Journal of investigative medicine high impact case reports最新文献_第10页

Can Nondisplacement Osteoporotic Pubic Rami Fracture Be Life-Threatening Injuries? A Case Report, Overview, and Algorithm Protocol for Management. 非置换性骨质疏松性耻骨骨嵴骨折会是危及生命的损伤吗？病例报告、概述和处理算法规程。

IF 1.2

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241231648

Grigorios Kastanis, Anna Pantouvaki, Mikela-Rafaella Siligardou, Constantinos Chaniotakis, Emmanouil Kroustalakis, Ioannis Stavrakakis, Petros Kapsetakis

{"title":"Can Nondisplacement Osteoporotic Pubic Rami Fracture Be Life-Threatening Injuries? A Case Report, Overview, and Algorithm Protocol for Management.","authors":"Grigorios Kastanis, Anna Pantouvaki, Mikela-Rafaella Siligardou, Constantinos Chaniotakis, Emmanouil Kroustalakis, Ioannis Stavrakakis, Petros Kapsetakis","doi":"10.1177/23247096241231648","DOIUrl":"10.1177/23247096241231648","url":null,"abstract":"Pubic rami fractures in the geriatric population are usually osteoporotic fractures resulting from low energy trauma and are characterized as stable injuries. Established treatment of these injuries is conservative, including rest, analgesic medication, and progressive active mobilization. These injuries are life-threatened when pubic rami fractures are accompanied by acute bleeding, either from an injury to a vessel (corona mortis) or from medication (anticoagulant or antiplatelet) for comorbidities, then. In this case study, we present the unusual case of an 82-year-old woman admitted to the emergency department 24 hours after a simple fall, causing nondisplacement osteoporotic pubic rami fracture, who, after 48 hours, developed a hematoma on the contralateral side of the pelvis, with progressive anemia and acute abdominal pain. This study has 2 objectives: to increase awareness of this life-threatening injury in the emergency department and to describe diagnosis and treatment modalities.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":"12 ","pages":"23247096241231648"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10943755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140140372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Esophageal Perforation Presenting Initially as Multiple Brain Abscesses Secondary to Streptococcus intermedius. 食管穿孔最初表现为继发于中间链球菌的多发性脑脓肿。

IF 1.2

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241239572

Muhammed Yaman Swied, Mulham Alom, Obada Daaboul, Muaataz Azzawi, Abdul Swied

引用次数: 0

Coincident Thyrotoxic Hypokalemic Periodic Paralysis and Cardiomyopathy. 并发甲亢低钾周期性麻痹和心肌病

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241274276

Steven Swarath, Nicole Maharaj, Arun Katwaroo, Valmiki Seecheran, Rajeev Seecheran, Priya Ramcharan, Lakshmipathi Peram, Naveen Seecheran

引用次数: 0

Development of a Second Primary Lung Cancer Following a Primary Breast Cancer: A Case Series. 原发性乳腺癌后发展为第二原发性肺癌：病例系列。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241272013

Luz F Sua, Álvaro E Osorio, Valeria Zuñiga-Restrepo, Ciro D Ibarra, Natalia Quintero, Liliana Fernández-Trujillo

{"title":"Development of a Second Primary Lung Cancer Following a Primary Breast Cancer: A Case Series.","authors":"Luz F Sua, Álvaro E Osorio, Valeria Zuñiga-Restrepo, Ciro D Ibarra, Natalia Quintero, Liliana Fernández-Trujillo","doi":"10.1177/23247096241272013","DOIUrl":"10.1177/23247096241272013","url":null,"abstract":"Breast cancer (BC) accounts for 24.2% of all women's malignant tumors, with rising survival rates due to advancements in chemotherapy and targeted treatments. However, second primary cancers, particularly lung cancer (LC), have become more prevalent, often emerging approximately 10 years after BC treatment. This study presents a case series of 9 women diagnosed with second primary LC following BC, treated at a high-complexity hospital in Colombia between 2014 and 2019. All initial BCs were ductal carcinomas, 7 were triple negative, 1 was human epidermal growth factor receptor 2 positive, and 1 was estrogen and progesterone positive. Each patient had undergone radiation therapy, and 7 had received chemotherapy, increasing their LC risk. The second primary LCs, all adenocarcinomas, were confirmed using immunohistochemical stains for thyroid transcription factor-1 (TTF-1), Napsin A, and estrogen receptor (ER) status. The interval between treatments and LC detection ranged from 1 to 17 years, with 4 cases identified after 10 years and 3 within 1 to 3 years, underscoring the need for prolonged surveillance. Seven LCs were ipsilateral to the BC and radiation site, while 2 were contralateral, highlighting the necessity of monitoring both sides for potential LC development. This case series enhances the local epidemiological understanding, showing that prior radiotherapy for BC and histological analysis are key in characterizing second primary LC patients. The study emphasizes the critical role of accurate histological diagnosis in guiding treatment approaches for lung lesions in BC survivors.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":"12 ","pages":"23247096241272013"},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11468341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary Gastric Atypical Burkitt Lymphoma: A Rare Case Report.

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241298147

Jing Zheng, Mustafa Wasifuddin, Richard Wu, Akhtar Cheema, Beka Aroshidze, Boris Avezbakiyev, Jen C Wang

引用次数: 0

The Harms of Unnecessary CT Pulmonary Angiography: A Case Report and Literature Review. 不必要的 CT 肺血管造影的危害：病例报告与文献综述

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241258603

Zakaria Alagha, Ean Bills, Maha Alastal, Muhammad Ghallab, Amro Al-Astal, Ahmed Mahdi

引用次数: 0

Pulmonary Contusion-An Unusual Clinical and Radiological Presentation: Case Report. 肺挫伤--一种不寻常的临床和放射学表现：病例报告。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241266089

Ana Isabel Castrillón, Luz F Sua, Alvaro Sanchez, Liliana Fernández-Trujillo

{"title":"Pulmonary Contusion-An Unusual Clinical and Radiological Presentation: Case Report.","authors":"Ana Isabel Castrillón, Luz F Sua, Alvaro Sanchez, Liliana Fernández-Trujillo","doi":"10.1177/23247096241266089","DOIUrl":"10.1177/23247096241266089","url":null,"abstract":"Pulmonary contusion (PC), defined as damage to the lung parenchyma with edema and hemorrhage, has classically been associated with acceleration-deceleration injuries. It is a frequent pathology in clinical practice. However, its clinical presentation and imaging findings are nonspecific. Patients with this entity can present with findings that can range from mild dyspnea to life-threatening respiratory failure and hemodynamic instability. We present the case of a 61-year-old man, a former smoker, who presented to the emergency department after suffering blunt chest trauma. On admission, he complained of only mild shortness of breath, and his vital signs were typical. Initial imaging identified asymmetric pulmonary infiltrates and mediastinal lymphadenopathy; this was suspicious for additional pathology in addition to PC. After an exhaustive evaluation, a neoplastic or infectious disease process was ruled out. Even though the patient presented with a clinical deterioration of respiratory function compatible with secondary acute respiratory distress syndrome, there was a complete recovery after supportive measures and supplemental oxygen. In conclusion, the nonspecific clinical and imaging findings in patients with pulmonary contusion warrant a complete evaluation of these cases. An early diagnosis is essential to establish adequate support and monitoring to prevent possible complications that could worsen the patient's prognosis.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":"12 ","pages":"23247096241266089"},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11273703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141759207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Impressive Response to Zoldronic Acid Treatment for Chronic Recurrent Multifocal Osteomyelitis: A Case Report. 唑膦酸治疗慢性复发性多灶性骨髓炎疗效显著：病例报告。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241289190

Nabaa Ihsan Awadh, Faiq I Gorial, Khalid Burhan Khalid, Ahmed Dheyaa Al-Obaidi, Adil Saudi Khudhair, Noor Abbas Hummadi Fayadh

{"title":"An Impressive Response to Zoldronic Acid Treatment for Chronic Recurrent Multifocal Osteomyelitis: A Case Report.","authors":"Nabaa Ihsan Awadh, Faiq I Gorial, Khalid Burhan Khalid, Ahmed Dheyaa Al-Obaidi, Adil Saudi Khudhair, Noor Abbas Hummadi Fayadh","doi":"10.1177/23247096241289190","DOIUrl":"10.1177/23247096241289190","url":null,"abstract":"Chronic recurrent multifocal osteomyelitis (CRMO) is a rare, non-infectious inflammatory disease with a prevalence of 1 to 2/106, causing multiple lytic bone lesions. There are no established protocols for treating CRMO; thus, current practice is largely empirical. Data on the use of zoledronic acid (ZA) in juvenile CRMO are scarce. A 12-year-old male child with a history of multiple aseptic osteomylitis, affecting the chest wall, right ankle, and wrist, had no fever. Cultures and a bone biopsy ruled out infection or malignancy. The patient's condition stayed stable while taking naproxen (20 mg/kg/day) and methotrexate (10 mg/week) for 1.5 years until he experienced right elbow pain, swelling, no overlying skin erythema, and a restricted range of motion. The laboratory tests all came back normal, including white blood cell (WBC) count, erythrocyte sedimentation rate, C-reactive protein, and immunoglobin assays. The magnetic resonance imaging showed a focal lesion in the medial humeral condyle with increased signal intensity on T2 and short tau inversion recovery, mild joint effusion, and no cortical break. Thus, intravenous ZA infusion commenced at 0.0125 mg/kg initially, followed by 0.025 mg/kg 3 months later, with a marked improvement in the patient's clinical symptoms and radiological findings. Non-steroidal anti-inflammatory drugs and methotrexate were initially effective in treating our patient's condition, but a recurrence necessitated treatment modification. To the best of our knowledge, this case is the first documented instance of the use of ZA in CRMO in Iraq and Arab nations.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":"12 ","pages":"23247096241289190"},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enteric Duplication Cyst Associated With Meckel's Diverticulum: A Rare Cause of Acute Abdomen. 伴有梅克尔憩室的肠套叠囊肿：急性腹部的罕见病因。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241271986

Kugendran Ponniah, Stephen Kinsey-Trotman, Naveen Agarwal, Dandie Lachlan, Matthew Kozman

引用次数: 0

Küttner's Tumor and Autoimmune Pancreatitis as Metachronous Manifestations of IgG4-Related Disease. 库特纳肿瘤和自身免疫性胰腺炎是IgG4相关疾病的同步表现

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241286368

Lefika Bathobakae, Rammy Bashir, Heba Farhan, Aneeqa Shahid, Katrina Villegas, Gabriel Melki, Kamal Amer, Yana Cavanagh

{"title":"Küttner's Tumor and Autoimmune Pancreatitis as Metachronous Manifestations of IgG4-Related Disease.","authors":"Lefika Bathobakae, Rammy Bashir, Heba Farhan, Aneeqa Shahid, Katrina Villegas, Gabriel Melki, Kamal Amer, Yana Cavanagh","doi":"10.1177/23247096241286368","DOIUrl":"10.1177/23247096241286368","url":null,"abstract":"Immunoglobulin G4-related disease (IgG4-RD) is a multiorgan, fibro-inflammatory condition that presents with painless organ swelling, lymphoplasmacytic infiltration, and obliterative phlebitis, often showing a favorable response to corticosteroid therapy. The most affected organs include the pancreas, kidneys, retroperitoneum, lacrimal glands, and salivary glands. Diagnosis relies on serological, imaging, and histopathological findings, with glucocorticoids as the primary treatment. Despite its reversible nature and good prognosis in many cases, long-term complications such as organ dysfunction or malignancy can still occur. International collaborative efforts have enhanced the understanding, diagnosis, and management of IgG4-RD, emphasizing the importance of comprehensive diagnostic criteria and appropriate therapeutic strategies. Herein, we present an interesting case of a geriatric male who was referred to our clinic because of concern for pancreatic cancer. We diagnosed the patient with autoimmune pancreatitis, a manifestation of IgG4-RD. The patient experienced a dramatic response to steroid therapy and is currently on maintenance therapy.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":"12 ","pages":"23247096241286368"},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11457198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142377961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0