Nutrition ResearchPub Date : 2025-10-01Epub Date: 2025-07-10DOI: 10.1016/j.nutres.2025.07.002
Jaz Lyons-Reid , Leigh C. Ward , Jo Secher , Mohammad Shahbaz , Benjamin B. Albert , Wayne S. Cutfield , José G.B. Derraik
{"title":"Claims of group-level accuracy for bioelectrical impedance analysis in paediatric obesity: a cautionary note","authors":"Jaz Lyons-Reid , Leigh C. Ward , Jo Secher , Mohammad Shahbaz , Benjamin B. Albert , Wayne S. Cutfield , José G.B. Derraik","doi":"10.1016/j.nutres.2025.07.002","DOIUrl":"10.1016/j.nutres.2025.07.002","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"142 ","pages":"Pages 94-96"},"PeriodicalIF":3.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition ResearchPub Date : 2025-10-01Epub Date: 2025-07-17DOI: 10.1016/j.nutres.2025.07.005
Richard S Bruno
{"title":"Bridging nutritional mechanisms and global challenges: The 2024 David Kritchevsky award winners","authors":"Richard S Bruno","doi":"10.1016/j.nutres.2025.07.005","DOIUrl":"10.1016/j.nutres.2025.07.005","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"142 ","pages":"Pages A1-A5"},"PeriodicalIF":3.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition ResearchPub Date : 2025-10-01Epub Date: 2025-09-04DOI: 10.1016/j.nutres.2025.08.009
Vasiliki Bountziouka , Christopher P. Nelson , Veryan Codd , Nilesh J. Samani
{"title":"Higher dietary n - 3 PUFA and fiber intake are associated with longer leukocyte telomere length: Evidence from a substitution model analysis in the UK Biobank","authors":"Vasiliki Bountziouka , Christopher P. Nelson , Veryan Codd , Nilesh J. Samani","doi":"10.1016/j.nutres.2025.08.009","DOIUrl":"10.1016/j.nutres.2025.08.009","url":null,"abstract":"<div><div>Telomere attrition is a biomarker of cellular aging, influenced by lifestyle and dietary exposures. The specific role of macronutrient composition, particularly polyunsaturated fatty acids (PUFAs), in telomere dynamics remains insufficiently explored. We hypothesized that higher intake of specific macronutrients, particularly PUFAs, would be positively associated with leukocyte telomere length (LTL). In this cross-sectional study of 143,553 UK Biobank participants aged 40-69 years, we examined associations between macronutrient intake and standardized LTL (z-LTL), measured as the log-transformed telomere repeat to single-copy gene ratio. Dietary intake was assessed using repeated 24-hour web-based dietary recalls. Multivariable linear regression models were used to estimate associations between macronutrients (% of total energy intake) and z-LTL, adjusting for demographic, lifestyle, and clinical covariates. Effect estimates were translated into age-equivalent changes in LTL. Carbohydrate and total fat intake were positively associated with z-LTL, corresponding to age-related LTL differences of approximately 30-40 days. In energy substitution models, <em>n</em> - 3 PUFA intake showed a stronger positive association with z-LTL than other fats, with adherence to recommended intake associated with differences equivalent to over 2 years (<em>P < .</em>0001) of age-related telomere shortening, whereas no evidence of an association for MUFA was observed. Energy-adjusted fibre intake was associated with an age-related change of LTL equivalent to 1 year (<em>P < .</em>0001). These findings suggest that dietary composition, particularly <em>n</em> - 3 PUFA intake, may be linked with LTL in a manner consistent with healthier cellular aging. Further longitudinal and experimental studies are needed to confirm these associations and explore their implications for dietary guidance.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"142 ","pages":"Pages 63-75"},"PeriodicalIF":3.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition ResearchPub Date : 2025-10-01Epub Date: 2025-08-27DOI: 10.1016/j.nutres.2025.08.008
Jonas Benjamim
{"title":"The devil is in the details: Reassessing an isolation attempt reveals methodological breaches in dietary inorganic nitrate research","authors":"Jonas Benjamim","doi":"10.1016/j.nutres.2025.08.008","DOIUrl":"10.1016/j.nutres.2025.08.008","url":null,"abstract":"","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"142 ","pages":"Pages 104-107"},"PeriodicalIF":3.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition ResearchPub Date : 2025-10-01Epub Date: 2025-08-15DOI: 10.1016/j.nutres.2025.08.005
Yujin Cho , Jeonghee Lee , Madhawa Gunathilake , Youngyo Kim , Shinyoung Jun , Jeongseon Kim
{"title":"A higher intake of white-edible-colored fruits and vegetables is associated with lower gastrointestinal cancer risk among Korean adults in a prospective cohort study","authors":"Yujin Cho , Jeonghee Lee , Madhawa Gunathilake , Youngyo Kim , Shinyoung Jun , Jeongseon Kim","doi":"10.1016/j.nutres.2025.08.005","DOIUrl":"10.1016/j.nutres.2025.08.005","url":null,"abstract":"<div><div>Although fruits and vegetables were studied botanically in previous studies, few have examined their associations with gastrointestinal (GI) cancer risk based on color classification. Color is familiar to the public and translates phytochemical science into dietary guidance. We hypothesized that the intake of fruits and vegetables would be differently associated with GI cancer risk by color. This cohort study investigated the association between fruit and vegetable colors and GI cancer risk in 11,286 participants from the Cancer Screenee Cohort, who underwent health check-ups at the National Cancer Center between 2007 and 2021. Dietary data were collected through food frequency questionnaires. A Cox proportional hazards regression model evaluated the association between fruit and vegetable color groups (green, orange/yellow, red/purple, and white) and GI cancer risk. Over a mean follow-up of 8 years, 214 GI cancers (esophageal, gastric, small intestine, liver, pancreatic, and colorectal) were identified. Higher total fruit and vegetable intake was associated with reduced GI cancer risk (hazard ratio [HR] = 0.57, 95% confidence interval [CI]: 0.38-0.88, <em>P</em> for trend = .013). Among color groups, white-colored fruits and vegetables (HR = 0.64, 95% CI: 0.41-0.99, <em>P</em> for trend = .021), and white-colored fruits (HR = 0.59, 95% CI: 0.38-0.92, <em>P</em> for trend = .021) were associated with a lower risk of GI cancer after fully adjusting for demographic variables, dietary factors, and comorbidities. Findings were consistent across subgroup analyses. No significant associations were found for green, orange/yellow, or red/purple groups. These results suggest that white-colored fruits and vegetables may contribute to GI cancer prevention.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"142 ","pages":"Pages 1-15"},"PeriodicalIF":3.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition ResearchPub Date : 2025-10-01Epub Date: 2025-09-04DOI: 10.1016/j.nutres.2025.09.002
Hang Zhang , Li Li , Yuwei Wang , Yuhan Xie , Bing Chen
{"title":"Moderate carotenoid intakes protect against sarcopenic obesity among U.S. adults: A cross-sectional study","authors":"Hang Zhang , Li Li , Yuwei Wang , Yuhan Xie , Bing Chen","doi":"10.1016/j.nutres.2025.09.002","DOIUrl":"10.1016/j.nutres.2025.09.002","url":null,"abstract":"<div><div>Carotenoids have been recognized for their potential health benefits due to their potent anti-inflammatory and antioxidant properties. However, evidence regarding the specific relationship between carotenoid intake and sarcopenic obesity (SO) remains limited. We hypothesized that moderate carotenoid intake was associated with a lower SO risk. A cross-sectional study was conducted involving 10,060 adults aged 18 to 59 from the National Health and Nutrition Examination Survey 2011-2018. Whole-body composition was assessed by dual-energy X-ray absorptiometry, while carotenoid intake was obtained through two 24-hour dietary recall interviews. Weighted logistic regression models, stratified analyses, restricted cubic spline analyses, and sensitivity analyses were utilized for this study. The weighted prevalence of SO was 7.51%. Weighted logistic regression revealed that dietary α-carotene, β-carotene, and β-cryptoxanthin intake was inversely associated with SO risk after accounting for various variables. Age-stratified analyses revealed a significant inverse association between α-carotene intake and SO risk among adults aged 40 to 59, whereas β-carotene and β-cryptoxanthin exhibited similar inverse relationships in the 18 to 39 age group. The sex-stratified analysis demonstrated that the highest tertile of α-carotene, β-carotene, and β-cryptoxanthin intake was inversely correlated with the risk of SO among females. Restricted cubic spline regression analysis revealed a U-shaped association between dietary intake of α-carotene, β-carotene, and β-cryptoxanthin with SO risk, particularly in 40-59-year-olds and females. In conclusion, moderate dietary α-carotene (0.77 mg/day), β-carotene (3.93 mg/day), and β-cryptoxanthin (0.19 mg/day) consumption was associated with a lower SO risk. The relationship between these carotenoids and SO was nonlinear, particularly among individuals aged 40 to 59 years and in females.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"142 ","pages":"Pages 46-62"},"PeriodicalIF":3.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145156508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition ResearchPub Date : 2025-10-01Epub Date: 2025-05-23DOI: 10.1016/j.nutres.2025.05.003
Badreya Al-Lahou , Lynne M. Ausman , José L. Peñalvo , Gordon S. Huggins , Fang Fang Zhang
{"title":"Diet quality of a population from a high-income gulf country in the era of transition: Kuwait as a model example","authors":"Badreya Al-Lahou , Lynne M. Ausman , José L. Peñalvo , Gordon S. Huggins , Fang Fang Zhang","doi":"10.1016/j.nutres.2025.05.003","DOIUrl":"10.1016/j.nutres.2025.05.003","url":null,"abstract":"<div><div>Diet is a modifiable risk factor for cardiovascular diseases (CVD). While the rate of CVD is escalating in Kuwait, studies examining dietary intake in the Kuwaiti population are scarce. This study aimed to evaluate the diet quality of a nationally representative sample of Kuwaiti adults using the first and only National Nutrition Survey. Dietary intake was assessed using a 24-hour dietary recall among 980 adults aged 20 years or older. Diet quality was evaluated using the American Heart Association (AHA) diet score. Intake and scores of the AHA components were analyzed for the total sample and stratified by age and sex using complex survey regression models adjusted for sampling weights. The mean AHA diet score (maximum 80) was 42.5 ± 0.46. Over 70% of adults consumed insufficient amounts of fruits/vegetables, whole grains, fish/shellfish, and nuts/seeds/legumes, while nearly 80% exceeded saturated fat limits and over 95% exceeded sodium recommendations. Diet quality scores increased significantly with age (<em>P</em> < .0001), with older adults (≥60 years, score = 49.4) scoring notably higher than younger adults (<30 years, score = 37.4). Younger adults had particularly low intake of fruits, vegetables, whole grains, and fish, while no differences were observed for sodium or nuts/seeds/legumes. Overall diet quality did not differ significantly by sex. Suboptimal diet quality was prevalent, particularly among younger adults in Kuwait. This study underscores the urgent need for targeted dietary improvements and establishes a crucial reference point for future public health initiatives.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"142 ","pages":"Pages 23-32"},"PeriodicalIF":3.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nutrition ResearchPub Date : 2025-10-01Epub Date: 2025-09-08DOI: 10.1016/j.nutres.2025.09.003
Eva Keohane , Jessica Prenni , Sarah A. Johnson , Charlene Van Buiten
{"title":"Comparing apples to apples: Evaluating foodomics in precision nutrition research featuring the influence of polyphenols on the gut microbiome","authors":"Eva Keohane , Jessica Prenni , Sarah A. Johnson , Charlene Van Buiten","doi":"10.1016/j.nutres.2025.09.003","DOIUrl":"10.1016/j.nutres.2025.09.003","url":null,"abstract":"<div><div>This review aimed to evaluate the use of advanced omics methodologies in dietary intervention clinical trials investigating the influence of polyphenols on the gut microbiome. All published clinical studies in the Cochrane Library database from 2014 to 2024 containing the keywords “polyphenols” and “gut microbiome” were compiled and categorized based on experimental design, analytical methodologies, and findings. We found that despite known variability in food composition across agricultural and processing parameters, omics analysis of the food used in clinical nutrition interventions has not been widely embraced. None of the studies evaluated employed untargeted omics approaches for food composition analysis, while 5 of the 38 studies used untargeted omics for clinical samples analysis. Targeted analytical methods focused on known compounds or proxies were more commonly used for food composition analysis (18 of 38 studies) and clinical samples (24 of 38 studies), though analysis of clinical samples focused on a greater number of target compounds. Data from these studies support relationships between the gut microbiome, clinical outcomes, and specific metabolites. However, several studies highlight inconsistencies between their findings and previous literature, which may be attributed to unrealized differences in polyphenol composition. We propose that inclusion of comprehensive omics-based food composition analyses in dietary intervention clinical trials may increase study value by accounting for variability in food composition and enabling novel discovery. Such data would support the emerging fields of personalized and precision nutrition, aimed at understanding the influence of individual human characteristics on physiological responses to foods, nutrients, phytochemicals, and dietary patterns.</div></div>","PeriodicalId":19245,"journal":{"name":"Nutrition Research","volume":"142 ","pages":"Pages 76-90"},"PeriodicalIF":3.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145200528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}