Nutrition Research最新文献

{"title":"A reflection-spectroscopy measured skin carotenoid score strongly correlates with plasma concentrations of all major dietary carotenoid species except for lycopene","authors":"Qiang Wu ,&nbsp;Cheryl Webb Cherry ,&nbsp;Stephanie Jilcott Pitts ,&nbsp;Melissa N. Laska ,&nbsp;Neal Craft ,&nbsp;Nancy E. Moran","doi":"10.1016/j.nutres.2024.11.010","DOIUrl":"10.1016/j.nutres.2024.11.010","url":null,"abstract":"<div><div>Skin carotenoids can be measured non-invasively using spectroscopy methods to provide a biomarker of total dietary carotenoid and carotenoid-rich fruit and vegetable intake. However, the degree to which skin carotenoid biomarkers reflect intakes of specific carotenoids must be determined for specific devices. Previously, findings were mixed regarding the correlation between reflection spectroscopy (RS)-assessed skin carotenoids and individual plasma carotenoid concentrations. The current study expands on prior analyses to examine the cross-sectional associations between adult RS-assessed skin carotenoids and individual carotenoid species intakes and plasma concentrations, controlling for potential covariates. We hypothesized that RS-assessed skin carotenoid scores would strongly correlate with all major plasma carotenoid species other than lycopene. Cross-sectional data from 2 prior studies (n = 213 and n = 162) examining the validity and sensitivity of RS-assessed skin carotenoids as a biomarker of fruit and vegetable intake were used. Skin carotenoids were assessed using the Veggie Meter, which quantifies combined skin carotenoid concentrations. Plasma concentrations of α-carotene, β-carotene, β-cryptoxanthin, lycopene, and lutein and zeaxanthin were determined using high-performance liquid chromatography. Self-reported carotenoid intake was estimated from validated food frequency questionnaires. Skin carotenoid scores correlated moderately to strongly with individual plasma carotenoid species (Pearson's <em>r</em> = 0.52 to <em>r</em> = 0.78) except for lycopene (<em>r</em> = 0.04 to <em>r</em> = 0.07). Low correlations between skin carotenoid score and lycopene plasma concentrations and intake could be due to differential deposition, preferential oxidation/degradation, and/or device measurement bias. Validating skin carotenoid measurement techniques relative to other concentration biomarkers informs the interpretation of skin carotenoid biomarkers.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"133 ","pages":"Pages 127-137"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and facilitators to healthy eating among college students","authors":"Nicholas Drzal ,&nbsp;Jean M. Kerver ,&nbsp;Rita S. Strakovsky ,&nbsp;Lorraine Weatherspoon ,&nbsp;Katherine Alaimo","doi":"10.1016/j.nutres.2024.06.001","DOIUrl":"10.1016/j.nutres.2024.06.001","url":null,"abstract":"<div><div>Young adulthood is an influential life stage for developing lifelong eating patterns, yet limited research characterizes dietary intake among young adults. This cross-sectional study assessed dietary intake and characteristics associated with nutrition knowledge and healthy food consumption among college students. We hypothesized that healthy food intake would be lower than United States (U.S.) dietary guidelines and that perceived healthy eating barriers would be negatively associated with diet quality. Participants were undergraduate college students enrolled in an introductory human nutrition course (N = 762), with surveys administered during the first week of class. Survey instruments included the Dietary Screener Questionnaire developed by the National Cancer Institute and the Jones Nutrition Knowledge questionnaire. Perceived encouragement, cost, taste, and ease of eating healthier foods were assessed with questions from the National Health Interview Survey. College student daily mean intakes of fiber (15.46 ± 3.06 grams), whole grains (0.63 ± 0.29 ounce equivalents), combined fruits and vegetables (2.38 ± 0.73 cup equivalents), and dairy (1.49 ± 0.53 cup equivalents) were lower than U.S. recommended dietary guidelines, while mean intakes of added sugars (14.65 ± 4.01 teaspoon equivalents) were greater than recommendations. As hypothesized, dietary intakes of young adult college students were sub-optimal, not meeting the U.S. dietary guidelines for fiber, whole grains, fruits, vegetables, dairy, and added sugars. Additionally, perceived ease of eating healthier foods, cost, and nutrition knowledge were significantly associated with increased consumption of healthier foods. Results highlight the need to reduce barriers to improve healthy eating among young adults.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"133 ","pages":"Pages 161-171"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141394899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial office and Board Members","authors":"","doi":"10.1016/S0271-5317(25)00010-7","DOIUrl":"10.1016/S0271-5317(25)00010-7","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"133 ","pages":"Pages i-ii"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial office and Board Members","authors":"","doi":"10.1016/S0271-5317(24)00159-3","DOIUrl":"10.1016/S0271-5317(24)00159-3","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"132 ","pages":"Pages i-ii"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"David Kritchevsky Graduate Student Award for Nutrition Research","authors":"","doi":"10.1016/S0271-5317(24)00160-X","DOIUrl":"10.1016/S0271-5317(24)00160-X","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"132 ","pages":"Page iii"},"PeriodicalIF":3.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143154292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polyphenols from Prunus salicina L. alleviate weight gain, obesity-related hyperlipidemia, hepatic steatosis, hyperglycemia, and modulate gut microbiota in mice fed a high-fat diet","authors":"Haizhao Song ,&nbsp;Jing Lu ,&nbsp;Qiang Chu","doi":"10.1016/j.nutres.2024.11.001","DOIUrl":"10.1016/j.nutres.2024.11.001","url":null,"abstract":"<div><div>Hyperlipidemia, hepatic steatosis, and hyperglycemia are prevalent metabolic disorders closely linked to obesity. The objective of this research was to examine the potential advantageous impacts of polyphenols extracted from <em>Prunus salicina</em> L. fruit (PSFP) on hyperlipidemia, hepatic steatosis, and hyperglycemia induced by a high-fat diet (HFD), as well as to elucidate the underlying mechanisms involved. Male C57BL/6J mice, free from specific pathogens, were assigned randomly into three groups. These groups were then subjected to a 14-week dietary intervention, including a low-fat diet, an HFD, or an HFD plus with PSFP via intragastric administration. The obesity-related biochemical indexes were evaluated. To assess alterations in gut microbiota resulting from PSFP treatment, 16S rRNA sequencing was performed. UPLC-ESI-MS/MS assay identified 162 distinct polyphenolic compounds in PSFP. The administration of PSFP significantly reduced both body weight gain and hyperlipidemia induced by HFD. In addition, PSFP ameliorated hepatic steatosis induced by HFD and enhanced liver function in mice. PSFP treatment also ameliorated HFD-induced insulin resistance and hyperglycemia, evidenced by the observed decrease in fasting serum concentrations of glucose and insulin, improved insulin sensitivity, and restored glucose tolerance. Moreover, PSFP modulated the composition and abundance of specific microbial genus, including <em>Lachnospiraceae NK4A136 group, Akkermansia, Parabacteroides, Enterococcus, Adlercreutzia</em>, and <em>Roseburia</em>. Correlation analysis indicated significant associations between gut microbiota and physiological indices associated with obesity. These findings suggested that PSFP supplementation ameliorated HFD-induced hyperlipidemia, hepatic steatosis, and hyperglycemia, potentially through modulating the gut microbiota composition and abundance of specific taxa.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"132 ","pages":"Pages 152-163"},"PeriodicalIF":3.4,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142704376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Whole milk intake is associated with lower body weight and body mass index in American adults","authors":"Moises Torres-Gonzalez ,&nbsp;Matthew A. Pikosky ,&nbsp;Kristin Ricklefs-Johnson ,&nbsp;Kristin Fulgoni ,&nbsp;Victor L. Fulgoni III ,&nbsp;Sanjiv Agarwal ,&nbsp;Christopher J. Cifelli","doi":"10.1016/j.nutres.2024.11.002","DOIUrl":"10.1016/j.nutres.2024.11.002","url":null,"abstract":"<div><div>The objective was to determine if whole milk intake or total milk intake behaviors are associated with body weight (weight) and related parameters in adults. We hypothesize that whole milk intake would be inversely associated with body weight measures. Whole milk (including flavored whole milk) intake was assessed using 24-hour dietary recall data of the National Health and Nutrition Examination Survey 2001-2018 for adults age 20+ years (<em>N</em> = 43,038). Weight and related parameters were measured, and history of self-reported weights and total milk intake were obtained from questionnaire data. The association of whole milk intake with weight was assessed via regression after adjusting for demographic and lifestyle-related covariates. The average body mass index (BMI) was about 29 kg/m² and weight was 76 to 89 kg. About 66% of the population were overweight or obese. Average whole milk intake among consumers was 1.0 to 1.4 cups eq/d. Whole milk intake was inversely associated (<em>P</em> &lt; .05) with weight, BMI, waist circumference, and the prevalence of obesity. Whole milk intake was also inversely associated (<em>P</em> &lt; .01) with trying to lose weight in the past year. In most cases, milk intake behavior at ages 5 to 12, 13 to 17, or 18 to 35 years was not associated with BMI. The results indicate that whole milk intake was inversely associated with weight, BMI, and prevalence of obesity, and these findings may provide additional evidence to support dietary recommendations for whole milk.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"132 ","pages":"Pages 180-189"},"PeriodicalIF":3.4,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"David Kritchevsky Graduate Student Award for Nutrition Research","authors":"","doi":"10.1016/S0271-5317(24)00147-7","DOIUrl":"10.1016/S0271-5317(24)00147-7","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"131 ","pages":"Page iii"},"PeriodicalIF":3.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial office and Board Members","authors":"","doi":"10.1016/S0271-5317(24)00146-5","DOIUrl":"10.1016/S0271-5317(24)00146-5","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"131 ","pages":"Pages i-ii"},"PeriodicalIF":3.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polyphenols have unique cellular effects that are distinct from antioxidant function in Toll-like receptor 4–mediated inflammation in RAW264.7 macrophage-like cells","authors":"Rami S. Najjar ,&nbsp;Wesley W. Grace ,&nbsp;Ana P.S. Siqueira ,&nbsp;Alivia M. Setka ,&nbsp;Wen Lu ,&nbsp;Siming Wang ,&nbsp;Rafaela G. Feresin","doi":"10.1016/j.nutres.2024.10.007","DOIUrl":"10.1016/j.nutres.2024.10.007","url":null,"abstract":"<div><div>Plant polyphenols are bioactive compounds touted for their antioxidant effects, and this is often the primary attribute used to explain their health benefits. However, we hypothesize that polyphenols have molecular properties independent of antioxidant function. The objective of this study was to investigate whether polyphenols had distinct molecular effects compared to pure antioxidants. RAW 264.7 macrophages were pretreated with either TEMPOL, a superoxide scavenger, N-acetyl cysteine, a hydroxyl radical and hydrogen peroxide scavenger, or polyphenol extracts from blackberry, blueberry, raspberry, strawberry, kale, and baru nut. After 1 hour of pretreatment, cells were treated with lipopolysaccharides (100 ng/mL) for an additional 6 hour. Antioxidants and polyphenol extracts elicited antioxidant effects in vitro; however, polyphenols regulated redox proteins in a distinct, protective manner, whereas antioxidants, TEMPOL, and N-acetyl cysteine, did not. Additionally, distinct effects were observed in downstream Toll-like receptor 4 signaling and transcriptional activity of inflammatory proteins. We conclude that polyphenols have unique molecular effects that are independent of just their free radical scavenging capacity. This work advances our molecular understanding of how polyphenols act to target inflammation.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"132 ","pages":"Pages 136-151"},"PeriodicalIF":3.4,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142704377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}