Nutrition Research最新文献

{"title":"Genetic variants in vitamin D metabolism-related genes are associated with vitamin D status and adiposity markers","authors":"Adriana Becerra‑Cervera ,&nbsp;Rogelio F. Jiménez-Ortega ,&nbsp;Diana I. Aparicio-Bautista ,&nbsp;Tania V. López-Pérez ,&nbsp;Nelly Patiño ,&nbsp;Manuel Castillejos-López ,&nbsp;Alberto Hidalgo‑Bravo ,&nbsp;Edgar Denova‑Gutiérrez ,&nbsp;Jorge Salmerón ,&nbsp;Berenice Rivera‑Paredez ,&nbsp;Rafael Velázquez‑Cruz","doi":"10.1016/j.nutres.2025.02.009","DOIUrl":"10.1016/j.nutres.2025.02.009","url":null,"abstract":"<div><div>Single nucleotide variants (SNVs) in vitamin D (VD) metabolism genes have been shown to be associated with serum 25(OH)D concentrations. Although these associations have been reported in other populations, they are less studied in Mexico, a country with high vitamin D deficiency (VDD) despite ample sun exposure. Therefore, we investigate the association between VD-metabolism related SNVs, serum 25(OH)D concentrations, and their impact on VDD and adiposity indicators. We hypothesized that SNVs are associated with serum 25(OH)D concentrations in the Mexican population. We included 1977 individuals (597 males and 1380 females) from the Health Worker Cohort Study. Nine genetic variants: rs10741657 (<em>CYP2R1</em>), rs6013897 (<em>CYP24A1</em>), rs10877012 (<em>CYP27B1</em>), rs10783219 and rs4516035 (<em>VDR</em>), rs4588 and rs7041 (<em>GC</em>), rs4944957 and rs3794060 (<em>NADSYN1</em>), in VD metabolism-related genes were genotyped. Linear and logistic regression models were used to assess the association of interest. In our study, 7 genetic variants were associated with serum 25(OH)D concentrations and VDD. A genetic risk score was created using variants rs6013897 (<em>CYP24A1</em>), rs4516035 (<em>VDR</em>), and rs4588 (<em>GC</em>), which were associated with lower serum 25(OH)D concentrations, higher VDD prevalence, and increased odds of VDD. A second GRS using all 9 variants showed weaker associations. Gene-gene interactions between rs3794060-rs4944957 (<em>NADSYN1</em>), and rs10877012(<em>CYP27B1</em>)-rs7041(<em>GC</em>), were associated with serum 25(OH)D concentrations and VDD, respectively. Additionally, SNV interactions with body mass index, waist circumference, and body fat distribution were identified. These findings suggest that SNVs influence serum 25(OH)D concentrations and adiposity indicators, with potential clinical implications for obesity management.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"136 ","pages":"Pages 105-119"},"PeriodicalIF":3.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High salt diet causally increases metabolic dysfunction-associated steatotic liver disease risk: A bidirectional mendelian randomization study","authors":"Qi Liu ,&nbsp;Yuyang Liu ,&nbsp;Hui Feng ,&nbsp;Ning Zhang ,&nbsp;Zhanyu Yang","doi":"10.1016/j.nutres.2025.03.004","DOIUrl":"10.1016/j.nutres.2025.03.004","url":null,"abstract":"<div><div>Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent liver disorder associated with metabolic and lifestyle factors, affecting approximately 25% of the global population. Although high salt intake has been implicated as a potential dietary risk factor, its causal relationship with MASLD remains uncertain. We hypothesized that genetic liability to higher salt intake causally increases the risk of MASLD. To address this, bidirectional Mendelian Randomization (MR) analysis was performed to evaluate the causal relationship between “salt added to food” and MASLD. Genetic variants were used as instrumental variables across large-scale genome-wide association study datasets from the UK Biobank and multiple MASLD cohorts. The inverse variance weighting method served as the primary analytical approach, with sensitivity analyses, including MR-Egger and MR-PRESSO, to evaluate pleiotropy and heterogeneity. Forward MR analysis demonstrated a significant association between “salt added to food” and increased MASLD risk across three MASLD datasets: odds ratio (OR) = 1.538, 95% confidence interval (CI): 1.145-2.067, <em>P</em> = .004; OR = 1.787, 95% CI: 1.247-2.561, <em>P</em> = .002; and OR = 2.094, 95% CI: 1.274-3.442, <em>P</em> = .004. Sensitivity analyses indicated low heterogeneity and no evidence of pleiotropy. Reverse MR analysis did not demonstrate a causal effect of MASLD on “salt added to food”. These findings provide robust genetic evidence that “salt added to food” is a causal risk factor for MASLD, emphasizing the importance of dietary salt reduction in MASLD prevention strategies. This study supports public health recommendations advocating reduced salt intake to promote liver health and prevent MASLD.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"136 ","pages":"Pages 94-104"},"PeriodicalIF":3.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial office and Board Members","authors":"","doi":"10.1016/S0271-5317(25)00055-7","DOIUrl":"10.1016/S0271-5317(25)00055-7","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"136 ","pages":"Pages i-ii"},"PeriodicalIF":3.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143808395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"David Kritchevsky Graduate Student Award for Nutrition Research","authors":"","doi":"10.1016/S0271-5317(25)00056-9","DOIUrl":"10.1016/S0271-5317(25)00056-9","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"136 ","pages":"Page iii"},"PeriodicalIF":3.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143808396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probiotic supplementation contributes to glycemic control in adults with type 2 diabetes: A systematic review and network meta-analysis","authors":"Dengrong Ma ,&nbsp;Pingping Zhao ,&nbsp;Jie Gao ,&nbsp;Hui Suo ,&nbsp;Xinyuan Guo ,&nbsp;Mei Han ,&nbsp;Xiaohui Zan ,&nbsp;Chongyang Chen ,&nbsp;Xiaoyu Lyu ,&nbsp;Hui Wang ,&nbsp;Jingfang Liu","doi":"10.1016/j.nutres.2025.03.002","DOIUrl":"10.1016/j.nutres.2025.03.002","url":null,"abstract":"<div><div>Type 2 diabetes mellitus (T2DM) is a chronic medical condition prevalent worldwide. Currently, probiotic therapy has demonstrated favorable outcomes in T2DM management, albeit with a lingering controversy. In this network meta-analysis (NMA), we aimed to assess and rank the glycemic control efficacy of various probiotic strains or combinations in T2DM patients. A systematic literature review was conducted across 4 major databases (PubMed, Embase, Web of Science, and Cochrane Library) including data published up to November 8, 2023, to identify randomized controlled trials (RCTs) on probiotic therapy in T2DM patients. The quality of the included RCTs was evaluated using the risk-of-bias tool version 2, while Bayesian NMA was used for analysis. The efficacy of different probiotics and their combinations was ranked based on the surface under the cumulative ranking curve (SUCRA) for various outcome indicators. This study included 1861 T2DM patients from 30 RCTs. The combination of LAC (<em>Lactobacillus</em>) + BIF (<em>Bifidobacterium</em>) + PRO (<em>Propionibacterium</em>) + STR (<em>Streptococcus</em>) exhibited the most favorable effect in reducing the fasting plasma glucose concentration and improving the homeostatic model assessment of insulin resistance (SUCRA: 88.8% and 77.3%). For reducing the concentration of glycated hemoglobin A1c, BIF (SUCRA: 93.1%) was the most effective; for improving insulin secretion, LAC + BIF (SUCRA: 84.7%) exhibited the most favorable outcome for improving insulin secretion. Cluster analysis of the 4 outcome indicators showed that the LAC + BIF + STR combination may have superior therapeutic effects. Multistrain probiotic combinations demonstrated greater glycemic control effects than single-strain probiotics. Thus, LAC + BIF + STR may be a promising probiotic combination for the treatment of T2DM. Nevertheless, owing to the inherent limitations of existing studies, further research is warranted to ascertain the long-term efficacy of probiotics.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"136 ","pages":"Pages 133-152"},"PeriodicalIF":3.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143776965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intervention design and adherence to Mediterranean diet in the Cardiovascular Risk Prevention with a Mediterranean Dietary Pattern Reduced in Saturated Fat (CADIMED) randomized trial","authors":"Lourdes Chávez-Alfaro ,&nbsp;Carmen Tenorio Jiménez ,&nbsp;Víctor Silveira-Sanguino ,&nbsp;María José Noguera Gómez ,&nbsp;Concepción Fernández-Moreno ,&nbsp;Ana María Rodríguez Cuesta ,&nbsp;Antonio F. Lebrón Arana ,&nbsp;Óscar Segura Calvo ,&nbsp;Ignacio Merino De Haro ,&nbsp;Concepción M. Aguilera ,&nbsp;Carolina Gómez-Llorente ,&nbsp;Óscar Daniel Rangel-Huerta ,&nbsp;Nerys Astbury ,&nbsp;Aurora Pérez-Cornago ,&nbsp;Marta Guasch-Ferre ,&nbsp;Carmen Piernas","doi":"10.1016/j.nutres.2025.03.001","DOIUrl":"10.1016/j.nutres.2025.03.001","url":null,"abstract":"<div><div>Effective interventions targeting modifiable cardiovascular disease (CVD) risk factors, such as diet, are urgently needed. The Cardiovascular Risk Prevention with a Mediterranean Dietary Pattern Reduced in Saturated Fat study hypothesizes that eliminating red and processed meat in the context of a Mediterranean diet (MD) will significantly modify circulating low-density lipoprotein cholesterol concentration and the fatty acid profile compared to general CVD prevention advice. Here we describe the intervention design and summarize baseline dietary intakes (mean ± standard deviation) related to MD adherence and red/processed meat intakes in a sample of 81 participants. The Cardiovascular Risk Prevention with a Mediterranean Dietary Pattern Reduced in Saturated Fat study is a two-arm, 8-week parallel randomized controlled intervention trial involving a final sample of 156 adults (≥18 years) with dyslipidemia (not undergoing pharmacological treatment) recruited from healthcare and community settings in Granada (Spain). The primary outcome will assess changes in circulating low-density lipoprotein cholesterol and the fatty acid profile, whilst secondary outcomes will measure changes in CVD-related metabolites/biomarkers, gut microbiome, diet/lifestyle, and intervention feasibility/acceptability. Preliminary findings indicate low MD adherence (Mediterranean Diet Adherence Screener score 7.6 ± 1.9), and high consumption of red and processed meat (1.04 ± 0.90) servings/d). These results underscore the need for targeted dietary interventions to address the growing burden of dyslipidemia and CVD. If successful, this intervention holds potential for scalability and significant impact on public health, dietary guidelines, and advancements in nutrition science by improving MD adherence and reducing CVD risk factors in adults with dyslipidemia.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"136 ","pages":"Pages 120-132"},"PeriodicalIF":3.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fish consumption is inversely associated with stroke in Korean adults: the Korea National Health and Nutrition Examination Survey, 2013 to 2021","authors":"Eunje Kim,&nbsp;Youjin Je","doi":"10.1016/j.nutres.2025.03.010","DOIUrl":"10.1016/j.nutres.2025.03.010","url":null,"abstract":"<div><div>There is growing evidence supporting a potential role of fish consumption in relation to stroke risk. Several studies have examined the association between fish consumption and stroke risk in various populations, but none have been conducted in Koreans. We hypothesized that there may also be an inverse association between fish consumption and stroke risk in Korean adults. Therefore, we conducted a cross-sectional study using data from the Korea National Health and Nutrition Examination Survey, 2013 to 2021. A total of 30,143 adults aged 19 to 64 years were included in the analysis. Fish consumption was assessed using a 24-hour dietary recall, and the subjects were categorized into four groups based on their total fish consumption (0, 0≤ to &lt;1/2, 1/2≤ to &lt;1, ≥1 serving/d). Stroke status was assessed using questionnaires. Multivariable logistic regression model was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for physician-diagnosed stroke. After adjusting for covariates, high fish consumption was associated with 46% lower odds of stroke in Korean adults compared with no fish consumption (OR 0.54; 95% CI, 0.31-0.94, <em>P</em> for trend = .041). A similar inverse association was found in male adults (OR 0.47; 95% CI, 0.23-0.97, <em>P</em> for trend = .042), and an inverse association between moderate fish consumption and stroke risk was found in female adults (OR 0.22; 95% CI, 0.06-0.78). Our findings suggest that high fish consumption is associated with lower odds of stroke in Korean adults, particularly in men, and moderate fish consumption was associated with lower odds of stroke in women.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"137 ","pages":"Pages 47-55"},"PeriodicalIF":3.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143842830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibitory control is related to fecal short-chain fatty acid concentrations in adults with overweight and obesity","authors":"Nathaniel B. Willis ,&nbsp;Corinne N. Cannavale ,&nbsp;Anne M. Walk ,&nbsp;Nicholas A. Burd ,&nbsp;Hannah D. Holscher ,&nbsp;Naiman A. Khan","doi":"10.1016/j.nutres.2025.03.006","DOIUrl":"10.1016/j.nutres.2025.03.006","url":null,"abstract":"<div><div>Obesity is a pro-inflammatory condition with negative effects on executive functioning. Increased inflammation dysregulates gastrointestinal homeostasis and alters microbiota community composition. The gut microbiota produce immunomodulatory short-chain fatty acids (SCFA) that have been related to cognition in obesity, but the neural effects are not explored. Here, we hypothesized that greater fecal SCFA would be positively related to neuroelectric markers of inhibitory control and conflict monitoring in obesity. A cross-sectional cohort of 87 adults (35 ± 6 years, 53 females) with overweight and obesity (BMI = 32 ± 6 kg/m²) provided fresh fecal samples and participated in cognitive testing to assess response inhibition and conflict monitoring with electroencephalographic recording. Linear regressions, controlling for age, sex, BMI, and energy-adjusted dietary fiber intake, revealed positive relationships between NoGo N2 mean amplitude and fecal SCFA concentrations. Linear discriminant analysis effect size (LEfSe) revealed 16 amplicon sequence variants differentially abundant between high and low butyrate groups with <em>Roseburia</em> and <em>Adlercreutzia</em> individually related to NoGo N2 mean amplitude in MaAsLin2 modeling. Thus, greater fecal SCFA concentrations and SCFA producing microbiota (i.e., <em>Roseburia</em>) were related to markers of superior conflict monitoring in the NoGo task when adjusting for key covariates. These data highlight key associations between bacterial derived gut signaling molecules and neural regulation in cognitive domains particularly relevant to weight status that warrant further investigation.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"138 ","pages":"Pages 12-21"},"PeriodicalIF":3.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher serum vitamin B6 is associated with lower all-cause mortality among cancer survivors in the National Health and Nutrition Examination Survey","authors":"Yutong Zhao,&nbsp;Ruhua Zhou,&nbsp;Fangting Lin,&nbsp;Caixia Zhang","doi":"10.1016/j.nutres.2025.03.011","DOIUrl":"10.1016/j.nutres.2025.03.011","url":null,"abstract":"<div><div>Variations in serum concentrations of vitamin B₆, vitamin B₁₂, and folate may influence cancer development and progression. However, the association between these 3 serum B vitamins and all-cause mortality among cancer survivors remains unclear. We evaluated the potential associations between serum vitamins B₆, B₁₂, and folate and all-cause mortality among cancer survivors. Our hypothesis proposed that higher serum concentrations of vitamin B₆, vitamin B₁₂, and folate might be inversely associated with a lower risk of all-cause mortality in this population. Data from the National Health and Nutrition Examination Survey (NHANES) 1999-2018 were used. All-cause mortality was determined by linking participant data to National Death Index records till 31 December 2019. Serum vitamins B₆, B₁₂, and folate status were measured. Multivariable Cox regression analyses were applied to investigate the relationship between serum vitamins B₆, B₁₂, and folate concentrations and all-cause mortality among cancer survivors. Serum vitamin B₆ was inversely associated with all-cause mortality, with a fully-adjusted HR of 0.54 (95%CI: 0.38, 0.78, <em>P</em> _trend&lt; .001). However, no statistically significant association was observed between serum vitamin B₁₂ as well as serum folate concentration and all-cause mortality among cancer survivors (B₁₂: fully-adjust HR = 0.90, 95%CI: 0.63, 1.27, <em>P</em> _trend = .771; folate: fully-adjust HR = 0.82, 95%CI: 0.63, 1.08, <em>P</em> _trend = .269). No statistically significant interaction for age, sex, and BMI was found in stratified analyses. No non-linear relationship was found except for serum folate. These results suggest that higher serum vitamin B₆ may be associated with improved survival in cancer survivors.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"138 ","pages":"Pages 1-11"},"PeriodicalIF":3.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the effectiveness of calorie restriction with and without time-restricted eating on the circadian regulation of metabolism: rationale and protocol of a three-arm randomised controlled trial in adults at risk of type 2 diabetes","authors":"You Jin Chang ,&nbsp;Laurent Turner ,&nbsp;Xiao Tong Teong ,&nbsp;Lijun Zhao ,&nbsp;Athena Variji ,&nbsp;Gary A. Wittert ,&nbsp;Sophia Thompkins ,&nbsp;Andrew D. Vincent ,&nbsp;Linda Grosser ,&nbsp;Morag J. Young ,&nbsp;Stephen Blake ,&nbsp;Satchidananda Panda ,&nbsp;Emily N.C. Manoogian ,&nbsp;Siobhan Banks ,&nbsp;Leonie K. Heilbronn ,&nbsp;Amy T. Hutchison","doi":"10.1016/j.nutres.2025.03.009","DOIUrl":"10.1016/j.nutres.2025.03.009","url":null,"abstract":"<div><div>Time-restricted eating (TRE) may extend the cardiometabolic health benefits of calorie restriction (CR). However, few studies have compared its effect on the circadian regulation of glucose metabolism and the optimal time of day to initiate TRE is also unclear. This study aims to compare the effectiveness of CR with and without TRE on glucose tolerance in response to 3 identical meals consumed over the day. A parallel, single-blinded, 3-arm randomised controlled trial will be conducted in 114 adults, aged 35 to 75 years with a BMI ≥25.1 but &lt;45.0 kg/m², elevated waist circumference and fasting blood glucose (≥5.6 mmol/L), and who score ≥12 on the Australian Type 2 Diabetes Risk Assessment tool. Participants will be stratified by sex and fasting blood glucose (≤6.0 mmol/L; &gt;6.0 mmol/L) and then randomised (1:1:1) to CR (unrestricted meal timing), eCR (0800 to 1600) or dCR (1200-2000) for 8 weeks. The primary outcome is the change in the natural logarithm of the mean over 3 identical meals of the postprandial glucose area under the curve (AUC). The analysis will be performed using a covariate adjusted linear regression of the differences in postprandial glucose log AUC at 8 weeks from baseline. This randomised clinical trial will be the first to delineate the benefits of CR alone or in combination with time restricted eating on postprandial glucose metabolism over the day in adults at increased risk of type 2 diabetes.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"138 ","pages":"Pages 33-44"},"PeriodicalIF":3.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143877530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}