Hang Zhang , Li Li , Yuwei Wang , Yuhan Xie , Bing Chen
{"title":"在美国成年人中,适量摄入类胡萝卜素可以预防肌肉减少性肥胖:一项横断面研究","authors":"Hang Zhang , Li Li , Yuwei Wang , Yuhan Xie , Bing Chen","doi":"10.1016/j.nutres.2025.09.002","DOIUrl":null,"url":null,"abstract":"<div><div>Carotenoids have been recognized for their potential health benefits due to their potent anti-inflammatory and antioxidant properties. However, evidence regarding the specific relationship between carotenoid intake and sarcopenic obesity (SO) remains limited. We hypothesized that moderate carotenoid intake was associated with a lower SO risk. A cross-sectional study was conducted involving 10,060 adults aged 18 to 59 from the National Health and Nutrition Examination Survey 2011-2018. Whole-body composition was assessed by dual-energy X-ray absorptiometry, while carotenoid intake was obtained through two 24-hour dietary recall interviews. Weighted logistic regression models, stratified analyses, restricted cubic spline analyses, and sensitivity analyses were utilized for this study. The weighted prevalence of SO was 7.51%. Weighted logistic regression revealed that dietary α-carotene, β-carotene, and β-cryptoxanthin intake was inversely associated with SO risk after accounting for various variables. Age-stratified analyses revealed a significant inverse association between α-carotene intake and SO risk among adults aged 40 to 59, whereas β-carotene and β-cryptoxanthin exhibited similar inverse relationships in the 18 to 39 age group. The sex-stratified analysis demonstrated that the highest tertile of α-carotene, β-carotene, and β-cryptoxanthin intake was inversely correlated with the risk of SO among females. Restricted cubic spline regression analysis revealed a U-shaped association between dietary intake of α-carotene, β-carotene, and β-cryptoxanthin with SO risk, particularly in 40-59-year-olds and females. In conclusion, moderate dietary α-carotene (0.77 mg/day), β-carotene (3.93 mg/day), and β-cryptoxanthin (0.19 mg/day) consumption was associated with a lower SO risk. The relationship between these carotenoids and SO was nonlinear, particularly among individuals aged 40 to 59 years and in females.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"142 ","pages":"Pages 46-62"},"PeriodicalIF":3.1000,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Moderate carotenoid intakes protect against sarcopenic obesity among U.S. adults: A cross-sectional study\",\"authors\":\"Hang Zhang , Li Li , Yuwei Wang , Yuhan Xie , Bing Chen\",\"doi\":\"10.1016/j.nutres.2025.09.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Carotenoids have been recognized for their potential health benefits due to their potent anti-inflammatory and antioxidant properties. However, evidence regarding the specific relationship between carotenoid intake and sarcopenic obesity (SO) remains limited. We hypothesized that moderate carotenoid intake was associated with a lower SO risk. A cross-sectional study was conducted involving 10,060 adults aged 18 to 59 from the National Health and Nutrition Examination Survey 2011-2018. Whole-body composition was assessed by dual-energy X-ray absorptiometry, while carotenoid intake was obtained through two 24-hour dietary recall interviews. Weighted logistic regression models, stratified analyses, restricted cubic spline analyses, and sensitivity analyses were utilized for this study. The weighted prevalence of SO was 7.51%. Weighted logistic regression revealed that dietary α-carotene, β-carotene, and β-cryptoxanthin intake was inversely associated with SO risk after accounting for various variables. Age-stratified analyses revealed a significant inverse association between α-carotene intake and SO risk among adults aged 40 to 59, whereas β-carotene and β-cryptoxanthin exhibited similar inverse relationships in the 18 to 39 age group. The sex-stratified analysis demonstrated that the highest tertile of α-carotene, β-carotene, and β-cryptoxanthin intake was inversely correlated with the risk of SO among females. Restricted cubic spline regression analysis revealed a U-shaped association between dietary intake of α-carotene, β-carotene, and β-cryptoxanthin with SO risk, particularly in 40-59-year-olds and females. In conclusion, moderate dietary α-carotene (0.77 mg/day), β-carotene (3.93 mg/day), and β-cryptoxanthin (0.19 mg/day) consumption was associated with a lower SO risk. The relationship between these carotenoids and SO was nonlinear, particularly among individuals aged 40 to 59 years and in females.</div></div>\",\"PeriodicalId\":19245,\"journal\":{\"name\":\"Nutrition Research\",\"volume\":\"142 \",\"pages\":\"Pages 46-62\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-09-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nutrition Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0271531725001113\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"NUTRITION & DIETETICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutrition Research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0271531725001113","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
Moderate carotenoid intakes protect against sarcopenic obesity among U.S. adults: A cross-sectional study
Carotenoids have been recognized for their potential health benefits due to their potent anti-inflammatory and antioxidant properties. However, evidence regarding the specific relationship between carotenoid intake and sarcopenic obesity (SO) remains limited. We hypothesized that moderate carotenoid intake was associated with a lower SO risk. A cross-sectional study was conducted involving 10,060 adults aged 18 to 59 from the National Health and Nutrition Examination Survey 2011-2018. Whole-body composition was assessed by dual-energy X-ray absorptiometry, while carotenoid intake was obtained through two 24-hour dietary recall interviews. Weighted logistic regression models, stratified analyses, restricted cubic spline analyses, and sensitivity analyses were utilized for this study. The weighted prevalence of SO was 7.51%. Weighted logistic regression revealed that dietary α-carotene, β-carotene, and β-cryptoxanthin intake was inversely associated with SO risk after accounting for various variables. Age-stratified analyses revealed a significant inverse association between α-carotene intake and SO risk among adults aged 40 to 59, whereas β-carotene and β-cryptoxanthin exhibited similar inverse relationships in the 18 to 39 age group. The sex-stratified analysis demonstrated that the highest tertile of α-carotene, β-carotene, and β-cryptoxanthin intake was inversely correlated with the risk of SO among females. Restricted cubic spline regression analysis revealed a U-shaped association between dietary intake of α-carotene, β-carotene, and β-cryptoxanthin with SO risk, particularly in 40-59-year-olds and females. In conclusion, moderate dietary α-carotene (0.77 mg/day), β-carotene (3.93 mg/day), and β-cryptoxanthin (0.19 mg/day) consumption was associated with a lower SO risk. The relationship between these carotenoids and SO was nonlinear, particularly among individuals aged 40 to 59 years and in females.
期刊介绍:
Nutrition Research publishes original research articles, communications, and reviews on basic and applied nutrition. The mission of Nutrition Research is to serve as the journal for global communication of nutrition and life sciences research on diet and health. The field of nutrition sciences includes, but is not limited to, the study of nutrients during growth, reproduction, aging, health, and disease.
Articles covering basic and applied research on all aspects of nutrition sciences are encouraged, including: nutritional biochemistry and metabolism; metabolomics, nutrient gene interactions; nutrient requirements for health; nutrition and disease; digestion and absorption; nutritional anthropology; epidemiology; the influence of socioeconomic and cultural factors on nutrition of the individual and the community; the impact of nutrient intake on disease response and behavior; the consequences of nutritional deficiency on growth and development, endocrine and nervous systems, and immunity; nutrition and gut microbiota; food intolerance and allergy; nutrient drug interactions; nutrition and aging; nutrition and cancer; obesity; diabetes; and intervention programs.