Advanced Materials Interfaces最新文献_第8页

Tailoring Nanopore Geometry in Anodic Aluminum Oxide Membranes through Physical Stretching and Controlled Anodization 裁剪纳米孔几何在阳极氧化铝膜通过物理拉伸和控制阳极氧化

IF 4.3 3区材料科学

Advanced Materials Interfaces Pub Date : 2025-01-09 DOI: 10.1002/admi.202400699

Yu-Chun Liu, Yi-Fan Chen, Yu-Chun Lin, You-Hao Zheng, Lin-Ruei Lee, Ming-Hsuan Chang, Jhih-Hao Ho, Yu-Liang Lin, Jiun-Tai Chen

{"title":"Tailoring Nanopore Geometry in Anodic Aluminum Oxide Membranes through Physical Stretching and Controlled Anodization","authors":"Yu-Chun Liu, Yi-Fan Chen, Yu-Chun Lin, You-Hao Zheng, Lin-Ruei Lee, Ming-Hsuan Chang, Jhih-Hao Ho, Yu-Liang Lin, Jiun-Tai Chen","doi":"10.1002/admi.202400699","DOIUrl":"https://doi.org/10.1002/admi.202400699","url":null,"abstract":"The fabrication and application of anodic aluminum oxide (AAO) membranes with tailored nanopore geometries have profound implications in materials science and engineering. This study introduces a refined physical stretching method combined with precisely controlled anodization conditions to manipulate the anisotropy of nanopores in AAO membranes. By employing high-purity aluminum sheets and varying electrolytes such as sulfuric acid, oxalic acid, and phosphoric acid, anisotropic shapes are carried out with aspect ratios varying based on the applied mechanical forces and electrolytic conditions. The capability to produce AAO membranes with non-uniform pore distributions is also demonstrated by applying irregular stretching forces, revealing the potential for creating customized nanostructures. The anisotropic AAO membranes serve as effective templates for synthesizing polymer nanorods, indicating their utility in guiding the formation of advanced nanomaterials with specific directional properties. Our results showcase the role of mechanical and chemical parameters in tailoring nanoscale material properties. The versatility of horizontally anisotropic AAO membranes in nanofabrication enables better control of nanopore geometry for applications in nanoelectronics, drug delivery, and biosensing.","PeriodicalId":115,"journal":{"name":"Advanced Materials Interfaces","volume":"12 6","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admi.202400699","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143645954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pump-Probe Imaging of Ultrafast Laser Percussion Drilling of Glass in Single Pulse, MHz- and GHz-Burst Regimes 单脉冲、MHz和ghz脉冲下超快激光冲击打孔玻璃的泵探成像

IF 4.3 3区材料科学

Advanced Materials Interfaces Pub Date : 2025-01-09 DOI: 10.1002/admi.202400853

Pierre Balage, Théo Guilberteau, Manon Lafargue, Guillaume Bonamis, Clemens Hönninger, John Lopez, Inka Manek-Hönninger

{"title":"Pump-Probe Imaging of Ultrafast Laser Percussion Drilling of Glass in Single Pulse, MHz- and GHz-Burst Regimes","authors":"Pierre Balage, Théo Guilberteau, Manon Lafargue, Guillaume Bonamis, Clemens Hönninger, John Lopez, Inka Manek-Hönninger","doi":"10.1002/admi.202400853","DOIUrl":"https://doi.org/10.1002/admi.202400853","url":null,"abstract":"A pump-probe shadowgraphy study of femtosecond laser percussion drilling on glass samples is reported applying three different operating regimes, which are the standard repetitive single pulse, the MHz- and the GHz-burst modes. The comparison of pump-probe imaging in the MHz-burst and the GHz-burst regimes is demonstrated for the first time to the best of knowledge. Synchronizing a single pulse probe with a pump operating in a burst regime constitutes a real novelty in femtosecond laser micromachining studies. By this means, a better understanding of the drilling process dynamics of the two burst regimes is provided and reveals the differences between these regimes. Especially, the process of through via drillings of different hole depths in the GHz-burst regime is investigated in sodalime glass. The results of the pump-probe shadowgraphy show that the ablation plume in the GHz-burst regime has an essential role in the drilling process as it stops as soon as the plume escapes from the through hole explaining the final hole morphology observed for deep through via drillings.","PeriodicalId":115,"journal":{"name":"Advanced Materials Interfaces","volume":"12 10","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admi.202400853","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Droplet Microarrays for Miniaturized and High-Throughput Experiments: Progress and Prospectives 微滴微阵列的小型化和高通量实验：进展与展望

IF 4.3 3区材料科学

Advanced Materials Interfaces Pub Date : 2025-01-09 DOI: 10.1002/admi.202400905

D.D. Kartsev, Urrutia Gómez Joaquin E, Popova A. Anna, Pavel A. Levkin

{"title":"Droplet Microarrays for Miniaturized and High-Throughput Experiments: Progress and Prospectives","authors":"D.D. Kartsev, Urrutia Gómez Joaquin E, Popova A. Anna, Pavel A. Levkin","doi":"10.1002/admi.202400905","DOIUrl":"https://doi.org/10.1002/admi.202400905","url":null,"abstract":"Miniaturization in life sciences and chemical sciences offers substantial advantages to experimental workflows, such as increased throughput, reduced costs, and lower environmental impact. While microtiter plates are effective, further miniaturization is necessary to enhance efficiency and throughput. However, microtiter plates cannot be easily miniaturized to volumes below 5 µL, primarily because adhesive and capillary forces become stronger than the gravitational forces needed to confine the liquid within the wells. To overcome this, the droplet microarray (DMA) is developed, utilizing patterned adhesive regions on a liquid-repellent background to immobilize and confine sub-microliter droplets without physical barriers. This unique format enables novel applications such as droplet merging and parallel ultra-high-throughput manipulations. This review provides an overview of DMA's diverse applications and highlights the new experimental opportunities it offers, establishing it as a versatile tool for highly miniaturized, high-throughput biological and chemical experiments. The evolving requirements and future applications of the DMA approach are also discussed.","PeriodicalId":115,"journal":{"name":"Advanced Materials Interfaces","volume":"12 4","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admi.202400905","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143431159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microneedles with Interdigitated Electrodes for In Situ Impedimetric VEGF Sensing 带有交叉指状电极的微针用于原位阻抗性VEGF检测

IF 4.3 3区材料科学

Advanced Materials Interfaces Pub Date : 2025-01-09 DOI: 10.1002/admi.202400789

Ritu Das, Emin Istif, Rumeysa Cebecioglu, Mohsin Ali, Yasin Atik, Çağdaş Dağ, Eda Celikbas, Gozde Demirci, FundaYagcı Acar, Murat Hasanreisoğlu, Levent Beker

{"title":"Microneedles with Interdigitated Electrodes for In Situ Impedimetric VEGF Sensing","authors":"Ritu Das, Emin Istif, Rumeysa Cebecioglu, Mohsin Ali, Yasin Atik, Çağdaş Dağ, Eda Celikbas, Gozde Demirci, FundaYagcı Acar, Murat Hasanreisoğlu, Levent Beker","doi":"10.1002/admi.202400789","DOIUrl":"https://doi.org/10.1002/admi.202400789","url":null,"abstract":"Continuous monitoring of protein biomarkers in interstitial fluid (ISF) is essential for improving patient care and outcomes. This study presents a novel electrochemical impedance spectroscopy (EIS) sensor utilizing microneedles (MNs) patterned with interdigitated electrodes for the detection of vascular endothelial growth factor (VEGF). The MNs, are fabricated from flexible polylactide (PLA) using a simple molding technique, followed by metal deposition with an interdigitated pattern to serve as a platform for the EIS sensor. After functionalization with anti-VEGF antibodies, impedance measurements are conducted to detect VEGF levels, demonstrating a significant change in impedance in response to varying concentrations of the target biomarker. The MNs can easily penetrate rat skin by hand, puncturing without mechanical breakage. This innovative approach enhances the sensitivity and specificity of biomarker detection and paves the way for continuous monitoring applications in diagnostics and preventative medicine.","PeriodicalId":115,"journal":{"name":"Advanced Materials Interfaces","volume":"12 9","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admi.202400789","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Post-Sintering Heat Treatment on the Phase and Microstructural Development of Nano Cu-Zno Modified Ceramic Surfaces 烧结后热处理对纳米Cu-Zno改性陶瓷表面物相及显微组织发展的影响

IF 4.3 3区材料科学

Advanced Materials Interfaces Pub Date : 2025-01-09 DOI: 10.1002/admi.202400879

Nurcan Calis Acikbas, Gokhan Acikbas

{"title":"The Role of Post-Sintering Heat Treatment on the Phase and Microstructural Development of Nano Cu-Zno Modified Ceramic Surfaces","authors":"Nurcan Calis Acikbas, Gokhan Acikbas","doi":"10.1002/admi.202400879","DOIUrl":"https://doi.org/10.1002/admi.202400879","url":null,"abstract":"The study examines the effect of heat treatment duration on microstructure and phase evolution concerning Cu content in nano ZnO-Cu-modified ceramic glazes. The thermal behavior of the nano Cu-ZnO added glazes is investigated using heat microscopy and TG/DTA techniques to ascertain the appropriate firing and heat treatment temperature. Glazed tiles are sintered at 1210 °C for 10 min and heat treated at 965 °C for 2, 8, and 32 h. The surfaces are investigated with scanning electron microscopy and X-ray diffractometer. The evolution of phase and microstructure exhibits variations between sintered and heat-treated surfaces, dependent upon the concentration of Cu doping and heat treatment duration. The most important evidence is adding Cu into the ZnO-modified glaze leads to a stacked micro-nanostructure formation. The results show that while the willemite phase is dominant on the sintered surfaces, the size and quantity of fine plagioclase crystals increased with heat treatment and prolonged heat treatment time. The heat treatment period, depending on copper content, affects microstructure and phase development.","PeriodicalId":115,"journal":{"name":"Advanced Materials Interfaces","volume":"12 10","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admi.202400879","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Superior Hydrazine Electrooxidation Activities on Tin and Zirconium Promoted ZSM-5 Zeolite Catalyst ZSM-5沸石催化剂在锡和锆催化剂上具有优异的肼电氧化活性

IF 4.3 3区材料科学

Advanced Materials Interfaces Pub Date : 2025-01-09 DOI: 10.1002/admi.202400609

Derya Yıldız, Şefika Kaya, Omruye Ozok-Arici, Aykut Caglar, Arif Kivrak, Hilal Kivrak

{"title":"Superior Hydrazine Electrooxidation Activities on Tin and Zirconium Promoted ZSM-5 Zeolite Catalyst","authors":"Derya Yıldız, Şefika Kaya, Omruye Ozok-Arici, Aykut Caglar, Arif Kivrak, Hilal Kivrak","doi":"10.1002/admi.202400609","DOIUrl":"https://doi.org/10.1002/admi.202400609","url":null,"abstract":"Direct fuel cells, such as direct hydrazine fuel cells (DHFC), are considered environmentally friendly alternative energy technologies with great potential for the future. Hydrazine, used as a liquid fuel, is particularly advantageous due to its high cell voltage and energy density. In this study, the electrocatalytic potential of SnZr/ZSM-5 catalysts synthesized with wet impregnation at various molar ratios is investigated for hydrazine oxidation. The catalyst is characterized by XPS, ICP-MS, XRD, FTIR, SEM-EDX, and TEM techniques. Additionally, thermal characterization of this catalyst is performed with temperature-programmed reduction (TPR), temperature-programmed oxidation (TPO), and temperature-programmed desorption (TPD). The catalytic activities of ZSM-5-supported monometallic and bimetallic catalysts are determined using electrochemical measurements such as cyclic voltammetry (CV), chronoamperometry (CA), and electrochemical impedance spectroscopy (EIS) for direct hydrazine fuel cell (DHFC). The highest catalytic activity achieved is 44.874 mA cm−2 for SnZr(50:50)/ZSM-5 catalyst, revealing that Zr addition to Sn improves the electrocatalytic activity of bimetallic catalysts compared to monometallic catalysts. The long-term current density and stability of SnZr(50:50)/ZSM-5 catalyst are taken at 0.6 V. EIS measurements indicated that the lowest charge transfer resistance is at 0.6 V, consistent with CV and CA measurements. SnZr(50:50)/ZSM-5 provides a new perspective as an anode catalyst for DHFC applications.","PeriodicalId":115,"journal":{"name":"Advanced Materials Interfaces","volume":"12 5","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admi.202400609","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143497038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Controlling Frost Propagation on Polymeric Surfaces Using SI-ATRP Chemical Micropatterning 利用SI-ATRP化学微图案化技术控制聚合物表面霜的扩散

IF 4.3 3区材料科学

Advanced Materials Interfaces Pub Date : 2025-01-08 DOI: 10.1002/admi.202400838

Miisa J. Tavaststjerna, Stephen J. Picken, Santiago J. Garcia

{"title":"Controlling Frost Propagation on Polymeric Surfaces Using SI-ATRP Chemical Micropatterning","authors":"Miisa J. Tavaststjerna, Stephen J. Picken, Santiago J. Garcia","doi":"10.1002/admi.202400838","DOIUrl":"https://doi.org/10.1002/admi.202400838","url":null,"abstract":"Micropatterned surfaces with both hydrophilic and hydrophobic regions are relevant for a wide range of applications from fuel cells to water harvesting systems. The preferential nucleation of water on hydrophilic regions can also be used to control frost nucleation on chemically patterned surfaces. So far, this concept has been tested on brittle silicon surfaces with only a few different sizes and shapes of hydrophilic regions. In this work, the concept of controlled icing is investigated on five polymeric surfaces with different surface energies modified by micropatterning them with three types of hydrophilic polymer brushes. Frost formation and propagation on the resulting patterned surfaces with regions of varying wettability is monitored and quantified using high-resolution thermal imaging. The study proves that control over frost nucleation and propagation using regions of varying wettability can be achieved on commodity polymers. In addition to influencing the time and location of ice nucleation, the local patterning affects the freezing propagation mode and rate due to its impact on the continuity and thickness of molecular water layers (MWL). These results show that local control over the state of MWLs is key to controlling both ice nucleation and propagation of freezing events on surfaces.","PeriodicalId":115,"journal":{"name":"Advanced Materials Interfaces","volume":"12 10","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admi.202400838","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144117942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ESCRT III Regulates Lysosomal Perinuclear Clustering by Inhibiting Kinesin 1 Leading to Agnps Cytotoxicity in Human Cells ESCRT III通过抑制激酶1介导人细胞Agnps细胞毒性调控溶酶体核周聚集

IF 4.3 3区材料科学

Advanced Materials Interfaces Pub Date : 2025-01-07 DOI: 10.1002/admi.202400944

Tiantian Liu, Aiguo Xie, Chao Xing, RuiZhe He, Wei Ni, Yinbo Peng, Peng Xu, Yong Fang

{"title":"ESCRT III Regulates Lysosomal Perinuclear Clustering by Inhibiting Kinesin 1 Leading to Agnps Cytotoxicity in Human Cells","authors":"Tiantian Liu, Aiguo Xie, Chao Xing, RuiZhe He, Wei Ni, Yinbo Peng, Peng Xu, Yong Fang","doi":"10.1002/admi.202400944","DOIUrl":"https://doi.org/10.1002/admi.202400944","url":null,"abstract":"Silver nanoparticles (AgNPs) are recognized for their strong antibacterial properties, particularly in applications such as wound and burn treatment; however, the mechanisms of AgNP-induced cytotoxicity remain inadequately defined. This study investigates the role of lysosomal dysfunction in AgNP-induced cytotoxicity, focusing on lysosomal perinuclear clustering (LPC) and its relationship with cellular apoptosis. Human fibroblast HS27 cells are treated with 24 µg mL−1 AgNPs over 48 h, and lysosomal dynamics, cellular localization, and apoptosis rates are analyzed through confocal microscopy and flow cytometry. Protein expression levels of charged multivesicular body protein 4B(CHMP4B) and Kinesin 1, which are central to lysosomal transport and membrane repair, are examined via western blotting. The findings reveal that AgNP exposure leads to LPC and an increase in apoptosis in a time-dependent manner, accompanied by reduced Kinesin 1 expression. Further, inhibition of CHMP4B and Kinesin 1 significantly promoted apoptosis, while their overexpression mitigated AgNP-induced cytotoxic effects, underscoring their essential roles in lysosomal integrity. This study provides new insights into the cellular pathways of AgNP-induced cytotoxicity, focusing on lysosomal transport disruption, and suggests potential molecular targets to reduce adverse effects in therapeutic applications. These results lay a foundation for optimizing AgNP efficacy and improving their safety profile in clinical settings.","PeriodicalId":115,"journal":{"name":"Advanced Materials Interfaces","volume":"12 10","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admi.202400944","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atmospheric Water Sorption Kinetics in Powder and Monolithic Metal–Organic Frameworks 粉末和整体金属-有机框架的大气水吸附动力学

IF 4.3 3区材料科学

Advanced Materials Interfaces Pub Date : 2025-01-07 DOI: 10.1002/admi.202400628

Jiawang Li, Guang Wang, Hongzhao Fan, Zhigang Li, Chi Yan Tso, Yanguang Zhou

{"title":"Atmospheric Water Sorption Kinetics in Powder and Monolithic Metal–Organic Frameworks","authors":"Jiawang Li, Guang Wang, Hongzhao Fan, Zhigang Li, Chi Yan Tso, Yanguang Zhou","doi":"10.1002/admi.202400628","DOIUrl":"https://doi.org/10.1002/admi.202400628","url":null,"abstract":"Metal–organic frameworks (MOFs) have been widely applied for adsorption applications owing to their high surface area and porosity. In this paper, the atmospheric water adsorption kinetics in a prototypical MOF with two forms, that is, powder and monolithic MOF-801, are systematically investigated. It is shown that the total pore volume (average pore diameter) of the monolithic MOF-801 is 0.831 cm3 g−1 (5.20 nm) which is much larger than that of powder MOF-801, that is, 0.488 cm3 g−1 (1.95 nm). Monolithic MOF-801 absorbs more water than powder MOF-801 at a relative humidity (RH) above 90%. However, between the RH ranges from 10% to 90%, its water uptake is significantly lower than that of the powder form. Molecular dynamics simulations demonstrate that the unexpected water uptake capacity of monolithic MOF-801 at RH of 10%∼90% is caused by the water film formed by the capillary condensation in these mesopores of monolithic MOF-801. The capillary force of the formed film can be overcome by water vapor pressure when RH is over 90%. These findings reveal the underlying mechanisms for water adsorption kinetics in both powder and monolithic MOFs, which can motivate and benefit the new passive cooling or water harvesting system design based on MOFs.","PeriodicalId":115,"journal":{"name":"Advanced Materials Interfaces","volume":"12 5","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admi.202400628","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143497035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leveraging Multifaceted Polyphenol Interactions: An Approach for Hair Loss Mitigation 利用多方面的多酚相互作用：一种减轻脱发的方法

IF 4.3 3区材料科学

Advanced Materials Interfaces Pub Date : 2025-01-06 DOI: 10.1002/admi.202400851

Eunu Kim, Geon Min Lee, Haeshin Lee

{"title":"Leveraging Multifaceted Polyphenol Interactions: An Approach for Hair Loss Mitigation","authors":"Eunu Kim, Geon Min Lee, Haeshin Lee","doi":"10.1002/admi.202400851","DOIUrl":"https://doi.org/10.1002/admi.202400851","url":null,"abstract":"Hair loss affects millions globally, creating a demand for safer, more effective treatments. Traditional treatments like minoxidil often have limited efficacy and side effects. This study explores tannic acid, a polyphenol, as a promising alternative, serving as a multifaceted adhesion mediator that binds to keratin on the hair surface and serves as a reservoir for functional molecules-salicylic acid (SCA), niacinamide (N), and dexpanthenol (DAL)-collectively termed SCANDAL. Tannic acid forms a stable coating on hair through hydrogen bonding, while its unbound phenolic sites sequester SCANDAL molecules, enabling their controlled release upon exposure to moisture. This gradual release delivers active molecules directly to hair follicles, enhancing hair health and mitigating hair loss. In a seven-day study with 12 human participants, an average reduction of 56.2 ± 18.2% in the number of shed hairs is observed compared to their baseline counts. The presence of tannic acid on the hair surface is confirmed via X-ray photoelectron spectroscopy (XPS), and the formation of tannic acid/SCANDAL complexes is visualized using transmission electron microscopy (TEM). This approach demonstrates that hair keratin surfaces can serve as large-area platforms for controlled release of therapeutic agents, addressing various challenges in hair and scalp health.","PeriodicalId":115,"journal":{"name":"Advanced Materials Interfaces","volume":"12 10","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admi.202400851","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144117835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0