevated plasma bound CEL and CML might be associated with increased risk of depression. Further studies are required to confirm the associations between specific AGEs and the risk of depression.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"140 ","pages":"Pages 59-68"},"PeriodicalIF":3.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial office and Board Members","authors":"","doi":"10.1016/S0271-5317(25)00082-X","DOIUrl":"10.1016/S0271-5317(25)00082-X","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"139 ","pages":"Pages i-ii"},"PeriodicalIF":3.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144366593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sweetened beverage intake across moderate intake range is not associated with pregnancy-related weight change or biomarkers of glycemic control","authors":"Mia G. Kwan ,&nbsp;Leah M. Lipsky ,&nbsp;Kyle S. Burger ,&nbsp;Grace E. Shearrer ,&nbsp;Tonja R. Nansel","doi":"10.1016/j.nutres.2025.06.007","DOIUrl":"10.1016/j.nutres.2025.06.007","url":null,"abstract":"<div><div>While sweetened beverage intake is associated with weight and glycemic outcomes in the general population, relations during pregnancy are unclear. This prospective observational study tested the hypothesis that greater sweetened beverage intake would be associated with higher pregnancy-related weight change and glucose regulation biomarkers. The Pregnancy Eating Attributes Study recruited participants with uncomplicated singleton pregnancies ≤12 weeks gestation and no major chronic illness from 2 obstetrics clinics in the University of North Carolina at Chapel Hill Healthcare System from November 2014 to October 2016. Data from participants with completed pregnancy dietary recalls (n = 365) were analyzed. Intake (oz) of sugar-sweetened beverages (SSB) and non-nutritive sweetened beverages (NNSB) was calculated from 24-h dietary recalls across pregnancy and across postpartum. Weight was measured throughout pregnancy to 1-year postpartum to determine gestational weight gain adequacy and 1-year postpartum weight retention; fasting blood glucose and insulin were obtained in the 2nd trimester. Multinomial logistic regressions estimated associations of sweetened beverage intake with gestational weight gain adequacy; linear regressions estimated associations of sweetened beverage intake with postpartum weight retention, fasting blood glucose, and insulin. In analyses adjusted for age, household income-poverty ratio, education, marital status, and physical activity, neither SSB nor NNSB intake during pregnancy was associated with excessive gestational weight gain, postpartum weight retention, fasting glucose or fasting insulin. Additionally, SSB and NNSB intake in postpartum were unassociated with postpartum weight retention. Sweetened beverages may not contribute to excess pregnancy-related weight gain or glucose dysregulation within the moderate range of intake observed in this sample.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"140 ","pages":"Pages 69-76"},"PeriodicalIF":3.4,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}