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Enteric Duplication Cyst Associated With Meckel's Diverticulum: A Rare Cause of Acute Abdomen. 伴有梅克尔憩室的肠套叠囊肿：急性腹部的罕见病因。
IF 0.9
Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241271986
Kugendran Ponniah, Stephen Kinsey-Trotman, Naveen Agarwal, Dandie Lachlan, Matthew Kozman
{"title":"Enteric Duplication Cyst Associated With Meckel's Diverticulum: A Rare Cause of Acute Abdomen.","authors":"Kugendran Ponniah, Stephen Kinsey-Trotman, Naveen Agarwal, Dandie Lachlan, Matthew Kozman","doi":"10.1177/23247096241271986","DOIUrl":"10.1177/23247096241271986","url":null,"abstract":"<p><p>We report a case of a 26-year-old type 1 diabetic woman presenting with acute lower abdominal pain, bloating, and vomiting. Initial examination revealed right lower quadrant tenderness and a suprapubic mass. Computed tomography (CT) imaging identified a 12-cm cystic structure suggestive of a dilated bowel loop with an adjacent inflamed 7-cm small bowel segment. Surgical exploration uncovered a Merkel's diverticulum-associated duplication cyst originating from the Meckel's diverticulum. Subsequent complications included an anastomotic leak, requiring relook laparotomy and the formation of a double-barrel stoma. The patient recovered and was discharged on day 13. This case highlights the diagnostic challenge of Meckel's diverticulum-associated duplication cysts, emphasizing the need for vigilance in managing complex abdominal presentations.</p>","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Perfect Storm: Abnormal Baseline QT With Chronic Methadone Use and Serious Hypokalemia. 完美风暴长期服用美沙酮导致基线 QT 异常和严重低钾血症。
IF 0.9
Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241286373
Oscar J Lopez, Diana Othon, Yilen K Ng-Wong, Jose Sleiman
{"title":"The Perfect Storm: Abnormal Baseline QT With Chronic Methadone Use and Serious Hypokalemia.","authors":"Oscar J Lopez, Diana Othon, Yilen K Ng-Wong, Jose Sleiman","doi":"10.1177/23247096241286373","DOIUrl":"10.1177/23247096241286373","url":null,"abstract":"<p><p>Methadone, a well-known drug used for pain control and as a treatment for opioid addiction, can cause arrhythmias, including torsades de pointes (TdP), which may progress to ventricular fibrillation and sudden death. We present a case of a middle-aged woman with a long history of methadone use who presented to the emergency department after experiencing cardiac arrest at home. During her hospitalization, she experienced multiple episodes of TdP that improved with isoproterenol and potassium correction. The initial diagnosis was methadone-induced prolonged QT. However, even with discontinuation of methadone, her QTc remained prolonged. Congenital long QT syndrome was suspected, and genetic testing was instructed to test in the outpatient setting. She was discharged on nadolol and a LifeVest.</p>","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11470488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Küttner's Tumor and Autoimmune Pancreatitis as Metachronous Manifestations of IgG4-Related Disease. 库特纳肿瘤和自身免疫性胰腺炎是IgG4相关疾病的同步表现
IF 0.9
Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241286368
Lefika Bathobakae, Rammy Bashir, Heba Farhan, Aneeqa Shahid, Katrina Villegas, Gabriel Melki, Kamal Amer, Yana Cavanagh
{"title":"Küttner's Tumor and Autoimmune Pancreatitis as Metachronous Manifestations of IgG4-Related Disease.","authors":"Lefika Bathobakae, Rammy Bashir, Heba Farhan, Aneeqa Shahid, Katrina Villegas, Gabriel Melki, Kamal Amer, Yana Cavanagh","doi":"10.1177/23247096241286368","DOIUrl":"10.1177/23247096241286368","url":null,"abstract":"<p><p>Immunoglobulin G4-related disease (IgG4-RD) is a multiorgan, fibro-inflammatory condition that presents with painless organ swelling, lymphoplasmacytic infiltration, and obliterative phlebitis, often showing a favorable response to corticosteroid therapy. The most affected organs include the pancreas, kidneys, retroperitoneum, lacrimal glands, and salivary glands. Diagnosis relies on serological, imaging, and histopathological findings, with glucocorticoids as the primary treatment. Despite its reversible nature and good prognosis in many cases, long-term complications such as organ dysfunction or malignancy can still occur. International collaborative efforts have enhanced the understanding, diagnosis, and management of IgG4-RD, emphasizing the importance of comprehensive diagnostic criteria and appropriate therapeutic strategies. Herein, we present an interesting case of a geriatric male who was referred to our clinic because of concern for pancreatic cancer. We diagnosed the patient with autoimmune pancreatitis, a manifestation of IgG4-RD. The patient experienced a dramatic response to steroid therapy and is currently on maintenance therapy.</p>","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11457198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142377961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autoimmune Hemolytic Anemia Associated With Myelodysplastic Syndrome: A Case Report. 骨髓增生异常综合征伴发自身免疫性溶血性贫血：病例报告
IF 0.9
Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241273215
Leonardo Ribeiro, Kemnasom Nwanwene, Khurram Anwar, Mahmoud Abdallah, Mina Shenouda
{"title":"Autoimmune Hemolytic Anemia Associated With Myelodysplastic Syndrome: A Case Report.","authors":"Leonardo Ribeiro, Kemnasom Nwanwene, Khurram Anwar, Mahmoud Abdallah, Mina Shenouda","doi":"10.1177/23247096241273215","DOIUrl":"10.1177/23247096241273215","url":null,"abstract":"<p><p>Myelodysplastic syndrome (MDS) represents a spectrum of myeloid disorders occasionally linked to autoimmune diseases. Here, we present a case of a 60-year-old man demonstrating an unusual coexistence of MDS with warm-autoantibody autoimmune hemolytic anemia (wAIHA). Diagnostic evaluation, including positive direct antiglobulin testing, confirmed the autoimmune etiology of his anemia despite his low-risk MDS classification. Prompt initiation of prednisone therapy resulted in significant hematological and clinical improvement, allowing for a conservative management approach without transfusion requirements. This case underscores the importance of identifying the relationship between wAIHA and MDS, particularly in low-risk scenarios. Moreover, these findings suggest the efficacy of corticosteroids in managing autoimmune anemia in the context of concomitant wAIHA and MDS.</p>","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11342316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ectopic Pancreas at the Ampulla Diagnosed With Endoscopic Snare Papillectomy: A Case Report. 内镜下蜗牛乳头切除术诊断胰腺瓣膜异位：病例报告。
IF 0.9
Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241274299
Lefika Bathobakae, Derya Mücahit, Rammy Bashir, Joseph Russo, Angela Vidreiro, Nader Mekheal, Ruhin Yuridullah, Yana Cavanagh
{"title":"Ectopic Pancreas at the Ampulla Diagnosed With Endoscopic Snare Papillectomy: A Case Report.","authors":"Lefika Bathobakae, Derya Mücahit, Rammy Bashir, Joseph Russo, Angela Vidreiro, Nader Mekheal, Ruhin Yuridullah, Yana Cavanagh","doi":"10.1177/23247096241274299","DOIUrl":"10.1177/23247096241274299","url":null,"abstract":"<p><p>Ectopic pancreas, also known as heterotopic pancreas, is a rare condition in which the pancreatic tissue is found outside its usual location in the gastrointestinal (GI) tract. It is commonly asymptomatic and benign, and is often discovered incidentally during routine imaging, endoscopy, surgery, or autopsy. However, complications can arise, such as inflammation, bleeding, obstruction, or even malignant transformation, necessitating surgical intervention in some cases. Ectopic pancreas at the ampulla of Vater (EPAV) is an extremely rare condition and a diagnostic and therapeutic nightmare. Most cases have been diagnosed through invasive surgery due to concerns for malignancy, which carries significant morbidity and mortality. In our case, endoscopic snare papillectomy (ESP) was employed to establish a diagnosis. Thus far, only one other case has been reported in which ESP was used to diagnose and resect a pancreatic heterotopia at the ampulla.</p>","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11342306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anomalous Right Coronary Artery From Pulmonary Artery Presenting as Inferior Wall Ischemia: A Case Report. 肺动脉异常右冠状动脉表现为下壁缺血：病例报告。
IF 0.9
Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241269935
Bharat Rawlley, Pratyaksh P Vaishnav, Subaina Naeem Khalid, Shweta Paulraj, Ziad A El-Khally, Jamal Ahmed
{"title":"Anomalous Right Coronary Artery From Pulmonary Artery Presenting as Inferior Wall Ischemia: A Case Report.","authors":"Bharat Rawlley, Pratyaksh P Vaishnav, Subaina Naeem Khalid, Shweta Paulraj, Ziad A El-Khally, Jamal Ahmed","doi":"10.1177/23247096241269935","DOIUrl":"10.1177/23247096241269935","url":null,"abstract":"<p><p>We illustrate the case of a 62-year-old man with a symptomatic anomalous right coronary artery from pulmonary artery (ARCAPA). Our patient had presented with dyspnea on exertion with electrocardiogram showing pronounced inferior Q waves and marked inferolateral ST-T wave changes. The patient had a nuclear stress test which showed inferior wall ischemia. Subsequently, the patient underwent coronary angiography which showed an ARCAPA. The patient underwent surgical repair with reimplantation of the right coronary artery to the ascending aorta which was tolerated well. Our case illustrates ARCAPA presenting late in adulthood with ischemic symptoms that was treated with corrective surgery.</p>","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11320399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unusual Case of Delayed-Onset Rituximab-Induced Ventricular Tachycardia: A Case Report. 迟发性利妥昔单抗诱发室性心动过速的罕见病例：病例报告。
IF 0.9
Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241255813
Gevorg Arabyan, Raphi Hambartzhumian, Anthony Martin Lim, Marrey Quizon, Julia Oberndorf, Jonathan Abaya Ghazaleh, Dinesh Sharma
{"title":"An Unusual Case of Delayed-Onset Rituximab-Induced Ventricular Tachycardia: A Case Report.","authors":"Gevorg Arabyan, Raphi Hambartzhumian, Anthony Martin Lim, Marrey Quizon, Julia Oberndorf, Jonathan Abaya Ghazaleh, Dinesh Sharma","doi":"10.1177/23247096241255813","DOIUrl":"10.1177/23247096241255813","url":null,"abstract":"<p><p>Cardiac disease associated with cancer treatment is a common adverse effect that is well-treated with appropriate monitoring. However, some cardiac adverse effects with cancer treatment are not well-understood, in particular rituximab-associated ventricular tachycardia. We present the fourth case of rituximab-associated ventricular tachycardia in a patient who is rituximab-naive and who does not have known cardiac disease history. This patient developed non-sustained polymorphic ventricular tachycardia 14 hours after rituximab was started and 6 hours after it was stopped, and after extensive monitoring including a 30-day event monitor, did not develop further significant runs of ventricular tachycardia.</p>","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11107307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141065599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aortic Aneurysm Mimicking Inferior ST-Elevation Myocardial Infarction: A Case Report. 主动脉瘤诱发下腔 ST 段抬高型心肌梗死：病例报告。
IF 0.9
Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241264634
Ahmed Qasim Mohammed Alhatemi, Ezzat Mohammed Hussain Aziz, Amjed Hussein Alwan Al-Yaseen, Hashim Talib Hashim, Zaid Haitham Abduljabbar, Salwan Qahtan Sultan, Tiba Khalid Abdulhussain, Rand Abdulhussain
{"title":"Aortic Aneurysm Mimicking Inferior ST-Elevation Myocardial Infarction: A Case Report.","authors":"Ahmed Qasim Mohammed Alhatemi, Ezzat Mohammed Hussain Aziz, Amjed Hussein Alwan Al-Yaseen, Hashim Talib Hashim, Zaid Haitham Abduljabbar, Salwan Qahtan Sultan, Tiba Khalid Abdulhussain, Rand Abdulhussain","doi":"10.1177/23247096241264634","DOIUrl":"10.1177/23247096241264634","url":null,"abstract":"<p><p>Here, we report a rare case of a 22-year-old female presenting with recurrent chest pain mimicking inferior ST-elevation myocardial infarction (STEMI) but ultimately attributed to an aortic aneurysm. Despite facing initial challenges in diagnosis, such as normal troponin levels and temporary electrocardiogram (ECG) changes, advanced imaging showed a large mass in the chest pressing on the right coronary artery. Prompt multidisciplinary intervention, including surgical resection of the aneurysm, led to successful management and improved outcomes. This case highlights the importance of considering unusual etiologies in atypical presentations of myocardial infarction, necessitating comprehensive evaluation and collaboration among various specialties for optimal patient care.</p>","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11268006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141751873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dermatomyositis Associated With High-Grade B-Lymphoproliferative Disorders: A Case Report and Literature Review. 皮肌炎伴发高级别 B 淋巴增生性疾病：病例报告与文献综述
IF 0.9
Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241262702
Jun Yen Ng, Mridula Mokoonlall, Hana Kawatu, Fathima Ayyalil, Chandima Perera, Adrienne Morey, Nalini K Pati
{"title":"Dermatomyositis Associated With High-Grade B-Lymphoproliferative Disorders: A Case Report and Literature Review.","authors":"Jun Yen Ng, Mridula Mokoonlall, Hana Kawatu, Fathima Ayyalil, Chandima Perera, Adrienne Morey, Nalini K Pati","doi":"10.1177/23247096241262702","DOIUrl":"10.1177/23247096241262702","url":null,"abstract":"<p><p>Dermatomyositis (DM) and polymyositis are idiopathic inflammatory myopathies (IIMs), most associated with solid organ malignancies, and less commonly hematological malignancies. We discuss a case of DM associated with diffuse large B-cell lymphoma, followed by a review of literature on the pathogenesis, clinical course, treatment, and prognosis. Various challenges with the diagnosis and management of underlying lymphoproliferative disorders (LPDs) in patients with IIM are discussed. The case demonstrates the importance of being vigilant of the association between IIM and LPD. Cancer screening in patients with IIM is discussed, including the recently published International Guideline for IIM-Associated Cancer Screening. More research is required to address knowledge gaps in cancer screening in IIM.</p>","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Recurrent Takotsubo Cardiomyopathy Complicated by Thromboemboli. 血栓栓塞并发复发性塔克次博心肌病的罕见病例
IF 0.9
Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241257394
Nismat Javed, Shoaib Ashraf, Amandeep Singh, Gayathri Kamalakkannan
{"title":"A Rare Case of Recurrent Takotsubo Cardiomyopathy Complicated by Thromboemboli.","authors":"Nismat Javed, Shoaib Ashraf, Amandeep Singh, Gayathri Kamalakkannan","doi":"10.1177/23247096241257394","DOIUrl":"10.1177/23247096241257394","url":null,"abstract":"<p><p>Takotsubo syndrome (TTS) is a transient ventricular dysfunction with apical ballooning triggered by emotional and/or physical stress. A few risk factors have been observed in patients with recurrent TTS, for example, excessive sympathetic stimuli, medications, stress, and tumors. Clinical features can vary from chest pain to overt hemodynamic instability. Diagnosis requires both electrocardiographic features and invasive imaging such as angiography to rule out other causes of cardiomyopathy prior to diagnosis. In addition, renal infarcts presenting as a complication of TTS are relatively uncommon. In this case report, we discuss the case of a 61-year-old African American woman with a prior history of TTS being managed for abdominal pain who developed a recurrence of the TTS during the hospital course. Prompt diagnosis and management of the condition is crucial to improve outcomes especially in patients with thromboembolic phenomenon or hemodynamic instability. Further large-scale studies are warranted to determine outcomes of patients with recurrent Takotsubo cardiomyopathy with thromboembolic phenomenon.</p>","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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