Journal of biomedical materials research. Part B, Applied biomaterials最新文献

{"title":"Synthesis Biomass Carbon Dots Derived From Carboxymethyl Chitosan and Epigallocatechin Gallate Both Antimicrobial and Antioxidation via a One-Step Hydrothermal Method","authors":"Bingli Du,&nbsp;Jin Qi,&nbsp;Yanling Mi,&nbsp;Ran Zhang,&nbsp;Juan Ren,&nbsp;Yajuan Gong,&nbsp;Jiadi Li,&nbsp;Shuo Huang,&nbsp;Bing Li,&nbsp;Xiuping Wu","doi":"10.1002/jbm.b.35630","DOIUrl":"https://doi.org/10.1002/jbm.b.35630","url":null,"abstract":"<div>\u0000 \u0000 <p>The resistance and biocompatibility of traditional antibiotics is a potential challenge for bacterial infections. Bacterial infections can produce oxidative stress, which can hamper cell migration and repair. In recent years, nanomaterials have become a viable alternative therapy for treating bacterial infections, with carbon dots (CDs) receiving popularity due to their superior characteristics. As a result, in this experiment, carboxymethyl chitosan (CMC) and epigallocatechin gallate (EGCG) were used as carbon sources, and multifunctional biomass green CDs with good biocompatibility, high antibacterial activity, potent antioxidant capacity, and the ability to promote cell migration and repair were synthesized by a one-step hydrothermal method. The cytotoxicity assay findings demonstrated that CDs had high biocompatibility and promoted cell growth at the concentration of 100 μg mL⁻¹. The results of the antibacterial experiment showed that CDs had a strong antibacterial effect upon <i>Staphylococcus aureus</i> and <i>Escherichia coli</i>. At the same time, CDs can eliminate ROS and protect cells from oxidative stress damage, which improves the cell's capacity to migrate and repair. The biomass green CDs provide a way to develop multifunctional carbon-based nanomaterials and provide a certain potential value for the promotion of wound healing and the clinical transformation of nanomaterials in the future.</p>\u0000 </div>","PeriodicalId":15269,"journal":{"name":"Journal of biomedical materials research. Part B, Applied biomaterials","volume":"113 8","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Mechanical Characterization of Amniotic-Based Scaffolds Containing Silk Fibroin and Sodium Alginate Nanofibers\".","authors":"","doi":"10.1002/jbm.b.35603","DOIUrl":"https://doi.org/10.1002/jbm.b.35603","url":null,"abstract":"","PeriodicalId":15269,"journal":{"name":"Journal of biomedical materials research. Part B, Applied biomaterials","volume":"113 8","pages":"e35603"},"PeriodicalIF":3.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"‘Smart’ Polymer Sandwiches From Hydrogel Nanocoatings Attached to Stimuli-Responsive Grafted Brush Coatings: Changing the Cell Behavior","authors":"Yana Shymborska,&nbsp;Svitlana Tymetska,&nbsp;Andrzej Budkowski,&nbsp;Joanna Zemła,&nbsp;Joanna Raczkowska,&nbsp;Kamil Awsiuk,&nbsp;Andrzej Bernasik,&nbsp;Małgorzata Lekka,&nbsp;Alex A. Volinsky,&nbsp;Joanna Pabijan,&nbsp;Yurij Stetsyshyn","doi":"10.1002/jbm.b.35631","DOIUrl":"https://doi.org/10.1002/jbm.b.35631","url":null,"abstract":"<div>\u0000 \u0000 <p>In an effort to provide a universal platform for remotely controlling the behavior of various cell lines, we present a strategy for fabricating ‘smart’ polymer sandwiches using a nanogel attached to temperature-responsive grafted brush coatings. These coatings can be easily modified to meet the requirements of specific cell types while preserving responsiveness. First, temperature-responsive grafted copolymer brush coatings of poly(oligo(ethylene glycol) methyl ether methacrylate) (POEGMA) with a small amount of hydroxyethyl methacrylate (HEMA) were synthesized on glass surfaces. Subsequent modifications involved using multifunctional alcohols, amines, or their combinations with proteins to react with divinyl sulfone, forming a cross-linked polymer matrix with a surface nanogel structure attached to grafted copolymer brushes containing hydroxyl groups. The resulting sandwich coatings were comprehensively characterized, revealing maintained temperature-responsiveness for various structures of the grafted nanogel. Compared with P(OEGMA-co-HEMA) brushes, these temperature-responsive sandwich coatings exhibited improved biocompatibility while retaining the ability to regulate cell morphology and detachment of dermal fibroblasts through external temperature control. Rheological analysis of live cells was performed on the developed platforms to reveal their impact on cellular behavior. The application of these new materials opens exciting possibilities for tissue engineering.</p>\u0000 </div>","PeriodicalId":15269,"journal":{"name":"Journal of biomedical materials research. Part B, Applied biomaterials","volume":"113 8","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144758543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Secondary Non-Thermal Plasma Decontamination on Ethanol-Treated Endosteal Implant Surfaces: An In Vivo Study of Osseointegration","authors":"Adriana I. Sandino,&nbsp;Joao Arthur Kawase De Queiroz Goncalves,&nbsp;Pawan Pathagamage,&nbsp;Baylee M. Brochu,&nbsp;Savanah R. Sturm,&nbsp;Arthur Castellano,&nbsp;Vasudev Vivekanand Nayak,&nbsp;Lukasz Witek,&nbsp;Paulo G. Coelho","doi":"10.1002/jbm.b.35628","DOIUrl":"https://doi.org/10.1002/jbm.b.35628","url":null,"abstract":"<div>\u0000 \u0000 <p>Effective surface treatment of implants is essential for enhancing osseointegration outcomes. This study assessed the influence of alcohol decontamination both with and without secondary argon-based non-thermal plasma (NTP) treatment on osseointegration of endosteal implants in a large translational (sheep) model. Ti6Al4V dental implants were utilized either as received (CTRL), or subjected to ethanol cleaning (for 60 s) followed by NTP (for 60 s) (Clean+Plasma); or treated with NTP alone (Plasma) for 60 s. X-ray photoelectron spectroscopy was used for surface elemental analysis, followed by interferometry and sessile drop tests to measure changes in surface roughness and surface energy, respectively. Twelve sheep received implants (one implant per group per sheep) in the iliac crest, and bone healing was evaluated after 3 and 12 weeks using histomorphometric analysis (six sheep/time point). No significant differences in surface roughness (arithmetic mean (Sa) and root mean square (Sq) height: <i>p</i> &gt; 0.161 and <i>p</i> &gt; 0.173, respectively) or topographies were detected between implant surfaces. However, both NTP treated groups presented higher surface energies and lower water contact angle values relative to CTRL surface (<i>p</i> &lt; 0.001). Compared to the CTRL, both NTP-treated groups exhibited reduced levels of Carbon and elevated levels of Oxygen. No significant differences in Bone-to-Implant Contact (BIC) or Bone Area Fractional Occupancy (BAFO) were observed among groups at 3 weeks. At the 12-week time point, Plasma implants demonstrated significantly higher BAFO (<i>p</i> = 0.014) compared to the CTRL group, as well as an increase in both BIC and BAFO over time (3 vs. 12 weeks in vivo) (<i>p</i> = 0.041 and <i>p</i> = 0.043, respectively). Building on the existing literature, the current study suggests that NTP treatment alone may be adequate to successfully enhance osseointegration while minimizing contamination risks, thereby eliminating the need for additional cleaning protocols.</p>\u0000 </div>","PeriodicalId":15269,"journal":{"name":"Journal of biomedical materials research. Part B, Applied biomaterials","volume":"113 8","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144740120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Engineering a Highly Elastic Bioadhesive for Sealing Soft and Dynamic Tissues”","authors":"","doi":"10.1002/jbm.b.35624","DOIUrl":"https://doi.org/10.1002/jbm.b.35624","url":null,"abstract":"<p>\u0000 <span>M. Ghovvati</span>, <span>S. Baghdasarian</span>, <span>A. Baidya</span>, <span>J. Dhal</span>, and <span>N. Annabi</span>, “ <span>Engineering a Highly Elastic Bioadhesive for Sealing Soft and Dynamic Tissues</span>,” <i>Journal of Biomedical Materials Research Part B: Applied Biomaterials</i> <span>110</span>, no. <span>7</span> (<span>2022</span>): <span>1511</span><span>1522</span>, https://doi.org/10.1002/jbm.b.35012.\u0000 </p>","PeriodicalId":15269,"journal":{"name":"Journal of biomedical materials research. Part B, Applied biomaterials","volume":"113 8","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jbm.b.35624","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144717030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Novel Janus Biogel Bolus for Radiotherapy","authors":"Ying Lu,&nbsp;Shihang Li,&nbsp;Guobao Pang,&nbsp;Xin Yang,&nbsp;Guannan Zhang,&nbsp;Yannan Xu,&nbsp;Jia Li,&nbsp;Qinying Shi,&nbsp;Jianbo Song","doi":"10.1002/jbm.b.35621","DOIUrl":"https://doi.org/10.1002/jbm.b.35621","url":null,"abstract":"<div>\u0000 \u0000 <p>Bolus is crucial for treating superficial lesions in radiotherapy. However, mechanical adhesion and biological mismatches of Bolus materials often impact the outcome of radiotherapy. This study introduces asymmetrical Janus biogel Bolus with one adhesive side and another with minimal adhesion. The biogel was fabricated employing a synergistic combination of distinct materials through physical and chemical interactions. The upper layer mainly comprises acrylamide and trehalose, abbreviated as PT, while the lower layer consists of acrylamide, trehalose, protocatechuic acid, nanoclay, and resveratrol, abbreviated as PTPNR. Mechanical, biological, and radiological tests were conducted to evaluate the Janus patch as a functional and biocompatible Bolus. The PTPNR layer demonstrated skin adhesion (repetitive adhesion force of 8 kPa), antibacterial (&gt; 95%) and anti-inflammatory properties. The PT layer was a water retention and mechanical barrier (compression modulus ≈550 kPa). This Janus biogel design integrates principles from biomedical and engineering fields, making it suitable for use as a Bolus material in treating superficial tumors.</p>\u0000 </div>","PeriodicalId":15269,"journal":{"name":"Journal of biomedical materials research. Part B, Applied biomaterials","volume":"113 8","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144714769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Propolis-Infused Electrospun Eudragit/PVP Mats: A Novel Approach for Bioactive and Antibacterial Wound Dressings","authors":"Nazli Alizadeh,&nbsp;Yasir Q. Almajidi,&nbsp;Mastafa H. Al-Musawi,&nbsp;Mojtaba Abbasian,&nbsp;Hashim H. Al Zuaini,&nbsp;Marjan Ghorbani,&nbsp;Fatemeh Doustdar,&nbsp;Fatemeh Mortazavi Moghadam","doi":"10.1002/jbm.b.35625","DOIUrl":"https://doi.org/10.1002/jbm.b.35625","url":null,"abstract":"<div>\u0000 \u0000 <p>Electrospun mats with varying ratios of Eudragit L-100 (EU) to polyvinylpyrrolidone (PVP) were fabricated and characterized. Morphological analysis (FESEM), fiber diameter distribution, porosity measurements, degradability studies, and water vapor transmission rate (WVTR) assessments indicated that an EU/PVP ratio of 70:30 exhibited optimal properties. Propolis (PRO), known for its antimicrobial, antioxidant, and anti-inflammatory effects, was incorporated into the optimized mats at different weight percentages (5, 10, and 20 wt%). The inclusion of PRO resulted in increased fiber thickness and decreased porosity. PRO-loaded mats exhibited lower degradation rates and slightly enhanced tensile strength compared to the neat EU/PVP mats. A higher PRO content led to a reduction in WVTR, while radical scavenging activity increased to over 40%. Hemocompatibility and biocompatibility were confirmed through hemolysis tests, cell proliferation assays, cell attachment studies, and live/dead staining. Additionally, PRO-loaded mats exhibited antibacterial efficacy against <i>Escherichia coli</i> and <i>Staphylococcus aureus</i>. The sustained release of PRO from the EU/PVP matrix further supports its potential as an effective wound dressing.</p>\u0000 </div>","PeriodicalId":15269,"journal":{"name":"Journal of biomedical materials research. Part B, Applied biomaterials","volume":"113 8","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144714770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical Passivation of Titanium and Ti-6Al-4V Alloy and Impact on Biocompatibility: A Comprehensive 50-Year Review and Best Practice Guidelines","authors":"Gopinath Mani,&nbsp;Andreas Ornberg,&nbsp;Robert Shulfer,&nbsp;Marika Kamberi","doi":"10.1002/jbm.b.35626","DOIUrl":"https://doi.org/10.1002/jbm.b.35626","url":null,"abstract":"<div>\u0000 \u0000 <p>Chemical passivation is a standard surface finishing treatment applied to commercially pure Titanium (cp-Ti) and Titanium-6Aluminum-4Vanadium (Ti-6Al-4V) when preparing them for use in medical devices. Although this treatment has been widely used for over 50 years, there remains a lack of consensus regarding its precise impact on surface characteristics and subsequent biocompatibility. This article comprehensively reviews the literature on this topic and sheds light on the reasons behind the conflicting research findings even after decades of practice. First, the nitric acid-based passivation protocol, originally developed for stainless steel, is often directly applied to cp-Ti and Ti-6Al-4V without specific optimization studies. Second, the pre-treatment processes, pre-cleaning procedures, and passivation protocols are significantly varied among the studies in the literature to provide vastly different outcomes regarding surface properties and subsequent material performance. Third, the ASTM F86 standard, commonly used in many studies, has several limitations. It provides open-ended recommendations for certain parameters (such as acid treatment time) without specifying maximum limits, lacks clearly defined validation processes, and relies on inadequate inspection methods (like visual examination). These limitations result in significant variations in outcomes and incomplete characterizations. Fourth, the surface characteristics subjected to chemical passivation differ due to the diverse manufacturing processes used in the studies. This results in varying outcomes, even when the same passivation protocol is employed. Considering the various shortcomings in the literature, a set of best practice recommendations is provided to enhance the reliability and consistency of research outcomes in the chemical passivation of cp-Ti and Ti-6Al-4V.</p>\u0000 </div>","PeriodicalId":15269,"journal":{"name":"Journal of biomedical materials research. Part B, Applied biomaterials","volume":"113 8","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Vivo Assessment of Trimetaphosphate Nanocomposite-Based Polyamide-6 Scaffolds Enhanced With Silver Nanoparticles for Bone Regeneration","authors":"Maria Juliana Sismeiro Dias Morabito,&nbsp;Gabriel Pereira Nunes,&nbsp;Edilson Ervolino,&nbsp;Maria José Hitomi Nagata,&nbsp;Francisco Nunes de Souza Neto,&nbsp;Emerson Rodrigues de Camargo,&nbsp;Alberto Carlos Botazzo Delbem","doi":"10.1002/jbm.b.35623","DOIUrl":"https://doi.org/10.1002/jbm.b.35623","url":null,"abstract":"<div>\u0000 \u0000 <p>The aim of this study was to evaluate the influence of nanocomposite materials, specifically sodium trimetaphosphate (TMP) nanoparticles decorated with 2.5% silver nanoparticles (AgNP), incorporated into polyamide-6 (Pa6) polymeric matrices on bone repair in surgically created critical-size defects in rat calvaria. Eighteen male Wistar rats were divided into three groups based on the treatment received: control group (C)—blood clot; Pa6-AgNP; and Pa6-TMP-AgNP. A 5 mm diameter defect was created in the calvaria of each animal. In Group C, the defect was filled with blood clots only, while the other groups were filled with scaffolds containing Pa6-AgNP and Pa6-TMP-AgNP. After 30 days post-surgery, the animals were euthanized, and microtomographic, histomorphometric, and immunohistochemical analyses were performed. The area of newly formed bone was calculated as a percentage of the total area of the original defect, and immunostaining for TGFβ-1, BMP-2/4, and OCN was assessed. Intergroup analysis revealed that the Pa6-TMP-AgNP group exhibited a greater volume of newly formed bone, while the Pa6-AgNP group showed a significantly increased bone formation compared to the control group (<i>p</i> &lt; 0.05). Immunohistochemistry indicated that the Pa6-TMP-AgNP and Pa6-AgNP groups showed high and moderate immunostaining for TGFβ-1 and OCN, respectively. Additionally, the Pa6-TMP-AgNP group had a higher number of BMP-2/4 positive cells compared to the other groups (<i>p</i> &lt; 0.001). Based on these results, it can be concluded that Pa6-TMP-AgNP provides a biological response conducive to bone neoformation, exhibiting osteoinductive and osteoconductive properties when used to fill critical-size defects in rat calvaria.</p>\u0000 </div>","PeriodicalId":15269,"journal":{"name":"Journal of biomedical materials research. Part B, Applied biomaterials","volume":"113 8","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Corrosion Behavior of Brushite-Coated Magnesium in Different Environments: Non-Hematoma vs. Hematoma","authors":"Yu Yusa,&nbsp;Yoshinaka Shimizu,&nbsp;Yoshimoto Okada,&nbsp;Masanobu Hayashi,&nbsp;Takayuki Aizawa,&nbsp;Mayuko Izumi,&nbsp;Akimitsu Sato,&nbsp;Chieko Miura,&nbsp;Yoshimichi Imai","doi":"10.1002/jbm.b.35622","DOIUrl":"https://doi.org/10.1002/jbm.b.35622","url":null,"abstract":"<p>The corrosion rate of these alloys is observed to be the fastest immediately after implantation. In addition, bleeding can accelerate corrosion and cause treatment failure in vivo, and therefore, it is necessary to optimize the corrosion rate. The brushite (CaHPO₄・2H₂O) coating treatment, a type of calcium phosphate, is used as a method to optimize the corrosion rate of magnesium and is expected to have the same coating effect under hematoma as under non-hematoma conditions. The purpose of this study was to evaluate the effect of brushite coating treatment with and without hematoma up to 14 days of implantation in vivo experiments. Specimens of cylindrical Pure Magnesium (99.9%, 1.2 mm × 6 mm), treated with a brushite coating by precipitation, were implanted in hematoma or non-hematoma rat femurs. The insoluble salts that precipitated on the specimens were analyzed by inductively coupled plasma mass spectrometry, scanning electron microscopy-energy dispersive X-ray analysis, and Raman spectroscopy. Results showed that weight loss at 14 days of implantation in the hematoma group (24.83 ± 2.26 μg mm⁻²) was significantly greater than in the non-hematoma group (18.88 ± 1.95 μg mm⁻²). The hematoma group had increased precipitation of insoluble salt magnesium and phosphorus. However, the amount of magnesium contained in insoluble salt per weight loss was significantly greater in the non-hematoma group at all time points, particularly after 1 days of implantation (non-hematoma group: 19.42% ± 3.56%; hematoma group: 10.73% ± 0.41%, <i>p</i> &lt; 0.01). The brushite coating transformed the insoluble salts in the surface layer to an optimum structure compatible with the implantation environment. This enhanced the coating's protective function and more effectively inhibited magnesium corrosion. Given the clinical challenge of fully controlling intra-and postoperative bleeding, a brushite coating adaptable to hematoma conditions offers significant utility.</p>","PeriodicalId":15269,"journal":{"name":"Journal of biomedical materials research. Part B, Applied biomaterials","volume":"113 8","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jbm.b.35622","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}