Journal of investigative medicine high impact case reports最新文献_第6页

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2025-01-01 DOI: 10.1177/23247096251316453

引用次数: 0

Abdominal Actinomycosis Abscess Mimicking Malignancy: A Case Report and Review of the Literature. 腹部模拟恶性脓肿放线菌病1例报告及文献复习。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2025-01-01 DOI: 10.1177/23247096251316374

Yosra Loukil, Saadia Makni, Youssef Mejdoub, Haitham Rejab, Nozha Toumi, Slim Charfi, Tahya Sallemi Boudawara, Marwa Bouhamed

引用次数: 0

Unveiling Rare Pulmonary Complications in Infective Endocarditis: Pneumatoceles and Pneumothorax in a Case Series With Contextual Literature Review. 揭示感染性心内膜炎的罕见肺部并发症：气肿和气胸的病例系列与相关文献回顾。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2025-01-01 Epub Date: 2025-04-11 DOI: 10.1177/23247096251334228

Nagihan Orhun, Islam Rajab, Utku Ekin, George Horani, Mourad Ismail

引用次数: 0

Unveiling the Link Between Breast Cancer and Liver Abscess: A Case Report and Review of Literature. 揭示乳腺癌与肝脓肿的关系：1例报告及文献复习。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2025-01-01 Epub Date: 2025-04-12 DOI: 10.1177/23247096251334232

Jayalekshmi Jayakumar, Manasa Ginjupalli, Giovannie Isaac Coss, Fiqe Khan, Daniel Stein, Davin Turku, Khalimullah Quadri

{"title":"Unveiling the Link Between Breast Cancer and Liver Abscess: A Case Report and Review of Literature.","authors":"Jayalekshmi Jayakumar, Manasa Ginjupalli, Giovannie Isaac Coss, Fiqe Khan, Daniel Stein, Davin Turku, Khalimullah Quadri","doi":"10.1177/23247096251334232","DOIUrl":"https://doi.org/10.1177/23247096251334232","url":null,"abstract":"The introduction of screening mammograms has revolutionized the early detection of breast cancer. However, it remains the most common cancer in women in the United States, excluding skin cancer. As the incidence rates continue to rise, unusual presentations have become more frequent. Additionally, healthcare barriers can lead to delayed detection of breast cancer, resulting in unexpected complications. The occurrence of pyogenic liver abscess (PLA) in diabetic cancer patients, due to the synergistic effect of insulin-like growth factor-1 in tumorigenesis and abscess formation, is well documented. PLA is also prevalent in hepatocellular, colorectal, and pancreato-biliary tumors. However, the occurrence of PLA as an initial presentation of isolated advanced breast cancer without these comorbidities is understudied. This may be due to direct spread of infection from affected skin or spread via lymphatics or vasculature in the setting of immunosuppression from cancer. We present an exceedingly rare case of PLA, complicated by pulmonary embolism, in an elderly female with newly diagnosed stage IIIB breast carcinoma.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":"13 ","pages":"23247096251334232"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring Extubation Readiness in Guillain-Barré Syndrome: A Case Report and Literature Review. 探讨格林-巴勒综合征的拔管准备情况：1例报告和文献复习。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2025-01-01 Epub Date: 2025-05-08 DOI: 10.1177/23247096251331859

Victoria Watson, Saif Ghishan, Tata Avalishvili, Sinen Zeleke, Saron Tigabe, Anderson White, Fuad Zeid, Zakaria Alagha

{"title":"Exploring Extubation Readiness in Guillain-Barré Syndrome: A Case Report and Literature Review.","authors":"Victoria Watson, Saif Ghishan, Tata Avalishvili, Sinen Zeleke, Saron Tigabe, Anderson White, Fuad Zeid, Zakaria Alagha","doi":"10.1177/23247096251331859","DOIUrl":"https://doi.org/10.1177/23247096251331859","url":null,"abstract":"Guillain-Barré Syndrome (GBS) is an acute immune-mediated polyneuropathy causing rapidly progressive muscle weakness and often respiratory failure, requiring mechanical ventilation in 30% of cases. Successful weaning and extubation are crucial, focusing on readiness for spontaneous breathing trials, optimal timing, and minimizing complications such as ventilator-associated pneumonia and extubation failure. This case report describes an 83-year-old male with multiple comorbidities who was intubated after his negative inspiratory force dropped below -30 cm H₂O and treated with plasmapheresis, leading to partial improvement. Despite not meeting standard extubation criteria, he was successfully extubated, maintained stable respiratory function, and was safely discharged. This case highlights the challenges of extubation in GBS patients, where advanced age, decreased physiological reserve, and comorbidities increase the risks of prolonged intubation and complications. This case also highlights the need for individualized extubation strategies in GBS, particularly in elderly patients who may not meet standard criteria. Tailored approaches can still lead to successful outcomes. Based on our institutional experience, we propose factors that predict the success or failure of extubation in these patients. Further research is needed to refine predictive markers and improve extubation success in this population, ultimately enhancing outcomes and reducing ICU and hospital stays.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":"13 ","pages":"23247096251331859"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12062643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peripartum Cardiomyopathy as the Initial Manifestation of Undiagnosed Sickle Cell Disease: A Case Report. 围产期心肌病作为未确诊镰状细胞病的初始表现：1例报告。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2025-01-01 Epub Date: 2025-05-31 DOI: 10.1177/23247096251346829

Pedro Pallangyo, Zabella Mkojera, Loveness Mfanga, Makrina Komba, Peter R Kisenge

{"title":"Peripartum Cardiomyopathy as the Initial Manifestation of Undiagnosed Sickle Cell Disease: A Case Report.","authors":"Pedro Pallangyo, Zabella Mkojera, Loveness Mfanga, Makrina Komba, Peter R Kisenge","doi":"10.1177/23247096251346829","DOIUrl":"10.1177/23247096251346829","url":null,"abstract":"Peripartum cardiomyopathy (PPCM) occurring in the context of sickle cell disease (SCD) is exceedingly rare, particularly as the initial presentation of undiagnosed SCD. We report the case of a 39-year-old African primigravida at 36 weeks of gestation who presented with a 1-week history of heart failure symptoms. Her antenatal course was largely uneventful apart from severe anemia, for which she was transfused 2 units of whole blood followed by prescription of hematinics. Laboratory investigations revealed hemolytic anemia, a positive sickling test, and confirmatory hemoglobin electrophoresis demonstrating 93% sickle hemoglobin and 4.1% hemoglobin fetal, establishing a new diagnosis of homozygous SCD. Transthoracic echocardiography revealed a severely reduced left ventricular ejection fraction (LVEF 26%) and dilated left heart chambers, consistent with a diagnosis of PPCM. She was admitted to the maternity intensive care unit and managed by a multidisciplinary team, with stabilization on supportive therapy. At 38 weeks, she underwent a successful elective cesarean section, followed by an uneventful postpartum recovery. She was discharged 9 days postpartum in a stable condition (New York Heart Association Class II) on guideline-directed medical therapy and enrolled in outpatient follow-up. At 6 months, follow-up echocardiography showed partial recovery of cardiac function with an LVEF of 38%. She continues to be monitored by cardiology and hematology teams. This case highlights the critical importance of considering underlying hemoglobinopathies in pregnant patients presenting with unexplained heart failure, especially in regions where SCD is endemic.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":"13 ","pages":"23247096251346829"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transient Supine-Induced Advanced Heart Block in an Octogenarian. 一名八旬老人短暂仰卧诱发的晚期心脏传导阻滞。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2025-01-01 Epub Date: 2025-05-31 DOI: 10.1177/23247096251345375

Lakshmipathi Peram, Priya Ramcharan, Matthew Maharaj, Arun Katwaroo, Stephanie Battersby, Valmiki Seecheran, Rajeev Seecheran, Naveen Seecheran

引用次数: 0

Radiographic Convergence: A Case of Pneumomediastinum, Pneumothorax, Pneumopericardium, and Subcutaneous Emphysema. 纵隔气肿、气胸、心包气肿及皮下肺气肿1例。

IF 0.8

Journal of investigative medicine high impact case reports Pub Date : 2025-01-01 Epub Date: 2025-08-27 DOI: 10.1177/23247096251367550

Nizar Alyassin, Islam Rajab, Sabrina Higgins, Michael Pelidis, Ruth Lamm

引用次数: 0

A Fatal Case of Acute Necrotizing Pancreatitis Following a COVID-19 Vaccine. 接种COVID-19疫苗后急性坏死性胰腺炎的致命病例

IF 0.8

Journal of investigative medicine high impact case reports Pub Date : 2025-01-01 Epub Date: 2025-08-30 DOI: 10.1177/23247096251367809

D'Argent Louise, Lormans Piet, Dumoulein Alexander, Schockaert Bernard

{"title":"A Fatal Case of Acute Necrotizing Pancreatitis Following a COVID-19 Vaccine.","authors":"D'Argent Louise, Lormans Piet, Dumoulein Alexander, Schockaert Bernard","doi":"10.1177/23247096251367809","DOIUrl":"https://doi.org/10.1177/23247096251367809","url":null,"abstract":"Several adverse effects have been reported following the use of the Pfizer-BioNTech mRNA vaccine against COVID-19 infection with acute pancreatitis being one of those. However, a direct relationship between the vaccine and the occurrence of acute pancreatitis has not been confirmed. Hereby, a case of an acute necrotizing pancreatitis resulting in fatal outcome following the administration of the COVID-19 BioNTech Pfizer vaccine is presented. A 70-year-old male presented with abdominal pain 4 days after receiving his fifth dose of the COVID-19 BioNTech Pfizer vaccine. Laboratory examination showed lipase levels of 2000 U/L. A CT scan was performed and showed necrotizing pancreatitis. After detailed evaluation, no etiological cause of pancreatitis could be found in this patient. The patient was admitted to the intensive care unit. After a disease course of ~6 weeks, the patient died due to multiorgan failure. This case presentation takes into account previously reported cases of acute pancreatitis following COVID-19 vaccination. To our knowledge, this is the first case of acute pancreatitis with fatal ending following a COVID-19 vaccination. This highlights the importance of thorough evaluation of patients presenting with abdominal pain following the administration of a COVID-19 vaccine.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":"13 ","pages":"23247096251367809"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12399823/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stanford Type B Aortic Dissection in a Patient With Osteogenesis Imperfecta: A Case Report. 成骨不全患者的Stanford B型主动脉夹层一例报告。

IF 0.8

Journal of investigative medicine high impact case reports Pub Date : 2025-01-01 Epub Date: 2025-09-13 DOI: 10.1177/23247096251377178

Harsh Patel

{"title":"Stanford Type B Aortic Dissection in a Patient With Osteogenesis Imperfecta: A Case Report.","authors":"Harsh Patel","doi":"10.1177/23247096251377178","DOIUrl":"10.1177/23247096251377178","url":null,"abstract":"Osteogenesis imperfecta is a group of rare, genetically inherited, autosomal dominant connective tissue disorders affecting the production of type-1 collagen. The most common cardiovascular manifestations of the pathology include aortic regurgitation and aortic root disease. Other manifestations remain particularly rare, with only 2 previously reported cases of type B aortic dissection in patients with osteogenesis imperfecta described in the literature. The management of vascular pathology in connective tissue disease remains a significant clinical challenge due to the intrinsic fragility of connective tissues and tendencies to bleed with open surgical repair. This is a case of a 69-year-old with a genetically confirmed diagnosis of osteogenesis imperfecta presenting with epigastric pain radiating to the back. She had vascular risk factors of hypertension and hypercholesterolaemia. Imaging revealed an acute, uncomplicated Stanford Type B aortic dissection, which was managed with intravenous and then oral beta-blocker therapy. Close imaging surveillance demonstrated stability in the extent of the dissection, and she remains asymptomatic at 6 months of follow-up. Notably, her inpatient stay was complicated by a reactive pleural effusion, which resolved without intervention. Given the rarity of aortic dissection in patients with osteogenesis imperfecta and the lack of clinical evidence to guide decision-making, this case report emphasizes the importance of an individualized approach to management in the acute phase with intensive outpatient surveillance. Awareness of the risks posed by connective tissue fragility in this patient population is essential in guiding both emergency and elective surgical management and long-term care planning.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":"13 ","pages":"23247096251377178"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12433543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145054138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0